CN208659362U - A kind of portable visual electrophysiology detection system - Google Patents
A kind of portable visual electrophysiology detection system Download PDFInfo
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- CN208659362U CN208659362U CN201721823020.4U CN201721823020U CN208659362U CN 208659362 U CN208659362 U CN 208659362U CN 201721823020 U CN201721823020 U CN 201721823020U CN 208659362 U CN208659362 U CN 208659362U
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Abstract
The utility model provides a kind of portable visual electrophysiology detection system, including helmet, the helmet is used for holding movable equipment, detecting electrode, signal amplifier, the helmet also includes multi-channel structure, and the signal of each detecting electrode is by again being exported the signal collection of each detecting electrode to mobile device by multi-channel structure after signal amplifier.Short connecting line between the sensor and amplifier of the utility model, most external noise and interference will be eliminated, the design makes signal signal-to-noise ratio with higher, higher reproducibility, higher common-mode rejection ratio and improves the sensibility to lower stimulation, disposable electrode can be made in electrode, it prevents from infecting, beneficial to patient and doctor, and meet hospital infection control standard.
Description
[technical field]
The utility model relates to ophthalmic medical technical fields, are specifically related to a kind of portable visual electrophysiology detection system
System.
[background technique]
Visual electrophysiology detection is that a kind of record is released under light or Form Vision stimulation from eyes, optic nerve or brain
The technology that electric discharge position changes.The function of energy objective measurement retina, optic nerve and pathways for vision.
Visual electrophysiology detection specifically includes that
1. electroretinogram (ERG)
The main retina of electroretinogram (ERG) reflects photosensory cell to Beale's ganglion cells and the function of amakrine.Depending on
Nethike embrane current graph is clinically usually used in hereditary retinal dystrophy (such as retinal pigment degeneration), diabetic retinopathy
Change, detachment of retina, eye traumas (such as siderosis retinae disease and sympathetic ophthalmia), the diagnosis of the diseases such as colour blindness.
2. electric eye figure (EOG)
Electroculogram (EOG) is measurement existing retina electrostatic between retinal pigment epithelium and photoreceptor cell
Position.According to the variation of retina rest potential under the conditions of light and dark adaptation, can reflect photoreceptor cell photochemical reaction and
The function status of ectoretina, it can also be used to measure eyeball position and oculomotor physiological change.
3. visual evoked potential (VEP)
Functional status of visual evoked potential (VEP) retinal ganglion cells to visual cortex.Its check purpose be to
Speculate from retina to the health status of Conductive fiber cerebral cortex and optic cortex functional activity situation.Work as visual loss
When the EOG and ERG of patient checks normal, then lesion is more than gangliocyte between cerebral cortex.
4. multiple-focus electroretinogram (MfERG)
Multiple-focus electroretinogram (MfERG) system allows to assess electroretinogram activity in the zonule of retina.Pass through
This method can record multiple-focus electroretinogram from hundreds of retinal areas in several minutes.
Visual electrophysiology detection clinically provides eye disease diagnosis, excludes to regard during specified conditions, prognosis and treatment
Feel functional assessment etc., also plays an important role to patient in the eye disease diagnosis of early stage.Detecting instrument is generally by three main portions
It is grouped as, comprising: the record and processing unit of detecting electrode, light or pictorial stimulus device and data.
The electrode of visual electrophysiology detection is all commercially available, but most of is all Passive electrode, is not included any active
Electronic component.It is well known that Passive electrode has the problem of low interference resistance.Therefore, in visual electrophysiology detection, ring is come from
The electromagnetic noise in border would generally interference signal.The noise of 50Hz/60Hz be it is particularly common, it is referred to as line noise because
It is issued by feed cable.Therefore, the quality of visual electrophysiology detection signal is affected, to reduce theirs
Diagnosis capability.The visual electrophysiology detecting electrode of most of commercial has very long transmission electric wire, this is conveniently docked with farther away
On device, but electrode is made to be easier the interference made an uproar by electromagnetism.For Passive electrode, convenient between record quality
Always exist choice.Also because active electrode is easy the interference made an uproar by electromagnetism.Deviation is easy to appear in analysis and influences standard
Really judgement.
On the other hand, the instrument prices of all examination of visual electro physiology is generally integrated costly, and volume is all larger,
Electrode detection, which can be combined, without one kind and is worn on integrated product occurs.And in some cases, such as in the bed of hospital
In side or therapeutic room, for patient because inconvenience is mobile, posture may be to be seated, and inclination or recumbency, at this moment we need one kind can
The device detected is done in face of patient to be easy to be placed on, so the mobility of visual electrophysiology detector is considerable.And
When darkroom is observed, needs to special darkroom Fang Licai to be able to achieve, waste biggish space.As intelligent portable objects technology becomes
It is mature and universal, intelligent portable objects now can be operated easily and relatively cheap.We are directed to intelligent portable objects
Availability technology, so that intelligent portable objects is extended to clinical ophthalmology visual electrophysiology detection device.Us are cooperated to develop
The compatible active electrode in intelligent portable objects becomes and uses except generally detection environment and world remote districts
Ideal chose.
[summary of the invention]
The utility model solves that existing visual electrophysiology detection device volume is big, inconvenient to use, accuracy is low asks
Topic provides a kind of portable visual electrophysiology detection system.
A kind of detection system of portable visual electrophysiology of the utility model adopts the technical scheme that
A kind of portable visual electrophysiology detection system, including helmet, the helmet are set for holding movable
Standby, detecting electrode, signal amplifier, the helmet also include multi-channel structure, and the signal of each detecting electrode passes through signal
The signal collection of each detecting electrode is exported to mobile device by multi-channel structure again after amplifier.
Preferably, the detecting electrode is ERG electrode, EOG electrode and VEP electrode.
Preferably, the signal amplifier is that signal preamplifier and VEP signal amplifier, signal preamplifier have
Adjustable gain knob has adjustable gain knob for amplifying for amplifying ERG electrode and EOG electrode signal, VEP signal amplifier
The signal of VEP electrode；The signal of detection connects mobile device by independent channel after multi-channel structure conversion.
Preferably, there is a LCD display on signal preamplifier, be used for real-time read test data.
Preferably, signal amplifier is additionally provided with independent battery module.
Preferably, the signal preamplifier also includes ground electrode and reference electrode, and the ERG electrode and EOG are electric
Extremely share a ground electrode and reference electrode.
Preferably, there are three types for ERG electrode, are Corneal Contact type, conjunctiva contact-type and skin contact type respectively.
Preferably, ERG electrode, EOG electrode, VEP electrode, ground electrode and reference electrode by magnetic part removably with
Respective signal amplifier is connected.
Preferably, the magnetic part connecting portion is gold-plated or plates silver chlorate.
Preferably, the mobile device is equipped with display screen, processor, software module and stimulating module, i.e. mobile device
Integrated data processing, display, stimulatory function, and the electric signal that can also be will test is converted to graphical display.
Preferably, the software module control display screen is stimulated, and the standard that the display screen is world ISCEV uses
OLED display screen.
Preferably, the helmet has 5 VEP slot electrodes on rack there are also VEP electrode rack, is in cross
Type distribution, for placing VEP electrode.
Preferably, helmet is equipped with the loosing and tightening structure for holding movable equipment.
Preferably, helmet is capable of forming darkroom, i.e., sees that movement is set by eyes after putting mobile device wearing
The standby space that is formed by is darkroom, not light leakage.
Preferably, the helmet also includes two power lens, and eyes need to see that movement is set by power lens
Standby screen.
A kind of portable visual electrophysiology detection system provided by the utility model is shared by ERG electrode and EOG electrode
One reference electrode and ground electrode, can be achieved at the same time retinal cell function of eyes inspection and retinal pigment epithelium and photoreceptor
Complex functional check.In addition, VEP electrode can be realized the inspection of pathways for vision situation.
It realizes that preamplifier is affixed on face by reference to electrode by helmet, as close to signal source, reduces
The mode of conductor length eliminates the noise from cable conductor, and solving current conventional detection devices, signal is micro- in use
It is weak, interference it is more the problems such as, by be arranged battery module, active electrode is more resistant to electronic interferences, because it is exaggerated source
Signal.
Helmet can form darkroom with mobile device, reach the condition of detection, helmet is lightweight and convenient, volume
It is small, it is convenient for carrying, the data of detection directly connect data processing display device by conducting wire, can obtain testing result in real time.
[Detailed description of the invention]
Fig. 1 is the portable visual electrophysiology detection system wearing schematic of the utility model；
Fig. 2 is the portable visual electrophysiology detection system perspective view of the utility model；
Fig. 3 is the portable visual electrophysiology detection system helmet of the utility model and mobile device schematic diagram；
Fig. 4 is the portable visual electrophysiology detection system wearing schematic of the utility model；
Fig. 5 is the utility model VEP electrode and VEP electrode rack structure chart.
Fig. 6 is the utility model ERG electrode and EOG electrode inspector structure chart.
Fig. 7 is the utility model ERG electrode conjunctiva contact-type and skin contact type structural schematic diagram.
Fig. 8 is the utility model ERG electrode conjunctiva contact-type and skin contact type wearing schematic.
Fig. 9 is the utility model ERG electrode and EOG electrode signal preamplifier circuit diagram；
Figure 10 is the ERG electrode of the utility model and the ERG electricity that tradition ERG electrode compares in the same detection time
Figure；
Figure 11 is that the ERG electrode ERG electrograph that repeated detection obtains in the same detection time of the utility model repeats
Degree is more preferable；
Figure 12 is the EOG waveform electrode figure of the utility model；
Figure 13 is the VEP waveform electrode figure of the utility model；
It wherein, 1 is helmet in figure, 101 be loosing and tightening structure, and 102 be multi-channel structure, and 103 be darkroom, and 104 be coke
Eyeglass is spent, 2 be mobile device, and 3 be VEP electrode rack, and 31 be VEP slot electrode, and 4 be VEP electrode, the first VEP electrode 401,
2nd VEP electrode 402, the 3rd VEP electrode 403, the 4th VEP electrode 404, the 5th VEP electrode 405,41 amplify for VEP signal
Device, 42 be adjustable gain knob, and 5 be signal preamplifier, and 51 be LCD display, and 53 be adjustable gain knob, and 6 be reference
Electrode, 7 be ground electrode, and 8 be EOG electrode, and 9 be ERG electrode/Corneal Contact type ERG electrode, and 91 be conjunctiva contact-type ERG electrode,
92 be skin contact type ERG electrode.
[specific embodiment]
In order to keep technological means of the utility model clear, it is practical new that this is further described with reference to the accompanying drawing
Type, wherein term " first ", " second ", " third " etc. are used for description purposes only, and are not understood to indicate or imply relatively heavy
The property wanted or the quantity for implicitly indicating indicated technical characteristic.
As shown in figures 1-8, a kind of portable visual electrophysiology detection system, including helmet 1, the helmet 1
For holding movable equipment 2, detecting electrode, signal amplifier, the helmet 1 also includes multi-channel structure 102, each to detect
The signal of electrode is by again being exported the signal collection of each detecting electrode to movement by multi-channel structure 102 after signal amplifier
Equipment 2.Each detecting electrode is by conducting wire connection signal amplifier, and conducting wire uses twisted pair, reduces remaining signal to each inspection
Survey the interference of signal.
Wherein, detecting electrode is ERG electrode 9, EOG electrode 8 and VEP electrode 4, and it is the respectively that wherein VEP electrode 4, which is 5,
One VEP electrode 401, the 2nd VEP electrode 402, the 3rd VEP electrode 403, the 4th VEP electrode 404, the 5th VEP electrode 405.
Signal amplifier is signal preamplifier 5 and VEP signal amplifier 41, VEP signal amplifier each VEP electricity
Pole has, and chooses a VEP electrode here and is illustrated, remaining VEP electrode is identical, i.e., VEP signal amplifier 41, which has, to adjust
Beneficial knob 42 is used to amplify the signal of VEP electrode；The signal of detection is connected after the conversion of multi-channel structure 102 by independent channel
Mobile device 2.
There is a LCD display 51 on signal preamplifier 5, is used for real-time read test data, such as impedance value.
Signal amplifier is additionally provided with independent battery module, selects standard compliant medical battery.
Signal preamplifier 5 also includes ground electrode 7 and reference electrode 6, and the ERG electrode 9 and EOG electrode 8 share
One ground electrode 7 and reference electrode 6, ERG are the potential changes for recording retina inner cell through electrode and Corneal Contact,
EOG is to record the variation of eyeball resting potential, ERG electrode and EOG electrode with the contact of eye socket two sides skin site through electrode
It is used in conjunction with a reference electrode 6.Reference electrode 6 is affixed on face skin surface.Signal preamplifier 5 is also depended on into person of modern times simultaneously
The signal source of eye, it is preferred that reference electrode 6 is placed on the inner side of preamplifier 5, that is, reference electrode 6 pastes after dressing
Temporal position.
It further include a signal amplification circuit inside signal preamplifier 5, the signal preamplifier 5 is equipped with two
A adjustable gain knob 53 is respectively intended to change ERG electrode 4 and 5 signal of EOG electrode, and the signal of detection is in signal preamplifier
5 change later by two conducting wire connecting multi-channel structures 102, wherein a wire transmission ERG electrode signal, another is led
Line transmits EOG electrode signal.
ERG electrode can be designed to that three kinds of forms are contacted with eyeball: be Corneal Contact type 9 respectively, conjunctiva contact-type 91 and
Skin contact type 92, contact one end of Corneal Contact type ERG electrode are mirror surface contact, as shown in Figure 6.Conjunctiva contact-type ERG electricity
Contact one end of pole is wire type contact, as shown in the left side Fig. 7.Contact one end of skin contact type ERG electrode is adherent contact, figure
7 is right.
ERG electrode 9, EOG electrode 8, VEP electrode 4, ground electrode 7 and reference electrode 6 by magnetic part removably with letter
Number amplifier is connected.Signal preamplifier 5 is equipped with and is correspondingly connected with ERG electrode, EOG electrode, ground electrode 7 and reference electrode 6
Magetic indicator joint.
Magnetic part connecting portion is gold-plated or plates silver chlorate.
Mobile device 2 is equipped with display screen, processor, software module and stimulating module, i.e., at 2 integrated data of mobile device
Reason, display, stimulatory function, and the electric signal that can also be will test is converted to graphical display, the software module energy in mobile device
Enough control the display that screen is needed.
Software module control display screen is stimulated, and the display screen is that the OLED that the standard of world ISCEV uses is shown
Screen.
Helmet has 5 VEP slot electrodes 31 on rack there are also VEP electrode rack 3, is in cross distribution, is used for
Place VEP electrode 4.Helmet 1 is equipped with the loosing and tightening structure 101 for holding movable equipment 2, conducive to placement different size is facilitated
Mobile device 2 or adjust mobile device 2 position.Helmet is capable of forming darkroom 103, that is, is putting mobile device 2
Seeing that mobile device is formed by space by eyes after wearing is darkroom, not light leakage.
Helmet 1 also includes two power lens 104, i.e. convex lens, eyes need to see movement by power lens 104
The screen of equipment 2, so that patient in use, shown in the brain using the stereoscopic visual effect that power lens produce spatial impression
Show, to detect the reaction of human eye under specific mode.
Fig. 1-8 display is simple eye detection, and the utility model simultaneously can also examine eyes by 2 preamplifiers of setting
It surveys, principle is identical.
Fig. 9 is the circuit design principle figure of the signal preamplifier 5 of utility model device.
The working process of the utility model is as follows:
A, suitable ERG electrode and EOG electrode are selected, ERG electrode is placed on place of the human eye close to eyeball, by EOG
Electrode is placed on different parts near the eyelid of face；
B, ground electrode is tightly attached among forehead, then corresponding magnetic part is connected to together with magetic indicator joint.
C, reference electrode is attached on human facial skin, preferably the temple position of face.
D, the conducting wire of the signal conductor and ground electrode of ERG electrode and EOG electrode is connected on preamplifier together
E, helmet is dressed, VEP electrode is also put on together with helmet together, by the bottom of VEP electrode support
Prominent position outside one the 5th VEP electrode 405 alignment people's hindbrain occipital bone, places 5 VEP electrodes, while line being connected to more
Channel design.
F, signal preamplifier is connected to the upper multi-channel structure of helmet by signal conductor；Two conducting wires its
In one be ERG electrode signal wire, another be EOG electrode signal wire, by the conducting wire of multi-channel structure be connected to movement set
Standby upper interface connects；
G, human eye is in darkroom after a certain period of time, and opening mobile device is stimulated, by built-in APP or software,
Select suitable stimulus modality；
H, the software of mobile device will record the electric signal of each electrode detection, and converts electrical signals to waveform diagram and show
Come.
I, after detection, reference electrode, ground electrode, ERG electrode, EOG electrode, VEP electrode are removed in case next time more
The electrode renewed is detected, and signal preamplifier can reuse.
ERG electrode and EOG electrode are connected a signal preamplifier by the utility model simultaneously, as picking up signal electricity
Extremely the signal of eyeball is picked up jointly, is used in conjunction with the same reference electrode, and ground electrode is as anti-interference electrode, be for
It reduces influence of the interference voltage of power grid common mode to signal and connects circuit, ERG is to record view through electrode and Corneal Contact
The potential change of nethike embrane inner cell, EOG are to record eyeball resting potential with the contact of eye socket periphery specific position through electrode
Variation, two signals be it is independent, referred to each other by the signal of two positions, to help the analysis and diagnosis and treatment of illness, take up a job as a doctor
It learns angle and sees that ERG signal is mainly the detection of retinal cell function of eyes, EOG is that supplementary reference signal is directed to retinal pigment
The Function detection of epithelium and photoreceptor complex.
Flash stimulator and wearable device are formed darkroom using helmet by the utility model, reach the condition of detection,
Wearable device is lightweight and convenient, while corresponding electrode is set up directly on helmet, more convenient to use, the number of detection
According to directly data processing display device is connected by conducting wire, testing result can be obtained in real time.
Than pervious in a kind of portable visual electrophysiology detection system sensitivity and repetition sensitivity of the utility model
Detection device is more excellent.Figure 10 is in the same detection time, and single detection comparison improves after-vision electro physiology detection system
Active electrode detection device is higher than the threshold value of pervious detection electrograph, and the sensitivity of detection improves.Figure 11 is in the same inspection
It surveys in the time, the threshold value multiplicity of the electrograph of repeated detection is more preferable.Meanwhile this preamplifier and VEP signal amplifier
Design makes EOG electrode, reference electrode, ground electrode, VEP electrode and signal amplifier itself close to signal source, and connecting line is short,
External signal interference is greatly reduced, twisted pair counteracts two Air conduct measurements and interferes with each other, and gold-plated magetic indicator joint facilitates ERG
The installation of electrode, EOG electrode, VEP electrode, gold-plated or plating silver chlorate connector can reduce contact resistance, increase conductive power,
It simultaneously can also antirust.
Compared with passive electrode, the design of the New Active electrode can improve the accuracy and repeatability of tracer signal.
The short connecting line of the design being mainly characterized by between sensor and amplifier.There is a short transmission line, it is most
External noise and interference will be eliminated.The design makes signal signal-to-noise ratio with higher, higher reproducibility, the suppression of higher common mode
System than with lower irritation level.Disposable electrode can be made in electrode, prevent from infecting, and beneficial to patient and doctor, and meet doctor
Institute's infection control standard.
Above description is merely a prefered embodiment of the utility model, on the protection scope of the utility model is not limited in
Embodiment is stated, wherein conducting wire does not use twisted pair, and other lines also can be realized the transmission of signal, not use magetic indicator joint to connect
It connects, direct conducting wire connection can also check signal, but its precision is not so good as above embodiments.
All technical solutions for belonging to the utility model principle belong to the protection scope of the utility model.For this field
Technical staff for, several improvement carried out under the premise of not departing from the principles of the present invention, these improvement should also regard
For the protection scope of the utility model.
Claims (15)
1. a kind of portable visual electrophysiology detection system, which is characterized in that including helmet, the helmet is for putting
Mobile device, detecting electrode, signal amplifier are set, the helmet also includes multi-channel structure, the signal of each detecting electrode
By the way that the signal collection of each detecting electrode is exported to mobile device by multi-channel structure again after signal amplifier.
2. a kind of portable visual electrophysiology detection system according to claim 1, which is characterized in that the detection electricity
Extremely ERG electrode, EOG electrode and VEP electrode.
3. a kind of portable visual electrophysiology detection system according to claim 2, which is characterized in that the signal amplification
Device is signal preamplifier and VEP signal amplifier, and signal preamplifier has adjustable gain knob for amplifying ERG electrode
With EOG electrode signal, VEP signal amplifier has adjustable gain knob for amplifying the signal of VEP electrode；The signal of detection is more
Mobile device is connected by independent channel after channel design conversion.
4. a kind of portable visual electrophysiology detection system according to claim 3, which is characterized in that advance signal amplification
There is a LCD display on device, is used for real-time read test data.
5. a kind of portable visual electrophysiology detection system according to claim 3, which is characterized in that signal amplifier is also
Equipped with independent battery module.
6. a kind of portable visual electrophysiology detection system according to claim 3, which is characterized in that the advance signal
Amplifier also includes ground electrode and reference electrode, and the ERG electrode and EOG electrode share a ground electrode and reference electrode.
7. a kind of portable visual electrophysiology detection system according to claim 3, which is characterized in that ERG electrode, EOG
Electrode, VEP electrode, ground electrode and reference electrode are removably connected with respective signal amplifier by magnetic part.
8. a kind of portable visual electrophysiology detection system according to claim 7, which is characterized in that the magnetic part
Connecting portion is gold-plated or plates silver chlorate.
9. a kind of portable visual electrophysiology detection system according to claim 7, which is characterized in that ERG electrode has three
A type is Corneal Contact type, conjunctiva contact-type and skin contact type respectively.
10. a kind of portable visual electrophysiology detection system according to claim 1, which is characterized in that the movement
Equipment is equipped with display screen, processor, software module and stimulating module, the i.e. processing of mobile device integrated data, display, stimulation function
Can, and the electric signal that can also be will test is converted to graphical display.
11. a kind of portable visual electrophysiology detection system according to claim 10, which is characterized in that the software mould
Block control display screen is stimulated, and the display screen is the OLED display screen that the standard of world ISCEV uses.
12. a kind of portable visual electrophysiology detection system according to claim 1, which is characterized in that described wears
Equipment has 5 VEP slot electrodes on rack there are also VEP electrode rack, is in cross distribution, for placing VEP electrode.
13. a kind of portable visual electrophysiology detection system according to claim 1, which is characterized in that helmet is set
There is the loosing and tightening structure for holding movable equipment.
14. a kind of portable visual electrophysiology detection system according to claim 1, which is characterized in that helmet energy
Darkroom is enough formed, i.e., seeing that mobile device is formed by space by eyes after putting mobile device wearing is darkroom, is not leaked
Light.
15. a kind of portable visual electrophysiology detection system according to claim 1, which is characterized in that described wears
Equipment also includes two power lens, and eyes need to see the screen of mobile device by power lens.
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| CN107898459A (en) * | 2017-09-12 | 2018-04-13 | 深圳麦格米特电气股份有限公司 | A kind of portable visual electrophysiology detecting system |
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| CN107898459A (en) * | 2017-09-12 | 2018-04-13 | 深圳麦格米特电气股份有限公司 | A kind of portable visual electrophysiology detecting system |
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