CN208927393U - A kind of adjustable perfusion system and perfusion conduit - Google Patents

A kind of adjustable perfusion system and perfusion conduit Download PDF

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Publication number
CN208927393U
CN208927393U CN201820360740.XU CN201820360740U CN208927393U CN 208927393 U CN208927393 U CN 208927393U CN 201820360740 U CN201820360740 U CN 201820360740U CN 208927393 U CN208927393 U CN 208927393U
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tube body
lumen
conduit
pressure
adjustable
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陶华
王翔飞
邓晓文
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Abstract

The utility model provides a kind of adjustable perfusion system, and the adjustable perfusion system includes conduit and pressure-regulating device, wherein the conduit includes tube body and lumen;There are multiple side openings, the multiple side opening is adapted so that internal blood flows into the lumen on the tube body;The proximal part of the tube body has proximal end bore, and the proximal end bore is adapted so that extracorporeal liquid flows into the lumen;The distal portions of the tube body have remote stomidium, and the remote stomidium is adapted so that the internal blood and the extracorporeal liquid flow out the lumen;The pressure-regulating device is connected to the proximal end bore, for adjusting the pressure of the extracorporeal liquid.The utility model adjusts the injection pressure of extracorporeal liquid by pressure-regulating device, or the area of open side opening is adjusted by adjusting seal wire, flow into embolic occlusion section distal end perfusion blood flow gradually increase, realize it is gradual excessively, avoid blood flow and restore the damage caused by blood vessel suddenly.

Description

A kind of adjustable perfusion system and perfusion conduit
Technical field
The utility model relates to a kind of medical catheters, more particularly, to a kind of adjustable perfusion system for thrombus With perfusion conduit.
Background technique
Acute arterial embolism is a kind of common disease, and the most familiar is acute myocardial infarction and acute cerebral infarction.It is practical On, all arterial systems are likely to that embolism class diseases occur, and embolus the most common is thrombus, and most thrombus are local originals Because caused by, a small number of thrombus are that the thrombus that remaining place is formed comes along blood flow drift.
The completely plugged artery of acute thrombus (blood flow about 0%), leads to cell hypoxic-ischemic, gradually dead.This is referred to as For ischemic injuries.Occluded blood vessel is opened in time and restores blood flow (blood flow about 100%), can be saved cell in imminent danger, still, also can Promote part survivaling cell dead, this is referred to as reperfusion injury.
Existing Reperfu- sion mode is to restore blood flow by partially disintegrating endarterial thrombus, but they are for blood flow At once the degree restored is impossible to finely regulating.This is because thrombus is collectively formed by a variety of blood constituents, have multiple The characteristics of polygamy and dynamic evolution.Thrombus suction catheter can pump out the thrombus of different proportion, restore blood flow, this ratio is It is uncontrollable.Sacculus pressurization squeezes thrombus, and thrombus is partially compressed, but after sacculus is withdrawn, pressure disappears, itself has elasticity Thrombus can part restore, this ratio is also uncontrollable.Under current this mode, blood vessel amount is restored to 100% from 0% Process be a uncontrollable process.
Numerous results of animal show that reperfusion injury is related with the mode of Reperfu- sion, are restored to suddenly from 0% 100% is harmful.Finding the method that can reduce reperfusion injury has lasted many decades, may currently, there are two types of methods It is feasible.The first, adjusts the controlled reperfusion of blood physical parameter, by controlling the physical parameter of Reperfu- sion, such as temperature, pressure Power, flow, mode etc. realize the gradual transition from 0% to 100%.Second, adjust the controlling of blood chemistry parameter again Perfusion increases the drug of protection cardiac muscle cell such as possible harmful ingredients certain in antagonism blood.Drug can be directly injected into Into the coronary artery for causing problem, this local administration mode can be improved drug concentration and reach better effect, while The systemic side effects that drug can be reduced are ideal selections, far superior to simple through peripheral vein administration mode.
Adjusting the controlled reperfusion of blood the physical-chemical parameters in the prior art mainly includes perfusion balloon catheter, OTW sacculus And thrombus suction catheter.
Perfusion balloon catheter: perfusion balloon catheter refers to there is fill orifice in balloon proximal and distal end, between proximal end bore and remote stomidium There is cavity to be connected, in this way, the blood flow in proximal vessel can still enter the perfusion of proximal end when balloon expandable blocks intravascular blood flow Hole, the fill orifice of distal end is reached by connected cavity, then is flowed into distal vessels, realizes the blood perfusion to distal vessels. Normal level is not achieved in the degree of this part perfusion, still, with the absolutely not blood perfusion the case where compared with, perfusion balloon catheter band The part perfusion come reduces the hypoxic-ischemic degree of patient.The shortcomings that perfusion balloon catheter is that (1) opening diameter is fixed, blood flow Physical parameter be difficult to adjust, or even be not adjustable;(2) it is unable to coronary artery local administration.
Over-the-wire (OTW) sacculus: this is two-chamber bar sacculus, positioned at external tail end of conduit there are two hole, one Hole is identical as sacculus, and can pressurize dilating sacculus, realizes the expansion of sacculus.Another hole is communicated with conductor housing stomidium, this is logical Road both P Passable seal wire, can also pass through tail end hole perfusion liquid into the distal end coronary artery of balloon occlusion after withdrawing seal wire Body (including blood) is partially similar to perfusion balloon catheter.It is main perfusion the difference is that, the hole of sacculus proximal segment is located at conduit tail End, outside body rather than in coronary artery.The shortcomings that OTW sacculus is that tail end perfusion liquid is feasible, can be realized most physics ginsengs The purpose of several and chemical parameters regulation, still, if blood perfusion (final target is still 100% hemoperfusion), mistake Journey is cumbersome.Because blood needs to extract out in vitro, injected in coronary artery using conduit as required, this cumbersome process Activation and red blood cell with blood coagulation system it is broken, increase the risk of reperfusion injury instead.
Thrombus suction catheter: being a kind of single-chamber bar conduit, and head end hole is mostly stomidium, positioned at the head end of conduit, tail end hole Mostly stomidium, positioned at the tail portion of conduit.Compared with OTW sacculus, without balloon system.Usually head end hole is placed near thrombus, The vacuum suction of tail end hole attracts thrombus to enter conduit by head end hole, flows out from tail end hole.Also it can be reversed operation, pass through Liquid is injected in tail end hole, and through conduit, head end hole is flowed into the coronary artery of occlusion section distal end.The shortcomings that thrombus suction catheter with OTW sacculus is similar.In addition, when external tail end enhancing perfusion, head-end flow increases, institute perfusion area because not having balloon system Domain pressure rise, in fact it could happen that occlusion section remote pressure is higher than proximal pressure (proximal pressure pressure in aorta) Possibility, then, thrombus has the risk moved to the near end.
Therefore, it is necessary to a kind of training equipments, it preferably has the physical parameter or chemical parameters for realizing control liquid Ability.Meanwhile being frequently experienced in 1~5 minute in view of reperfusion injury, it must also have the ability that can quickly adjust.
Utility model content
Problem to be solved in the utility model is the Modulatory character of blood perfusion parameter when realizing ischemia-reperfusion.
To solve the above-mentioned problems, the utility model provides a kind of adjustable perfusion system, the adjustable perfusion system Including conduit and pressure-regulating device,
Wherein, the conduit includes tube body and lumen;
There are multiple side openings, the multiple side opening is adapted so that internal blood flows into the lumen on the tube body;
The proximal part of the tube body has proximal end bore, and the proximal end bore is adapted so that extracorporeal liquid flows into the lumen;
The distal portions of the tube body have a remote stomidium, and the remote stomidium is adapted so that the internal blood and described external Liquid flows out the lumen;
The pressure-regulating device is connected to the proximal end bore, for adjusting the pressure of the extracorporeal liquid.
In an embodiment of the utility model, pass through detachable side between the pressure-regulating device and the proximal end bore Formula connection.
In an embodiment of the utility model, the removably includes being threadedly coupled.
In an embodiment of the utility model, the conduit further includes operation guidewire lumen, and the operation guidewire lumen is used for Insertion manipulation seal wire is to guide the conduit to enter thrombi.
It further include the dilatation balloon being attached on tube body in an embodiment of the utility model.
It further include the negative pressure drainage device for being connected to the remote stomidium in an embodiment of the utility model, being used for will The blood drainage of distal portions is to external.
The utility model also provides a kind of adjustable perfusion conduit, the adjustable perfusion conduit include tube body, lumen and Adjust seal wire;
The tube body has multiple side openings, and the multiple side opening is adapted so that internal blood flows into the lumen;
The proximal part of the tube body has proximal end bore, and the adjusting seal wire is suitable for entering the pipe by the proximal end bore Chamber, and when the adjusting seal wire is from the distal portions proximally partial movement of the conduit, so that the opening number of the side opening Mesh gradually increases;
The distal portions of the tube body have remote stomidium, and the remote stomidium is adapted so that the internal blood flows out the pipe Chamber.
In an embodiment of the utility model, the multiple side opening is arranged in a straight line, and the diameter phase of each side opening Together.
In an embodiment of the utility model, the diameter of the multiple side opening is from distally proximally gradually increasing.
It further include the dilatation balloon being attached on tube body in an embodiment of the utility model.
The beneficial effect of technical solutions of the utility model is: compared with prior art, the utility model is adjusted by pressure Device adjusts the injection pressure of extracorporeal liquid, or the area of open side opening is adjusted by adjusting seal wire, flows into embolic occlusion section The perfusion blood flow of distal end gradually increases, realize it is gradual excessively, avoid blood flow and restore the damage caused by blood vessel suddenly.
Detailed description of the invention
It is practical to this below in conjunction with attached drawing for the above objects, features, and advantages of the utility model can be clearer and more comprehensible Novel specific embodiment elaborates, in which:
Fig. 1 is the schematic diagram of the adjustable perfusion system of an embodiment according to the present utility model;
Fig. 2 is schematic diagram of the adjustable perfusion system in thrombi of an embodiment according to the present utility model;
Fig. 3 is the schematic diagram of the adjustable perfusion system of another embodiment according to the present utility model;
Fig. 4 is the schematic diagram of the adjustable perfusion conduit of an embodiment according to the present utility model;
Fig. 5 is schematic diagram of the adjustable perfusion conduit in thrombi of an embodiment according to the present utility model;
Fig. 6 is the schematic diagram of the adjustable perfusion conduit of another embodiment according to the present utility model.
Specific embodiment
It is practical to this below in conjunction with attached drawing for the above objects, features, and advantages of the utility model can be clearer and more comprehensible Novel specific embodiment elaborates.
Many details are explained in the following description in order to fully understand the utility model, but this is practical new Type can also be implemented using other different from other way described herein, therefore the utility model is not by following public tool The limitation of body embodiment.
As shown in the application and claims, unless context clearly prompts exceptional situation, " one ", "one", " one The words such as kind " and/or "the" not refer in particular to odd number, may also comprise plural number.It is, in general, that term " includes " only prompts to wrap with "comprising" Include clearly identify the step of and element, and these steps and element do not constitute one it is exclusive enumerate, method or apparatus The step of may also including other or element.
When liquid flows in pipeline, hydromechanical Poiseuille's law is used to calculate the flow of liquid,
Q=Δ P π r4/8ηl
Wherein Q indicates that the flow of liquid, Δ P indicate the pressure difference at both ends, and r indicates that the cross-sectional area of pipeline, η indicate liquid The coefficient of viscosity, l indicate pipeline length.Therefore the cross-sectional area of flow and pipeline, the pressure difference and liquid property at both ends have It closes, the process of perfusion can be controlled by the pressure difference and the cross-sectional area of pipeline for adjusting pipeline.
Embodiment one
The present embodiment is the system by adjusting the pressure difference control perfusion of pipeline.Fig. 1 is according to the present utility model one The schematic diagram of the adjustable perfusion system 100 of embodiment.Adjustable perfusion system 100 includes conduit 110 and pressure-regulating device 120.Conduit 110 includes tube body 111, lumen 112, multiple side openings 113 and guiding wire chamber 114.
Tube body 111 is preferably shaped to cylinder, to be adapted to the shape of blood vessel, to reduce the loss to blood vessel.Tube body 111 proximal part has proximal end bore 116, and proximal end bore 116 is adapted so that extracorporeal liquid flows into lumen 112 by proximal end bore 116. The distal portions of tube body 111 have remote stomidium 115, and remote stomidium 115 is adapted so that internal blood and extracorporeal liquid pass through remote stomidium 115 outflow lumens 112.Optionally, adjustable perfusion system 100 may also include a negative pressure device (not shown), can be connected to Remote stomidium 115, for the blood flow of embolic occlusion distal end to be drained in vitro, negative pressure device can be vacuum pump or other can produce The device of raw negative pressure.
There are multiple side openings 113 on tube body 111.The position of multiple side openings 113 can be located at the middle section of tube body, Huo Zhezhong Between part close to proximal part or middle section close to distal portions, depending on the length of thrombus.Internal blood passes through multiple Side opening 113 flows into lumen 112.The number of side opening 113 is multiple, preferably 3-5.The diameter of multiple side openings 113 can be identical, It can also be different.Such as aperture is gradually increased from the proximal part distal end portion of tube body 111, or from the proximal end of tube body 111 Part distal end portion is gradually reduced.Multiple side openings 113 can be arranged in a straight line, or be arranged in other arbitrary shapes.
Lumen 112 is the hollow space inside tube body 111.Preferably, the shape one of the shape of lumen 112 and tube body 111 It causes, such as cylindrical.Lumen 112 be it is open, run through entire body portion, and be communicated with the outside.
Pressure-regulating device 120 is connected to the proximal end bore 116 of the proximal part of tube body 111, for adjusting extracorporeal liquid Injection pressure.Pressure-regulating device 120 can be connected releasably to proximal end bore 116, such as be threadedly coupled or engage and connect It connects.
Guiding wire chamber 114 is located at the outer wall of tube body 111, and for penetrating guiding wire, conduit is guided to comprising thrombus Target site.Guiding wire chamber 114 can extend in entire tube body 111, can also extend in the part of tube body 111.Fig. 1 shows The cross section of guiding wire chamber 114 and lumen 112 is gone out, the length of guiding wire chamber 114 is not limited to be only positioned at shown in Fig. 1 The distal portions of conduit 110.It will be seen from figure 1 that the cross section of lumen 112 and guiding wire chamber 114 is all round, and manage The caliber of chamber 112 is significantly larger than the caliber of guiding wire chamber 114.
Fig. 2 is schematic diagram of the adjustable perfusion system 100 in thrombi of embodiment according to the present utility model.Such as figure Shown in 2, conduit 110 enters from the proximal end P (Proximal) of embolic occlusion section, passes through entire thrombus T (Thrombosis), enters The proximal end bore 116 of the distal end D (Distal) of embolic occlusion section, tube body 111 are located in vitro, and multiple side openings 113 of tube body 111 are located at In proximal vessel, the remote stomidium 115 of tube body 111 is located at the distal end of embolic occlusion section.
The working principle of adjustable perfusion system is described below.
By proximal end bore 116 be perfused extracorporeal liquid, pressure-regulating device 120 adjust extracorporeal liquid injection pressure, (a) when When the injection pressure of extracorporeal liquid is more than arterial systolic blood pressure, it is terminated completely by the hemoperfusion that side opening 113 enters conduit, body Outer liquid flows to embolic occlusion section proximally and distally by proximal end bore 116 and side opening respectively, and the two flow is similar, pressure phase The very little when, thrombus is mobile a possibility that.(b) when the pressure of extracorporeal liquid is between systolic pressure and diastolic pressure, internal blood and Extracorporeal liquid alternately enters in conduit, i.e., heart contraction when systolic pressure be more than extracorporeal liquid pressure, blood enters conduit;Heart relaxes Extracorporeal liquid pressure is more than diastolic pressure when opening, and extracorporeal liquid enters conduit, then flows into embolic occlusion section distal end from remote stomidium 115 Artery.If (c) extracorporeal liquid pressure is lower than diastolic pressure, only internal blood enters conduit by side opening 113, from remote The artery of the inflow of stomidium 115 embolic occlusion section distal end.
When beginning, pressure-regulating device 120 applies the injection pressure for being greater than systolic pressure, hemoperfusion to extracorporeal liquid It closes, only the artery of extracorporeal liquid perfusion embolic occlusion section distal end, is then gradually decreased in vitro by pressure-regulating device 120 The injection pressure of liquid, when extracorporeal liquid injection pressure is dropped between systolic pressure and diastolic pressure, extracorporeal liquid and internal blood are handed over For the artery for entering embolic occlusion section distal end, the injection pressure of extracorporeal liquid is further decreased, extracorporeal liquid pressure drops to diastole When under pressure, extracorporeal liquid perfusion is closed, and internal blood enters the artery of embolic occlusion section distal end later.As extracorporeal liquid fills The decline of injection pressure power, flow into blood vessel distal end perfusion blood flow gradually increase, realize it is gradual excessively, it is suddenly extensive to avoid blood flow It is multiple to be damaged caused by blood vessel.
Embodiment two
Fig. 3 is the schematic diagram of the adjustable perfusion system 200 of another embodiment according to the present utility model.Adjustable perfusion System 200 includes conduit 210 and pressure-regulating device 220, and conduit 210 and pressure-regulating device 220 are similar to adjustable perfusion The conduit 110 and pressure-regulating device 120 of system 100, details are not described herein again.
Adjustable perfusion system 200 further includes sacculus 230.Sacculus 230 is attached on tube body 211, spherical in shape or oval. Fig. 3 shows sacculus 230 and is located between side opening 213 and the remote stomidium 215 of tube body 211, but not limited to this, sacculus 230 may be alternatively located at The distal end of side opening 213.Sacculus 230 can be inflatable air bag, air bag can be made to expand by injection liquid or gas, liquid Or gas can be entered inside inflatable air bag by pipeline (not shown), pipeline can be located at the outside of tube body 211, The inside of tube body 211 can be located at, it is preferable that pipeline is located at the inside of tube body 211, to reduce the size of conduit, and then reduces Damage to blood vessel.
When adjustable perfusion system 200 enters thrombi, side opening 213 is located at the proximal end of embolic occlusion section, remote stomidium 215 are located at the distal end of embolic occlusion section, and between side opening 213 and remote stomidium 215, sacculus 230 can close sacculus 230 positioned at thrombus The proximal end of section or the distal end of embolic occlusion section are filled in, after injecting gas or liquid by pipeline, sacculus 230 expands, by embolic occlusion The proximal end of section and the distal end of embolic occlusion section separate, and can preferably block the flowing of blood, can more precisely control blood flow That restores is gradual.
Embodiment three
The present embodiment is the adjustable perfusion conduit that can be perfused by adjusting the cross-sectional area control of pipeline.
Fig. 4 is the schematic diagram of the adjustable perfusion conduit 300 of an embodiment according to the present utility model.Adjustable perfusion is led Pipe 300 includes tube body 310, lumen 320, and side opening 311 adjusts seal wire 330 and seal wire guidewire lumen 340.
Tube body 310 is preferably shaped to cylinder, to be adapted to the shape of blood vessel, to reduce the loss to blood vessel.Tube body 310 proximal part has proximal end bore 360, and proximal end bore 360 is adapted so that extracorporeal liquid flows into lumen 320 by proximal end bore 360. The distal portions of tube body 310 have remote stomidium 350, and remote stomidium 350 is adapted so that internal blood and extracorporeal liquid pass through remote stomidium 350 outflow lumens 320.Remote stomidium 350 can be connected to a negative pressure device, for the blood flow of embolic occlusion distal end to be drained to body Outside, negative pressure device can be vacuum pump or other devices that can generate negative pressure.
There are multiple side openings 311, the position of multiple side openings 311 can be located at the middle section of tube body, Huo Zhezhong on tube body 310 Between part close to proximal part or middle section close to distal portions, depending on the length of thrombus, internal blood passes through multiple Side opening 311 flows into lumen 320.The number of side opening 311 is multiple, preferably 3-5.The diameter of multiple side openings 311 can be identical, It can also be different, such as aperture is gradually increased from the proximal part distal end portion of tube body 310, or from the proximal end of tube body 310 Part distal end portion is gradually reduced.Multiple side openings 311 can be arranged in a straight line, or be arranged in other arbitrary shapes.
Lumen 320 is the hollow space inside tube body 310, it is preferable that the shape of lumen 320 and the shape one of tube body 310 It causes, such as cylindrical.Lumen 320 is through-hole, has run through entire body portion, and be communicated with the outside.
It adjusts seal wire 330 to be inserted into lumen 320, for closing side opening 311.Adjust being preferably shaped to and managing for seal wire 330 The shape of chamber 320 is consistent, moves in lumen 320 convenient for adjusting seal wire 330.Adjust seal wire 330 diameter preferably and lumen 320 internal diameter is consistent, and to prevent blood perfusion from flowing out from the proximal end of conduit, the efficiency of hemoperfusion can be improved.
Guiding wire chamber 340 is located at the outer wall of tube body 310, and for penetrating guiding wire, the guidance of conduit 300 is extremely included blood The target site of bolt.Guiding wire chamber 340 can extend in entire tube body 310, can also extend in the part of tube body 310.Fig. 4 The cross section of guiding wire chamber 340 and lumen 320 is shown, the length of guiding wire chamber 340 is not limited to a position shown in Fig. 1 In the distal portions of conduit 310.From Fig. 1 as can be seen that the cross section of lumen 320 and guiding wire chamber 340 is all round, and And the caliber of lumen 320 is significantly larger than the caliber of guiding wire chamber 340.
Fig. 5 is schematic diagram of the adjustable perfusion conduit 300 in thrombi of an embodiment according to the present utility model.
As shown in figure 5, conduit 300 enters from the proximal end P (Proximal) of embolic occlusion section, entire thrombus T is passed through (Thrombosis), into the distal end D (Distal) of embolic occlusion section, the proximal end bore 360 of tube body 310 is located at external, tube body 310 Multiple side openings 311 be located in proximal vessel, the remote stomidium 350 of tube body 310 is located at the distal end of embolic occlusion section.
The working principle of adjustable perfusion conduit 300 is described below.
Seal wire 330 will be adjusted to be inserted into the lumen 320 of conduit 300, side opening 311 is all closed, adjusting then will be inserted with The guidance of conduit 300 of seal wire 330 is to target thrombi, and side opening 311 is entirely closed at this time, without blood from embolic occlusion The proximal end of section is perfused to the distal end of embolic occlusion section.Move backward and adjust seal wire 330, side opening 311 starts to open, blood start from The proximal end of embolic occlusion section is perfused to the distal end of embolic occlusion section, moves backward with seal wire 330 is adjusted, the side opening of opening is got over More, the blood of perfusion is more, until restoration of blood flow is perfused to 100%.
By adjusting the movement of seal wire, it can adjust the open number of side opening, and then adjust the open area of side opening, make side opening Open area gradually increases, and the blood perfusion being perfused from the proximal end of embolic occlusion section to the distal end of embolic occlusion section also gradually increases Add, realize it is gradual excessively, avoid blood flow and restore the damage caused by blood vessel suddenly.
Example IV
Fig. 6 is the schematic diagram of the adjustable perfusion conduit 400 of another embodiment according to the present utility model.Adjustable perfusion Conduit 400 includes tube body 410, lumen 420, side opening 411, adjusting seal wire 430 and seal wire guidewire lumen 440, tube body 410, lumen 420, side opening 411, adjust seal wire 430, seal wire guidewire lumen 440 be similar to tube body 310 shown in Fig. 4, lumen 320, side opening 311, Seal wire 330 is adjusted, seal wire guidewire lumen 340, details are not described herein again.
Adjustable perfusion conduit 400 further includes sacculus 470.Sacculus 470 is attached on tube body 410, spherical in shape or oval. Fig. 6 shows sacculus 470 and is located between side opening 411 and the remote stomidium 450 of tube body 410, but not limited to this, sacculus 470 may be alternatively located at The distal end of side opening 411.Sacculus 470 can be inflatable air bag, air bag can be made to expand by injection liquid or gas, liquid Or gas can be entered inside inflatable air bag by pipeline (not shown), pipeline can be located at the outside of tube body 410, The inside of tube body 410 can also be located at, it is preferable that pipeline is located at the inside of tube body 410, to reduce the size of conduit, and then drops The low damage to blood vessel.
When adjustable perfusion conduit 400 enters thrombi, side opening 411 is located at the proximal end of embolic occlusion section, remote stomidium Positioned at the distal end of embolic occlusion section, for sacculus 470 between side opening 411 and remote stomidium, sacculus 470 can be located at embolic occlusion section Proximal end or embolic occlusion section distal end, after injecting gas or liquid by pipeline, sacculus 470 expands, by embolic occlusion section Proximal end and the distal end of embolic occlusion section separate, and can preferably block the flowing of blood, can more precisely control restoration of blood flow It is gradual.
Although the utility model is described with reference to current specific embodiment, ordinary skill in the art Personnel it should be appreciated that more than embodiment be intended merely to illustrate the utility model, be detached from the spirit of the present invention no In the case of can also make various equivalent change or replacement, therefore, as long as to upper in the spirit of the utility model State the variation of embodiment, modification will all be fallen in the range of following claims.

Claims (10)

1. a kind of adjustable perfusion system, the adjustable perfusion system includes conduit and pressure-regulating device, which is characterized in that
Wherein, the conduit includes tube body and lumen;
There are multiple side openings, the multiple side opening is adapted so that internal blood flows into the lumen on the tube body;
The proximal part of the tube body has proximal end bore, and the proximal end bore is adapted so that extracorporeal liquid flows into the lumen;
The distal portions of the tube body have remote stomidium, and the remote stomidium is adapted so that the internal blood and the extracorporeal liquid Flow out the lumen;
The pressure-regulating device is connected to the proximal end bore, for adjusting the pressure of the extracorporeal liquid.
2. adjustable perfusion system according to claim 1, which is characterized in that the pressure-regulating device and the proximal end It is connected between hole by removably.
3. adjustable perfusion system according to claim 2, which is characterized in that the removably includes that screw thread connects It connects.
4. adjustable perfusion system according to claim 1, which is characterized in that the conduit further includes operation guidewire lumen, The operation guidewire lumen is for being inserted into manipulation seal wire to guide the conduit to enter thrombi.
5. adjustable perfusion system according to claim 1, which is characterized in that further include the expanded spheres being attached on tube body Capsule.
6. adjustable perfusion system according to claim 1, which is characterized in that further include being connected to bearing for the remote stomidium Press drainage device, for by the blood drainage of distal portions to external.
7. a kind of adjustable perfusion conduit, the adjustable perfusion conduit includes tube body, lumen and adjusting seal wire;Its feature exists In,
The tube body has multiple side openings, and the multiple side opening is adapted so that internal blood flows into the lumen;
The proximal part of the tube body has proximal end bore, and the adjusting seal wire is suitable for entering the lumen by the proximal end bore, And when the adjusting seal wire is from the distal portions proximally partial movement of the conduit so that the opening number of the side opening by It is cumulative to add;
The distal portions of the tube body have remote stomidium, and the remote stomidium is adapted so that the internal blood flows out the lumen.
8. adjustable perfusion conduit as claimed in claim 7, which is characterized in that the multiple side opening is arranged in a straight line, and each The diameter of the side opening is identical.
9. adjustable perfusion conduit as claimed in claim 7, which is characterized in that the diameter of the multiple side opening is from distal end to close End gradually increases.
10. adjustable perfusion conduit as claimed in claim 7, which is characterized in that further include the expanded spheres being attached on tube body Capsule.
CN201820360740.XU 2018-03-16 2018-03-16 A kind of adjustable perfusion system and perfusion conduit Active CN208927393U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110251808A (en) * 2019-07-25 2019-09-20 汇康(昆山)医疗科技有限公司 A kind of catheter sheath of the sheath tube body with porous structure
CN110668380A (en) * 2019-10-30 2020-01-10 苏州克劳丽化妆品有限公司 Nondestructive filling equipment and method containing solid particle colloid
CN116672032A (en) * 2023-08-03 2023-09-01 清华大学 thrombus aspiration catheter

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110251808A (en) * 2019-07-25 2019-09-20 汇康(昆山)医疗科技有限公司 A kind of catheter sheath of the sheath tube body with porous structure
CN110668380A (en) * 2019-10-30 2020-01-10 苏州克劳丽化妆品有限公司 Nondestructive filling equipment and method containing solid particle colloid
CN110668380B (en) * 2019-10-30 2021-03-30 苏州克劳丽化妆品有限公司 Nondestructive filling equipment and method containing solid particle colloid
CN116672032A (en) * 2023-08-03 2023-09-01 清华大学 thrombus aspiration catheter
CN116672032B (en) * 2023-08-03 2024-01-12 清华大学 Thrombus aspiration catheter

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