CN208958420U - Personalized 3D printing lacrimal stent - Google Patents
Personalized 3D printing lacrimal stent Download PDFInfo
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- CN208958420U CN208958420U CN201821176446.XU CN201821176446U CN208958420U CN 208958420 U CN208958420 U CN 208958420U CN 201821176446 U CN201821176446 U CN 201821176446U CN 208958420 U CN208958420 U CN 208958420U
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- lacrimal
- draught line
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- lacrimal passage
- lachrymal sac
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Abstract
The utility model relates to a kind of personalized 3D printing lacrimal stents, and the 3D printing lacrimal stent includes lachrymal sac support portion, draught line fixed part, nasolacrimal duct lacrimal passage body portion；The lachrymal sac support portion includes draught line outlet, lachrymal sac support portion trunk；The draught line fixed part includes draught line import, traction trajectory；The nasolacrimal duct lacrimal passage body portion includes expansible lacrimal passage body portion, unidirectional closed water inlet；The draught line fixed part front end is conoid；The expansible lacrimal passage body portion is hollow tube；Lachrymal sac support portion, draught line fixed part and the nasolacrimal duct lacrimal passage body is the integral structure of 3D printing.Its advantage is shown: according to patient's examination of lacrimal passages result, in conjunction with 3D printing technique, by driving in the wrong direction the indwelling of Lacrimal passage tube technology in nose lacrimal passage pipe, lachrymal sac support zone in lachrymal sac fixed function, the function that can be conducive to take exercise the sphincter of lacrimal passage by the thickness of bracket simultaneously, reduces the recurrence rate of the postoperative obstruction of lacrimal passage of Lacrimal passage tube.
Description
Technical field
The utility model relates to the field of medical instrument technology that ophtalmic treatments use, specifically, being a kind of personalization 3D
Print lacrimal stent.
Background technique
Lacrimal Passage Block (1acrimal duct obstruction diseases, LDOD), is that ophthalmology is common
Lacrimal apparatus disease, main clinic symptoms show as excessive tear, are mainly in adult female and the middle-aged and the old, can be with frequent, foreign matter of twinkling
Sense, blurred vision etc..Long-term excessive tear is easy to cause the flora imbalance of ocular, the chronic eyes such as conjunctivitis, keratitis, blear-eye occurs
Section's disease seriously affects the quality of life of patient.Obstruction of lacrimal passage is primarily referred to as tear from lacrimal point, lacrimal, lachrymal sac and nasolacrimal duct
The access for being discharged into nasal cavity blocks, and prevents tear from being discharged.It learns according to statistics studies have shown that the case of obstruction of lacrimal canaliculus accounts for
13%, the case of partial blockage below lacrimal accounts for 87%.Current main treatment method mainly takes operative treatment, commonly
Art formula has dacryocystorhinostomy, lacrimal passage drilling to cut, and intubation, lacrimal Laser plasty, drive in the wrong direction lacrimal passage lacrimal passage intubation and lacrimal passage pipe
Implantation etc..Wherein reverse Lacrimal passage tube art is the preferred therapeutic modality of obstruction of lacrimal passage disease.Its main feature is that not changing lacrimal passage row
The approach let out does not damage the anatomical structure of lacrimal passage.Retrograde lacrimal stent includes that following advantage (1) operating method is simple, pacifies
Entirely, time saving.(2) intraoperative hemorrhage is few, no pain, and patient is easy-tolerated.(3) do not change original anatomical position, it can be again after bracket obstruction
Other treatment methods are used in secondary merging instead.(4) without skin incision.It is postoperative not stay scar.(5) success rate of operation is high.Lacrimal passage at present
Stand tube is many kinds of, and majority is the production method produced in batch.1. are had the following disadvantages to fail for patient's obstruction of lacrimal passage
Position personalization the lacrimal stent for designing suitable patient.2. the lacrimal stent indwelling of nasolacrimal duct is easy to de- in nasal cavity
It falls.Often it is fixed size in 3 nasolacrimal duct lacrimal stents, the expansion of movable property can not be carried out to lacrimal passage.
3D printing technique it be that one kind based on Computerized three-dimensional digital imaging technology and multi-level continuous printing technique is new
Emerging application technology, principle are using layering processing, are superimposed molding mode and successively increase material and generate 3D entity.With at
Type precision high, reproducible, achievable industrialization production, the diversity of material, advantage of lower cost.Material used in 3D printing
Material is thermoplastic polyurethane elastomer (TPU), has softness, good tensile strength, impact strength resistant of high or low temperature characteristic, mesh
Before be widely used in medical and health industry.
Chinese patent literature: CN201420522940.2, applying date 2014.09.11, patent name are as follows: lacrimal stent.It is public
A kind of lacrimal stent has been opened, it is characterized in that including lacrimal tube body and nasolacrimal duct tube body, the lacrimal tube body and nasolacrimal duct pipe
Body is integral luminal structure, and lacrimal tube body end is solid garden arc-shaped head, and head is equipped with head traction hole, nose tear
The diameter of pipe tube body is greater than the diameter of lacrimal tube body, and the transition of lacrimal tube body and nasolacrimal duct tube body draws equipped with water-drop-shaped
Drug delivery port is flowed, nasolacrimal duct tube body is equipped with hangnail threading hole and bottom adjusts threading hole.The nasolacrimal duct tube body, tear of the utility model
Tubule tube body, hangnail are integrally formed by silica gel material and are made, simple for production, and integral strength is high, long service life.It can be to lacrimal
Tube body, tear general pipeline, nasolacrimal duct play the role of whole support dilating drainage.But the lacrimal stent is big for the diameter of nasolacrimal duct tube body
In the diameter of lacrimal tube body, contraction and diastole lacrimal passage can not be played the role of, and bracket easily generates adhesion with tissue.
Chinese patent literature: CN201310132070.8, applying date 2013.04.17, patent name are as follows: one kind has shape
The preparation method of shape memory function degradable lacrimal passage bracket.The present invention is with lactic acid and dihydric alcohol or lactic acid, glycolic and caprolactone
For the direct copolycondensation method of monomer or with lactide and dihydric alcohol or lactide, glycolide and the synthesis of caprolactone ring-opening polymerisation method
Degradable lower molecular wt polymer, chain extension add nanosized SiO_2, and melt blending, which squeezes out, is made degradable nano composite wood
Material, extrusion molding, it is 0.4~0.6mm that internal diameter, which is made, and outer diameter is 0.8~1.2mm, and length is 55~65mm cylindrical tube,
More than glass transition temperature, it is 0.2~0.4mm that pipe, which is stretched to internal diameter, and outer diameter is 0.5~0.9mm, and length is 75~85mm
Elongated tubular, cooling save to get required product.The lacrimal stent can be used for treating nasolacrimal passage obliteration, after being implanted into lacrimal passage, environment temperature
Degree is higher than its glass transition temperature, and deformation recovery, diameter is thicker, keeps lacrimal stent not easily to fall off, and character is in soft rubber
Glue, patient comfort.But the invention controls the thickness of lacrimal stent by temperature, tends to be lacrimal passage branch when body temperature
The thickness of frame will no longer change, can not diastole lacrimal passage.Puncta, lacrimal, lachrymal sac, the nose that tear arrives are not imitated out in the invention completely
The structure of tear stains.
Chinese patent literature: CN201220065260.3, applying date 2012.02.27, patent name are as follows: a kind of multi-functional
Lacrimal stent.A kind of multi-functional lacrimal stent, including positioning column are disclosed, the lower end of the positioning column is equipped with separator disc, positioning
The upper end of column is equipped with progressive pipe, and the big end of the progressive pipe is connected on positioning column, is connected to locating bar on the small end of progressive pipe,
It is additionally provided with the draining hole being in communication with the outside on progressive pipe, is equipped in separator disc, positioning column and the progressive pipe and is connected to draining hole
Flow-guiding channel.The utility model structure is very simple, and dismounting is very convenient, and performance is very reliable, fixed supporting & stablizing, effectively anti-
Only previous anastomotic adhesion greatly improves the success rate and security reliability of dacryocystorhinostomy operation, clinically has high
Use value.But the lacrimal stent be nasolacrimal duct tube body diameter be greater than lacrimal tube body diameter, can not play contraction and
The effect of diastole lacrimal passage, and bracket easily generates adhesion with tissue.
In conclusion need it is a kind of according to patient's examination of lacrimal passages as a result, in conjunction with 3D printing technique, pass through the Lacrimal passage tube that drives in the wrong direction
Technology indwelling in nose lacrimal passage pipe, lachrymal sac support zone in lachrymal sac fixed function, while can be advantageous by the thickness of bracket
In the function for the sphincter for tempering lacrimal passage, a kind of personalized 3D printing tear of the recurrence rate of the postoperative obstruction of lacrimal passage of Lacrimal passage tube is reduced
Road bracket.
Summary of the invention
The purpose of this utility model be aiming at the shortcomings in the prior art, provide it is a kind of according to patient's examination of lacrimal passages as a result,
In conjunction with 3D printing technique, by driving in the wrong direction the indwelling of Lacrimal passage tube technology in nose lacrimal passage pipe, lachrymal sac support zone in lachrymal sac it is solid
It is set for using, while can be conducive to take exercise the function of the sphincter of lacrimal passage by the thickness of bracket, reduce the postoperative lacrimal passage of Lacrimal passage tube
A kind of personalized 3D printing lacrimal stent of the recurrence rate of obstruction.
To achieve the above object, the technical scheme adopted by the utility model is that:
A kind of personalization 3D printing lacrimal stent, the 3D printing lacrimal stent include that lachrymal sac support portion, draught line are solid
Determine portion, nasolacrimal duct lacrimal passage body portion；The lachrymal sac support portion includes draught line outlet, lachrymal sac support portion trunk；The traction
Line fixed part includes draught line import, traction trajectory；The nasolacrimal duct lacrimal passage body portion includes expansible lacrimal passage body portion, unidirectional
Closed water inlet；The draught line outlet is set in the middle part of lachrymal sac support portion trunk；The lachrymal sac support portion trunk two sides are
Smooth arc, more soft flexible；The draught line fixed part front end is conoid；It the draught line import and leads
Lead track is sequentially arranged in draught line fixed part；The expansible lacrimal passage body portion is hollow tube, outer diameter 3mm, internal diameter
For 1.8mm, thickness of pipe wall 1.2mm, long 6cm；The unidirectional closed water inlet is set to expansible lacrimal passage body portion end；Described can
Expansion lacrimal passage body portion front end is connect with draught line fixed part end；In the middle part of the draught line fixed part front end and lachrymal sac support portion
Connection；Lachrymal sac support portion, draught line fixed part and the nasolacrimal duct lacrimal passage body is the integral structure of 3D printing；
As a kind of perferred technical scheme, the 3D printing lacrimal stent further includes draught line.
As a kind of perferred technical scheme, described draught line one end is worn through the draught line import on draught line fixed part
It is pierced by after entering by draught line outlet, the other end is after draught line import penetrates, around the traction being set in draught line fixed part
It after trajectory, is pierced by using after draught line import from draught line outlet, and knots with the other end.
As a kind of perferred technical scheme, there are two the traction trajectories.
As a kind of perferred technical scheme, the lacrimal stent overall length 58cm~73cm.
As a kind of perferred technical scheme, nasolacrimal duct lacrimal passage body portion's thickness of the lacrimal stent is adjustable.
As a kind of perferred technical scheme, the unidirectional closed water inlet is intake by the elastic seal itself of colloid
Mouthful.
As a kind of perferred technical scheme, after the capsula interna support portion enters capsula interna, in flabellum expansion such as umbrella knot
Structure.
As a kind of perferred technical scheme, the lacrimal stent uses thermoplasticity urethane elastomer material.
The utility model advantage is:
1, according to the dacryocystography of patient, personalization adjustment lachrymal sac support portion 1 and expansible lacrimal stent body portion
Size greatly reduces the cost that lacrimal stent establishes mold by 3D printing technique.
2, lachrymal sac support zone plays the role of preventing tear stains from slipping in lachrymal sac in bracket, and traction trajectory can effectively be prevented
Only draught line slips, while lachrymal sac support portion soft flexible, and draught line fixed part front end is conoid, is conducive to break through tear
The narrow part in road improves the success rate of operation, after lachrymal sac support portion enters lachrymal sac, is fixed on lachrymal sac in flabellum expansion such as umbrella
Area keeps the stabilization of bracket.
3, can probe by lacrimal probe from upper puncta, inwardly in retrograde Lacrimal passage tube in lacrimal stent
It is pushed to bone wall of lacrimal fossa, rotation probing needle is inserted into nasolacrimal duct vertically downward, pumps probing needle inner core, and saline injection confirms
Probing success, insertion seal wire tick draught line from nasal cavity with metal wire taking hook to meatus nasi inferior, finally by the effect of draught line,
So that branch is placed on corresponding position in lacrimal passage, after setting pipe and successfully staying in lacrimal passage, wherein single line is cut, it can be easier
Pull out another single line.
4, the nasolacrimal duct pipe portion thickness of lacrimal stent is adjustable, is conducive to the function of tempering lacrimal passage sphincter.
5, by filling the water the contracting nose lacrimal passage tube wall so that the expansion and contraction of lacrimal stent are relaxed, even tending to the tissue of adhesion
Again it loosens, the potential function of lacrimal passage smooth muscle can also be excited, do not easily cause the tissue edema of lacrimal passage, to reinforce the blood of lacrimal passage
For.
6, the design of unidirectional water inflow mouth, it is ensured that the catarrh sexual secretion in nasal cavity is not easy to cause the resistance of the water inlet of bracket
Plug.
Detailed description of the invention
Attached drawing 1 is a kind of general structure schematic diagram of personalized 3D printing lacrimal stent of the utility model.
Attached drawing 2 is a kind of draught line stationary state schematic diagram of personalized 3D printing lacrimal stent of the utility model.
Attached drawing 3 is a kind of use state diagram of personalized 3D printing lacrimal stent of the utility model.
Specific embodiment
It elaborates with reference to the accompanying drawing to specific embodiment provided by the utility model.
Appended drawing reference involved in attached drawing and component part are as follows:
1. 11. draught line of lachrymal sac support portion exports
12. 2. draught line fixed part of lachrymal sac support portion trunk
21. trajectory is drawn in draught line import 22.
23. 3. nasolacrimal duct lacrimal passage body portion of draught line
31. the unidirectional closed water inlet in expansible lacrimal passage body portion 32.
Embodiment 1
Attached drawing 1 is please referred to, Fig. 1 is a kind of general structure schematic diagram of personalized 3D printing lacrimal stent of the utility model.
A kind of personalization 3D printing lacrimal stent, the 3D printing lacrimal stent includes lachrymal sac support portion 1, draught line fixed part 2, nose
Tear stains lacrimal passage body portion 3；The lachrymal sac support portion 1 includes that draught line exports 11, lachrymal sac support portion trunk 12；The draught line
Fixed part 2 includes draught line import 21, traction trajectory 22；The nasolacrimal duct lacrimal passage body portion 3 includes expansible lacrimal passage body portion
31, unidirectional closed water inlet 32；The draught line outlet 11 is set to 12 middle part of lachrymal sac support portion trunk；The lachrymal sac support
Trunk 12 two sides in portion's are smooth arc, more soft flexible；2 front end of draught line fixed part is conoid；It is described
Draught line import 21 and traction trajectory 22 be sequentially arranged in draught line fixed part 2；The expansible lacrimal passage body portion 31 is
Hollow tube, outer diameter 3mm, internal diameter 1.8mm, thickness of pipe wall 1.2mm, long 6cm；The unidirectional closed water inlet 32 is set to can
Expand 31 end of lacrimal passage body portion；32 front end of expansible lacrimal passage body portion is connect with 2 end of draught line fixed part；Described leads
It is connected in the middle part of 2 front end of lead fixed part and lachrymal sac support portion 1；Lachrymal sac support portion 1, draught line fixed part 2 and the nasolacrimal duct
Lacrimal passage body 3 is the integral structure of 3D printing；
Attached drawing 2 is please referred to, Fig. 2 is that a kind of lead stationary state that personalized 3D printing lacrimal stent is led of the utility model shows
It is intended to.The draught line fixed part 2 is additionally provided with draught line 23；Described 23 one end of draught line is through on draught line fixed part 2
Draught line import 21 is pierced by after penetrating by draught line outlet 11, and the other end is led after draught line import 21 penetrates around being set to
After traction trajectory 22 in lead fixed part 2,11 be pierced by using after draught line import 21 from draught line outlet, and with it is another
End knots；
Attached drawing 3 is please referred to, Fig. 3 is a kind of use state diagram of personalized 3D printing lacrimal stent of the utility model.
When the 3D printing lacrimal stent enters patient's lacrimal passage, 1 liang of lateral bend of lachrymal sac support portion is simultaneously affixed on front end conoid structure
2 two sides of draught line fixed part；After lachrymal sac support portion 1 enters patient's lachrymal sac, lachrymal sac is fixed in the expansion of 1 two sides of lachrymal sac support portion
Area.
It should be understood that the 3D printing lacrimal stent overall length 58cm~73cm；The traction trajectory 22 has
Two, draught line 23 can be effectively prevent to slip；The 3D printing lacrimal stent uses thermoplasticity urethane elastomer (TPU) material
Material, has good telescopicing performance, and good biocompatibility is nonirritant to tissue, non-toxic, without allergic reaction, body
Rejection is few；With good physicochemical property, be able to maintain in body fluid and tissue contact process its original elasticity and
Pliability is not degraded, and is a kind of quite stable inert substance；Energy high temperature resistant, can sterilize；Machine-shaping is convenient, easy processing
Shape is carved, it is easy to use；
The 3D printing process of one of the utility model personalization 3D printing lacrimal stent are as follows:
1. the material that will be printed is put into drying box after shredding, 60 DEG C of 4 hours of drying；
2. the material after the completion of drying is put into printing barrel；
3. opening biometric print machine controls software AnyPrint, model is transferred；
4. print parameters is arranged in parameter setting option (shown in the following table of design parameter)；
5. after printing head is preheating to 200 DEG C, clicking direct print button；
6. printing is completed
The following are personalized lacrimal stent 3D printing parameter tables:
| Filling line pattern | Concentric circles |
| Filling | 100% |
| Thickness | 0.2mm |
| Print temperature | 210 |
| Print speed | 10 |
| Sky walks speed | 20 |
| Fan speed | 0 |
| Substructure height | 0.1 |
| Raw silk percentage of cocoon | 120 |
| Nozzle diameter | 0.4 |
| Print syringe needle | 22# |
A kind of personalized 3D printing lacrimal stent of described the utility model, it is personalized according to the dacryocystography of patient
The size in adjustment lachrymal sac support portion 1 and expansible lacrimal stent body portion greatly reduces lacrimal passage branch by 3D printing technique
Frame establishes the cost of mold；Lachrymal sac support portion 1, which is located in lachrymal sac, in the bracket plays the role of preventing tear stains from slipping, traction
Trajectory 22 can effectively prevent draught line 23 to slip, while 1 soft flexible of lachrymal sac support portion, 2 front end of draught line fixed part are
Conoid is conducive to the narrow part for breaking through lacrimal passage, improves the success rate of operation, is in flabellum after lachrymal sac support portion 1 enters lachrymal sac
Expansion such as umbrella is fixed on lachrymal sac area, keeps the stabilization of bracket；Described can lead in retrograde Lacrimal passage tube in lacrimal stent
It crosses lacrimal probe to probe into from upper puncta, is pushed to bone wall of lacrimal fossa inwardly, rotation probing needle is inserted into nose tear vertically downward
Pipe, pumps probing needle inner core, and saline injection confirms probing success, insertion seal wire to meatus nasi inferior, with metal wire taking hook from nose
Chamber ticks draught line 23, successfully stays so that branch is placed on corresponding position in lacrimal passage when setting pipe finally by the effect of draught line 23
After in lacrimal passage, wherein single line is cut, another single line can be easier pulled out；The nasolacrimal duct lacrimal passage of the lacrimal stent
Body portion thickness is adjustable, is conducive to the function of tempering lacrimal passage sphincter；The unidirectional water inflow mouth 32 passes through the elasticity of colloid certainly
Row closing water inlet；It is described by water filling so that the expansion and contraction of lacrimal stent are relaxed contracting nose lacrimal passage tube wall, even tending to
The tissue of adhesion is loosened again, can also be excited the potential function of lacrimal passage smooth muscle, easily not caused the tissue edema of lacrimal passage, thus plus
The blood supply of strong lacrimal passage；The design of the unidirectional water inflow mouth 32, it is ensured that the catarrh sexual secretion in nasal cavity is not easy to cause bracket
Water inlet obstruction.
The above is only the preferred embodiment of the utility model, it is noted that for the common skill of the art
Art personnel can also make several improvement and supplement under the premise of not departing from the utility model method, these are improved and supplement
Also it should be regarded as the protection scope of the utility model.
Claims (9)
1. a kind of personalization 3D printing lacrimal stent, which is characterized in that the 3D printing lacrimal stent include lachrymal sac support portion,
Draught line fixed part, nasolacrimal duct lacrimal passage body portion；The lachrymal sac support portion includes draught line outlet, lachrymal sac support portion trunk；Institute
The draught line fixed part stated includes draught line import, traction trajectory；The nasolacrimal duct lacrimal passage body portion includes expansible lacrimal passage
Body portion, unidirectional closed water inlet；The draught line outlet is set in the middle part of lachrymal sac support portion trunk；The lachrymal sac support portion master
Dry two sides are smooth arc, more soft flexible；The draught line fixed part front end is conoid；The draught line
Import and traction trajectory are sequentially arranged in draught line fixed part；The expansible lacrimal passage body portion is hollow tube, and outer diameter is
3mm, internal diameter 1.8mm, thickness of pipe wall 1.2mm, long 6cm；The unidirectional closed water inlet is set to expansible lacrimal passage body portion end；
The expansible lacrimal passage body portion front end is connect with draught line fixed part end；The draught line fixed part front end and lachrymal sac branch
Connection in the middle part of support part；Lachrymal sac support portion, draught line fixed part and the nasolacrimal duct lacrimal passage body is the integral structure of 3D printing.
2. 3D printing lacrimal stent according to claim 1, which is characterized in that the 3D printing lacrimal stent further includes
Draught line.
3. 3D printing lacrimal stent according to claim 2, which is characterized in that described draught line one end is solid through draught line
Determine to be pierced by after the draught line import in portion penetrates by draught line outlet, the other end is after draught line import penetrates, around being set to
After traction trajectory in draught line fixed part, it is pierced by using after draught line import from draught line outlet, and beaten with the other end
Knot.
4. 3D printing lacrimal stent according to claim 1 or 3, which is characterized in that there are two the traction trajectories.
5. 3D printing lacrimal stent according to claim 1, which is characterized in that the lacrimal stent overall length 58cm~
73cm。
6. 3D printing lacrimal stent according to claim 1, which is characterized in that the nasolacrimal duct lacrimal passage of the lacrimal stent
Body portion thickness is adjustable.
7. 3D printing lacrimal stent according to claim 1, which is characterized in that the unidirectional closed water inlet passes through glue
The elastic seal itself water inlet of body.
8. 3D printing lacrimal stent according to claim 1, which is characterized in that the lachrymal sac support portion enters lachrymal sac
Afterwards, in flabellum expansion such as umbrella-shaped structure.
9. 3D printing lacrimal stent according to claim 1 or 5, which is characterized in that the lacrimal stent uses thermoplastic
Property urethane elastomer material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821176446.XU CN208958420U (en) | 2018-07-24 | 2018-07-24 | Personalized 3D printing lacrimal stent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821176446.XU CN208958420U (en) | 2018-07-24 | 2018-07-24 | Personalized 3D printing lacrimal stent |
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| Publication Number | Publication Date |
|---|---|
| CN208958420U true CN208958420U (en) | 2019-06-11 |
Family
ID=66749081
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| Application Number | Title | Priority Date | Filing Date |
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| CN201821176446.XU Active CN208958420U (en) | 2018-07-24 | 2018-07-24 | Personalized 3D printing lacrimal stent |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109009587A (en) * | 2018-07-24 | 2018-12-18 | 上海市同济医院 | A kind of personalization 3D printing lacrimal stent |
| CN111228034A (en) * | 2020-01-16 | 2020-06-05 | 贵州省人民医院 | Drug-loading controlled-release lacrimal duct embolus and preparation method thereof |
-
2018
- 2018-07-24 CN CN201821176446.XU patent/CN208958420U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109009587A (en) * | 2018-07-24 | 2018-12-18 | 上海市同济医院 | A kind of personalization 3D printing lacrimal stent |
| CN109009587B (en) * | 2018-07-24 | 2023-12-19 | 上海市同济医院 | Personalized 3D prints lacrimal passage support |
| CN111228034A (en) * | 2020-01-16 | 2020-06-05 | 贵州省人民医院 | Drug-loading controlled-release lacrimal duct embolus and preparation method thereof |
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