CN208910411U - A kind of Portable percutaneous spinal puncture positioning device - Google Patents

A kind of Portable percutaneous spinal puncture positioning device Download PDF

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Publication number
CN208910411U
CN208910411U CN201820495188.5U CN201820495188U CN208910411U CN 208910411 U CN208910411 U CN 208910411U CN 201820495188 U CN201820495188 U CN 201820495188U CN 208910411 U CN208910411 U CN 208910411U
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rotating member
arc groove
positioning
frame body
plate
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CN201820495188.5U
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贾志强
贺西京
李三强
赵利涛
邢建武
吕海文
郭明柯
邢丙文
刘一毅
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Henan University Of Science And Technology Second Affiliated Hospital
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Individual
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Abstract

A kind of Portable percutaneous spinal puncture positioning device, the device include positioning frame body, rotating member and calibration loop, and the one end of positioning frame body offers arc groove, and are equipped with angle index in the circumferential direction of arc groove and the outside wall surface of calibration loop in the outside wall surface of the end;Rotating member has a positioning end and turning end, and rotating member positioning end is overlapped with the center of circle of arc groove, the power unit for driving the rotation of rotating member positioning end is equipped in positioning frame body, rotating member being capable of moving radially along arc groove;One end of calibration loop is connect with rotating member, and plane is vertical with plane where the end of positioning frame body where making calibration loop, and guide pad is connected on calibration loop, and guide pad is equipped with the pilot hole for wearing puncture needle, and the central axis of pilot hole is directed toward the center of circle of arc groove.The utility model provides that a kind of structure is simple, easily disinfection, guide device at low cost, and the device volume is small, prevents take up operating table too large space, and easily disinfection.

Description

A kind of Portable percutaneous spinal puncture positioning device
Technical field
The utility model relates to the field of medical instrument technology, and in particular to a kind of Portable percutaneous spinal puncture positioning dress It sets.
Background technique
As the theory of vertebral column minimally invasive surgery constantly improve, the continuous development of minimal invasive techniques, the subject is already from minimally invasive side To gradually moving towards precision, digitlization, intelligence.Modern vertebral column minimally invasive disciplines of surgery is defined as goalkeeper's number by many scholars Word, intelligence, airmanship, endoscopic technic etc. are melted into the interdisciplinary study of spinal surgery.It is identical as open surgery, minimally invasive spine surgical By using one or more small notch or puncture channel, with special instrument and device, under image instrument monitoring Or the lower completion of airmanship guidance punctures.Compared with traditional technology, have a clear superiority: notch is small, tissue trauma is small, bleeding Less, manipulation accuracy is high, postoperative function restores fast, the period of being hospitalized is short etc..
Currently, the common airmanship that punctures is divided into three kinds, the first is doctor's whole process with rich experiences in perspective In the case of adjustment puncture angle complete;Second is to utilize mainframe computer digital navigation robot device;The third is utilization Backbone positioning device.These devices respectively have shortcoming, the first patient need to be experienced doctor, also, need in art more Secondary Fluoroscopy location adjusts direction, angle and the depth of puncture needle, could obtain satisfied point of puncture and puncture path, and art Person, when adjusting localised puncture direction, can stimulate peripheral nerve and vascular tissue according to feel, it is most important that, repeatedly perspective increases The amount of radiation of patient and patient are added;Second of needs huge sum of money purchases large scale equipment, is difficult to carry out for most hospitals; The third backbone positioning device is to be improved in Clinical feasibility and navigation accuracy and big at present all in the exploratory stage Most equipment are larger, are not easy to sterilize, and need to convert obtaining puncture angle and depth indirectly according to measured value formula, because of patient It is mobile and when causing to change puncture position, need to readjust parameter, relative increase operating time, amount of bleeding and infection risk Deng.
Utility model content
The purpose of the utility model is to provide a kind of Portable percutaneous spinal puncture positioning devices, and the apparatus structure is simple, It is small in size, easily sterilize.
A kind of the utility model technical solution used for the above purpose are as follows: Portable percutaneous spinal puncture positioning Device, the device include positioning frame body, rotating member and calibration loop, and the one end of positioning frame body offers arc groove, and posting Angle index is circumferentially with along arc groove in the outside wall surface of the body end;Rotating member has a positioning end and turning end, In, the positioning end of rotating member is overlapped setting with the center of circle of arc groove, is equipped with the positioning end for being able to drive rotating member in positioning frame body The turning end of the power unit of rotation, rotating member is limited in arc groove, enables rotating member moving radially along arc groove; It is circumferentially with angle index along it in the outside wall surface of calibration loop, and one end of calibration loop is connect with rotating member, makes calibration loop place Plane be equipped with arc groove positioning frame body end where plane be mutually perpendicular to, be slidably connected with and lead on calibration loop To block, guide pad is equipped with the pilot hole for wearing puncture needle, and the central axis of pilot hole is directed toward the center of circle of arc groove always.
Wherein, the power unit includes the sector gear and complete gear of external toothing setting, sector teeth number Greater than the number of teeth of complete gear, the center of rotation of sector gear is fixedly connected by rotation axis with the positioning end of rotating member, completely The center of rotation of gear is connected with handle, and one end of handle is mounted on the inner wall of positioning frame body by bearing.
Wherein, the turning end of rotating member is connected with limited post, limited post protrude into arc groove and with arc groove clearance fit, The nut and gasket for preventing limited post from deviating from from arc groove are arranged on the limited post inside positioning frame body.
In the utility model, the calibration loop includes two arc plates disposed in parallel, and the guide pad is by two The U-shaped structure of a movable plate disposed in parallel and the connecting plate composition for connecting two movable plates, two movable plates slidings It is cooperatively connected on two arc plates, one end of two arc plates is fixedly connected with rotating member, and the other end of two arc plates is logical It crosses and is fixedly connected equipped with the limit plate for preventing guide pad from deviating from from calibration loop.
Further, the pilot hole is provided on connecting plate;The rotating member is straight-bar structure, and rotating member Positioning end is arcuate structure, and the extreme lower position of arcuate structure is overlapped setting with the center of circle of arc groove.
Wherein, the center of circle of arc groove is located on arris of the positioning frame body equipped with the end of arc groove.
In the utility model, the positioning frame body includes an inside casing and two outline borders being set in outside inside casing, Inside casing is by bottom plate and is vertically connected on two interior plates of bottom plate opposite sides and forms, two outline borders be by two outer panels with And the framework of the U-shaped structure of the sealing plate composition of two outer panels of connection, two outline borders are interior by respective outer panel and inside casing Side plate sliding connection;The rotating member and calibration loop is connected on the sealing plate of one of outline border.
Further, the outer bottom face of bottom plate of bottom face and inside casing of the outer panel of two outline borders is concordant, and on bottom plate Offer the guide groove of several and the perpendicular setting of interior plate.
Further, several location holes, and the location hole being located on the same interior plate are equipped on each interior plate Uniform intervals are arranged, and locating slot, outer panel and interior plate are equipped on the outer panel of each outline border by passing through locating slot and determining The bolt in position hole is connected.
Preferably, the lower part of the outside wall surface of two interior plates and four outer panels is equipped with length scale line.
The utility model has the advantages that the utility model provide a kind of design rationally, structure is simple, easily disinfection, at low cost, easily universal Guide device, the device is easy to operate, shortens patient's learning curve, and positioning time is shorter, reduces patient and patient Amount of radiation.The device volume is small, prevents take up operating table too large space, and easily disinfection.
Detailed description of the invention
Fig. 1 and Fig. 2 is the structural schematic diagram of the utility model;
Fig. 3 is the schematic diagram of calibration loop and rotating member in Fig. 1;
Fig. 4 is Fig. 2 main view;
Fig. 5 is the schematic diagram of one of outline border in Fig. 2;
Fig. 6 is the topology view in the other directions Fig. 5;
Fig. 7 is the right view of Fig. 5;
Fig. 8 is the left view of Fig. 5;
Fig. 9 is the label result figure on shaft-like bit image;
Figure 10 is the label result figure on sagittal bitmap images.
Appended drawing reference: 1, positioning frame body;2, inside casing, 200, bottom plate, 201, interior plate, 202, location hole, 203, guide groove, 204, strip groove;3, outline border, 300, outer panel, 301, sealing plate, 302, locating slot, 303, bolt;4, rotating member, 400, limit Column, 401 nuts, 402, gasket, 403, positioning end, 404, turning end;5, calibration loop, 500, arc plate, 501, limit plate;6, circle Arc slot, 7, guide pad, 700, movable plate, 701, connecting plate, 8, pilot hole, 9, sector gear, 10, complete gear, 11, rotation Axis, 12, handle, 13, screw.
Specific embodiment
The technical solution of the utility model is clearly and completely described below in conjunction with attached drawing, it is clear that described Embodiment is the utility model a part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, originally Field those of ordinary skill every other embodiment obtained without making creative work belongs to practical Novel protected range.
A kind of Portable percutaneous spinal puncture positioning device, as shown in figure 4, the device includes positioning frame body 1, rotating member 4 With calibration loop 5, as depicted in figs. 1 and 2, the one end of positioning frame body 1 offers arc groove 6, and 1 end of positioning frame body is outer Angle index is circumferentially with along arc groove 6 on wall surface.
Wherein, positioning frame body 1 includes an inside casing 2 and two outline borders 3 being set in outside inside casing 2, and inside casing 2 is by bottom plate 200 form with two interior plates 201 for being vertically connected on 200 opposite sides of bottom plate, and each outline border 3 is for by two outer panels 300 and the framework of the U-shaped structure that the sealing plates 301 of two outer panels 300 forms is connected, two outline borders 3 pass through respective outside The interior plate 201 of plate 300 and inside casing 2 is slidably connected, and specific implementation form can be with are as follows: in the outside wall surface of two interior plates Equipped with sliding rail, it is equipped on the inner wall of four outer panels of two outline borders and cooperates the sliding slot being slidably connected with sliding rail;The sliding Mating connection can also use other conventionally known sliding connection structures.Positioning frame body 1 includes an inside casing 2 and is set in Drawable two outline borders 3 outside inside casing 2, since human body back unilateral side has small radian, it is however generally that, the left and right sides is pair Claim, after device pumping is opened, where being contacted with the human body back left and right sides in plane and nuclear magnetic resonance image check image Face where skin matches.
The bottom face of the outer panel 300 of two outline borders 3 and the outer bottom face of bottom plate 200 of inside casing 2 are concordant, and bottom plate 200 On offer the guide grooves 203 of several and the perpendicular setting of interior plate 201.Guide groove 203 positions spine when can be as positioning Prominent reference line guarantees face E where the skin in guide groove 203 and Figure 10 on sagittal bitmap images2Vertical line be overlapped. Wherein, strip groove 204 is also provided on bottom plate 200, strip groove 204 is mutually perpendicular to guide groove 203, and strip groove 204 is prolonged Stretching line can be by the center of circle of the arc groove 6 on sealing plate 301.
Several location holes 202, and the location hole being located on the same interior plate 201 are equipped on each interior plate 201 The setting of 202 uniform intervals, the center of each location hole 202 is located along the same line;It is equipped on the outer panel 300 of each outline border 3 Locating slot 302, outer panel 300 are connected with interior plate 201 by passing through the bolt 303 of locating slot 302 and location hole 202.Its In, the center line of locating slot 302 and the straight line by the center of each location hole 202 coincide setting.
Preferably, the lower part of the outside wall surface of two interior plates, 201, four outer panels 300 is equipped with length scale line, is convenient for When using the device, length is measured using the length scale line of positioning frame body, without in addition purchasing other devices.
Wherein, rotating member 4 and calibration loop 5 are connected on the sealing plate 301 of one of outline border 3.Preferably, the top of inside casing Equipped with dismountable transparency cover (not shown), it is conducive to safe operation.
As shown in Figure 1, Figure 2 and Figure 3, rotating member 4 has a positioning end 403 and turning end 404, wherein rotating member 4 Positioning end 403 is overlapped setting with the center of circle of arc groove 6, and the positioning end rotation for being able to drive rotating member 4 is equipped in positioning frame body 1 The turning end 404 of power unit, rotating member 4 is limited in arc groove 6, and rotating member 4 is enable to move along the radial direction of arc groove 6 It is dynamic.
Specific implementation form are as follows: as shown in Figure 5 and Figure 6, the turning end 404 of rotating member 4 is connected with limited post 400, limit Column 400 protrude into arc groove 6 and with 6 clearance fit of arc groove, be arranged on the limited post 400 inside positioning frame body 1 anti- Only nut 401 and gasket 402 that limited post 400 is deviate from from arc groove 6.
Wherein, it is circumferentially with angle index along it in the outside wall surface of calibration loop 5, and one end of calibration loop 5 and rotating member 4 connect It connects, the plane where making calibration loop 5 is mutually perpendicular to the plane where the end for the positioning frame body 1 for being equipped with arc groove 6, such as Fig. 3 It is shown, guide pad 7 is slidably connected on calibration loop 5, guide pad 7 is equipped with the pilot hole 8 for wearing puncture needle, guiding The central axis in hole 8 is directed toward the center of circle of arc groove 6 always.Wherein, guide pad 7 is equipped with mounting hole, as shown in figure 5, the mounting hole Screw 13 is inside installed, by tightening screw 13, makes the end abutment of screw 13 on calibration loop 5, realizes that the positioning of guide pad 7 is solid It is scheduled on calibration loop 5.
As shown in figure 3, calibration loop 5 includes two arc plates 500 disposed in parallel, the guide pad 7 is flat by two The U-shaped structure that the movable plate 700 of row setting and the connecting plate 701 for connecting two movable plates 700 are constituted, two movable plates 700 sliding connections are on two arc plates 500, and one end of two arc plates 500 is fixedly connected with rotating member 4, two circles The other end of arc plate 500 is fixedly connected by limit plate 501, and limit plate 501 prevents guide pad 7 from deviating from from calibration loop 5.Lead Mounting hole on block 7 is located on movable plate 700, and screw 13 is threaded through on movable plate 700;Pilot hole 8 is provided with connecting plate 701 On.
Preferably, rotating member 4 is straight-bar structure, and the positioning end 403 of rotating member 4 is arcuate structure, and arcuate structure is most Lower position is overlapped setting with the center of circle of arc groove 6.
Preferably, as shown in fig. 7, the center of circle of arc groove 6 is located at the arris of end of the positioning frame body 1 equipped with arc groove 6 On, i.e., the center of circle of arc groove 6 is located on the arris of sealing plate 301.It, should be in the base for guaranteeing using effect in the actual fabrication device On plinth, keep the diameter of rotation axis 11 small as far as possible, is defaulted as the center of rotation axis i.e. on the arris of the lower part of sealing plate.
In the utility model, as shown in Fig. 5, Fig. 6 and Fig. 9, power unit includes the sector gear 9 and complete of external toothing setting All gear 10, the number of teeth of sector gear 9 are greater than the number of teeth of complete gear 10, and the center of rotation of sector gear 9 passes through rotation axis 11 It is fixedly connected with the positioning end of rotating member 4, the center of rotation of complete gear 10 is connected with handle 12, and one end of handle 12 passes through axis On the inner wall for holding the sealing plate 301 for being mounted on positioning frame body 1.Preferably, it is equipped on the flank of tooth of sector gear and complete gear Several lightening hole (not shown)s, can reduce the weight of gear, convenient for operation.
The utility model is using image as object, by positioning on the image, and then obtains objective, accurate position location, For non-treatment purpose.
The device is widely used, can be used for puncturing the localised puncture of interverbebral disc and the radio frequency of interverbebral disc, it may also be used for ridge The implantation positioning of column pedicle nail;By the measurement of image, it is accurately positioned navigation, increases puncture accuracy.
Localization method, that is, the application method of the utility model, comprising the following steps:
Step 1: the image is as shown in figure 9, find out on x-ray, CT or nuclear magnetic resonance image scholar's body shaft-like bit image Corresponding target area site location, i.e., target area position to be treated;Then in nuclear magnetic resonance image check image, sieve Select the shaft-like position layer images and corresponding sagittal image at target area position;
Step 2: find out the spinous points at target area position on the shaft-like position layer images screened, and screening Puncture path is drawn on the layer images of shaft-like position, is labeled as r, face E where the skin on the puncture path and shaft-like bit image1's Joint is labeled as O1;By O1Face E where making the skin on shaft-like bit image1Vertical line, be labeled as H1;H1With shaft-like position The angle punctured between inserting needle direction on image, is labeled as β1;Make the place of the skin on shaft-like bit image by the spinous points Face E1Vertical line, be labeled as H2;H1With H2The distance between, it is labeled as D1;Mark result as shown in Figure 9;
Step 3: finding out its corresponding nuclear magnetic resonance image scholar body sagittal bitmap according to the shaft-like bit image of step 2 Image, the image is as shown in Figure 10, in Figure 10, is illustrated by taking two lumbar vertebras of L4, L5 as an example, thoracic vertebrae, cervical vertebra reference Lumbar vertebra.
The level line for making above-mentioned shaft-like bit image is found out on sagittal bitmap images, is labeled as a;And in sagittal plain The spinous process of two centrums in target area is found out on figure image, and makes two spinous process in face E where the skin on sagittal bitmap images2 Projection, be respectively labeled as G1、G2, G is drawn on sagittal bitmap images1And G2Connecting line, be labeled as b;The friendship of line b and line a Crunode is labeled as O2;O2With G2The distance between be labeled as D2;By O2Make the vertical line of line b, c is labeled as, between line c and line a Angle, be labeled as β2;The results are shown in Figure 10 for label;
Step 4: the angle beta determined according to step 21, the position of guide pad on calibration loop is adjusted, the center of pilot hole is made Angle between axis and the center of circle of arc groove is β1
Step 5: the angle beta determined according to step 32, the position of the rotating member of positioning frame body end is adjusted, rotating member is made Angle between the center of circle of arc groove is β2.Wherein, using the complete gear and sector gear being engaged, calibration loop is realized The fine tuning of rotational angle on posting end.
Wherein, spinous points described in step 2 refer to nearest position of the level spinous process apart from face where skin;It is general and Speech, the vertical line in face where making the skin on shaft-like bit image by the spinous points are the central axes of the centrum.In step 3 Spinous process be conventional meaning on centrum spinous process, that is, refer to the thorn-like in vertebra neural arch center or the back bump of scute shape.
When making x-ray, CT or nuclear magnetic resonance image scholar's body shaft-like bit image, patient need to be made to take prone position, utilize C arm The upper centrum spinous process of illness level and the next centrum spinous process are oriented, bow pen marks spinous process line and its vertical center line, and Wire is placed in two lines, utilize C arm position observation again and adjusts wire, has an X-rayed spinous process perspective point in wire On line, with bow pen again marking relevant position.
When in use, using the spinous process of neighbouring centrum as standard, the variation of position of human body by a small margin will not influence the device To the variation of neighbouring spinous process position, and then the position location of the device of the utility model is not influenced, make accurate positioning.Meanwhile it is fixed Position framework is equipped with length scale, positioning frame body can be made to use as scale.The utility model utilizes the complete gear being engaged And sector gear, it can be realized the fine tuning of rotational angle of the calibration loop on sealing plate, keep position location more accurate.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " is pacified Dress ", " connected ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integrally Connection;It can be directly connected, the connection inside two elements can also be can be indirectly connected through an intermediary.For For those skilled in the art, the concrete meaning of above-mentioned term in the present invention can be understood with regard to concrete condition.
The person that is not specified actual conditions in embodiment, carries out according to normal conditions.
Above embodiments are in order to illustrate the technical solution of the utility model, and its purpose is makes those skilled in the art The content of the utility model can be understood and be practiced, but do not limited the protection scope of the present invention.It is all according to The equivalent changes or modifications made according to the substantive content of the utility model, should all cover in the protection scope of the utility model It is interior.

Claims (10)

1. a kind of Portable percutaneous spinal puncture positioning device, it is characterised in that: the device includes positioning frame body, rotating member and quarter Ring is spent, the one end of positioning frame body offers arc groove, and the circumferential direction in the outside wall surface of the positioning frame body end along arc groove is set Angled scale;Rotating member has a positioning end and turning end, wherein the positioning end of rotating member is overlapped with the center of circle of arc groove Setting, positioning frame body is interior to be equipped with the power unit for being able to drive the positioning end rotation of rotating member, and the turning end of rotating member is limited In arc groove, enable rotating member moving radially along arc groove;Angle is circumferentially with along it in the outside wall surface of calibration loop to carve Degree, and one end of calibration loop is connect with rotating member, makes the end of the plane and the positioning frame body for being equipped with arc groove where calibration loop The plane at place is mutually perpendicular to, and guide pad is slidably connected on calibration loop, and guide pad is equipped with for wearing puncture needle Pilot hole, the central axis of pilot hole are directed toward the center of circle of arc groove always.
2. a kind of Portable percutaneous spinal puncture positioning device as described in claim 1, it is characterised in that: the power list Member includes the sector gear and complete gear of external toothing setting, and sector teeth number is greater than the number of teeth of complete gear, sector The center of rotation of wheel is fixedly connected by rotation axis with the positioning end of rotating member, and the center of rotation of complete gear is connected with handle, One end of handle is mounted on the inner wall of positioning frame body by bearing.
3. a kind of Portable percutaneous spinal puncture positioning device as described in claim 1, it is characterised in that: the rotation of rotating member End is connected with limited post, and limited post protrudes into arc groove and with arc groove clearance fit, limited post inside positioning frame body On be arranged with the nut and gasket for preventing limited post from deviating from from arc groove.
4. a kind of Portable percutaneous spinal puncture positioning device as described in claim 1, it is characterised in that: the calibration loop Including two arc plates disposed in parallel, the guide pad is by two movable plates disposed in parallel and for connecting two The U-shaped structure that the connecting plate of movable plate is constituted, two movable plates sliding connections on two arc plates, two arc plates One end is fixedly connected with rotating member, and the other end of two arc plates passes through the limit for being equipped with and preventing guide pad from deviating from from calibration loop Plate is fixedly connected.
5. a kind of Portable percutaneous spinal puncture positioning device as claimed in claim 4, it is characterised in that: the pilot hole It is provided on connecting plate;The rotating member is straight-bar structure, and the positioning end of rotating member is arcuate structure, and arcuate structure is most Lower position is overlapped setting with the center of circle of arc groove.
6. a kind of Portable percutaneous spinal puncture positioning device as claimed in claim 1 or 5, it is characterised in that: arc groove The center of circle is located on arris of the positioning frame body equipped with the end of arc groove.
7. a kind of Portable percutaneous spinal puncture positioning device as described in claim 1, it is characterised in that: the posting Body includes an inside casing and two outline borders being set in outside inside casing, and inside casing is by bottom plate and is vertically connected on bottom plate opposite sides Two interior plates composition, two outline borders are by two outer panels and to connect the U-shaped knots that form of sealing plate of two outer panels The framework of structure, two outline borders are slidably connected by the interior plate of respective outer panel and inside casing;The rotating member and quarter Degree ring is connected on the sealing plate of one of outline border.
8. a kind of Portable percutaneous spinal puncture positioning device as claimed in claim 7, it is characterised in that: two outline borders it is outer The outer bottom face of bottom plate of bottom face and inside casing of side plate is concordant, and several and the perpendicular setting of interior plate are offered on bottom plate Guide groove.
9. a kind of Portable percutaneous spinal puncture positioning device as claimed in claim 7, it is characterised in that: on each interior plate The location hole uniform intervals setting for being equipped with several location holes, and being located on the same interior plate, the outer panel of each outline border On be equipped with locating slot, outer panel is connected with interior plate by passing through the bolt of locating slot and location hole.
10. a kind of Portable percutaneous spinal puncture positioning device as claimed in claim 7, it is characterised in that: two interior plates Length scale line is equipped with the lower part of the outside wall surface of four outer panels.
CN201820495188.5U 2018-04-09 2018-04-09 A kind of Portable percutaneous spinal puncture positioning device Active CN208910411U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201820495188.5U CN208910411U (en) 2018-04-09 2018-04-09 A kind of Portable percutaneous spinal puncture positioning device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201820495188.5U CN208910411U (en) 2018-04-09 2018-04-09 A kind of Portable percutaneous spinal puncture positioning device

Publications (1)

Publication Number Publication Date
CN208910411U true CN208910411U (en) 2019-05-31

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CN201820495188.5U Active CN208910411U (en) 2018-04-09 2018-04-09 A kind of Portable percutaneous spinal puncture positioning device

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Effective date of registration: 20210726

Address after: 471000 No.80 Jinguyuan Road, Xigong District, Luoyang City, Henan Province

Patentee after: HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY SECOND AFFILIATED Hospital

Address before: 471000 No.80 Jinguyuan Road, Xigong District, Luoyang City, Henan Province

Patentee before: Jia Zhiqiang