CN208905664U - Plugging device - Google Patents
Plugging device Download PDFInfo
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- CN208905664U CN208905664U CN201820918827.4U CN201820918827U CN208905664U CN 208905664 U CN208905664 U CN 208905664U CN 201820918827 U CN201820918827 U CN 201820918827U CN 208905664 U CN208905664 U CN 208905664U
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- sleeve
- flange
- plugging device
- network management
- auxiliary section
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Abstract
The utility model provides a kind of plugging device, network management, first sleeve and the second sleeve surrounded including multi-filament material, tapped through hole is provided in the middle part of first sleeve, first sleeve have auxiliary section and with integrally formed first flange in auxiliary section, it is in circular hole that first end opening of network management, which is shunk, circular hole is socketed on auxiliary section, first flange with a thickness of 0.1 millimeter to 1 millimeter, second sleeve is sleeved on auxiliary section, one end of second sleeve towards the first flange is provided with the second flange, and the first end of network management is pressed between the first flange and the second flange.The plugging device, which has the advantages that reduce to generate thrombotic risk, reduce the probability of cardiovascular organization generation damage and inflammation and reduce endothelial cell, climbs clad can.
Description
Technical field
The utility model relates to the field of medical instrument technology, specifically, being to be related to a kind of plugging device.
Background technique
Cardiac catheterization is a kind of minimally invasive treatment method, is increasingly adopted by doctor, is received by patient,
It can be used for for the medical instruments such as plugging device, bracket, filter being implanted into the angiocarpy of human body through intubation intervention method.
Plugging device is a kind of medical equipment for treating heart defect, mainly by through intubation intervention method by plugging device
The defect for being placed into heart blocks defect, cures cardiopathic purpose completely to reach.And general envelope
Stifled device is to carry out controllable type release to it using threaded connection, for example, when the size of plugging device in therapeutic process is improper or puts
Plugging device at that time, can not be recycled in conduit, and pull out via conduit and replaced in vitro by seated position again, and when closure
When the size of device is suitable or prevents suo loco, plugging device can be made to be separated with wirerope by rotation wirerope.But it is existing
The plugging device overwhelming majority have the drawback that: the end of plugging device or the threaded nut at both ends are to protrude from plugging device
Closure disk outside.
As shown in Figure 1, the closure disk 110 of existing plugging device 100 is usually by more fine wires or macromolecule silk etc.
The network management that silk material 111 is woven into is made, and the end of network management is provided with the sleeve for collecting multi-filament material simultaneously
120, the interconnecting piece 131 of nut 130 is sleeved on outside sleeve 120, finally sleeve 120 and interconnecting piece 131 are welded and fixed.
As shown in Fig. 2, in order to guarantee that wirerope 200 and plugging device 100 are able to carry out firm connection, so that the end of wirerope 200 is necessary
Bolt 210 with sufficient length is screwed with the nut 130 of plugging device 100, with guarantee the connection of auxiliary section reliability and
Safety.However, as shown in figure 3, due to manufacturing procedure, so that being processed in the bolt 210 to 200 end of wirerope
When, the end of bolt 210 can at least have the tail portion 220 of the imperfect thread with 0.5 millimeter to 1 millimeter, lead to tail portion 220
On imperfect thread can not sufficiently be screwed with nut 130, weaken the bonding strength of auxiliary section.
Further, since blocking of the end of wirerope 200 by the boundling weld part 112 for blocking disk 110, leads to tail portion 220
It cannot reach outside nut 130, and there is the segment space for occupying nut 130 in tail portion 220, so that the connection for reducing auxiliary section is strong
Degree results in the need for the length by increasing nut 130 to guarantee the connection length of auxiliary section.But above-mentioned way will lead to spiral shell
Mother 130 has major part and can protrude from except the disk for blocking disk 110, and common prominent length is 1 millimeter to 5 millimeters,
And have the drawback that in this way: after plugging device 100 is implanted to target position in angiocarpy, the part outstanding of nut 130 will increase production
The risk of green blood bolt, also, climbed and covered relatively slowly due to the surface endothelial cell of 130 protrusion of nut, and metal parts is sudden and violent for a long time
It is exposed in tissue or blood, the risk for the harmful metal ion for causing metal parts to be discharged into blood increases.
Furthermore influence the unfavorable factor of the safety of existing plugging device 100 further include: the protrusion of nut 130 is also deposited
The risk for influencing the original blood flow mode of human body is being increased, while can also generate friction with the cardiovascular organization of surrounding, in turn
Cardiovascular organization is caused to occur damaging and inflammation.On the other hand, after being implanted into plugging device 100, when patient needs to carry out other Jie
When entering to perform the operation, the transportation system used can generally pass through near the plugging device 100 being implanted into, and lead to 130 protrusion of nut
It may hinder or be hanging to other instruments and influence the operation performed the operation.In addition, generalling use the network management that multi-filament material is woven into
The bracket and filter being made generally can also be provided with sleeve and nut etc., cause to equally exist the risks such as thrombus source.
Exception, sleeve 120 and silk material 111, nut 130 and sleeve 120 are generally by laser welding or argon arc welding
It is fixedly connected, still, since the size of plugging device 100 is smaller, the welding energy being applied in silk material 111 is caused to be difficult to control
It the problem of system, the silk material 111 being commonly present in fixing end is blown and the silk material 111 blown can not be detected, seriously affects
The quality of plugging device 100, and argon arc welding causes to cause operator biggish body harm there is also big problem is radiated.
Summary of the invention
To solve the above-mentioned problems, the main purpose of the utility model is to provide a kind of reduction and generates thrombotic risk, reduces
Cardiovascular organization occurs to damage and the probability of inflammation, reduction endothelial cell climb clad can and not to other devices of subsequent intervention operation
Tool uses the plugging device impacted.
In order to realize the main purpose of the utility model, the utility model provides a kind of plugging device, including multi-filament material encloses
At network management, wherein plugging device further includes first sleeve and second sleeve, and tapped through hole is provided in the middle part of first sleeve,
One sleeve have auxiliary section and with integrally formed first flange in auxiliary section, it is in circular hole, circular hole that the first end opening of network management, which is shunk,
Be socketed on auxiliary section, the first flange with a thickness of 0.1 millimeter to 1 millimeter, second sleeve is sleeved on auxiliary section, the of network management
One end is pressed between the first flange and second sleeve.
Therefore the first flange and second sleeve of first sleeve setting can be to first of the network management in circular hole setting
End is fixed, i.e., is fixed to silk material boundling, and then avoid the occurrence of and needed in the prior art through welding
Problem is fixed to silk material boundling in mode.In addition, the side that silk material boundling is fixed by the first flange and the second flange
Formula can effectively save silk material and occupy the space of first sleeve, and then the network management of the prominent plugging device of first sleeve is greatly lowered
Length, reduce the risk that thrombus generates and effectively reduce endothelial cell and climb clad can.And it is logical that screw thread is arranged in the middle part of first sleeve
Hole enables to the bolt on the wirerope connecting with plugging device that can be pierced by tapped through hole, has both guaranteed the bolt and first set of wirerope
There can be enough screwing lengths between cylinder, and the length of the network management of the prominent plugging device of first sleeve can be effectively reduced, keep away
Exempt from the type of flow of the influence original blood of human body, additionally it is possible to reduce the probability that damage and inflammation occur for cardiovascular organization.
Further embodiment is that one end of second sleeve towards the first flange is provided with the second flange, the first end of network management
It is pressed between the first flange and the second flange.
Therefore second flange can be improved the reliability that the first end of network management is pressed.
Further scheme is that plugging device further includes gasket, and gasket is sleeved on auxiliary section, and gasket is located at circular hole and the
Between two flanges, and gasket is pressed together in the first end of network management.
Therefore gasket can play the role of stop to network management, avoid network management the first flange and the second flange it
Between skid rotation, guarantee network management installation reliability.
Further scheme is that the first screw thread is provided on the peripheral wall of auxiliary section, and the is provided in the middle part of second sleeve
Two screw threads, the first screw thread and the second threaded engagement.
Therefore be threadedly coupled with certain locking function, and first sleeve and second sleeve pass through helicitic texture
It is attached, can be improved the reliability connected between first sleeve and second sleeve, and can guarantee the first flange and second
Flange can the first end to network management effectively compressed.
Further scheme is that the screwing length between the first screw thread and the second screw thread is 0.5 millimeter to 3 millimeters.
Therefore due to plugging device small volume, carried out by the screwing length between the first screw thread and the second screw thread
Setting, can either guarantee the reliability of the connection of first sleeve and second sleeve, and can be avoided first sleeve and/or second set
Cylinder excessively protrudes from except network management since length is too long.
Further scheme is, tapped through hole can screwing length be 1 millimeter to 3 millimeters, and tapped through hole revolves
Close the depth that length is equal to tapped through hole.
Therefore due to the small volume of plugging device, by tapped through hole can screwing length be configured, can
Enough guarantee the reliability that connect with the bolt on wirerope of plugging device, but can be avoided first sleeve due to length is too long and excessively
It protrudes from except network management.
Further scheme is that the first flange, the second flange are annularly arranged, and the diameter of the first flange is greater than second
The diameter of flange.
Therefore second flange be mainly used for for the silk material of network management being pressed together on the first flange, and by the first flange
The diameter that diameter is set greater than the second flange can guarantee that the silk material pressed is supported space with enough, and can guarantee
First flange itself can have enough bearing capacitys.
Further scheme is, auxiliary section and second sleeve are provided with welding structure in one end far from the first flange.
Therefore welding structure further can carry out stop to first sleeve and second sleeve, prevent first sleeve
It is loosened due to occurring with respect to sliding between second sleeve, and welding structure is arranged far to one end of the first flange,
Can be avoided in welding process causes silk material to blow, and guarantees the quality of plugging device.
Further scheme is, the second flange with a thickness of 0.1 millimeter to 1 millimeter.
Therefore the thickness of the second flange is configured, so that can either guarantee the intensity of the second flange, and can
Guarantee the reliability that the first end of network management can be pressed together on the second flange by the second flange.
Further scheme is that the diameter of the first flange is greater than the diameter of the second flange.
Further scheme is that network management is internally provided with polyester dacron or polytetrafluoroethylene (PTFE).
Therefore first flange diameter be set greater than the second flange diameter can guarantee the silk material pressed have
Have it is enough be supported space, and can guarantee that the first flange itself can have enough bearing capacitys again.
Detailed description of the invention
Fig. 1 is the half-section diagram of the plugging device of the prior art.
Fig. 2 is the partial view of the wirerope of the prior art.
Fig. 3 is the attachment structure schematic diagram of prior art plugging device and wirerope.
Fig. 4 is the first state structural schematic diagram of the network management of the utility model plugging device embodiment.
Fig. 5 is the second status architecture schematic diagram of the network management of the utility model plugging device embodiment.
Fig. 6 is the cross-sectional view after the clipped component of the utility model plugging device embodiment.
Fig. 7 is the connection schematic cross-sectional view of the utility model plugging device embodiment.
The following is a further explanation of the present invention with reference to the accompanying drawings and embodiments.
Specific embodiment
Plugging device embodiment:
Referring to Fig. 4 to Fig. 7, plugging device 30 includes network management 31, first sleeve 32, second sleeve 33 and gasket 34.Wherein, net
Pipe 31 surrounds tubular structure by multi-filament material 311, and macromolecule silk material or metal wire material can be used in silk material 311, it is preferable that silk material
311 can be used Nitinol.In addition, the network management 31 being woven into when not carrying out heat-treating profiled, by silk material 311 or meets system
The wire rod being required passes through multiple grids of the first end of network management 31, and then tightens to the opening of the first end of network management 31,
And the opening of the first end of network management 31 is shunk and sees Fig. 5 in circular hole 310().
The middle part of first sleeve 32 has tapped through hole 321, and tapped through hole 321 with bolt 41 on wirerope 4 for being connected
Connect, with realize institute controllable release is carried out to plugging device 30, when by plugging device 30 by wirerope 4 be transferred at heart when, if seal
When the size of stifled device 30 is suitable and placement location is proper, plugging device 30 can be made to be separated with wirerope 4 by rotation wirerope 4,
And then the defect for making plugging device 30 be placed on heart blocks defect;And if plugging device 30 is off size
Plugging device 30 at that time, can be recycled in conduit, and pull out via conduit by suitable and/or placement location again by wirerope 4
It is replaced in vitro.
Compared to the connection type of traditional plugging device and wirerope, connected using the bolt 41 of tapped through hole 321 and wirerope 4
It connects, the bolt 41 on wirerope 4 that can be connect with plugging device 30 can be pierced by tapped through hole 321, and then both guarantee the spiral shell of wirerope 4
There can be enough screwing lengths between bolt 41 and first sleeve 32, and the prominent plugging device of first sleeve 32 can be effectively reduced
The length of 30 network management 31, and then avoid influencing the type of flow of the original blood of human body, additionally it is possible to reduce cardiovascular organization
The probability of damage and inflammation.
First sleeve 32 has auxiliary section 322 and the first flange 323, and auxiliary section 322 and the first flange 323 are integrally formed,
Network management 31 is socketed in the auxiliary section 322 of first sleeve 32 by circular hole 310, it is preferable that the thickness H of the first flange 323 is 0.1 milli
Rice is to 1 millimeter, so that the first flange 323 can either guarantee there is enough intensity, and can guarantee the prominent net of first sleeve 32
The length of pipe 31 is much smaller than the protrusion length of the nut of traditional plugging device, and then can effectively reduce endothelial cell and climb clad can,
The risk for generating thrombus is greatly lowered.
The middle part of second sleeve 33 is provided with through-hole 331, and second sleeve 33 is sleeved on first sleeve 32 by through-hole 331
On auxiliary section 322, and one end of second sleeve 33 towards the first flange 323 is provided with the second flange 332, when 33 sets of second sleeve
After on auxiliary section 332, the first end of network management 31 is pressed between the first flange 323 and the second flange 332, and then to net
The first end of pipe 31 is fixed, with replace it is existing need by welding to the boundling of the silk material 311 of network management 31 into
The fixed problem of row, can effectively reduce the volume of first sleeve 32, and avoid the need for prominent by increasing first sleeve 32
The problem of boundling of silk material 311 of the space of network management 31 to accommodate network management 31.Preferably, the thickness h of the second flange 332 is 0.1
Millimeter so that can either guarantee the intensity of the second flange 332, and can guarantee that the second flange 332 can be by network management 31 to 1 millimeter
First end be pressed together on the reliability on the second flange 323.
Wherein, second sleeve 33 can be sleeved on by way of interference fit on the auxiliary section 322 of first sleeve 32 with
Realize the purpose for being fixedly connected, the first end of network management 31 being fixed of first sleeve 32 and second sleeve 33.And preferably,
It is provided with the first screw thread on the peripheral wall of the auxiliary section 322 of first sleeve 32, is set on the peripheral wall of the through-hole 331 at 33 middle part of second sleeve
It is equipped with the second screw thread, first sleeve 32 is screwed by the second screw thread of the first screw thread and the through-hole of second sleeve 33 331, into
And it realizes to the fixation of first sleeve 32, second sleeve 33 and the purpose that the first end of network management 31 is fixed.Further
Ground, the screwing length between the first screw thread and the second screw thread is 0.5 millimeter to 3 millimeters, because of the small volume of plugging device 30, is led to
It crosses and the screwing length between the first screw thread and the second screw thread is configured, can either guarantee first sleeve 32 and second sleeve 33
Between connection reliability, and can avoid first sleeve 32 and/or second sleeve 33 due to length is too long and excessively
Except prominent and network management 31, so that first sleeve 32 protrudes from the part outside network management 31 and only needs to retain the first flange 323, into
And the risk for generating thrombus is greatly reduced and effectively reduces endothelial cell and climbs clad can.
In addition, the auxiliary section 321 of first sleeve 32 is provided with second sleeve 33 in the first end far from the first flange 323
Welding structure is welded and fixed first sleeve 32 and second sleeve 33 in the first end far from the first flange 323.Welding
Structure can carry out further stop to first sleeve 32 and second sleeve 33, prevent first sleeve 32 and second sleeve 33 it
Between can also effectively avoid welding due to unclamping with respect to interaction, and by the first end that welding structure is arranged far from the first flange 321
It causes the silk material 311 of network management 31 to blow in termination process, guarantees the quality of plugging device 30.
Preferably, between the tapped through hole 321 of first sleeve 32 and the spiral 41 of wirerope 4 can screwing length be 1 millimeter
To 3 millimeters, and tapped through hole 331 can screwing length be equal to tapped through hole 331 depth.Due to plugging device 30 volume compared with
It is small, by tapped through hole 321 can screwing length be effectively arranged, can either guarantee on plugging device 30 and wirerope 4
The reliability of the connection of bolt, and can be avoided first sleeve 32 and excessively protruded from except network management 31 since length is too long, i.e.,
As shown in fig. 7, the bolt 41 of wirerope 4 can pass through tapped through hole 321, the incomplete thread of 41 tail portion of bolt is exposed at
It outside first sleeve 32, and is screwed completely by the complete thread section of the bolt 41 of wirerope 4 with tapped through hole 321, to have
Effect increase bolt 41 and first sleeve 32 screw depth, improve the reliability of threaded engagement.
One Preferable scheme is that, the first flange 323 of first sleeve 32, the second flange 332 of second sleeve 33 are in
Ring-type setting, and the diameter of the first flange 323 is greater than the diameter of the second flange 332.Because the second flange 332 is mainly used for net
The silk material 311 of pipe 31 is pressed together on the first flange 323, and the diameter of the first flange 323 is set greater than the second flange 332
Diameter can guarantee that the silk material 311 pressed is supported space with enough, and can guarantee that the first flange 323 itself can again
With enough bearing capacitys.
Gasket 34 is set on the auxiliary section 322 of first sleeve 32, also, gasket 4 is located at the circle of the first end of network management 31
Between hole 310 and the second flange 332, gasket 4 is pressed together between the first end of network management 31 and the second flange 332.Gasket 4 can
Play the role of carrying out stop to network management 31, network management 31 avoided to skid between the first flange 323 and the second flange 332 rotation,
Guarantee the reliability that network management 31 is installed.
To sum up, the first flange of first sleeve setting and the second flange of second sleeve setting can be set in circular hole
The first end for the network management set is fixed, i.e., is fixed to silk material boundling, and then avoid the occurrence of in the prior art
Need the problem of silk material boundling is fixed by welding.In addition, by the first flange and the second flange to silk material
The mode that boundling is fixed can effectively save silk material and occupy the space of first sleeve, and then first sleeve is greatly reduced
The length of the network management of prominent plugging device reduces the risk that thrombus generates and effectively reduces endothelial cell and climbs clad can.And in first set
Setting tapped through hole in cylinder middle part enables to the bolt on the wirerope connecting with plugging device that can be pierced by tapped through hole, both guarantees steel
There can be enough screwing lengths between the bolt and first sleeve of cable, and the prominent plugging device of first sleeve can be effectively reduced
Network management length, avoid the type of flow for influencing the original blood of human body, additionally it is possible to reduce cardiovascular organization and damage and scorching occurs
The probability of disease.
The production method embodiment of plugging device:
The production method of plugging device provided by the utility model is for the closure as described in the examples of above-mentioned plugging device
Device 30 is made, is processed, which includes:
The production of first sleeve:
First sleeve 32 is formed, and makes first sleeve 32 that there is auxiliary section 322 and be integrally formed with auxiliary section 322
The first flange 323, meanwhile, need to guarantee the thickness of the first flange 323 between 0.1 millimeter to 1 millimeter, and to first set
The processing that the middle part of cylinder 32 carries out the processing of tapped through hole 321, carries out the first screw thread to the peripheral wall of auxiliary section 322.
The production of second sleeve:
Second sleeve 33 is formed, so that second sleeve 331 has the second flange 332, meanwhile, guarantee the second flange
332 thickness between 0.1 millimeter to 1 millimeter, and to the middle part of second sleeve 33 carry out through-hole 331 and the second screw thread plus
Work.
The production of network management:
It is woven using more one metal wire materials or more macromolecule silk materials, forms network management 331 then for the of network management 31
One end is threaded, and shrinks the first end of network management 31 in circular hole 310, meanwhile, guarantee that the diameter of circular hole 310 is greater than auxiliary section
332 diameter, and diameter of the diameter less than the first flange 323 for guaranteeing circular hole 310 and the diameter less than the second flange 332.
The assembling of plugging device:
Network management 31 is socketed on the auxiliary section 322 of first sleeve 32 by circular hole 310, then, gasket 34 is sleeved on
On auxiliary section 322, and it is pressed together on gasket 34 in the first end of network management 31.Then, second sleeve 33 is sleeved on auxiliary section 322
On so that first sleeve 32 and second sleeve 33 carry out it is affixed, when first sleeve 32 and second sleeve 33 connection complete when, make net
The first end of pipe 31 is pressed together between the first flange 323 and gasket 34, and gasket 34 is made to be pressed together on the first end and of network management 31
Between two flanges 332.When first sleeve 32, the connection of second sleeve 33 are completed, laser is used in one end far from the first flange 332
Auxiliary section 322 and second sleeve 33 is welded and fixed in welding.
The molding of network management:
Network management 31 is placed in molding die carry out it is heat-treating profiled after, inside network management 31 suture or fill polyester dacron
Or plugging device can be made in the bluff bodys such as polytetrafluoroethylene (PTFE).
To sum up, the plugging device that the production method of plugging device provided by the utility model is produced, which can be avoided, to be showed
Have and need the problem of silk material boundling is fixed by welding in technology, and the silk material that can also save network management occupies
The space of first sleeve, and then the length of the network management of the prominent plugging device of first sleeve is greatly reduced, reduce the wind that thrombus generates
The dangerous and effective endothelial cell that reduces climbs clad can.In addition, designed by structure to first sleeve, can make and plugging device
Bolt on the wirerope of connection can be pierced by tapped through hole, both guarantee can have between the bolt of wirerope and first sleeve enough
Screwing length, and the length of the network management of the prominent plugging device of first sleeve can be effectively reduced, avoid influencing the original blood of human body
The type of flow, additionally it is possible to reduce cardiovascular organization occur damage and inflammation probability.
Finally it is emphasized that the above is only the preferred embodiment of the present invention, it is not limited to this reality
With novel, for those skilled in the art, the utility model can have various change and change, all in the utility model
Spirit and principle within, any modification, equivalent substitution, improvement and etc. done should be included in the protection model of the utility model
Within enclosing.
Claims (10)
1. plugging device, the network management surrounded including multi-filament material, which is characterized in that the plugging device further include:
First sleeve, is provided with tapped through hole in the middle part of the first sleeve, the first sleeve have auxiliary section and with it is described
Integrally formed first flange in auxiliary section, it is in circular hole that the first end opening of the network management, which is shunk, and the circular hole is socketed in described match
In conjunction portion, first flange with a thickness of 0.1 millimeter to 1 millimeter;
Second sleeve, the second sleeve are sleeved on the auxiliary section, and the first end of the network management is pressed on described first
Between flange and the second sleeve.
2. plugging device according to claim 1, it is characterised in that:
One end of the second sleeve towards first flange is provided with the second flange, and the first end of the network management is pressed on
Between first flange and second flange.
3. plugging device according to claim 2, it is characterised in that:
The plugging device further includes gasket, and the gasket is sleeved on the auxiliary section, and the gasket is located at the circular hole and institute
It states between the second flange, and the gasket is pressed together in the first end of the network management.
4. plugging device according to claim 3, it is characterised in that:
It is provided with the first screw thread on the peripheral wall of the auxiliary section, is provided with the second screw thread in the middle part of the second sleeve, described
One screw thread and second threaded engagement.
5. plugging device according to claim 4, it is characterised in that:
Screwing length between first screw thread and second screw thread is 0.5 millimeter to 3 millimeters.
6. plugging device according to claim 5, it is characterised in that:
The tapped through hole can screwing length be 1 millimeter to 3 millimeters, and the tapped through hole can screwing length be equal to it is described
The depth of tapped through hole.
7. plugging device according to claim 6, it is characterised in that:
The auxiliary section is provided with welding structure in one end far from first flange with the second sleeve.
8. plugging device according to claim 2, it is characterised in that:
Second flange with a thickness of 0.1 millimeter to 1 millimeter.
9. plugging device according to claim 8, it is characterised in that:
The diameter of first flange is greater than the diameter of second flange.
10. plugging device according to any one of claims 1 to 9, it is characterised in that:
The network management is internally provided with polyester dacron or polytetrafluoroethylene (PTFE).
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CN201820918827.4U CN208905664U (en) | 2018-06-13 | 2018-06-13 | Plugging device |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108714038A (en) * | 2018-06-13 | 2018-10-30 | 广东脉搏医疗科技有限公司 | Plugging device and preparation method thereof |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108714038A (en) * | 2018-06-13 | 2018-10-30 | 广东脉搏医疗科技有限公司 | Plugging device and preparation method thereof |
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