CN209252831U - A kind of burnt 3-D imaging system of skin copolymerization - Google Patents
A kind of burnt 3-D imaging system of skin copolymerization Download PDFInfo
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- CN209252831U CN209252831U CN201821383228.3U CN201821383228U CN209252831U CN 209252831 U CN209252831 U CN 209252831U CN 201821383228 U CN201821383228 U CN 201821383228U CN 209252831 U CN209252831 U CN 209252831U
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- galvanometer
- lens
- mirror
- imaging system
- mounting
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Abstract
The utility model discloses a kind of skins to be copolymerized burnt 3-D imaging system, including an infrared laser, one end of infrared laser is provided with X-direction high speed resonant, spectroscope is provided between infrared laser and X-direction high speed resonant, one condenser is installed in spectroscopical lower section, reflecting mirror is installed below condenser, Y direction galvanometer is installed below X-direction high speed resonant, image rotation group is provided on the horizontal position of Y direction galvanometer, the lens that image rotation group is oppositely arranged by two are constituted, object lens are installed in the side of image rotation group.The utility model passes through total focused light passages and reflecting mirror, focus excitation beam forms two-dimensional scanning light class in focussing plane, is collected simultaneously the optical path of return, confocal microscopic image can be neatly realized, influence of the vibration to conjugation in use process is eliminated, the using effect of product is improved.
Description
Technical field
The utility model relates to a kind of 3-D imaging systems more particularly to a kind of skin to be copolymerized burnt 3-D imaging system.
Background technique
The concept of confocal microscopy from eighties of last century the fifties by putting forward, through multidigit scholar to confocal imaging after
Finer research is carried out.More and more the microscope based on confocal principle is developed.But since computer is sent out
Horizontal restriction is opened up, just has the Laser Scanning Confocal Microscope really used appearance until the seventies, the mid-80 just has commodity type
It sells.With the development of computer image processing technology since the nineties, the advantages of confocal microscopy three-dimensional chromatography ability
Gradually show especially out.Compared with conventional microscope, with the especially longitudinal high-resolution of high-resolution and digital picture three
The characteristics of dimension chromatography, by the attention of more and more experts, be widely used in biomedicine, material science, micro-electronic manufacturing,
The detection and analysis in the fields such as accurate measurement.
Confocal microscope has the characteristics that the especially longitudinal high-resolution of high-resolution, allows its axial direction to sample
Optical chromatography is carried out, so as to reconstruct the 3-D image of sample.It breaches the limit of ordinary optical microscope diffraction limit
System, lateral resolution is 1.4 times of the ordinary optical microscope of identical numerical aperture.Longitudinal resolution can achieve sub-micron
Grade, therefore axial chromatography can be carried out to thick biological sample.
Since the 1980s, there are several research group's report confocal scanning microscopes to the thin of humans and animals
Born of the same parents and nucleus details imaging in vivo.And ratio, traditional histological biopsy include tissue cutting in contrast, and it is fixed, it cuts thin
The processes such as piece, dyeing, therefore, tissue biopsy have intrusive mood, and pain has wound to check point, stays scar, and is difficult to accurately
The disadvantages of positioning specifically needs check point.In some surgical operations, such as the basal-cell carcinoma surgical procedure that Moh is provided,
Histological section (edge for determining tumour) need to be carried out in operating room.Under normal circumstances, it needs to cut 2-4 piece, per a piece of tissue
Processing needs 15-45 minutes.In conclusion tissue biopsy is clinically both time-consuming and expensive diagnostic mode.Copolymerization
Burnt flying-spot microscope is then not necessarily to the waiting of such time-consuming, and can provide the real-time diagnostic imaging of non-intruding to doctor.
With the development of more than ten years in past, the skin iconography detection method based on body surface includes dermoscopy, skin ultrasound
Etc. being rapidly developed.Wherein dermoscopy can only check skin lesion surface, helpless for deep skin structure；Skin
Although skin ultrasound can detect deep skin structure, its image resolution ratio is lower, cannot be judged according to its ultrasonogram
The Infiltrating extrent that is good pernicious and determining skin lesion of skin neoplasin, inspection result is also vulnerable to the position of patient, the pressure etc. of probe
Many factors influence.Peeping microscopical image definition in copolymerization coke commonly used in the prior art based on image-carrying fiber bundle has
Limit, and be in honeycomb, be unfavorable for observing, and due to micro scanning reflecting mirror be it is mechanical, speed is slower, and image taking speed is about 3
Frame/second, far below the video frame rate (24 frames/second) of current mainstream, realtime graphic can have appreciable Caton, and image meeting
It is thickened due to shake, the prior art is no longer satisfied the requirement of people, has yet to be improved and developed.
Utility model content
The purpose of this utility model is to provide a kind of skins to be copolymerized burnt 3-D imaging system, solves of the existing technology
Shortcoming.
The utility model adopts the following technical solution realizes:
A kind of skin is copolymerized burnt 3-D imaging system, which is characterized in that including an infrared laser, infrared laser
One end is provided with X-direction high speed resonant, is provided with spectroscope between infrared laser and X-direction high speed resonant,
One condenser is installed in spectroscopical lower section, a reflecting mirror is installed below the condenser, described
It is provided with aperture and photodetector in the horizontal direction of reflecting mirror, Y-axis side is installed below X-direction high speed resonant
To galvanometer, image rotation group is provided on the horizontal position of the Y direction galvanometer, the image rotation group is oppositely arranged saturating by two
Mirror is constituted, and is equipped with object lens in the side of image rotation group.
Further, which further includes a laser mounting assembly, and the laser mounting assembly passes through peace
It fills seat to be arranged on optical adjusting frame, is provided with light modulation frame mounting blocks and lens on the optical adjusting frame, lens and thoroughly
Mirror installs block assembly and is connected, and galvanometer mounting framework is provided in the middle part of imaging system, is equipped with galvanometer on galvanometer mounting framework
Motor is connected with Z-axis transmission component and Z axis connecting tube in one end of galvanometer mounting framework, and the upper surface of galvanometer mounting framework connects
It is connected to mirror outer cylinder flange connector and the outer drum flange of mirror, one end of the Z-axis transmission component is provided with Z axis aggregation mirror assembly, institute
It states and lens assembly is installed on Z axis aggregation mirror assembly, detector mounting plate is installed at the rear of optical adjusting frame.
The advantageous effects of the utility model are: by total focused light passages and reflecting mirror, focus excitation beam is being focused
Plane forms two-dimensional scanning light class, is collected simultaneously the optical path of return, confocal microscopic image can be neatly realized, eliminating makes
With the influence vibrated in the process to conjugation, the using effect of product is improved.
Detailed description of the invention
Fig. 1 is the light path principle figure that skin is copolymerized burnt 3-D imaging system.
Fig. 2 is the mechanical structure exploded view that skin is copolymerized burnt 3-D imaging system.
Fig. 3 is the mechanical structure assembling figure that skin is copolymerized burnt 3-D imaging system.
Fig. 4 is the mechanical structure assembling figure at another visual angle Fig. 3.
Specific embodiment
By the following description of the embodiment, public understanding the utility model will more be facilitated, but can't should
Specific embodiment given by applicant is considered as the limitation to technical solutions of the utility model, any pair of component or technology are special
The definition of sign be changed and/or to overall structure make form and immaterial convert the technology of the utility model of being regarded as
Protection scope defined by scheme.
Description of symbols: laser mounting assembly 1, galvanometer mounting framework 2, lens installation block assembly 3, mounting rack 4,
APD plate L shape link block 5, APD plate link block 6, Z-axis transmission component 7, Z axis focus mirror assembly 8, Z axis connecting tube 9, nikon lens
10, galvanometer 11, galvanometer motor 12, lens 13, male and fomale(M&F) 14,15,45 degree of mounting bases 16 of photodiode mounting plate, light modulation frame peace
Fill the outer drum flange 20 of block 17, optical adjusting frame 18, APD flange 19, mirror, mirror outer cylinder flange connector 21, lens assembly 22, outside mirror
Drum flange connector 23, hexagon socket cap head screw 24, hexagon socket cap head screw 25, hexagon socket cap head screw 26, cross
Slot sunk screw 27
As shown in Figure 1, the burnt 3-D imaging system of skin copolymerization, including an infrared laser A, the one of infrared laser A
End is provided with X-direction high speed resonant C, is provided with spectroscope between infrared laser A and X-direction high speed resonant C
B is equipped with a condenser H below spectroscope B, a reflecting mirror I is equipped with below condenser H, in reflecting mirror I
Horizontal direction on be provided with aperture and photodetector G, be equipped with below X-direction high speed resonant C Y direction vibration
Mirror D is provided with image rotation group E on the horizontal position of Y direction galvanometer D, and the lens that image rotation group E is oppositely arranged by two are constituted,
Object lens F is installed in the side of image rotation group.
Such as Fig. 2, it further includes a laser mounting assembly 1, laser mounting assembly 1 that skin, which is copolymerized burnt 3-D imaging system,
It is arranged on optical adjusting frame 18 by mounting base, light modulation frame mounting blocks 17 and lens, lens is provided on optical adjusting frame 18
It is connected with lens installation block assembly 3, galvanometer mounting framework 2 is provided in the middle part of imaging system, is installed on galvanometer mounting framework 2
There is galvanometer motor 12, is connected with Z-axis transmission component 7 and Z axis connecting tube 9, galvanometer mounting framework in one end of galvanometer mounting framework 2
2 upper surface is connected with mirror outer cylinder flange connector 21 and the outer drum flange 20 of mirror, and it is poly- that one end of Z-axis transmission component 7 is provided with Z axis
Collect mirror assembly 8, lens assembly 22 is installed on Z axis aggregation mirror assembly 8, two pole of photoelectricity is installed at the rear of optical adjusting frame 18
Pipe mounting plate 15.
Working principle: laser source system provides laser light source for entire microscope, and light beam is realized by spectroscope and is divided
Purpose, substitute traditional Amici prism.Laser beam is coupled light according to different control signals by galvanometer at different angles
Beam, the effect of object lens are to focus to the laser of imaging beam outgoing on human skin tissue.
Laser source system provide laser light source pass through fiber coupler, into galvanometer scanning unit after be emitted, pass through
Scanning lens couples, by objective lens exit to human skin tissue；Laser irradiation generates anti-after human skin tissue
It penetrates, reflected light passes through object lens, lens, galvanometer again, is transmitted in optical detection system, and optical detection system converts optical signal into telecommunications
Number, and realize digital-to-analogue conversion, the digital signal of reflected light is obtained, digital signal passes through image analysis and reconstruct system in host again
System completes image reconstruction, and then shows on the visual interface.In the present embodiment, optical detection system includes lens, light letter
Number detection and amplifying device, detection skin generate reflected light signal under the irradiation of laser.This optical signal is burnt by object lens, copolymerization
Scanning element, optical signal detection and amplifying device, are finally converted to electric signal by optical detector.Meanwhile 3-D imaging system is also
It can be connected with each other with the same image analysis and reconfiguration system, the collected single point signals of optical detection system are reduced into two dimension
Or three-dimensional image, the fine structure of detected sample is reappeared, such as the eucaryotic cell structure of human skin tissue.
Laser is equipped with inside laser mounting assembly 1, which drives sending laser to be visited by laser driver
It surveys, laser enters in galvanometer after projecting through lens.In galvanometer scanning unit, incident laser is first through vibration mirror reflected, then
It is transmitted from lens, is incident on other galvanometers, using other vibration mirror reflecteds, is then incident on lens.Incident laser light
Beam is coupled by lens, using being incident on skin histology after being transmitted to object lens.Laser irradiation produces after skin histology
Raw reflected light signal is transmitted from object lens first, then by being transferred back into the laser of laser mounting assembly 1, most
Collected single point signals are reduced into two dimension or three-dimensional image at last, reappear the eucaryotic cell structure of detected tissue.
The present embodiment can reduce the physical size of object lens end under the precondition for improving image resolution, increase instrument
The operating flexibility of device improves its application range and image quality.Overcome prior art confocal scanning micro-endoscope
The not high disadvantage of heavy inflexible and image quality is operated, probe physics high with flexibly operability, image resolution ratio
The small various technical effects of size.
Certainly, the utility model can also have other various embodiments, without departing substantially from the spirit of the present invention and its essence
In the case where, those skilled in the art can make various corresponding changes and modifications, but this according to the utility model
A little corresponding changes and modifications all should belong to the protection scope of the utility model the attached claims.
Claims (2)
1. a kind of skin is copolymerized burnt 3-D imaging system, which is characterized in that including an infrared laser, the one of infrared laser
End is provided with X-direction high speed resonant, is provided with spectroscope between infrared laser and X-direction high speed resonant,
Spectroscopical lower section is equipped with a condenser, and a reflecting mirror is equipped with below the condenser, described anti-
It penetrates in the horizontal direction of mirror and is provided with aperture and photodetector, Y direction is installed below X-direction high speed resonant
Galvanometer is provided with image rotation group, the lens that the image rotation group is oppositely arranged by two on the horizontal position of the Y direction galvanometer
It constitutes, object lens is installed in the side of image rotation group.
2. skin according to claim 1 is copolymerized burnt 3-D imaging system, which is characterized in that the imaging system further includes one
A laser mounting assembly, the laser mounting assembly are arranged on optical adjusting frame by mounting base, the pH effect
Light modulation frame mounting blocks and lens are provided on frame, the lens are connected with lens installation block assembly, set in the middle part of imaging system
It is equipped with galvanometer mounting framework, galvanometer motor is installed on galvanometer mounting framework, Z axis is connected in one end of galvanometer mounting framework and passes
Dynamic component and Z axis connecting tube, the upper surface of galvanometer mounting framework is connected with mirror outer cylinder flange connector and the outer drum flange of mirror, described
One end of Z-axis transmission component is provided with Z axis aggregation mirror assembly, lens assembly is equipped on the Z axis aggregation mirror assembly, in optics
The rear of adjustment frame is equipped with detector mounting plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821383228.3U CN209252831U (en) | 2018-08-27 | 2018-08-27 | A kind of burnt 3-D imaging system of skin copolymerization |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821383228.3U CN209252831U (en) | 2018-08-27 | 2018-08-27 | A kind of burnt 3-D imaging system of skin copolymerization |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209252831U true CN209252831U (en) | 2019-08-16 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821383228.3U Expired - Fee Related CN209252831U (en) | 2018-08-27 | 2018-08-27 | A kind of burnt 3-D imaging system of skin copolymerization |
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| CN (1) | CN209252831U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113679346A (en) * | 2021-08-24 | 2021-11-23 | 吉林亚泰中科医疗器械工程技术研究院股份有限公司 | Adjustable working distance and can be used for assisting confocal microscope's skin mirror |
-
2018
- 2018-08-27 CN CN201821383228.3U patent/CN209252831U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113679346A (en) * | 2021-08-24 | 2021-11-23 | 吉林亚泰中科医疗器械工程技术研究院股份有限公司 | Adjustable working distance and can be used for assisting confocal microscope's skin mirror |
| CN113679346B (en) * | 2021-08-24 | 2023-08-22 | 吉林亚泰中科医疗器械工程技术研究院股份有限公司 | Skin mirror capable of adjusting working distance and used for auxiliary confocal microscope |
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Granted publication date: 20190816 Termination date: 20210827 |
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| CF01 | Termination of patent right due to non-payment of annual fee |