CN208809882U - A kind of production emulsifying machine for emulsification process for bird flu vaccine - Google Patents
A kind of production emulsifying machine for emulsification process for bird flu vaccine Download PDFInfo
- Publication number
- CN208809882U CN208809882U CN201821361818.6U CN201821361818U CN208809882U CN 208809882 U CN208809882 U CN 208809882U CN 201821361818 U CN201821361818 U CN 201821361818U CN 208809882 U CN208809882 U CN 208809882U
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- Prior art keywords
- gear
- shaft
- tank body
- bearing
- bird flu
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000001804 emulsifying effect Effects 0.000 title claims abstract description 44
- 238000004945 emulsification Methods 0.000 title claims abstract description 43
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 39
- 238000000034 method Methods 0.000 title claims abstract description 39
- 206010064097 avian influenza Diseases 0.000 title claims abstract description 37
- 241000371980 Influenza B virus (B/Shanghai/361/2002) Species 0.000 title claims abstract description 35
- 238000007789 sealing Methods 0.000 claims description 14
- 238000010008 shearing Methods 0.000 abstract description 8
- 238000010586 diagram Methods 0.000 description 4
- 229960003971 influenza vaccine Drugs 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 208000002979 Influenza in Birds Diseases 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
Landscapes
- Mixers Of The Rotary Stirring Type (AREA)
Abstract
The utility model discloses a kind of production emulsifying machine for emulsification process for bird flu vaccine, belong to mulser field, a kind of production emulsifying machine for emulsification process for bird flu vaccine disclosed by the utility model, including motor, shaft, tank body, reversion cylinder, motor is fixed on the top of the tank body, and the power output end of motor and one end of shaft connect, and the roof of shaft and tank body is rotatablely connected, the roof of one end and tank body for inverting cylinder is rotatablely connected, and shaft is located at the inside of reversion cylinder;It further include first gear, second gear, internal gear, first gear is fixed in shaft, and one end of second gear and the roof of tank body are rotatablely connected, first gear and second gear engagement connection, internal gear is fixed on the inner sidewall of reversion cylinder, and second gear engages connection with internal gear.By the blade high speed rotation of shaft, while cylinder reverse rotation is inverted, big shearing force is formed using biggish relative velocity, so that emulsifying effectiveness is more preferable.
Description
Technical field
The utility model relates to mulser field more particularly to a kind of production emulsifying machine for emulsification process for bird flu vaccine.
Background technique
Emulsification is the important link of oil emu avian influenza vaccine production.Emulsification is to mix water phase and oil, is then passed through
High shear force formed Water-In-Oil dosage form lotion process, wherein water phase is made of antigenic solution and Tween-80, oil be mutually by
What white oil and Si Ben -80 were formed, in actual production, they are entered in emulsion tank by respective pipeline, then pass through cream
Change the high shear force that head generates, water phase is made mutually to form uniform Water-In-Oil dosage form lotion with oil, it is final to generate oil emu fowl stream
Influenza vaccine.It can be seen that the quality of emulsifying effectiveness, determines the length of vaccine quality and shelf-life.Therefore, emulsifying process is also
The key link of oil emu avian influenza vaccine production.At present in experimental study, small sample is carried out using small-sized mulser substantially
Test;And in large-scale industrial production, similar emulsifying device is used substantially.
A kind of production emulsification process for bird flu vaccine emulsification disclosed in Chinese patent literature publication number CN202006096U
Machine, including motor, sealing ring, main shaft, rack, coupling band and homogeneous head, motor are fixed on the tank deck of emulsion tank, sealing ring
Be fixedly connected with rack, sealing ring is fixedly connected by bolt and emulsion tank tank deck, rack at cylindrical shape, main shaft through
Machine frame inside is provided with coupling band between upper rack and frame lower, coupling band is fixedly connected with rack, and homogeneous head is by rotor
It is formed with stator, rotor is less than the height of stator close to the center of homogeneous head, center of the stator far from homogeneous head, the height of rotor
Degree, rotor are fixed on main shaft, and rotor is made of 3 blades, and 3 blades are at helical structure;Stator is fixed on the rack, fixed
Son is rectangular parallelepiped structure, and all stator distributions on the same circumference, there is gap between stator and stator.Existing mulser stirs
Mix capitiform at shearing force it is big not enough, emulsifying effectiveness is not also fine.
Utility model content
In order to overcome the drawbacks of the prior art, the technical problem to be solved by the utility model is to propose a kind of production fowl
Influenza vaccines emulsifying process mulser by the blade high speed rotation of shaft, while inverting cylinder reverse rotation, and utilization is biggish
Relative velocity forms big shearing force, so that emulsifying effectiveness is more preferable.
For this purpose, the utility model uses following technical scheme:
A kind of production emulsifying machine for emulsification process for bird flu vaccine provided by the utility model, including tank body, shaft and anti-
Rotating cylinder;Reversion cylinder, shaft are respectively positioned on the inside of tank body, and the top on the top and tank body that invert cylinder is rotatably connected, the top of shaft
End is rotatably connected across tank body, and with the top of tank body, and shaft is located at the inside of reversion cylinder, the direction of rotation of shaft and reversion
The direction of rotation of cylinder is opposite.
The bottom end of shaft is provided with several blades, and the lower part for inverting cylinder is provided with housing, and several blades are located at housing
It is interior.
The utility model preferably technical solution is that production emulsifying machine for emulsification process for bird flu vaccine further includes first
Gear, second gear and internal gear;
First gear is fixed in shaft, and internal gear is fixed on the inner sidewall of reversion cylinder, and second gear is located at the first tooth
In gap between wheel and internal gear, in second gear close to shaft side, second gear is meshed with first gear, second
Gear is meshed far from shaft side, second gear with internal gear.
The utility model preferably technical solution is that production emulsifying machine for emulsification process for bird flu vaccine further includes second
Bearing and gear shaft;Second bearing is fixed on the roof of tank body, and one end and the second bearing of gear shaft are rotatably connected,
It is fixedly connected in the middle part of the other end and second gear.
The utility model preferably technical solution is that production emulsifying machine for emulsification process for bird flu vaccine further includes first
Bearing;First bearing is fixed on the roof of tank body, and shaft passes through first bearing, and is rotatably connected with first bearing.
The utility model preferably technical solution is that production emulsifying machine for emulsification process for bird flu vaccine further includes third
Bearing;3rd bearing is fixed on the roof of tank body, and first bearing is located at the inside of 3rd bearing, inverts the top and first of cylinder
Bearing is rotatably connected.
The utility model preferably technical solution is that housing is configured to porous fine mesh structure.
The utility model preferably technical solution is that production emulsifying machine for emulsification process for bird flu vaccine further includes sealing
Lantern ring;Sealing ring is socketed in shaft, and the outer wall of sealing ring is fixedly connected with the roof of tank body.
The utility model preferably technical solution is that production emulsifying machine for emulsification process for bird flu vaccine further includes electricity
Machine;Motor is fixed on the top of tank body, and the power output end of motor and the top of shaft connect.
The utility model preferably technical solution is that production emulsifying machine for emulsification process for bird flu vaccine further includes shell
Body;Tank body is fixed in outer housing, and there are gap between tank body and outer housing, inner space is hydraulically full.
The utility model preferably technical solution is that production emulsifying machine for emulsification process for bird flu vaccine further includes at least
Two supporting legs;At least two supporting leg is both secured to the bottom of outer housing.
The utility model has the following beneficial effects:
A kind of production emulsifying machine for emulsification process for bird flu vaccine provided by the utility model, first gear are fixed on shaft
On, one end of second gear and the roof of tank body are rotatablely connected, and first gear and second gear engagement connection, internal gear are fixed on
On the inner sidewall for inverting cylinder, second gear engages connection with internal gear.By the blade high speed rotation of shaft, while it is anti-to invert cylinder
To rotation, big shearing force is formed using biggish relative velocity, so that emulsifying effectiveness is more preferable.
Detailed description of the invention
Fig. 1 is the overall structure diagram provided in specific embodiment of the present invention;
Fig. 2 is the schematic diagram of the gear installation provided in specific embodiment of the present invention;
Fig. 3 is the structural schematic diagram of the cover net and blade that provide in specific embodiment of the present invention;
Fig. 4 is the bottom substance schematic diagram of the cover net and blade that provide in specific embodiment of the present invention;
In figure:
1, tank body;2, cylinder is inverted;3, shaft;4, motor;5, outer housing;51, liquid;6, supporting leg;31, blade;21, it covers
Net;71, first gear;72, second gear;721, gear shaft;73, internal gear;81,3rd bearing;82, first bearing;83,
Two bearings;9, sealing ring.
Specific embodiment
Further illustrate the technical solution of the utility model below with reference to the accompanying drawings and specific embodiments.
As shown in Figure 1, Figure 2, Figure 3 shows, a kind of production emulsifying machine for emulsification process for bird flu vaccine provided in the present embodiment,
Including tank body 1, shaft 3 and reversion cylinder 2;Reversion cylinder 2, shaft 3 are respectively positioned on the inside of tank body 1, invert top and the tank body 1 of cylinder 2
Top be rotatably connected, the top of shaft 3 passes through tank body 1, and is rotatably connected with the top of tank body 1, and shaft 3 is located at reversion
The direction of rotation of the inside of cylinder 2, shaft 3 is opposite with the reversion direction of rotation of cylinder 2.By 31 high speed rotation of blade of shaft 3, together
Shi Fanzhuan cylinder 2 reversely rotates, and big shearing force is formed using biggish relative velocity, so that emulsifying effectiveness is more preferable.
Further, the bottom end of shaft 3 is provided with several blades 31, and the lower part of reversion cylinder 2 is provided with housing, if cured leaf
Piece 31 is located in housing.It is driven by blade 31 so that oil is mutually increased with water phase collision opportunity, so that emulsification more refinement
It is greasy.
Further, production emulsifying machine for emulsification process for bird flu vaccine further include first gear 71, second gear 72, with
And internal gear 73, first gear 71 are fixed in shaft 3, internal gear 73 is fixed on the inner sidewall of reversion cylinder 2, second gear 72
In gap between first gear 71 and internal gear 73, in second gear 72 close to 3 side of shaft, second gear 72 and
One gear 71 is meshed, and in second gear 72 far from 3 side of shaft, second gear 72 is meshed with internal gear 73.Motor 4 drives
Shaft 3 rotates, while under the engagement of first gear 71 and second gear 72, and second gear 72 and shaft 3 reversely rotate, simultaneously
Second gear 72 is engaged with internal gear 73, so that second gear 72 and reversion 2 rotating Vortex of cylinder, so that shaft 3 and reversion
Cylinder 2 rotates backward, so that big shearing force is generated, so that emulsifying effectiveness is more preferably.
In order to which second gear 72 is preferably fixed, production emulsifying machine for emulsification process for bird flu vaccine further includes the second axis
Hold 83 and gear shaft 721;Second bearing 83 is fixed on the roof of tank body 1, and one end of gear shaft 721 and second bearing 83 can
Rotation connection, the other end are fixedly connected with the middle part of second gear 72.So that under the action of second bearing 83, second gear
72 can preferably rotate.
In order to enable shaft 3 more preferably rotates, production emulsifying machine for emulsification process for bird flu vaccine further includes first bearing 82;
First bearing 82 is fixed on the roof of tank body 1, and shaft 3 passes through first bearing 82, and is rotatably connected with first bearing 82.
Further, production emulsifying machine for emulsification process for bird flu vaccine further includes 3rd bearing 81;3rd bearing 81 is solid
It is scheduled on the roof of tank body 1, first bearing 82 is located at the inside of 3rd bearing 81, and the top and first bearing 82 for inverting cylinder 2 can
Rotation connection.So that reversion cylinder 2 can be with flexible rotating.
As shown in figure 4, further, housing is configured to porous fine mesh structure.So that more net pore structures more preferably provide
Shearing force, when liquid 51 enters in foraminous shield net 21, hole can provide the progress that a shearing force promotes emulsification.
Further, production emulsifying machine for emulsification process for bird flu vaccine further includes sealing ring 9;Sealing ring 9 is socketed
In in shaft 3, the outer wall of sealing ring 9 is fixedly connected with the roof of tank body 1.Sealing ring inside tank body 1 to be sealed environment,
Avoid the entrance of bacterium.
Further, production emulsifying machine for emulsification process for bird flu vaccine further includes motor 4;Motor 4 is fixed on tank body 1
The power output end at top, motor 4 is connect with the top of shaft 3.It can be very good to provide power to shaft 3 by motor 4, drive
Movable vane piece 31 rotates.
In order to preferably control the interior space temperature of emulsification instrument, production emulsifying machine for emulsification process for bird flu vaccine is also wrapped
Include outer housing 5;Tank body 1 is fixed in outer housing 5, and there are gap, inner spaces hydraulically full 51 between tank body 1 and outer housing 5.
Emulsification instrument interior space temperature can be made preferably to regulate and control by the liquid 51 flowed between gap.
Further, production emulsifying machine for emulsification process for bird flu vaccine further includes two supporting legs 6;Two supporting legs 6
It is both secured to the bottom of outer housing 5.Emulsification instrument can be made preferably to be placed in ground by the effect of supporting leg 6.
The utility model is described with reference to the preferred embodiments, and those skilled in the art know, is not departing from this reality
In the case where with novel spirit and scope, various changes or equivalence replacement can be carried out to these features and embodiment.This reality
It is not limited to the particular embodiment disclosed with novel, other embodiments fallen into claims hereof all belong to
In the range of the utility model protection.
Claims (10)
1. a kind of production emulsifying machine for emulsification process for bird flu vaccine, it is characterised in that:
Including tank body (1), shaft (3) and reversion cylinder (2);
Reversion cylinder (2), shaft (3) are respectively positioned on the inside of the tank body (1), the top of reversion cylinder (2) and the tank
The top of body (1) is rotatably connected, and the top of the shaft (3) passes through the tank body (1), and the top with the tank body (1)
It is rotatably connected, the shaft (3) is located at the inside of reversion cylinder (2), the direction of rotation of the shaft (3) and the reversion
The direction of rotation of cylinder (2) is opposite;
The bottom end of the shaft (3) is provided with several blades (31), and the lower part of reversion cylinder (2) is provided with housing (21),
Several blades (31) are located in the housing (21).
2. production emulsifying machine for emulsification process for bird flu vaccine according to claim 1, it is characterised in that:
It further include first gear (71), second gear (72) and internal gear (73);
The first gear (71) is fixed on the shaft (3), and the internal gear (73) is fixed on the interior of reversion cylinder (2)
On side wall, the second gear (72) is located in the gap between first gear (71) and the internal gear (73), described
Two gears (72) are close to the shaft (3) side, and the second gear (72) is meshed with the first gear (71), described
Second gear (72) is meshed far from the shaft (3) side, the second gear (72) with the internal gear (73).
3. production emulsifying machine for emulsification process for bird flu vaccine according to claim 2, it is characterised in that:
It further include second bearing (83) and gear shaft (721);
The second bearing (83) is fixed on the roof of the tank body (1), one end and described second of the gear shaft (721)
Bearing (83) is rotatably connected, and is fixedly connected in the middle part of the other end and the second gear (72).
4. production emulsifying machine for emulsification process for bird flu vaccine according to claim 1, it is characterised in that:
It further include first bearing (82);
The first bearing (82) is fixed on the roof of the tank body (1), and the shaft (3) passes through the first bearing
(82), it and with the first bearing (82) is rotatably connected.
5. production emulsifying machine for emulsification process for bird flu vaccine according to claim 4, it is characterised in that:
It further include 3rd bearing (81);
The 3rd bearing (81) is fixed on the roof of the tank body (1), and the first bearing (82) is located at the third axis
The inside of (81) is held, the top of reversion cylinder (2) is rotatably connected with the first bearing (82).
6. production emulsifying machine for emulsification process for bird flu vaccine according to claim 1, it is characterised in that:
The housing (21) is configured to porous fine mesh structure.
7. production emulsifying machine for emulsification process for bird flu vaccine according to claim 1, it is characterised in that:
It further include sealing ring (9);
The sealing ring (9) is socketed on the shaft (3), the outer wall of the sealing ring (9) and the top of the tank body (1)
Wall is fixedly connected.
8. production emulsifying machine for emulsification process for bird flu vaccine according to claim 1, it is characterised in that:
It further include motor (4);
The motor (4) is fixed on the top of the tank body (1), power output end and the shaft (3) of the motor (4)
Top connection.
9. production emulsifying machine for emulsification process for bird flu vaccine according to claim 1, it is characterised in that:
It further include outer housing (5);
The tank body (1) is fixed in the outer housing (5), there are gap between the tank body (1) and the outer housing (5),
The inner space is hydraulically full (51).
10. production emulsifying machine for emulsification process for bird flu vaccine according to claim 9, it is characterised in that:
It further include at least two supporting leg (6);
At least two supporting leg (6) is both secured to the bottom of the outer housing (5).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201821361818.6U CN208809882U (en) | 2018-08-23 | 2018-08-23 | A kind of production emulsifying machine for emulsification process for bird flu vaccine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201821361818.6U CN208809882U (en) | 2018-08-23 | 2018-08-23 | A kind of production emulsifying machine for emulsification process for bird flu vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
CN208809882U true CN208809882U (en) | 2019-05-03 |
Family
ID=66274315
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201821361818.6U Expired - Fee Related CN208809882U (en) | 2018-08-23 | 2018-08-23 | A kind of production emulsifying machine for emulsification process for bird flu vaccine |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN208809882U (en) |
-
2018
- 2018-08-23 CN CN201821361818.6U patent/CN208809882U/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
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GR01 | Patent grant | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190503 |
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CF01 | Termination of patent right due to non-payment of annual fee |