CN209018801U - A kind of new medical Exhaled breath condensate carbon dioxide depassing unit - Google Patents
A kind of new medical Exhaled breath condensate carbon dioxide depassing unit Download PDFInfo
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- CN209018801U CN209018801U CN201821231278.XU CN201821231278U CN209018801U CN 209018801 U CN209018801 U CN 209018801U CN 201821231278 U CN201821231278 U CN 201821231278U CN 209018801 U CN209018801 U CN 209018801U
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- exhaled breath
- gas cylinder
- breath condensate
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- carbon dioxide
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Abstract
The utility model relates to a kind of new medical Exhaled breath condensate carbon dioxide depassing units, by being formed except gas cylinder, rubber hose, right-angled glass pipe, rubber stopper, microcentrifugal tube, gas outlet and iron stand, microcentrifugal tube is placed in except in gas cylinder, rubber stopper closes degasification bottle bottleneck, right-angled glass pipe one end is passed directly into through the pore on rubber stopper except in the microcentrifugal tube in gas cylinder, the other end connects rubber hose, the rubber hose other end is directly connected on the gas outlet of the argon tanks with flowmeter, and apparatus described above can be placed on iron stand and use.Its advantage is shown: (1) sufficiently preventing air contamination, avoid outside air from increasing the exact value of pH value to the influence of Exhaled breath condensate pH result, it is great to the relevant clinical research significance of Exhaled breath condensate pH.(2) structure is simple, stability is good, durability is good, occupies little space, using very convenient.
Description
Technical field
The utility model relates to the field of medical instrument technology, specifically, being a kind of new medical Exhaled breath condensate two
Carbonoxide depassing unit.
Background technique
Airway inflammation plays an important role in the occurrence and development of many respiratory diseases.Antioxygen in Airway surface liquid
A variety of biochemical moleculars such as compound, soluble markers constitute lung tissue and resist inhalable oxide (vanilla in external environment
Smog, ozone, NO), anaphylactogen, microorganism infection barrier, the variation of these molecules can react oxidative damage, inflammation and drug
Pretherapy and post-treatment reaction, therefore can be used for monitoring the variation of pulmonary disease.Exhaled breath condensate
The detection of marker has proved to be assessment and monitors having by force for airway inflammation in (ExhaledBreathCondensate, EBC)
Efficacious prescriptions method is a kind of simple and noninvasive human body lower respiratory tract secretion sampling method.It is sampled with traditional respiratory secretions
Technology (such as sputum induction or bronchoalveolar lavage) is different, collecting condensation be it is very safe, avoid to disease itself into
Journey forms interference, and can carry out repeating detection in a short time, these features collect Exhaled breath condensate to clinic
Doctor is more attractive.Currently, Exhaled breath condensate pH is considered as the biochemistry of the most worthy in Exhaled breath condensate detection
Index confirms endogenous air flue acid by detection Exhaled breath condensate pH in asthma, chronic obstructive pulmonary disease and cystic fibrosis patient
The presence of change.
Commercial means on current market for collecting Exhaled breath condensate have RTubeTM、EcoScreen、
EcoScreenTurbo and TURBO-DECCS etc. is widely used to the relevant clinical research of Exhaled breath condensate.For exhaling
The correlative study of outlet condensate pH can be acidified Exhaled breath condensate due to containing carbon dioxide in expiratory air, cause to be surveyed
Exhaled breath condensate pH value reduces, therefore the related Exhaled breath condensate pH result of study reported on document at present is all removing two
Standardization result after carbonoxide.The process of markization is to be vented 8 minutes with the speed of 350ml/min with argon gas, can achieve and remove
The purpose of carbon dioxide, then obtains accurate and stable Exhaled breath condensate pH value to the greatest extent in Exhaled breath condensate.It has reported at present
Degasification method used in the relevant clinical research led is relatively easy, is that glass pasteur pipet is inserted directly into equipped with expiratory air
In the microcentrifugal tube of the 1.5ml of condensate, glass pipette and flow-controlling meter are separately connected with a tubulature both ends.The party
The main disadvantage of method: sample micro tube is directly contacted with air in degassing procedure, this will be to Exhaled breath condensate pH value
Testing result generates certain influence.
Chinese patent application: CN205569464U discloses a kind of expiratory air condensing collector based on breathing machine ventilation,
Interior trap pipe, outer tube, air inlet pipe, escape pipe, condensate liquid efferent duct including being glass material, interior trap pipe and outer tube are
Test tube shape, interior trap pipe it is opening up, outer tube gap is set in the outside of interior trap pipe, the upper end of outer tube and interior trap pipe
Upper end is linked together and makes to form closed sandwich between outer tube and interior trap pipe, air inlet pipe and an air outlet pipe respectively with housing
Pipe is linked together, and is connected to the inner cavity of air inlet pipe and an air outlet pipe with the sandwich, and condensate liquid efferent duct is set to outer
The downside of casing is simultaneously linked together with outer tube, and the inner cavity of the defeated pipe of condensate liquid is also connected to the sandwich, it is especially suitable not
The patient that can be ventilated automatically.
U.S. Patent application: US20080214947A1 discloses a kind of method and system, can provide every point to subject
Air flue pH changes (or other changing features) during clock EBCpH monitoring, this method and system aid in determining whether disease development
Time course, to achieve the purpose that treat disease.But about a kind of new medical Exhaled breath condensate two of the utility model
Carbonoxide depassing unit yet there are no report.
Utility model content
The purpose of this utility model is in view of the deficiencies of the prior art, to provide a kind of new medical Exhaled breath condensate dioxy
Change carbon depassing unit.
To achieve the above object, the technical scheme adopted by the utility model is that:
A kind of new medical Exhaled breath condensate carbon dioxide depassing unit, including except gas cylinder (1), rubber hose (2), straight
Angle glass tube (3), rubber stopper (4), microcentrifugal tube (5), gas outlet (6), iron stand (7), iron ring (8), bolt (9), it is described
Microcentrifugal tube (5) is placed in except in gas cylinder (1), except gas cylinder (1) is connect with gas outlet (6), rubber stopper (4) closing removes gas cylinder (1)
Bottleneck, right-angled glass pipe (3) one end are passed directly into through the pore on rubber stopper (4) except the microcentrifugal tube (5) in gas cylinder (1)
In, the other end connects rubber hose (2), and rubber hose (2) other end is directly connected to the outlet of the argon tanks with flowmeter
On mouth, iron ring (8), bolt (9) are contained on the iron stand (7), iron ring (8) is fixed on iron stand (7), removes by bolt (9)
Device of air can be placed on iron ring (8) and use.
It is described except gas cylinder (1) is glass except gas cylinder as a preferred embodiment of the utility model, it removes gas cylinder (1)
Overall structure is elongated glass cylinder, except the cross section of gas cylinder (1) is rounded hollow sections, interior diameter 2cm.
As a preferred embodiment of the utility model, the cross-sectional diameter of the rubber hose (2) is greater than right angle
The outer diameter of glass tube (3) is nested in outside right-angled glass pipe (3).
As a preferred embodiment of the utility model, the outer diameter of the right-angled glass pipe (3) is about microcentrifugation
Manage the half of (5) diameter.
As a preferred embodiment of the utility model, there is pore at rubber stopper (4) center, and the pore has
Elasticity can guarantee airtightness after right-angled glass pipe (3) insertion.
As a preferred embodiment of the utility model, the microcentrifugal tube (5) is the microcentrifugation of 1.5ml
Pipe.
As a preferred embodiment of the utility model, the gas outlet (6) is located at the bottom end except gas cylinder (1).
As a preferred embodiment of the utility model, the iron ring (8) has an iron ring.
As a preferred embodiment of the utility model, there are two bolts for the bolt (9).
The utility model advantage is:
1, the straight of condensate liquid sample and outside air is avoided that according to the mating glass depassing unit that microcentrifugal tube designs
Contact, can abundant preventing air contamination, avoid outside air from greatly improving expiratory air to the influence of Exhaled breath condensate pH result
The accuracy of condensate liquid sample pH value testing result is great to the relevant clinical research significance of Exhaled breath condensate pH.
2, rubber material used in device has elasticity big, and larger deformation can be generated under the external force of very little, is removed
Resilient after external force is gone, can be artificial synthesized, cheap advantage is readily available;Except gas cylinder uses glass in device
It is convenient and practical convenient for observation except gas cylinder;Device, which is matched, has iron stand, and iron ring is fixed on iron using iron stand Shi Keyong bolt
It on pallet, places the device on iron ring and uses, convenient for the operation of staff, except the cross section of gas cylinder is cut for circular hollow
Face, interior diameter 2cm enable microcentrifugal tube to be kept upright in except gas cylinder;The outer diameter of right-angled glass tubule is about micro
It is centrifuged the half of pipe diameter, can be convenient in the Exhaled breath condensate in ground insertion tube;Rubber stopper can be closed except gas cylinder
Bottleneck reduces sample and contacts with the direct of outside air;The short end of right-angled glass pipe can closely be connect with rubber hose, really
The patency of outgassing stream is protected;Because the molecular weight of carbon dioxide is greater than argon gas, the gas outlet of the utility model is located at
Bottom end enables the gas outlet at the smooth deaerated bottom of bottle end of the gas of discharge to be discharged;Entire depassing unit can be placed in iron stand
Upper fixation.
3, the utility model structure is simple, stability is good, durability is good, occupies little space, using very convenient.
Detailed description of the invention
Attached drawing 1 is the cross section structure schematic diagram of the medical Exhaled breath condensate carbon dioxide depassing unit of the utility model.
Attached drawing 2 is that the medical Exhaled breath condensate carbon dioxide depassing unit of the utility model is placed on iron stand and uses
Cross section structure schematic diagram.
Specific embodiment
The following further describes the utility model with specific embodiments.It should be understood that these embodiments are merely to illustrate
The utility model rather than limitation the scope of the utility model.In addition, it should also be understood that, having read in the utility model record
After appearance, those skilled in the art can be made various changes or modifications the utility model, and such equivalent forms equally fall within this
Apply for the appended claims limited range.
1. removing 2. rubber hose of gas cylinder, 3. right-angled glass pipe
4. 5. microcentrifugal tube of rubber stopper, 6. gas outlet
7. 8. iron ring of iron stand, 9. bolt
1 new medical Exhaled breath condensate carbon dioxide depassing unit of embodiment
Referring to Figure 1, attached drawing 1 is the cross section structure of the medical Exhaled breath condensate carbon dioxide depassing unit of the utility model
Schematic diagram.A kind of new medical Exhaled breath condensate carbon dioxide depassing unit, including remove gas cylinder 1, rubber hose 2, right angle glass
Glass pipe 3, rubber stopper 4, microcentrifugal tube 5, gas outlet 6, the microcentrifugal tube 5 are placed in except in gas cylinder 1, remove gas cylinder 1 and outlet
Mouth 6 connects, and the closing of rubber stopper 4 removes 1 bottleneck of gas cylinder, and 3 one end of right-angled glass pipe is passed directly into through the pore on rubber stopper 4 except gas cylinder
In microcentrifugal tube 5 in 1, the other end connects rubber hose 2, and 2 other end of rubber hose is directly connected to flowmeter
On the gas outlet of argon tanks.It is described except gas cylinder 1 is glass except gas cylinder as a preferred embodiment of the utility model, it removes
1 overall structure of gas cylinder is elongated glass cylinder, except the cross section of gas cylinder 1 is rounded hollow sections, interior diameter 2cm.As
One preferred embodiment of the utility model, the cross-sectional diameter of the rubber hose 2 are greater than the outer diameter of right-angled glass pipe 3,
It is nested in 3 outside of right-angled glass pipe.As a preferred embodiment of the utility model, the outer diameter of the right-angled glass pipe 3
The about half of 5 diameter of microcentrifugal tube.As a preferred embodiment of the utility model, in the rubber stopper 4
The heart can guarantee airtightness after having pore, the pore that there is elasticity, right-angled glass pipe 3 to be inserted into.One as the utility model
Preferred embodiment, the microcentrifugal tube 5 are the microcentrifugal tubes of 1.5ml.A preferred implementation as the utility model
Scheme, the gas outlet 6 are located at the bottom end except gas cylinder 1.
Referring to figure 2., attached drawing 2 is that the medical Exhaled breath condensate carbon dioxide depassing unit of the utility model is placed in brandreth
The cross section structure schematic diagram used on platform.A kind of new medical Exhaled breath condensate carbon dioxide depassing unit, including remove gas cylinder
1, rubber hose 2, right-angled glass pipe 3, rubber stopper 4, microcentrifugal tube 5, gas outlet 6, iron stand 7, iron ring 8, bolt 9, it is described
Microcentrifugal tube 5 is placed in except in gas cylinder 1, except gas cylinder 1 is connect with gas outlet 6, the closing of rubber stopper 4 removes 1 bottleneck of gas cylinder, right-angled glass
3 one end of pipe is passed directly into through the pore on rubber stopper 4 except in the microcentrifugal tube 5 in gas cylinder 1, the other end connects rubber hose 2,
2 other end of rubber hose is directly connected on the gas outlet of the argon tanks with flowmeter, on the iron stand 7 containing iron ring 8,
Iron ring 8 is fixed on iron stand 7 by bolt 9, bolt 9, and depassing unit can be placed on iron ring 8 and use.As the utility model
A preferred embodiment, it is described except gas cylinder 1 is glass except gas cylinder, except 1 overall structure of gas cylinder is elongated glass cylinder,
Except the cross section of gas cylinder 1 is rounded hollow sections, interior diameter 2cm.It is described as a preferred embodiment of the utility model
The cross-sectional diameter of rubber hose 2 is greater than the outer diameter of right-angled glass pipe 3, is nested in 3 outside of right-angled glass pipe.It is practical new as this
The outer diameter of one preferred embodiment of type, the right-angled glass pipe 3 is about the half of 5 diameter of microcentrifugal tube.As
There is pore at one preferred embodiment of the utility model, 4 center of rubber stopper, and the pore has elasticity, right-angled glass
Pipe 3 can guarantee airtightness after being inserted into.As a preferred embodiment of the utility model, the microcentrifugal tube 5 is 1.5ml
Microcentrifugal tube.As a preferred embodiment of the utility model, the gas outlet 6 is located at the bottom end except gas cylinder 1.Make
For a preferred embodiment of the utility model, the iron ring 8 has an iron ring.One as the utility model is preferred real
Scheme is applied, there are two bolts for the bolt 9.
The application method of the utility model: it in use, the long end of right-angled glass pipe 3 is inserted through the intermediate pore of bottle closure of rubber 4, sets
It sterilizes, dries spare in 75% medical disinfecting alcohol disinfecting disk.The Exhaled breath condensate of about 0.5ml is drawn by liquid-transfering gun
It is placed in microcentrifugal tube 5, wears sterile gloves, specimen tube is placed in except in gas cylinder 1, with the rubber bottle for being plugged right-angled glass pipe 3
4 closing of plug removes 1 bottleneck of gas cylinder, and the end of right-angled glass pipe 3 is led directly in Exhaled breath condensate, and 2 one end of rubber hose is connected argon
Gas tank gas outlet, the other end connect the short end of right-angled glass pipe 3, slowly adjust flowmeter flow to 350ml/min, it is ensured that
Sample is blistered with stable speed, to prevent sample from bubbling over microcentrifugal tube 5, the degasification time about 8 minutes.Degasification is completed
Afterwards, flowmeter is adjusted, flow velocity is gradually decreased, while slowly extracting right-angled glass pipe 3 out microcentrifugal tube 5, to right-angled glass pipe 3
Argon gas tank valve is turned off after being fully drawn out.Then sterile gloves are worn and open rubber stopper 4 rapidly, microcentrifugal tube 5 is taken out and utilizes
PH microelectrode carries out pH value detection.
Condensate liquid sample and outer is avoided that according to the mating glass depassing unit that microcentrifugal tube designs in the utility model
The direct contact of boundary's air, can abundant preventing air contamination, avoid influence of the outside air to Exhaled breath condensate pH result, significantly
The accuracy for improving exhaled breath condensate sample pH value testing result, to the relevant clinical research significance weight of Exhaled breath condensate pH
Greatly.
Rubber material used in device has elasticity big, and larger deformation can be generated under the external force of very little, removes
Resilient after external force, can be artificial synthesized, and cheap advantage is readily available;Except gas cylinder is removed using glass in device
Gas cylinder, it is convenient and practical convenient for observation;Device, which is matched, has iron stand, and iron ring is fixed on brandreth using iron stand Shi Keyong bolt
On platform, places the device on iron ring and use, convenient for the operation of staff, except the cross section of gas cylinder is rounded hollow sections,
Interior diameter 2cm enables microcentrifugal tube to be kept upright in except gas cylinder;The outer diameter of right-angled glass tubule is about microcentrifugation
The half of pipe diameter, it may be convenient in the Exhaled breath condensate in insertion tube;Rubber stopper can be closed except bottle mouth of gas cylinder,
Reduce sample to contact with the direct of outside air;The short end of right-angled glass pipe can closely be connect with rubber hose, it is ensured that
The patency of outgassing stream;Because the molecular weight of carbon dioxide is greater than argon gas, the gas outlet of the utility model is located at bottom end,
The gas outlet at the smooth deaerated bottom of bottle end of the gas of discharge is discharged;Entire depassing unit can be placed on iron stand solid
It is fixed.
The degassing procedure of previous Exhaled breath condensate was relatively easy, and sample is directly and contacting external air, to sample pH
The testing result of value can generate certain influence.The utility model structure is simple, using very convenient, stability is good, durability is good,
It occupies little space, exhaled breath condensate sample is removed gas cylinder bottle sealing by the salt water bottle stopper of rubber, avoids condensate liquid sample and outer
The direct contact of boundary's air greatly improves the accuracy of exhaled breath condensate sample pH value testing result, further promotes disease
The progress of the relevant clinical research of sick Exhaled breath condensate pH value.
The above is only the preferred embodiment of the utility model, it is noted that for the common skill of the art
Art personnel can also make several improvement and supplement without departing from the principle of this utility model, these are improved and supplement
Also it should be regarded as the protection scope of the utility model.
Claims (9)
1. a kind of new medical Exhaled breath condensate carbon dioxide depassing unit, including remove gas cylinder (1), rubber hose (2), right angle
Glass tube (3), rubber stopper (4), microcentrifugal tube (5), gas outlet (6), iron stand (7), iron ring (8), bolt (9), feature
It is, the microcentrifugal tube (5) is placed in except in gas cylinder (1), except gas cylinder (1) is connect with gas outlet (6), rubber stopper (4) is closed
Except gas cylinder (1) bottleneck, right-angled glass pipe (3) one end through the pore on rubber stopper (4) be passed directly into except in gas cylinder (1) it is micro from
In heart pipe (5), the other end connects rubber hose (2), and rubber hose (2) other end is directly connected to the argon tanks with flowmeter
Gas outlet on, iron ring (8), bolt (9) are contained on the iron stand (7), iron ring (8) is fixed on iron stand (7) by bolt (9)
On, depassing unit can be placed on iron ring (8) and use.
2. new medical Exhaled breath condensate carbon dioxide depassing unit according to claim 1, which is characterized in that described
Except gas cylinder (1) is glass except gas cylinder, except gas cylinder (1) overall structure is elongated glass cylinder, except the cross section of gas cylinder (1) is
Rounded hollow sections, interior diameter 2cm.
3. new medical Exhaled breath condensate carbon dioxide depassing unit according to claim 1, which is characterized in that described
The cross-sectional diameter of rubber hose (2) is greater than the outer diameter of right-angled glass pipe (3), is nested in outside right-angled glass pipe (3).
4. new medical Exhaled breath condensate carbon dioxide depassing unit according to claim 1, which is characterized in that described
The outer diameter of right-angled glass pipe (3) is about the half of microcentrifugal tube (5) diameter.
5. new medical Exhaled breath condensate carbon dioxide depassing unit according to claim 1, which is characterized in that described
There is pore at rubber stopper (4) center, and the pore has elasticity, can guarantee airtightness after right-angled glass pipe (3) insertion.
6. new medical Exhaled breath condensate carbon dioxide depassing unit according to claim 1, which is characterized in that described
Microcentrifugal tube (5) is the microcentrifugal tube of 1.5ml.
7. new medical Exhaled breath condensate carbon dioxide depassing unit according to claim 1, which is characterized in that described
Gas outlet (6) is located at the bottom end except gas cylinder (1).
8. new medical Exhaled breath condensate carbon dioxide depassing unit according to claim 1, which is characterized in that described
Iron ring (8) has an iron ring.
9. new medical Exhaled breath condensate carbon dioxide depassing unit according to claim 1, which is characterized in that described
There are two bolts for bolt (9).
Priority Applications (1)
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CN201821231278.XU CN209018801U (en) | 2018-08-01 | 2018-08-01 | A kind of new medical Exhaled breath condensate carbon dioxide depassing unit |
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CN201821231278.XU CN209018801U (en) | 2018-08-01 | 2018-08-01 | A kind of new medical Exhaled breath condensate carbon dioxide depassing unit |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112146956A (en) * | 2020-09-24 | 2020-12-29 | 中国科学院重庆绿色智能技术研究院 | Glass needle tip nanopore filling device based on vacuum method and using method thereof |
-
2018
- 2018-08-01 CN CN201821231278.XU patent/CN209018801U/en active Active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112146956A (en) * | 2020-09-24 | 2020-12-29 | 中国科学院重庆绿色智能技术研究院 | Glass needle tip nanopore filling device based on vacuum method and using method thereof |
CN112146956B (en) * | 2020-09-24 | 2023-06-20 | 中国科学院重庆绿色智能技术研究院 | Glass needle tip nano-hole filling device based on vacuum method and using method thereof |
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