CN209075828U - A kind of nasal sinus targeted delivery of drugs device based on 3D printing - Google Patents

A kind of nasal sinus targeted delivery of drugs device based on 3D printing Download PDF

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Publication number
CN209075828U
CN209075828U CN201821699588.4U CN201821699588U CN209075828U CN 209075828 U CN209075828 U CN 209075828U CN 201821699588 U CN201821699588 U CN 201821699588U CN 209075828 U CN209075828 U CN 209075828U
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China
Prior art keywords
nasal sinus
targeted delivery
grug transportation
drugs device
medicine
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CN201821699588.4U
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Chinese (zh)
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康凌航
康柱
郑力铭
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Xi'an Jiweike Intelligent Technology Co ltd
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Shaanxi Hengtong Intelligent Machine Co Ltd
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Abstract

The utility model relates to field of medical article technology, and in particular to a kind of nasal sinus targeted delivery of drugs device based on 3D printing.The nasal sinus targeted delivery of drugs device of the utility model nose type bracket and delivery catheter by being made of;The nose type bracket and nostril corresponding position are provided with cylindrical tube;The delivery catheter is made of grug transportation tube and medicine-pouring pipe, and the two is fixedly connected;The grug transportation tube is internally provided with the partition for playing atomizing far from medicine-pouring pipe one end;The grug transportation tube of the delivery catheter can be inserted into cooperating therewith in cylindrical tube.The utility model product is easy to use and can orient uniformity of dosage, improves patient's compliance, reduces medication stimulation.And the problems such as period for solving traditional diamond-making technique is long, and hardly possible is processed.

Description

A kind of nasal sinus targeted delivery of drugs device based on 3D printing
Technical field
The utility model relates to field of medical article technology, specifically, being that a kind of nasal sinus based on 3D printing is directed to Medicine device.
Background technique
Nasosinusitis is the nonspecific inflammation of sinus mucosa, is a kind of rhinology common frdquently encountered disease.Patient shows as chilly more Fever, the whole body are uncomfortable, lassitude, apply be intended to decline, a variety of symptoms such as rhinostegnosis, dense tears, seriously affect patients ' life quality.
Mainly have for the treatment method of nasosinusitis at present: oral drugs, operative treatment, rhinitis aerosol, phinamide Deng.When using rhinitis aerosol, main by being directed at the method directly sprayed in nostril administration, this kind of method causes largely patient Drug waste, and drug cannot accurately reach nasal sinus position, cannot achieve precisely administration and uniformity of dosage.And nose drops makes With needing that correct application method, such as head is cooperated to extend back a dripping method, head downside to position dripping method, it just can guarantee that drug reaches Diseased region plays therapeutic effect.
Prior art CN207520443U discloses a kind of nasal cavity medicine applicator, including medication tube, and drug bottom of the tube is fixed to be connected It is connected to medicament canister connector, is uniformly provided with multiple medicine outlet holes on medication tube top and side wall.The nasal cavity medicine applicator can be accurately Drug is applied into entire nasal cavity, and there is no administration dead angle, ensure that the uniformity of administration.But the structure is only applicable in In the uniformity of dosage of entire nasal cavity, fixed point administration can not achieve.
The prior art can be realized the device of orientation uniformity of dosage it is still necessary to a kind of easy to use.
Utility model content
In view of the defects existing in the prior art, the utility model provides a kind of orientation nasal sinus administration based on 3D printing Device, it is easy to use and uniformity of dosage can be oriented, improve patient's compliance.Specifically, the particular technique side of the utility model Case are as follows:
A kind of nasal sinus targeted delivery of drugs device based on 3D printing, is made of nose type bracket and delivery catheter;The nose type bracket Nostril corresponding position is provided with cylindrical tube;The delivery catheter is made of grug transportation tube and medicine-pouring pipe, and the two is fixedly connected;It is described Grug transportation tube is internally provided with the partition for playing atomizing far from medicine-pouring pipe one end;The grug transportation tube of the delivery catheter can be inserted into circle It is cooperating therewith in column tube.
Further, the overall diameter of the grug transportation tube is 1.5-2.5mm;The overall diameter of the medicine-pouring pipe is straight outside grug transportation tube 2-5 times of diameter.
Further, the internal diameter of the grug transportation tube is 0.1-0.3mm.
Further, the partition is diamond shape, and apart from grug transportation tube outlet, distance is 2-8mm.Diamond shape partition can guarantee medicine Object is effectively atomized, and dose is suitable for out.
Further, internal screw thread is provided in the cylindrical tube, one end setting that the grug transportation tube is connect with medicine-pouring pipe There is the external screw thread matched with internal screw thread.The two cooperates, it can be achieved that according to the nasal sinus position of different patients, adjusts grug transportation tube The distance of nasal sinus is exported to, to efficiently use drug, does not cause drug waste.
Further, nose type supporting piece position corresponding with the bridge of the nose is provided with protrusion.Hand is used during being easy to use It helps, in case nose type supporting piece is not fixed firmly and leans on.
Further, at least 2 circle screw threads are provided in the medicine-pouring pipe.The setting of screw thread, convenient in administration process with give The fixation of medicine bottle.
Further, the nose type supporting piece is integrally formed using 3D printing technique.Since nasal cavity part is curvature portion, pass Uniting, the processing method period is long, and hardly possible processing can effectively solve the inconvenience of traditional processing using 3D printing technique.
Further, the material of the nasal sinus targeted delivery of drugs device is photosensitive resin, stainless steel or titanium.
The nasal sinus targeted delivery of drugs device based on 3D printing is printed with the following method, and main includes obtaining medicine Iconography data, the threedimensional model for generating nasal sinus targeted delivery of drugs device, printing manufacture nasal sinus targeted delivery of drugs device.
Further, the acquisition Medical Imaging data the following steps are included:
Instrument title: Artec Eva handheld three-dimensional scanner;
Patient facial region is scanned using handheld three-dimensional scanner to obtain patient facial region's data.
Further, the process for generating nasal sinus site-specific delivery of drugs device threedimensional model includes:
1, the three-dimensional data of STL format is exported by scanning obtained patient facial region's data;
2, data processing reparation then is carried out with Geomagic Wrap2017 software export the STL formatted data handled well;
3, it recycles CATIAV5R20 software to import the data repaired above and carries out reverse modeling, exported after completing modeling STL the or STP format that can be printed;
4,21.0 software of Materialise Magics is recycled to carry out the operation of data modification and printing support.
The utility model has the following beneficial effects: (1) targeted delivery of drugs compared with the existing technology, reduces drug waste;(2) Drug is atomized at nasal sinus, directly acts on nasal sinus;(3) easy to use;(4) adjustable defeated according to the needs of different patients Pencil mouth to nasal sinus distance;(5) medication stimulation is small, and patient's compliance is high.
Detailed description of the invention
Fig. 1: the utility model targeted delivery of drugs device nose type bracket;
Fig. 2: the utility model targeted delivery of drugs device delivery catheter;
Fig. 3: the utility model targeted delivery of drugs device right view;
Fig. 4: the utility model targeted delivery of drugs device A to sectional view enlarged drawing;
Number representative structure is as follows in figure:
1, nose type bracket;2, raised;3, cylindrical tube;4, internal screw thread;5, grug transportation tube;6, medicine-pouring pipe;7, external screw thread;8, spiral shell Line;9, grug transportation tube exports;10, partition.
Specific embodiment
Below in conjunction with specific embodiment, the technical solution of the utility model is described further.Art technology Personnel should be appreciated that the utility model embodiment is only used for the explanation to technical solutions of the utility model, should not constitute pair The limitation of scope of protection of the utility model.Any change or equivalent replacement made based on the utility model thought, should all fall into Scope of protection of the utility model.
Embodiment 1
A kind of nasal sinus targeted delivery of drugs device based on 3D printing, is made of nose type bracket 1 and delivery catheter, nose type bracket 1 with There are two cylindrical tubes 3 for the setting of nostril corresponding position.Delivery catheter is two, and the delivery catheter is by medicine-pouring pipe 6 and grug transportation tube 5 It constitutes.The interior diameter of the cylindrical tube 3 is identical as the overall diameter of grug transportation tube 5, and the two cooperates.Grug transportation tube 5 is apart from loading The partition for playing atomizing is provided at pipe outlet 2-8mm.
The Method of printing of above-mentioned nasal sinus targeted delivery of drugs device are as follows: patient facial region's three-dimensional data is obtained by scanner;By three-dimensional Data construct threedimensional model;According to three dimensional model printing nasal sinus targeted delivery of drugs device.
In use process, patient wears nose type bracket first, and delivery catheter passes through the cylindrical tube 3 of nose type bracket 1, and with Cylindrical tube is fixed;Medicine bottle is engaged by the screw thread 8 of injection pipe internal surface with delivery catheter, and drug is sprayed through medicine bottle, passes through note The nozzle of pencil and grug transportation tube interface enters grug transportation tube, until being atomized at the partition of grug transportation tube front end, and exports and sprays through grug transportation tube Out, stepless action is in nasal sinus.
Embodiment 2
A kind of nasal sinus targeted delivery of drugs device based on 3D printing, the difference relative to embodiment 1 are: nose type bracket 1 with The corresponding position of the bridge of the nose is provided with protrusion 2, the support during being easy to use to delivery device.Remaining is the same as embodiment 1.
Embodiment 3
A kind of nasal sinus targeted delivery of drugs device based on 3D printing, the difference relative to embodiment 1 are: the round tube 3 It is inside provided with internal screw thread 4, one end that grug transportation tube 5 is connect with medicine-pouring pipe 6 is provided with the external screw thread 7 matched with internal screw thread 4, the two It cooperates, the distance that loading nozzle 9 arrives nasal sinus can be adjusted according to patient facial region's data information of scanning.Remaining same embodiment 1。
Embodiment 4
With reference to Fig. 1-4, a kind of nasal sinus targeted delivery of drugs device based on 3D printing is made of, nose nose type bracket 1 and delivery catheter There are two cylindrical tubes 3 for type bracket 1 and the setting of nostril corresponding position.Delivery catheter is two, and the delivery catheter is by medicine-pouring pipe 6 It is constituted with grug transportation tube 5.The length of perfusion tube 5 is 1-8cm, preferably 4cm.The interior diameter of the cylindrical tube 3 and grug transportation tube 5 Overall diameter is identical, and the two cooperates.And internal screw thread 4 is provided in the cylindrical tube 3, the grug transportation tube 5 connects with medicine-pouring pipe 6 The one end connect is provided with the external screw thread 7 matched with internal screw thread.
The outer radius of grug transportation tube 5 is 1.5-2.5mm, preferably 2mm.The outer radius of the medicine-pouring pipe 6 is half outside grug transportation tube 5 2-5 times of diameter, preferably 2.5 times.The inside radius of the grug transportation tube 5 is 0.1-0.3mm, preferably 0.2mm.5 distance of grug transportation tube The partition 10 for playing atomizing is provided at 2-8mm at grug transportation tube outlet 9.The partition 10 can for triangle, square, One of rectangle, irregular shape, diamond shape, preferably diamond shape.
Preferably, the nose type bracket 1 position corresponding with the bridge of the nose is provided with protrusion 2, helps during being easy to use Nose type bracket.Particularly, as long as phase same-action can be played in use, reach same effect, not to raised shape It is particularly limited to.
Preferably, screw thread, preferably 2 circles are provided in the medicine-pouring pipe 6.
Preferably, the nose type bracket 1 and delivery catheter are all made of 3D printing technique integrated molding.
The nasal sinus targeted delivery of drugs device is using one of photosensitive resin, stainless steel or titanium, preferably photosensitive resin.
The Method of printing of above-mentioned nasal sinus targeted delivery of drugs device are as follows: patient facial region's three-dimensional data is obtained by scanner;By three-dimensional Data construct threedimensional model;According to three dimensional model printing nasal sinus targeted delivery of drugs device.

Claims (9)

1. a kind of nasal sinus targeted delivery of drugs device based on 3D printing, it is characterised in that: be made of nose type bracket (1) and delivery catheter; The nose type bracket (1) and nostril corresponding position are provided with cylindrical tube (3);The delivery catheter is by grug transportation tube (5) and medicine-pouring pipe (6) it forms, the two is fixedly connected;The grug transportation tube (5) is internally provided with the partition for playing atomizing far from medicine-pouring pipe one end (10);The grug transportation tube (5) of the delivery catheter can be inserted into cooperating therewith in cylindrical tube (3).
2. nasal sinus targeted delivery of drugs device according to claim 1, it is characterised in that: the outer radius of the grug transportation tube (5) is 1.5-2.5mm;The outer radius of the medicine-pouring pipe (6) is 2-5 times of grug transportation tube (5) outer radius.
3. nasal sinus targeted delivery of drugs device according to claim 1, it is characterised in that: the inside radius of the grug transportation tube (5) is 0.1-0.3mm。
4. nasal sinus targeted delivery of drugs device according to claim 1, it is characterised in that: the partition (10) is diamond shape, apart from defeated It is 2-8mm that pencil, which exports (9) distance,.
5. -4 any nasal sinus targeted delivery of drugs device according to claim 1, it is characterised in that: setting in the cylindrical tube (3) Have internal screw thread (4), one end that the grug transportation tube (5) connect with medicine-pouring pipe (6) is provided with the external screw thread matched with internal screw thread (7)。
6. nasal sinus targeted delivery of drugs device according to claim 1, it is characterised in that: the nose type bracket (1) is opposite with the bridge of the nose The position answered is provided with raised (2).
7. nasal sinus targeted delivery of drugs device according to claim 1, it is characterised in that: be provided at least 2 in the medicine-pouring pipe (6) It encloses screw thread (8).
8. nasal sinus targeted delivery of drugs device according to claim 1, it is characterised in that: the nose type bracket uses 3D printing technique It is integrally formed.
9. nasal sinus targeted delivery of drugs device according to claim 1, it is characterised in that: the material of the nasal sinus targeted delivery of drugs device is Photosensitive resin, stainless steel or titanium.
CN201821699588.4U 2018-10-19 2018-10-19 A kind of nasal sinus targeted delivery of drugs device based on 3D printing Active CN209075828U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201821699588.4U CN209075828U (en) 2018-10-19 2018-10-19 A kind of nasal sinus targeted delivery of drugs device based on 3D printing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201821699588.4U CN209075828U (en) 2018-10-19 2018-10-19 A kind of nasal sinus targeted delivery of drugs device based on 3D printing

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111068168A (en) * 2018-10-19 2020-04-28 陕西恒通智能机器有限公司 3D printing-based nasal sinus directional drug delivery device and printing method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111068168A (en) * 2018-10-19 2020-04-28 陕西恒通智能机器有限公司 3D printing-based nasal sinus directional drug delivery device and printing method thereof

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Effective date of registration: 20220729

Address after: 710116 A225, floor 2, building a, collaborative innovation port R & D office building, Hongguang Avenue, Fengdong new town, Xi'an, Shaanxi Province

Patentee after: Xi'an jiweike Intelligent Technology Co.,Ltd.

Address before: 710054 south building, West fifth floor, Jiaotong University Science Park, No. 99, Yanxiang Road, Yanta District, Xi'an, Shaanxi Province

Patentee before: SHAANXI HENGTONG INTELLIGENT MACHINE Co.,Ltd.