CN208454858U - A kind of polypeptide preparing mechanism and polypeptide preparation system - Google Patents

A kind of polypeptide preparing mechanism and polypeptide preparation system Download PDF

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Publication number
CN208454858U
CN208454858U CN201820948043.6U CN201820948043U CN208454858U CN 208454858 U CN208454858 U CN 208454858U CN 201820948043 U CN201820948043 U CN 201820948043U CN 208454858 U CN208454858 U CN 208454858U
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filter
polypeptide
connect
conveyance conduit
holding vessel
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CN201820948043.6U
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闫祥生
陈栋梁
成静
王勇
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TIANTIANHAO BIOLOGICAL PRODUCTS CO Ltd WUHAN CITY
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TIANTIANHAO BIOLOGICAL PRODUCTS CO Ltd WUHAN CITY
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Abstract

The utility model provides a kind of polypeptide preparing mechanism and polypeptide preparation system, belongs to active ingredient of natural product filtering purification technique field.It includes blending tank, holding vessel, filter assemblies, drier, inspissator and reflux line;Blending tank is connect with holding vessel, and filter assemblies are connect with holding vessel, and filter assemblies can carry out contaminant filter to polypeptide;Drier, inspissator are connect with filter assemblies respectively;The both ends of reflux line are connect with holding vessel, filter assemblies respectively, and reflux line can will be delivered in holding vessel by filtered polypeptide enzymolysis liquid and carry out circulating filtration.The first conveyance conduit is connected between blending tank and holding vessel, the first conveyance conduit is connected with the first centrifugal pump.The polypeptide preparation system has above-mentioned polypeptide preparing mechanism, and structure is simple and filter effect is good.

Description

A kind of polypeptide preparing mechanism and polypeptide preparation system
Technical field
The utility model relates to active ingredient of natural product filtering purification technique field more particularly to a kind of polypeptide draft machines Structure and polypeptide preparation system.
Background technique
Peptide (peptide) is a-amino acid with the compound that peptide bond links together and is formed, it is also protein hydrolysis Intermediate product.The number of the amino acid contained in general peptide is two to nine, and according to the difference of the quantity of amino acid in peptide, peptide has A variety of different addresses: the compound as made of two amino acid molecular dehydrating condensations is called dipeptides, similarly analogize there are also tripeptides, Tetrapeptide, pentapeptide etc., until nonapeptide.Usually the compound as made of 10~100 amino acid molecular dehydrating condensations is peptide material. Wherein, peptide material can be with the dirty middle extraction of driven sundries.And a step particularly critical in extraction process be the dirty freeze-thaw of animal device or Filtering after hydrolysis.In existing biochemical pharmacy technology, the driven dirty middle process for extracting peptide material of sundries is as follows: " initial medium (animal device is dirty) collection → clean stripping → colloid mill → freeze-thaw or hydrolysis → centrifugation or paper pulp, filter cloth, sedimentation → Hollow-fibre membrane ultrafiltration ".
However, the equipment that current polypeptide raw material uses when filtering, essentially one layer filtering, while device internal structure letter It is single, it can only accomplish simple filtering function, details can not be improved.
Utility model content
One of the purpose of this utility model is to provide a kind of polypeptide preparing mechanism, this polypeptide preparing mechanism aims to solve the problem that existing There is the problem of polypeptide filter plant poor filtration effect in technology;
The another object of the utility model is to provide a kind of polypeptide preparation system, this polypeptide preparation system aims to solve the problem that existing The problem for having the polypeptide filter plant filter efficiency in technology low.
To achieve the above object, the technical solution of the utility model is:
A kind of polypeptide preparing mechanism, the polypeptide preparing mechanism includes blending tank, holding vessel, filter assemblies, drier, dense Contracting device and reflux line;
The blending tank is connect with the holding vessel, and the filter assemblies are connect with the holding vessel, the filter assemblies Contaminant filter can be carried out to polypeptide;
The drier, the inspissator are connect with the filter assemblies respectively;
The both ends of the reflux line are connect with the holding vessel, the filter assemblies respectively, and the reflux line can It will be delivered in the holding vessel by filtered polypeptide and carry out circulating filtration.
As a kind of optimal technical scheme of the utility model, first is connected between the blending tank and the holding vessel Conveyance conduit, first conveyance conduit are connected with the first centrifugal pump.
As a kind of optimal technical scheme of the utility model, the filter assemblies include the second conveyance conduit, second from Heart pump, filter, medium tank, third conveyance conduit and third centrifugal pump;The both ends of second conveyance conduit respectively with institute Holding vessel, filter connection are stated, second centrifugal pump is connect with second conveyance conduit;The third conveyance conduit Both ends connect respectively with the filter, the medium tank, the third centrifugal pump is connect with the third conveyance conduit.
As a kind of optimal technical scheme of the utility model, tee tube is installed at the top of the filter, described three Siphunculus has the first connector and the second connector, and first connector is connect with the third conveyance conduit, and described second For connector for installing air pressure pump, the air pressure pump can exclude the air in the filter.
As a kind of optimal technical scheme of the utility model, tee tube, the tee tube are installed on the filter With the first connector and the second connector, first connector is connect with the third conveyance conduit, second connection Mouth is connected with warm-air drier, and the warm-air drier is for being passed through hot-air into the filter.
As a kind of optimal technical scheme of the utility model, the bottom of the filter offers impurities outlet, described Sealing cover is installed, the sealing cover can turn on or off the impurities outlet on impurities outlet.
As a kind of optimal technical scheme of the utility model, the drier includes the 4th centrifugal pump, the first connecting tube Road, air blower, case ontology and the second connecting pipe;The both ends of first connecting pipe respectively with the filter assemblies, institute The connection of case ontology is stated, the 4th centrifugal pump is connect with first connecting pipe, the both ends difference of second connecting pipe It is connect with the case ontology, the air blower;It is disposed with active carbon particle layer and activity from the bottom to top in the case ontology Carbon fibe layer.
As a kind of optimal technical scheme of the utility model, it is defeated that the inspissator with the filter assemblies is connected with the 4th Pipeline is sent, the 4th conveyance conduit is connected with the 5th centrifugal pump.
As a kind of optimal technical scheme of the utility model, the 6th centrifugal pump is installed on the reflux line.
A kind of polypeptide preparation system, the polypeptide preparation system include above-described polypeptide preparing mechanism.
The beneficial effects of the utility model are:
The utility model provides a kind of polypeptide preparing mechanism by above-mentioned design, and the polypeptide preparing mechanism is due to having mixing Tank, holding vessel, filter assemblies, drier, inspissator and reflux line;Wherein, blending tank is connect with holding vessel, filter assemblies It is connect with holding vessel, filter assemblies can carry out contaminant filter to polypeptide, and filter assemblies include the second conveyance conduit, the second centrifugation Pump, filter, medium tank, third conveyance conduit and third centrifugal pump;The both ends of second conveyance conduit respectively with holding vessel, mistake Filter connection, the second centrifugal pump are connect with the second conveyance conduit;The both ends of third conveyance conduit connect with filter, medium tank respectively It connects, third centrifugal pump is connect with third conveyance conduit, and tee tube is equipped at the top of filter, and tee tube has the first connector With the second connector, the first connector is connect with third conveyance conduit, and the second connector is for installing air pressure pump or warming up Blower, air pressure pump can exclude the air in filter, and warm-air drier can be to the delivered inside hot-air of filter;Cause This can exclude the air in filter, and then increase filter during filtering to polypeptide by air pressure pump The volume of internal filtered fluid, effectively increases filter efficiency;Also, during cleaning filter interior, warm wind can be passed through Filter medium on the lamination of the hot-air drying filter of compression is facilitated shaking off for filter residue by machine;Meanwhile in the process of filtering In, the medium in medium tank can be added in filter, increase filter effect, it can be effective by the impurity in polypeptide enzymolysis liquid Removal.Simultaneously as the both ends of the second connecting pipe are connect with case ontology, air blower respectively, setting in the case ontology of drier Therefore active charcoal stratum granulosum and activated carbon fiber layers when filter is stopped using, can effectively ensure that filter Internal relatively dry environment prolongs its service life so that filter is not easy to be corroded.Further, since filtering Reflux line is connected between device and holding vessel, therefore, the polypeptide enzymolysis liquid after filtering by first time can be again by Reflux line flows back into holding vessel, and then secondary cycle filters, so that the filter effect of polypeptide is more preferable.Secondly as Filter is connected with inspissator, and therefore, the polypeptide after circulating filtration, which is able to enter in inspissator, carries out concentration technology, Obtain the finished product polypeptide for meeting product requirement.It follows that the polypeptide preparing mechanism has structurally reasonable and filter effect good Feature.
The utility model provides a kind of polypeptide preparation system by above-mentioned design, the polypeptide preparation system due to having more than Polypeptide preparing mechanism therefore have the characteristics that structure is simple and easy to use.
Detailed description of the invention
It, below will be to required in embodiment in order to illustrate more clearly of the technical solution of the utility model embodiment The attached drawing used is briefly described, it should be understood that the following drawings illustrates only some embodiments of the utility model, therefore not It should be considered as the restriction to range, for those of ordinary skill in the art, without creative efforts, It can also be obtained according to these attached drawings other relevant attached drawings.
Fig. 1 is polypeptide preparing mechanism structural schematic diagram provided by the embodiment of the utility model;
Fig. 2 is filter assemblies structural schematic diagram provided by the embodiment of the utility model;
Fig. 3 is dryer configuration schematic diagram provided by the embodiment of the utility model;
Fig. 4 is filter assemblies provided by the embodiment of the utility model and inspissator attachment structure schematic diagram.
Icon: 1- polypeptide preparing mechanism;2- blending tank;3- holding vessel;4- filter assemblies;5- drier;6- inspissator;7- Reflux line;The first conveyance conduit of 8-;The first centrifugal pump of 9-;The second conveyance conduit of 10-;The second centrifugal pump of 11-;12- filter; 13- medium tank;14- third conveyance conduit;15- third centrifugal pump;16- tee tube;18- impurities outlet;The 4th centrifugal pump of 19-; The first connecting pipe of 20-;21- air blower;22- case ontology;The second connecting pipe of 23-;The 4th conveyance conduit of 24-;25- the 5th from Heart pump;The 6th centrifugal pump of 26-.
Specific embodiment
It is practical new below in conjunction with this to keep the objectives, technical solutions, and advantages of the embodiments of the present invention clearer Attached drawing in type embodiment, the technical scheme in the utility model embodiment is clearly and completely described, it is clear that is retouched The embodiment stated is the utility model a part of the embodiment, instead of all the embodiments.Usually here in attached drawing description and The component of the utility model embodiment shown can be arranged and be designed with a variety of different configurations.
Therefore, requirement is not intended to limit to the detailed description of the embodiments of the present invention provided in the accompanying drawings below The scope of the utility model of protection, but it is merely representative of the selected embodiment of the utility model.Based in the utility model Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all Belong to the range of the utility model protection.
It should also be noted that similar label and letter indicate similar terms in following attached drawing, therefore, once a certain Xiang Yi It is defined in a attached drawing, does not then need that it is further defined and explained in subsequent attached drawing.
In the description of the present invention, it should be noted that the orientation or positional relationship of the instructions such as term " on ", "lower" For be based on the orientation or positional relationship shown in the drawings or the utility model product using when the orientation or position usually put Relationship is merely for convenience of describing the present invention and simplifying the description, rather than the device or element of indication or suggestion meaning must There must be specific orientation, be constructed and operated in a specific orientation, therefore should not be understood as limiting the present invention.
In addition, in the present invention unless specifically defined or limited otherwise, fisrt feature on second feature or Under may include that the first and second features directly contact, may include the first and second features be not direct contact but logical yet Cross the other characterisation contact between them.Moreover, fisrt feature is on second feature, top and above include fisrt feature Right above second feature and oblique upper, or first feature horizontal height is merely representative of higher than second feature.Fisrt feature is Under two features, lower section and fisrt feature included below be directly below and diagonally below the second feature, or be merely representative of fisrt feature Level height is less than second feature.
In addition, the terms such as term "horizontal", "vertical" are not offered as requiring component abswolute level or pendency, but can be slightly Low dip.It is not to indicate that the structure has been had to if "horizontal" only refers to that its direction is more horizontal with respect to for "vertical" It is complete horizontal, but can be slightly tilted.
In the description of the present invention, it should also be noted that, unless otherwise clearly defined and limited, term " is set Set ", " connected ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integrally Connection;It can be mechanical connection, be also possible to be electrically connected;Can be directly connected, can also indirectly connected through an intermediary, It can be the connection inside two elements.For the ordinary skill in the art, above-mentioned art can be understood with concrete condition The concrete meaning of language in the present invention.
Embodiment:
Fig. 1 is please referred to, referring to Figure 2 to Figure 4, the present embodiment provides a kind of polypeptide preparation systems comprising polypeptide system for cooperation Standby host structure 1, the polypeptide preparing mechanism 1 are filtered polypeptide enzymolysis liquid for making polypeptide, finally obtain polypeptide at Product.
Please refer to Fig. 1 to Fig. 4, polypeptide preparing mechanism 1 includes blending tank 2, holding vessel 3, filter assemblies 4, drier 5, dense Contracting device 6 and reflux line 7;Blending tank 2 is connect with holding vessel 3, and filter assemblies 4 are connect with holding vessel 3, and filter assemblies 4 can Contaminant filter is carried out to polypeptide;Drier 5, inspissator 6 are connect with filter assemblies 4 respectively;The both ends of reflux line 7 respectively with storage Tank 3, the connection of filter assemblies 4 are deposited, reflux line 7 can will be delivered in holding vessel 3 by filtered polypeptide and be circulated throughout Filter.
Further, in the present embodiment, the first conveyance conduit 8 is connected between blending tank 2 and holding vessel 3, first is defeated Pipeline 8 is sent to be connected with the first centrifugal pump 9, the first centrifugal pump 9 is used to the polypeptide enzymolysis liquid made in blending tank 2 being transported to storage It deposits and is stored in tank 3.
Wherein, filter assemblies 4 include the second conveyance conduit 10, the second centrifugal pump 11, filter 12, medium tank 13, third Conveyance conduit 14 and third centrifugal pump 15;The both ends of second conveyance conduit 10 are connect with holding vessel 3, filter 12 respectively, the Two centrifugal pumps 11 are connect with the second conveyance conduit 10;The both ends of third conveyance conduit 14 connect with filter 12, medium tank 13 respectively It connects, third centrifugal pump 15 is connect with third conveyance conduit 14;Second centrifugal pump 11 is used for the polypeptidase that will be stored in holding vessel 3 Solution liquid, which is transported in filter 12, is filtered operation.
It should be noted that in the present embodiment, the top of filter 12 is equipped with tee tube 16, and tee tube 16 has the One connector and the second connector, the first connector are connect with third conveyance conduit 14, and the second connector can install air pressure Contracting pump or warm-air drier;Wherein, air pressure pump can exclude the air in filter 12, and warm-air drier is then used for filter Hot-air is passed through in 12.
Therefore, it during being filtered to polypeptide enzymolysis liquid, can be excluded by air pressure pump in filter 12 Air, and then increase the volume of the filtered fluid inside filter 12, effectively increase filter efficiency;Also, in cleaning filter 12 In internal process, the hot-air of compression can be dried up to the filter medium on the lamination of filter 12 by warm-air drier, facilitate filter Slag is shaken off;Meanwhile during the filtration process, the medium in medium tank 13 can be added in filter 12, increases filter effect, Impurity in polypeptide enzymolysis liquid can effectively be removed.
It should be noted that in the present embodiment, the bottom of filter 12 offers impurities outlet 18, on impurities outlet 18 Sealing cover is installed, sealing cover can turn on or off impurities outlet 18, and the impurity filtered out from polypeptide enzymolysis liquid can It is discharged from the impurities outlet 18.
Wherein, drier 5 includes the 4th centrifugal pump 19, the first connecting pipe 20, air blower 21, case ontology 22 and second Connecting pipe 23;The both ends of first connecting pipe 20 are connect with filter assemblies 4, case ontology 22 respectively, the 4th centrifugal pump 19 and The connection of one connecting pipe 20, the both ends of the second connecting pipe 23 are connect with case ontology 22, air blower 21 respectively;In case ontology 22 by Under supreme be disposed with active carbon particle layer and activated carbon fiber layers.It therefore, can be when filter 12 be stopped using It waits, can effectively ensure that the relatively dry environment inside filter 12 prolongs so that filter 12 is not easy to be corroded Its long service life.
It should be noted that in the present embodiment, inspissator 6 and filter assemblies 4 are connected with the 4th conveyance conduit 24, the 4th Conveyance conduit 24 is connected with the 5th centrifugal pump 25, and the 5th centrifugal pump 25 can will be transported to inspissator 6 by the polypeptide of filtering Middle carry out concentration operation, finally obtains polypeptide finished product.
It should be noted that in the present embodiment, the 6th centrifugal pump 26 is equipped on reflux line 7, by the 6th from Polypeptide enzymolysis liquid after filtering for the first time can be again fed in holding vessel 3 by heart pump 26, and the is then carried out to it Secondary cycle filtering, improves its filter effect.
In conclusion the polypeptide preparing mechanism 1 is due to blending tank 2, holding vessel 3, filter assemblies 4, drier 5, dense Contracting device 6 and reflux line 7;Wherein, blending tank 2 is connect with holding vessel 3, and filter assemblies 4 are connect with holding vessel 3, filter assemblies 4 Contaminant filter can be carried out to polypeptide, filter assemblies 4 include the second conveyance conduit 10, the second centrifugal pump 11, filter 12, medium Tank 13, third conveyance conduit 14 and third centrifugal pump 15;The both ends of second conveyance conduit 10 respectively with holding vessel 3, filter 12 connections, the second centrifugal pump 11 are connect with the second conveyance conduit 10;The both ends of third conveyance conduit 14 respectively with filter 12, be situated between Matter tank 13 connects, and third centrifugal pump 15 is connect with third conveyance conduit 14, and the top of filter 12 is equipped with tee tube 16, threeway Pipe 16 has the first connector and the second connector, and the first connector is connect with third conveyance conduit 14, and the second connector is used for Installation air pressure pump or warm-air drier, air pressure pump can exclude the air in filter 12, and warm-air drier can be to filtering The delivered inside hot-air of device 12;Therefore, during filtering to polypeptide, filter can be excluded by air pressure pump Air in 12, and then increase the volume of the filtered fluid inside filter 12, effectively increase filter efficiency;Also, it was cleaning During 12 inside of filter, the hot-air of compression can be dried up to the filter medium on the lamination of filter 12 by warm-air drier, Facilitate shaking off for filter residue;Meanwhile during the filtration process, the medium in medium tank 13 can be added in filter 12, was increased Effect is filtered, the impurity in polypeptide enzymolysis liquid can effectively be removed.Simultaneously as the both ends of the second connecting pipe 23 respectively with Case ontology 22, air blower 21 connect, and are provided with active carbon particle layer and activated carbon fiber layers in the case ontology 22 of drier 5, because This, can effectively ensure that the relatively dry environment inside filter 12 when filter 12 is stopped using, So that filter 12 is not easy to be corroded, prolong its service life.Further, since connecting between filter 12 and holding vessel 3 It is connected to reflux line 7, therefore, the polypeptide enzymolysis liquid after filtering by first time can be flowed back into again by reflux line 7 In holding vessel 3, and then secondary cycle filters, so that the filter effect of polypeptide is more preferable.Secondly as filter 12 is connected with Inspissator 6, therefore, the polypeptide after circulating filtration, which is able to enter in inspissator 6, carries out concentration technology, obtains meeting production The finished product polypeptide that product require.It follows that the polypeptide preparing mechanism 1 has the characteristics that structurally reasonable and filter effect is good.This is more Peptide preparation system due to the polypeptide preparing mechanism 1 more than having, have the characteristics that structure is simple and easy to use.
The above descriptions are merely preferred embodiments of the present invention, is not intended to limit the utility model, for this For the technical staff in field, various modifications and changes may be made to the present invention.It is all in the spirit and principles of the utility model Within, any modification, equivalent replacement, improvement and so on should be included within the scope of protection of this utility model.

Claims (10)

1. a kind of polypeptide preparing mechanism, it is characterised in that: the polypeptide preparing mechanism include blending tank, holding vessel, filter assemblies, Drier, inspissator and reflux line;
The blending tank is connect with the holding vessel, and the filter assemblies are connect with the holding vessel, and the filter assemblies can Contaminant filter is carried out to polypeptide;
The drier, the inspissator are connect with the filter assemblies respectively;
The both ends of the reflux line are connect with the holding vessel, the filter assemblies respectively, and the reflux line can will be through It crosses filtered polypeptide and is delivered in the holding vessel and carry out circulating filtration.
2. polypeptide preparing mechanism according to claim 1, it is characterised in that: connect between the blending tank and the holding vessel It is connected to the first conveyance conduit, first conveyance conduit is connected with the first centrifugal pump.
3. polypeptide preparing mechanism according to claim 1, it is characterised in that: the filter assemblies include the second delivery pipe Road, the second centrifugal pump, filter, medium tank, third conveyance conduit and third centrifugal pump;The both ends of second conveyance conduit It is connect respectively with the holding vessel, the filter, second centrifugal pump is connect with second conveyance conduit;The third The both ends of conveyance conduit are connect with the filter, the medium tank respectively, the third centrifugal pump and the third delivery pipe Road connection.
4. polypeptide preparing mechanism according to claim 3, it is characterised in that: be equipped with tee tube, institute on the filter Tee tube is stated with the first connector and the second connector, first connector is connect with the third conveyance conduit, described For second connector for installing air pressure pump, the air pressure pump can exclude the air in the filter.
5. polypeptide preparing mechanism according to claim 3, it is characterised in that: be equipped with tee tube, institute on the filter Tee tube is stated with the first connector and the second connector, first connector is connect with the third conveyance conduit, described Second connector is connected with warm-air drier, and the warm-air drier is for being passed through hot-air into the filter.
6. polypeptide preparing mechanism according to claim 3, it is characterised in that: the bottom of the filter offers impurity and goes out Mouthful, sealing cover is installed on the impurities outlet, the sealing cover can turn on or off the impurities outlet.
7. polypeptide preparing mechanism according to claim 1, it is characterised in that: the drier includes the 4th centrifugal pump, the One connecting pipe, air blower, case ontology and the second connecting pipe;The both ends of first connecting pipe respectively with the filtering Component, case ontology connection, the 4th centrifugal pump are connect with first connecting pipe, and the two of second connecting pipe End is connect with the case ontology, the air blower respectively;It is disposed with active carbon particle layer from the bottom to top in the case ontology And activated carbon fiber layers.
8. polypeptide preparing mechanism according to claim 1, it is characterised in that: the inspissator is connect with the filter assemblies There is the 4th conveyance conduit, the 4th conveyance conduit is connected with the 5th centrifugal pump.
9. polypeptide preparing mechanism according to claim 1, it is characterised in that: be equipped with the 6th centrifugation on the reflux line Pump.
10. a kind of polypeptide preparation system, it is characterised in that: the polypeptide preparation system includes described in any one of claim 1 to 9 Polypeptide preparing mechanism.
CN201820948043.6U 2018-06-19 2018-06-19 A kind of polypeptide preparing mechanism and polypeptide preparation system Active CN208454858U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111500438A (en) * 2020-06-10 2020-08-07 扬州润明智能装备股份有限公司 Vinasse polypeptide extraction equipment and extraction method
CN115074409A (en) * 2022-08-18 2022-09-20 意润健康产业(广州)有限公司 Micromolecule active peptide separation and purification system based on organic animal and plant raw materials

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111500438A (en) * 2020-06-10 2020-08-07 扬州润明智能装备股份有限公司 Vinasse polypeptide extraction equipment and extraction method
CN115074409A (en) * 2022-08-18 2022-09-20 意润健康产业(广州)有限公司 Micromolecule active peptide separation and purification system based on organic animal and plant raw materials

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