CN208776747U - A kind of cell co-culture device - Google Patents
A kind of cell co-culture device Download PDFInfo
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- CN208776747U CN208776747U CN201821323277.8U CN201821323277U CN208776747U CN 208776747 U CN208776747 U CN 208776747U CN 201821323277 U CN201821323277 U CN 201821323277U CN 208776747 U CN208776747 U CN 208776747U
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- fixedly connected
- cabinet
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- 238000003501 co-culture Methods 0.000 title claims abstract description 27
- 230000000007 visual effect Effects 0.000 claims description 5
- 230000008878 coupling Effects 0.000 claims description 4
- 238000010168 coupling process Methods 0.000 claims description 4
- 238000005859 coupling reaction Methods 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 3
- 230000006978 adaptation Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 abstract description 13
- 238000002474 experimental method Methods 0.000 abstract description 8
- 238000012864 cross contamination Methods 0.000 abstract description 3
- 210000004027 cell Anatomy 0.000 description 28
- 238000000034 method Methods 0.000 description 6
- 238000004113 cell culture Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 210000004409 osteocyte Anatomy 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a kind of cell co-culture devices, including cabinet, transverse slat is fixedly connected between two sides at the top of the cabinet wall, and the surface of transverse slat slidably connects lantern ring, the bottom of the cabinet wall is fixedly connected with sliding rail, and the top slide of sliding rail is connected with slide plate, is fixedly connected to shell at the top of the bottom of collar face and slide plate, the utility model relates to co-culture device technical fields.The cell co-culture device, by being fixedly connected to shell at the top of the bottom of collar face and slide plate, so that after experiment, diaphragm can be disassembled and be cleaned, it is easy to operate, it is easy to use, conducive to continuing to use for experiment next time, intercellular cross contamination is not will cause, by being fixedly connected with tripod at the top of cabinet side, it is fixedly connected with motor at the top of tripod, can be adjusted according to quantity of the cell category to be cultivated to culturing room, use very convenient, reduction experimental cost.
Description
Technical field
The utility model relates to co-culture device technical field, specially a kind of cell co-culture device.
Background technique
It co-cultures, in order to establish the cultivating system for being more closely similar to vivo environment, makes vitro and vivo environment as far as possible
It matches, so that iuntercellular be enable to communicate with each other information, mutual support growing multiplication, people are on the basis of cell culture technology
Cell Co culturing Techenique is developed, Cell Co culturing Techenique is by two or more cell co-culture in same ring
In border, since it has the advantages that preferably to reflect vivo environment, it is widely used in INVENTIONModern cell research in this way
In, currently, Cell Co culturing Techenique is at most applied to osteocyte and nerve cell, cell co-culture system mainly passes through two kinds of sides
Method is established: Co-culture system and Indirect co-culture system.
Under aseptic condition in the experimentation for co-culturing cell, need to be total to two kinds and two or more cells
Culture, it is common by the iuntercellular factor realization through Mo Shiliangge culturing room, but two kinds of cells cannot pass through, at present mostly
Several cell co-culture device structures is single, inconvenient when experiment is finally cleaned, and the quantity of culturing room is solid
It is fixed, inconvenience is used, experimental cost is improved.
Utility model content
In view of the deficiencies of the prior art, the utility model provides a kind of cell co-culture device, and it is last to solve experiment
It is inconvenient when being cleaned, and the quantity of culturing room is fixed, the problem of using inconvenience, improve experimental cost.
In order to achieve the above object, the utility model is achieved by the following technical programs: a kind of cell co-culture device,
Including cabinet, transverse slat is fixedly connected between the two sides at the top of the cabinet wall, and the surface of transverse slat slidably connects lantern ring,
The bottom of the cabinet wall is fixedly connected with sliding rail, and the top slide of sliding rail is connected with slide plate, the bottom of the collar face
Shell is fixedly connected at the top of portion and slide plate, and the top and bottom of outer casing inner wall two sides slidably connects fixed block,
Electric telescopic rod, side of the fixed block far from outer casing inner wall are fixedly connected between the opposite side of two fixed blocks
It is rotatably connected to slide bar, and slide bar is rotatably connected to short slab far from one end of fixed block, side of the short slab far from slide bar is solid
Surely it is connected with fixed link, and fixed link is fixedly connected with riser far from one end of short slab, the surface of the fixed link and is located at perpendicular
Spring is arranged between the side of plate and the side of short slab, the side on the slide bar surface is rotatably connected to motion bar, and activity
The side of bar one end and riser far from slide bar is rotatablely connected.
Preferably, the riser is fixedly connected with fixture block, the opposite side of two shells far from the side of fixed link
Between be connected with diaphragm, the top and bottom of the diaphragm runs through shell and extends to the inside of shell.
Preferably, the diaphragm extends to the side of interior of shell and is flexibly connected with the side of outer casing inner wall, the diaphragm
Surface offer rectangular channel compatible with fixture block, be fixedly connected with tripod, and tripod at the top of the cabinet side
Top be fixedly connected with motor.
Preferably, one end of the motor output shaft is fixedly connected with threaded rod by shaft coupling, and the threaded rod is separate
One end of motor output shaft runs through cabinet and extends to the inside of cabinet, and the threaded rod extends to one end and the case of box house
The side rotation connection of internal wall.
Preferably, the two sides on the threaded rod surface are threaded with rectangular block, and are fixedly connected at the top of rectangular block
There are sliding block, the top slide connection of side and cabinet wall of the sliding block far from rectangular block, the bottom of the rectangular block and set
It is fixedly connected at the top of ring surface.
Preferably, the surface of the cabinet is connected with chamber door by screw thread, and the surface of the chamber door is fixedly connected with
Visual window.
Beneficial effect
The utility model provides a kind of cell co-culture device.Have compared with prior art it is following the utility model has the advantages that
(1), the cell co-culture device, by being fixedly connected to shell at the top of the bottom of collar face and slide plate,
And the top and bottom of outer casing inner wall two sides slidably connects fixed block, two fixed blocks are fixedly connected between opposite side
There is electric telescopic rod, fixed block is rotatably connected to slide bar far from the side of outer casing inner wall, and slide bar turns far from one end of fixed block
Dynamic to be connected with short slab, short slab is fixedly connected with fixed link, and the fixed company in the one end of fixed link far from short slab far from the side of slide bar
It is connected to riser, the surface of fixed link and is located between the side of riser and the side of short slab and is arranged with spring, the one of slide bar surface
Side is rotatably connected to motion bar, and the side rotation connection of motion bar one end and riser far from slide bar, and riser is far from fixed link
Side be fixedly connected with fixture block, two shells are connected with diaphragm between opposite side, and the top and bottom of diaphragm is equal
Through shell and the inside of shell is extended to, the surface of diaphragm offers rectangular channel compatible with fixture block, so that experiment terminates
Afterwards, diaphragm can be disassembled and is cleaned, it is easy to operate, it is easy to use, conducive to continuing to use for experiment next time, Bu Huizao
At intercellular cross contamination.
(2), cell co-culture device, by being fixedly connected with tripod, and the top of tripod at the top of cabinet side
Portion is fixedly connected with motor, and one end of motor output shaft is fixedly connected with threaded rod by shaft coupling, and threaded rod is defeated far from motor
One end of shaft is through cabinet and extends to the inside of cabinet, threaded rod extend to box house one end and cabinet wall one
Side rotation connection, the two sides on threaded rod surface are threaded with rectangular block, and sliding block is fixedly connected at the top of rectangular block, sliding
The top slide of side and cabinet wall of the block far from rectangular block connects, the fixed company in the bottom of rectangular block and the top of collar face
It connects, can be adjusted according to quantity of the cell category to be cultivated to culturing room, use is very convenient, reduces experimental cost.
Detailed description of the invention
Fig. 1 is the main view of the utility model structure；
Fig. 2 is the cross-sectional view of the utility model structure；
Fig. 3 is the cross-sectional view of the utility model shell mechanism.
In figure: 1 cabinet, 2 transverse slats, 3 lantern rings, 4 sliding rails, 5 slide plates, 6 shells, 7 fixed blocks, 8 electric telescopic rods, 9 slide bars, 10
Short slab, 11 fixed links, 12 risers, 13 springs, 14 motion bars, 15 fixture blocks, 16 diaphragms, 17 rectangular channels, 18 tripods, 19 motors,
20 threaded rods, 21 rectangular blocks, 22 sliding blocks, 23 chamber doors, 24 visual windows.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
Fig. 1-3 is please referred to, the utility model provides a kind of technical solution: a kind of cell co-culture device, including cabinet 1,
The surface of cabinet 1 is connected with chamber door 23 by screw thread, and the surrounding of chamber door 23 is provided with elastic tape, by screw chamber door 23
It is attached, better tightness, cell will not be polluted with cabinet 1,23 surface of chamber door is provided with to be adapted with culturing room
Round door, need the cell and culture solution cultivated for pouring into, the surface of chamber door 23 is fixedly connected with visual window 24, by can
The setting of form 24 is fixedly connected with transverse slat between the two sides at the top of 1 inner wall of cabinet convenient for the cellular activity in observation cabinet 1
2, and the surface of transverse slat 2 slidably connects lantern ring 3, the bottom of 1 inner wall of cabinet is fixedly connected with sliding rail 4, and the top of sliding rail 4 is sliding
Dynamic to be connected with slide plate 5, the bottom on 3 surface of lantern ring and the top of slide plate 5 are fixedly connected to shell 6, and 6 inner wall two sides of shell
Top and bottom slidably connects fixed block 7, and two fixed blocks 7 are fixedly connected with electric telescopic rod 8 between opposite side,
Electric telescopic rod 8 is controlled by external switch, and fixed block 7 is rotatably connected to slide bar 9 far from the side of 6 inner wall of shell, and
Slide bar 9 is rotatably connected to short slab 10 far from one end of fixed block 7, and short slab 10 is fixedly connected with fixed link far from the side of slide bar 9
11, and fixed link 11 is fixedly connected with riser 12 far from one end of short slab 10, side of the riser 12 far from fixed link 11 is fixed to be connected
It is connected to fixture block 15, diaphragm 16 is connected between the opposite side of two shells 6, diaphragm 16 is polycarbonate membrane, makes two
The iuntercellular factor of culturing room is realized common, but two kinds of cells cannot pass through, diaphragm 16 extend to side shell 6 inside and
The side of 6 inner wall of shell is flexibly connected, and the surface of diaphragm 16 offers rectangular channel 17 compatible with fixture block 15, by shell 6,
Fixed block 7, electric telescopic rod 8, slide bar 9, short slab 10, fixed link 11, riser 12, spring 13, motion bar 14, fixture block 15 and rectangle
The setting of slot 17, so that diaphragm 16 can be disassembled and be cleaned after experiment, it is easy to operate, it is easy to use, it is conducive to
Continuing to use for experiment next time, not will cause intercellular cross contamination, cabinet is fixedly connected with tripod at the top of 1 side
18, and the top of tripod 18 is fixedly connected with motor 19, one end of 19 output shaft of motor is fixedly connected with spiral shell by shaft coupling
Rasp bar 20, the two sides on 20 surface of threaded rod are threaded with rectangular block 21, and the top of rectangular block 21 is fixedly connected with sliding block
22, side of the sliding block 22 far from rectangular block 21 is connect with the top slide of 1 inner wall of cabinet, passes through motor 19, threaded rod 20, rectangle
The setting of block 21, sliding block 22, lantern ring 3, slide plate 5 and sliding rail 4, can according to the cell category to be cultivated to the quantity of culturing room and
Capacity is adjusted, and use is very convenient, reduces experimental cost, the fixed company in the bottom of rectangular block 21 and the top on 3 surface of lantern ring
It connects, threaded rod 20 runs through cabinet 1 far from one end of 10 output shaft of motor and extends to the inside of cabinet 1, and threaded rod 20 extends to
The side of one end and 1 inner wall of cabinet inside cabinet 1 is rotatablely connected, and the top and bottom of diaphragm 16 runs through shell 6 and extends
To the inside of shell 6, diaphragm 16 is provided with sealing ring through the junction of shell 6, enters in shell 6 to prevent culture solution, fixed
The surface of bar 11 and it is located between the side of riser 12 and the side of short slab 10 and is arranged with spring 13, the side on 9 surface of slide bar turns
It is dynamic to be connected with motion bar 14, and the one end of motion bar 14 far from slide bar 9 and the side of riser 12 are rotatablely connected.
The cell co-culture device of the utility model is aseptically to carry out cell culture, effectively increases cell
The survival rate and quality of culture.
In use, install diaphragm 16 according to the cell category to be cultivated, for the separation of culturing room, when installation, diaphragm
16 inject in shell 6, open electric telescopic rod 8, and fixed block 7 is driven to make a relative move, so that slide bar 9 and motion bar 14 carry out
Relative movement, fixed link 11 and riser 12 are close to diaphragm 16 so that fixture block 15 enter rectangular channel 17 in, to diaphragm 16 into
Row is fixed, and after being installed, opens motor 19, threaded rod 20 is driven to be rotated, so that sliding block 22 drives rectangular block 21
It is slided on threaded rod 20, lantern ring 3 is slided on transverse slat 2, so that shell 6 and diaphragm 16 are by slide plate 5 in sliding rail 4
On moved, it is identical to be adjusted to culture building volume, is then poured by the round door on chamber door 23 and needs the cell cultivated, logical
It crosses visual window 24 to be observed, this completes once to the use of the cell co-culture device.
It should be noted that, in this document, relational terms such as first and second and the like are used merely to a reality
Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation
In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to
Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those
Element, but also including other elements that are not explicitly listed, or further include for this process, method, article or equipment
Intrinsic element.
While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art,
It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired
Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.
Claims (6)
1. a kind of cell co-culture device, including cabinet (1), it is characterised in that: between the two sides at the top of cabinet (1) inner wall
It is fixedly connected with transverse slat (2), and the surface of transverse slat (2) slidably connects lantern ring (3), the bottom of cabinet (1) inner wall is fixed
It is connected with sliding rail (4), and the top slide of sliding rail (4) is connected with slide plate (5), the bottom and slide plate (5) on lantern ring (3) surface
Top be fixedly connected to shell (6), and the top and bottom of shell (6) inner wall two sides slidably connects fixed block (7),
Two fixed blocks (7) are fixedly connected with electric telescopic rod (8) between opposite side, and the fixed block (7) is far from shell
(6) side of inner wall is rotatably connected to slide bar (9), and slide bar (9) is rotatably connected to short slab far from the one end of fixed block (7)
(10), the short slab (10) is fixedly connected with fixed link (11) far from the side of slide bar (9), and fixed link (11) is far from short slab
(10) one end is fixedly connected with riser (12), the surface of the fixed link (11) and side and the short slab for being located at riser (12)
(10) it is arranged between side spring (13), the side on slide bar (9) surface is rotatably connected to motion bar (14), and activity
The side of bar (14) one end and riser (12) far from slide bar (9) is rotatablely connected.
2. a kind of cell co-culture device according to claim 1, it is characterised in that: the riser (12) is far from fixed link
(11) side is fixedly connected with fixture block (15), and two shells (6) are connected with diaphragm (16) between opposite side,
The top and bottom of the diaphragm (16) runs through shell (6) and extends to the inside of shell (6).
3. a kind of cell co-culture device according to claim 2, it is characterised in that: the diaphragm (16) extends to shell
(6) internal side is flexibly connected with the side of shell (6) inner wall, and the surface of the diaphragm (16) offers and fixture block (15) phase
The rectangular channel (17) of adaptation is fixedly connected with tripod (18) at the top of cabinet (1) side, and the top of tripod (18)
It is fixedly connected with motor (19).
4. a kind of cell co-culture device according to claim 3, it is characterised in that: the one of motor (19) output shaft
End is fixedly connected with threaded rod (20) by shaft coupling, and the threaded rod (20) runs through case far from one end of motor (10) output shaft
Body (1) and the inside for extending to cabinet (1), the threaded rod (20) extend to the internal one end of cabinet (1) and cabinet (1) inner wall
Side rotation connection.
5. a kind of cell co-culture device according to claim 4, it is characterised in that: the two of threaded rod (20) surface
Side is threaded with rectangular block (21), and sliding block (22) are fixedly connected at the top of rectangular block (21), and the sliding block (22) is remote
Side from rectangular block (21) is connect with the top slide of cabinet (1) inner wall, the bottom of the rectangular block (21) and lantern ring (3) table
It is fixedly connected at the top of face.
6. a kind of cell co-culture device according to claim 1, it is characterised in that: the surface of the cabinet (1) passes through
Screw thread is connected with chamber door (23), and the surface of the chamber door (23) is fixedly connected with visual window (24).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821323277.8U CN208776747U (en) | 2018-08-16 | 2018-08-16 | A kind of cell co-culture device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821323277.8U CN208776747U (en) | 2018-08-16 | 2018-08-16 | A kind of cell co-culture device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208776747U true CN208776747U (en) | 2019-04-23 |
Family
ID=66157386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821323277.8U Active CN208776747U (en) | 2018-08-16 | 2018-08-16 | A kind of cell co-culture device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208776747U (en) |
-
2018
- 2018-08-16 CN CN201821323277.8U patent/CN208776747U/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP02 | Change in the address of a patent holder |
Address after: 10/F, Block A, R&D Building, No. 666, Shendun 4th Road, Baoxie Street, Donghu New Technology Development Zone, Wuhan, Hubei Province, 430000 (Wuhan Area of Free Trade Zone) Patentee after: WUHAN HEYAN BIOMEDICAL TECHNOLOGY Co.,Ltd. Address before: Room b274-12, 2nd floor, building B1, biological innovation park, 666 Gaoxin Avenue, Donghu New Technology Development Zone, Wuhan City, Hubei Province, 430000 Patentee before: WUHAN HEYAN BIOMEDICAL TECHNOLOGY Co.,Ltd. |
|
| CP02 | Change in the address of a patent holder |