CN208973791U - Can automatic-sealed sampling capsule endoscope - Google Patents

Can automatic-sealed sampling capsule endoscope Download PDF

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Publication number
CN208973791U
CN208973791U CN201820928116.5U CN201820928116U CN208973791U CN 208973791 U CN208973791 U CN 208973791U CN 201820928116 U CN201820928116 U CN 201820928116U CN 208973791 U CN208973791 U CN 208973791U
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China
Prior art keywords
capsule
needle tubing
conduit
heating
sealing
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Withdrawn - After Issue
Application number
CN201820928116.5U
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Chinese (zh)
Inventor
包宇晖
杨戴天杙
明繁华
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Anhan Science And Technology (wuhan) Co Ltd
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Anhan Science And Technology (wuhan) Co Ltd
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Priority to CN201820928116.5U priority Critical patent/CN208973791U/en
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Abstract

The utility model relates to it is a kind of can automatic-sealed sampling capsule endoscope, it includes capsule housing, sealing-plug, needle tubing, partition heater, heat ring, spring, heat fusible conduit, capsule controller, capsule sensor, capsule support plate and needle tubing mounting bracket, capsule housing includes control panel chamber, acquisition device chamber and sealing sampling cavity, it is separated between control panel chamber and acquisition device chamber by capsule support plate, it is separated between acquisition device chamber and sealing sampling cavity by sealing-plug, capsule housing is equipped with thieff hatch, capsule support plate is equipped with the conduit being connected to thieff hatch, capsule controller and the setting of capsule sensor are intracavitary in control panel, partition heater is fixed on acquisition device cavity wall.The utility model can complete the alimentary canal liquid sample of active, while after sampling, sample is effectively isolated out in sampling pool, avoid leaking and pollute.

Description

Can automatic-sealed sampling capsule endoscope
Technical field
The utility model relates to capsule endoscope technical fields, and in particular to one kind can peep in the sampling capsule of automatic-sealed Mirror.
Background technique
The utility model proposes before, document Gu and Gu, 1996 (" Ingestibel Gastrointestinal Sampling Devices:State-of-the-Art and Future Directions "), it is sealed using some special materials The firmly vacuum tube chamber in capsule, in specific alimentary canal liquid, these plugs degradation, so that external substance is sucked lumen.It should Degradation material is utilized as triggering in the design of document, and the shortcomings that this design form is: the first, triggering sampling opportunity can Control property is poor;The second, sampled targets are limited by degradation material property, need to understand in advance the property of target liq, and selection is suitable Degradation material;Third, thieff hatch cannot be sealed up again after opening, and sample is easy leakage or contaminated.
Summary of the invention
The purpose of this utility model is to provide it is a kind of can automatic-sealed sampling capsule endoscope, the capsule endoscope energy The alimentary canal liquid sample for completing active, while after sampling, sample is effectively isolated out in sampling pool, avoid leakage and Pollution.
To achieve the above object, designed by the utility model can automatic-sealed sampling capsule endoscope, feature exists In: it includes capsule housing, sealing-plug, needle tubing, partition heater, heating ring, spring, heating fusible conduit, capsule control Device, capsule sensor, capsule support plate and needle tubing mounting bracket, wherein capsule housing includes control panel chamber, acquisition device chamber With sealing sampling cavity, control panel chamber separated with acquisition device chamber by capsule support plate, acquisition device chamber with seal sampling cavity by Sealing-plug separates, and capsule housing side wall is equipped with thieff hatch, and it is intracavitary that capsule controller and capsule sensor are located at control panel, partition Heater is fixed on acquisition device cavity wall, and both ends of the spring is separately fixed on partition heater and needle tubing mounting bracket, needle tubing Pipe shaft be fixed in the through-hole of needle tubing mounting bracket, needle tubing syringe needle be inserted into sealing-plug, capsule support plate be equipped with abutment sleeve, The middle through-hole of partition heater is fixedly connected with abutment sleeve outer ring, and abutment sleeve inner ring installation heating ring is heated and set in ring Heating fusible conduit is set, the connector of needle tubing is located in heating fusible conduit, and can be under the drive of needle tubing mounting bracket It is translated in heating fusible conduit, the connector of needle tubing is connected to by heating fusible conduit with thieff hatch, needle tubing installation branch The bottom end of frame is fixedly connected by fusible material fixedly connected part with partition heater, and control panel chamber side wall is additionally provided with and samples The sensor detection window that hole is arranged side by side, capsule sensor senses head are sealingly mounted in sensor detection window;
The signal input part of the signal output end connection capsule controller of capsule sensor, two temperature controls of capsule controller Signal output end is separately connected the thermal control signals input terminal of heating ring and partition heater.
The utility model has the beneficial effects that:
1. the utility model uses vacuum tank as sampling pool, with the other component relative separations of capsule.Sampling pool is complete Property is good, is easily assembled, processes, sterilizes, seals.After sampling, sample is easy storage, transport and sampling;
2, the utility model is sampled using microsyringe structure, and small, easy holding sampling pool is destroyed to sampling pool Leakproofness and integrality;
3, the utility model uses low melting material as a part of liquid communication conduit, by heating molten material, Occluding catheter completes sampling pool closing, avoids sample leakage and is contaminated;
4, the sampling pool closure designs structure of the molten resistive of conduit is simple in the utility model, accounts for small in size;
5, in the utility model capsule controller control partition heater heating, the fusible material fixedly connected part every Board heating apparatus temperature fuses after increasing, and spring elongation makes the syringe needle of needle tubing pierce through sealing-plug, realizes endoscope sampling, entire mistake Journey is safe and reliable.
6, sensor detection window with thief hatch is located at the ipsilateral of capsule in the utility model;Be conducive to believe using sensor Breath carries out lesion detection, assist sample comprehensive analysis (according to sensor information, such as image, it is possible to find such as bleeding in alimentary canal, A variety of lesions such as ulcer, polyp can provide reference information for sample analysis);It is accurately fixed to be conducive to carry out using sensor information Position (such as image can get accurate alimentary canal location information);Be conducive to carry out the judgement of air-liquid environment using sensor information (capsule system is mainly used for liquid sample in the digestive tract, if thief hatch is not in liquid environment, can when sampling starting It can lead to fluid sample undersampling, lead to this sampling failure, by sensor information, such as image, can determine whether that thief hatch is No submergence in a liquid, such as captures bubble, suspended matter, liquid-gas interface.After judging thief hatch submergence in a liquid, just meeting Or suggest starting sampling, to improve the success rate of sampling);Be conducive to (work as biography using sensor information exclusion residue blocking interference Sensor information, such as image, when a large amount of swill of middle discovery, will not or it is not recommended that starting sampling, avoids residue blocking sampling Mouthful);Be conducive to reduce capsule using sensor information and be detained risk and (for active sampling capsule, can be produced in thief hatch when sampling Low pressure is given birth to, liquid is inhaled into sampling pool in alimentary canal.If thief hatch touch mucous membrane in alimentary canal, it may cause capsule and be adsorbed on It on mucous membrane, is no longer excreted with gastrointestinal motility, causes to be detained.When by sensor information, such as image judges that capsule passes through When crossing narrow zone or being close to mucous membrane, sampling will not be opened, the risk of delay is reduced).
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model;
Fig. 2 is structural schematic diagram when the utility model starts sampling;
Fig. 3 is structural schematic diagram when rear enclosed sampling pool is completed in the utility model sampling;
Fig. 4 is the utility model electric control part functional block diagram.
Wherein, 101-capsule housings, 102-sealing sampling cavities, 103-sealing-plugs, 104-needle tubings, 105-needle tubings peace Fill bracket, 106-fusible material fixedly connected parts, 107-partition heaters, 108-rubber sleeves, 109-heating rings, 110- Spring, 111-thieff hatch, 112-heating fusible conduits, 113-conduits, 114-capsule controllers, 115-capsules sensing Device, 116-acquisition device chambers, 117-capsule support plates, 118-control panel chambers, 119-abutment sleeves, 120-middle parts are logical Hole, 121-raised protective layers, 122-sensor detection windows, liquid in 201-alimentary canals.
Specific embodiment
Below in conjunction with the drawings and specific embodiments, the utility model is described in further detail:
It is a kind of can automatic-sealed sampling capsule endoscope, as shown in figures 1-4, it includes capsule housing 101, sealing-plug 103 (rubber materials), needle tubing 104, partition heater 107, heating ring 109, spring 110, heating fusible conduit 112, capsule Controller 114, capsule sensor 115, capsule support plate 117 and needle tubing mounting bracket 105, wherein capsule housing 101 includes electricity Equipment cavity 118, acquisition device chamber 116 and sealing sampling cavity 102 are controlled, by glue between control panel chamber 118 and acquisition device chamber 116 Capsule support plate 117 separates (capsule support plate 117 is fixedly connected with the inner wall of capsule housing 101), acquisition device chamber 116 and sealing It is separated between sampling cavity 102 by sealing-plug 103,101 side wall of capsule housing is equipped with thieff hatch 111, and capsule support plate 117 is equipped with The conduit 113 being connected to thieff hatch 111, the capsule controller 114 and capsule sensor 115 are arranged in control panel chamber 118 Interior, partition heater 107 is fixed on 116 inner wall of acquisition device chamber, and 110 one end of spring is fixedly connected with partition heater 107, bullet 110 other end of spring is fixedly connected with needle tubing mounting bracket 105, and the center that the pipe shaft of needle tubing 104 is fixed on needle tubing mounting bracket 105 is logical The syringe needle of Kong Zhong, needle tubing 104 are inserted into sealing-plug 103, and capsule support plate 117 is equipped with abutment sleeve 119, partition heater 107 middle through-hole 120 is fixedly connected with the outer ring of abutment sleeve 119, and the inner ring installation heating ring 109 of abutment sleeve 119 adds Setting heating fusible conduit 112 in hot ring 109, the connector of needle tubing 104 are located in heating fusible conduit 112, and can be It is translated in heating fusible conduit 112 under the drive of needle tubing mounting bracket 105, the connector of needle tubing 104 is fusible by heating Disconnected conduit 112 is connected to conduit 113, and the bottom end of needle tubing mounting bracket 105 is added by fusible material fixedly connected part 106 with partition Hot device 107 is fixedly connected, and 118 side wall of control panel chamber is additionally provided with the sensor detection window being arranged side by side with thieff hatch 111 122,115 sensing head of capsule sensor is sealingly mounted in sensor detection window 122, and the top of mounting bracket 105 is towards close Blocking 103, under original state, spring 110 is in compressive state, be limited in needle tubing mounting bracket 105 and partition heater 107 it Between.
The signal input part of the signal output end connection capsule controller 114 of capsule sensor 115, capsule controller 114 Two temperature signal output ends be separately connected heating ring 109 and partition heater 107 thermal control signals input terminal.It is described Capsule sensor 115 is used to obtain the environmental information around thieff hatch 111, and capsule controller 114 is used for the sampling according to acquisition Environmental information around hole 111 is accurately positioned thieff hatch 111, and judges the air-liquid environment in 111 region of thieff hatch, glue Capsule sensor 115 is imaging sensor, pH sensor, pressure sensor, temperature sensor or their combination.Capsule control It is also integrated with wireless communication module in device 114, which receives control and refer to for carrying out wireless communication with external experts system It enables, feeds back testing result.
Preferably, the inner ring of the heating ring 109 also covers rubber sleeve 108, and the connection muzzle of needle tubing 104 is in rubber sleeve 108 inner ring, the heating fusible conduit 112 is between rubber sleeve 108 and capsule support plate 117.Rubber sleeve 108 can be protected Rubber sleeve 108 is demonstrate,proved by stable position.Needle tubing 104 can be under the drive of needle tubing mounting bracket 105 in the plug pipe axis of rubber sleeve 108 To movement, the connector of the needle tubing 104 is connected to by the plug pipe of rubber stopper 108 with heating fusible conduit 112, is heated fusible Disconnected conduit 112, plug pipe and needle tubing 104 are coaxially connected.
Preferably, the sealing-plug 103 is equipped with opposite with the syringe needle of needle tubing 104 towards the side of sealing sampling cavity 102 Raised protective layer 121.Raised protective layer 121 can guarantee that sealing-plug 104 will not be punctured under original state.It is led in needle tubing 104 Logical needle tubing, when original state, are inserted in sealing-plug 104, so that needle slope is all wrapped in sealing-plug 104, can play close Envelope effect: when not sampling, outside liquid will not be entered in capsule.
Preferably, the fusing-off temperature of the fusible material fixedly connected part 106 is 45~50 DEG C.The heating fusible is led The conduit fusing seal temperature of pipe 112 is 60~90 DEG C, and the temperature is relatively high, but heats the setting of fusible conduit 112 and exist In the middle part of capsule stimulation will not be generated to human body.
Preferably, the fusible material fixedly connected part 106 fuses after the raising of 107 temperature of partition heater, spring 110 Elongation drives needle tubing mounting bracket 105 to translate to 103 direction of sealing-plug, and the syringe needle of needle tubing 104 is made to pierce through sealing-plug 103, thus It is connected to thieff hatch 111, conduit 113, heating fusible conduit 112, needle tubing 104 with sealing sampling cavity 102.
Preferably, the heating fusible conduit 112 fuses after the raising of 107 temperature of partition heater, heats fusible Conduit 112 is closed, and is closed between needle tubing 104 and conduit 113.
Preferably, the fusible material fixedly connected part 106 is nylon yarn, hot melt adhesive or melting range at 45~50 DEG C Low-melting alloy (low-melting alloy is usually made of the low-melting-point metals element such as Bi, Sn, Pb, In), it is special according to different materials Property, needle tubing mounting bracket 105 can be by 106 system of fusible material fixedly connected part, viscous glutinous or be stuck on partition heater 107.
Preferably, the material of the heating fusible conduit 112 is ethylene-vinyl acetate copolymer (EVA) or POE plastics Or solid paraffin.Fusible conduit 112 is heated when installation with stress centainly radially inward.Make when fusing in this way The side wall for heating fusible conduit 112 is easier inwardly flowing, is closed heating fusible conduit 112.
Preferably, the thieff hatch 111 has multiple, and multiple thieff hatch 111 are evenly arranged on the side wall of capsule housing 101.Fig. 1 Two thieff hatch 111 are illustrated in~3, conduit 113 presents T-shaped with needle tubing 104.The quantity of actually thieff hatch 111 is unlimited It can be other numbers in 2.Side sampling in the design is easier to realize more sampling mouth structures, is suitble in such as small intestine etc. The liquid of narrow zone absorption mucomembranous surface.
In the utility model, the overall length of capsule housing 101 is not more than 32mm, and diameter is not more than 12mm.Seal sampling cavity 102 Volume range with sampling pool 402 is in 0.4mL~0.7mL, and the volume for sealing sampling cavity 102 is preferably 0.4mL~0.7mL, very Reciprocal of duty cycle range is -90kPa~-80kPa, guarantees that collectable liquid sample volume is greater than 0.3mL.The utility model uses vacuum Container utilizes negative pressure absorbing fluid sample as sampling pool.
In the utility model, under original state, it is filled with and does not react with alimentary canal liquid and nothing in needle tubing 104 and conduit 113 Poison liquid, such as atoleine.The volume of filling liquid can be controlled in 1% or less sealing 102 volume of sampling cavity.
The working process of the utility model is as follows: (the capsule when capsule sensor 115 judges that capsule is in sampled targets region Sensor 115 is accurately positioned, and is judged the air-liquid environment of thief hatch neighboring area;Pass through capsule sensor 115 The image of the thief hatch neighboring area of acquisition judges whether thief hatch has residue blocking interference, is conducive to drop using sensor information Low capsule is detained risk), sampled signal is issued, capsule controller 114 adds after being connected to sampled signal to the sending of partition heater 107 Thermal signal, partition heater 107 heat, and soften fusible material fixedly connected part 106, and fracture, spring 110 extends, and drive needle Pipe mounting bracket 105 is translated to 103 direction of sealing-plug, so that the syringe needle of needle tubing 104 is pierced through sealing-plug 103, to make thieff hatch 111, conduit 113, heating fusible conduit 112, needle tubing 104 are connected to sealing sampling cavity 102, and thieff hatch 111 is inhaled using negative pressure Receive fluid sample.Start to sample, can be completed within several seconds.State when sampling is shown in Fig. 2.
Liquid 201 enters along the direction of the arrow in sealing sampling cavity 102 in alimentary canal.Needle tubing 104 stretches out to the right one section, adds Hot fusible conduit 112 becomes one section of fluid flow paths, while rubber sleeve 108 remains closed state, guarantees liquid It will not leak.
(order can be terminated by preset timer determination or external send) after sampling, the control of capsule controller 114 System heating ring 109 heats, and makes to heat the fusing of fusible conduit 112, obstruction heating fusible conduit 112.If heating ring 109 to heat Stop after the dry second, hot fusible conduit 112 solidifies again, blocks fluid flow paths, plays the purpose of closing sampling cavity.Sampling Pond closed state is shown in Fig. 3.
The content that this specification is not described in detail belongs to the prior art well known to professional and technical personnel in the field.

Claims (10)

1. one kind can automatic-sealed sampling capsule endoscope, it is characterised in that: it includes capsule housing (101), sealing-plug (103), needle tubing (104), partition heater (107), heating ring (109), spring (110), heating fusible conduit (112), glue Capsule controller (114), capsule sensor (115), capsule support plate (117) and needle tubing mounting bracket (105), wherein capsule shells Body (101) include control panel chamber (118), acquisition device chamber (116) and sealing sampling cavity (102), control panel chamber (118) with Acquisition device chamber (116) is separated by capsule support plate (117), and acquisition device chamber (116) and sealing sampling cavity (102) are by sealing-plug (103) it separates, capsule housing (101) side wall is equipped with thieff hatch (111), and capsule controller (114) and capsule sensor (115) are set In control panel chamber (118), partition heater (107) is fixed on acquisition device chamber (116) inner wall, spring (110) both ends point It is not fixed on partition heater (107) and needle tubing mounting bracket (105), the pipe shaft of needle tubing (104) is fixed on needle tubing installation branch In the through-hole of frame (105), needle tubing (104) syringe needle is inserted into sealing-plug (103), and capsule support plate (117) is equipped with abutment sleeve (119), the middle through-hole (120) of partition heater (107) is fixedly connected with abutment sleeve (119) outer ring, abutment sleeve (119) Inner ring installation heating ring (109), interior setting heating fusible conduit (112) of heating ring (109), the connector position of needle tubing (104) It is interior in heating fusible conduit (112), and can be under the drive of needle tubing mounting bracket (105) in heating fusible conduit (112) Interior translation, the connector of needle tubing (104) are connected to by heating fusible conduit (112) with thieff hatch (111), needle tubing mounting bracket (105) bottom end is fixedly connected by fusible material fixedly connected part (106) with partition heater (107), control panel chamber (118) side wall is additionally provided with the sensor detection window (122) being arranged side by side with thieff hatch (111), capsule sensor (115) sensing Head is sealingly mounted in sensor detection window (122);
The signal input part of signal output end connection capsule controller (114) of capsule sensor (115), capsule controller (114) two temperature signal output ends are separately connected heating ring (109) and the thermal control signals of partition heater (107) are defeated Enter end.
2. it is according to claim 1 can automatic-sealed sampling capsule endoscope, it is characterised in that: the heating ring (109) inner ring also covers rubber sleeve (108), inner ring of the connection muzzle of needle tubing (104) in rubber sleeve (108), the heating Fusible conduit (112) is located between rubber sleeve (108) and capsule support plate (117);Capsule support plate (117), which offers, to be used for The conduit (113) for being connected to thieff hatch (111) with the connector of needle tubing (104).
3. it is according to claim 1 can automatic-sealed sampling capsule endoscope, it is characterised in that: the sealing-plug (103) side towards sealing sampling cavity (102) is equipped with the raised protective layer (121) opposite with the syringe needle of needle tubing (104).
4. it is according to claim 1 can automatic-sealed sampling capsule endoscope, it is characterised in that: the fusible material is solid The fusing-off temperature for determining connector (106) is 45~50 DEG C.
5. it is according to claim 1 can automatic-sealed sampling capsule endoscope, it is characterised in that: the heating fusible The conduit fusing seal temperature of conduit (112) is 60~90 DEG C.
6. it is according to claim 1 can automatic-sealed sampling capsule endoscope, it is characterised in that: the fusible material is solid Determine connector (106) to fuse after the raising of partition heater (107) temperature, spring (110) elongation drives needle tubing mounting bracket (105) it is translated to sealing-plug (103) direction, so that the syringe needle of needle tubing (104) is pierced through sealing-plug (103), to make thieff hatch (111), conduit (113), heating fusible conduit (112), needle tubing (104) are connected to sealing sampling cavity (102).
7. it is according to claim 1 or 6 can automatic-sealed sampling capsule endoscope, it is characterised in that: the heating can Fusing conduit (112) fuses after the raising of partition heater (107) temperature, heating fusible conduit (112) closing, needle tubing (104) it is closed between conduit (113).
8. it is according to claim 1 or 4 can automatic-sealed sampling capsule endoscope, it is characterised in that: the meltable material Expect that fixedly connected part (106) are the low-melting alloy of nylon yarn, hot melt adhesive or melting range at 45~50 DEG C.
9. according to claim 1 or 5 can automatic-sealed sampling capsule endoscope, it is characterised in that: the heating can The material of fusing conduit (112) is ethylene-vinyl acetate copolymer or POE plastics or solid paraffin.
10. it is according to claim 1 can automatic-sealed sampling capsule endoscope, it is characterised in that: capsule sensing Device (115) is used to obtain the environmental information around thieff hatch (111), and capsule controller (114) is used for the thieff hatch according to acquisition (111) environmental information around is accurately positioned thieff hatch (111), and judges the air-liquid ring in thieff hatch (111) region Border.
CN201820928116.5U 2018-06-15 2018-06-15 Can automatic-sealed sampling capsule endoscope Withdrawn - After Issue CN208973791U (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108784634A (en) * 2018-06-15 2018-11-13 安翰光电技术(武汉)有限公司 Can automatic-sealed sampling capsule endoscope
CN111481236A (en) * 2020-04-15 2020-08-04 杭州憶盛医疗科技有限公司 Alimentary canal liquid biopsy sampling device for internal medicine
CN113116397A (en) * 2019-12-30 2021-07-16 上海科罡医疗技术有限公司 Esophageal wall cell sampler
CN114052798A (en) * 2021-11-11 2022-02-18 安翰科技(武汉)股份有限公司 Sampling capsule

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108784634A (en) * 2018-06-15 2018-11-13 安翰光电技术(武汉)有限公司 Can automatic-sealed sampling capsule endoscope
CN108784634B (en) * 2018-06-15 2023-08-04 安翰科技(武汉)股份有限公司 Sampling capsule endoscope capable of being automatically sealed
CN113116397A (en) * 2019-12-30 2021-07-16 上海科罡医疗技术有限公司 Esophageal wall cell sampler
CN111481236A (en) * 2020-04-15 2020-08-04 杭州憶盛医疗科技有限公司 Alimentary canal liquid biopsy sampling device for internal medicine
CN114052798A (en) * 2021-11-11 2022-02-18 安翰科技(武汉)股份有限公司 Sampling capsule
CN114052798B (en) * 2021-11-11 2024-02-13 安翰科技(武汉)股份有限公司 sampling capsule

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