CN208808624U - A kind of individuation bone defect filling metal internal fixation device - Google Patents
A kind of individuation bone defect filling metal internal fixation device Download PDFInfo
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- CN208808624U CN208808624U CN201820822944.0U CN201820822944U CN208808624U CN 208808624 U CN208808624 U CN 208808624U CN 201820822944 U CN201820822944 U CN 201820822944U CN 208808624 U CN208808624 U CN 208808624U
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Abstract
The utility model discloses a kind of individuation bone defect filling metal internal fixation devices, the internal fixation device is the titanium prosthesis by 3D printing, the prosthese is internally provided with several first through hole, and outer surface is provided with several second through-holes, which also includes the third through-hole through prosthese.The utility model passes through preoperative Overall Acquisition bone grafting layer image, three-dimensional reconstruction, simulate the parameters of internal fixation device, after the installation of simulated implementation perfect matching, it is easy to accomplish consistent with the form height in bone defect region by the internal fixation device of 3D printer printing preparation, and facilitate and to form specific microcellular structure, it is able to achieve counterweight, implants-bone interface Bone Ingrowth and is connected and fixed, to realize the long-time stability of implant.And the elasticity modulus of the titanium alloy used and normal bone are close, have good supporting role；It is fixed by lock screw, is conducive to the initial stability for enhancing implant, the bone defect suitable for each position of Whole Body is implanted into.
Description
Technical field
It is filled the utility model relates to medical implants more particularly to a kind of individuation bone defect and uses metal internal fixation device,
The internal fixation device is that a kind of have both supports the bone defect 3D printing of fixed and Bone Ingrowth ability to be implanted into body.
Background technique
Bone defect caused by the reasons such as wound, inflammation and bone tumour is difficult to itself healing, and treatment is based on bone collection at present.
Clinically used bone grafting material includes autologous bone, homogeneous allogenic bone and synthetic polymer etc..Autologous bone transplanting is immune
Rejection is small, but its limited source, and the different degrees of complication such as infection often occur for the area Qie Gonggu；Homogeneous allogenic bone transplantation lures
The immunological rejection of hair is obvious in a wide range of bone defect；Synthetic polymer wide variety, there are immune rows
Reprimand reaction, and price is higher.Moreover, above-mentioned bone-grafting material is controlled general lack of initial support intensity in order to prevent fracture
It is still necessary to use the effective biomechanics of bone support of the fixing means such as plate screw progress when treating bone defect.However, since various diseases are led
There is uncertainty in the bone defect form of cause, the bone that traditional fixation material is difficult to perfect matching individual patients different shape lacks
Damage.
As 3D printing technique reaches its maturity, the application in medical domain, especially hard tissue repair field has been obtained
Major progress.Three-dimensional reconstruction is carried out to bone defect area based on image technology and Computer-aided Design Technology, utilizes 3D printing skill
Art prepares individuation and is implanted into internal fixation device, improves the accuracy and safety of hand immediate postoperative mechanical stability, operation.
However, how the intracavitary implantation internal fixation device of individuation bone defect has both mechanical stability and life when rebuilding bone defect
Object compatibility meets the Bone Ingrowth of later period implant while providing good initial support and stablizing, is the utility model
Important topic urgently to be resolved.
Utility model content
The purpose of this utility model is to provide a kind of intracavitary 3D printing individuation internal fixation device of bone defect, have good
Mechanical support and initial stability, while guaranteeing the effective Bone Ingrowth of later period implants-bone interface；Enable the patient to early stage health
It is multiple to take exercise, and medium-long term curative effect is excellent, limbs form caused by being suitably applied because of wound, inflammation or bone tumour it is irregular and
The reparation of the biggish bone defect of volume is also suitably applied the reparation of the irregular bones defects such as cranium jaw face, has important clinic
Application value.
In order to achieve the above object, the utility model provides a kind of individuation bone defect filling metal internal fixation device,
The internal fixation device is the titanium prosthesis by 3D printing, which is internally provided with several first through hole, outer surface setting
There are several second through-holes, which also includes the third through-hole through prosthese.
Preferably, the porosity of the first through hole and aperture be computer according to the density of bone defect position diaphysis and
Volume calculates setting, so that prosthese is consistent with the diaphysis weight at position to be filled.
Preferably, second through-hole is set according to the needs of Bone Ingrowth.
Preferably, the porosity of the second through-hole is 50-80%, aperture is 400 μm -800 μm, preferably 500-600 μm of aperture.
Preferably, the third through-hole is screw hole for attachment screw that prosthese and position to be filled is fixed, packet
Hole containing plain screw and screw hole.
Preferably, the titanium prosthesis is processed through stem cell, pre-formed Bone Ingrowth.
The invention also discloses a kind of preparations according to above-mentioned individuation bone defect filling metal internal fixation device
Method, this method include step in detail below:
Step 1, it carries out preoperative conventional image to check, acquires data, and import processing system；
Step 2, data processing is carried out, range and the boundary of bone defect are calculated；
Step 3, based on Modern Imaging Technique and Computer-aided Design Technology to the bone defect area of specific needs reparation into
Row three-dimensional reconstruction obtains the parameters of internal fixation device, includes first through hole, the aperture of the second through-hole and third through-hole and hole
Rate；
Step 4, using 3D printer, index internal fixation device is printed according to above-mentioned parameter.
Preferably, the imageological examination includes x-ray, CT (Computed Tomography) and nuclear magnetic resonance
(MRI) it checks.MRI is called nmr imaging technique, is a kind of using core mainly as caused by nuclear spin motion
The newest medical image new technology of magnetic resonance principle, to brain, thyroid gland, liver, gallbladder, spleen, kidney, pancreas, adrenal gland, uterus, ovary, preceding
The organa parenchymatosums such as column gland and Heart and great blood vessel have excellent diagnostic function.Compared with other auxiliary examination methods, MRI has
The advantages that imaging parameters are more, scanning speed is fast, tissue high resolution and image is apparent, can help doctor's " seeing " not noticeable
Early lesion, have become the sharp weapon of tumour, heart disease and cranial vascular disease early screening at present.MRI is water proton imaging,
Change the spin direction of water proton ambient electron, the proton imaging then generated by this principle using externally-applied magnetic field.CT belongs to
It is imaged in density, is after penetrating human body by X-ray, it is different to the absorptivity of ray because human body different tissues density is different,
Pass through the image for the density difference that after-treatment system generates.Advantage is to check that speed is fast, and density resolution is good.
Preferably, this method also includes: titanium prosthesis being carried out stem cell processing, carries out Bone Ingrowth pretreatment.
The utility model additionally provides a kind of purposes according to above-mentioned individuation bone defect filling metal internal fixation device,
It is characterized in that, bone defect of the internal fixation device for each position of whole body of human body and other mammalian bodies outside human body is planted
Enter.
3D printing implant provided by the utility model has the advantage that (1) uses the implantation of 3D printing technique preparation
Body can be accomplished consistent with the form height in bone defect region, use titanium alloy material to prepare, elasticity modulus and normal bone
Bone is close, has good supporting role；It (2) can be according to the different parts of bone defect and the need of fixing intensity inside implant
Personalized screw hole design is carried out, is fixed by lock screw, the initial stability for enhancing implant is conducive to；(3) 3D is beaten
Print technique can make implant surfaces design to form microcellular structure, and suitable porosity and aperture are conducive to implants-bone interface
Bone Ingrowth, to ensure the long-time stability of implant.
Detailed description of the invention
Fig. 1 a is the bone grafting layer preoperative planning CT view of the utility model.
Fig. 1 b is the bone grafting layer preoperative planning MRI view of the utility model.
Fig. 2 a is that the status diagram of cancellous bone in marrow is removed in the three-dimensional simulation of the utility model.
Fig. 2 b is that internal fixation device is implanted into bone grafting layer state schematic diagram by the three-dimensional simulation of the utility model.
Fig. 2 c is the installation condition schematic diagram that internal fixation device and bone grafting layer are connected and fixed by the three-dimensional simulation of the utility model.
Fig. 3 is a kind of individuation bone defect filling of the utility model structural schematic diagram of metal internal fixation device.
Fig. 4 is the art that bone grafting layer is implanted into using a kind of individuation bone defect filling metal internal fixation device of the utility model
Striograph afterwards.
Specific embodiment
The technical solution of the utility model is described further below in conjunction with drawings and examples.
Firstly, position and the size of preoperative imaging evaluation bone tumour.Art is carried out for the bone defect patient of different reasons
Preceding conventional image checks, including x-ray, CT(CT view are as shown in Figure 1a) and MRI(MRI view it is as shown in Figure 1 b) check, will
Related data typing computer simultaneously carries out software data processing, calculates range and the boundary of bone defect.Wherein, group CT high to density
It is clear to knit imaging, it is high for the distance between measurement bony structure accuracy.Multi-slices CT can be carried out three-dimensional imaging, facilitate
Stereoscopic display tissue and organ lesion.The soft tissue contrast resolution of MRI is high, can clearly differentiate muscle, tendon, fascia,
The soft tissues such as fat directly cut the ability of layer with any direction, cut layer in conjunction with different directions, can show examined device comprehensively
The structure of official or tissue, no observation dead angle, can directly make the body tomographic image on cross section, sagittal plane, coronal-plane and various inclined-planes,
Easily carry out the three-dimensional tracking of anatomical structure or lesion.
Then, based on Modern Imaging Technique and Computer-aided Design Technology to the bone defect area of specific needs reparation (i.e.
Lesions position) carry out three-dimensional reconstruction, obtain the parameters of internal fixation device implant, comprising shape, size, through-hole structure and
First through hole, the aperture of the second through-hole and third through-hole and porosity；Then it carries out three-dimensional simulation installation: first passing through three-dimensional simulation
Cancellous bone in the marrow of lesions position is removed, as shown in Figure 2 a, and simulates and moves into the internal fixation device of above-mentioned design, after perfect matching
(gap between internal fixation device and bone grafting layer is less than 5mm, i.e. gap between bone defect inner surface and internal fixation device outer surface),
Simulation is installed using cortex nail or spongiosa nail, as shown in Figure 2 c.
Finally, being prepared using the parameters of the internal fixation device of above-mentioned perfect simulation installation as foundation using 3D printing technique
The above-mentioned titanium alloy individuation internal fixation device for having both bone defect filling fixed support and Bone Ingrowth function.
As shown in figure 3, be a kind of metal internal fixation device prosthese provided by the utility model, it includes titanium alloy ontology 10,
It is provided with several first through hole (not shown) in the titanium alloy ontology, to carry out counterweight to internal fixation device, makes itself and defect portion
The intact bone weight (by scanning, measuring, simulation is calculated and obtained) of position is consistent.The titanium alloy ontology by 3D printing, with bone
Defect exact matching.The outer surface of the titanium alloy ontology be additionally provided with certain porosity (50-80%), aperture (400 μm-
800 μm, preferably 500-600 μm) the second through-hole 12, in order to Bone Ingrowth.The porosity, aperture are the needs according to Bone Ingrowth
Setting.The titanium alloy ontology is additionally provided with several third through-holes through ontology, is used for mounting screw, is fixed.It is described
Third through-hole include plain screw hole 131 and screw hole 132.Cortex nail or spongiosa nail, root may be selected in the screw
Depending on sclerotin according to bony site to be implanted.The screw can be plain screw or lock screw, and plain screw is corresponding common
Screw hole, lock screw correspond to screw hole.
Further, metal internal fixation device prosthese provided by the utility model can also carry out pre-formed Bone Ingrowth using preceding
Processing, processing method may is that the autologous stem cells of separation patient, by absorbing into the titanium prosthesis, pre- shape
At Bone Ingrowth.
In some embodiments, titanium prosthesis can also be immersed in the autologous stem cells liquid for being located away from patient, pre- shape
At Bone Ingrowth.
The metal internal fixation device application method of the utility model is as follows: according to the bone defect site morbidity situation of scanning, opening
Window removes cancellous bone in marrow, is implanted into the metal internal fixation device through above-mentioned Bone Ingrowth, is installing cortex spiral shell with cortex bone contact portion
Nail is installing spongiosa screw with cancellous bone contact portion, is being packed into lock screw in threaded mounting hole, so that metal internal fixation device and trouble
Person's autologous bone is closely connected and fixed, and postoperative image is as shown in Figure 4.
Through testing, after the metal internal fixation device installation of the utility model, user experience is very good, 28-42 days after installation, warp
Imageological examination can be observed Bone Ingrowth occur.
Due to the utility model metal internal fixation device prosthese can complete personalized customization, can be used not only for human body
The implantation of each position bone defect of whole body can be used for each position bone defect of whole body of other mammalian bodies in addition to human body
Implantation.
The internal fixation device of the utility model is implanted into body and realizes by designing with what bone defect regional morphology was identical
The support function of implants carries out metal implant surface porous to be designed to ensure that prosthese-bone interface Bone Ingrowth；Meanwhile
In order to reinforce the initial stability of implant, the design of fixing screws is added inside it.Moreover, in order to realize be implanted into device with
The adaptation of original diaphysis has also carried out counterweight processing, has not only improved user experience, moreover it is possible to so that internal fixation device and original diaphysis
Cooperate it is even closer, will not because dynamics difference due to it is unstable, greatly improve service life.The operation implantation 3D of the utility model is beaten
The implants of print, postoperative regular follow-up simultaneously carry out imaging evaluation, it was demonstrated that bone defect area filling is definite, and Bone Ingrowth is good.
It is discussed in detail although the content of the utility model has passed through above preferred embodiment, but it should be appreciated that on
The description stated is not considered as limitations of the present invention.After those skilled in the art have read above content, for
A variety of modifications and substitutions of the utility model all will be apparent.Therefore, the protection scope of the utility model should be by appended
Claim limit.
Claims (7)
1. a kind of individuation bone defect filling metal internal fixation device, which is characterized in that the internal fixation device is titanium prosthesis, should
Prosthese is internally provided with several first through hole, and outer surface is provided with several second through-holes, which also includes through prosthese
Third through-hole.
2. individuation bone defect filling metal internal fixation device as described in claim 1, which is characterized in that described first is logical
The porosity in hole and aperture are that computer is set according to the calculating of the density and volume of bone defect position diaphysis.
3. individuation bone defect filling metal internal fixation device as described in claim 1, which is characterized in that the titanium alloy
Prosthese is consistent with the diaphysis weight at position to be filled.
4. individuation bone defect filling metal internal fixation device as described in claim 1, which is characterized in that described second is logical
Hole is set according to the needs of Bone Ingrowth.
5. individuation bone defect filling metal internal fixation device as described in claim 1, which is characterized in that the hole of the second through-hole
Gap rate is 50-80%, and aperture is 400 μm -800 μm.
6. individuation bone defect filling metal internal fixation device as described in claim 1, which is characterized in that the third is logical
Hole is screw hole for attachment screw that prosthese and position to be filled is fixed.
7. individuation bone defect filling metal internal fixation device as claimed in claim 6, which is characterized in that the screw hole
Include plain screw hole and screw hole.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201820822944.0U CN208808624U (en) | 2018-05-30 | 2018-05-30 | A kind of individuation bone defect filling metal internal fixation device |
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| CN201820822944.0U CN208808624U (en) | 2018-05-30 | 2018-05-30 | A kind of individuation bone defect filling metal internal fixation device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108618837A (en) * | 2018-05-30 | 2018-10-09 | 上海交通大学医学院附属第九人民医院 | Individuation bone defect filling metal internal fixation device, preparation method and the usage |
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2018
- 2018-05-30 CN CN201820822944.0U patent/CN208808624U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108618837A (en) * | 2018-05-30 | 2018-10-09 | 上海交通大学医学院附属第九人民医院 | Individuation bone defect filling metal internal fixation device, preparation method and the usage |
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