CN208732985U - A kind of rapid Solid-phase synthesis peptides mechanism of temperature adjustment - Google Patents
A kind of rapid Solid-phase synthesis peptides mechanism of temperature adjustment Download PDFInfo
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- CN208732985U CN208732985U CN201821177362.8U CN201821177362U CN208732985U CN 208732985 U CN208732985 U CN 208732985U CN 201821177362 U CN201821177362 U CN 201821177362U CN 208732985 U CN208732985 U CN 208732985U
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- fixed strip
- phase synthesis
- synthesis peptides
- fixedly connected
- placing groove
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Abstract
The utility model discloses a kind of rapid Solid-phase synthesis peptides mechanisms of temperature adjustment, including Solid-phase synthesis peptides instrument, multiple placing grooves are provided on Solid-phase synthesis peptides instrument, bottom is fixedly connected with multiple elastic components in placing groove, the upper end of elastic component is fixedly connected with retainer plate, it is fixedly connected with rubber column on retainer plate, reaction flask is placed on retainer plate, the upper end of reaction flask is plugged with siphunculus；The device is by being arranged multiple placing grooves; and it is provided with elastic component and rubber column in placing groove and plays preliminary protection to reaction utensil; fixed strip is correspondingly arranged on the outside of placing groove; further stabilization is played to the upper end of reaction utensil; and fixed strip has a certain range of adjustment effect; it can be fixed for different size of reaction utensil, the apparatus structure simple operations are convenient, have very high practical value.
Description
Technical field
The utility model relates to the correlative technology field of Solid-phase synthesis peptides, specially a kind of rapid Solid-phase Polypeptide of temperature adjustment
Combination mechanism.
Background technique
The chemical synthesising technology of polypeptide either liquid phase method or solid phase method are all mature, and in recent decades, solid phase method is more
Method of peptide synthesis is time saving with its, laborsaving, material-saving, convenient for automatically controlling, outstanding advantage easy to popularize and become Peptide systhesis
Conventional method, and expand to nucleic acid synthesis etc. other fields, developed successfully solid-phase polypeptide conjunction from Merrifield in 1963
Since at method, by continuous improve and perfect, one had become in peptide and protein synthesis to solid phase method today is normal
With technology, and promote the Fully automated synthesis of polypeptide
In the prior art, Solid-phase synthesis peptides instrument is all for multichannel, and reaction kit is mostly glass wares, but existing anti-
Glass wares is answered mostly simply to be placed in Solid-phase synthesis peptides instrument, there is no any safeguard measures, and glass wares is easy
It breaks into pieces and causes damages；For this purpose, the utility model proposes a kind of rapid Solid-phase synthesis peptides mechanisms of temperature adjustment for solving above-mentioned ask
Topic.
Utility model content
The purpose of this utility model is to provide a kind of rapid Solid-phase synthesis peptides mechanisms of temperature adjustment, to solve above-mentioned background
The problem of being proposed in technology.
To achieve the above object, the utility model provides the following technical solutions: a kind of rapid Solid-phase synthesis peptides of temperature adjustment
Mechanism, including Solid-phase synthesis peptides instrument are provided with multiple placing grooves, bottom in the placing groove on the Solid-phase synthesis peptides instrument
Multiple elastic components are fixedly connected with, the upper end of the elastic component is fixedly connected with retainer plate, is fixedly connected with rubber on the retainer plate
Rubber column gel column is placed with reaction flask on the retainer plate, and the upper end of the reaction flask is plugged with siphunculus, and the siphunculus is set through rodding eye
It sets, the upper end of the placing groove is fixedly installed fixed link, left fixed strip and right fixed strip are fixedly connected in the fixed link,
The both ends of the left fixed strip and right fixed strip are fixedly connected with limit plate, and through-hole, spiral shell on through-hole are offered on the limit plate
It is connected to limited post, is bolted with fixture nut on the limited post.
Preferably, the placing groove is provided with multiple, and the section of multiple placing grooves is circular configuration, multiple placing grooves
Area of section size is different from volume.
Preferably, the elastic component is arc-shaped, and the elastic component is provided with multiple, and the arc of multiple elastic components is inside
Bending, the bottom ends uniform in size for being arranged in placing groove such as multiple elastic components are equidistant.
Preferably, the rubber column is provided at least two, and two rubber columns are symmetricly set on the upper end of retainer plate, rubber
Column is in inverted l-shaped structure, and the height of rubber column is less than the depth of placing groove, and the crossbeam of rubber column is less than the half of retainer plate inner circular
Diameter.
Preferably, the right fixed strip is arcuate structure, and the top and bottom of right fixed strip are fixedly connected with limit plate,
The limit plate is rectangular plate-like structure, and the centre of limit plate offers circular through hole, is provided with internal screw thread in circular through hole,
The left fixed strip is the structure symmetrical with right fixed strip, and the size shape of left fixed strip and right fixed strip size shape are homogeneous
Together.
Compared with prior art, the utility model has the beneficial effects that
The device is provided with elastic component and rubber column plays reaction utensil by the way that multiple placing grooves are arranged in placing groove
Preliminary protection, placing groove outside are correspondingly arranged on fixed strip, play further stabilization to the upper end of reaction utensil, and
Fixed strip has a certain range of adjustment effect, can be fixed for different size of reaction utensil, apparatus structure letter
Single operation is convenient, has very high practical value.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model；
Fig. 2 is the reaction flask and Solid-phase synthesis peptides instrument structural blast schematic diagram of the utility model；
Fig. 3 is the fixed rod structure top view of the utility model.
In figure: 1 Solid-phase synthesis peptides instrument, 2 placing grooves, 3 fixed links, 4 rodding eyes, 5 elastic components, 6 retainer plates, 7 rubber columns,
8 reaction flasks, 9 siphunculus, 10 left fixed strips, 11 right fixed strips, 12 limit plates, 13 limited posts, 14 fixture nuts.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
Fig. 1-3 is please referred to, the utility model provides a kind of technical solution: a kind of rapid Solid-phase synthesis peptides machine of temperature adjustment
Structure, including Solid-phase synthesis peptides instrument 1 are provided with multiple placing grooves 2 on Solid-phase synthesis peptides instrument 1, and bottom is fixed in placing groove 2 connects
Multiple elastic components 5 are connected to, the upper end of elastic component 5 is fixedly connected with retainer plate 6, and rubber column 7 is fixedly connected on retainer plate 6, fixed
Be placed with reaction flask 8 on circle 6, the upper end of reaction flask 8 is plugged with siphunculus 9, siphunculus 9 through the setting of rodding eye 4, placing groove 2 it is upper
End is fixedly installed fixed link 3, and left fixed strip 10 and right fixed strip 11, left fixed strip 10 and the right side are fixedly connected in fixed link 3
The both ends of fixed strip 11 are fixedly connected with limit plate 12, and through-hole is offered on limit plate 12, and limited post 13 is bolted on through-hole, limit
Fixture nut 14 is bolted on the column 13 of position.
Further, placing groove 2 is provided with multiple, and the section of multiple placing grooves 2 is circular configuration, multiple placing grooves 2
Area of section size it is different from volume, volume reaction flask 8 of different sizes is placed in placing groove 2.
Further, elastic component 5 be it is arc-shaped, elastic component 5 be provided with it is multiple, the arc of multiple elastic components 5 inwardly it is curved
Song, the bottom end uniform in size for being arranged in placing groove 2, the elastic components 5 such as multiple elastic components 5 are equidistant play certain buffer function.
Further, rubber column 7 is provided at least two, and two rubber columns 7 are symmetricly set on the upper end of retainer plate 6, rubber
Rubber column gel column 7 is in inverted l-shaped structure, and the height of rubber column 7 is less than the depth of placing groove 2, and the crossbeam of rubber column 7 is less than 6 inner circle of retainer plate
The radius of shape, rubber column 7 play certain squeezing action to the lower end side of reaction flask 8.
Further, right fixed strip 11 is arcuate structure, and the top and bottom of right fixed strip 11 are fixedly connected with limit
Plate 12, limit plate 12 are rectangular plate-like structure, and the centre of limit plate 12 offers circular through hole, are provided in circular through hole interior
Screw thread, left fixed strip 10 are the structure symmetrical with right fixed strip 11, and the size shape of left fixed strip 10 and right fixed strip 11 are big
Small shape is all the same, and left fixed strip 10 and right fixed strip 11 play stable effect to the upper end of reaction flask 8.
Working principle: in actual work, reaction flask 8 of different sizes is placed in corresponding placing groove 2, placing groove 2
The rubber column 7 of bottom end plays fixed function to the side of reaction flask 8, and the bottom end of reaction flask 8 is placed in the inner ring of retainer plate 6
End, the elastic component 5 of 6 lower end of retainer plate play certain buffer function to reaction flask 8 under external force, then will be in fixed link 3
Left fixed strip 10 and right fixed strip 11 upper end of reaction flask 8 is socketed, according to the big minor adjustment fixture nut of reaction flask 8
14 position on limited post 13, until the inner ring of left fixed strip 10 and right fixed strip 11 have to the upper end of reaction flask 8 it is certain
Lateral pressure effect, finally passes through rodding eye 4 for siphunculus 9, keeps whole device more stable.
While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art,
It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired
Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.
Claims (5)
1. a kind of rapid Solid-phase synthesis peptides mechanism of temperature adjustment, including Solid-phase synthesis peptides instrument (1), it is characterised in that: described more
It is provided on peptide solid phase synthetic instrument (1) multiple placing grooves (2), the interior bottom of the placing groove (2) is fixedly connected with multiple elastic components
(5), the upper end of the elastic component (5) is fixedly connected retainer plate (6), is fixedly connected with rubber column (7) on the retainer plate (6),
It is placed with reaction flask (8) on the retainer plate (6), the upper end of the reaction flask (8) is plugged with siphunculus (9), and the siphunculus (9) is passed through
Break-through pore (4) setting, the upper end of the placing groove (2) are fixedly installed fixed link (3), fixed on the fixed link (3) to connect
It is connected to left fixed strip (10) and right fixed strip (11), the both ends of the left fixed strip (10) and right fixed strip (11) are fixedly connected with
Limit plate (12) offers through-hole on the limit plate (12), is bolted on through-hole limited post (13), on the limited post (13)
It is bolted with fixture nut (14).
2. the rapid Solid-phase synthesis peptides mechanism of a kind of temperature adjustment according to claim 1, it is characterised in that: the placing groove
(2) it is provided with multiple, the section of multiple placing grooves (2) is circular configuration, the area of section size and body of multiple placing grooves (2)
Product is different.
3. the rapid Solid-phase synthesis peptides mechanism of a kind of temperature adjustment according to claim 1, it is characterised in that: the elastic component
(5) to be arc-shaped, the elastic component (5) is provided with multiple, and the arc of multiple elastic components (5) curves inwardly, multiple elastic components
(5) bottom end uniform in size for being arranged in placing groove (2) such as equidistant.
4. the rapid Solid-phase synthesis peptides mechanism of a kind of temperature adjustment according to claim 1, it is characterised in that: the rubber column
(7) at least two are provided with, two rubber columns (7) are symmetricly set on the upper end of retainer plate (6), and rubber column (7) is in inverted L-shaped knot
Structure, the height of rubber column (7) are less than the depth of placing groove (2), and the crossbeam of rubber column (7) is less than the half of retainer plate (6) inner circular
Diameter.
5. the rapid Solid-phase synthesis peptides mechanism of a kind of temperature adjustment according to claim 1, it is characterised in that: the right fixation
Item (11) is arcuate structure, and the top and bottom of right fixed strip (11) are fixedly connected with limit plate (12), the limit plate
It (12) is rectangular plate-like structure, the centre of limit plate (12) offers circular through hole, internal screw thread, institute are provided in circular through hole
Stating left fixed strip (10) is the structure symmetrical with right fixed strip (11), the size shape of left fixed strip (10) and right fixed strip
(11) size shape is all the same.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821177362.8U CN208732985U (en) | 2018-07-24 | 2018-07-24 | A kind of rapid Solid-phase synthesis peptides mechanism of temperature adjustment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821177362.8U CN208732985U (en) | 2018-07-24 | 2018-07-24 | A kind of rapid Solid-phase synthesis peptides mechanism of temperature adjustment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208732985U true CN208732985U (en) | 2019-04-12 |
Family
ID=66026852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821177362.8U Active CN208732985U (en) | 2018-07-24 | 2018-07-24 | A kind of rapid Solid-phase synthesis peptides mechanism of temperature adjustment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208732985U (en) |
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2018
- 2018-07-24 CN CN201821177362.8U patent/CN208732985U/en active Active
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