CN208647604U - A kind of biological sample storage device - Google Patents
A kind of biological sample storage device Download PDFInfo
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- CN208647604U CN208647604U CN201820811684.7U CN201820811684U CN208647604U CN 208647604 U CN208647604 U CN 208647604U CN 201820811684 U CN201820811684 U CN 201820811684U CN 208647604 U CN208647604 U CN 208647604U
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Abstract
A kind of biological sample storage device, comprising: Installation cabinet, upper end opening, one side set opening, and the other side sets aperture；Housing is set in Installation cabinet；Liquid nitrogen container placing table is set to side in Installation cabinet, is body structure, inside sets frame structure, forms several compartments；Several liquid nitrogen containers, in the compartment of liquid nitrogen container placing table, for storing cryopreservation tube；Liquid nitrogen container hoisting mechanism is set to Installation cabinet upper port frame, is located above liquid nitrogen container placing table；The mobile clamping device of three-dimensional, is set to Installation cabinet housing lower end inside, is located above liquid nitrogen container hoisting mechanism；It includes three-dimensional moving mechanism and the first, second grabbing device thereon；Transferring box transmission mechanism, by fixed mount setting in by liquid nitrogen container placing table, corresponding Installation cabinet is open in the Installation cabinet；Transfer tank, for shifting transport cryopreservation tube；Transferring box, the transfer tank is set in transferring box, for storing transfer tank；Controller is set on the inside of Installation cabinet, by transferring box transmission mechanism.
Description
Technical field
The utility model belongs to biological sample field of storage, in particular to a kind of biological sample automated storing equipment.
Background technique
Biological sample bank is that standardization collects, processing, stores health and the large biological molecule of disease organism, cell, group
Knit the equipment with organ equal samples.Before storing, need to cool down by program makes its suspend mode to biological sample, is then stored in liquid nitrogen and holds
In device or profound hypothermia refrigerator.For certain specific biological samples, storing process needs to guarantee full cold chain protection, and whole process all needs
, to protect its bioactivity, the damage of multigelation is avoided in profound hypothermia environment.
Existing profound hypothermia biological sample is automatically stored equipment and several hand baskets, each hand basket is generally arranged in liquid nitrogen container
Multiple freezing storing box are placed in inside, and storage is equipped with the cryopreservation tube of biological sample in freezing storing box, are taken cryopreservation tube using automatic mechanism
Out or it is stored in.By taking 2 492 663 A2 of European patent EP as an example, 6 fan-shaped hand baskets, each hand basket are equipped in a liquid nitrogen container
On there are several to freeze disk, freeze inside disk equipped with cryopreservation tube；Two fan-shaped mouths are opened at the top of liquid nitrogen container, are taken out for hand basket；Liquid
There is an airtight chamber above nitrogen tank, inside is equipped with automatic mechanism and refrigerating plant；When needing to be stored in or taking out cell,
Automatic mechanism lifts hand basket, and taking-up freezes disk, is stored in or takes out cryopreservation tube later, freezes disk by refrigerating plant maintenance
Low temperature.
All mechanical parts of the technical solution are also relatively high to automatic mechanism technical requirements all in low temperature environment,
It is difficult to have movement mechanism to be able to satisfy that performance at this temperature is unaffected, the difficulty of realization is big, at high cost, poor reliability.Due to
It needs to freeze to entire airtight chamber, accesses cryopreservation tube every time and require to consume a large amount of liquid nitrogen, absorption chamber is evaporated by it
Interior heat freezes, and liquid nitrogen can not recycle, cause very big waste.In addition to this, since there are the skies lifted enough for hand basket needs
Between, it freezes disk and needs to cause that liquid nitrogen container inner space utilization rate is lower, and amount of storage is less there are the space removed enough.Together
When due to hand basket itself architectural characteristic, upper and lower turning part cross-sectional area is small, and thermally conductive flux from top to bottom is lower, top freeze
The biological sample of deposit largely leans on the nitrogen heat convection of evaporation to guarantee low temperature, and very thick closure head insulation layer is needed to maintain
The nitrogen on top is in low temperature, increases the height dimension and cost of equipment.Importantly, such equipment in the single branch of access or
During a small amount of sample of person, in the presence of by the great amount of samples of a sector, carrying out movement lifts leaves original storage simultaneously
Position, so as to cause the adverse effect of fluctuating change and mechanical oscillation to sample foreign environment temperature.
Equipment all machinery in full cold chain access procedure are not only automatically stored in the above common biological sample storage device
Component is in low temperature environment, easily causes the damage of electric elements, and conventional storage equipment pass-through box transmits transferring box
When cannot achieve full-automatic transfer, reduce user's convenience.
Summary of the invention
The purpose of this utility model is to provide a kind of biological sample storage devices, solve automation integrated formula access and freeze
The problem of pipe, reduces the adverse effect of biological sample fluctuation in cryopreservation tube, improves the efficiency of access cryopreservation tube, bring for user
Convenience.
To achieve the above purpose, the technical solution of the present invention is:
A kind of biological sample storage device comprising:
Installation cabinet, upper end opening, one side set opening, and the other side sets aperture；Housing is set in Installation cabinet；
Liquid nitrogen container placing table is set to side in the Installation cabinet, is body structure, inside sets frame structure, if being formed
Dry compartment；
Several liquid nitrogen containers, in the compartment of the liquid nitrogen container placing table, for storing cryopreservation tube；
Liquid nitrogen container hoisting mechanism is set to the Installation cabinet upper port frame, is located above the liquid nitrogen container placing table；
The mobile clamping device of three-dimensional, is set to the Installation cabinet housing lower end inside, is located at the liquid nitrogen container hoisting mechanism
Top；It includes three-dimensional moving mechanism and the first, second grabbing device thereon；
Transferring box transmission mechanism, by fixed mount setting in the Installation cabinet by liquid nitrogen container placing table, corresponding Installation cabinet
Opening；
Transfer tank, for shifting transport cryopreservation tube；
Transferring box, the transfer tank is set in transferring box, for storing transfer tank；
Controller is set on the inside of the Installation cabinet, by transferring box transmission mechanism.
Preferably, the liquid nitrogen container hoisting mechanism includes,
Two support plates, size are matched with the Installation cabinet upper port internal diameter, set match with the liquid nitrogen container outer diameter thereon
Through-hole；Two support plates are arranged in parallel up and down；The transfer through-hole placed for transfer tank is set in the middle part of two support plates；
Four pairs of supporting blocks arranged up and down, are respectively arranged at support plate four corners, and supporting block respectively corresponds support plate；
Four screw rods are arranged in four pairs of supporting blocks respectively；The work of two with wire rod thread cooperation are set on every screw rod
Motion block, two movable block are connected to two supporting blocks being arranged on screw rod；
Four belt pulleys are respectively arranged at four screw rod lower parts, and by transmission band connection four belt pulleys；
Four sector gears are respectively arranged at four screw lower ends；
One drive rod, one end protrude into from a side corner sections of the Installation cabinet, set on the end and engage with the sector gear
Driving sector gear.
Preferably, the three-dimensional mobile clamping device includes,
Two X-direction guide rails and thereon X to sliding block, be arranged in parallel on the inside of the Installation cabinet housing lower port respectively two
Opposite side wall；
X-direction driving mechanism, including,
Two X are arranged in parallel in two X-direction guide rails side to driving screw rod respectively；Driving screw rod one end sets first
Sector gear；
Two X are set to the X on driving screw rod to drive block, cooperate with X to driving wire rod thread；The X is to drive block
It is connect with X on X-direction guide rail to sliding block；
X is set between two X-direction rail ends to driving motor, is fixed on Installation cabinet cover by mounting plate
Shell inner wall；X sets X to driving sector gear to driving motor output shaft；
Two drive shafts, both ends set X to sector gear respectively, and fan respectively to the X of driving motor output shaft to driving with X
The the first sector gear engagement of shape gear and X on driving screw rod；
Two Y-direction guide rails and thereon the first, second Y-direction sliding block, two Y-direction guide rail both ends be respectively arranged at two X to
Drive X of two X on screw rod on drive block and two X-direction guide rails on sliding block；
Y-direction driving mechanism, including,
Two Y-directions drive screw rod, are arranged in parallel in the two Y-directions guide rail side respectively；Y-direction driving screw rod one end sets second
Sector gear；
Two Y-direction drive blocks are set on the Y-direction driving screw rod, with Y-direction driving wire rod thread cooperation；The Y-direction drive block
It is connect with the first, second Y-direction sliding block on two Y-direction guide rails；
Second Y-direction driving motor is set to two Y-direction rail ends, is fixed on the installation by mounting plate
Cabinet encloser inner wall；First, second Y-direction driving motor output shaft sets the first, second Y-direction driving sector gear, first, second Y
The second sector gear engagement of two Y-directions driving screw rod one end is distinguished to driving sector gear；
First Z-direction mechanism, the first Y-direction sliding block being set on the Y-direction guide rail；Including,
First Z-direction fixed plate, horizontal arrangement, one side be connected to the first Y-direction sliding block on the Y-direction guide rail and
On the Y-direction driving screw rod on Y-direction drive block, three through-holes of interval setting along its length in the first Z-direction fixed plate；
Lifting frame, including,
Two guide rods are arranged in two through-holes for being located at two sides in the first Z-direction fixed plate；
Upper and lower connecting rod is connected to the upper and lower ends of two guide rod；
First Z-direction drives screw rod, is arranged in the first Z-direction fixed plate and is located in the middle through-hole, upper and lower side connection
In the middle part of the upper and lower connecting rod；The worm gear being engaged with is set on first Z-direction driving screw rod；
First Z-direction driving motor is vertically arranged at side in the first Z-direction fixed plate, and output shaft end is set and institute
State worm gear meshed gears；
Second Z-direction mechanism is set to the Y-direction guide rail ' on the second Y-direction sliding block；
Z-direction guide rail and thereon Z-direction sliding block, Z-direction guide rail are vertically arranged at the second Y-direction sliding block lateral surface and the Y-direction
Drive Y-direction drive block on screw rod；
Second Z-direction drives screw rod, is arranged in parallel in Z-direction guide rail side, the upper end sets transmission gear；
Z-direction drive block is set on the second Z-direction driving screw rod, with the driving wire rod thread cooperation of the second Z-direction；The Z-direction
Drive block is connect with Z-direction sliding block on Z-direction guide rail；
2nd Z driving motor is vertically arranged at the second Z-direction driving screw rod side, and output shaft sets driving gear, and
Couple the transmission gear that second Z-direction drives screw rod upper end by synchronous belt；
First, second grabbing device is respectively arranged at lifting frame and the 2nd side Z of first Z-direction mechanism
To on the Z-direction sliding block of mechanism.
Preferably, first grabbing device includes,
Screw rod is clamped, is arranged in parallel in by bracket below the lower link of first Z-direction mechanism lifting frame；
Two clamping jaws are set to the clamping screw rod, and cooperate with clamping wire rod thread；
First clamping motor, lower link one end of the lifting frame is vertically to by mounting plate, output shaft sets third
Bevel gear, correspondingly, clamping screw rod one end sets the 4th bevel gear engaged with the third bevel gear.
Preferably, the second grabbing device includes,
Fixing sleeve, one side are fixed on the Z-direction sliding block of second Z-direction mechanism, and fixing sleeve top bottom surface sets through-hole；
Rack gear is arranged in the fixing sleeve top bottom surface and sets through-hole；
Second clamping motor, is set to the fixing sleeve lateral surface, and output shaft protrudes into fixing sleeve, output shaft end set with
Rack gear meshed gears；
Clamping piece is set to the rack gear lower end.
Preferably, further include a sighting device, be set to Z-direction rail back in second Z-direction mechanism.
Preferably, the transferring box transmission mechanism, including,
Fixed pedestal is set in the Installation cabinet by liquid nitrogen container placing table, corresponding Installation cabinet opening, and fixed pedestal includes
Bottom plate both side plate and its fixed frame of front side；
Upper mounted plate is horizontally placed on lower part in the fixed pedestal, and horizontal one fixed column of projection of front end face, this is fixed
Column sets through-hole along axial direction；
Front door, its underpart are pivotally connected to the fixed column on front side of fixed plate, size and the fixed frame
Match；
Preceding door drive mechanism, comprising:
Two screw rods, are horizontally placed on the fixed pedestal side plate lateral surface respectively, and the fixed bracket of screw both end is connected to institute
State fixed pedestal side plate；The sliding block being threadedly engaged therewith is set on screw rod；
Two connecting rods, one end of two connecting rods are movably connected on two sliding block lateral surfaces on two screw rod, two connecting rods it is another
End is movably connected on a connecting seat, which is connected to front door medial surface lower part two sides；
One driving device, couples described screw rod one end, which is connected to the fixed pedestal bottom by mounting base
On plate；
Transmission mechanism, including,
Two telescopic joints are horizontally placed on upper mounted plate both sides of the upper end in the fixed pedestal, each telescopic joint respectively
Including,
Mounting plate is horizontally placed on upper mounted plate both sides of the upper end in the fixed pedestal；
Fixed plate is slidably connected on the inside of the mounting plate；Sliding panel is slidably connected on the inside of the fixed plate；
Two toothed racks, bottom surface are dentalation, are installed on the fixed plate bottom surface of described two telescopic joints；
Transferring box holds plate, and two sides are connected to the inside of described two telescopic joint sliding panels；
Two transmitting driving motors are symmetrically disposed on the transferring box and hold board bottom Middle face two sides, transmit driving motor
Output shaft it is vertical with rack axis, output shaft end sets the gear being engaged with rack；Wherein a transmitting driving motor passes through
Mounting bracket is connected to the transferring box and holds board bottom face, and another transmitting driving motor is connected to the fixation by mounting bracket
Pedestal bottom plate upper surface.
Preferably, the driving device includes driving motor, is connected on the fixed pedestal bottom plate by mounting base,
Motor output shaft end sets a bevel gear；Two drive shafts, are located at driving motor two sides, and the two sides of two drive shafts are solid by support
Due on the fixed pedestal bottom plate, drive shaft both ends set bevel gear, the bevel gear and driving motor output shaft of one end
The engagement of end bevel gear；Two connecting shafts, are vertically arranged at the other end of two drive shaft respectively, and the both ends of connecting shaft set umbrella
Shape gear, the bevel gear of one end are engaged with the bevel gear of drive shaft；Described screw rod one end sets bevel gear, connecting shaft
Other end bevel gear is engaged with the bevel gear of screw rod one end；Driving motor drives drive shaft to drive silk by connecting shaft screw rod
Sliding block on bar is mobile, and the connecting rod for being connected to one end on sliding block pushes and pulls the front door, realizes open and close control.
Preferably, further include a cap sheathing mechanism, be set to the fixed pedestal upper end, including, upper cover fixed frame, including
Two fixed links and connecting rod；Two fixed links are vertical with side plate, and two fixed link medial surfaces set guide groove along its length；Upper cover door,
Two sides set link block, and the projection of link block lateral surface can be embedded at the salient point of the two fixed links medial surface guide groove；Two upper covers are solid
Fixed rack, it is U-shaped, it is arranged in parallel in front of and after the upper cover fixed frame, it is fixed that the fixed bracket both ends of upper cover are connected to two
Bar；First belt pulley is set to the fixed mid-stent of the upper cover before the upper cover fixed frame；Upper cover driving motor,
The fixed mid-stent side of another upper cover after being connected to the bracket upper cover fixed frame by mounting plate, output shaft
If the second belt pulley, and the first belt pulley is coupled by driving belt；Coupling block connection upper cover door is set on driving belt.
When user opens transferring box transmission mechanism by controller, front door is opened, and the starting of transferring box transmission mechanism is driven
Dynamic transferring box holds plate and continues to move along, and transferring box is placed on transferring box and held on plate by user, then passes through controller again
Transferring box is transferred in pass-through box containing tank by control.
Because when original state, upper cover door (being similar to skylight) is located above transferring box, contained when transferring box is transferred to pass-through box
After putting in slot, electric motor starting, and transmission belt is driven to drive upper cover door mobile to side, skylight is opened above transferring box, and three-dimensional is moved
Dynamic grabbing device starting, when the first grabbing device is moved to right above transferring box, transferring box is uncapped, in the entrance of the first grabbing device
The transfer tank placed in turnning box and clamp column transferring box, and transferring box is removed, and transfer tank is moved to above transfer through-hole simultaneously
It places in it, the mobile grabbing device starting of three-dimensional so that the first grabbing device has clamped liquid nitrogen top ends of cans, and top cover is moved to
Above other liquid nitrogen containers, after then the suction tube device of the second grabbing device extracts the cryopreservation tube in transfer tank, suction pipe is driven
Device suction nozzle is moved to above the aluminum pipe in transfer tank, and cryopreservation tube is placed in aluminum pipe, and suction nozzle removes, and the first grabbing device is again
Secondary top cover placement original place can be completed deposits pipe movement.
The utility model has the beneficial effects that
The utility model realizes the problem of integral type access cryopreservation tube, and biological sample fluctuation is unfavorable in reduction cryopreservation tube
It influences, improves the efficiency of access cryopreservation tube, be offering convenience property of user.
Detailed description of the invention
Fig. 1 is the perspective view of the utility model embodiment；
Fig. 2 is the stereogram exploded view of the utility model embodiment；
Fig. 3 is the stereogram exploded view of liquid nitrogen container placing table and several liquid nitrogen containers in the utility model embodiment；
Fig. 4 is the stereogram exploded view of liquid nitrogen container placing table in the utility model embodiment；
Fig. 5 is the structural schematic diagram of liquid nitrogen container hoisting mechanism in the utility model embodiment；
Fig. 6 is the portion the A enlarged diagram of Fig. 5；
Fig. 7 is the perspective view 1 of three-dimensional mobile clamping device and cap sheathing mechanism in the utility model embodiment；
Fig. 8 is the perspective view 2 of three-dimensional mobile clamping device and cap sheathing mechanism in the utility model embodiment；
Fig. 9 is the perspective view 3 of three-dimensional mobile clamping device in the utility model embodiment；
Figure 10 is the perspective view 4 of three-dimensional mobile clamping device in the utility model embodiment；
Figure 11 is the perspective view of the first Z-direction mechanism and the first grabbing device in the utility model embodiment；
Figure 12 is the stereogram exploded view of the first Z-direction mechanism and the first grabbing device in the utility model embodiment；
Figure 13 is the perspective view 1 of the second Z-direction mechanism and the second grabbing device in the utility model embodiment；
Figure 14 is the perspective view 2 of the second Z-direction mechanism and the second grabbing device in the utility model embodiment；
Figure 15 is the stereogram exploded view of the second Z-direction mechanism and the second grabbing device in the utility model embodiment；
Figure 16 is the stereoscopic schematic diagram 1 of transferring box transmission mechanism in the utility model embodiment；
Figure 17 is the stereoscopic schematic diagram 2 of transferring box transmission mechanism in the utility model embodiment；
Figure 18 is the front view of transferring box transmission mechanism in the utility model embodiment；
Figure 19 is stereo decomposing Fig. 1 of transferring box transmission mechanism in the utility model embodiment；
Figure 20 is stereo decomposing Fig. 2 of transferring box transmission mechanism in the utility model embodiment；
Figure 21 is the perspective view of transferring box transmission mechanism in the utility model embodiment；
Figure 22 is the stereogram exploded view of transferring box transmission mechanism in the utility model embodiment.
Specific embodiment
Referring to FIG. 1 to FIG. 22, a kind of biological sample storage device of the utility model comprising:
Installation cabinet 1, upper end opening, one side set opening 101, and the other side sets aperture 102；Housing 103 is set in Installation cabinet 1；
Liquid nitrogen container placing table 2 is set to side in the Installation cabinet 1, is body structure, inside sets frame structure, is formed
Several compartments；
Several liquid nitrogen containers 3, in the compartment of the liquid nitrogen container placing table 2, for storing cryopreservation tube；
Liquid nitrogen container hoisting mechanism 4 is set to the 1 upper port frame of Installation cabinet, is located at 2 top of liquid nitrogen container placing table；
The mobile clamping device 5 of three-dimensional, is set to 1 housing of Installation cabinet, 103 lower end inside, is located at the liquid nitrogen container and is promoted
4 top of mechanism；It includes three-dimensional moving mechanism and the first, second grabbing device 6,7 thereon, wherein the first grabbing device 6 is grabbed
Take transfer tank 9；Second grabbing device 7 is to freeze suction tube device；
Transferring box transmission mechanism 8, by fixed mount setting in by liquid nitrogen container placing table 2, correspondence is installed in the Installation cabinet 1
The opening of cabinet 1 101；
Transfer tank 9, for shifting transport cryopreservation tube；
Transferring box 11, the transfer tank 36 is set in transferring box 11, for storing transfer tank 9；
Controller 12 is set on the inside of the Installation cabinet 1, by transferring box transmission mechanism 8；
Further, the liquid nitrogen container hoisting mechanism 4 includes,
Two support plates 41,41 ', size are matched with the 1 upper port internal diameter of Installation cabinet, are set thereon and the liquid nitrogen container 3
The matched through-hole 411 of outer diameter；Two support plates 41, about 41 ' are arranged in parallel；It is set in the middle part of two support plates 41 for the placement of transfer tank 9
Transfer through-hole 412；
Four pairs of supporting blocks 42,42 ' (by taking supporting block 42,42 ' as an example, similarly hereinafter) arranged up and down, are respectively arranged at support plate
41,41 ' four corners, supporting block 42,42 ' respectively correspond support plate 41,41 '；
Four screw rods 43 (by taking screw rod 43 as an example, similarly hereinafter), are arranged in four pairs of supporting blocks 42,42 ' respectively；Every screw rod
Two movable blocks being threadedly engaged with screw rod 43 are set on 43, which is connected to two supports being arranged on screw rod 43
Block 42,42 '；
Four belt pulleys 44 are respectively arranged at four screw rods, 43 lower part, and connect four skins by a conveyer belt 45
Belt wheel 44；
Four sector gears 46 are respectively arranged at four screw rods, 43 lower end；
One side corner sections of one drive rod 47, one end from the Installation cabinet 1 protrude into, and set on the end and the sector gear 46
The driving sector gear 48 of engagement.
Further, the three-dimensional mobile clamping device 5 includes,
Two X-direction guide rails 51,51 ' and thereon X are arranged in parallel in the Installation cabinet 1 respectively and cover to sliding block 511,511 '
Two opposite side walls on the inside of 103 lower port of shell；
X-direction driving mechanism 52, including,
Two X are arranged in parallel in described two to driving screw rod 521 (by side X to for driving screw rod 521, similarly hereinafter) respectively
Root X-direction guide rail 51,51 ' sides；Driving 521 one end of screw rod sets the first sector gear；
Two X are set to the X on driving screw rod 521 to drive block 522, are threadedly engaged with X to driving screw rod 521；
X is set between two X-direction guide rails 51,51 ' ends, is fixed on by mounting plate to driving motor 523
1 housing of Installation cabinet, 103 inner wall；X sets X to driving sector gear to 523 output shaft of driving motor；
Two drive shafts 524, both ends set X to sector gear respectively, and respectively with X from X to 523 output shaft of driving motor to
Drive the first sector gear engagement of sector gear and X on driving screw rod 521；
Two Y-direction guide rails 53,53 ' and the thereon first, second Y-direction sliding block 531,531 ', two Y-direction guide rails 53,53 ' both ends
Be respectively arranged at two Xs X to drive block 522 and two piece X-direction guide rails 51,51 ' on of two X on driving screw rod 521 to
On sliding block 511,511 '；
Y-direction driving mechanism 54, including,
Two Y-directions drive screw rod 541,541 ', are arranged in parallel in the two Y-directions guide rail 53,53 ' sides respectively；Y-direction driving
541 one end of screw rod sets the second sector gear；
Two Y-direction drive blocks 542,542 ' are set on Y-direction driving screw rod 541,541 ', with Y-direction driving screw rod 541,
541 ' are threadedly engaged；
Second Y-direction driving motor 543,544 is set to two Y-direction guide rails 53,53 ' ends, solid by mounting plate
Due to 1 housing of Installation cabinet, 103 inner wall；First, second Y-direction driving motor 543,544 output shafts set the drive of the first, second Y-direction
Dynamic sector gear, first, second Y-direction drive sector gear to distinguish the second sector that two Y-directions drive screw rod 541,541 ' one end
Gear engagement；
First Z-direction mechanism 55, the first Y-direction sliding block 531 being set on the Y-direction guide rail 53；Including,
First Z-direction fixed plate 551, horizontal arrangement, one side are connected to the first Y-direction on the Y-direction guide rail 53
On sliding block 531 and Y-direction driving screw rod 541 on Y-direction drive block 542；It is spaced along its length in first Z-direction fixed plate 551
Three through-holes are set；
Lifting frame 552, including,
Two guide rods 5521 are arranged in two through-holes for being located at two sides in the first Z-direction fixed plate 551；
Upper and lower connecting rod 553,554, is connected to the upper and lower ends of two guide rod 5521；
First Z-direction drives screw rod 555, is arranged in the first Z-direction fixed plate 551 and is located in the middle through-hole, above and below
End is connected to the middle part of the upper and lower connecting rod 553,554；The worm gear 556 being engaged with is set on first Z-direction driving screw rod 555；
First Z-direction driving motor 557 is vertically arranged at side in the first Z-direction fixed plate 551, output shaft end
If with 556 meshed gears of worm gear；
Second Z-direction mechanism 56, the second Y-direction sliding block 531 ' being set on the Y-direction guide rail 53 '；
Z-direction guide rail 561 and its Z-direction sliding block 562, Z-direction guide rail 561 are vertically arranged at the 531 ' outside of the second Y-direction sliding block
Two Y-direction drive blocks 542 ' on face and Y-direction driving screw rod 541 '；
Second Z-direction drives screw rod 563, is arranged in parallel in 561 side of Z-direction guide rail, the upper end sets transmission gear；
Z-direction drive block 564 is set on the second Z-direction driving screw rod 563, drives 563 screw thread of screw rod with the second Z-direction
Cooperation；The Z-direction drive block 564 is connect with Z-direction sliding block 562 on Z-direction guide rail 561；
2nd Z driving motor 565, is vertically arranged at the second Z-direction driving 563 side of screw rod, and output shaft sets driving
Gear, and the transmission gear that second Z-direction drives 563 upper end of screw rod is coupled by synchronous belt；
First, second grabbing device 6,7 is respectively arranged at 552 He of lifting frame of first Z-direction mechanism 55
On the Z-direction sliding block 562 of second Z-direction mechanism 56.
Also, first grabbing device 6 includes,
Screw rod 61 is clamped, the lower link of first Z-direction mechanism, 55 lifting frame 552 is arranged in parallel in by bracket
554 lower sections；
Two clamping jaws 62,62 ' are set to the clamping screw rod 61, and are threadedly engaged with clamping screw rod 61；
First clamping motor 63,554 one end of lower link of the lifting frame 552 is vertically to by mounting plate, is exported
Axis sets third bevel gear 64, correspondingly, clamping 61 one end of screw rod sets the 4th umbrella shape tooth engaged with the third bevel gear 64
Wheel 65.
Further more, the second grabbing device 7 includes,
Fixing sleeve 71, one side are fixed on the Z-direction sliding block 562 of second Z-direction mechanism 56, the top of fixing sleeve 71, bottom
Face sets through-hole；
Rack gear 72 is arranged in the top of fixing sleeve 71, bottom surface sets through-hole；
Second clamping motor 73, is set to 71 lateral surface of fixing sleeve, output shaft protrudes into fixing sleeve 71, output shaft end
Portion is set and 72 meshed gears 74 of rack gear；
Clamping piece 75 is set to 72 lower end of rack gear.
Preferably, further include a sighting device 13, be set to Z-direction guide rail 561 in second Z-direction mechanism 56 and carry on the back
Face.
Preferably, the transferring box transmission mechanism 8, including,
Fixed pedestal 81 is set in the Installation cabinet 1 by liquid nitrogen container placing table 2, the corresponding opening of Installation cabinet 1 101, fixed
Pedestal 81 includes bottom plate, both side plate and its fixed frame of front side；
Upper mounted plate 86, is horizontally placed on lower part in the fixed pedestal 81, horizontal one fixed column 87 of projection of front end face,
The fixed column 87 sets through-hole along axial direction；
Front door 82, its underpart are pivotally connected to the fixed column 87 of 86 front side of fixed plate, size with it is described solid
Determine frame matching；
Preceding door drive mechanism 83, comprising:
Two screw rods 831 are horizontally placed on the 81 side plate lateral surface of fixed pedestal, the fixed bracket in 831 both ends of screw rod respectively
It is connected to 81 side plate of fixed pedestal；The sliding block 832 being threadedly engaged therewith is set on screw rod 831；
Two connecting rods 833, one end of two connecting rods are movably connected on two sliding blocks, 832 lateral surface on two screw rod 831, and two connect
The other end of bar 833 is movably connected on a connecting seat, which is connected to the 82 medial surface lower part two sides of front door；
One driving device 84, couples described 831 one end of screw rod, which is connected to the fixation by mounting base
On 81 bottom plate of pedestal；
Transmission mechanism 85, including,
It is each to be horizontally placed on 86 both sides of the upper end of upper mounted plate in the fixed pedestal 81 respectively for two telescopic joints 851
Telescopic joint 851 includes,
Mounting plate 8511 is horizontally placed on 86 both sides of the upper end of upper mounted plate in the fixed pedestal；
Fixed plate 8512 is slidably connected on the inside of the mounting plate；
Sliding panel 8513 is slidably connected on the inside of the fixed plate；
Two toothed racks 852, bottom surface are dentalation, are installed on 8512 bottom surface of fixed plate of described two telescopic joints 851；
Transferring box holds plate 853, and two sides are connected to the inside of described two 851 sliding panels 8513 of telescopic joint；
Two transmitting driving motors 854,855 are symmetrically disposed on the transferring box and hold 853 bottom surface on both sides of the middle of plate, pass
The output shaft for passing driving motor 854,855 is vertical with 852 axis of rack gear, and output shaft end is set and 852 meshed gears of rack gear；Its
In a transmitting driving motor transferring box be connected to by mounting bracket hold 853 bottom surface of plate, another transmitting driving motor
The 81 bottom plate upper surface of fixed pedestal is connected to by mounting bracket.
Preferably, the driving device 84 includes,
Driving motor 841 is connected on 81 bottom plate of fixed pedestal by mounting base, and motor output shaft end sets a umbrella
Shape gear；
Two drive shafts 842 (by taking side drive shaft 842 as an example, similarly hereinafter) are located at 841 two sides of driving motor, two drive shafts 842
Two sides be fixed on 81 bottom plate of fixed pedestal by support, drive shaft both ends set bevel gear, the umbrella shape tooth of one end
Wheel is engaged with 842 output shaft end bevel gear of driving motor；
Two connecting shafts 843, are vertically arranged at the other end of two drive shaft 842 respectively, and the both ends of connecting shaft 843 set umbrella
The bevel gear of shape gear, one end is engaged with the bevel gear of drive shaft 842；Described 831 one end of screw rod sets bevel gear, even
The other end bevel gear of spindle 843 is engaged with the bevel gear of 831 one end of screw rod；Driving motor 841 drives drive shaft to pass through
Connecting shaft 843, screw rod 831 drive the sliding block 832 on screw rod 831 mobile, and the connecting rod 833 for being connected to one end on sliding block 832 pushes away
The front door 82 is drawn, realizes open and close control.
Preferably, further include a cap sheathing mechanism 10, be set to 81 upper end of fixed pedestal, including,
Upper cover fixed frame 101, including two fixed links 1011 and connecting rod 1012；Two fixed links 1011 are vertical with side plate,
Two fixed links, 1011 medial surface sets guide groove 10111 along its length；
Upper cover door 102, two sides set link block 103, and 103 lateral surface projection of link block can be embedded at two fixed link
The salient point of 1011 medial surface guide grooves 10111；
Two upper covers fix bracket 104,104 ', U-shaped, are arranged in parallel in 101 front and back of upper cover fixed frame, and upper cover is solid
101 both ends of fixed rack are connected to two fixed links 1011；
First belt pulley 105 is set to fixed 104 middle part of bracket of the upper cover before the upper cover fixed frame 101；
Upper cover driving motor 106, on another after the bracket upper cover fixed frame 101 is connected to by mounting plate
Cover fixed 104 ' middle part side of bracket, output shaft sets the second belt pulley (not shown), and by transmission skin 107 with connection the
One belt pulley 105；A coupling block 108 connection upper cover door 102 is set on driving belt 107.
Claims (9)
1. a kind of biological sample storage device characterized by comprising
Installation cabinet, upper end opening, one side set opening, and the other side sets aperture；Housing is set in Installation cabinet；
Liquid nitrogen container placing table is set to side in the Installation cabinet, is body structure, inside sets frame structure, formed it is several every
Room；
Several liquid nitrogen containers, in the compartment of the liquid nitrogen container placing table, for storing cryopreservation tube；
Liquid nitrogen container hoisting mechanism is set to the Installation cabinet upper port frame, is located above the liquid nitrogen container placing table；
The mobile clamping device of three-dimensional, is set to the Installation cabinet housing lower end inside, is located above the liquid nitrogen container hoisting mechanism；
It includes three-dimensional moving mechanism and the first, second grabbing device thereon；
Transferring box transmission mechanism, by fixed mount setting in by liquid nitrogen container placing table, corresponding Installation cabinet is open in the Installation cabinet；
Transfer tank, for shifting transport cryopreservation tube；
Transferring box, the transfer tank is set in transferring box, for storing transfer tank；
Controller is set on the inside of the Installation cabinet, by transferring box transmission mechanism.
2. biological sample storage device as described in claim 1, which is characterized in that the liquid nitrogen container hoisting mechanism includes,
Two support plates, size are matched with the Installation cabinet upper port internal diameter, are set thereon matched logical with the liquid nitrogen container outer diameter
Hole；Two support plates are arranged in parallel up and down；The transfer through-hole placed for transfer tank is set in the middle part of two support plates；
Four pairs of supporting blocks arranged up and down, are respectively arranged at support plate four corners, and supporting block respectively corresponds support plate；
Four screw rods are arranged in four pairs of supporting blocks respectively；The movable block of two with wire rod thread cooperation are set on every screw rod,
Two movable block is connected to two supporting blocks being arranged on screw rod；
Four belt pulleys are respectively arranged at four screw rod lower parts, and by transmission band connection four belt pulleys；
Four sector gears are respectively arranged at four screw lower ends；
One drive rod, one end are protruded into from a side corner sections of the Installation cabinet, and the drive engaged with the sector gear is set on the end
Dynamic sector gear.
3. biological sample storage device as described in claim 1, which is characterized in that the three-dimensional moves clamping device and includes,
Two X-direction guide rails and thereon X are arranged in parallel in two opposite on the inside of the Installation cabinet housing lower port respectively to sliding block
Side wall；
X-direction driving mechanism, including,
Two X are arranged in parallel in two X-direction guide rails side to driving screw rod respectively；Driving screw rod one end sets the first sector
Gear；
Two X are set to the X on driving screw rod to drive block, cooperate with X to driving wire rod thread；The X is to drive block and X
X is connected to sliding block on traversing guide；
X is set between two X-direction rail ends, is fixed in Installation cabinet housing by mounting plate to driving motor
Wall；X sets X to driving sector gear to driving motor output shaft；
Two drive shafts, both ends set X to sector gear respectively, and respectively with X from X to driving motor output shaft to driving sector
The the first sector gear engagement of wheel and X on driving screw rod；
Two Y-direction guide rails and thereon the first, second Y-direction sliding block, two Y-direction guide rail both ends are respectively arranged at two X to driving
X of two X on drive block and two X-direction guide rails on screw rod is on sliding block；
Y-direction driving mechanism, including,
Two Y-directions drive screw rod, are arranged in parallel in the two Y-directions guide rail side respectively；Y-direction driving screw rod one end sets the second sector
Gear；
Two Y-direction drive blocks are set on the Y-direction driving screw rod, with Y-direction driving wire rod thread cooperation；The Y-direction drive block and two
The first, second Y-direction sliding block connects on Y-direction guide rail；
First, second Y-direction driving motor is set to two Y-direction rail ends, is fixed on the installation by mounting plate
Cabinet encloser inner wall；First, second Y-direction driving motor output shaft sets the first, second Y-direction driving sector gear, first, second Y
The second sector gear engagement of two Y-directions driving screw rod one end is distinguished to driving sector gear；
First Z-direction mechanism, the first Y-direction sliding block being set on the Y-direction guide rail；Including,
First Z-direction fixed plate, horizontal arrangement, one side are connected to the first Y-direction sliding block on the Y-direction guide rail and described
Y-direction drives on screw rod on Y-direction drive block, three through-holes of interval setting along its length in the first Z-direction fixed plate；
Lifting frame, including,
Two guide rods are arranged in two through-holes for being located at two sides in the first Z-direction fixed plate；
Upper and lower connecting rod is connected to the upper and lower ends of two guide rod；
First Z-direction drives screw rod, is arranged in the first Z-direction fixed plate and is located in the middle through-hole, upper and lower side is connected to institute
State the middle part of upper and lower connecting rod；The worm gear being engaged with is set on first Z-direction driving screw rod；
First Z-direction driving motor is vertically arranged at side in the first Z-direction fixed plate,
Its output shaft end is set and the worm gear meshed gears；
Second Z-direction mechanism, the second Y-direction sliding block being set on the Y-direction guide rail；
Z-direction guide rail and its Z-direction sliding block, Z-direction guide rail are vertically arranged at the second Y-direction sliding block lateral surface and Y-direction driving silk
Two Y-direction drive block on bar；
Second Z-direction drives screw rod, is arranged in parallel in Z-direction guide rail side, the upper end sets transmission gear；
Z-direction drive block is set on the second Z-direction driving screw rod, with the driving wire rod thread cooperation of the second Z-direction；Z-direction driving
Block is connect with Z-direction sliding block on Z-direction guide rail；2nd Z driving motor is vertically arranged at the second Z-direction driving screw rod side,
Output shaft sets driving gear, and couples the transmission gear that second Z-direction drives screw rod upper end by synchronous belt；
First grabbing device, the second grabbing device are respectively arranged at the lifting frame and second of first Z-direction mechanism
On the Z-direction sliding block of Z-direction mechanism.
4. biological sample storage device as claimed in claim 3, which is characterized in that first grabbing device includes,
Screw rod is clamped, is arranged in parallel in by bracket below the lower link of first Z-direction mechanism lifting frame；
Two clamping jaws are set to the clamping screw rod, and cooperate with clamping wire rod thread；
First clamping motor, lower link one end of the lifting frame is vertically to by mounting plate, output shaft sets third umbrella shape
Gear, correspondingly, clamping screw rod one end sets the 4th bevel gear engaged with the third bevel gear.
5. biological sample storage device as claimed in claim 3, which is characterized in that the second grabbing device includes,
Fixing sleeve, one side are fixed on the Z-direction sliding block of second Z-direction mechanism, and fixing sleeve top bottom surface sets through-hole；
Rack gear is arranged in the fixing sleeve top bottom surface and sets through-hole；
Second clamping motor, is set to the fixing sleeve lateral surface, output shaft protrudes into fixing sleeve, and output shaft end is set and rack gear
Meshed gears；
Clamping piece is set to the rack gear lower end.
6. biological sample storage device as claimed in claim 3, which is characterized in that further include a sighting device, be set to
Z-direction rail back in second Z-direction mechanism.
7. biological sample storage device as described in claim 1, which is characterized in that the transferring box transmission mechanism, including,
Fixed pedestal is set in the Installation cabinet by liquid nitrogen container placing table, and corresponding Installation cabinet opening, fixed pedestal includes bottom plate
Both side plate and its fixed frame of front side；
Upper mounted plate is horizontally placed on lower part in the fixed pedestal, horizontal one fixed column of projection of front end face, the fixed column edge
Axially set through-hole；
Front door, its underpart are pivotally connected to the fixed column on front side of fixed plate, and size is matched with the fixed frame；
Preceding door drive mechanism, comprising:
Two screw rods, are horizontally placed on the fixed pedestal side plate lateral surface respectively, and the fixed bracket of screw both end is connected to described solid
Determine base side boards；The sliding block being threadedly engaged therewith is set on screw rod；
Two connecting rods, one end of two connecting rods are movably connected on two sliding block lateral surfaces on two screw rod, and the other end of two connecting rods is living
Dynamic to be connected to a connecting seat, which is connected to front door medial surface lower part two sides；
One driving device, couples described screw rod one end, which is connected on the fixed pedestal bottom plate by mounting base；
Transmission mechanism, including,
Two telescopic joints are horizontally placed on upper mounted plate both sides of the upper end in the fixed pedestal respectively, and each telescopic joint includes,
Mounting plate is horizontally placed on upper mounted plate both sides of the upper end in the fixed pedestal；
Fixed plate is slidably connected on the inside of the mounting plate；
Sliding panel is slidably connected on the inside of the fixed plate；
Two toothed racks, bottom surface are dentalation, are installed on the fixed plate bottom surface of described two telescopic joints；
Transferring box holds plate, and bottom surface both side is connected to the inside of described two telescopic joint sliding panels；
Two transmitting driving motors, are symmetrically disposed on the transferring box and hold board bottom Middle face two sides, transmit the defeated of driving motor
Shaft is vertical with rack axis, and output shaft end sets the gear being engaged with rack；Wherein a transmitting driving motor passes through installation
Bracket is connected to the transferring box and holds board bottom face, and another transmitting driving motor is connected to the fixed pedestal by mounting bracket
Bottom plate upper surface.
8. biological sample storage device as claimed in claim 7, which is characterized in that the driving device includes,
Driving motor is connected on the fixed pedestal bottom plate by mounting base, and motor output shaft end sets a bevel gear；
Two drive shafts are located at driving motor two sides, and the two sides of two drive shafts are fixed on the fixed pedestal bottom plate by support,
Drive shaft both ends set bevel gear, and the bevel gear of one end is engaged with driving motor output shaft end bevel gear；
Two connecting shafts, are vertically arranged at the other end of two drive shaft respectively, and the both ends of connecting shaft set bevel gear, one end
Bevel gear engaged with the bevel gear of drive shaft；Described screw rod one end sets bevel gear, the other end umbrella shape tooth of connecting shaft
Wheel is engaged with the bevel gear of screw rod one end；Driving motor drives drive shaft to drive the sliding block on screw rod by connecting shaft, screw rod
Mobile, the connecting rod for being connected to one end on sliding block pushes and pulls the front door, realizes open and close control.
9. biological sample storage device as claimed in claim 7, which is characterized in that further include a cap sheathing mechanism, be set to institute
Fixed pedestal upper end is stated, including,
Upper cover fixed frame, including two fixed links and connecting rod；Two fixed links are vertical with the fixed pedestal side plate, two fixed links
Medial surface sets guide groove along its length；
Upper cover door, two sides set link block, and the projection of link block lateral surface can be embedded at the two fixed links medial surface guide groove
Salient point；
Two upper covers fix bracket, U-shaped, are arranged in parallel in front of and after the upper cover fixed frame, the fixed bracket both ends difference of upper cover
It is connected to two fixed links；
First belt pulley is set to the fixed mid-stent of the upper cover before the upper cover fixed frame；
Upper cover driving motor, the fixed bracket of another upper cover after the bracket upper cover fixed frame is connected to by mounting plate
Middle part side, output shaft sets the second belt pulley, and couples the first belt pulley by driving belt；A connection is set on driving belt
Block connects upper cover door.
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| CN201820811684.7U CN208647604U (en) | 2018-05-29 | 2018-05-29 | A kind of biological sample storage device |
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| CN201820811684.7U CN208647604U (en) | 2018-05-29 | 2018-05-29 | A kind of biological sample storage device |
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| CN110547289A (en) * | 2019-07-29 | 2019-12-10 | 上海原能细胞生物低温设备有限公司 | Biological sample multifunctional workstation |
| CN110589332A (en) * | 2019-10-08 | 2019-12-20 | 苏州贝康医疗器械有限公司 | Automated biological sample library |
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| CN111903661B (en) * | 2019-05-08 | 2024-02-20 | 青岛海特生物医疗有限公司 | Liquid nitrogen storage device |
| CN111903661A (en) * | 2019-05-08 | 2020-11-10 | 青岛海特生物医疗有限公司 | Liquid nitrogen storage device |
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| CN110547289A (en) * | 2019-07-29 | 2019-12-10 | 上海原能细胞生物低温设备有限公司 | Biological sample multifunctional workstation |
| CN110547289B (en) * | 2019-07-29 | 2024-03-01 | 上海原能细胞生物低温设备有限公司 | Multifunctional workstation for biological samples |
| CN110589332A (en) * | 2019-10-08 | 2019-12-20 | 苏州贝康医疗器械有限公司 | Automated biological sample library |
| CN110589332B (en) * | 2019-10-08 | 2020-11-06 | 苏州贝康医疗器械有限公司 | Automated biological sample library |
| WO2021068373A1 (en) * | 2019-10-08 | 2021-04-15 | 苏州贝康医疗器械有限公司 | Automatic biological sample library |
| CN113120604A (en) * | 2019-12-30 | 2021-07-16 | 上海原能细胞生物低温设备有限公司 | Access pipe operating device |
| JP7431474B2 (en) | 2020-02-27 | 2024-02-15 | 上海原能▲細▼胞生物低温▲設▼▲備▼有限公司 | Low temperature storage retrieval equipment and low temperature storage retrieval method |
| WO2021169148A1 (en) * | 2020-02-27 | 2021-09-02 | 上海原能细胞生物低温设备有限公司 | Cryogenic storage and retrieval apparatus and cryogenic storage and retrieval method |
| CN115557242B (en) * | 2022-12-05 | 2023-03-03 | 基点生物科技(成都)有限公司 | Biological sample access device |
| CN115557242A (en) * | 2022-12-05 | 2023-01-03 | 基点生物科技(成都)有限公司 | Biological sample access device |
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