Heating device for gas filter system
Technical field
The utility model relates to a kind of heating devices, in particular to a kind of heating device for gas filter system.
Background technique
Disposable flexibly foster bag is used on bioreactor more and more, can be put in culture bag gas outlet position
Pneumatic filter is set to prevent external environment to polluting in bag, meanwhile, the gas warp with certain temperature and moisture in bag
Outside pneumatic filter output bag.Disposable bioreactor operating ambient temperature is generally below 30 DEG C, in the workshop GMP use condition
Under, ambient temperature range is 18~26 DEG C, and the considerations of in terms of cost, disposable bioreactor can also be commonly without sky
It is used in the laboratory of tune condition, such ambient temperature range just becomes larger, and generally 5~30 DEG C, this is just to culture bag outlet
The pneumatic filter of mouth position is put forward higher requirements, therefore, to assure that gas smooth output in pneumatic filter, no steam are solidifying
Tie phenomenon.The gas flow rate range in culture bag is output and input generally in 50~1000ml/min, when flow velocity is higher not only compared with
Culture bag heat is taken away fastly, increases temperature reduction amplitude in culture bag, and also brings along unnecessary gas waste, it is practical
Generally using compared with low flow velocity in work.It is lower than " dew-point temperature " hereinafter, when gas flow rate is slower, in gas in operating ambient temperature
Steam can inside pneumatic filter the long period delay, and be finally condensed into water droplet, block filter opening, influence gas filtration
The service efficiency of device can increase heating device in the external of pneumatic filter, make steam temperature and work to improve this situation
Make environment temperature and keep smaller difference, prevents steam in pneumatic filter condensation arising inside water with this.
Distinguished according to structure type, the heating device of pneumatic filter can be divided into it is open and closed, it is as shown in Figure 1
Open heating method is to directly adopt heating component to heat pneumatic filter, is frame mode the most succinct,
But heat loss is larger, efficiency is lower;Closed heating method is to increase shell in heating unit device exterior to be sealed, Ke Yiyou
Effect improves the thermal efficiency.But existing closed heating device is semi-enclosed heating (as shown in Figure 2), such as Patent No.:
The Chinese utility model patent of CN105579111 discloses a kind of filter heater, the heating method of the heater
Deficiency is that it is the heating for pneumatic filter, rather than entire filtration system.Therefore under low temperature tick-over environment,
Intratracheally it also will appear condensed water phenomenon outside pneumatic filter, condensed water can flow backward in pneumatic filter, make gas mistake
The blocking of filter inner air vent, reduces the service efficiency of pneumatic filter.In addition, this heating method in structure type there is also
Deficiency, highly cannot achieve adjusting, not be able to satisfy the demand of different volumes culture bag, and use the complex mechanisms such as spring.
Utility model content
The purpose of the utility model is to overcome existing pneumatic filters using caused by open and semi-enclosed structure
The problem of heat waste is big, low efficiency, provides a kind of new heating device for gas filter system, it is heated with totally enclosed type
The characteristics of.
To achieve the above object, it is used for the heating device of gas filter system designed by the utility model, including is used for
The shell for wrapping up the gas filter system, the heating sheet being disposed in the housing and on shell for adjusting its height
Bracket;The top and bottom of the shell, which are equipped with, holds the through-hole that the pipeline of the gas filter system passes through, when gas filtration system
When system is placed in shell, shell is in full closeding state;The shell includes abutting against and detachable left shell portion and right shell body
Portion;The bracket is connect by rotating mechanism with the shell;The heating sheet is electrically connected by power supply line with external power supply.
Further, the bracket and rotating mechanism it is each there are two, one of bracket pass through a rotating mechanism and institute
The connection of left shell portion is stated, another bracket is connect by another rotating mechanism with the right shell body portion.
Still further, the gas filter system include pneumatic filter, set on described pneumatic filter one end into
Tracheae, the escape pipe set on the pneumatic filter other end and the gas stop valve on the escape pipe.
Preferably, the heating sheet at least there are two, the inner walls set on the correspondence pneumatic filter position.
Further, the rotating mechanism includes two shafts and two knobs;The shaft is equipped with external screw thread, and shaft
One end is fixed with the shell, and the shaft other end is set to the hull outside and is cooperated by external screw thread and the knob thread;
The pedestal upper end is arranged or hook is located in shaft and is flexibly connected with shaft.
Preferably, washer is also arranged in the shaft.By the effect of washer, it may make that knob is tighter by bracket fixation
Gu.
Further, the bearing surface in the left shell portion and the right shell body portion is equipped with the fastener mutually fastened.Pass through card
The effect of fastener makes left shell portion and right shell body portion that can quickly split and splice merging, and use is more convenient, and structure is simple, at
This is low.
Further preferably, the heating sheet is silica-gel electrothermic silk heating sheet.
Preferably, the bracket is flexible metallic support, and outer wall packet is equipped with plastic layer or rubber layer.
Optionally, the housing sidewall is equipped with the electric wire opening passed through for power supply line.
The beneficial effects of the utility model are: by using by the totally enclosed structure type of gas filter system, i.e. shell
Pneumatic filter is not only encased, but also encases air inlet pipe, escape pipe and gas stop valve, is reduced inside and outside gas filter system
The difference of gas temperature makes gas that can not occur condensing phenomenon in entire gas filter system, not only ensure that in gas
The smooth discharge of steam, and the phenomenon that prevent low temperature low velocity gas to generate condensed water in gas filter system again, it ensure that
Pneumatic filter normally uses function, has also widened the use environment of disposable bioreactor;Pass through the work of rotating mechanism
With making bottom and disposable flexibly foster bag intimate surface contact and the adjustable support height of bracket, meet different volumes
The demand of culture bag.
Detailed description of the invention
Fig. 1 is structural schematic diagram when open heating device uses in the prior art.
Fig. 2 is structural schematic diagram when semi-enclosed heating device uses in the prior art.
Fig. 3 is structural schematic diagram when heating device of the utility model for gas filter system uses.
Enlarged structure schematic diagram of the Fig. 4 for shell in Fig. 3 after separated.
Fig. 5 is to remove the enlarged structure schematic diagram after culture bag in Fig. 3.
Fig. 6 is the structural schematic diagram in left shell portion in Fig. 5.
Fig. 7 is the structural schematic diagram in right shell body portion in Fig. 5.
Fig. 8 is to remove the structural schematic diagram after heating device in Fig. 4.
In figure, 1. shells;1.1. left shell portion;1.2. right shell body portion;2. heating sheet;3. gas filter system;3.1. gas
Body filter;3.2. air inlet pipe;3.3. escape pipe;3.4. gas stop valve;3.5. intermediate plate;4. bracket;5. rotating mechanism;5.1.
Shaft;5.2. knob;6. power supply line;7. ring portion;8. culture bag;9. fastener;10. through-hole.
Specific embodiment
The utility model is described in further detail below in conjunction with the drawings and specific embodiments.
The heating device for gas filter system as shown in figure 3 to figure 7, including for wrapping up gas filter system 3
Shell 1, the heating sheet 2 in shell 1 and the bracket 4 for being used to adjust its height on shell 1;The upper end of shell 1 is under
End, which is equipped with, holds the through-hole 10 that the pipeline of gas filter system 3 passes through, and when gas filter system 3 is placed in shell 1, shell 1 is in
Full closeding state;Shell 1 includes abutting against and detachable left shell portion 1.1 and right shell body portion 1.2;Bracket 4 passes through whirler
Structure 5 is connect with shell 1;Heating sheet 2 is electrically connected by power supply line 6 with external power supply (not shown).Gas filtration as shown in Figure 8
System 3 include pneumatic filter 3.1, set on 3.1 one end of pneumatic filter air inlet pipe 3.2, be set to pneumatic filter 3.1 it is another
The escape pipe 3.3 at end and the gas stop valve 3.4 on escape pipe 3.3.Certainly, gas filter system 3 can also include using
In the rigid plastics intermediate plate 3.5 for clamping air inlet pipe 3.2.
There are two bracket 4 and rotating mechanism 5 are each, one of bracket 4 passes through a rotating mechanism 5 and left shell portion 1.1
Connection, another bracket 4 are connect by another rotating mechanism 5 with right shell body portion 1.2.One rotating mechanism 5 includes two and turns
Axis 5.1 and two knobs 5.2;Shaft 5.1 is equipped with external screw thread, and 5.1 one end of shaft and shell 1 are fixed, 5.1 other end of shaft
It with knob 5.2 is threadedly engaged set on 1 outside of shell and by external screw thread;4 upper end of bracket is arranged or hook is located in shaft 5.1 and with
Shaft 5.1 is flexibly connected, i.e. the settable hook portion in 4 upper end of bracket or ring portion 7, if hook portion then its be hooked in shaft 5.1, and if
Ring portion 7 is then sheathed in shaft 5.1 (on condition that first backing out the knob 5.2 in shaft 5.1) from 5.1 outer end of shaft.When bracket 4
After upper end is set in shaft 5.1, knob 5.2 is twisted in shaft 5.1 and tightening, so that 4 upper end of bracket is screwed 5.2 and is clamped in
1 outer wall of shell, and before bracket 4 is fixedly clamped, its angle can be adjusted by runing rest 4, to change 4 bearing height of bracket
Then heating device height is influenced, so that heating device can be adapted for the demand of different volumes culture bag 8.In shaft 5.1 also
Washer (not shown) can be arranged.By the effect of washer, knob 5.2 may make more to fasten the fixation of bracket 4.
The bearing surface in left shell portion 1.1 and right shell body portion 1.2 is equipped with the fastener 9 mutually fastened, and fastener 9 may include one
The box and pin of fixed number amount is respectively arranged on left shell portion 1.1 and right shell body portion 1.2.By the effect of fastener 9, make left shell portion
1.1 and right shell body portion 1.2 can quickly split and splice merging, use is more convenient, and structure is simple, at low cost.Relative to background
The structure for the filter heater mentioned in technology is simpler.
1 inner wall of shell there are two heating sheet 2 is preferably at least, set on corresponding 3.1 position of pneumatic filter.Heating sheet 2
It can be silica-gel electrothermic silk heating sheet 2.Bracket 4 is flexible metallic support 4, and outer wall packet is equipped with plastic layer or rubber layer, is led to
It crosses plastic layer or rubber layer can increase stiction between bracket 4 and disposable flexibly foster bag 8, effectively prevent sliding relatively
It is dynamic.Bracket 4 is flexible but not to be soft, with certain hardness, can at least support entire heating device and indeformable
Or deformation quantity is smaller.1 side wall of shell can be equipped with the electric wire opening passed through for power supply line 6, quantity and add that specific electric wire is open
2 quantity of backing is corresponding, i.e., each corresponding electric wire opening of heating sheet 2.
In use, heating device is coated on outside the included gas filter system 3 in disposable 8 upper surface of flexibly foster bag
Portion;That is, separation left shell portion 1.1 and right shell body portion 1.2, by the pneumatic filter 3.1 of gas filter system 3, air inlet pipe 3.2,
Escape pipe 3.3 and gas stop valve 3.4 are all placed between left shell portion 1.1 and right shell body portion 1.2, then remerge left shell portion
1.1 with right shell body portion 1.2, and it is fixed by fastener 9.And it is directed to different disposable flexibly foster bags 8, by unscrewing knob
5.2, so that bracket 4 5.1 can turn an angle around the shaft, so as to adjust 4 height of bracket, tightened again after being adjusted to proper height
Knob 5.2 can fix bracket 4.After connecting external power supply, heating sheet 2 is powered to totally-enclosed to carrying out inside entire shell 1
Formula heating, entire gas filter system 3 are heated.
Fluid temperature in disposable flexibly foster bag 8 is 37 ± 0.2 DEG C, and gas temperature is 30 ± 5 DEG C in bag, gas in bag
Body relative humidity is 80 ± 5%RH, under certain pressure effect, by the gas with certain temperature and humidity through gas filtration system
Unite outside 3 output bags, if bag external environment temperature is lower and bag in gas output speed it is relatively slow in the case where, gas can be caused in gas mistake
Condensation, the condensed water condensed in pneumatic filter 3.1 can directly block the filter membrane of pneumatic filter 3.1 in filter system 3, go out
The condensed water condensed in tracheae 3.3 and gas stop valve 3.4 will flow back and deposit inside pneumatic filter 3.1, block gas
3.1 filter membrane of filter, can not work normally pneumatic filter 3.1, and the condensed water condensed in air inlet pipe 3.2 will form air film
Block bottom caliber.Therefore the heating device of the utility model reduces gas by the way of integral coating gas filter system 3
The difference of gas temperature inside and outside body filtration system 3 makes gas that can not occur condensing phenomenon in entire gas filter system 3.
In order to disclose the actual effect of utility model, under the same conditions to three kinds of different heatings as shown in Figure 1, 2, 3
Structure type compares experiment, is open heating, semi-enclosed heating and totally enclosed type heating respectively.Low velocity gas stream
Speed is set as 50ml/min, and gas relative humidity is 80 ± 5%RH.T1 is operating ambient temperature, and T2 is 3.1 table of pneumatic filter
Face temperature, T3 are gas temperature in culture bag 8, and T4 is gas temperature in gas stop valve 3.4, and each testing time is 1 small
When, every kind of test is repeated 5 times, and is then averaged.Test result is as follows:
Test result is shown, firstly, gas temperature and work in working environment in 25 DEG C or more and gas filter system 3
When making environment temperature difference less than 4 DEG C, i.e. when temperature gap between T4 and T1 is less than 4 DEG C, three kinds of heating methods can be prevented
Only condensed water occurs inside gas filter system 3;Secondly, open and two kinds semi-enclosed, gas filtration system
When gas temperature and operating ambient temperature in system 3 differ 4 DEG C or more, i.e. temperature gap between T4 and T1 is greater than 4 DEG C or more
When, it may appear that condensed water, and with the reduction of operating ambient temperature, condensed water phenomenon is more obvious;And in totally enclosed type,
Even if that is, in the lower situation of T1 temperature, the gas temperature difference is less than 1 inside and outside gas filter system 3 under lower working environment problem
DEG C, i.e. when temperature gap between T4 and T2 is less than 1 DEG C, also evaporated condensation water occurs, and shows totally enclosed type heating structure not by outer
Boundary's temperature influences, and can still guarantee that pneumatic filter 3.1 continues to work normally under low temperature low speed environments.From experimental result also into
One step proves that the heating device using totally enclosed type heating structure of the utility model can effectively avoid low temperature low velocity gas in gas
The phenomenon that condensed water is generated in body filtration system 3.