CN208742506U - A kind of charging device of aripiprazole drug substance intermediate - Google Patents

Abstract

The utility model discloses a kind of charging devices of aripiprazole drug substance intermediate, including feeding tank and reaction kettle, the feeding tank is fixed in the supporting table on the left of reaction kettle by stabilizer blade, the feeding tank is made of liquid case and solid-state case, and liquid case is located at the upper end of solid-state case, the right side lower end of the liquid case is connected with liquid conveying pipeline, the first solenoid valve is installed on the liquid conveying pipeline, it is connected with solid-state conveying pipeline on the right side of the lower end of the solid-state case, second solenoid valve is installed on the solid-state conveying pipeline.The utility model in feeding tank by being provided with solid-state case and liquid case, it connect liquid case and solid-state case with reaction kettle by liquid conveying pipeline and solid-state conveying pipeline, and the first solenoid valve and second solenoid valve are installed on liquid conveying pipeline and solid-state conveying pipeline, the speed to feed intake can be accurately controlled, it ensure that the efficiency of drug production, it is more practical, it is suitble to be widely popularized and uses.

Description

A kind of charging device of aripiprazole drug substance intermediate

Technical field

The utility model relates to pharmaceutical processing techniques field, the dress that feeds intake of specially a kind of aripiprazole drug substance intermediate It sets.

Background technique

Currently, Aripiprazole, for treating all types of schizophrenia, overseas clinical trial shows this product to spirit The positive and negative symptoms of Split disease have obvious curative effects, can also improve the affective symptom to occur together, reduce schizoid multiple Hair rate, and general pharmaceutical intermediate can use reaction kettle in process of production, mainly rely on and manually pass through scattered raw material The feed inlet of reaction kettle upper end is put into reaction kettle, more time-consuming in this way, and the speed not easy to control to feed intake.Therefore, It is proposed that a kind of charging device of aripiprazole drug substance intermediate.

Utility model content

The purpose of this utility model is to provide a kind of charging devices of aripiprazole drug substance intermediate, by feeding tank It is inside provided with solid-state case and liquid case, liquid case and solid-state case is then made to pass through liquid conveying pipeline and solid-state conveying pipeline and reaction kettle Connection, and the first solenoid valve and second solenoid valve are installed on liquid conveying pipeline and solid-state conveying pipeline, it can be accurately controlled The speed to feed intake ensure that the efficiency of drug production, more practical, is suitble to be widely popularized and use, solves in background technique The problem of proposed.

To achieve the above object, the utility model provides the following technical solutions: a kind of throwing of aripiprazole drug substance intermediate Expect that device, including feeding tank and reaction kettle, the feeding tank are fixed in the supporting table on the left of reaction kettle by stabilizer blade, the throwing Hopper is made of liquid case and solid-state case, and liquid case is located at the upper end of solid-state case, and the right side lower end of the liquid case is connected with Liquid conveying pipeline, the first solenoid valve is equipped on the liquid conveying pipeline, and it is defeated to be connected with solid-state on the right side of the lower end of the solid-state case Expects pipe, is equipped with second solenoid valve on the solid-state conveying pipeline, the liquid conveying pipeline and solid-state conveying pipeline with reaction kettle Upper end connection.

As a kind of preferred embodiment of the utility model, the first observation window and are provided in the middle part of the feeding tank Two observation windows, first observation window are located at the outside of solid-state case, and second observation window is located at the outside of liquid case.

As a kind of preferred embodiment of the utility model, drive is fixed on the box outer wall that feeds intake on the left of the solid-state case Motor is moved, helical blade is installed in the shaft of the driving motor, the helical blade is located inside solid-state case, and drives electricity Machine and external device are electrically connected.

As a kind of preferred embodiment of the utility model, the upper end two sides of the feeding tank be connected separately with solid-state into Material mouth and liquid feed mouth, the solid feedstock mouth are connected to solid-state case, and the liquid feed mouth is connected to liquid case.

As a kind of preferred embodiment of the utility model, first solenoid valve and second solenoid valve are set with the external world It is standby to be electrically connected.

Compared with prior art, the beneficial effects of the utility model are as follows:

1. the charging device of the aripiprazole drug substance intermediate of the utility model, is provided with solid-state case and liquid in feeding tank State case connect liquid case and solid-state case with reaction kettle by liquid conveying pipeline and solid-state conveying pipeline, and in liquid conveying The first solenoid valve and second solenoid valve are installed on pipe and solid-state conveying pipeline, the speed to feed intake can be accurately controlled, ensure that The efficiency of drug production.

2. the charging device of the aripiprazole drug substance intermediate of the utility model is provided with the first sight on the surface of feeding tank Window and the second observation window are examined, raw material inside solid-state case and liquid case can be understood through the first observation window and the second observation window constantly It is the case where surplus, convenient to make adjustment in time.

3. the charging device of the aripiprazole drug substance intermediate of the utility model is internally provided with helical-blade in solid-state case Piece, and it is mounted on it in shaft of driving motor, enable helical blade that solid-state drug is quickly transmitted to solid-state conveying At pipe, drug is prevented all to be deposited in the left side of solid-state case.

Detailed description of the invention

Upon reading the detailed description of non-limiting embodiments with reference to the following drawings, other spies of the utility model Sign, objects and advantages will become more apparent upon:

Fig. 1 is the overall structure diagram of the charging device of the utility model aripiprazole drug substance intermediate；

Fig. 2 is the feeding tank structural schematic diagram of the charging device of the utility model aripiprazole drug substance intermediate.

In figure: 1, feeding tank；2, reaction kettle；3, solid feedstock mouth；4, driving motor；5, the first observation window；6, stabilizer blade；7, Supporting table；8, liquid feed mouth；9, the second observation window；10, liquid conveying pipeline；11, solid-state conveying pipeline；12, liquid case；13, solid State case；14, helical blade；15, the first solenoid valve；16, second solenoid valve.

Specific embodiment

To be easy to understand the technical means, creative features, achievement of purpose, and effectiveness of the utility model, below In conjunction with specific embodiment, the utility model is further described.

The utility model provides a kind of technical solution referring to FIG. 1-2: a kind of dress that feeds intake of aripiprazole drug substance intermediate It sets, including feeding tank 1 and reaction kettle 2, the feeding tank 1 is fixed in the supporting table 7 in 2 left side of reaction kettle by stabilizer blade 6, described Feeding tank 1 is made of liquid case 12 and solid-state case 13, and liquid case 12 is located at the upper end of solid-state case 13, the right side of the liquid case 12 Side lower end is connected with liquid conveying pipeline 10, and the first solenoid valve 15 is equipped on the liquid conveying pipeline 10, the solid-state case 13 It is connected with solid-state conveying pipeline 11 on the right side of lower end, second solenoid valve 16, the liquid conveying are installed on the solid-state conveying pipeline 11 Pipe 10 and solid-state conveying pipeline 11 are connected to the upper end of reaction kettle 2.

(Fig. 1 and Fig. 2 are please referred to) by being provided with solid-state case 13 and liquid case 12 in feeding tank 1, so in the present embodiment After connect liquid case 12 and solid-state case 13 with reaction kettle 2 by liquid conveying pipeline 10 and solid-state conveying pipeline 11, and it is defeated in liquid First solenoid valve 15 and second solenoid valve 16 are installed in expects pipe 10 and solid-state conveying pipeline 11, the speed to feed intake can be accurately controlled Degree ensure that the efficiency of drug production.

Wherein, the middle part of the feeding tank 1 is provided with the first observation window 5 and the second observation window 9, first observation window 5 Positioned at the outside of solid-state case 13, second observation window 9 is located at the outside of liquid case 12.

(Fig. 1 and Fig. 2 are please referred to) in the present embodiment by being provided with the first observation window 5 and second on the surface of feeding tank 1 Observation window 9 can penetrate constantly the first observation window 5 and the second observation window 9 understands more than solid-state case 13 and 12 inside raw material of liquid case It is the case where amount, convenient to make adjustment in time.

Wherein, it is fixed with driving motor 4 on 1 outer wall of feeding tank in 13 left side of solid-state case, the driving motor 4 turns Helical blade 14 is installed, the helical blade 14 is located inside solid-state case 13, and driving motor 4 and external device are electrical on axis Connection.

(Fig. 2 is please referred to) in the present embodiment by being internally provided with helical blade 14 in solid-state case 13, and makes its installation In the shaft of driving motor 4, enables helical blade 14 that quickly solid-state drug to be transmitted at solid-state conveying pipeline 11, prevent Drug is all deposited in the left side of solid-state case 13.

Wherein, the upper end two sides of the feeding tank 1 are connected separately with solid feedstock mouth 3 and liquid feed mouth 8, the solid-state Feed inlet 3 is connected to solid-state case 13, and the liquid feed mouth 8 is connected to liquid case 12.

Wherein, first solenoid valve 15 and second solenoid valve 16 are electrically connected with external device.

When a kind of charging device of aripiprazole drug substance intermediate uses, by solid feedstock mouth 3 and liquid feed Mouth 8 is connect with feed pipe, makes in solid-state case 13 and liquid case 12 is interior by injection solid-state drug and liquid drug, set by the external world Standby first solenoid valve 15 of opening can be such that the drug in liquid case 12 enters in reaction kettle 2 by liquid conveying pipeline 10, pass through External device opens second solenoid valve 16 and driving motor 4, makes helical blade 14 that solid-state drug be driven to be sent to solid-state conveying pipeline 11, then into reaction kettle 2, realize the purpose for being accurately controlled the speed to feed intake.

The basic principles and main features of the present invention and the advantages of the present invention have been shown and described above, for For those skilled in the art, it is clear that the present invention is not limited to the details of the above exemplary embodiments, and without departing substantially from this In the case where the spirit or essential attributes of utility model, the utility model can be realized in other specific forms.Therefore, no matter From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the utility model is by institute Attached claim rather than above description limit, it is intended that will fall within the meaning and scope of the equivalent elements of the claims All changes are embraced therein.It should not treat any reference in the claims as limiting related right It is required that.

In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art The other embodiments being understood that.

Claims (5)

1. a kind of charging device of aripiprazole drug substance intermediate, including feeding tank (1) and reaction kettle (2), it is characterised in that: institute It states feeding tank (1) to pass through in the supporting table (7) that stabilizer blade (6) are fixed on the left of reaction kettle (2), the feeding tank (1) is by liquid case (12) it is formed with solid-state case (13), and liquid case (12) is located at the upper end of solid-state case (13), under the right side of the liquid case (12) End is connected with liquid conveying pipeline (10), is equipped with the first solenoid valve (15) on the liquid conveying pipeline (10), the solid-state case (13) it is connected with solid-state conveying pipeline (11) on the right side of lower end, second solenoid valve (16) is installed on the solid-state conveying pipeline (11), The liquid conveying pipeline (10) and solid-state conveying pipeline (11) are connected to the upper end of reaction kettle (2).

2. a kind of charging device of aripiprazole drug substance intermediate according to claim 1, it is characterised in that: described to feed intake The first observation window (5) and the second observation window (9) are provided in the middle part of case (1), first observation window (5) is located at solid-state case (13) Outside, second observation window (9) is located at the outside of liquid case (12).

3. a kind of charging device of aripiprazole drug substance intermediate according to claim 1, it is characterised in that: the solid-state It is fixed with driving motor (4) on feeding tank (1) outer wall on the left of case (13), spiral shell is installed in the shaft of the driving motor (4) Vane piece (14), it is internal that the helical blade (14) is located at solid-state case (13), and driving motor (4) electrically connects with external device It connects.

4. a kind of charging device of aripiprazole drug substance intermediate according to claim 1, it is characterised in that: described to feed intake The upper end two sides of case (1) are connected separately with solid feedstock mouth (3) and liquid feed mouth (8), the solid feedstock mouth (3) and solid-state Case (13) connection, the liquid feed mouth (8) are connected to liquid case (12).

5. a kind of charging device of aripiprazole drug substance intermediate according to claim 1, it is characterised in that: described first Solenoid valve (15) and second solenoid valve (16) are electrically connected with external device.