CN208611055U - A kind of lung therapeutic device - Google Patents

Abstract

The utility model discloses a kind of lung therapeutic devices, it is made of unidirectional valve, frame and the film layer covered on frame surface, the distal end of the frame and the proximal end of the frame include that an at least row crosses mast, every row mast that crosses includes that at least two groups cross mast, the outside of the joint of the mast intersected two-by-two in every group is known as vertex, and each vertex of the distal end of the frame is respectively formed on a positioning bulb；The distal end of the frame or the mast of proximal end are respectively formed tubular structure, a part of mast is greater than the diameter for the second tubular structure that mast described in another part is formed in the near proximal ends of the frame in the diameter of the first tubular structure of the proximate distal ends formation of the frame, some another mast connects the proximal end of the first tubular structure and the proximal end or middle part of the second tubular structure, and the mast of the part mast and the second tubular structure of formation is central axial least partially overlapped.

Description

A kind of lung therapeutic device

Technical field

The utility model relates to a kind of medical instruments, and in particular to the dress in a kind of interventional therapy for Patients with Lung treatment It sets, especially a kind of device for patient's tuberculosis treatment is particularly suitable for multi-drug resistance tuberculosis.

Background technique

Pulmonary tuberculosis is a kind of disease for seriously endangering human health, it is the pneumonia infection caused by mycobacterium tuberculosis Disease.Mycobacterium tuberculosis is in latence or persistent infection state after infecting human body mostly, it can be in infection host The intracellular defense reaction for escaping host to mass propagation and and host reach the delicate balance of one kind, the infected is in life Whenever it is likely to fall ill.Under normal circumstances, 10% the infected would develop into active tuberculosis.One untreated Active tuberculosis patient, 10-15 people can be infected within 1 year.

After antibiotic is by utility model and control theory lungy and technology, clinical conditions are horizontal It is universal due to effective chemotherapeutics (isoniazid, rifampin, pyrazinamide, streptomysin, ethambutol etc.) with the progress of research Using with BCG vaccine in worldwide popularization so that disease incidence lungy was once once reducing, so that people optimistically recognize For tuberculosis the same with smallpox will be utterly destroyed by the mankind.However global tuberculosis gets damp again comprehensively since the 1990s, sends out Sick rate is gone up again in worldwide, and WHO in 1993 announces that tuberculosis is in " global emergency state ", and appeals " rapidly It takes action and wages a struggle with tuberculosis crisis ".Drug resistance and multi-drug resistance tuberculosis are great in current Tuberculosis control work It threatens.Resistant tuberculosis refers to the intracorporal mycobacterium tuberculosis of tuberculosis patient to an a kind of line antituberculotic --- different cigarette Drug resistance occurs for hydrazine, rifampin, ethambutol, pyrazinamide and streptomysin.And multi-drug resistance tuberculosis then refers at least to different cigarette Hydrazine and rifampin while drug resistance.It is multi-drug resistant since the lethal effect of isoniazid and rifampicin against Mycobacterium mycobacteria is most strong Tuberculosis is a kind of even more serious drug resistance of tuberculosis type.

According to the statistics of the World Health Organization, tuberculosis is only after AIDS virus/AIDS, in the whole world by single biography Maximum killer caused by metachromia pathogen.For 2013, the whole world has 9,000,000 people to suffer from tuberculosis in 1 year, and 1,500,000 people are dead In the disease.It is counted according to another Chinese sick control centre's Tubercufosis control center, current China has more than 500,000,000 people and infected tuberculosis point Branch bacillus, there is 1,000,000 new cases every year, more than 54000 people because of tuberculosis death.China is in 2007~2008 in the whole nation The drug resistance of tuberculosis Baseline that range is carried out shows that multi-drug resistant rate is 8.32% in Chinese pulmonary tuberculosis patient, drug resistance Rate is 0.68%.It estimates accordingly, annual new hair more than 10 ten thousand people of Drug resistant pulmonary tubeculosis patient of China.

One of tuberculotherapy key points and difficulties be control again, refractory and Drug resistant pulmonary tubeculosis, thus to prevention lungy More acute challenge and higher requirement are proposed with treatment.It is right using conventional administration route (oral, intramuscular injection, intravenous) Multi-drug resistance tuberculosis patient carries out chemotherapy and has the following deficiencies: that 1. treatment cycle is long: a common tuberculosis patient, treatment cycle one As be 6 months；Multi-drug resistance tuberculosis people treatment cycle 18~24 months or even 36 months is 3~6 times of common tuberculosis patient； As one of most important Second line Drug, injection (such as kanamycins, capreomycin etc.) is using time at least six more than the moon. 2. therapeutic agent is more, adverse reaction rate is high: the first-line drug for treating common tuberculosis patient is about 4~5 kinds, adverse reaction Rate is not high；And at least 5~6 kinds of multi-drug resistance tuberculosis people therapeutic agent, and be the higher two wires antituberculotic of adverse reaction rate, Such as capreomycin, seromycin, protionamide etc..3. cure rate is low: currently, common tuberculosis patient cure rate mostly 85% with On, China is more than 90%；And the highest cure rate of multi-drug resistance tuberculosis people only has 50~60% or so；This means that existing Under the conditions of the multi-drug resistance tuberculosis people for having half is unable to get healing.

It is local fiber hyperblastosis, blood because most course of disease of multi-drug resistance tuberculosis patient is longer there are disadvantages described above For reduction, the osmotic absorption of drug is influenced, lesion is locally extremely difficult to kill the effective blood drug concentration of mycobacterium tuberculosis, so Conventional administration route (oral, intramuscular injection, intravenous) chemotherapy effect is poor, many years protracted course of disease, lung function progressive detraction, tuberculosis point Branch bacillus lasting masculin becomes lifelong excreter.Interventional therapeutic technique is the emerging therapeutic means that developed recently gets up, and is to control The multi-drug resistant phthisical effective means in cavity is treated, be applied to clinical and obtains certain curative effect.

The interventional therapy of pulmonary tuberculosis transtracheal bronchus approach, through Bronchofiberscope guide perfusion antituberculotic, method be After conventional Fibro-bronchoscopy test, insertion bronchoscope to target segmenta bronchopulmonalia is open, and seal wire, conduit are introduced under radioscopy and is inserted Enter in cavity, exit seal wire, keep the catheter injects a small amount of contrast agent, it was demonstrated that for target cavity, injects antituberculotic, have net Change cavity, promotes mycobacterium tuberculosis to turn out cloudy, the effect of void closing.However antituberculosis therapy is proved effective slowly, and tuberculous cavity is normal Often there are multiple fistula mouths to communicate with bronchus, the mycobacterium tuberculosis that do not turn out cloudy be easy through fistula mouth by bronchogenic spread to lung its Its region.

The interventional therapy of pulmonary tuberculosis percutaneous puncture, method are chest CT scans, determine the position in cavity, local infiltration anesthesia After puncture inserting needle, CT is swept again, determine puncture needle in cavity, suction cavity in sputum, then by antituberculotic injection cavity in. The current Major Clinical of this method is applied to be not suitable for the cavity that fiberbronchoscope or branchofiberoscope can not reach, but There are the risks of the complication after puncture such as pneumothorax.

To sum up, the interventional therapy of pulmonary tuberculosis transtracheal bronchus approach is just with the mode of intervention to pulmonary tuberculosis target cavity Conveying drug therapy is carried out, is practically without and achievees the effect that kill mycobacterium tuberculosis completely, there is the tuberculosis that do not turn out cloudy The risk that mycobacteria is further sent out；The interventional therapy of pulmonary tuberculosis percutaneous puncture, although having aspirated pulmonary tuberculosis target cavity in art Interior sputum, but the risk of mycobacterium tuberculosis remnants is remained, pneumothorax etc. is had existed simultaneously while in addition puncture The risk for sending out disease occurs.

Utility model content

The utility model provides a kind of lung therapeutic device, and placing in the bronchus of pulmonary tuberculosis target hole region proximal end should After lung therapeutic device, which can be fixedly positioning in bronchus；The lung therapeutic device has the function of one-way ventilating, The air in pulmonary tuberculosis target hole region can gradually be discharged, prevent the mycobacterium tuberculosis in pulmonary tuberculosis target cavity because anoxic from Breeding, so as to effectively limit or reduce the quantity of mycobacterium tuberculosis；Such as further cooperate drug therapy using the device, it can To improve the drug concentration in pulmonary tuberculosis target hole region, so that remaining mycobacterium tuberculosis is turned out cloudy, promote pulmonary tuberculosis target cavity Final closure；Or cooperate operative treatment using the device, the sputum in target cavity is pumped out, so that remaining tuberculosis branch Bacillus is destroyed completely, promotes the final closure in pulmonary tuberculosis target cavity；Also, the lung therapeutic device is curing pulmonary tuberculosis, is making lung After tuberculosis target void closing, it can be taken out by the common interventional operation equipment such as recover and recycling conduit.

The utility model provides a kind of lung therapeutic device, mainly by unidirectional valve, frame and covers on frame surface Film layer composition, the proximal end of the distal end of the frame and the frame include that an at least row crosses mast, and every row crosses mast packet It includes at least two groups to cross mast, the outside of the joint of the mast intersected two-by-two in every group is known as vertex, the distal end of the frame Each vertex be respectively formed on a positioning bulb；The distal end of the frame or the mast of proximal end are respectively formed tubular structure, and one The mast is divided to be greater than mast described in another part described in the diameter of the first tubular structure of the distal end of frame formation The diameter for the second tubular structure that the proximal end of frame is formed, some another mast connect the proximal end and second of the first tubular structure The proximal end or middle part of tubular structure, the part mast and form the mast of the second tubular structure at least portion on central axial Divide overlapping；The unidirectional valve is set in second tubular structure, and with cover the frame surface film layer progress Gluing is fixed.

Compared with prior art, the beneficial effects of the utility model are as follows:

The air in pulmonary tuberculosis target hole region can be gradually discharged in the lung therapeutic device of the utility model, so that pulmonary tuberculosis target Mycobacterium tuberculosis in cavity is because anoxic is irreproducible, so as to effectively limit or reduce the quantity of mycobacterium tuberculosis；Knot After composite medicine or operative treatment, pulmonary tuberculosis can be cured, make pulmonary tuberculosis target void closing.

Certainly, any product for implementing the utility model does not necessarily require achieving all the advantages described above at the same time.

Detailed description of the invention

Fig. 1 is the structural schematic diagram of the lung therapeutic device of the utility model embodiment 1；

Fig. 2 is that the lung therapeutic device of the utility model embodiment 1 is placed in intrabronchial schematic diagram；

Fig. 3 is the present invention looks up structural representation of the lung therapeutic device of the utility model embodiment 1；

Fig. 4 is the structure diagram of the lung therapeutic device of the utility model embodiment 1；

Fig. 5 is the structure diagram of the lung therapeutic device of the utility model embodiment 2；

Fig. 6 is that the lung therapeutic device of the utility model embodiment 2 is placed in intrabronchial schematic diagram；

Fig. 7 is the structure diagram of the lung therapeutic device of the utility model embodiment 3；

Fig. 8 is the structure diagram of the lung therapeutic device of the utility model embodiment 4；

Fig. 9 is the structure diagram of the lung therapeutic device of the utility model embodiment 5；

Figure 10 is the structure diagram of the lung therapeutic device of the utility model embodiment 6.

Specific embodiment

The utility model is further described below with specific embodiment.In the examples below, proximal end is lung Therapeutic device is close to one end of performer, distally one end for lung therapeutic device far from performer.

Embodiment 1

Fig. 1 is the side structure schematic diagram of the lung therapeutic device 1 of the utility model embodiment 1.

As it can be seen that the lung therapeutic device 1 is by unidirectional valve 10, frame 11 and covers film layer on 11 surface of frame in Fig. 1 12 compositions.

Wherein, frame 11 is to surround the two-part pipe formed around a central axis L by multiple a plurality of types of masts 113 The combination of the cone structure of two tubular structures of shape structure and connection；Wherein, frame 11 has proximal end 111, distal end 112, and A portion mast 113a is formed about the first tubular structure in the distal end of frame 11 112, and another part mast 113b is in frame The proximal end 111 of frame 11 is formed about the second tubular structure, and the cone structure is by connecting the proximal end and second of the first tubular structure Multiple mast 113c of the proximal end of tubular structure are formed.

In the structure of frame 11, the outside of the joint of the mast 113 intersected two-by-two is known as vertex 1131.

Wherein, the first tubular structure includes that two rows cross mast, and the first row close to distal end 112 includes 8 groups of columns that cross Bar, the second row far from distal end 112 include 4 groups of masts that cross, and the every group of mast that crosses includes two masts of intersection.First tubulose It is connected between the first row of structure crosses mast and second row crosses mast by vertex.

Second tubular structure includes that a row crosses mast.

Wherein, each vertex 1131 of the distal end 112 of frame 11 is respectively formed on a positioning bulb 1121 and (only shows in Fig. 1 Meaning property depicts a part positioning bulb).

As shown in Fig. 2, after the lung therapeutic device 1 for being provided with positioning bulb is placed in bronchus 2, the distal end 112 of frame 11 The mast 113a at place generates certain radial support power due to the pressure by bronchus 2, so that 1 energy of lung therapeutic device Strong fix is in bronchus 2；The frictional force of lung therapeutic device 1 Yu bronchus 2 can be increased by positioning bulb 1121 simultaneously, so that Lung therapeutic device 1 can be fixedly positioning in bronchus 2.

Simultaneously as 11 surface of frame is coated with the film layer 12 of isolation air circulation, and surrounded in multiple mast 113b The second tubular structure cavity in be arranged unidirectional valve 10, unidirectional valve 10 have by one-way ventilating function distally proximally Can, and proximate is isolation air-flow function, therefore the lung therapeutic device 1 can be formed to the unidirectional of pulmonary tuberculosis target hole region Circulation limitation, as shown in Fig. 2, air 3 enters less than in the pulmonary tuberculosis target hole region of 1 distal end of lung therapeutic device, while gas Pulmonary tuberculosis target hole region can be discharged by unidirectional valve 10 in body or sputum 4, reach the gas in pulmonary tuberculosis target cavity gradually Or the effect that sputum discharge is extraneous, so that mycobacterium tuberculosis in pulmonary tuberculosis target cavity is because anoxic is irreproducible, so as to have Effect limitation or the quantity for reducing mycobacterium tuberculosis.

The frame 11 of lung therapeutic device 1 is cut using tubing made of the elastic material with shape memory function through laser It is cut into the tubing with certain lines, and is strutted through mold and heat treatment shaping forms.Film layer 12 uses silicon rubber, poly- amino The high molecular materials such as formic acid esters, polyester or polytetrafluoroethylene (PTFE) are made, and take the techniques such as suture, bonding, dipping, spraying, thermal-adhering A tunic layer 12 is covered on 11 surface of frame and lung therapeutic device 1 can be made after unidirectional valve 10 is set.Above-mentioned moulding process and Coating technique is existing mature technology, and details are not described herein again.

Fig. 3 is the structural schematic diagram watched according to Fig. 1 of the present embodiment from proximal end 111 to 112 directions of distal end.Lung treatment The unidirectional valve 10 of device 1, frame 11 and the film layer 12 covered on 11 surface of frame are as shown in Figure 3.

It can be seen that first that a part of mast 113a is formed about in the distal end of frame 11 112 from Fig. 3 and in conjunction with Fig. 1 The diameter of tubular structure is greater than the second tubular structure that another part mast 113b is formed about in the proximal end of frame 11 111 Diameter.

Positioning bulb 1121 is formed in frame 11, at the vertex 1131 of distal end 112.

Meanwhile as can be seen from Figure 1, the second pipe near 11 proximal end 111 mast 113c Yu frame of the pyramidal structure of proximal end Projection of the mast 113b of shape structure on central axis L has overlapping, as shown in the sectional view of frame 11 in Fig. 4.Above-mentioned overlapping The mast 113a of structure design, the mast 113b and 11 distal end 112 of frame that are conducive to 11 proximal end 111 of frame during exercise can phase It is mutually independent, to will not interact when the oppressive forces such as being squeezed.

Unidirectional valve 10 is set to the inner hole that mast 113b is formed in the second tubular structure that the proximal end of frame 11 111 is formed In, and with cover 11 surface of frame film layer 12 carry out gluing fix.So set, being placed in bronchus in lung therapeutic device 1 After interior, the first tubular structure that the distal end 112 of frame 11 is formed generates certain radial support power due to being under pressure, thus It can enable 1 strong fix of lung therapeutic device in bronchus, while can guarantee unidirectional valve 10 in 111 shape of the proximal end of frame 11 At the second tubular structure in will not be squeezed power, avoiding being deformed causes to influence its one-way function.

Meanwhile positioning bulb 1121 can increase the frictional force of lung therapeutic device 1 Yu bronchus 2, so that lung treatment dress Setting 1 can fixedly positioning in bronchus.

Embodiment 2

Since the bronchus length having is shorter, therefore it is required that the axial length for being placed in bronchial lung therapeutic device is enough It is short.

In the structure of the frame 11a of the present embodiment, the outside of the joint of every group of mast 113 intersected two-by-two is known as pushing up Point 1131.

As shown in the sectional view of the frame 11a shown in fig. 5 of the present embodiment, the mast 113b of frame 11a proximal end 111a, frame The mast 113a of the distal end of frame 11 112, and its projection of the mast 113c on central axis L between the two have overlapping.

So set, can guarantee unidirectional valve 10 in the second tubular structure of the proximal end 111a formation of frame 11a not While will receive extruding force and be deformed influence, the length of instrument is effectively shortened.

After lung therapeutic device 1a is placed in bronchus 2, since length of the frame 11a on central axis L effectively subtracts It is short, therefore the proximal end 111a of frame 11a will not touch the inner wall of bronchus 2, as shown in fig. 6, to will not influence frame The one-way ventilating function of unidirectional valve 10 inside the proximal end 111a of 11a, therefore lung therapeutic device 1a can be formed to pulmonary tuberculosis The unidirectional through-flow limitation of target hole region.

Embodiment 3

Due to lung therapeutic device merging bronchus in after, need by frame distal end mast 113a radial support power into The firm fixation of row, therefore the more the quantity of the mast 113a of frame distal end the more firm, however after frame surface is covered with film layer 12, More mast 113a will increase the retraction volume of lung therapeutic device, and the thickness of film layer 12 is generally higher than 10 microns.This requires The mast 113a quantity of frame cannot be too many.

Fig. 7 is the structural schematic diagram of the frame 11b of embodiment according to the present utility model.Wherein, the proximal end of frame 11b 111b nearby includes that two rows cross mast 113b, is crossed mast as the dotted line frame in Fig. 7 show first row, and first row crosses column Bar 113b includes 4 groups of masts that cross in a circumferential direction, and it also includes 4 groups of masts that cross that second row, which crosses in mast 113b circumferential direction,； The distal end 112b of frame 11 nearby includes that three rows cross mast 113a, and proximally toward distal end number, first row crosses mast 113a weeks It upwards include 4 groups of masts that cross, second row and third arrange and respectively include 8 groups of masts that cross in the mast 113a circumferential direction that crosses.In addition, The proximal end of the first tubular structure near the distal end 112b of frame 11b and the proximal end of the second tubular structure near frame 11b The quantity of mast 113c between the distal end of 111b is 4.

Be designed in this way, it is ensured that in loading process, be arranged in the first tubular structure near the 112b of distal end proximal end and Mast 113c between the middle part of the second tubular structure near the proximal end 111b of frame 11b has the function of guiding.

Frame 11b uses silk material made of the elastic material with shape memory function, woven at network management, and loads Enter mold and heat treatment shaping is made；Frame 11b can also be using made of the elastic material with shape memory function Silk material works out forming directly on mold, and thermally treated sizing is made.Such moulding process is existing mature technology, herein It repeats no more.

Embodiment 4

Since the proximal end of frame had both been covered with film layer 12, it is additionally provided in the tubular structure that multiple masts of proximal end are formed unidirectional Flap valve 10, the leaflet of especially unidirectional valve 10 is arranged in the cavity of the second tubular structure of proximal end, and unidirectional valve 10 1 As be made of quantity greater than 2 leaflet, leaflet thickness is greater than 10 microns.Therefore it is required that the mast quantity foot that crosses of the proximal end of frame It is enough few.

Fig. 8 is the structural schematic diagram according to the frame 11c of the present embodiment.

The proximal end 111c of frame 11c is nearby made of the two rows mast 113b that crosses, and proximally toward distal end number, first row crosses It include 4 groups of masts that cross in mast 113b circumferential direction, it includes 8 groups of masts that cross in mast 113b circumferential direction that second row, which crosses,.

The distal end 112c of frame 11c is nearby made of the four rows mast 113a that crosses, and proximally toward distal end number, every row crosses column It include 8 groups of masts that cross in bar 113a circumferential direction.

It is attached for the proximal end of the first tubular structure near connection framework 11c distal end 112c and the proximal end 111c of frame 11c The quantity of mast 113c between the middle part of the second close tubular structure is 8, is designed in this way, it is ensured that in loading process, The mast 113c of the part has the function of guiding.Since frame 11c uses the elastic material system with shape memory function At, therefore it can be compressed the tubular structure for being less than 2.8mm for diameter, and is placed in bronchus by bronchoscope, load In the process, using the lung therapeutic device with the design structure, bronchoscope or other conveyings can be conveniently and effectively guided into In system.

Embodiment 5

After bronchus is built into the lung therapeutic device, in subsequent tuberculosis treatment, may also it need to pulmonary tuberculosis target Region carries out the treatment such as conveying drug or suction sputum bacteria, therefore it is required that the proximal end of the lung therapeutic device can be convenient for stretching through conduit simultaneously Enter conduit and reaches distal end.

Fig. 9 is according to the structural schematic diagram of the frame 11d of the present embodiment, and the proximal end 111d of frame 11d is nearby handed over by a row Converge mast 113b composition, it includes 4 groups of masts that cross in mast 113b circumferential direction which, which crosses, and the row mast 113b that crosses is formed by Tubular structure is conical pipe, and the diameter of the proximal end of the second tubular structure near the proximal end 111d of frame 11d is than frame 11d's The diameter of the distal end of the second tubular structure near the 111d of proximal end is big.It is designed in this way, it can be convenient after being placed in lung therapeutic device Subsequent conduit enters distal end by the proximal end of lung therapeutic device and carries out conveying drug or suction sputum bacteria etc. to pulmonary tuberculosis target region Treatment.

The distal end 112d of frame 11d is nearby made of the three rows mast 113a that crosses, and proximally toward distal end number, first row crosses It include 4 groups of masts that cross in mast 113a circumferential direction, it includes 8 groups of columns that cross in the mast 113a circumferential direction that crosses that second row and third, which are arranged, Bar.Connection is arranged near the proximal end of the first tubular structure near the distal end 112d of frame 11d and the proximal end 111d of frame 11d The second tubular structure distal end between mast 113c quantity be 4, be designed in this way, it is ensured that in loading process, should Partial mast has the function of guiding.

Embodiment 6

Positioning thorn 1122 is provided on outer surface near referring to Figure 10, the distal end 112e of the frame 11e of the present embodiment, Positioning thorn 1122 is made of thorn root 11221 and puncture tip 11222.Namely lung therapeutic device 1e's is initial pre- in its natural state It shapes under shape namely under opening state, the thorn root 11221 of positioning thorn 1122 proximally extends to distal end 112e and bends proximally 111e is arranged such positioning thorn 112e, may make the inclination of puncture tip 11222 to be directed toward the proximal end of lung therapeutic device 1e, such as Figure 10 institute Show.After bronchoscope or visual conduit are by the bronchus 2 of lung therapeutic device 1e merging pulmonary tuberculosis target hole region, positioning The puncture tip 11222 of thorn 1122 can penetrate the inner wall of bronchus 2, and the proximal end of lung therapeutic device 1e is directed toward in the inclination of puncture tip 11222 111e as shown in Figure 10, therefore can prevent lung therapeutic device 1e from proximally being shifted by the distal end of bronchus 2, so that lung is controlled Device 1e energy strong fix is treated in target bronchus 2.

After pulmonary tuberculosis is cured, if lung therapeutic device 1e need to be taken out, it can be recycled by recycling conduit and recover.It returns Under receipts state, positioning thorn 1122 can be transformed into compressive state with the compression of frame 11e, and the puncture tip 11222 of compressive state is bent And the distal end for being directed toward lung therapeutic device 1e is tilted, and the thorn root 11221 when compressive state remains unchanged in the close of positioning thorn 1122 End, such setting are to be conducive to positioning thorn 1122 to be compressed in the recycling conduit hence into proximal end.Therefore pass through recycling Conduit and recover can successfully take out lung therapeutic device 1e.

In addition to shown in above embodiments, positioning bulb also can be set on the vertex of the proximal end of every kind of frame, to realize The purpose for increasing friction, being fixedly secured.

To sum up, the lung therapeutic device of the utility model has a characteristic that

A, lung therapeutic device is made of unidirectional valve, frame and the film layer covered on frame surface, frame have proximal end, Distal end and central axis, and the tubular structure including being formed by mast, the first pipe that a part of mast is formed in the distal end of frame The diameter of shape structure is greater than the diameter for the second tubular structure that another part mast is formed in the proximal end of frame.In frame, two-by-two Outside at the joint of the mast of intersection is referred to as vertex.The wherein proximal end of the first tubular structure of connection framework proximate distal ends With the proximal end of the second tubular structure of frame proximal end attachment or a part of mast of centre and the mast of frame near proximal ends in Mandrel is least partially overlapped upwards.The apex that every group of mast of frame distal end crosses forms positioning bulb.Pass through frame distal end Mast formed radial support power and positioning bulb frictional force lung therapeutic device can be made to fixedly positioning in bronchus.It is single To flap valve be set to mast frame proximal end formed the second tubular structure in, and with cover frame surface film layer progress Gluing is fixed.Unidirectional valve has the function of the one-way ventilating of distal end proximally, and proximate is isolation air-flow function.

B, the quantity of the mast that crosses of frame distal end is greater than or equal to the mast quantity that crosses of frame proximal end.

D, frame distal end or frame proximal end include that an at least row crosses mast.

E, every row of frame distal end or frame proximal end mast that crosses includes that at least two groups cross mast.

F, the quantity of the group of the mast that crosses of the proximal end side of the first tubular structure of frame proximate distal ends, frame proximal end are attached The quantity of the group of the mast that crosses of the distal end side of the second close tubular structure and quantity positioned at above-mentioned mast between the two It is consistent with each other, it is designed in this way, it is ensured that in lung therapeutic device loading process, have the function of guiding.

G, the proximal end side of the first tubular structure of frame proximate distal ends group into the mast that crosses of distal end side respectively arranged Quantity it is consistent, or be in double increase.

H, the proximal end side of the second tubular structure of frame near proximal ends group into the pillar that crosses of distal end side respectively arranged Quantity it is consistent, or be in double increase.

I, the second tubular structure of frame near proximal ends is in bell-mouth structure of air, i.e. the second tubular structure proximal diameter is greater than remote Diameter is held, is designed in this way, subsequent conduit can be facilitated to enter by the proximal end of lung therapeutic device after being placed in lung therapeutic device Distal end carries out the treatment such as conveying drug or suction sputum bacteria to pulmonary tuberculosis target region.

J, leaflet of the unidirectional valve by quantity greater than 2 forms, and leaflet thickness is at 10 microns or more.

K, frame by nickel-titanium metal etc. there is the elastic material of shape memory function to be made.

L, by tubing, integrally cutting is made frame, and tubing thickness is in 0.1mm or more.

M, film layer and flap valve are good by biocompatibilities such as silicon rubber, polyurethanes, polyester or polytetrafluoroethylene (PTFE) High molecular material is made.

N, thicknesses of layers is at 10 microns or more.

The preferred embodiment in the utility model disclosed above is only intended to help to illustrate the utility model.Preferred embodiment is simultaneously There is no the details that detailed descriptionthe is all, also not limiting the utility model is only the specific embodiment.Obviously, according to this theory The content of bright book can make many modifications and variations.These embodiments are chosen and specifically described to this specification, is in order to preferably The principles of the present invention and practical application are explained, so that skilled artisan be enable to better understand and utilize this Utility model.The utility model is limited only by the claims and their full scope and equivalents.

Claims (10)

1. a kind of lung therapeutic device, which is characterized in that mainly by unidirectional valve, frame and cover film layer group on frame surface It include that an at least row crosses mast at, the proximal end of the distal end of the frame and the frame, every row mast that crosses includes at least The outside of two groups of masts that cross, the joint of the mast intersected in every group two-by-two is known as vertex, each of the distal end of the frame Vertex is respectively formed on a positioning bulb；The distal end of the frame or the mast of proximal end are respectively formed tubular structure, described in a part Mast is greater than mast described in another part in the frame in the diameter for the first tubular structure that the proximate distal ends of the frame are formed The diameter for the second tubular structure that the near proximal ends of frame are formed, some another mast connect the proximal end of first tubular structure With the proximal end or middle part of second tubular structure, the mast of the part mast and formation second tubular structure is in Mandrel is least partially overlapped upwards；The unidirectional valve is set in second tubular structure, and with cover in the frame The film layer on surface carries out gluing and fixes.

2. lung therapeutic device as described in claim 1, which is characterized in that the quantity of the mast that crosses of the distal end of the frame is big In or equal to the frame proximal end the mast quantity that crosses.

3. lung therapeutic device as described in claim 1, which is characterized in that the friendship of the proximal end of the first tubular structure of the frame Converge the quantity of mast, the frame the second tubular structure distal end or middle part the mast that crosses quantity and the use between them It is consistent in the quantity for the mast for connecting the rwo.

4. lung therapeutic device as described in claim 1, which is characterized in that the proximal end of the first tubular structure of the frame is to far The quantity of the group of the mast that crosses respectively arranged at end is consistent, or is in double increase.

5. lung therapeutic device as described in claim 1, which is characterized in that the proximal end of the second tubular structure of the frame is to far The quantity of the group of the pillar that crosses respectively arranged at end is consistent, or is in double increase.

6. lung therapeutic device as described in claim 1, which is characterized in that the second tubular structure of the proximal end of the frame is in loudspeaker Mouth structure, the i.e. diameter of the proximal end of the second tubular structure are greater than the diameter of its distal end.

7. lung therapeutic device as described in claim 1, which is characterized in that the unidirectional valve is by the good height of biocompatibility Molecular material is made, and leaflet of the unidirectional valve by quantity greater than 2 forms, and leaflet thickness is at 10 microns or more.

8. lung therapeutic device as described in claim 1, which is characterized in that be arranged on the outer surface of the proximate distal ends of the frame There is positioning to pierce, the positioning thorn is made of Ci Gen and puncture tip；Under the opening state of the lung therapeutic device, positioning thorn from The thorn root of proximal end is to distally extending and bend proximally.

9. lung therapeutic device as described in claim 1, which is characterized in that by tubing, integrally cutting is made the frame, described The thickness of tubing is in 0.1mm or more.

10. lung therapeutic device as described in claim 1, which is characterized in that the film layer is by the good high score of biocompatibility Sub- material is made, and the thicknesses of layers is at 10 microns or more.