CN209333537U - A kind of immediate dialysis device - Google Patents
A kind of immediate dialysis device Download PDFInfo
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- CN209333537U CN209333537U CN201821955705.9U CN201821955705U CN209333537U CN 209333537 U CN209333537 U CN 209333537U CN 201821955705 U CN201821955705 U CN 201821955705U CN 209333537 U CN209333537 U CN 209333537U
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- permeable membrane
- bag filter
- dialyzate
- sample
- layer semi
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Abstract
The utility model discloses a kind of immediate dialysis devices, including dialysate tank and bag filter, it is characterized by: the bag filter is placed in dialysate tank, dialyzate is accommodated in dialysate tank, sample liquid is accommodated in bag filter, the bag filter includes outer layer semi-permeable membrane and the internal layer semi-permeable membrane that is recessed inwardly, the dialyzate is flowed in the exterior space of outer layer semi-permeable membrane and internal layer semi-permeable membrane, inner space flowing of the sample liquid between outer layer semi-permeable membrane and internal layer semi-permeable membrane, dialyzate and sample liquid are pumped in dialysate tank and bag filter by constant flow pump, the two convective flow.The utility model uses the internal layer semi-permeable membrane being recessed inwardly, replacement area between sample liquid and dialyzate increases, improve dialytic efficiency, and dialyzate and sample liquid are flowed in convection type, osmotic pressure between the two increases, dialytic efficiency improves, and does not need constantly to replace the dialyzate after balance.
Description
Technical field
The utility model belongs to field of biotechnology, specifically, being related to a kind of immediate dialysis device.
Background technique
Dialysis is to be diffused into the principle of water or buffer through semi-permeable membrane by small molecule, and small molecule and macromolecular are separated
A kind of separating and purifying technology.In field of biotechnology, dialysis is mainly used for salinity in biological sample, surfactant is gone
It removes, buffer exchange or pH value adjustment, sample concentration etc..It is semi-transparent since the speed of dialysis depends on the aperture of semi-permeable membrane
The surface area of film and the osmotic pressure of semi-permeable membrane two sides；After the semi-permeable membrane for selecting a kind of specification, dialysis speed just mainly depends on
In latter two factor.In specific implementation process kind, dialysis is a kind of relatively time-consuming process, especially in the more feelings of sample size
Under condition, so a kind of device that can be reduced dialysis time is at a kind of demand when being dialysed.
A kind of protein purification, enrichment facility are disclosed application No. is 94238788.0 Chinese patent, including electrolytic cell, are seeped
Permeable membrane, electrolyte, amberplex, electrode, in a cell between be placed in two panels permeable membrane, control film spacing 0.2~2cm it
Between, sample to be tested enters between film, and by replacing film two sides different solutions medium, sample and solution medium and film two sides are molten between film
Liquid medium is constantly pumped into convection current from both direction, and sample to be tested balances between film with the diffusion of film two sides, reaches separation, purifying mesh
's.The device is simply easy to do, and can separate the protein of known isoelectric point, removal both sexes dielectric and protein concentrate.But its device
It needs to avoid conductive material in the production process, there is limitation, and lead to protein since the presence of electrode still has overheat
The phenomenon that denaturation.
In view of this special to propose the utility model.
Summary of the invention
The technical problem to be solved by the present invention is to overcome the deficiencies of the prior art and provide a kind of immediate dialysis dress
It sets.
In order to solve the above technical problems, the basic idea of the utility model adopting the technical scheme is:
A kind of immediate dialysis device, including dialysate tank and bag filter, it is characterised in that: the bag filter is placed in dialysate tank
In, dialyzate is accommodated in dialysate tank, sample liquid is accommodated in bag filter, and the bag filter includes outer layer semi-permeable membrane and is recessed inwardly
Internal layer semi-permeable membrane, the dialyzate are flowed in the exterior space of outer layer semi-permeable membrane and internal layer semi-permeable membrane, and sample liquid is semi-transparent in outer layer
Inner space flowing between film and internal layer semi-permeable membrane, the internal layer semi-permeable membrane of the bag filter are surrounded into perforative space, dialyzate
It flows into from one end of perforative space, flowed out from the other end of perforative space and is mixed with the dialyzate outside outer layer semi-permeable membrane.
Further scheme as the utility model: the bag filter includes the outer layer support frame and internal layer to play a supportive role
Support frame, outer layer semi-permeable membrane are located on the outside of outer layer support frame, and internal layer semi-permeable membrane is located on the outside of internal layer support frame.
Further scheme as the utility model: the bag filter further includes being located at outer layer support frame and internal layer support frame
The bag filter lid at both ends.
Further scheme as the utility model: including constant flow pump, sample container and dialysis fluid container, the sample holds
Device and constant flow pump piping connection, constant flow pump and bag filter piping connection, the dialysis fluid container and constant flow pump piping connection, constant current
Pump and dialysate tank piping connection.
Further scheme as the utility model: the bag filter two sides are equipped with sample inlet pipe and sample outlet pipe, constant current
Pump is arranged on sample inlet pipe.
Further scheme as the utility model: the dialysate tank both ends are equipped with dialyzate inlet pipe and dialyzate outlet pipe,
Constant flow pump is arranged on dialyzate inlet pipe.
Further scheme as the utility model: the dialysate tank upper end is equipped with dialysis can end, and end cap is equipped with and connects
Mouthful, the interface includes that dialyzate goes out interface tube, and sample inlet pipe interface and sample go out interface tube.
Further scheme as the utility model: including seal washer, the seal washer be located at dialysis can end and
Between dialysate tank.
Further scheme as the utility model: the bag filter is suspended in dialyzate by sample inlet pipe and sample outlet pipe
In.
After adopting the above technical scheme, the utility model has the advantages that compared with prior art.
1) bag filter has outer layer semi-permeable membrane and internal layer semi-permeable membrane, exterior space and internal layer of the dialyzate in outer layer semi-permeable membrane
It is flowed in the perforative space that semipermeable membrane surrounds, spatial flow of the sample liquid between outer layer semi-permeable membrane and internal layer semi-permeable membrane,
Replacement area between sample liquid and dialyzate increases, and improves dialytic efficiency.
2) dialyzate is circulated between dialysate tank, dialysis fluid container by constant flow pump, and sample liquid is existed by constant flow pump
It is circulated between bag filter, sample liquid container, and dialyzate and sample liquid are flowed in convection type, osmotic pressure between the two
Increase, dialytic efficiency improves, and does not need constantly to replace the dialyzate after balance.
Specific embodiment of the present utility model is described in further detail with reference to the accompanying drawing.
Detailed description of the invention
The a part of attached drawing as the utility model, is further understood from the utility model for providing, this is practical
Novel illustrative embodiments and their description are not constituteed improper limits to the present invention for explaining the utility model.
Obviously, the accompanying drawings in the following description is only some embodiments, to those skilled in the art, is not paying creation
Property labour under the premise of, can also be obtained according to these attached drawings other accompanying drawings.In the accompanying drawings:
Fig. 1 is Tthe utility model system structural schematic diagram；
Fig. 2 is the utility model bag filter structural schematic diagram.
In figure: 1, sample inlet pipe；2, sample outlet pipe；3, dialyzate outlet pipe；4, dialyzate inlet pipe；5, constant flow pump；6, constant current
Pump 7, bag filter；8, dialysate tank；9, dialysis can end；10, sample container；11, dialysis fluid container；12, outer layer carrier；13,
Internal layer carrier；14, bag filter lid；15, bag filter lid 16, internal layer semi-permeable membrane；17, outer layer semi-permeable membrane；Arrow direction table
Show liquid flow direction.
It should be noted that these attached drawings and verbal description are not intended to limit the design of the utility model in any way
Range, but illustrate the concept of the utility model for those skilled in the art by referring to specific embodiments.
Specific embodiment
It is practical new below in conjunction with this to keep the objectives, technical solutions, and advantages of the embodiments of the present invention clearer
The technical solution in embodiment is clearly and completely described in attached drawing in type embodiment, and following embodiment is for illustrating this
Utility model, but be not intended to limit the scope of the present invention.
In the description of the present invention, it should be noted that term " on ", "lower", "front", "rear", "left", "right",
The orientation or positional relationship of the instructions such as "vertical", "inner", "outside" be based on the orientation or positional relationship shown in the drawings, merely to
Convenient for describing the utility model and simplifying description, rather than the device or element of indication or suggestion meaning must have specific side
Position is constructed and operated in a specific orientation, therefore should not be understood as limiting the present invention.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " is pacified
Dress ", " connected ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integrally
Connection；It can be mechanical connection, be also possible to be electrically connected；It can be directly connected, it can also be indirectly connected through an intermediary.
For the ordinary skill in the art, can be understood with concrete condition above-mentioned term in the present invention specifically contain
Justice.
As shown in Figure 1, a kind of immediate dialysis device of the utility model, including dialysate tank 8 and bag filter 7, bag filter 7 are placed in
In dialysate tank 8, dialyzate is accommodated in dialysate tank 8, accommodates sample liquid in bag filter 7, bag filter 7 include outer layer semi-permeable membrane 17 and to
The internal layer semi-permeable membrane 16 of sunken inside, dialyzate are flowed in the exterior space of outer layer semi-permeable membrane 17 and internal layer semi-permeable membrane 16, sample liquid
Inner space flowing between outer layer semi-permeable membrane 17 and internal layer semi-permeable membrane 16, the internal layer semi-permeable membrane 16 being recessed inwardly increase
The contact surface between liquid and sample liquid is analysed, the speed of dialysis improves.
The internal layer semi-permeable membrane 16 of bag filter 7 is surrounded into perforative space, and dialyzate is flowed into from one end of perforative space, from running through
The other end in space is flowed out and is mixed with the dialyzate outside outer layer semi-permeable membrane 17, and internal layer semi-permeable membrane 16 defines perforative space, makes
Contact area between dialyzate and sample liquid has obtained maximized promotion, and the flowing of dialyzate makes the infiltration of semi-permeable membrane two sides
Pressure enhancing, dialysis speed improve.
Bag filter 7 as shown in Figure 2 includes the outer layer support frame 12 and internal layer support frame 13 to play a supportive role, outer layer semi-permeable membrane
17 are located at 12 outside of outer layer support frame, and internal layer semi-permeable membrane 16 is located at 13 outside of internal layer support frame, outer layer support frame 12 and internal layer branch
The both ends of support 13 are equipped with bag filter lid 14 and bag filter lid 15, outer layer support frame 12, internal layer support frame 13, dialysis pkt. flap
The support construction for the bag filter 7 that son 14 and bag filter lid 15 form is that outer layer semi-permeable membrane 17 and internal layer semi-permeable membrane 16 provide jail
Solid basis, improve the safety and reliability of bag filter 7, the life cycle of bag filter 7 increases, and cost of dialysing and speed are equal
Improved.
As shown in Figure 1, the utility model further includes constant flow pump 5, constant flow pump 6, sample container 10 and dialysis fluid container 11, institute
Sample inlet pipe 1 and sample outlet pipe 2 that sample container 10 is equipped with connection bag filter 7 are stated, sample inlet pipe 1 is arranged in constant flow pump 5
On pipeline, the pumping samples liquid into bag filter 7, the dialysis fluid container 11 is equipped with 3 He of dialyzate outlet pipe of connection dialysate tank 8
Dialyzate inlet pipe 4, constant flow pump 6 are arranged on the pipeline of dialyzate inlet pipe 4, pump dialyzate into dialysate tank 8.Sample liquid and thoroughly
Analysis liquid is contained in respectively in sample container 10 and dialysis fluid container 11, respectively enters bag filter 7 and dialysate tank 8 by the effect of pump
Middle carry out convective flow, flow direction is as shown by arrows, and the effect of pump increases the osmotic pressure of semi-permeable membrane two sides, is completed at the same time certainly
Dynamic liquid feeding keeps device more convenient while promoting dialysis speed.
As shown in Figure 1, the upper end of the utility model dialysate tank 8 is equipped with dialysis can end 9, dialysis can end 9, which is equipped with, to be connect
Mouthful, respectively the interface of the interface of sample inlet pipe 1, the interface of sample outlet pipe 2 and dialyzate outlet pipe 3, sample inlet pipe 1 and sample go out
Pipe 2 passes through interface and submerges in dialysate tank 8, is connected on bag filter 7, is suspended in bag filter 7 in dialyzate, makes dialyzate and sample
Contact area between liquid is maximized, and dialysis speed improves.
In order to avoid occurring to enter pollutant in liquid splash and dialyzate in dialysis procedure, dialysate tank 8 top and
It is provided with seal washer between can end 9 of dialysing, ensure that the leakproofness of device.
The above is only the preferred embodiment of the utility model, not makees in any form to the utility model
Limitation, although the utility model has been disclosed with preferred embodiment as above, is not intended to limit the utility model, any to be familiar with
The technical staff of this patent is not departing within the scope of technical solutions of the utility model, when the technology contents work using above-mentioned prompt
A little equivalent embodiment changed or be modified to equivalent variations out, but all contents without departing from technical solutions of the utility model,
Any simple modification, equivalent change and modification made by the above technical examples according to the technical essence of the present invention, still belong to
In the range of the utility model.
Claims (9)
1. a kind of immediate dialysis device, including dialysate tank and bag filter, it is characterised in that: the bag filter is placed in dialysate tank,
Dialyzate is accommodated in dialysate tank, sample liquid is accommodated in bag filter, and the bag filter includes outer layer semi-permeable membrane and is recessed inwardly interior
Layer semi-permeable membrane, the dialyzate are flowed in the exterior space of outer layer semi-permeable membrane and internal layer semi-permeable membrane, and sample liquid is in outer layer semi-permeable membrane
Inner space flowing between internal layer semi-permeable membrane, the internal layer semi-permeable membrane of the bag filter are surrounded into perforative space, dialyzate from
One end of perforative space flows into, and flows out from the other end of perforative space and mixes with the dialyzate outside outer layer semi-permeable membrane.
2. a kind of immediate dialysis device according to claim 1, it is characterised in that: the bag filter includes playing a supportive role
Outer layer support frame and internal layer support frame, outer layer semi-permeable membrane is located on the outside of outer layer support frame, and internal layer semi-permeable membrane is located at internal layer and supports
On the outside of frame.
3. a kind of immediate dialysis device according to claim 1, it is characterised in that: the bag filter further includes being located at outer layer
The bag filter lid of support frame and internal layer support frame both ends.
4. a kind of immediate dialysis device according to claim 1, it is characterised in that: including constant flow pump, sample container and thoroughly
Analyse liquid container, the sample container and constant flow pump piping connection, constant flow pump and bag filter piping connection, the dialysis fluid container with
Constant flow pump piping connection, constant flow pump and dialysate tank piping connection.
5. a kind of immediate dialysis device according to claim 4, it is characterised in that: the bag filter two sides be equipped with sample into
Pipe and sample outlet pipe, constant flow pump are arranged on sample inlet pipe.
6. a kind of immediate dialysis device according to claim 4, it is characterised in that: the dialysate tank both ends are equipped with dialyzate
Inlet pipe and dialyzate outlet pipe, constant flow pump are arranged on dialyzate inlet pipe.
7. a kind of immediate dialysis device according to claim 4, it is characterised in that: the dialysate tank upper end is equipped with dialysate tank
End cap, end cap are equipped with interface, and the interface includes that dialyzate goes out interface tube, and sample inlet pipe interface and sample go out interface tube.
8. a kind of immediate dialysis device according to claim 7, it is characterised in that: including seal washer, the gasket
Circle is located between dialysis can end and dialysate tank.
9. a kind of immediate dialysis device according to claim 1, it is characterised in that: the bag filter by sample inlet pipe and
Sample outlet pipe is suspended in dialyzate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821955705.9U CN209333537U (en) | 2018-11-26 | 2018-11-26 | A kind of immediate dialysis device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821955705.9U CN209333537U (en) | 2018-11-26 | 2018-11-26 | A kind of immediate dialysis device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209333537U true CN209333537U (en) | 2019-09-03 |
Family
ID=67749154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821955705.9U Active CN209333537U (en) | 2018-11-26 | 2018-11-26 | A kind of immediate dialysis device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209333537U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111298650A (en) * | 2020-04-01 | 2020-06-19 | 谷昌德 | High-efficient dialysis medical treatment experimental facilities |
-
2018
- 2018-11-26 CN CN201821955705.9U patent/CN209333537U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111298650A (en) * | 2020-04-01 | 2020-06-19 | 谷昌德 | High-efficient dialysis medical treatment experimental facilities |
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