CN208549709U - A kind of light induction experimental rat retina oxidativestress damage model equipment - Google Patents

A kind of light induction experimental rat retina oxidativestress damage model equipment Download PDF

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Publication number
CN208549709U
CN208549709U CN201821068693.8U CN201821068693U CN208549709U CN 208549709 U CN208549709 U CN 208549709U CN 201821068693 U CN201821068693 U CN 201821068693U CN 208549709 U CN208549709 U CN 208549709U
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CN
China
Prior art keywords
mouse
venetian blind
rearging cage
experimental rat
pedestal
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Expired - Fee Related
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CN201821068693.8U
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Chinese (zh)
Inventor
李红波
郝佳晖
张博
张一博
刘亚丽
葛宏选
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Xian Medical University
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Xian Medical University
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Priority to CN201821068693.8U priority Critical patent/CN208549709U/en
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Publication of CN208549709U publication Critical patent/CN208549709U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model discloses a kind of light induction experimental rat retina oxidativestress damage model equipments, including upper and lower top cover and pedestal disposed in parallel, four vertex of top cover and pedestal pass through telescopic rod respectively, it is horizontal between two neighboring telescopic rod to be equipped with venetian blind fixed link, venetian blind fixed link is located at the upper end of telescopic rod, and venetian blind fixed link is equipped with venetian blind, LED lamp tube and ventilation fan are respectively equipped on the inner surface of top cover, the inner surface of pedestal is equipped with the wooden box body of upper surface opening, and the mouse rearging cage of transparent material is equipped in wooden box body.Pass through the design of mirror surface and reflecting coating, it is ensured that model utmostly reduces illumination loss in relatively closed space, to increase the stability of light loss model.

Description

A kind of light induction experimental rat retina oxidativestress damage model equipment
Technical field
The utility model belongs to clinical medicine ophthalmology and basic medical research technical field, is related to a kind of light induction experiment With Rat retina oxidativestress damage model equipment.
Background technique
The research of light induction retina oxidativestress damage, and different pharmaceutical is anti-oxidant answers under the damaging action Sharp retina Protective effects research is always the hot and difficult issue of ophthalmology and base neural field of scientific study.Using not It is real both at home and abroad at present with the experimental provision of the vivo-induced experimental animal retina cell oxidativestress damage of white light of intensity Room and not formed unified production specification are tested, and there are intensities of illumination because of mouse feeding for experimental provision used in previous easy making Material, device itself block and the increase of the mouse eye closing frequency and time and weaken, air permeability is poor, later maintenance trouble etc. ask Topic is urgently improved.
Utility model content
The purpose of the utility model is to provide a kind of light induction experimental rat retina oxidativestress damage model equipment, Pass through the design of mirror surface and reflecting coating, it is ensured that model utmostly reduces illumination loss in relatively closed space, to increase The stability of light loss model is added.
The utility model is the technical scheme adopted is that a kind of light induction experimental rat retina oxidativestress damage mould Four vertex of type device, including top cover and pedestal disposed in parallel up and down, top cover and pedestal pass through telescopic rod respectively, adjacent Horizontal between two telescopic rods to be equipped with venetian blind fixed link, venetian blind fixed link is located at the upper end of telescopic rod, and venetian blind is fixed Bar is equipped with venetian blind, and LED lamp tube and ventilation fan are respectively equipped on the inner surface of top cover, and the inner surface of pedestal is spacious equipped with upper surface The wooden box body of mouth, the interior mouse rearging cage for being equipped with transparent material of wooden box body;
The surface of mouse rearging cage is arranged in LED lamp tube face.
One side A of wooden box body is openable and closable drop-down door, and the bottom of side A is connected by hinge and pedestal It connects.
The utility model is also characterized by
The maximal regulated height of venetian blind is the half of telescopic rod maximal regulated height.
The height of wooden box body is the half of telescopic rod maximal regulated height.
Four side walls of wooden box body and the inner surface of pedestal post mirror surface.
Part of the top cover inner surface in addition to LED lamp tube and ventilation fan has been coated with reflecting coating material.
Reflecting coating material has been coated on the inside of all blades of venetian blind.
The top of mouse rearging cage is uncovered structure, and wire netting A is equipped at the open top of mouse rearging cage, and mouse is raised The side for supporting cage is equipped with feed entrance, and feed inlet is equipped with wire netting B, and feed entrance is located at away from mouse rearging cage bottom At one third height, the side of mouse rearging cage setting feed entrance is additionally provided with glossy clear inclined plate, and the bottom of inclined plate is lucky It is overlapped with the bottom of feed entrance;The side of mouse rearging cage is additionally provided with water inlet, and water inlet and feed entrance are located at mouse feeding On the same side for supporting cage.
The beneficial effects of the utility model are as follows:
(1) present apparatus is using transparent mouse rearging cage and eliminating all pairs of illumination of traditional experiment mouse cage has what is blocked to feed Water feeding component, and reequiped on the outside of mouse cage, it effectively reduces device itself attachment and illumination is blocked, thus maximum journey Degree reduces the influence to device intensity of illumination;
(2) present apparatus is by being arranged mirror surface in four sides of wooden box body and base inner wall, in top cover inner wall and blinds Reflecting coating is set on the inside of the blade of window, it is ensured that the present apparatus utmostly reduces illumination loss in relatively closed space, thus Increase the stability of light loss model;
(3) present apparatus uses LED lamp tube, can reduce the fluorescent tube heat production in light loss experimentation inside device to the greatest extent, avoid Because long-time fluorescent tube is using heat production significant change occurs for device internal temperature;
(4) by carrying out independent switch control to each fluorescent tube, so that the luminous intensity adjustable range section of the device is larger, The packet design needs of various luminous intensities in light loss experimentation can be met.
Detailed description of the invention
Fig. 1 is that a kind of structure of light induction experimental rat retina oxidativestress damage model equipment of the utility model is shown It is intended to;
Fig. 2 is to remove top in a kind of light induction experimental rat retina oxidativestress damage model equipment of the utility model The structural schematic diagram of lid;
Fig. 3 is top cover in a kind of light induction experimental rat retina oxidativestress damage model equipment of the utility model Bottom view;
Fig. 4 is that mouse is raised in a kind of light induction experimental rat retina oxidativestress damage model equipment of the utility model Support the structural schematic diagram of cage.
In figure, 1. top covers, 2. pedestals, 3. telescopic rods, 4. venetian blind fixed links, 5. water inlets, 6. venetian blinds, 7.LED lamp Pipe, 8. ventilation fans;
9. wooden box body, the side 9-1. A;
10. mouse rearging cage, 11. wire netting A, 12. feed entrances, 13. wire netting B, 14. inclined plates, 15. side plates.
Specific embodiment
The utility model is described in detail with reference to the accompanying drawings and detailed description.
A kind of light induction experimental rat retina oxidativestress damage model equipment of the utility model, such as the institute of Fig. 1~3 Show, including top cover 1 and pedestal 2 disposed in parallel up and down, four vertex of top cover 1 and pedestal 2 pass through telescopic rod 3, phase respectively Horizontal between adjacent two telescopic rods 3 to be equipped with venetian blind fixed link 4, venetian blind fixed link 4 is located at the upper end of telescopic rod 3, and blinds Curtain fixed link 4 is equipped with venetian blind 6, is respectively equipped with several LED lamp tubes 7 and ventilation fan 8 on the inner surface of top cover 1, pedestal 2 it is interior Surface is equipped with the wooden box body 9 of upper surface opening, and the mouse rearging cage 10 of transparent material is equipped in wooden box body 9.1 pair of wood of top cover The upper port of matter box body 9 carries out all standing.Top cover 1 rear end face (define present apparatus face people side be front end face) be located at The venetian blind fixed link 4 of rear side is connected by hinge together, such connection type, when can make to open top cover 1 every time, upwards to After raise, and do not have to entire top cover 1 is taken off.
The surface of mouse rearging cage 10 is arranged in 7 face of LED lamp tube.It is arranged in parallel between each LED lamp tube 7, and each LED lamp tube 7 individually controls.The quantity of ventilation fan 8 accounts for a quarter area of 1 inner surface of top cover.On the inner wall of top cover 1, respectively Gap between the gap of LED lamp tube 7, each ventilation fan 8 has been coated with reflecting coating material.Each ventilation fan 8 is located in top cover 1 The same side of wall.
The maximal regulated height of venetian blind 6 is the half of 3 maximal regulated height of telescopic rod.
The height of wooden box body 9 is the half of 3 maximal regulated height of telescopic rod.
Four side walls of wooden box body 9 and the inner surface of pedestal 2 post mirror surface.
One side A9-1 of wooden box body 9 is openable and closable drop-down door, the bottom of side A9-1 by hinge with The pedestal 2 connects.
Reflecting coating material has been coated on the inside of all blades of venetian blind 6.
As shown in figure 4, the top of mouse rearging cage 10 is uncovered structure, and set at the open top of mouse rearging cage 10 There is wire netting A11, the side of mouse rearging cage 10 is equipped with feed entrance 12, is equipped with wire netting B13 at feed entrance 12, feed enters It (is highly mouse rearging cage 10 where feed entrance 12 that mouth 12, which is located at the one third height away from 10 bottom of mouse rearging cage, At the one third that side whole height rises from bottom to up), the side that feed entrance 12 is arranged in mouse rearging cage 10 is additionally provided with light Sliding transparent inclined plate 14, the both ends of inclined plate 14 pass through a side plate 15 respectively and connect with the two neighboring side of mouse rearging cage 10, The bottom of inclined plate 14 is overlapped with the bottom of feed entrance 12 just;The side of mouse rearging cage 10 is additionally provided with water inlet 5, water inlet Mouth 5 is located on the same side of mouse rearging cage 10 with feed entrance 12.Inclined plate 14 and horizontal plane angle be 30 °~ 40°。
When feeding water feeding to experimental rat, the sliding door of side A9-1 is pulled open, feed is under gravity along inclined plate 14 It voluntarily sliding to the wire netting B13 of feed entrance 12, mouse is fed by the network interface of wire netting B13, meanwhile, for being fed to mouse The water bottle metal mouth of water is downwardly at water inlet 5 along inclined plate 14, to meet the drinking-water demand of experimental rat.
A kind of the characteristics of light induction experimental rat retina oxidativestress damage model equipment of the utility model is,
(1) under the premise of avoiding heat production using LED lamp tube, reinforce ventilation using the design of ventilation fan and venetian blind, have Effect improves the gas permeability inside device, has thoroughly prevented experimental rat during light loss the phenomenon that death by suffocation;
(2) the energization facility inside the present apparatus includes that LED lamp tube, ventilation fan concentrate on top cover, it is ensured that circuit will not Also the facilitation during daily maintenance device is taken into account under the premise of being destroyed the safety interfered with mouse by raising experiment Operation such as feeds water to experimental rat, feeding is expected, wiping arrangement internal mirror and replacement fluorescent tube etc..
A kind of light induction experimental rat retina oxidativestress damage model equipment of the utility model, every time at most can be same The building for the experimental animal model that 6 rats of Shi Rongna are 1 group, to the building of mouse model because every raising box can accommodate 3-5 Mouse, therefore the building of 18-30 mouse light loss model can be carried out simultaneously.Light loss experiment starts front opening side A9-1's Lower sliding door takes out mouse rearging cage and experimental animal is respectively put into mouse rearging cage, by preprepared feed and gives Water bottle is placed on the inclined plate 14 of mouse rearging cage side.Then it is put into mouse rearging cage in order, shuts lower sliding door, according to pre- First pass through LED lamp tube required for the good required intensity of illumination of photometric determination is successively opened, and according to environment temperature and Humidity condition opens 1-3 ventilation fan, while light loss experiment starts timing.After the completion of setting the light loss time, ventilation is successively closed Fan and LED light open clamshell doors and take out the subsequent experimental operation that mouse rearging cage carries out experimental animal.

Claims (7)

1. a kind of light induction experimental rat retina oxidativestress damage model equipment, it is characterised in that: including parallel up and down Four vertex of the top cover (1) and pedestal (2) of setting, top cover (1) and pedestal (2) pass through telescopic rod (3) respectively, two neighboring Horizontal between telescopic rod (3) to be equipped with venetian blind fixed link (4), venetian blind fixed link (4) is located at the upper end of telescopic rod (3), and hundred Leaf curtain fixed link (4) is equipped with venetian blind (6), is respectively equipped with LED lamp tube (7) and ventilation fan (8) on the inner surface of top cover (1), The inner surface of pedestal (2) is equipped with the wooden box body (9) of upper surface opening, and the mouse equipped with transparent material is raised in wooden box body (9) It supports cage (10);
Surface of LED lamp tube (7) the face setting in mouse rearging cage (10);
One side A (9-1) of the wooden box body (9) is openable and closable drop-down door, and the bottom of side A (9-1) passes through Hinge is connect with the pedestal (2).
2. a kind of light induction experimental rat retina oxidativestress damage model equipment according to claim 1, special Sign is: the maximal regulated height of the venetian blind (6) is the half of the telescopic rod (3) maximal regulated height.
3. a kind of light induction experimental rat retina oxidativestress damage model equipment according to claim 1, special Sign is: the height of the wooden box body (9) is the half of the telescopic rod (3) maximal regulated height.
4. a kind of light induction experimental rat retina oxidativestress damage model equipment according to claim 1 or 3, Be characterized in that: four side walls of the wooden box body (9) and the inner surface of pedestal (2) post mirror surface.
5. a kind of light induction experimental rat retina oxidativestress damage model equipment according to claim 1, special Sign is: part of top cover (1) inner surface in addition to LED lamp tube (7) and ventilation fan (8) has been coated with reflecting coating material Material.
6. a kind of light induction experimental rat retina oxidativestress damage model equipment according to claim 1, special Sign is: being coated with reflecting coating material on the inside of all blades of the venetian blind (6).
7. a kind of light induction experimental rat retina oxidativestress damage model equipment according to claim 1, special Sign is: the top of the mouse rearging cage (10) is uncovered structure, and iron is equipped at the open top of mouse rearging cage (10) The side of silk screen A (11), mouse rearging cage (10) are equipped with feed entrance (12), are equipped with wire netting B (13) at feed entrance (12), Feed entrance (12) is located at the one third height away from mouse rearging cage (10) bottom, and mouse rearging cage (10) setting feed enters The side of mouth (12) is additionally provided with glossy clear inclined plate (14), and the bottom of inclined plate (14) is just heavy with the bottom of feed entrance (12) It closes;The side of mouse rearging cage (10) is additionally provided with water inlet (5), and water inlet (5) and feed entrance (12) are located at mouse rearging cage (10) on same side.
CN201821068693.8U 2018-07-06 2018-07-06 A kind of light induction experimental rat retina oxidativestress damage model equipment Expired - Fee Related CN208549709U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201821068693.8U CN208549709U (en) 2018-07-06 2018-07-06 A kind of light induction experimental rat retina oxidativestress damage model equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201821068693.8U CN208549709U (en) 2018-07-06 2018-07-06 A kind of light induction experimental rat retina oxidativestress damage model equipment

Publications (1)

Publication Number Publication Date
CN208549709U true CN208549709U (en) 2019-03-01

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Application Number Title Priority Date Filing Date
CN201821068693.8U Expired - Fee Related CN208549709U (en) 2018-07-06 2018-07-06 A kind of light induction experimental rat retina oxidativestress damage model equipment

Country Status (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113841621A (en) * 2021-09-28 2021-12-28 上海市第一人民医院 Experimental blue light-induced retinal light injury model device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113841621A (en) * 2021-09-28 2021-12-28 上海市第一人民医院 Experimental blue light-induced retinal light injury model device

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20190301

Termination date: 20210706