CN209269976U - A kind of mouse knot, rectum medicine applying apparatus - Google Patents
A kind of mouse knot, rectum medicine applying apparatus Download PDFInfo
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- CN209269976U CN209269976U CN201820585800.8U CN201820585800U CN209269976U CN 209269976 U CN209269976 U CN 209269976U CN 201820585800 U CN201820585800 U CN 201820585800U CN 209269976 U CN209269976 U CN 209269976U
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Abstract
The utility model relates to a kind of syringe accessory devices, more particularly to a kind of mouse knot, rectum medicine applying apparatus, belong to medical instruments field, including dosage control syringe and perfusion tube, dosage controls syringe and is made of screw rod core, dosage control nut, rubber plug, housing, spiral interface；Infusion apparatus is made of spiral interface, liquid-transport pipe-line, hollow out liquid-transport pipe-line；Dosage control nut is set on screw rod core, can be moved up and down by the screw thread of screw rod wicking surface；Screw rod wicking surface has volume scale；Screw rod core is connect with rubber plug, is pushed and is driven rubber plug to move in housing when screw rod core；Dosage syringe spiral interface is connect with infusion apparatus spiral interface.Big (small) mouse colon medical fluid is given using the present apparatus, has the characteristics that dosage is accurate, medical fluid is evenly distributed, anti-medical fluid flows back, operating efficiency is high；In addition, the present apparatus also has many advantages, such as that structure is simple, easy to operate, low manufacture cost.
Description
Technical field
The utility model relates to a kind of syringe accessory devices, and in particular to a kind of mouse knot, rectum medicine applying apparatus belong to doctor
Treat instrument field.
Background technique
Big (small) mouse intestinal canal administration is carried out using conventional syringe and common transfusion pipe in the prior art, it is ineffective.It is main
In terms of wanting defect to have following two:
1. dosage is inaccurate.
1. conventional syringe setting dosage marking line usually on syringe, by by the privileged site of piston rod core when use
It is directed at preset dosage marking line on syringe.But it is easily difficult to because the collimation errors such as looking up or overlooking by piston rod core when operating
It accurately is pushed into predetermined position, so that the demand being precisely administered is not able to satisfy, especially using rat, mouse as the science of research object
In research process, dosage is less (100 μ L or less), therefore conventional syringe pushes piston rod core privileged site and syringe
The error generated when upper dosage mark calibration can lead to the change of dosage, to influence the accuracy of scientific research.
2. conventional syringe is difficult to disposably be pushed into assigned scale during pushing piston rod core, easily lead to medicament
Amount front and back is different.
2. medical fluid is unevenly distributed and Yi Huiliu.
Use during pre-stage test common transfusion pipe to implement intestinal canal administration, because drug under syringe pressure instantaneously from defeated
The liquid pipe broken ends of fractured bone pours in enteron aisle, and medical fluid concentrates on a certain region of enteron aisle, causes local dose excessive；Or medical fluid exited with perfusion tube,
Enteron aisle anger is blamed and is flowed back, or even is overflow to outside anus, and medicine-feeding part inaccuracy, the phenomenon of dose deficiency is caused to occur.
3. low efficiency or liquid waste.
To guarantee the accurate of dosage, conventional syringe can only draw single administration amount, be unable to successive administration；To guarantee
Operating efficiency, conventional syringe can draw larger medicine amount liquid, but need to readjust scale after being administered, and cause liquid waste.
Utility model content
To solve drawbacks described above existing in the prior art, the utility model, which provides one kind, can be precisely controlled dosage,
And it can be effectively controlled equally distributed mouse knot, rectum medicine applying apparatus of the medical fluid in enteron aisle.
To achieve the goals above, the technical solution adopted in the utility model are as follows:
A kind of mouse knot, rectum medicine applying apparatus, including dosage control syringe and infusion apparatus, it is characterised in that: dosage control
Syringe is made of screw rod core, dosage control nut, rubber plug, housing, spiral interface；Infusion apparatus is by spiral interface, perfusion tube
Road, hollow out liquid-transport pipe-line composition；Dosage control nut is set on screw rod core, can be above and below the screw thread by screw rod wicking surface
It is mobile；Screw rod wicking surface has volume scale；Screw rod core is connect with rubber plug, drives rubber plug in housing when pushing screw rod core
It is mobile；Dosage syringe spiral interface is connect with infusion apparatus spiral interface；Infusion apparatus spiral interface, liquid-transport pipe-line, hollow out infusion
Pipeline sequence is arranged.
Dosage control nut is sheathed on the separate rubber plug end of screw rod core, and one end of screw rod core connects rubber plug, screw rod
The other end of core is far from rubber plug end.
The housing is the shell that dosage controls syringe, and screw rod core, rubber plug are respectively positioned in housing；Spiral interface position
In housing end.
Infusion apparatus spiral interface, liquid-transport pipe-line, building sky liquid-transport pipe-line are integrally formed, and total length is 150 mm, and internal diameter is
1.5 mm；Liquid-transport pipe-line, hollow out liquid-transport pipe-line wall thickness are 0.25 mm.
Hollow out liquid-transport pipe-line length is 10 mm；Hollow out liquid-transport pipe-line top is enclosed construction, hollow out liquid-transport pipe-line top table
Face is smooth, cambered.
Hollow out liquid-transport pipe-line surface has uniform hole, and hollow out liquid-transport pipe-line surface is other than hollow out liquid-transport pipe-line top
Region, 0.3 mm of hole diameter is spaced 0.3 mm between adjacent holes.
Screw rod core and rubber plug are using concave-convex connection type；Dosage control nut on screw rod wicking surface screw thread by moving down
The dynamic advance distance to adjust screw rod core.
Dosage syringe spiral interface can closely be connect with infusion apparatus spiral interface by screw thread.
Compared with the existing technology, the utility model has the following beneficial effects:
1) dosage control syringe middle dosage control nut accurately controls dosage, and when administration only need to firmly push spiral shell
Spinner handle core is until it cannot push, repetitively administered and dose deviations caused by can avoid because of the collimation error；It is firmly pushed when administration
Screw rod core can be such that medical fluid sprays from hollow out perfusion tube, and medical fluid distribution is more uniform.
2) for dosage control syringe dosage by dosage control nut control, minimum exact dose is 0.02 mL, is applicable in
It is accurately administered in rat, mouse intestinal.
3) spiral interface is used between dosage control syringe and liquid-transport pipe-line, connection is even closer, can prevent because energetically
Liquid-transport pipe-line caused by pressing screw bar core falls off or the phenomenon of leakage.
4) hollow out liquid-transport pipe-line end sealing and use hole design (0.3 mm of hole diameter, 0.3 mm of hole spacing),
Medical fluid can be made to be uniformly distributed in medicine-feeding part, avoid local dose excessive or insufficient and because medical fluid caused by when dosage is larger returns
Stream；Top is closed, smooth, cambered, can smoothly enter into experimental animal enteron aisle conducive to perfusion tube, avoids physical damnification, improves work
Efficiency.
5) device can once draw larger medicine amount liquid, realize that continuous several times are accurately administered using dosage control nut, have
The loss of medical fluid caused by effect is avoided calibrating repeatedly in more experimental animal administration process, is vented, improves injection efficiency, save at
This.
6) apparatus structure is simple, low in cost.
Detailed description of the invention
Fig. 1 is that dosage controls syringe planar structure schematic diagram；
Fig. 2 is perfusion tube planar structure schematic diagram；
Fig. 3 is hollow out liquid-transport pipe-line planar structure schematic diagram；
Fig. 4 is hollow out liquid-transport pipe-line stereoscopic schematic diagram；
Fig. 5 is the drug reflux schematic diagram of the medication of the device of convenient administration mode and use the utility model；
Fig. 6 is convenient administration mode and changes signal using the site of action of the medication of the device of the utility model
Figure.
Specific embodiment
Utility model will be further explained below with reference to the attached drawings and specific embodiments.
Referring to Fig. 1-4, a kind of mouse knot, rectum medicine applying apparatus control syringe (Fig. 1), perfusion tube (Fig. 2) two by dosage
Divide and constitutes.Dosage syringe is made of screw rod core 1, dosage control nut 2, rubber plug 3, housing 4,5 five part of spiral interface；It is defeated
Liquid device is made of spiral interface 6, liquid-transport pipe-line 7,8 three parts of hollow out liquid-transport pipe-line.
Dosage control nut 2 is set on screw rod core 1, can be moved up and down by the screw thread on 1 surface of screw rod core；Spiral
Bar wicking surface has volume scale, and minimum scale is 0.02 mL.
Screw rod core 1 and rubber plug 3 are pushed away using concave-convex connection type (i.e. the recessed portion of 1 one end of screw rod core insertion rubber plug)
Dynamic screw rod core 1 can drive rubber plug 3 to move in housing 4；Dosage control nut 2 on 1 surface screw thread of screw rod core by moving down
The advance distance of dynamic control screw rod core 1.
Dosage syringe spiral interface 5 can closely be connect with infusion apparatus spiral interface 6 by screw thread；Prevent slippage and liquid
Extravasation.
Infusion apparatus spiral interface 6, liquid-transport pipe-line 7, hollow out liquid-transport pipe-line 8 are integrated production, and total length is 150 mm, internal diameter
It is unanimously 1.5 mm；Liquid-transport pipe-line 7,8 wall thickness of hollow out liquid-transport pipe-line, 0.25 mm.
8 length of hollow out liquid-transport pipe-line is 10 mm；The top 9 of hollow out liquid-transport pipe-line 8 is enclosed construction, and surface is smooth, has arc
Degree.
10 diameter of surface hole defect, 0.3 mm of hollow out liquid-transport pipe-line is spaced 0.3 mm between hole.
Using the utility model device when, 1) dosage control nut 2 is sheathed on the separate rubber plug end of screw rod core 1,
Dosage control nut 2 is located on the outside of housing and is cased with certain distance with outer；Connection screw rod core 1 and rubber plug 3 are placed on housing 4
It is interior.2) lifting screw rod core 1 is drawn in certain medicine amount liquid to housing 4.3) by the spiral interface 5 of dosage control syringe and infusion
Device spiral interface 6 connects.4) push screw rod core 1 that medical fluid is made to enter liquid-transport pipe-line 7 and full of hollow out liquid-transport pipe-line 8.5) it adjusts
Dosage controls nut 2 to corresponding scale, and enforcing screw rod core 1 makes medical fluid overflow by liquid-transport pipe-line 7 from hollow out liquid-transport pipe-line 8
(screw rod core 1 is pushed to contact to dosage control nut 2 with housing 4, then can not push again) out.
The specific embodiment that the utility model is used for big (small) mouse intestinal canal administration is illustrated with reference to the accompanying drawing.
1. big (small) mouse after fasting is carried out calm or anesthesia according to test demand.
2. dosage syringe is connect after extracting appropriate medical fluid with perfusion tube, screw rod core is pushed to adequately fill up medical fluid
Perfusion tube, regulating dosage control nut to assigned scale.
3. lying on the back calm or postanesthetic big (small) mouse on experimental operation table, perfusion tube is slowly entered directly from anus
Intestines simultaneously soft are pushed into appointed part.
It is come into full contact with perfusion tube 4. fixing anal skin with hand, is enforced screw rod core and cannot extremely be pushed and is
Only；Perfusion tube is slowly withdrawn from enteron aisle after standing 1 min.
5. big (small) mouse is put back to mouse cage.
Remarks:
L perfusion tube uses medical silicone tube, and the material is tasteless to body, nontoxic, irritation is small；Cold-resistant, high temperature resistant, it is resistance to weak
Soda acid；Elasticity is good, resistance to kink is indeformable；Tube wall is smooth, is not easy the characteristics of adhering to, and is applicable to the administering medical liquids of Multiple components,
It is easy to wash, it can Reusability.
L is unsuitable for more sticky medical fluid because perfusion tube caliber and hollow out liquid-transport pipe-line hole aperture are small.
Test result analysis:
Applicant utilizes TNBS(trinitrobenzene sulfonic acid) big (small) mouse Ulcerative Colitis Model is prepared, discovery is originally practical new
Type modeling effect is substantially better than early period using conventional syringe and the modeling effect of perfusion tube.Early period is using conventional syringe and general
Easily there is medical fluid reflux in logical perfusion tube modeling, causes liquid dose not enough or medical fluid acts on non-designated position；Or medical fluid moment
Part is accumulated in, local dose is excessive and causes local damage excessively serious, it is difficult to reach good unified modeling effect.Using this
Utility model dosage is accurate, and medical fluid is evenly distributed, is not easy to flow back, and site of action is accurate, and modeling effect is preferable, grinds for science
The accuracy studied carefully provides guarantee.
It tests picture and compares explanation:
In Fig. 5, it is inaccurate to can lead to liquid dose deficiency, site of action for the easy backflow pollution crissum of convenient administration mode medical fluid
Really.In Fig. 5, medical fluid has no reflux after being administered using the utility model, and crissum is clean.
In Fig. 6, site of action changes after the reflux of convenient administration mode medical fluid, and major lesions position becomes rectum from colon,
And rectum position liquid volume causes greatly local organization hyperplasia, lesion serious, and enteron aisle is caused to be adhered, it is difficult to separate, not this research
The modeling effect of anticipation.Postcolon tissue obvious tumefaction, thickening are administered using the utility model, excrement intestine evacuation velocity is caused to drop
Low, enteron aisle stercoroma is the ideal modeling effect of this research.Fig. 6 additionally provides normal rat caecum, colon, rectum picture.
The utility model discloses a kind of for big (small) mouse knot, the device of rectum administering medical liquids comprising dosage control
Syringe, liquid-transport pipe-line two parts.It is demonstrated experimentally that big (small) mouse colon medical fluid is given using the present apparatus, the accurate, medicine with dosage
The feature that liquid is evenly distributed, anti-medical fluid flows back, operating efficiency is high；In addition, the present apparatus also have structure it is simple, it is easy to operate, system
Make the advantages such as cost is low, there is very strong practicability to the experimental study for carrying out big (small) mouse intestines problem.
The above is only the preferred embodiment of the utility model, it should be pointed out that: for the common skill of the art
For art personnel, without departing from the principle of this utility model, several improvements and modifications can also be made, these improve and
Retouching also should be regarded as the protection scope of the utility model.
Claims (4)
1. a kind of mouse knot, rectum medicine applying apparatus, including dosage control syringe and infusion apparatus, it is characterised in that: dosage control note
Emitter is made of screw rod core, dosage control nut, rubber plug, housing, spiral interface；Infusion apparatus by spiral interface, liquid-transport pipe-line,
Hollow out liquid-transport pipe-line composition；Dosage control nut is set on screw rod core, can be moved down on the screw thread by screw rod wicking surface
It is dynamic；Screw rod wicking surface has volume scale；Screw rod core is connect with rubber plug, is pushed and is driven rubber plug to move in housing when screw rod core
It is dynamic；Dosage syringe spiral interface is connect with infusion apparatus spiral interface；Infusion apparatus spiral interface, liquid-transport pipe-line, hollow out perfusion tube
Road sequence is arranged；Dosage control nut is sheathed on the separate rubber plug end of screw rod core, and one end of screw rod core connects rubber plug, spiral
The other end of bar core is far from rubber plug end；The housing is the shell that dosage controls syringe, and screw rod core, rubber plug are respectively positioned on
In housing；Spiral interface is located at housing end；Hollow out liquid-transport pipe-line surface has uniform hole, and hollow out liquid-transport pipe-line surface is
Region other than hollow out liquid-transport pipe-line top, 0.3 mm of hole diameter are spaced 0.3 mm between adjacent holes；Screw rod core and glue
Plug is using concave-convex connection type；Dosage control nut is moved up and down by screw rod wicking surface screw thread to adjust pushing away for screw rod core
Into distance；Hollow out liquid-transport pipe-line top is enclosed construction, and hollow out liquid-transport pipe-line top end surface is smooth, cambered；It need to be pushed away when administration
Press screw rod core until it cannot push.
2. a kind of mouse knot according to claim 1, rectum medicine applying apparatus, it is characterised in that: infusion apparatus spiral interface, infusion
Pipeline, building sky liquid-transport pipe-line are integrally formed, and total length is 150 mm, and internal diameter is 1.5 mm；Liquid-transport pipe-line, hollow out liquid-transport pipe-line
Wall thickness is 0.25 mm.
3. a kind of mouse knot according to claim 1, rectum medicine applying apparatus, which is characterized in that hollow out liquid-transport pipe-line length is
10 mm。
4. a kind of mouse knot according to claim 1, rectum medicine applying apparatus, which is characterized in that dosage syringe spiral interface
It is closely connect with infusion apparatus spiral interface by screw thread.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820585800.8U CN209269976U (en) | 2018-04-24 | 2018-04-24 | A kind of mouse knot, rectum medicine applying apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820585800.8U CN209269976U (en) | 2018-04-24 | 2018-04-24 | A kind of mouse knot, rectum medicine applying apparatus |
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| Publication Number | Publication Date |
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| CN209269976U true CN209269976U (en) | 2019-08-20 |
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ID=67597346
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| Application Number | Title | Priority Date | Filing Date |
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| CN201820585800.8U Active CN209269976U (en) | 2018-04-24 | 2018-04-24 | A kind of mouse knot, rectum medicine applying apparatus |
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| Country | Link |
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| CN (1) | CN209269976U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110897754A (en) * | 2019-12-13 | 2020-03-24 | 中国水产科学研究院黑龙江水产研究所 | Rainbow trout attacks poisonous syringe for experiment |
| CN113559352A (en) * | 2021-09-27 | 2021-10-29 | 时新(上海)产品设计有限公司 | Micro-dose output structure, micro-dose secretion pump and insulin pump |
-
2018
- 2018-04-24 CN CN201820585800.8U patent/CN209269976U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110897754A (en) * | 2019-12-13 | 2020-03-24 | 中国水产科学研究院黑龙江水产研究所 | Rainbow trout attacks poisonous syringe for experiment |
| CN113559352A (en) * | 2021-09-27 | 2021-10-29 | 时新(上海)产品设计有限公司 | Micro-dose output structure, micro-dose secretion pump and insulin pump |
| CN113559352B (en) * | 2021-09-27 | 2022-01-18 | 时新(上海)产品设计有限公司 | Micro-dose output structure, micro-dose secretion pump and insulin pump |
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