CN209020293U - A kind of process units for the hemostasis-coagulation biological glue promoting wound mucosa regeneration - Google Patents

A kind of process units for the hemostasis-coagulation biological glue promoting wound mucosa regeneration Download PDF

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Publication number
CN209020293U
CN209020293U CN201821326292.8U CN201821326292U CN209020293U CN 209020293 U CN209020293 U CN 209020293U CN 201821326292 U CN201821326292 U CN 201821326292U CN 209020293 U CN209020293 U CN 209020293U
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bottle
support frame
hemostasis
process units
dissolution
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陈明远
邹雄
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Sun Yat Sen University Cancer Center
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陈明远
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Abstract

The utility model discloses a kind of process units of hemostasis-coagulation biological glue for promoting wound mucosa regeneration, it include: support frame, support frame as described above includes support frame upper layer and support frame lower layer, support frame as described above upper layer is equipped at least two solution bottles, support frame as described above lower layer is equipped with the dissolution bottle being used cooperatively with solution bottle, the water outlet of the solution bottle is connected to the water inlet of the dissolution bottle, and the water outlet of the solution bottle is equipped with flow control valve.Glue production device provided by the utility model is designed by its structure, can be effectively reduced occupied area and convenient glue production, be reduced production cost.Dissolution bottle in the device, it is provided with temperature sensor, circular spiral heat conducting pipe is installed in autoclave body, cooperate hot and cold medium tube that can be needed to adjust the intracorporal temperature of kettle at any time according to processing, and it is heated evenly material, improves the quality of glue, and is provided with flowmeter, scientific cold and hot medium can be mixed, to reach the temperature of demand.

Description

A kind of process units for the hemostasis-coagulation biological glue promoting wound mucosa regeneration
Technical field
The utility model relates to a kind of process units of biological glue, especially a kind of to promote the only solidifying of wound mucosa regeneration The process units of blood biological glue.
Background technique
Factor is usually mixed in corresponding solution respectively with fibrinogen, is generated respectively by biological glue Then when in use fibrin ferment and fibrin mix fibrin ferment and fibrin, but factor and fibrinogen It then needs to participate in reacting with room temperature when needing subzero 20 DEG C of low-temperature storages, and reacting with the dissolution of other solution, therefore biological glue Process units need flexibly to regulate and control temperature.
In addition, two-component glue needs are stirred according to processing compound, and require to produce in whipping process Otherwise anger bubble has bubble point on the surface of composite membrane and generates, not only influenced product quality but also increased rejection rate.It is in the prior art Agitating device includes a stirring rod and an agitator.Wherein, agitator is fixed, and stirring rod rotation simultaneously carries out composite glue It stirs and evenly mixs.However such agitating device is at work, since stirring rod will form vortex during operation and be mixed with sky Gas, to generate bubble;If mixing speed is faster, mixed bubble is more, if mixing speed is slower, agitating device Efficiency it is lower.It can be seen that the prior art requires further improvement.
Utility model content
It, can the purpose of the utility model is to overcome a kind of temperature is provided in place of above-mentioned the deficiencies in the prior art based on this It adjusts, the process units of the hemostasis-coagulation biological glue of the promotion wound mucosa regeneration of high production efficiency.
To achieve the above object, technical solution adopted in the utility model are as follows: a kind of to promote stopping for wound mucosa regeneration The process units of blood coagulation biological glue, comprising: support frame, support frame as described above include support frame upper layer and support frame lower layer, described Support frame upper layer is equipped at least two solution bottles, and support frame as described above lower layer is equipped at least two dissolutions being used cooperatively with solution bottle Bottle, the water outlet of the solution bottle are connected to the water inlet of the dissolution bottle, and the water outlet of the solution bottle is equipped with flow control Valve;
The dissolution bottle includes autoclave body, and spiral heat conducting pipe is equipped in the autoclave body, is provided with charging at the top of the autoclave body Mouthful, the side of the autoclave body is provided with cold medium pipe, thermal medium pipe, main controller and media outlet pipe, the cold medium pipe and heat The inside of medium tube is provided with solenoid valve and flowmeter, and the bottom of the autoclave body is equipped with discharge port, and the inside of the autoclave body is set It is equipped with stirring rod, the inside of the stirring rod is equipped with temperature sensor;
The cold medium pipe is connected with the import of thermal medium Guan Junyu spiral heat conducting pipe, the outlet of the spiral heat conducting pipe with The connection of media outlet pipe;The flowmeter, temperature sensor are electrically connected with main controller, and the main controller and solenoid valve are electrical Connection, and the main controller is connect with the power supply of outside setting.
Preferably, the top of the autoclave body is equipped with exhaust outlet.
Preferably, the discharge port is equipped with filter device.It can will be in glue by being connected with filter device in discharge port Contaminant filter come out, guarantee the quality of glue.
Preferably, it is described dissolution bottle further include for drive stirring rod rotate No.1 motor and for drive dissolution No. two motors of bottle rotation, the No.1 motor and No. two motors are electrically connected with main controller.
Preferably, the stirring rod and dissolution bottle opposite direction rotation.Opposite direction rotation can eliminate vortex phenomenon, drop simultaneously Low mixing speed reaches and reduces telling on for bubble, ensure that the stirring efficiency of device.
Preferably, the No.1 motor is connected to stirring rod top;It is equipped with below dissolution bottle and connect with No. two motors Rotating platform, dissolution bottle are placed on the rotating platform.
Preferably, the velocity of rotation of the stirring rod is greater than the velocity of rotation of the dissolution bottle.
Compared with the existing technology, the utility model has the following beneficial effects:
Glue production device provided by the utility model is designed by its structure, can effectively reduce occupied area and Convenient glue production, reduces production cost.
The glue dissolves bottle, is provided with temperature sensor, is equipped with circular spiral heat conducting pipe in autoclave body, cooperate it is cold, Thermal medium pipe can need to adjust the intracorporal temperature of kettle at any time according to processing, and be heated evenly material, improve glue Quality is provided with flowmeter, scientific can mix cold and hot medium, to reach the temperature of demand.
Detailed description of the invention
Fig. 1 is that a kind of structure of the process units for the hemostasis-coagulation biological glue that the utility model promotes wound mucosa regeneration is shown It is intended to;
Fig. 2 is a kind of structural schematic diagram of the dissolution bottle of the process units of this practical biological glue;
Fig. 3 is a kind of structural schematic diagram of the stirring structure of the process units of the utility model biological glue;
Wherein, 1, autoclave body;2, spiral heat conducting pipe;3, feed inlet;4, exhaust outlet;5, cold medium pipe;6, thermal medium pipe;7, main Control device;8, media outlet pipe;9, solenoid valve;10, flowmeter;11, discharge port;12, filter device;13, support frame;14, solution Bottle;15, bottle is dissolved;16, flow control valve;21, stirring rod;22, temperature sensor;23, No.1 motor;24, No. two motors; 25, rotating platform.
Specific embodiment
To better illustrate the purpose of this utility model, technical solution and advantage, below in conjunction with specific embodiment to this Utility model is described further.
A kind of embodiment of the process units of the hemostasis-coagulation biological glue described in the utility model for promoting wound mucosa regeneration, The process units of biological glue described in the present embodiment includes:
Support frame 13, support frame 13 include support frame upper layer and support frame lower layer, and it is molten that support frame upper layer is equipped at least two Liquid bottle 14, support frame lower layer are equipped with the dissolution bottle 15 being used cooperatively with solution bottle 14, the water outlet and dissolution bottle 15 of solution bottle 14 Water inlet connection, the water outlet of solution bottle 14 is equipped with flow control valve 16;
Dissolving bottle 15 includes autoclave body 1, is equipped with spiral heat conducting pipe 2 in autoclave body 1, the top of autoclave body 1 is provided with feed inlet 3, kettle The side of body 1 is provided with cold medium pipe 5, thermal medium pipe 6, main controller 7 and media outlet pipe 8, cold medium pipe 5 and thermal medium pipe 6 Inside be provided with solenoid valve 9 and flowmeter 10, the bottom of autoclave body 1 is equipped with discharge port 11, and discharge port 11 is equipped with filter device 12, the top of autoclave body 1 is equipped with exhaust outlet 4, and autoclave body 1 is internally provided with stirring rod 21, and the inside of stirring rod 21 is passed equipped with temperature Sensor 22;
Cold medium pipe 5 and thermal medium pipe 6 are connect with the import of spiral heat conducting pipe 2, the outlet of spiral heat conducting pipe 2 and medium Outlet 8 connects;Flowmeter 10, temperature sensor 22 are electrically connected with main controller 7, and main controller 7 electrically connects with solenoid valve 9 It connects, and main controller 7 is connect with the power supply of outside setting.
Dissolution bottle 15 further include for drive stirring rod 21 rotate No.1 motor 23 and for drive dissolution 15 turns of bottle No. two dynamic motors 24, No.1 motor 23 and No. two motors 24 are electrically connected with main controller 7, and stirring rod 21 and dissolution bottle 15 are anti- Direction rotation, No.1 motor 23 are connected to 21 top of stirring rod;The rotation connecting with No. two motors 24 is equipped with below dissolution bottle 15 Turn platform 25, dissolution bottle 15 is placed on rotating platform 25, and the velocity of rotation of stirring rod 21 is greater than the velocity of rotation of dissolution bottle 15.
Glue production device provided by the utility model uses tier rack type structure, by a variety of different components according to certain suitable Then sequence layering setting utilizes the flowing of gravity control raw material, it is no longer necessary to increase hydraulic pump to carry out power output, both Occupied area, and energy convenient glue production can be effectively reduced, production cost is reduced.For example blood coagulation will can be placed respectively in dissolution bottle Proenzyme and fibrinogen place corresponding reaction solution in solution bottle, due to factor and fibrin respectively Original needs to can use cold and hot medium tube, flowmeter and temperature sensor before reactions to it in subzero 20 DEG C of low-temperature storages Storage temperature is controlled, and when reaction, opens flow control valve, and reaction solution, which enters in dissolution bottle, to be reacted, and when reaction can Further to carry out real-time control to its reaction temperature using cold and hot medium tube, flowmeter and temperature sensor, and discharging It is equipped with filter device at mouthful, glue is filtered removal of impurities.
It dissolves in bottle, is provided with temperature sensor, circular spiral heat conducting pipe is installed in autoclave body, cooperates hot and cold Jie Matter pipe can need to adjust the intracorporal temperature of kettle at any time according to processing, and be heated evenly material, improve the quality of glue, It is provided with flowmeter, scientific can be mixed cold and hot medium, to reach the temperature of demand, by being connected in one end of discharge nozzle There is filter device that can come out the contaminant filter in glue, guarantees the quality of glue.
No.1 motor is for driving stirring rod to rotate, and No. two motors are for driving autoclave body to rotate.By above-mentioned two motor, So that stirring when stirring rod and autoclave body be in motion process, the intracorporal composite glue of kettle can not form vortex, because without Bubble can be generated, and utilizes motor, speed can control, and even mixing speed is very low, and stirring is also very uniform.
Finally, it should be noted that above embodiments are only to illustrate the technical solution of the utility model rather than to this realities With the limitation of novel protected range, although being explained in detail referring to preferred embodiment to the utility model, this field it is common It will be appreciated by the skilled person that can be with the technical solution of the present invention is modified or equivalently replaced, without departing from this reality With the spirit and scope of new technique scheme.

Claims (7)

1. a kind of process units for the hemostasis-coagulation biological glue for promoting wound mucosa regeneration characterized by comprising support frame, Support frame as described above includes support frame upper layer and support frame lower layer, and support frame as described above upper layer is equipped at least two solution bottles, the branch Support lower layer is equipped with the dissolution bottle being used cooperatively with solution bottle, the water inlet company of the water outlet of the solution bottle and the dissolution bottle Logical, the water outlet of the solution bottle is equipped with flow control valve;
The dissolution bottle includes autoclave body, and spiral heat conducting pipe is equipped in the autoclave body, is provided with feed inlet at the top of the autoclave body, institute The side for stating autoclave body is provided with cold medium pipe, thermal medium pipe, main controller and media outlet pipe, the cold medium pipe and thermal medium pipe Inside be provided with solenoid valve and flowmeter, the bottom of the autoclave body is equipped with discharge port, and being internally provided with for the autoclave body is stirred Stick is mixed, the inside of the stirring rod is equipped with temperature sensor;
The cold medium pipe is connected with the import of thermal medium Guan Junyu spiral heat conducting pipe, the outlet of the spiral heat conducting pipe and medium Outlet connection;The flowmeter, temperature sensor are electrically connected with main controller, and the main controller electrically connects with solenoid valve It connects, and the main controller is connect with the power supply of outside setting.
2. promoting the process units of the hemostasis-coagulation biological glue of wound mucosa regeneration as described in claim 1, which is characterized in that The top of the autoclave body is equipped with exhaust outlet.
3. promoting the process units of the hemostasis-coagulation biological glue of wound mucosa regeneration as described in claim 1, which is characterized in that The discharge port is equipped with filter device.
4. promoting the process units of the hemostasis-coagulation biological glue of wound mucosa regeneration as described in claim 1, which is characterized in that The dissolution bottle further includes the No.1 motor for driving stirring rod to rotate and No. two electricity for driving dissolution bottle rotation Machine, the No.1 motor and No. two motors are electrically connected with main controller.
5. promoting the process units of the hemostasis-coagulation biological glue of wound mucosa regeneration as claimed in claim 4, which is characterized in that The stirring rod and dissolution bottle opposite direction rotation.
6. promoting the process units of the hemostasis-coagulation biological glue of wound mucosa regeneration as claimed in claim 4, which is characterized in that The No.1 motor is connected to stirring rod top;It is equipped with the rotating platform connecting with No. two motors below dissolution bottle, dissolves bottle It is placed on the rotating platform.
7. the process units of the hemostasis-coagulation biological glue of the promotion wound mucosa regeneration as described in claim 4,5 or 6, feature It is, the velocity of rotation of the stirring rod is greater than the velocity of rotation of the dissolution bottle.
CN201821326292.8U 2018-08-16 2018-08-16 A kind of process units for the hemostasis-coagulation biological glue promoting wound mucosa regeneration Active CN209020293U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201821326292.8U CN209020293U (en) 2018-08-16 2018-08-16 A kind of process units for the hemostasis-coagulation biological glue promoting wound mucosa regeneration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201821326292.8U CN209020293U (en) 2018-08-16 2018-08-16 A kind of process units for the hemostasis-coagulation biological glue promoting wound mucosa regeneration

Publications (1)

Publication Number Publication Date
CN209020293U true CN209020293U (en) 2019-06-25

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Effective date of registration: 20220112

Address after: 510000 No. 651 Dongfeng East Road, Guangzhou, Guangdong Province

Patentee after: SUN YAT SEN University CANCER CENTER (SUN YAT SEN University AFFILIATED TO CANCER CENTER SUN YAT SEN UNIVERSITY CANCER INSTITUTE)

Address before: Cancer center of Sun Yat sen University, 651 Dongfeng East Road, Guangzhou, Guangdong 510060

Patentee before: Chen Mingyuan