CN208994663U - Biological sample intellectual access mechanism - Google Patents

Abstract

The utility model discloses kind of a biological sample intellectual access mechanisms, including receive transmitting system, movement system and cryogenic storage system；The reception transmitting system can receive cryopreservation tube, and received cryopreservation tube can be transferred at location A；The movement system includes taking tube assembly and transhipment component；It is described to take pipe main component that cryopreservation tube be driven to enter or remove in the operating walk way of low temperature pipe sleeve；The cryogenic storage system is provided with position receiver component, and the position receiver component can position reception storage location of the cryopreservation tube in the cryogenic storage system；The transhipment component can drive the cryopreservation tube at the location A for taking tube assembly to grab or draw to be transported in cryogenic storage system and be stored；Manual intervention is not needed, cryopreservation tube does not need to be exposed in normal temperature environment in the whole process, and operating process does not have an impact cryopreservation tube；Using position receiver component, cryopreservation tube can be stored quickly and accurately, save trouble and labor, also ensure the safety of the environment of biological sample.

Description

Biological sample intellectual access mechanism

Technical field

The utility model relates to biological sample storage apparatus field more particularly to a kind of biological sample intellectual access mechanisms.

Background technique

Profound hypothermia biological sample bank is current field of medicaments and the important infrastructure device of biological field research work, passes through liquid The cryo-conservation of nitrogen can allow the biological tissues such as blood, stem cell and immunocyte stay active for long periods；Depth in the prior art Cryogenic storage system is there are two types of situation: a kind of liquid nitrogen container is stored as hand-operated structures, needs when operator selects cryopreservation tube Cover is opened, the tank body stretched out one's hand into liquid nitrogen container picks out target cryopreservation tube, since storage largely freezes in a liquid nitrogen container The different biological sample of pipe manually tunes while need to consume a longer time, and liquid nitrogen container is opened when manually looking for target Mouth must be sufficiently large, could facilitate and manually take pipe；In this way during finding target, pipe range is frozen by whole in liquid nitrogen container Time is exposed in air themperature, has great harm to biological sample, multi-pass operation even destroys the activity of biological sample；And Manually take pipe operating efficiency low, error rate is high, has biggish security risk to influence the biological sample of storage；

Another profound hypothermia storage system of the prior art, the manipulator of multiple complexity is arranged above liquid nitrogen container, will freeze Pipe is deposited to be transferred in liquid nitrogen container；There are the following problems for this cryogenic storage system:

1. needing first to find suitable storing spot when needing for cryopreservation tube to be stored in liquid nitrogen container or will directly store Disk extracts under normal temperature environment, and cryopreservation tube is stored；While time-consuming and laborious in this way, also to the biological sample product of storage Destruction hidden danger；2. needing for cryopreservation tube to be first exposed in normal temperature environment, it is transferred in liquid nitrogen container by manipulator crawl, is existed in this way Biological sample during unloading in cryopreservation tube will receive influence；3. area occupied is larger, can not due to robot manipulator structure complexity Manipulator is also sealed in a closed environment and is operated simultaneously, even if plus a seal closure it is very huge, it is not easy to operate；4. Multiple manipulator mechanisms are complicated, and the cost is relatively high etc.；

Such as the patent of its Publication No. of patent disclosed in prior art CN107600859A: it needs to biological sample The unit frame hoisting mechanism that cryopreservation tube was stored or first passed through when being extracted setting proposes the sample box for being provided with multiple cryopreservation tubes Be raised to can operating space, then by the first manipulator by sample box be put into inside cryogenic storage tank can operating space, then pass through the Target sample box is transferred in liquid nitrogen container by two manipulators；There is only the above problems for the patented technology of CN107600859A, and And multiple cryopreservation tubes are usually stored by sample box, further by other cryopreservation tubes in sample box in this way in access procedure The influence and destruction of temperature environment are carried out.

Utility model content

The utility model aim is to provide a kind of biological sample intellectual access mechanism, solves existing in the prior art above-mentioned Problem.

The utility model solves technical problem and adopts the following technical scheme that a kind of biological sample intellectual access mechanism, including Receive transmitting system, movement system and cryogenic storage system；The reception transmitting system can receive cryopreservation tube, and can will be received Cryopreservation tube is transferred at location A；The movement system includes taking tube assembly and transhipment component；It is described to take tube assembly including taking pipe master Body part, low temperature pipe sleeve and first are for nitrogen device；The low temperature pipe sleeve includes the operating walk way for holding nitrogen pipe sleeve and inside of perisphere, The appearance nitrogen pipe is set on the operating walk way periphery, and the appearance nitrogen pipe sleeve and the described first connecting for nitrogen mouth for nitrogen device It is logical；It is described to take pipe main component that cryopreservation tube be driven to enter or remove in the operating walk way of low temperature pipe sleeve；The transhipment component can band Cryopreservation tube at the dynamic location A for taking tube assembly to grab or draw is transported in cryogenic storage system；The cryogenic storage system is set It is equipped with position receiver component, and the position receiver component can position reception storage of the cryopreservation tube in the cryogenic storage system Position.

Preferably, the cryogenic storage system further includes liquid nitrogen container and nitrogen cover；The position receiver component includes driving lid Component, sub- cover and sub- lid drive member；Nitrogen cover is provided on the liquid nitrogen container, the drive The lid component can drive the nitrogen tank Cover the progress circumference rotation above liquid nitrogen container；Access path is offered on the nitrogen cover, the sub- cover lid is located at described deposit It takes on channel, the sub- lid drive member carries out driving of uncapping to the sub- cover.

Preferably, the liquid nitrogen container includes tank body and second for nitrogen device, is offered on the tank body into nitrogen hole, described Two being connected to described into nitrogen hole for nitrogen mouth for nitrogen device；Top is provided with tray in the tank body, and the tray can deposit Put multiple cryopreservation tubes；The drive The lid component include drive lid motor and drive lid driving wheel, it is described drive lid motor motor shaft with it is described Drive lid driving wheel coaxial communication；The nitrogen cover upper periphery is peripherally and outwardly extended with the gear teeth, and with the drive lid active gear teeth Wheel engagement connection.

Preferably, the sub- lid drive member includes sub- lid driving motor, sub- lid lifting assembly and sub- lid linking arm；It is described One end of sub- lid linking arm is connect with the sub- cover, and the other end of the sub- lid linking arm and the sub- lid lifting assembly connect It connects, the sub- lid driving motor can drive the sub- lid lifting assembly；It is logical that the sub- lid lifting assembly is provided with guiding Road, under the driving of the sub- lid driving motor, sub- lid lifting assembly can be led described in by sub- lid linking arm band mover cover Elevating movement is carried out to the restriction route in channel.

Preferably, it is described take tube assembly be arranged on the transhipment component, and the transhipment component can drive described in take pipe Component carries out upper and lower, left and right or the position of rotation is mobile.

Preferably, the transhipment component includes transverse movement component, is axially moved component and circumferential movement component；It is described to take Tube assembly is arranged on circumferential movement component, and the circumferential movement component, which can drive, described takes tube assembly to carry out circular-rotation；Institute It states circumferential movement component to be arranged on the axial movement component, the axial movement component can drive the circumferential movement component Carry out the axial movement of vertical direction；The axial movement component is arranged on the transverse movement component, the transverse movement Component can drive axial movement component horizontally to be moved.

Preferably, described to take pipe main component including taking pipe actuator, taking control product and sucker members；The operating walk way The driving channel and lower part for being divided into top take tube passage, and the nitrogen pipe sleeve that holds is set in the periphery for taking tube passage；It is described Take control product be applied in the operating walk way, and it is described take control product can be by the driving for taking pipe actuator in institute Operating walk way is stated to move up and down；Described take offers venting channels in control product, described to take setting above control product There is ventilating joint, the ventilating joint is connected to the upper port of the venting channels；The sucker members and the venting channels Lower port connection；The sucker members can draw cryopreservation tube.

Preferably, the venting channels for taking control product for shaft member, offering up and down in shaft member, shaft member periphery one Side axle is to being provided with rack gear；It is described to take pipe actuator including taking pipe driving motor and taking pipe driving wheel, it is described to take pipe driving motor Motor shaft take pipe driving wheel to connect with described, it is described take pipe driving wheel with it is described take control product peripheral gears engage.

Preferably, the reception transmitting system includes receiving to transfer case, transfer tank and component of uncapping；The reception transfers case On open up and receive door and transfer port, and receptions transfers case and is internally provided with and jack component and received block, and the transfer tank can It being placed on the received block across door is received, the transfer tank on received block can be pushed at transfer port by the jacking component, And it is pushed at location A；The transfer tank includes transfer tank ontology and transfer cover body, and the transfer tank cover cap is closed in transfer On tank ontology；The transfer cover body of transfer tank at the openable location A of component of uncapping.

It preferably, further include control cabinet and seal closure；The reception transmitting system and cryogenic storage system are arranged at In the control cabinet body, the seal closure is sealingly disposed on the control cabinet, and the movement system is arranged described close In sealing cover；Location A receiving port is offered on the control cabinet, the location A receiving port is opposite with the reception transmitting system It answers.

The utility model has the following beneficial effects:

1. position receiver component is arranged in cryogenic storage system, using position receiver component, cryopreservation tube can quickly and accurately into Row storage, save trouble and labor also ensures the safety of the environment of biological sample.

2. cryopreservation tube can directly be received by receiving transmitting system, and can be transported in liquid nitrogen container by movement system, no It requires manual intervention, cryopreservation tube does not need to be exposed in normal temperature environment in the whole process, and operating process does not generate cryopreservation tube It influences；

3. reception transmitting system is provided with, so that the storage of target cryopreservation tube entire liquid nitrogen container in entire access procedure is not It is affected；

4. movement system is arranged, takes tube assembly itself to be provided with first for nitrogen device in the movement system, drawing It is constantly in profound hypothermia environment during target cryopreservation tube；

5. and there is no be arranged multiple complicated machinery hands the case where, it is easy to operate while compact-sized stable so that whole A access procedure efficiency improves, operating time section；

6. seal closure can uniformly be set up to transmitting system, movement system and cryogenic storage system is received, so that entire mechanism It is in closed space and carries out, safety is higher, and stability is strong.

Detailed description of the invention

Fig. 1 is biological sample intellectual access mechanical appearance structural schematic diagram；

Fig. 2 is the in-house reception exploded view of biological sample intellectual access；

Fig. 3 is the biological sample intellectual access structural scheme of mechanism for not showing seal closure；

Fig. 4 is to receive to transfer box structure schematic diagram；

The reception that Fig. 5 is Fig. 4 transfers box structure exploded view；

Fig. 6 is element structure exploded view of uncapping；

Fig. 7 is movement system structural schematic diagram；

Fig. 8 is to take tube assembly structural schematic diagram；

Fig. 9 is the cross section view of Fig. 8；

Figure 10 is transhipment component structure diagram；

Figure 11 is that Figure 10 transports modular construction exploded view；

Figure 12 is movement system and liquid nitrogen container structural schematic diagram；

Figure 13 is liquid nitrogen container schematic diagram of internal structure；

Figure 14 is to drive The lid component structural schematic diagram；

Figure 15 takes tube assembly structural schematic diagram for another performance.

The mark in the figure shows:

100- receives transmitting system；

101-, which is received, transfers case；102- transfer tank；103- uncaps component；104- receives door；105- transfer port；106- jacking Component；107- received block；108- transfer tank ontology；109- transfer cover body；

110- transports cabinet；111- limits output table；112- active reception platform；113- transfers driving assembly；114- output Hole；115- limits delivery outlet；116- guide post；117- support plate；118- maneuvering board；119- receiver hole；120- receiving hole；

1031- extracts disk；1032- driving motor；1033- is oriented to pipe sleeve；1034- lead screw；1035- transition axis；1036- rail Road acts on axis；1037- track groove；1038- guiding axis；

200- movement system；

210- takes tube assembly；2101- takes pipe main component；2102- low temperature pipe sleeve；2103- first is for nitrogen device；2104- holds Nitrogen pipe sleeve；2105- operating walk way；2106- holds nitrogen chamber；2107- takes pipe actuator；2108- takes control product；2109- suction nozzle structure Part；2110- drives channel；2111- takes tube passage；2112- venting channels；2113- ventilating joint；2114- takes pipe driving motor； 2115- takes pipe driving wheel；2116- takes pipe motor support frame；2117- takes shroud；2118- first is for nitrogen supporting table；2119- operation Pipe sleeve；2120- heat-insulating cover；

2130- takes pipe to drive cylinder；2131- takes pipe to drive sliding block；2132- drives support plate；2133- suction pipe part

220- transports component；

2210- transverse movement component；The laterally driven component of 2211-；2212- guide sleeve；2213- sliding panel；2214- guiding Support frame；The first sliding rail of 2215-；2216- guide through hole；The second sliding rail of 2217-；

2220- is axially moved component；The axially driving component of 2221-；2222- is axially moved set；

2230- circumferential movement component；2231- circumferential direction driving assembly；2232- circumferential direction transmission shaft；2233- circumferentially rotates plate；

300- cryogenic storage system；

3001- liquid nitrogen container；3002- nitrogen cover；3003- drives The lid component；The sub- cover of 3004-；The sub- lid drive member of 3005-； The access path 3006-；3007- tank body；3008- second is for nitrogen device；3009- tray；3010- drives lid motor；3011- drives lid Driving wheel；The sub- lid driving motor of 3012-；The sub- lid lifting assembly of 3013-；The sub- lid linking arm of 3014-；3015- guide channel； 3016- position receiver component；

The position 4-A；5- controls cabinet；6- seal closure；The position 7-A receiving port；8- control system.

Specific embodiment

The technical solution of the utility model is further elaborated below with reference to examples and drawings.

Embodiment 1

A kind of biological sample intellectual access mechanism is present embodiments provided, including receives transmitting system 100, movement system 200 and cryogenic storage system 300；The reception transmitting system 100 can receive cryopreservation tube, and can be transferred to received cryopreservation tube At location A 4；The movement system 200 includes taking tube assembly 210 and transhipment component 220；It is described to take tube assembly 210 including taking pipe Main component 2101, low temperature pipe sleeve 2102 and first are for nitrogen device 2103；The low temperature pipe sleeve 2102 includes the appearance nitrogen pipe of perisphere Set 2104 and internal operating walk way 2105, the setting of appearance nitrogen pipe sleeve 2104 are peripheral and described in the operating walk way 2105 Hold nitrogen pipe sleeve 2104 and the described first being connected to for nitrogen mouth for nitrogen device 2103；It is described to take pipe main component 2101 that drive cryopreservation tube Into or remove low temperature pipe sleeve operating walk way 2105 in；The transhipment component 220, which can drive, takes tube assembly 210 to grab or draw Location A at 4 cryopreservation tube be transported in cryogenic storage system 300 and stored.The cryogenic storage system 300 is provided with fixed Position receiving member 3016, and the position receiver component 3016 can position cryopreservation tube connecing in the cryogenic storage system 300 Receive storage location.

It is to move directly to cryopreservation tube in liquid nitrogen container in the prior art, cryopreservation tube also can during shifting this It is exposed in normal temperature environment；After acquiring biological sample, biological sample is placed in cryopreservation tube；In the prior art for cryopreservation tube There are two methods for storage: one is directly cryopreservation tube is stored in the cryogenic storage system of the prior art, the prior art Cryopreservation tube is stored one is the liquid nitrogen container of the manual cryogenic storage system for opening the prior art and is carried out by this cryogenic storage system, Another kind is that manipulator is provided in cryogenic storage system, and manipulator crawl cryopreservation tube is placed into liquid nitrogen container；It is direct in this way The mode that cryopreservation tube is stored, above-mentioned to have illustrated, biological sample long period can be all exposed to room temperature ring by both modes In border, very big security risk is produced to biological sample；The storing mode that another kind is relatively improved be extract biological sample it Afterwards, the holding vessel for having biological sample is stored in transfer tank, cryopreservation tube is transferred to cryogenic storage system using transfer tank In；But be to shift cryopreservation tube using transfer tank for the existing cryogenic storage system of this technology, it is stored by cryopreservation tube When to liquid nitrogen container, it is also desirable to cryopreservation tube is taken out from transfer tank manually, then is put into cryogenic storage system, cryogenic storage system Storing process is as upper two various situations；It is this also to be impacted to the storage condition of biological sample.Either manually will Cryopreservation tube is put into or is put into using manipulator, and cryopreservation tube is not in low temperature environment during this being put into, also can be right Biological sample generates destroying infection in cryopreservation tube；Using position receiver component 3016, cryopreservation tube can be stored quickly and accurately, Save trouble and labor also ensures the safety of the environment of biological sample

The utility model biological sample intellectual access mechanism, is provided with movement system 200, and movement system 200 includes taking pipe Component 210 and transhipment component 220, it is described to take tube assembly 210 including taking pipe main component 2101, low temperature pipe sleeve 2102 and first for nitrogen Device 2103；When carrying out taking pipe to cryopreservation tube, takes pipe main component 2101 first to stretch out operating walk way 2105 and cryopreservation tube is carried out It draws, the cryopreservation tube of absorption is taken pipe main component 2101 to be drawn in operating walk way 2105, because of 2102 perisphere of low temperature pipe sleeve Hold the periphery that operating walk way 2105 is arranged in nitrogen pipe sleeve 2104, and hold nitrogen pipe sleeve 2104 and be connected to first for nitrogen device 2103, That is hold nitrogen pipe sleeve 2104 be provided with hold nitrogen chamber 2106, first for nitrogen device 2103 to hold nitrogen pipe sleeve 2104 appearance nitrogen chamber 2106 For nitrogen, so that entirely holding nitrogen pipe sleeve 2104 is in low temperature state；Also operating walk way 2105 is allowed for be in low temperature environment, Take pipe main component 2101 that cryopreservation tube is drawn in operating walk way 2105 in low temperature environment in this way；Compared with the prior art, originally Utility model is also constantly in cryopreservation tube in low temperature environment during the absorption or crawl to cryopreservation tube, substantially increases life Degree of safety during the storage of object sample.

The utility model further discloses the specific structure for taking pipe main component 2101, described to take the pipe main component 2101 to include It takes pipe actuator 2107, take control product 2108 and sucker members 2109；The driving that the operating walk way 2105 is divided into top is logical Road 2110 and lower part take tube passage 2111, and the nitrogen pipe sleeve 2104 that holds is set in the periphery for taking tube passage 2111；It is described Take control product 2108 be applied in the operating walk way 2105, and it is described take control product 2108 pipe can be taken to drive by described The driving of part 2107 moves up and down in the operating walk way 2105；Described take in control product 2108 offers venting channels 2112, described take is provided with ventilating joint 2113 above control product 2112, the ventilating joint 2113 and the venting channels 2112 upper port connection；The sucker members 2109 are connected to the lower port of the venting channels 2112；The sucker members 2109 can draw cryopreservation tube.

When needing to draw cryopreservation tube, ventilating joint 2113 connects external air compressor and makes sucker members 2109 can draw cryopreservation tube；It is described take pipe actuator 2107 drive it is described take control product 2108 to move downward, until The stretching of sucker members 2109 takes tube passage 2111 to draw cryopreservation tube, and described after absorption to take pipe actuator 2107 to drive described Control product 2108 is taken to move upwards until cryopreservation tube is completely into taking in tube passage 2111；Appearance nitrogen pipe sleeve 2104 is set in described The periphery of tube passage 2111 is taken, first ensure that for nitrogen and take tube passage to appearance nitrogen chamber 2106 always for nitrogen device 2103 2111 in low-temperature condition.

The preferred venting channels for taking control product 2108 for shaft member, offering up and down in shaft member of the present embodiment 2112, shaft member periphery side is axially provided with rack gear；It is described to take pipe actuator 2107 including taking pipe driving motor 2114 and taking pipe Driving wheel 2115, the motor shaft for taking pipe driving motor 2114 take pipe driving wheel 2115 to connect with described, described to take pipe actively Wheel 2115 takes control 2108 peripheral gears of product to engage with described.

Take pipe driving motor 2114 drive it is described take pipe driving wheel 2115 to rotate, take pipe driving wheel 2115 and shaft member periphery Rack gear engagement connection, therefore take pipe driving wheel 2115 that shaft member is driven to be moved upwardly or downwardly；It is offered up and down in shaft member Venting channels 2112, facilitate outside air compressor to act on it；Specifically be provided with take pipe driving motor 2114 take pipe Motor support frame 2116, it is described that pipe driving motor 2114 is taken to be arranged on taking pipe motor support frame 2116, it is described to take control product 2108 take pipe motor support frame 2116 across described, take the motor shaft of pipe driving motor 2114 is outwardly extending to take pipe driving wheel 2115 engage with the gear of 2108 periphery of control product is taken；Shroud is taken taking the upper end of pipe motor support frame 2116 to be provided with 2117, it takes shroud 2117 to be set in the periphery for taking control product 2108, takes shroud 2117 and take inside pipe motor support frame 2116 Form the driving channel 2110；The lower end for taking pipe motor support frame 2116 is fixed with first for nitrogen supporting table 2118, Described first is provided with first for nitrogen device 2103 for 2118 side of nitrogen supporting table；

It is described that control 2108 lower end of product is taken to take 2116 periphery of pipe motor support frame to be arranged with operating tube shield across described 2119, the periphery of the operating tube shield 2119, which is arranged with, holds nitrogen pipe sleeve 2104, the described first wearing for nitrogen pipe for nitrogen device 2103 It crosses and holds the connection of nitrogen pipe sleeve 2104 in the appearance nitrogen chamber 2106 for holding nitrogen pipe sleeve 2104；2104 periphery set of nitrogen pipe sleeve is held in further setting Equipped with heat-insulating cover 2120, the heat-insulating cover 2120 is made of thermal insulation material.

First for 2103 pairs of appearance nitrogen pipe sleeves 2104 of nitrogen device for nitrogen, heat-insulating cover 2120 keeps the temperature it, not by external environment It influences；Control product 2108 is taken to move up and down in operating walk way 2105 and draw cryopreservation tube；This set stable structure, and tie Structure itself occupies little space, and transports convenient for transhipment component to it；After taking tube assembly 210 to draw cryopreservation tube, by transhipment component 220 It is transported in liquid nitrogen container；When transhipment component 220 drives the cryopreservation tube for taking tube assembly 210 to draw to be transported to the suitable position of liquid nitrogen container When setting, take pipe main component 2101 that cryopreservation tube is driven to stretch out operating walk way 2105, sucker members 2109 are decontroled cryopreservation tube and stored.

Certainly here it is also proposed that another kind take tube assembly 210, as shown in figure 15, take tube assembly 210 include take pipe to drive Cylinder 2130 takes pipe driving sliding block 2131, driving support plate 2132 and suction pipe part 2133, and the pipe driving setting of cylinder 2130 is taken to drive It in dynamic support plate 2132, and takes pipe driving cylinder 2130 to taking pipe driving sliding block 2131 to drive upside down, pipe is taken to drive sliding block 2131 other side is fixed with 2133 phase of suction pipe part, and suction pipe part 2133 is with up and down motion；The lower half of suction pipe part 2133 is One for the lower in low temperature environment for nitrogen effect of nitrogen device 2103.

Certainly above two that tube assembly 210 is taken all to draw using absorption mode to cryopreservation tube, it also can be set and grab First-class mode is taken to grab or clamp cryopreservation tube, it is unrestricted here.

In short, to be constantly in crawl or suction process to cryopreservation tube also low for the movement system of the utility model technology In warm environment.

Holding structure in the prior art mentioned above is required to cryopreservation tube exposure at normal temperature, low temperature be allowed to store system System receives storage, there is very big security risk；The biological sample intellectual access mechanism of the utility model is provided with reception and transfers System 100, the reception transmitting system 100 include receiving to transfer case 101, transfer tank 102 and component 103 of uncapping；The reception It transfers to open up on case 101 and receives door 104 and transfer port 105, and the reception transfers case 101 and is internally provided with jacking component 106 With received block 107, the transfer tank 102 may pass through reception door 104 and be placed on the received block 107, the jacking component 106 Transfer tank 102 on received block 107 can be pushed at transfer port 105, and be pushed at location A 4；The transfer tank 102 wraps Transfer tank ontology 108 and transfer cover body 109 are included, the lid of transfer cover body 109 closes on transfer tank ontology 108；It is described to open The transfer cover body 109 of transfer tank 102 at the openable location A 4 of The lid component 103.

The transfer tank 102 that will have cryopreservation tube is directly placed into reception by receiving the reception door 104 of transfer case 101 On seat 107, structure is jacked, 106 are pushed to the transfer tank 102 on received block 107 at location A 4；Using component 103 of uncapping, by A The transfer cover body 109 of transfer tank 102 at position 4 open so that it is convenient to movement system take tube assembly 210 to cryopreservation tube into Row takes pipe.

Specific receive transfers case 101 including transhipment cabinet 110, limit output table 111, active reception platform 112 and transfers Driving assembly 113；The limit output table 111, active reception platform 112 and transfer driving assembly 113 are arranged at the transhipment In cabinet 110；And the reception door 104 being arranged on the transhipment cabinet 110 is hermatic door, and is provided on transhipment cabinet 110 defeated Portal 114；Transfer tank 102 is settable or is placed on the active reception platform 112；In the drive for transferring driving assembly 113 Under dynamic, the active reception platform 112 can drive transfer tank 102 to move to limit 111 direction of output table；The limit output table Limit delivery outlet 115 is offered on 111, and the limit delivery outlet 115 is corresponding with the delivery outlet 114, the two, which is formed, to be turned Send mouth 105；The active reception platform 112 can drive transfer tank 102 successively to wear from the limit delivery outlet 115 and delivery outlet 114 Out；And the active reception platform 112 is moveable to position corresponding with the hermatic door.

Transporting setting in cabinet 110, there are four guide posts 116, and squarely or circular array are arranged；The active reception Platform 112 includes support plate 117 and maneuvering board 118, and the four corners of the support plate 117 are separately fixed at four guide posts On 116, the four corners of the maneuvering board 118 are slidably disposed in respectively in four guide posts 116, and the movement Plate 118 is located at the top of the support plate 117；Receiver hole 119 is offered on the maneuvering board 118, is offered in support plate 117 Receiving hole 120；Transfer tank 102 is put to on receiver hole 119, receiver hole 119 is received and supported to it；In support plate 117 Receiving hole 120 receives the lower half for accommodating transfer tank 102.Transferring driving assembly 113 drives maneuvering board 118 to move upwards, thus Transfer tank 102 on maneuvering board 118 is driven to move upwards, until at least transfer cover body 109 successively from the limit delivery outlet 111 And delivery outlet 114 is pierced by, i.e., at location A 4；It uncaps the transfer cover body 109 of transfer tank 102 at the openable location A 4 of component 103, Facilitate movement system 200 to be transported in liquid nitrogen container the cryopreservation tube absorption in transfer tank 102 to refrigerate.Whole process does not need manually Operation is docked in cryogenic storage system again after will not first taking out cryopreservation tube out of transfer tank 102；Degree of safety mentions significantly It is high.

The biological sample intellectual access mechanism of the utility model further includes control cabinet 5 and seal closure 6；The reception is transferred System 100 and cryogenic storage system 300 are arranged in the control cabinet 5, and the seal closure 6 is sealingly disposed in the control On cabinet 5, and the movement system 200 is arranged in the seal closure 6；Location A receiving port is offered on the control cabinet 5 7, the location A receiving port 7 is corresponding with the reception transmitting system 100.Setting is entire in this way receives transfer tank 102 and centering Turn process that tank is uncapped and whole operation is at middle progress in seal closure 6 and control cabinet 5, securely and reliably.

The present embodiment further discloses a kind of transhipment component 220 of biological sample intellectual access mechanism, described to take tube assembly 210 be arranged on the transhipment component 220, and the transhipment component 220 can drive described in take tube assembly 210 carry out above and below, Left and right or rotation position is mobile.The transhipment component 220 includes transverse movement component 2210, is axially moved 2220 and of component Circumferential movement component 2230；It is described that tube assembly 210 is taken to be arranged on circumferential movement component 2230, the circumferential movement component 2230 Tube assembly 210 is taken to carry out circular-rotation described in can driving；The circumferential movement component 2230 is arranged in the axial movement component On 2220, the axial movement for being axially moved component 2220 and the circumferential movement component 2230 being driven to carry out vertical direction； The axial movement component 2220 is arranged on the transverse movement component 2210, and the transverse movement component 2210 can be with moving axis It is horizontally moved to moving link 2220.

The transverse movement component 2210 includes laterally driven component 2211, guide sleeve 2212, sliding panel 2213 and guiding Support frame 2214；The guide support frame 2214 is fixed bracket, and the left and right sides end of the guide support frame 2214 is respectively provided with There is the first sliding rail 2215, the left and right sides end of the sliding panel 2213 is slidably disposed in first sliding rail On 2215；The middle part of the sliding panel 2213 offers guide through hole 2216, corresponding with the guide through hole 2216 downward Extend and be equipped with guide sleeve 2212, is provided with the second sliding rail 2217 in the guide sleeve 2212；The laterally driven component 2211 are arranged on first sliding rail 2215, and the sliding on guide support frame 2214 to the sliding panel 2213 It is driven；

The axial movement component 2220 includes axially driving component 2221 and axial movement set 2222, the axial movement It covers 2222 peripheries and is provided with slider bar, the axial direction in the case where the slider bar matches effect with second sliding rail 2217 Movement set 2222 can vertical sliding setting in the guide sleeve 2212, axially driving component 2221 setting is led described It is driven on set 2212 and to the sliding for being axially moved set 2222；

The circumferential movement component 2230 includes circumferential driving assembly 2231, circumferential transmission shaft 2232 and circumferentially rotates plate 2233, in axial movement set 2222, the circumferential direction driving assembly 2221 can be driven for circumferential direction transmission shaft 2232 setting The circumferential direction transmission shaft 2232 is rotated, the lower end of the circumferential direction transmission shaft 2232 extend axials movement set 2222 and Described one end for circumferentially rotating plate 2233 is vertically fixedly connected；The other end for circumferentially rotating plate 2233 is provided with to be taken with described Tube assembly 210.

Tube assembly 210 is taken to be arranged on the circumferential movement component 2230, the circumferential movement component 2230 is arranged in institute It states and is axially moved on component 2220, the axial movement component 2220 is arranged on the transverse movement component 2210；It needs pair When the cryopreservation tube for having biological sample extracts, in the horizontal direction, laterally driven component 2211 drives sliding panel 2213 to exist Transverse shifting is carried out on guide support frame 2214, so that tube assembly 210 be taken to carry out transverse shifting；In the vertical direction, axial to drive Dynamic component drives to be axially moved to cover and move up and down, and takes tube assembly to move up and down to drive；Circumferential driving assembly 2230 can drive circumferential transmission shaft 2232 to rotate, and circumferentially rotate plate 2233 centered on circumferential 2232 lower end of transmission shaft to drive Point is rotated, and takes tube assembly 210 to rotate to drive；Tube assembly 210 is taken to can relate in this way, substantially increasing Range, improve the operability of extraction；Structure is relatively easy, easy to operate.Meanwhile being axially moved the axial direction of component 2220 Movement set 2222 is the circumferential movement component 2230 in the guide sleeve 2212 being arranged on the transverse movement component 2210 Circumferential transmission shaft 2232 be arranged in it is described axial movement component 2220 on axials movement set 2222 in so that laterally transport Occupied space that is dynamic and being axially moved is substantially reduced, while circumferential movement component 2230 is arranged, the week of circumferential movement component 2230 It is being axially moved in set 2222 to the setting of transmission shaft 2232, so that being axially moved setting for component 2220 and circumferential movement component 2230 It sets nested against one another, greatly reduces the occupancy in space, and stable structure, easy to operate, mechanism advantage of lower cost itself.

The further component 103 of uncapping for receiving transmitting system 100 includes extracting disk 1031, driving motor 1032, guiding Pipe sleeve 1033, lead screw 1034, transition axis 1035 and rail effect axis 1036；The driving motor 1032 is to the lead screw 1034 One end is driven, and the other end of the lead screw 1034 is mutually fixed with described 1035 one end of transition axis, the transition axis 1035 The other end is fixedly connected with described 1036 one end of rail effect axis, the other end and extraction disk 1031 of the rail effect axis 1036 It is connected；The guiding pipe sleeve 1033 is located at the rail effect axis 1036 and 1035 lower end of transition axis periphery, and is oriented to pipe sleeve The Z-shaped or N shape track groove 1037 opened up on 1033；Extending radially outwardly on the rail effect axis 1036 has guiding axis 1038, One end of the guiding axis 1038 is fallen into described Z-shaped or N shape track groove 1037.It extracts 1031 lower end surface of disk and is provided with electromagnetism Iron.

When transfer tank 102 is pushed at location A 4 by above-mentioned reception transmitting system 100, extracts disk 1031 and utilize electromagnetism Iron draws the transfer cover body 109 of transfer tank 102, and rotary motion is become linear axis by lead screw 1034 by driving motor 1032 To movement, by the connection of transition axis 1035, the guiding axis 1038 of rail effect axis 1036 is guided in the limit of track groove 1037 Under do curve lifting movement so that extract disk 1031 draw transfer cover body 109 open and leave the upper of transfer tank ontology 108 Side, the convenient cryopreservation tube in transfer tank 102 are drawn.

This set changes the structure of complicated machinery hand in the prior art, facilitates sealing simultaneously, easy to operate.

The utility model further discloses cryogenic storage system 300, and the cryogenic storage system 300 further includes liquid nitrogen container 3001 and nitrogen cover 3002, the position receiver component 3016 includes driving The lid component 3003, sub- cover 3004 and son lid driving structure Part 3005；Nitrogen cover 3002 is provided on the liquid nitrogen container 3001, the drive The lid component 3003 can drive the nitrogen cover 3002 Circumference rotation is carried out above liquid nitrogen container 3001；Access path 3006, the sub- cover are offered on the nitrogen cover 3002 3004 lids are located on the access path 3006, and the sub- lid drive member 3005 carries out drive of uncapping to the sub- cover 3004 It is dynamic.

The liquid nitrogen container 3001 includes tank body 3007 and second for nitrogen device 3008, is offered on the tank body 3007 into nitrogen Hole, the described second being connected to described into nitrogen hole for nitrogen mouth for nitrogen device 3008；Top is provided with storage in the tank body 3007 Disk 3009, the tray 3099 can store multiple cryopreservation tubes；The drive The lid component 3003 includes driving lid motor 3010 and driving to cover Driving wheel 3011, the motor shaft for driving lid motor 3010 and 3011 coaxial communication of drive lid driving wheel；The nitrogen cover 3002 upper peripheries are peripherally and outwardly extended with the gear teeth, and engage connection with 3011 gear of drive lid driving wheel.

The sub- lid drive member 3005 includes sub- lid driving motor 3012, sub- lid lifting assembly 3013 and sub- lid linking arm 3014；One end of the sub- lid linking arm 3014 is connect with the sub- cover 3004, the other end of the sub- lid linking arm 3014 It is connect with the sub- lid lifting assembly 3013, the sub- lid driving motor 3012 can drive the sub- lid lifting assembly 3013 It is dynamic；The sub- lid lifting assembly 3013 is provided with guide channel 3015, under the driving of the sub- lid driving motor 3012, sub- lid Lifting assembly 3013 can by sub- lid linking arm 3014 with mover cover 3004 along the guide channel 3015 restriction route into Row elevating movement.

There is cryopreservation tube transfer tank 102 in the reception of above-mentioned reception transmitting system 100, and transfer tank 102 is transferred to location A At 4, the transfer cover body 109 of transfer tank 102 is opened using component 103 of uncapping, movement system 200 is drawn in transfer tank 102 Cryopreservation tube；Sub- lid driving motor 3012 drives sub- lid lifting assembly 3013 to be ascending motion, therefore sub- Gai Lian in the axial direction simultaneously It connects arm 3014 to rise with mover cover 3004, so that sub- cover 3004 is opened from access path 3006；Sub- lid lifting group Guide channel 3015 is provided on part 3013, sub- lid lifting assembly 3013 can be by sub- lid linking arm 3014 with mover cover 3004 Restriction route along the guide channel 3015 carries out elevating movement.Therefore sub- cover 3004 can be brought away from access path 3006 Side, the cryopreservation tube for facilitating movement system 200 to draw enter liquid nitrogen container 3001 by access path 3006.

Tray 3009 is provided in the tank body of liquid nitrogen container 3001, if at this time access path 3006 for tray 3009 Position be not suitable for storing, using The lid component 3003 is driven, the drive The lid component 3003 can drive the nitrogen cover 3002 in liquid Circumference rotation is carried out above nitrogen tank 3001, so that nitrogen cover 3002 rotates, it is known that the corresponding tray 3009 in access path 3006 Position be suitable target position；It drives the driving of lid motor 3010 and drives the rotation of lid driving wheel 3011, drive lid driving wheel 3011 and nitrogen The gear teeth meshing that 3002 upper periphery of cover peripherally and outwardly extends, therefore nitrogen cover 3002 rotates, until access path 3006 Set suitable position.

Above-mentioned setting changes the status for needing entirely to open liquid nitrogen container storage cryopreservation tube in the prior art；But it sets It has set and has opened up the lesser access path 3006 of opening on nitrogen cover 3002, the sub- lid of cover 3004 is set on access path 3006 and is set. Positioning device can be set in tray 3009, directly go to the target position of tray 3009 at access path 3006； Access path 3006 may be configured as kidney slot etc., unrestricted here；Memory channel 3006 forms storage positioning, not only effectively Shortening storage time, be not exposed to original cryopreservation tube in liquid nitrogen container 3001 in normal temperature environment, also simultaneously to the jelly of access One positioning function of pipe is deposited, is more convenient for storing, it is convenient, the time is saved, safety is improved.

The utility model biological sample intellectual access mechanism is provided with control system 8, and the control system 8 is respectively to reception Transmitting system 100, movement system 200 and cryogenic storage system 300 are controlled.Entire biological sample intellectual access mechanism structure It is compact, it is thus relatively uncomplicated, the safety of biological sample is greatly improved.

The sequencing of above embodiments is not only for ease of description, represent the advantages or disadvantages of the embodiments.

Finally, it should be noted that above embodiments are only to illustrate the technical solution of the utility model, rather than its limitations； Although the utility model is described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: It is still possible to modify the technical solutions described in the foregoing embodiments, or part of technical characteristic is carried out etc. With replacement；And these are modified or replaceed, various embodiments of the utility model technology that it does not separate the essence of the corresponding technical solution The spirit and scope of scheme.

Claims (10)

1. a kind of biological sample intellectual access mechanism, which is characterized in that including receiving transmitting system, movement system and low temperature storage System；

The reception transmitting system can receive cryopreservation tube, and received cryopreservation tube can be transferred at location A；

The movement system includes taking tube assembly and transhipment component；

It is described to take tube assembly including taking pipe main component, low temperature pipe sleeve and first for nitrogen device；

The low temperature pipe sleeve includes the operating walk way for holding nitrogen pipe sleeve and inside of perisphere, and the appearance nitrogen pipe is set on the behaviour Make channels peripheral, and the appearance nitrogen pipe sleeve and the described first being connected to for nitrogen mouth for nitrogen device；

It is described to take pipe main component that cryopreservation tube be driven to enter or remove in the operating walk way of low temperature pipe sleeve；

The transhipment component can drive the cryopreservation tube at the location A for taking tube assembly to grab or draw to be transported to cryogenic storage system It is interior；

The cryogenic storage system is provided with position receiver component, and the position receiver component can position cryopreservation tube described low Reception storage location in gentle storage system.

2. biological sample intellectual access according to claim 1 mechanism, which is characterized in that the cryogenic storage system is also wrapped Include liquid nitrogen container and nitrogen cover；

The position receiver component includes driving The lid component, sub- cover and sub- lid drive member；

Nitrogen cover is provided on the liquid nitrogen container, the drive The lid component can drive the nitrogen cover to carry out circumference above liquid nitrogen container Rotation；Access path is offered on the nitrogen cover, the sub- cover lid is located on the access path, and the sub- lid drives structure Part carries out driving of uncapping to the sub- cover.

3. biological sample intellectual access according to claim 2 mechanism, which is characterized in that the liquid nitrogen container include tank body and Second for nitrogen device, offers on the tank body into nitrogen hole, the described second being connected to described into nitrogen hole for nitrogen mouth for nitrogen device；

Top is provided with tray in the tank body, and the tray can store multiple cryopreservation tubes；

The drive The lid component includes driving lid motor and drive lid driving wheel, the motor shaft and the drive lid driving wheel for driving lid motor Coaxial communication；

The nitrogen cover upper periphery is peripherally and outwardly extended with the gear teeth, and engages connection with the drive lid sprocket gear.

4. biological sample intellectual access according to claim 3 mechanism, which is characterized in that the sub- lid drive member includes Sub- lid driving motor, sub- lid lifting assembly and sub- lid linking arm；One end of the sub- lid linking arm is connect with the sub- cover, institute The other end for stating sub- lid linking arm is connect with the sub- lid lifting assembly, and the sub- lid driving motor can be to the sub- lid lifting group Part is driven；

The sub- lid lifting assembly is provided with guide channel, and under the driving of the sub- lid driving motor, sub- lid lifting assembly can Restriction route by sub- lid linking arm with mover cover along the guide channel carries out elevating movement.

5. biological sample intellectual access according to claim 1 mechanism, which is characterized in that described that tube assembly is taken to be arranged in institute It states on transhipment component, and the transhipment component can drive the position movement for taking tube assembly to carry out upper and lower, left and right or rotation.

6. biological sample intellectual access according to claim 5 mechanism, which is characterized in that the transhipment component includes laterally Moving link is axially moved component and circumferential movement component；

Described that tube assembly is taken to be arranged on circumferential movement component, the circumferential movement component, which can drive, described takes tube assembly to be justified Week rotation；The circumferential movement component is arranged on the axial movement component, and the axial movement component can drive the week The axial movement of vertical direction is carried out to moving link；The axial movement component is arranged on the transverse movement component, institute Stating transverse movement component can drive axial movement component horizontally to be moved.

7. biological sample intellectual access according to claim 1 mechanism, which is characterized in that described to take pipe main component including taking Pipe actuator takes control product and sucker members；

The operating walk way is divided into the driving channel on top and lower part takes tube passage, and the appearance nitrogen pipe sleeve, which is set in, described takes pipe The periphery in channel；It is described take control product be applied in the operating walk way, and it is described take control product can take pipe by described The driving of actuator moves up and down in the operating walk way；

Described take offers venting channels in control product, described take is provided with ventilating joint, the ventilation above control product Connector is connected to the upper port of the venting channels；The sucker members are connected to the lower port of the venting channels；

The sucker members can draw cryopreservation tube.

8. biological sample intellectual access according to claim 7 mechanism, which is characterized in that described to take control product for axis Part offers venting channels up and down in shaft member, and shaft member periphery side is axially provided with rack gear；

It is described that take pipe actuator include taking pipe driving motor and taking pipe driving wheel, the motor shaft for taking pipe driving motor with it is described Pipe driving wheel is taken to connect, it is described that pipe driving wheel is taken to take control product peripheral gears to engage with described.

9. biological sample intellectual access according to claim 1 mechanism, which is characterized in that the reception transmitting system includes It receives and transfers case, transfer tank and component of uncapping；

The reception, which transfers to open up on case, receives door and transfer port, and the reception transfers case and is internally provided with jacking component and connects Seat is received, the transfer tank may pass through reception door and be placed on the received block, and the jacking component can be by the transfer on received block Tank is pushed at transfer port, and is pushed at location A；

The transfer tank includes transfer tank ontology and transfer cover body, and the transfer tank cover cap closes on transfer tank ontology；

The transfer cover body of transfer tank at the openable location A of component of uncapping.

10. biological sample intellectual access according to claim 1 mechanism, which is characterized in that further include control cabinet and close Sealing cover；

The reception transmitting system and cryogenic storage system are arranged in the control cabinet body, and the seal closure is sealingly disposed in On the control cabinet, and the movement system is arranged in the seal closure；

Location A receiving port is offered on the control cabinet, the location A receiving port is corresponding with the reception transmitting system.