CN208893461U - A kind of radioactive particle chain - Google Patents

A kind of radioactive particle chain Download PDF

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Publication number
CN208893461U
CN208893461U CN201820946425.5U CN201820946425U CN208893461U CN 208893461 U CN208893461 U CN 208893461U CN 201820946425 U CN201820946425 U CN 201820946425U CN 208893461 U CN208893461 U CN 208893461U
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China
Prior art keywords
particle chain
particle
radioactive
tube body
chain
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CN201820946425.5U
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Inventor
田素青
王俊杰
孙海涛
姜玉良
范京红
张喜乐
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Peking University Third Hospital
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Peking University Third Hospital
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Abstract

The utility model relates to radiation treatment seeds implanted equipment, more particularly to a kind of radioactive particle chain, including particle chain tube body, it is offered on the particle chain tube body multiple for placing the groove of radioactive particle, the groove is distributed on the particle chain tube body, is placed with radioactive particle at least one described groove.The particle chain tube body carries out 3D printing using degradable polyphosphazene polymer lactic acid substrate and forms.The radioactive particle chain of the utility model can be avoided radioactive particle displacement and migration, avoid the cold spot of tumor area radiological dose and hot spot from occurring, to be beneficial to clinical radiation particle close-range treatment.

Description

A kind of radioactive particle chain
Technical field
The utility model relates to radiation treatment seeds implanted equipment, more specifically a kind of radioactive particle chain.
Background technique
Radioactive particle Interstitial brachytherapy tumour has more than 100 years history.Early stage radioactive particle treats tumour High-energy radioactive nucleic, such as radium -225 are used, these nucleic discharge gamma ray, and penetration power is strong, is not easy to protect.Nearly 20 Year due to low energy nucleic, such as iodine-125, palladium -103 is succeeded in developing, Computerized three-dimensional treatment planning systems and image-guidance system Occur, radioactive particle treatment tumour is made to become one of accurate treatment means.
However there is also some defects in the prior art, for example, the length and spacing of radioactive particle chain are not easy to control;It puts Penetrating property particle volume is short and small, is easily displaced and migrates, and causes tumor area radiological dose cold spot and hot spot, or even occurs moving at a distance Position, affects the whole curative effect of the close-range treatment of clinical radiation particle.
Utility model content
In order to solve the technical problems mentioned in the background technology, the utility model provides a kind of radioactive particle chain, should Radioactive particle chain can be avoided radioactive particle displacement and migration, and the cold spot of tumor area radiological dose and hot spot is avoided to occur, To be beneficial to clinical radiation particle close-range treatment.
The technical scheme adopted by the utility model is
A kind of radioactive particle chain, including particle chain tube body offer on the particle chain tube body multiple for putting The groove of penetrating property particle, the groove are distributed on the particle chain tube body, are placed at least one described groove Penetrating property particle.
Since radioactive particle is located in groove, radioactive particle displacement and migration are avoided, tumor area radiological agent is avoided The cold spot and hot spot of amount occur, to be beneficial to clinical radiation particle close-range treatment.
In above-mentioned radioactive particle chain, the particle chain tube body carries out 3D using degradable polyphosphazene polymer lactic acid substrate It prints.
In above-mentioned radioactive particle chain, the particle chain tube body includes multiple particles chain monomer, each particle chain The groove for placing radioactive particle is provided on monomer;There is step, institute in the tube wall of particle chain monomer one end Stating the particle chain monomer other end has the plug being inserted into the step;Using slotting between multiple particle chain monomers Head, which is inserted into step to be sequentially connected with, constitutes the particle chain tube body.
In above-mentioned radioactive particle chain, the position that the plug is connected with step is bonded using glue layer.
In above-mentioned radioactive particle chain, the particle chain tube body being made of the particle chain monomer, wherein adjacent The groove of the particle chain monomer is in staggered distribution in the circumferential.
The groove of the above-mentioned adjacent particle chain monomer is in staggered distribution in the circumferential, that is, is connecting two adjacent grains When subchain monomer, one angle of relative rotation, the groove section figure of two adjacent particle chain monomers are staggered groove in the circumferential Distribution, after implantation can Omnidirectional radiation or according to treatment need consciously rotating gravure towards specifically being treated.
In above-mentioned radioactive particle chain, the radioactive particle is I-125 seeds.
The technical effect of the utility model is as follows:
The radioactive particle chain of the utility model has groove, and radioactive particle is located in groove, works as radioactive particle chain It is not easy to migrate after implantation;Radioactive particle has certain half-life period, and degradable polyphosphazene polymer lactic acid substrate can be with particle Decay gradually absorbs, and normal tissue is not influenced after treatment end, specifically, the intermediate product of polyphosphazene polymer lactic acid degradation in vivo It is lactic acid, and lactic acid is normal metabolite in human body, is finally degraded to carbon dioxide and water, it is harmless to the human body, to group Knit no accumulation;Radioactive particle chain can be improved procedure efficiency simultaneously.
Detailed description of the invention
In order to illustrate the embodiment of the utility model or the technical proposal in the existing technology more clearly, below will be to embodiment Or attached drawing needed to be used in the description of the prior art is briefly described, it should be apparent that, the accompanying drawings in the following description is only It is some embodiments of the utility model, for those of ordinary skill in the art, in the premise not made the creative labor Under, it is also possible to obtain other drawings based on these drawings.
Fig. 1 is the structural schematic diagram of one embodiment of the utility model;
Fig. 2 is the structural schematic diagram of the utility model another embodiment;
Fig. 3 is the structural schematic diagram of particle chain monomer in Fig. 2.
The reference numerals are as follows:
1, particle chain tube body;2, groove;3, particle chain monomer;4, step;5, plug.
Specific embodiment
To keep the purpose of this utility model, technical solution and advantage clearer, below by the technology to the utility model Scheme is described in detail.Obviously, the described embodiments are only a part of the embodiments of the utility model, rather than all Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are not before making creative work Obtained all other embodiment is put, the range that the utility model is protected is belonged to.
As shown in Figure 1, the utility model provides a kind of radioactive particle chain, including particle chain tube body 1, the particle chain pipe Multiple grooves 2 for being used to place radioactive particle are offered on body 1, the groove 2 is distributed in the particle chain tube body 1 On, radioactive particle (not shown) is placed at least one described groove 2.
Since radioactive particle is located in groove 2, radioactive particle displacement and migration are avoided, tumor area radiological agent is avoided The cold spot and hot spot of amount occur, to be beneficial to clinical radiation particle close-range treatment.
In above-mentioned radioactive particle chain, the particle chain tube body carries out 3D using degradable polyphosphazene polymer lactic acid substrate It prints.
As shown in Figures 2 and 3, the particle chain tube body 1 includes multiple particles chain monomer 3, each particle chain monomer 3 On be provided with groove 2 for placing radioactive particle;There is step 4 in the tube wall of described 3 one end of particle chain monomer, it is described 3 other end of particle chain monomer has the plug 5 being inserted into the step 4;It is used between multiple particle chain monomers 3 Plug 5, which is inserted into step 4 to be sequentially connected with, constitutes the particle chain tube body 1.
In above-mentioned radioactive particle chain, the position that the plug 5 is connected with step 4 is bonded using glue layer.
In above-mentioned radioactive particle chain, the particle chain tube body 1 being made of the particle chain monomer 3, wherein adjacent The groove 2 of the particle chain monomer 3 be in staggered distribution in the circumferential.
The groove of the above-mentioned adjacent particle chain monomer is in staggered distribution in the circumferential, that is, is connecting two adjacent grains When subchain monomer, one angle of relative rotation, the groove section figure of two adjacent particle chain monomers are staggered groove in the circumferential Distribution, after implantation can Omnidirectional radiation or according to treatment need consciously rotating gravure towards specifically being treated.
The structure of the particle chain monomer 3 may be replaced by one end with plug, the inner hollow diameter and plug of the other end Major diameter fit connection, the step structure of the other end can cancel.It should also be noted that, the end of the particle chain tube body is Enclosed construction, have Closed end plate, the Closed end plate can be used with particle chain tube body be integrally formed (or be located at end particle Chain monomer is integrally formed).
The application method of the radioactive particle chain of the utility model: before radioactive particle chain implantation, computer three is utilized It ties up treatment planning systems and formulates preoperative plan, plan in art, i.e., according to tumor size, range of tumor, radiotherapy susceptibility and surrounding Whether have and jeopardize the determining therapeutic dose such as organ, and number of particles and radioactive particle are determined by interparticle distance and particle chain spacing The quantity of chain, and then determine therapeutic dose, prepare radioactive particle chain.3d prints particle chain;Image association template punctures, implantation Particle chain.
Wherein the preparation of radioactive particle chain can use 3d printing technique, directly print entire particle chain tube body, It then can also be selected according to the spacing of radioactive particle at each using the consistent particle chain monomer of specification is printed in advance Place a radioactive particle in the groove of particle chain monomer, or selection is separated by several particle chain monomers and places one again and puts Penetrating property particle, the independence selected in this way increase, can produce particle chain monomer in batches, can also make to avoid 3d Method of printing The limitation of radioactive particle chain can also carry out production particle using existing other way (such as by the way of hot melt after-pouring) Chain monomer.
Above description is only a specific implementation of the present invention, but the protection scope of the utility model is not limited to In this, anyone skilled in the art within the technical scope disclosed by the utility model, can readily occur in variation Or replacement, it should be covered within the scope of the utility model.Therefore, the protection scope of the utility model should be with the power Subject to the protection scope that benefit requires.

Claims (6)

1. a kind of radioactive particle chain, which is characterized in that including particle chain tube body, offer multiple use on the particle chain tube body In the groove for placing radioactive particle, the groove is distributed on the particle chain tube body, at least one described groove It is placed with radioactive particle.
2. radioactive particle chain according to claim 1, which is characterized in that the particle chain tube body uses degradable height Molecule polylactic acid substrate carries out 3D printing and forms.
3. radioactive particle chain according to claim 2, which is characterized in that the particle chain tube body includes multiple particles chain Monomer is provided with the groove for placing radioactive particle on each particle chain monomer;Particle chain monomer one end Tube wall in there is step, the particle chain monomer other end has the plug that is inserted into the step;It is multiple described It is inserted into step to be sequentially connected with using plug between particle chain monomer and constitutes the particle chain tube body.
4. radioactive particle chain according to claim 3, which is characterized in that the position that the plug is connected with step uses Glue layer bonding.
5. radioactive particle chain according to claim 3 or 4, which is characterized in that the institute being made of the particle chain monomer Particle chain tube body is stated, wherein the groove of the adjacent particle chain monomer is in staggered distribution in the circumferential.
6. radioactive particle chain according to claim 1, which is characterized in that the radioactive particle is I-125 seeds.
CN201820946425.5U 2018-06-20 2018-06-20 A kind of radioactive particle chain Active CN208893461U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201820946425.5U CN208893461U (en) 2018-06-20 2018-06-20 A kind of radioactive particle chain

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201820946425.5U CN208893461U (en) 2018-06-20 2018-06-20 A kind of radioactive particle chain

Publications (1)

Publication Number Publication Date
CN208893461U true CN208893461U (en) 2019-05-24

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Family Applications (1)

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Country Status (1)

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CN (1) CN208893461U (en)

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