CN209237422U - A kind of high-pressure column chromatography extraction element - Google Patents

A kind of high-pressure column chromatography extraction element Download PDF

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Publication number
CN209237422U
CN209237422U CN201821836871.7U CN201821836871U CN209237422U CN 209237422 U CN209237422 U CN 209237422U CN 201821836871 U CN201821836871 U CN 201821836871U CN 209237422 U CN209237422 U CN 209237422U
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China
Prior art keywords
block
silica gel
ring
column
gel preparation
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Application number
CN201821836871.7U
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Chinese (zh)
Inventor
王若研
史跃满
陈晓彤
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YUANDA PHARMACEUTICAL CO Ltd DALIAN
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YUANDA PHARMACEUTICAL CO Ltd DALIAN
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Priority to CN201821836871.7U priority Critical patent/CN209237422U/en
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Abstract

The utility model discloses a kind of high-pressure columns to chromatograph extraction element, including pedestal, the base top is provided with hydraulic lift, connection ring is provided at the top of the hydraulic lift, the connection ring bottom is provided with discharge nozzle, silicagel column is provided at the top of the connection ring, silica gel preparation column is provided at the top of the silicagel column, silica gel preparation column top is provided with joint mechanism, silica gel preparation column top is provided with link block, it is provided with fixed ring block at the top of the link block, fixed ring block both ends are provided with snap ring.The utility model is by being equipped with joint mechanism, link block, fixed ring block and discharge nozzle, make the utility model in use, silica gel preparation column can be made to be easily changed, and it can be discharged at once in purification & isolation rear impurity, this remain in impurity will not in equipment, silicagel column is set to keep clean, to keep the service life of silicagel column longer.

Description

A kind of high-pressure column chromatography extraction element
Technical field
The utility model relates to extraction element technical field, in particular to a kind of high-pressure column chromatographs extraction element.
Background technique
Chromatography extraction element is a kind of equipment that can be rejected impurity, needs to use when handling silica gel this Equipment, chromatography extraction element in the prior art in use, divide since silica gel preparation column is not easy to replace, and in purification It will not be discharged at once from rear impurity, this just makes impurity be easy to remain in equipment, so that silicagel column is cannot keep cleaning, to make The service life of silicagel column is shorter.
Therefore, it is necessary to solve the above problems to invent a kind of high-pressure column chromatography extraction element.
Utility model content
The purpose of this utility model is to provide a kind of high-pressure columns to chromatograph extraction element, by being equipped with joint mechanism, connection Block, fixed ring block and discharge nozzle, make the utility model in use, and silica gel preparation column can be made to be easily changed, and Purification & isolation rear impurity can be discharged at once, this remain in impurity will not in equipment, and silicagel column is allow to keep clean, To keep the service life of silicagel column longer, to solve the problems mentioned in the above background technology.
To achieve the above object, the utility model provides the following technical solutions: a kind of high-pressure column chromatography extraction element, including Pedestal, the base top are provided with hydraulic lift, are provided with connection ring, the connection at the top of the hydraulic lift Ring bottom is provided with discharge nozzle, and silicagel column is provided at the top of the connection ring, is provided with silica gel preparation column at the top of the silicagel column, Silica gel preparation column top is provided with joint mechanism, and silica gel preparation column top is provided with link block, the link block top Portion is provided with fixed ring block, and fixed ring block both ends are provided with snap ring, and peristaltic pump connection is provided at the top of the fixed ring block Pipe, the peristaltic pump connecting tube are fixedly connected with fixed ring block, and peristaltic pump connecting tube one end is provided with peristaltic pump, described compacted Dynamic pump connecting tube side is provided with feed pipe.
Preferably, the joint mechanism includes joint ring, and the joint ring outer wall is provided with screw thread, the joint ring outside It is provided with link slot.
Preferably, the joint ring outer wall and link slot inner wall are provided with screw thread, and the link slot is arranged in link block It is internal.
Preferably, the joint ring and link block are threadedly coupled, and the fixed ring block is slidably connected with link block.
Preferably, described discharge nozzle one end is fixedly connected with silica gel preparation column, and the setting of fixed ring block bottom is connecting Inside slot.
Preferably, the base top is provided with support rod, and the base bottom is provided with anti-skidding bed course.
The technical effect and advantage of the utility model:
1, by being equipped with joint mechanism, link block, fixed ring block and discharge nozzle, after purified on silica gel can be made to separate, impurity It can be discharged immediately, when silica gel preparation column is replaced using a period of time, connector can be made by Rotary Connection block Ring rotates in link slot, and silica gel preparation column and link block is facilitated to be separated or connected, this is just using the utility model In the process, silica gel preparation column can be made to be easily changed, and can be discharged at once in purification & isolation rear impurity, this just makes impurity It will not remain in equipment, so that silicagel column is kept clean, to keep the service life of silicagel column longer;
2, by being equipped with support rod, it can play a supporting role to equipment, prevent hydraulic lift because of top apparatus mistake It damages again, by being equipped with anti-skidding bed course, can make equipment on the ground can not arbitrarily be slided, so that equipment be allow to keep steady Fixed work.
Detailed description of the invention
Fig. 1 is the overall structure diagram of the utility model.
Fig. 2 is the overall structure side view of the utility model.
Fig. 3 is the portion A enlarged drawing in Fig. 1 of the utility model.
In figure: 1 pedestal, 2 hydraulic lifts, 3 connection rings, 4 discharge nozzles, 5 silicagel columns, 6 silica gel preparation columns, 7 splicers Structure, 8 link blocks, 9 fixed ring blocks, 10 snap rings, 11 peristaltic pump connecting tubes, 12 peristaltic pumps, 13 feed pipes, 14 joint rings, 15 screw threads, 16 link slots, 17 support rods.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work Every other embodiment obtained, fall within the protection scope of the utility model.
The utility model provides a kind of high-pressure column chromatography extraction element as shown in Figs. 1-3, including pedestal 1, the bottom 1 top of seat is provided with hydraulic lift 2, and connection ring 3,3 bottom of connection ring are provided at the top of the hydraulic lift 2 It is provided with discharge nozzle 4, silicagel column 5 is provided at the top of the connection ring 3, silica gel preparation column 6 is provided at the top of the silicagel column 5, It is provided with joint mechanism 7 at the top of the silica gel preparation column 6, is provided with link block 8, the connection at the top of the silica gel preparation column 6 Fixed ring block 9 is provided at the top of block 8,9 both ends of fixed ring block are provided with snap ring 10, are provided at the top of the fixed ring block 9 Peristaltic pump connecting tube 11, the peristaltic pump connecting tube 11 are fixedly connected with fixed ring block 9, and described 11 one end of peristaltic pump connecting tube is set It is equipped with peristaltic pump 12,11 side of peristaltic pump connecting tube is provided with feed pipe 13.
Further, in the above-mentioned technical solutions, the joint mechanism 7 includes joint ring 14,14 outer wall of joint ring It is provided with screw thread 15, is provided with link slot 16 on the outside of the joint ring 14, joint ring 14 and link block 8 is allow to carry out screw thread company It connects, facilitates the replacement of silica gel preparation column 6.
Further, in the above-mentioned technical solutions, 14 outer wall of joint ring and 16 inner wall of link slot are provided with screw thread 15, it is threadedly coupled joint ring 14 and link block 8, the link slot 16 is arranged inside link block 8, can pass through Joint ring 14 is inserted into link slot 16, connect link block 8 with silica gel preparation column 6.
Further, in the above-mentioned technical solutions, the joint ring 14 and link block 8 are threadedly coupled, and facilitate silica gel preparation The replacement of column 6, the fixed ring block 9 are slidably connected with link block 8, make link block 8 when rotating on joint ring 14, link block 8 It can be along 9 upward sliding of fixed ring block.
Further, in the above-mentioned technical solutions, described 4 one end of discharge nozzle is fixedly connected with silica gel preparation column 6, makes silica gel After purification & isolation, impurity can be discharged immediately, and 9 bottom of fixed ring block is arranged inside link slot 16, make silica gel preparation column 6 In replacement process, snap ring 10 can block link block 8, fall down link block 8 will not from fixed ring block 9.
Further, in the above-mentioned technical solutions, it is provided with support rod 17 at the top of the pedestal 1, equipment can be played Supporting role prevents hydraulic lift 2 from damaging because top apparatus is overweight, and 1 bottom of pedestal is provided with anti-skidding bed course, can So that equipment can not be slided arbitrarily on the ground, so that equipment be allow to keep steady operation.
This practical working principle:
Referring to Figure of description 1-3, when handling using the utility model silica gel, start peristaltic pump 12 first, Peristaltic pump connecting tube 11 is set to keep the state of persistent pressure, this can be constantly pre- to silica gel by the silica gel in feed pipe 13 Addition in standby column 6, silica gel preparation column 6 can be handled silica gel, separate silica gel and impurity, and separation rear impurity can enter discharging Pipe 4, after separating purified on silica gel, impurity can be discharged immediately, when silica gel preparation column 6 is after a period of use with regard to needing to carry out more It changes, since joint ring 14 and link block 8 are threadedly coupled, Rotary Connection block 8 can be moved by manpower, connect joint ring 14 can Rotation in slot 16, so that link block 8 can be separated with joint ring 14, after separation after making link block 8 rotate a period of time To remove silica gel preparation column 6, then new silica gel preparation column 6 is placed on the suitable position of connection ring 3, after the completion of placement Silica gel preparation column 6 is located at the underface of link block 8, by moving down link block 8, makes new 6 top of silica gel preparation column Joint ring 14 is inserted into link slot 16, then Rotary Connection block 8, and new silica gel preparation column 6 is made to be connected with link block 8, from And the replacement of silica gel preparation column 6 is completed, this just makes the utility model in use, and silica gel preparation column 6 can be made to be easy to more It changes, and can be discharged at once in purification & isolation rear impurity, this remain in impurity will not in equipment, make silicagel column 5 can To keep clean, to keep the service life of silicagel column 5 longer;
Referring to Figure of description 1-2, when the utility model is used, by being equipped with support rod 17, equipment can be played Supporting role prevents hydraulic lift 2 from damaging because top apparatus is overweight, by being equipped with anti-skidding bed course, equipment can be made to exist It can not arbitrarily be slided on ground, so that equipment be allow to keep steady operation.
Finally, it should be noted that the above descriptions are merely preferred embodiments of the present invention, it is not limited to this Utility model, although the utility model is described in detail with reference to the foregoing embodiments, for those skilled in the art For, it is still possible to modify the technical solutions described in the foregoing embodiments, or to part of technical characteristic It is equivalently replaced, within the spirit and principle of the utility model, any modification, equivalent replacement, improvement and so on, It should be included within the scope of protection of this utility model.

Claims (6)

1. a kind of high-pressure column chromatographs extraction element, including pedestal (1), it is characterised in that: be provided at the top of the pedestal (1) hydraulic Lifting device (2), hydraulic lift (2) top are provided with connection ring (3), and connection ring (3) bottom is provided with out Expects pipe (4), connection ring (3) top are provided with silicagel column (5), are provided with silica gel preparation column at the top of the silicagel column (5) (6), it is provided with joint mechanism (7) at the top of the silica gel preparation column (6), is provided with link block at the top of the silica gel preparation column (6) (8), it is provided with fixed ring block (9) at the top of the link block (8), fixed ring block (9) both ends are provided with snap ring (10), described It is provided with peristaltic pump connecting tube (11) at the top of fixed ring block (9), the peristaltic pump connecting tube (11) and fixed ring block (9) fixed company Connect, described peristaltic pump connecting tube (11) one end is provided with peristaltic pump (12), peristaltic pump connecting tube (11) side be provided with into Expects pipe (13).
2. a kind of high-pressure column according to claim 1 chromatographs extraction element, it is characterised in that: joint mechanism (7) packet It includes joint ring (14), joint ring (14) outer wall is provided with screw thread (15), is provided with link slot on the outside of the joint ring (14) (16)。
3. a kind of high-pressure column according to claim 2 chromatographs extraction element, it is characterised in that: joint ring (14) outer wall It is provided with screw thread (15) with link slot (16) inner wall, link slot (16) setting is internal in link block (8).
4. a kind of high-pressure column according to claim 3 chromatographs extraction element, it is characterised in that: the joint ring (14) and company Block (8) threaded connection is connect, the fixed ring block (9) is slidably connected with link block (8).
5. a kind of high-pressure column according to claim 4 chromatographs extraction element, it is characterised in that: described discharge nozzle (4) one end It is fixedly connected with silica gel preparation column (6), fixed ring block (9) the bottom setting is internal in link slot (16).
6. a kind of high-pressure column according to claim 1 chromatographs extraction element, it is characterised in that: set at the top of the pedestal (1) It is equipped with support rod (17), pedestal (1) bottom is provided with anti-skidding bed course.
CN201821836871.7U 2018-11-08 2018-11-08 A kind of high-pressure column chromatography extraction element Active CN209237422U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201821836871.7U CN209237422U (en) 2018-11-08 2018-11-08 A kind of high-pressure column chromatography extraction element

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201821836871.7U CN209237422U (en) 2018-11-08 2018-11-08 A kind of high-pressure column chromatography extraction element

Publications (1)

Publication Number Publication Date
CN209237422U true CN209237422U (en) 2019-08-13

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115999198A (en) * 2023-03-27 2023-04-25 石药集团百克(山东)生物制药股份有限公司 Column chromatography equipment

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115999198A (en) * 2023-03-27 2023-04-25 石药集团百克(山东)生物制药股份有限公司 Column chromatography equipment

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