CN209139381U - A kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector - Google Patents

A kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector Download PDF

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Publication number
CN209139381U
CN209139381U CN201821748017.5U CN201821748017U CN209139381U CN 209139381 U CN209139381 U CN 209139381U CN 201821748017 U CN201821748017 U CN 201821748017U CN 209139381 U CN209139381 U CN 209139381U
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China
Prior art keywords
sample introduction
cleaning
needle
spring
overflow
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CN201821748017.5U
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Chinese (zh)
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江川
杨学军
郭秋阳
张志林
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Chengdu Ke Rui Technology Co Ltd
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Chengdu Ke Rui Technology Co Ltd
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Abstract

The utility model discloses a kind of sample introduction needle wiper mechanisms for liquid chromatograph sample injector, belong to sample introduction cleaning technique field, including pedestal and cleaning column, mounting bracket is provided on the pedestal, the sliding of the side longitudinal direction of the mounting bracket is provided with cleaning column, the cleaning chamber for cleaning sample introduction needle is equipped in the cleaning column, the lower end outer wall of the cleaning column is equipped with the inlet being connected to cleaning chamber;The bottom of the cleaning column is provided with needle seal assembly, and the apocenosis passage communicated with cleaning chamber is equipped with inside the upper end of the needle seal assembly, and apocenosis passage is connected to the exhaust chamber inside needle seal assembly lower end;The bottom of the needle seal assembly is connected with sample introduction pressure detecting assembly by spring assembly.The sample introduction pressure that the utility model can enter cleaning column to sample introduction needle is accurately controlled, and is avoided damaging sample introduction needle, and cleaning solution effectively can be discharged by way of upper and lower drain, is improved cleaning efficiency, needle sealing effect is good, practical and convenient.

Description

A kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector
Technical field
The utility model relates to sample introduction cleaning technique fields, are a kind of for liquid chromatograph sample injector specifically Sample introduction needle wiper mechanism.
Background technique
Chromatograph, for the device for carrying out chromatographic isolation analysis.At sampling system, detection system, record and data Reason system, temperature control system and mobile phase control system etc..Modern chromatograph have stability, sensitivity, versatility and from The features such as dynamicization degree is high.There are gas chromatograph, liquid chromatograph and gel permeation chrommatograph etc..These being widely used for of chromatograph Product, the analysis of certain content of high molecular material are learned, gel chromatography can also measure the molecular weight of high molecular material and its divide Cloth.In liquid chromatograph use process, need cleaning to sample introduction needle, in existing sample introduction needle wiper mechanism into Sample introduction pressure can not get a more precise control when sample needle is sent into cleaning column, and in the buffer function of not buffer gear Under, certain damage can be caused to sample introduction needle, influence using;The cleaning solution of sample introduction needle can not be preferable in cleaning column simultaneously Discharge, expulsion efficiency is low, and sealing effect is poor, so that the cleaning efficiency of cleaning sample introduction needle reduces.
Utility model content
Utility model aims to solve the above technical problem, provide it is a kind of for liquid chromatograph sample injector into Sample needle wiper mechanism, the sample introduction pressure that cleaning column can be entered to sample introduction needle are accurately controlled, avoid causing to damage to sample introduction needle It is bad, and cleaning solution can be effectively discharged by way of upper and lower drain, cleaning efficiency is provided, needle sealing effect is good, real With conveniently.
The utility model is achieved through the following technical solutions:
A kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector, including pedestal and cleaning column, on the pedestal It is provided with mounting bracket, the sliding of the side longitudinal direction of the mounting bracket is provided with cleaning column, is equipped with and is used in the cleaning column The cleaning chamber of sample introduction needle is cleaned, the lower end outer wall of the cleaning column is equipped with the inlet being connected to cleaning chamber;The cleaning column Bottom be provided with needle seal assembly, the apocenosis passage communicated with cleaning chamber, institute are equipped with inside the upper end of the needle seal assembly Apocenosis passage is stated to be connected to the exhaust chamber inside needle seal assembly lower end;The bottom of the needle seal assembly is connected by spring assembly It is connected to sample introduction pressure detecting assembly, the sample introduction pressure detecting assembly is set on the base.
In order to preferably realize the utility model, further, the spring assembly includes spring support, spring mounting cup And the bottom of needle seal assembly is arranged in spring, the spring support, the spring mounting cup is arranged on pressure detecting assembly, One end of the spring is arranged in spring mounting cup, and the other end of the spring is connect with spring support.
In order to preferably realize the utility model, further, the pressure detecting assembly includes pressure sensor, described Pressure sensor is set on the base by cushion block, and the spring mounting cup is arranged on pressure sensor.
In order to preferably realize the utility model, further, the top of the mounting bracket is equipped with overflow assemblies, described Overflow collection component includes overflow cup, covers the cup lid being located in overflow cup and mounting bracket is arranged in far from cleaning column side Sewer pipe, the bottom both ends of the overflow cup are respectively equipped with and the cleaning interconnecting piece that connect of top end and what is extended downwardly lead Pipe, is equipped with the overflow ducts being connected to cleaning chamber in the interconnecting piece, the overflow ducts and conduit with the inside of overflow cup Space is connected;Sewer pipe is provided on pedestal below the conduit.
In order to preferably realize the utility model, further, institute's overflow cup bottom is equipped with from interconnecting piece to conduit down Inclined guide part.
In order to preferably realize the utility model, further, the one end of the inlet far from cleaning chamber is threaded hole, It is connected to pressure screw in the threaded hole, inlet tube, the outlet end and inlet of the inlet tube are connected in the pressure screw Connection.
It further include shell further to preferably realize the utility model, the shell is located at the side of cleaning column It offers vertical sliding slot, limited block is fixed with by sunk screw between the two sides of the sliding slot;The pressure screw it is remote One end from cleaning column extends to the underface of limited block by sliding slot.
In order to preferably realize that the utility model, the conduit and sewer pipe of the overflow assemblies are respectively positioned on outside shell.
The utility model compared with prior art, have the following advantages that and the utility model has the advantages that
(1) the utility model is by being arranged needle seal assembly, spring assembly and sample introduction pressure in the bottom that cleaning column is arranged in Power detection components can be buffered after sample introduction needle is sent into cleaning column by punch block by spring assembly, while spring assembly Sample introduction pressure can be passed to sample introduction pressure detecting assembly, sample introduction pressure can be examined by sample introduction pressure detecting assembly It surveys to judge whether sample introduction needle continues to be fed into, realizes that sample introduction needle can accurately be sent into cleaning column and carry out inside and outside wall cleaning, avoid Sample introduction pressure is excessive or too small and the problem of cause sample introduction needle to be sent into not in place, sample introduction needle damage, it is practical and convenient.
(2) the utility model can prevent cleaning solution from sealing from needle by the way that needle seal assembly is arranged in the bottom of cleaning column Assembly leaks on sample introduction pressure detecting assembly, influences the numerical value of sample introduction pressure detecting;And by being set in needle seal assembly Apocenosis passage and exhaust chamber are set, is entered in exhaust chamber convenient for cleaning solution by flushing channel, then the row by being connected to exhaust chamber Liquid pipe discharge, while being matched with overflow collection component, the drain efficiency and cleaning efficiency of raising.
(3) by setting overflow collection component, the mode that cleaning solution is capable of overflow is discharged the utility model from cleaning column, And is entered in sewer pipe by overflow cup and be collected;The waste liquid that the setting of overflow cup and cup lid can be avoided overflow seeps everywhere Stream, ensure that the cleannes of wiper mechanism.
(4) the utility model promotes to clean what column moved down in punch block revocation by setting pressure screw and limited block After active force, cleaning column under the action of the spring can be popped up, and can be limited cleaning column by setting limited block and be continued up It is mobile, so that cleaning column is returned to initial position, structure is simple, practical.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model;
Fig. 2 is the limited block of the utility model and the positional diagram of pressure screw.
Wherein: 1- pedestal;2- mounting bracket;3- cleans column;4- cleans chamber;5- inlet;6- needle seal assembly;7- drain Chamber;8- spring support;9- spring;10- spring mounting cup;11- pressure sensor;12- cushion block;13- threaded hole;14- limited block; 15- shell;16- interconnecting piece;17- cup lid;18- overflow cup;19- conduit;20- sewer pipe;21- pressure screw.
Specific embodiment
In conjunction with shown in attached drawing 1, a kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector, including pedestal 1 and clear Column 3 to be washed, mounting bracket 2 is provided on the pedestal 1, the sliding of the side longitudinal direction of the mounting bracket 2 is provided with cleaning column 3, The cleaning chamber 4 for cleaning sample introduction needle is equipped in the cleaning column 3, the lower end outer wall of the cleaning column 3 is equipped with and cleaning chamber 4 The inlet 5 of connection;The bottom of the cleaning column 3 is provided with needle seal assembly 6, sets inside the upper end of the needle seal assembly 6 There is the apocenosis passage communicated with cleaning chamber 4, the apocenosis passage is connected to the exhaust chamber 7 inside 6 lower end of needle seal assembly;It is described The bottom of needle seal assembly 6 is connected with sample introduction pressure detecting assembly, the sample introduction pressure detecting assembly setting by spring assembly On pedestal 1.
The feeding of sample introduction needle is realized by the punch block of sample injector;The cleaning column 3 for being slidably arranged in mounting bracket 2 can Moving up and down for longitudinal direction is carried out, buffering is able to carry out by matching for 9 component of spring, sample introduction needle is avoided to enter cleaning chamber 4 Hard contact behind bottom end and damage, while the downward sample introduction pressure of punch block can be passed to sample introduction pressure by 9 component of spring Power detection components detect sample introduction pressure by sample introduction pressure detecting assembly, and the sample introduction pressure value transmission that will test To the control system of sample injector, interpretation is carried out to the sample introduction pressure value that detection obtains by control system, if reach sample introduction pressure It is specified vertical, when reaching the rating number of sample introduction pressure, control system, which sends order to punch block, stops punch block to sample introduction The feeding of needle acts, and a feeding mode in this way can be accurately controlled sample introduction pressure, avoid sample introduction pressure Damage that is excessive and causing sample introduction needle or sample introduction pressure are too small and be sent into problem not in place, improve the feeding efficiency of sample introduction needle It is practical and convenient with feeding precision;After sample introduction needle is admitted in place, cleaning solution is inputted to sample introduction to cleaning chamber 4 by inlet 5 The outer wall of needle is cleaned, and the waste liquid after cleaning flows into exhaust chamber 7 by the apocenosis passage of needle seal assembly 6, by with drain The drain pipe discharge that chamber 7 is connected to, the cleaning for inner wall is to be conveyed cleaning solution by peristaltic pump, and pass through six-way valve Mutually its internal cleaning injected cleaning solution, realize to needle inner wall at the top of from sample introduction needle, and the waste liquid after cleaning is from followed by needle Apocenosis passage, the exhaust chamber 7 of seal assembly 6 are discharged, to realize the cleaning to the inside and outside wall of sample introduction needle;6 energy of needle seal assembly It enough prevents cleaning solution from leaking on sample introduction pressure detecting assembly from needle seal assembly 6, influences the numerical value of sample introduction pressure detecting.
Further, as the preferred of different embodiments, the spring assembly includes spring support 8, spring mounting cup 10 With spring 9, the bottom of needle seal assembly 6 is arranged in the spring support 8, and the spring mounting cup 10 is arranged in pressure detecting group On part, one end of the spring 9 is arranged in spring mounting cup 10, and the other end of the spring 9 is connect with spring support 8.
Spring support 8 is fixed on the bottom of needle seal assembly 6, and its bottom end stretches to the inside of spring 9, and spring branch The outside of frame 8 may be a fixed connection with spring 9 to be also possible to abut;Spring 9 is fixed on spring far from one end of spring support 8 The bottom of the inside of mounting cup 10, the internal diameter of spring mounting cup 10 are greater than the outer diameter of needle seal assembly 6, so both can be to from needle The waste liquid that seal assembly 6 leaks is collected, and avoids leakage on sample introduction pressure detecting assembly, and can prevent spring 9 from pressing The lower axial dipole field generated of power effect, improves the stability of sample introduction.
Further, as the preferred of different embodiments, the pressure detecting assembly includes pressure sensor 11, the pressure Force snesor 11 is arranged on pedestal 1 by cushion block 12, and the spring mounting cup 10 is arranged on pressure sensor 11.
Pressure sensor 11 is used to detect sample introduction pressure, and by the control system of sample introduction pressure transmission to sample injector, by controlling The pressure value that system processed detects pressure sensor 11 is handled and is judged.
Further, as the preferred of different embodiments, the top of the mounting bracket 2 is equipped with overflow assemblies, described to overflow Stream collection assembly includes overflow cup 18, covers the cup lid 17 being located in overflow cup 18 and setting in mounting bracket 1 far from cleaning column 3 The sewer pipe 20 of side, the bottom both ends of the overflow cup 18 be respectively equipped with the cleaning interconnecting piece 16 that connect of 3 top of column and The conduit 19 extended downwardly, the interconnecting piece 16 is interior to be equipped with the overflow ducts being connected to cleaning chamber 4, the overflow ducts and conduit 19 are connected with the inner space of overflow cup 18;Sewer pipe 20 is provided on the pedestal 1 of 19 lower section of conduit.
The interconnecting piece 16 of overflow cup 18 is that transition fit is connect so that it is convenient to which overflow cup 18 is torn open with the top of cleaning column 3 Dress, cup lid 17 are equipped with the opening passed through for sample introduction needle;Overflow ducts in the interconnecting piece 16 of overflow cup 18 are clear with cleaning column 3 4 top of chamber is washed to match correspondence, for sample introduction needle pass through and the overflow of waste liquid;It cleans clear to the inside and outside wall of sample introduction needle in chamber 4 Waste liquid a part after washing overflows spill cavity by way of overflow, and into overflow cup 18, the waste liquid in overflow cup 18 is then It is flowed by conduit 19 in the sewer pipe 20 of lower section, waste liquid is collected by sewer pipe 20;The bottom of sewer pipe 20 also The drain pipe connection of channel equipped with drain, channel and 1 bottom of pedestal being connected to, is excluded, structure is simple, real convenient for waste liquid With conveniently.
Further, as the preferred of different embodiments, 18 bottom of institute's overflow cup is equipped with past from interconnecting piece 16 to conduit 19 Under inclined guide part.
Guide part is set by 18 bottom of overflow cup between interconnecting piece 16 and conduit 19, overflow enters overflow cup 18 Waste liquid can preferably can be flowed into sewer pipe 20 by conduit 19 under the guiding role of guide part.
Further, as the preferred of different embodiments, the one end of the inlet 5 far from cleaning chamber 4 is threaded hole 13, Be connected to pressure screw 21 in the threaded hole 13, be connected to inlet tube in the pressure screw 21, the outlet end of the inlet tube with Inlet 5 connects.
After compression bolts screw in screw thread mouth, internal inlet tube is stretched in inlet 5, and the cleaning solution in inlet tube It is then flowed into cleaning chamber 4 by inlet 5, realizes the injection of cleaning solution;The setting of pressure screw 21 is convenient for carrying out inlet tube It fixes and to being sealed on the outside of inlet 5, cleaning solution is avoided to ooze out.
It further, further include shell 15 as the preferred of different embodiments, the shell 15 is located at the one of cleaning column 3 Side offers vertical sliding slot, is fixed with limited block 14 by sunk screw between the two sides of the sliding slot;The pressure screw One end of 21 separate cleaning column 3 extends to the underface of limited block 14 by sliding slot.
As shown in Fig. 2, promoting cleaning column 3 to move down in punch block revocation by setting pressure screw 21 and limited block 14 Active force after, under the action of spring 9 clean column 3 can pop up, by be arranged limited block 14 can limit cleaning column 3 after It is continuous to move up, so that cleaning column 3 is returned to initial position, structure is simple, practical.
Further, as the preferred of different embodiments, the conduit 19 and sewer pipe 20 of the overflow assemblies are respectively positioned on outer Outside shell 15.
By being arranged sewer pipe 20 outside shell 15, convenient for the dismounting and cleaning to sewer pipe 20.
Working principle of the utility model is:
After sample injector completes primary sample, punch block drives sample introduction needle to move down, and sample introduction needle passes sequentially through overflow cup 18 Lid 17 and overflow cup 18, into the cleaning chamber 4 of cleaning column 3, after being continuously fed to and sample introduction needle being made to enter needle seal assembly 6, Spring 9 is compressed under the sample introduction pressure effect that punch block applies, and is passed to sample introduction pressure by spring 9, spring mounting cup 10 On pressure sensor 11, obtained pressure is detected to pressure sensor 11 by the control system of sample injector and carries out processing judgement, When sample introduction pressure value reaches specified sample introduction pressure value, control system control punch block stopping continues to move down, will by peristaltic pump Cleaning solution is conveyed by inlet tube, flows through pressure screw 21 and by opening in the cleaning chamber 4 of the injection cleaning column 3 of inlet 5 Beginning cleans the outer wall of sample introduction needle;After control system gets the instruction cleaned to sample introduction needle inner wall, by compacted Dynamic pump, six-way valve will carry out inner wall washing in the inner wall of cleaning solution injection sample introduction needle;And waste liquid a part after cleaning is by overflowing The mode of stream enters in overflow cup 18, is collected by sewer pipe 20, another part by the apocenosis passage of needle seal assembly 6, Exhaust chamber 7 is discharged;After the cleaning for completing sample introduction needle, punch block is moved up, and waits the sample introduction needle cleaning command of next time.
The above is only the preferred embodiment of the utility model, not does limit in any form to the utility model System, any simple modification made by the above technical examples according to the technical essence of the present invention, equivalent variations, each falls within Within the protection scope of the utility model.

Claims (8)

1. a kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector, including pedestal (1) and cleaning column (3), feature It is, be provided with mounting bracket (2) on the pedestal (1), the sliding of the side longitudinal direction of the mounting bracket (2) is provided with cleaning Column (3), is equipped with cleaning chamber (4) for cleaning sample introduction needle in cleaning column (3), on the lower end outer wall of cleaning column (3) Equipped with the inlet (5) being connected to cleaning chamber (4);The bottom of cleaning column (3) is provided with needle seal assembly (6), the needle The apocenosis passage communicated with cleaning chamber (4), the apocenosis passage and needle seal assembly are equipped with inside the upper end of seal assembly (6) (6) exhaust chamber inside lower end (7) is connected to;The bottom of the needle seal assembly (6) is connected with sample introduction pressure by spring assembly Detection components, the sample introduction pressure detecting assembly are arranged on pedestal (1).
2. a kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector according to claim 1, it is characterised in that: The spring assembly includes spring support (8), spring mounting cup (10) and spring (9), and spring support (8) setting is close in needle The bottom of assembly (6) is sealed, the spring mounting cup (10) is arranged on pressure detecting assembly, and one end of the spring (9) is arranged In spring mounting cup (10), the other end of the spring (9) is connect with spring support (8).
3. a kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector according to claim 2, it is characterised in that: The pressure detecting assembly includes pressure sensor (11), and the pressure sensor (11) is arranged by cushion block (12) in pedestal (1) on, the spring mounting cup (10) is arranged on pressure sensor (11).
4. a kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector according to claim 1, it is characterised in that: The top of the mounting bracket (2) be equipped with overflow assemblies, the overflow collection component include overflow cup (18), lid be located at overflow cup (18) cup lid (17) and setting on are in the sewer pipe (20) of mounting bracket (2) far from cleaning column (3) side, the overflow cup (18) bottom both ends are respectively equipped with the interconnecting piece (16) connecting with cleaning column (3) top and the conduit (19) extended downwardly, It is equipped with the overflow ducts being connected to cleaning chamber (4) in the interconnecting piece (16), the overflow ducts and conduit (19) are and overflow The inner space of cup (18) is connected;Sewer pipe (20) are provided on pedestal (1) below the conduit (19).
5. a kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector according to claim 4, it is characterised in that: Institute's overflow cup (18) bottom is equipped with from interconnecting piece (16) to conduit (19) inclined guide part down.
6. a kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector according to claim 4, it is characterised in that: The one end of the inlet (5) far from cleaning chamber (4) is threaded hole (13), is connected to pressure screw in the threaded hole (13) (21), it is connected to inlet tube in the pressure screw (21), the outlet end of the inlet tube is connect with inlet (5).
7. a kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector according to claim 6, it is characterised in that: It further include shell (15), the side that the shell (15) is located at cleaning column (3) offers vertical sliding slot, the two sides of the sliding slot Between limited block (14) is fixed with by sunk screw;One end of the separate cleaning column (3) of the pressure screw (21) passes through cunning Slot extends to the underface of limited block (14).
8. a kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector according to claim 7, it is characterised in that: The conduit (19) and sewer pipe (20) of the overflow assemblies are respectively positioned on shell (15) outside.
CN201821748017.5U 2018-10-26 2018-10-26 A kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector Active CN209139381U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201821748017.5U CN209139381U (en) 2018-10-26 2018-10-26 A kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201821748017.5U CN209139381U (en) 2018-10-26 2018-10-26 A kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector

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Publication Number Publication Date
CN209139381U true CN209139381U (en) 2019-07-23

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CN201821748017.5U Active CN209139381U (en) 2018-10-26 2018-10-26 A kind of sample introduction needle wiper mechanism for liquid chromatograph sample injector

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111961589A (en) * 2020-08-12 2020-11-20 江苏信安佳医疗科技有限公司 Automatic liquid changing device for three-dimensional organoid sphere culture

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111961589A (en) * 2020-08-12 2020-11-20 江苏信安佳医疗科技有限公司 Automatic liquid changing device for three-dimensional organoid sphere culture
CN111961589B (en) * 2020-08-12 2023-10-31 江苏信安佳医疗科技有限公司 Automatic liquid changing device for three-dimensional organoid sphere culture

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