CN208969107U - A kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation - Google Patents
A kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation Download PDFInfo
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- CN208969107U CN208969107U CN201821780441.8U CN201821780441U CN208969107U CN 208969107 U CN208969107 U CN 208969107U CN 201821780441 U CN201821780441 U CN 201821780441U CN 208969107 U CN208969107 U CN 208969107U
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- 230000011132 hemopoiesis Effects 0.000 title claims abstract description 58
- 238000011156 evaluation Methods 0.000 title claims abstract description 57
- 230000005855 radiation Effects 0.000 title claims abstract description 55
- 230000006378 damage Effects 0.000 title claims abstract description 54
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 73
- 230000001105 regulatory effect Effects 0.000 claims description 27
- 241000397426 Centroberyx lineatus Species 0.000 claims description 4
- 239000013013 elastic material Substances 0.000 claims description 4
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- 239000008280 blood Substances 0.000 abstract description 7
- 238000005516 engineering process Methods 0.000 abstract description 7
- 238000012864 cross contamination Methods 0.000 abstract description 3
- 238000001514 detection method Methods 0.000 description 8
- 238000012360 testing method Methods 0.000 description 7
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- 230000005778 DNA damage Effects 0.000 description 1
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- 101001067891 Homo sapiens Histone H2AX Proteins 0.000 description 1
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- Measurement Of Radiation (AREA)
Abstract
The utility model is suitable for the hematopoiesis of nuclear radiation organism and damages Fast Evaluation field, disclose a kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation, comprising: bottom plate, be relatively arranged on two of the bottom plate both ends connect and fix column, be respectively arranged on two described in connect and fix reagent rack, porous plate and height adjustment device between column；The reagent rack includes the frame body unit of multiple rectangular plate-likes, and the frame body unit is equipped with multiple through accepting hole thereon；The reagent rack further includes frame connection unit that connect two neighboring frame body unit and the groove profile plate for opening upwards；The porous plate is multiple, multiple porous plates setting alternate with multiple frame body units.Compared with the relevant technologies, the utility model can take blood quickly to obtain blood damage Fast Evaluation as a result, overall performance is good on the spot, flexible and convenient to use, can effectively avoid sample cross contamination, precision is high.
Description
Technical field
The utility model belongs to nuclear radiation organism hematopoiesis damage Fast Evaluation field, and in particular to one kind is used for core
The device of irradiating biological body hematopoiesis damage Fast Evaluation.
Background technique
There are many different forms, such as base modification, DNA single-strand breaks for DNA damage
(DNAsinglestrandedbreaks, SSBs), DNA chain is interior to be broken with interchain linkage and DNA double chain
(DNAdoublestrandedbreaks, DSBs) etc., wherein DNA double chain fracture is considered as the damage of DNA most serious.Cell
After sounding DSBs, generates a series of stress reaction and carry out DNA plerosis damage, H2AX is one in a series of this stress reaction
Major Members, it can be expressed as Gamma-H2AX after ATM phosphorylation, and be played in cellular damage repair process later
Important role.Since the appearance of Gamma-H2AX is closely first closed with DSBs, and there is one-to-one relationships, therefore
Gamma-H2AX is also considered as a new specific index of detection cell DNA double-strand break, and therefore causes the country
The extensive concern of outer researchers.Currently, meeting with the device that nuclear radiation causes hematopoiesis damage to lack Fast Evaluation for organism.
In the related technology, by detecting nuclear radiation using detection blood count, spermatoblast detection, cytogenetics detection technique etc.
Damage to body.The deficiency of the relevant technologies is that detection method in the related technology has certain limitation, lacks special
Property, and rely on laboratory and detected, it is unable to reach the purpose for taking blood quickly to obtain testing result on the spot.
Therefore, it is really necessary to provide a kind of new device solution for nuclear radiation organism hematopoiesis damage Fast Evaluation
State technical problem.
Utility model content
The purpose of this utility model is that in view of the above technical problems, the utility model provides a kind of for nuclear radiation biology
The device of body hematopoiesis damage Fast Evaluation, comprising: bottom plate, be relatively arranged on two of the bottom plate both ends connect and fix column, point
Reagent rack, porous plate and the height adjustment device between column She Yu not be connected and fixed described in two；The reagent rack includes multiple
The frame body unit of rectangular plate-like, the frame body unit are equipped with multiple through accepting hole thereon；The reagent rack is also wrapped
Include the two neighboring frame body unit of connection and the groove profile plate for opening upwards frame connection unit；The porous plate is more
It is a, the setting alternate with multiple frame body units of multiple porous plates.Compared with the relevant technologies, the utility model can be on the spot
Blood is taken quickly to obtain blood damage Fast Evaluation as a result, overall performance is good, it is flexible and convenient to use, it can effectively avoid sample cross dirty
Dye, precision are high.
The technical solution of the utility model
In order to solve the above technical problems, a kind of damage for the hematopoiesis of nuclear radiation organism provided by the utility model is quickly commented
The device of valence, comprising: bottom plate, the left side for being relatively arranged on the bottom plate both ends connect and fix column and the right side connects and fixes column, sets respectively
Column is connected and fixed in the left side and the right side connects and fixes reagent rack and porous plate between column；The reagent rack includes multiple squares
The frame body unit of shape plate, the frame body unit are equipped with multiple through accepting hole thereon；The reagent rack further includes
Connect two neighboring frame body unit and the groove profile plate for opening upwards frame connection unit；The porous plate be it is multiple,
The setting alternate with multiple frame body units of multiple porous plates, and the lower part of the porous plate is by the frame connection unit
Support, the porous plate is formed equipped with multiple recess and spaced accommodating hole；The left side connects and fixes column and the right side
It connects and fixes and is equipped with reagent rack card slot at the respective heights of inside opposite on column, the reagent rack card slot is set in the horizontal direction
It sets, the both ends of the frame body unit are arranged in the reagent rack card slot；The left side connects and fixes column and the right clamping is solid
The porous plate card slot being arranged along the vertical direction is additionally provided on the relative position of fixed column, the both ends of each porous plate are equipped with and institute
The corresponding card body of shape of porous plate card slot is stated, the card body is contained in the porous plate card slot；The right side connects and fixes column
It is equipped with regulating device mounting hole, the regulating device mounting hole is the quantity phase of multiple and its quantity and the frame body unit
Together, the regulating device mounting hole connects and fixes the side far from the reagent rack of column to close to the reagent rack from the right side
Direction connect and fix column through the right side, the regulating device mounting hole is rectangle or long waist shaped hole, the regulating device
The length of mounting hole is consistent to the short transverse for connecting and fixing column with the right side；It is described quick for nuclear radiation organism hematopoiesis damage
The device of evaluation further includes height adjustment device, and the height adjustment device is multiple and its quantity and the frame body unit
Quantity is identical, and one end of the height adjustment device is set to the lower section of the frame body unit, the height adjustment device it is another
One end passes through the regulating device mounting hole and is fixed on the right side and connects and fixes on column, in which: the height adjustment device packet
It includes: connecting screw, trigger piece, fastener, fastening nut, rectangular bottom bracing plate and the bolster being covered on above the bottom bracing plate,
One end of the connecting screw is fixedly linked with the bottom bracing plate, and the other end of the connecting screw is pacified through the regulating device
Dress hole is simultaneously arranged the fastening nut；The fastener is fixed on the connecting screw, and the fastener and the fastening nut
Inner sidewall and lateral wall that the right side connects and fixes column are abutted respectively；The trigger piece is set to the separate bottom of the connecting screw
One end of fagging, and the upper and lower surface of the trigger piece is cambered surface made of recess.
Further, the position of the porous plate card slot and the frame body unit mutually staggers.
Further, the width of the frame connection unit is less than the width of the frame body unit.
Further, frame connection unit there are two being set between the adjacent frame body unit, two frame connection units
Interval setting.
Further, the cross-sectional shape of the porous plate card slot is swallow-tail form.
Further, the device for nuclear radiation organism hematopoiesis damage Fast Evaluation further includes limit plunger, described
Limit plunger includes the plug main unit filled in connection unit and be symmetrically set in the plug connection unit both ends, the plug main unit packet
The chock plug being fixedly linked and plug handle are included, two chock plugs connect and fix column by the left side respectively and the right side connects and fixes column
Side in the same direction is caught in the one end in the reagent rack card slot and abutting the frame body unit.
Further, the contact position of the chock plug and the plug handle is step-like.
Further, the limit plunger is made of elastic material.
Further, the limit plunger is made of rubber material.
Further, the device for nuclear radiation organism hematopoiesis damage Fast Evaluation further includes reagent lid, described
Reagent lid and the bottom plate are clamped, and the side close to the bottom plate of the reagent lid, which is equipped with to the direction close to the bottom plate, prolongs
The beading stretched, the beading is two and a left side described in face connects and fixes column respectively and the right side connects and fixes column setting, and two
A beading abuts the top of two card bodies of the porous board ends respectively；The beading is contacted with the card body
Face on coat rubber mat.
Compared with the relevant technologies, the beneficial effects of the utility model are as follows:
(1) in a kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation of the utility model, frame connection unit
It is connect with frame body unit, reagent rack is made to form integral structure, be conducive to whole assembly and disassembly, while be conducive to the utility model one kind and being used for
Nuclear radiation organism hematopoiesis damages the overall stability of the device of Fast Evaluation, avoids using middle shaking.It is set on frame connection unit
Porous plate, frame connection unit is narrower than frame body unit when design, can so reduce the contact area of frame connection unit and porous plate,
Card can be wrapped and stablize support porous plate, while being conducive to entirety loss of weight.Conducive to taking blood quickly to obtain testing result on the spot.
(2) it uses and connects and fixes in a kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation of the utility model
Structure, overall performance is good, and easy to use and flexible.Specifically: it reagent rack and connects and fixes between column as clamping fixation structure；
It porous plate and connects and fixes between column as clamping fixation structure；It is clamping fixation structure between reagent rack and bottom plate.More specifically,
Reagent rack is structure as a whole, and overall performance is good；Porous plate is separate structure and is clamped with column is connected and fixed, and can meet different surveys
Examination amount；It is clamped between reagent rack and bottom plate, can effectively compress porous plate, guarantee monolithic stability and avoid the shadow of outer bound pair reagent
It rings, conducive to the precision for improving testing result.
(3) reagent rack and porous plate in a kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation of the application
Interval setting, can effectively avoid sample cross contamination, conducive to the precision for improving testing result.
(4) more set height are equipped in a kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation of the utility model
Regulating device can adjust the position of every set height adjustment device respectively, meet the application one kind for the hematopoiesis of nuclear radiation organism
It damages in the device of Fast Evaluation and places the demand of the reagent bottle of different height.
A kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation of the utility model, the application one kind are used for core
The device of irradiating biological body hematopoiesis damage Fast Evaluation can be used for suspension cell, attached cell human peripheral monokaryon granulocyte and group
Knit the detection of slice equal samples.It damages Fast Evaluation, energy in nuclear radiation organism hematopoiesis using Gamma-H2AXELISA method
Quickly and effectively detection nuclear radiation damages the hematopoiesis of organism.It is damaged using the application one kind for the hematopoiesis of nuclear radiation organism
Hurt the secondary antibody that the porous plate in the device of Fast Evaluation embeds capture Gamma-H2AX antibody and goat anti-mouse HRP marked price in advance,
Can be detected sample using the metachromasia that chemiluminescent substrate generates, whether there is or not meet with nuclear radiation injury.
Detailed description of the invention
It will be apparent and more hold by made detailed description, the above-mentioned advantage of the utility model in conjunction with the following drawings
Readily understood, these attached drawings are only schematical, are not intended to limit the utility model, in which:
Fig. 1 is a kind of the integrally-built of device that Fast Evaluation is damaged for nuclear radiation organism hematopoiesis of the utility model
The schematic cross-sectional view of main view；
Fig. 2 is a kind of the integrally-built of device that Fast Evaluation is damaged for nuclear radiation organism hematopoiesis of the utility model
Schematic top plan view (after removal reagent lid)；
Fig. 3 is a kind of the whole of height adjustment device that Fast Evaluation is damaged for nuclear radiation organism hematopoiesis of the utility model
Body structural schematic diagram；
Fig. 4 is a kind of stereochemical structure for the reagent rack that Fast Evaluation is damaged for nuclear radiation organism hematopoiesis of the utility model
Schematic diagram.
In figure:
Bottom plate 1, a left side connect and fix column 021, and the right side connects and fixes column 022, reagent rack 3, porous plate 4, limit plunger 5, reagent lid
6, height adjustment device 7；Reagent rack card slot 21, porous plate card slot 22, regulating device mounting hole 23；Frame body unit 31, frame connect
Order member 32；Accommodating hole 41, card body 42；Connection unit 51 is filled in, main unit 52 is filled in；Beading 61, rubber mat 62；Connecting screw 71,
Trigger piece 72, fastener 73, fastening nut 74, bottom bracing plate 75, bolster 76；Accepting hole 311；Chock plug 521 fills in handle 522.
Specific embodiment
It is fast for nuclear radiation organism hematopoiesis damage to one kind of the utility model with attached drawing combined with specific embodiments below
The device of speed evaluation is described in detail.
The embodiment recorded herein is the specific specific embodiment of the utility model, for illustrating the utility model
Design, be it is explanatory and illustrative, should not be construed as the limit to the utility model embodiment and the scope of the utility model
System.In addition to the embodiment recorded herein, those skilled in the art can also be public based on the claim of this application book and specification institute
For the content opened using obvious other technical solutions, these technical solutions include using doing to the embodiment recorded herein
The technical solution of any obvious substitutions and modifications out.
The attached drawing of this specification is schematic diagram, aids in illustrating the design of the utility model, it is schematically indicated each section
Shape and its correlation.It note that for the ease of clearly showing the structure of each component of the utility model embodiment, phase
Same reference marker is for indicating identical part.
Referring to attached drawing 1-4, a kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation, comprising: bottom plate 1, phase
Column 021 connected and fixed to the left side for being set to 1 both ends of bottom plate and the right side connects and fixes column 022, is respectively arranged on a left side and connects and fixes 021 and of column
The right side connects and fixes reagent rack 3 and porous plate 4 between column 022；Reagent rack 3 includes the frame body unit 31 of multiple rectangular plate-likes,
Frame body unit 31 is equipped with multiple through accepting hole 311 thereon；Reagent rack 3 further includes connecting two neighboring frame body unit
31 and for opening upwards groove profile plate frame connection unit 32；Porous plate 4 is multiple, multiple porous plates 4 and multiple frame masters
The alternate setting of body unit 31, and the lower part of porous plate 4 is supported by frame connection unit 32, porous plate 4 is equipped with multiple be recessed
And spaced accommodating hole 41；A left side connects and fixes column 021 and the right side connects and fixes at the respective heights of inside opposite on column 022
Equipped with reagent rack card slot 21, reagent rack card slot 21 is horizontally disposed, and the both ends of frame body unit 31 are arranged in reagent rack card
In slot 21；A left side connect and fix be additionally provided on column 021 and the right relative position for connecting and fixing column 022 be arranged along the vertical direction it is porous
The both ends of board slot 22, each porous plate 4 are equipped with card body 42 corresponding with the shape of porous plate card slot 22, and card body 42 is contained in more
In orifice plate card slot 22；The right side connects and fixes column 022 equipped with regulating device mounting hole 23, and regulating device mounting hole 23 is multiple and it
Quantity is identical as the quantity of frame body unit 31, and regulating device mounting hole 23 is by the right separate reagent rack 3 for connecting and fixing column 022
Side connects and fixes column 022 through the right side to the direction close to reagent rack 3, and regulating device mounting hole 23 is rectangle or long waist shaped
The length in hole, regulating device mounting hole 23 is consistent to the short transverse of column 022 is connected and fixed with the right side；The application one kind is used for nuclear radiation
The device of organism hematopoiesis damage Fast Evaluation further includes height adjustment device 7, height adjustment device 7 be multiple and its quantity with
The quantity of frame body unit 31 is identical, and one end of height adjustment device 7 is set to the lower section of frame body unit 31, height adjustment device
7 other end passes through regulating device mounting hole 23 and is fixed on the right side and connects and fixes on column 022, in which: height adjustment device 7 wraps
It includes: connecting screw 71, trigger piece 72, fastener 73, fastening nut 74, rectangular bottom bracing plate 75 and being covered on the top of bottom bracing plate 75
Bolster 76, one end and the bottom bracing plate 75 of connecting screw 71 are fixedly linked, and the other end of connecting screw 71 is pacified through regulating device
Dress hole 23 is simultaneously arranged fastening nut 74；Fastener 73 is fixed on connecting screw 71, and fastener 73 and fastening nut 74 abut respectively
The right side connects and fixes the inner sidewall and lateral wall of column 022；Trigger piece 72 is set to one end of the separate bottom bracing plate 75 of connecting screw 71, and pulls
The upper and lower surface of handle 72 is cambered surface made of recess.Porous plate card slot 22 and the position of frame body unit 31 mutually stagger.Frame
The width of connection unit 32 is less than the width of frame body unit 31.Frame connection unit there are two being set between adjacent frame main unit 31
32, two interval of frame connection unit 32 settings.The cross-sectional shape of porous plate card slot 22 is swallow-tail form.The application one kind is used for core
The device of irradiating biological body hematopoiesis damage Fast Evaluation further includes limit plunger 5, and limit plunger 5 includes plug connection unit 51 and symmetrically sets
Plug main unit 52 in plug 51 both ends of connection unit, plug main unit 52 include the chock plug 521 and plug handle 522 being fixedly linked,
Two chock plugs 521 connect and fix column 021 by a left side respectively and the right side in the same direction for connecting and fixing column 022 is caught in reagent rack card slot 21
One end that is interior and abutting frame body unit 31.The contact position of chock plug 521 and plug handle 522 is step-like.Limit plunger 5 is by elastic material
It is made.Specifically, in this implementation, limit plunger 5 is made of rubber material.The application one kind is damaged for the hematopoiesis of nuclear radiation organism
The device of Fast Evaluation further includes reagent lid 6, and reagent lid 6 and bottom plate 1 are clamped, the side of close the bottom plate 1 of reagent lid 6 equipped with to
The beading 61 extended close to the direction of bottom plate 1, beading 61 is two and a face left side connects and fixes column 021 respectively and the right side connects and fixes
Column 022 is arranged, and two beadings 61 abut the top of two card bodies 42 at 4 both ends of porous plate respectively；Beading 61 with card body 42
Rubber mat 62 is coated on the face of contact.
It should be noted that in the present embodiment, adjusting in order to enable height adjustment device does not cause to interfere to reagent lid 6
Device mounting hole 23 is designed as stepped hole, that is, includes the rectangle or long waist shaped hole of two perforations, and two hole connecting places form step,
It is slightly larger than the outer diameter of connecting screw 71 close to the width in the hole of fastener 73, is passed through convenient for connecting screw 71.Far from fastener 73
Hole width be slightly larger than fastening nut 74 outer diameter, fastening nut 74 abut two hole connecting places step at.
In the present embodiment, accepting hole 311 is for accommodating and fixating reagent bottle.The cross sectional dimensions of chock plug 521 is slightly larger than examination
21 cross sectional dimensions of agent frame card slot is so convenient for effective clamping.It fills in handle 522 and is greater than chock plug 521, i.e. chock plug 521 and plug handle 522
Contact position be it is step-like, which realizes being caught in and extracting for chock plug 521 convenient for hand-held plug handle 522.The cross of porous plate card slot 22
Cross sectional shape is swallow-tail form or "T"-shaped or other shapes, as long as guaranteeing that notch size is less than slot inside dimension, energy anticreep is realized
Clamping.Under the action of the pressing force of beading 61 and rubber mat 62, the application one kind is damaged for the hematopoiesis of nuclear radiation organism
In the process of moving, porous plate 4 will not upward play for the device of Fast Evaluation.Rubber mat 62 is conducive to effectively compress and buffer.Peace
When dress, the card body 42 of porous plate 4 is aligned porous plate card slot 22, a left side is from top to bottom pushed into and connects and fixes column 021 and right clamping admittedly
In fixed column 022, realization is connected and fixed.Reagent rack card slot 21 is rectangular channel, and connects and fixes column 021 and the right side connects and fixes through a left side
One end of column 022, therefore when reagent rack 3 is packed into, the both ends of frame body unit 31 can be aligned reagent rack card slot 21, and by one
End push-in.Porous plate card slot 22 is staggered with 31 position of frame body unit, can effectively avoid interference.In the present embodiment, regulating device
Mounting hole 23 is rectangle or long waist shaped hole, and the length of regulating device mounting hole 23 is to the short transverse for connecting and fixing column 022 with the right side
Unanimously.The purpose of the setting is, guarantees that connecting screw 71 can be moved along the short transverse that the right side connects and fixes column 022, to meet
Different requirement for height.The upper and lower surface of trigger piece 72 is cambered surface made of recess, which is convenient for hand-held stress, it is ensured that rotation
Pine or fastening nut 74.Bottom bracing plate 75 is used to support the bottom of reagent bottle.In use, the bottom of reagent bottle is set to bolster 76
On, bolster 76 is made of elastic material, provides buffer protection for reagent bottle, avoids it impaired.The use of height adjustment device 7
Method is as follows, according to the height of the height adjustment bottom bracing plate 75 of required reagent bottle.When specific adjusting, operator pinches pulls on the other hand
Handle 72, another hand manually or using spanner unscrew locking nut, increase the distance between fastener 73 and fastening nut 74, no
The right side is locked again connects and fixes column 022.Make connecting screw 71 along on regulating device mounting hole 23 at this point, trigger piece 72 can be moved up and down
After being parked in required height and position, fastening nut 74 is locked for lower movement, will using the pressing force of fastener 73 and fastening nut 74
Height adjustment device 7 is fixed on the right side and connects and fixes on column 022.Each 31 lower section of frame body unit corresponds to a set of height adjustment dress
7 are set, therefore, the position of height adjustment device 7 can be adjusted respectively, meets the application one kind and is damaged for the hematopoiesis of nuclear radiation organism
The demand of the reagent bottle of different height is placed in the device of Fast Evaluation.
Compared with the relevant technologies, the beneficial effects of the utility model are as follows:
(1) in a kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation of the utility model, frame connection unit
It is connect with frame body unit, reagent rack is made to form integral structure, be conducive to whole assembly and disassembly, while be conducive to the utility model one kind and being used for
Nuclear radiation organism hematopoiesis damages the overall stability of the device of Fast Evaluation, avoids using middle shaking.It is set on frame connection unit
Porous plate, frame connection unit is narrower than frame body unit when design, can so reduce the contact area of frame connection unit and porous plate,
Card can be wrapped and stablize support porous plate, while being conducive to entirety loss of weight.The environment extremely unstable suitable for battlefield etc., conducive to taking on the spot
Blood quickly obtains testing result.
(2) it uses and connects and fixes in a kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation of the utility model
Structure, overall performance is good, and easy to use and flexible.Specifically: it reagent rack and connects and fixes between column as clamping fixation structure；
It porous plate and connects and fixes between column as clamping fixation structure；It is clamping fixation structure between reagent rack and bottom plate.More specifically,
Reagent rack is structure as a whole, and overall performance is good；Porous plate is separate structure and is clamped with column is connected and fixed, and can meet different surveys
Examination amount；It is clamped between reagent rack and bottom plate, can effectively compress porous plate, guarantee monolithic stability and avoid the shadow of outer bound pair reagent
It rings, conducive to the precision for improving testing result.
(3) reagent rack and porous plate in a kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation of the application
Interval setting, can effectively avoid sample cross contamination, conducive to the precision for improving testing result.
(4) more set height are equipped in a kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation of the utility model
Regulating device can adjust the position of every set height adjustment device respectively, meet the application one kind for the hematopoiesis of nuclear radiation organism
It damages in the device of Fast Evaluation and places the demand of the reagent bottle of different height.
A kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation of the utility model can be used for suspension cell, patch
The detection of parietal cell human peripheral monokaryon granulocyte and histotomy equal samples.It is using Gamma-H2AX ELISA method in core
Irradiating biological body hematopoiesis damages Fast Evaluation, can quickly and effectively detect nuclear radiation and the hematopoiesis of organism is damaged.
It is using the method that the device of the application carries out nuclear radiation organism hematopoiesis damage Fast Evaluation, it will be more in device
The secondary antibody that embedding capture Gamma-H2AX antibody and goat anti-mouse HRP mark the price in advance of orifice plate 4, utilizes chemiluminescent substrate to generate
Metachromasia can be detected sample, and whether there is or not meet with nuclear radiation injury.
The utility model is not limited to above embodiment, anyone can obtain other under the enlightenment of the utility model
Various forms of products, however, make any variation in its shape or structure, it is all with identical or similar to the present application
Technical solution, all fall within the protection scope of the utility model.
Claims (10)
1. a kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation characterized by comprising bottom plate is set relatively
The left side for being placed in the bottom plate both ends connects and fixes column and the right side connects and fixes column, is respectively arranged on the left side and connects and fixes column and the right side
Connect and fix the reagent rack and porous plate between column；The reagent rack includes the frame body unit of multiple rectangular plate-likes, the frame
Main unit is equipped with multiple through accepting hole thereon；The reagent rack further include connect two neighboring frame body unit and
For the frame connection unit of the groove profile plate of opening upwards；The porous plate is multiple, multiple porous plates and multiple framves
The alternate setting of main unit, and the lower part of the porous plate is supported by the frame connection unit, the porous plate is equipped with multiple
Recess forms and spaced accommodating hole；The left side connects and fixes column and the right side connects and fixes pair of inside opposite on column
It should highly locate to be equipped with reagent rack card slot, the reagent rack card slot is horizontally disposed, and the both ends card of the frame body unit is set
In in the reagent rack card slot；The left side connects and fixes column and the right side connects and fixes and is additionally provided on the relative position of column along vertical
The both ends of the porous plate card slot of direction setting, each porous plate are equipped with card corresponding with the shape of the porous plate card slot
Body, the card body are contained in the porous plate card slot；The right side connects and fixes column equipped with regulating device mounting hole, the tune
Regulating device mounting hole is that multiple and its quantity is identical as the quantity of the frame body unit, and the regulating device mounting hole is by described
The side far from the reagent rack that the right side connects and fixes column connects and fixes column through the right side to the direction close to the reagent rack,
The regulating device mounting hole is rectangle or long waist shaped hole, and the length of the regulating device mounting hole is connected and fixed to the right side
The short transverse of column is consistent；The device for nuclear radiation organism hematopoiesis damage Fast Evaluation further includes height adjustment dress
It sets, the height adjustment device is that multiple and its quantity is identical as the quantity of the frame body unit, the height adjustment device
One end be set to the lower section of the frame body unit, the other end of the height adjustment device passes through the regulating device mounting hole
And it is fixed on the right side and connects and fixes on column, in which: the height adjustment device includes: connecting screw, trigger piece, fastener, fastening
Nut, rectangular bottom bracing plate and the bolster being covered on above the bottom bracing plate, one end of the connecting screw and the bottom
Fagging is fixedly linked, and the other end of the connecting screw through the regulating device mounting hole and is arranged the fastening nut；Institute
It states fastener to be fixed on the connecting screw, and the fastener and the fastening nut abut the right side respectively and connect and fix column
Inner sidewall and lateral wall；The trigger piece is set to one end far from the bottom bracing plate of the connecting screw, and the trigger piece is upper
Lower surface is cambered surface made of recess.
2. the device according to claim 1 for nuclear radiation organism hematopoiesis damage Fast Evaluation, which is characterized in that institute
It states porous plate card slot and the position of the frame body unit mutually staggers.
3. the device according to claim 2 for nuclear radiation organism hematopoiesis damage Fast Evaluation, which is characterized in that institute
The width for stating frame connection unit is less than the width of the frame body unit.
4. the device according to claim 3 for nuclear radiation organism hematopoiesis damage Fast Evaluation, which is characterized in that phase
It is set between the adjacent frame body unit there are two frame connection unit, two frame connection unit intervals are arranged.
5. the device according to claim 4 for nuclear radiation organism hematopoiesis damage Fast Evaluation, which is characterized in that institute
The cross-sectional shape for stating porous plate card slot is swallow-tail form.
6. the device according to claim 1-5 for nuclear radiation organism hematopoiesis damage Fast Evaluation, special
Sign is that the device for nuclear radiation organism hematopoiesis damage Fast Evaluation further includes limit plunger, and the limit plunger includes
Plug connection unit and the plug main unit for being symmetrically set in the plug connection unit both ends, the plug main unit includes being fixedly linked
Chock plug and plug handle, two chock plugs connect and fix column by the left side respectively and the right side connects and fixes the side in the same direction of column
It is caught in the reagent rack card slot and abuts one end of the frame body unit.
7. the device according to claim 6 for nuclear radiation organism hematopoiesis damage Fast Evaluation, which is characterized in that institute
It is step-like for stating the contact position of chock plug and the plug handle.
8. the device according to claim 7 for nuclear radiation organism hematopoiesis damage Fast Evaluation, which is characterized in that institute
Limit plunger is stated to be made of elastic material.
9. the device according to claim 8 for nuclear radiation organism hematopoiesis damage Fast Evaluation, which is characterized in that institute
Limit plunger is stated to be made of rubber material.
10. the device according to claim 9 for nuclear radiation organism hematopoiesis damage Fast Evaluation, which is characterized in that
The device for nuclear radiation organism hematopoiesis damage Fast Evaluation further includes reagent lid, the reagent lid and the backplane card
It connects, the side close to the bottom plate of the reagent lid is equipped with the beading extended to the direction close to the bottom plate, the beading
For two and a left side described in face connects and fixes column respectively and the right side connects and fixes column setting, and two beadings abut respectively
The top of two card bodies of the porous board ends；Rubber mat is coated on the face of the beading contacted with the card body.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821780441.8U CN208969107U (en) | 2018-10-31 | 2018-10-31 | A kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821780441.8U CN208969107U (en) | 2018-10-31 | 2018-10-31 | A kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208969107U true CN208969107U (en) | 2019-06-11 |
Family
ID=66764842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821780441.8U Expired - Fee Related CN208969107U (en) | 2018-10-31 | 2018-10-31 | A kind of device for nuclear radiation organism hematopoiesis damage Fast Evaluation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208969107U (en) |
-
2018
- 2018-10-31 CN CN201821780441.8U patent/CN208969107U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190611 |