CN208327879U - Feline panleukopenia treatment single-chain antibody semifinished product precipitation separation device - Google Patents

Abstract

The utility model discloses feline panleukopenia treatment single-chain antibody semifinished product precipitation separation devices, including pressurizing tank, booster pump is fixedly connected at the top of the pressurizing tank, and inlet tube is communicated on the right side of pressurizing tank, and check valve is fixedly connected on inlet tube, the bottom of the pressurization box cavity is fixedly connected with pressurization vortex device, being pressurized vortex device includes vortex feed liquor block, the side wall of vortex feed liquor block offers inlet opening, motor casing is fixedly connected at the top of vortex feed liquor block, it is vortexed the top of feed liquor block and is fixedly connected with rotary electric machine positioned at the inside of motor casing, the utility model relates to pharmaceutical technology fields.Feline panleukopenia treatment single-chain antibody semifinished product precipitation separation device, inlet tube is flowed into the antibody mixing liquid come to be easier to filter after booster pump and pressurization vortex device, so that mixing liquid passes through the polymer matrix cover efficiency inside separator faster, separative efficiency is improved.

Description

Feline panleukopenia treatment single-chain antibody semifinished product precipitation separation device

Technical field

The utility model relates to pharmaceutical technology fields, specially feline panleukopenia treatment single-chain antibody semifinished product Precipitation separation device.

Background technique

Medicine is to struggle and salubrious science about the mankind with disease, its object is the people of society, therefore, doctor Learning has substantial connection with social science, Medicine Ethics, and this century, the famous western Gus of Biography of Medical Figures scholar refered in particular to out: medicine is one Social science, each action of medicine are related to two class parties always -- doctor and patient, or be medicine group more broadly Body and society, medicine is various relationships between this two crowds of people nothing but, development and medical model due to medical science Transformation, people are most of all over the world from traditional biomedical model to biology, psychology, Social Medicine Mode change As orthodox medicine, also referred to as general medical, general medical science, current medicine are all regarded modern Western medicine in countries and regions, or main Medicine is flowed, the medicine except doctor trained in Western medicine is then referred to as non-mainstream medicine, alternative medicine, complementary medicine, alternative medicine, unconventional medicine Deng medicine is divided into two parts: a part is basis, is bioscience；Another part of medicine is even more important and the master of medicine Body --- clinical medicine, medical domain has risen new disciplines: evidence-based medicine EBM in recent ten years, be exactly sufficiently seek it is believable Clinical evidence is also not enough to illustrate many problems because we depend these evidences that laboratory is drawn alone.

Existing antibody semifinished product precipitation separation device, uses centrifugation tank arrangement mostly, antibody protein is separated Out, but this mode separative efficiency higher cost that is lower, and using, operation is not convenient enough when separate type, makes score The antibody protein purity separated out is lower.

Utility model content

In view of the deficiencies of the prior art, it is crude to provide feline panleukopenia treatment single-chain antibody for the utility model Product precipitation separation device, it is lower to solve the centrifugal separation separative efficiency that existing separator uses, and lock out operation Inconvenient problem.

In order to achieve the above object, the utility model is achieved by the following technical programs: feline panleukopenia is controlled It treats and uses single-chain antibody semifinished product precipitation separation device, including pressurizing tank, be fixedly connected with booster pump at the top of the pressurizing tank, and It is communicated with inlet tube on the right side of pressurizing tank, and is fixedly connected with check valve on inlet tube, the bottom of the pressurization box cavity is fixed It is connected with pressurization vortex device, the pressurization vortex device includes vortex feed liquor block, and the side wall of the vortex feed liquor block offers Inlet opening, and be vortexed at the top of feed liquor block and be fixedly connected with motor casing, the top of the vortex feed liquor block and is located at motor casing Inside is fixedly connected with rotary electric machine, and the two sides of the pressurizing tank bottom are fixedly connected with support fixed plate, and support fixed plate Bottom be fixedly connected with fixed plate, the bottom of the pressurizing tank and bottom for being located at pressurization vortex device is communicated with separation dress It sets, the bottom of the separator is connected by the screw top of sealing nut and fixed plate.

Preferably, the separator includes pressurization cylinder, and the top of the pressurization cylinder is connected with the bottom of pressurizing tank, and The inner wall of pressurization cylinder is fixedly connected with fixed saturating plate, and the top of the saturating plate of fixation is rotatably connected to rotation axis by bearing.

Preferably, the top of the rotation axis is fixedly connected with one end of rotary electric machine output shaft, the table of the rotation axis Face is fixedly connected with rotation pressurization spiral plate.

Preferably, the bottom of the fixed plate and be located at pressurization cylinder bottom be fixedly connected with fixed thread pipe, it is described solid Determine to be connected with sealing rubber pad between the top of screwed pipe and the bottom of pressurization cylinder.

Preferably, the inner wall of the pressurization cylinder bottom is fixedly connected with retainer ring, and the inside of the pressurization cylinder and being located at is fixed The basal sliding of saturating plate is connected with polymer matrix cover.

Preferably, antibody diversion pipe is communicated between two pressurization cylinders, and antibody diversion pipe is far from separator One end runs through fixed plate and extends to the bottom of fixed plate, is fixedly connected with antibody diaphragm valve on the antibody diversion pipe, described One end that antibody diversion pipe is located at fixed plate bottom is communicated with flow guiding head, the bottom of the fixed plate and is located at separator just Lower section is communicated with separating tube.

Beneficial effect

The utility model provides feline panleukopenia treatment single-chain antibody semifinished product precipitation separation device.Have Below the utility model has the advantages that

(1), feline panleukopenia treatment single-chain antibody semifinished product precipitation separation device, by separator Including pressurization cylinder, the top of pressurization cylinder is connected with the bottom of pressurizing tank, and the inner wall of pressurization cylinder is fixedly connected with fixed saturating plate, The top of fixed saturating plate is rotatably connected to rotation axis by bearing, and the top of rotation axis and one end of rotary electric machine output shaft are fixed Connection, the surface of rotation axis are fixedly connected with rotation pressurization spiral plate, and inlet tube is flowed into the antibody mixing liquid come by increasing It is easier to filter after press pump and pressurization vortex device, so that mixing liquid passes through the polymer matrix cover effect inside separator Rate faster, improves separative efficiency, increases factory's benefit.

(2), feline panleukopenia treatment single-chain antibody semifinished product precipitation separation device, by fixed plate Bottom and be located at pressurization cylinder bottom be fixedly connected with fixed thread pipe, between the top of fixed thread pipe and the bottom of pressurization cylinder It is connected with sealing rubber pad, structure is simple, so that the easier operation of staff, so that production efficiency greatly improves, Separator can be sealed with fixed plate by sealing rubber pad and sealing nut tighter.

Detailed description of the invention

Fig. 1 is the structural schematic diagram of the utility model；

Fig. 2 is the schematic diagram that the utility model is pressurized vortex device structure；

Fig. 3 is the schematic diagram of the utility model separator structure.

In figure: 1- pressurizing tank, 2- booster pump, 3- pressurization vortex device, 31- vortex feed liquor block, 32- motor casing, 33- rotation Motor, 34- inlet opening, 4- inlet tube, 5- check valve, 6- support fixed plate, 7- fixed plate, 8- separator, 81- retainer ring, 82- Fixed saturating plate, 83- polymer matrix cover, 84- rotation axis, 85- rotation pressurization spiral plate, 86- pressurization cylinder, 9- antibody water conservancy diversion Pipe, 10- flow guiding head, 11- separating tube, 12- sealing nut, 13- antibody diaphragm valve, 14- fixed thread pipe, 15- sealing rubber pad.

Specific embodiment

The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work Every other embodiment obtained, fall within the protection scope of the utility model.

Fig. 1-3 is please referred to, the utility model provides a kind of technical solution: single-chain antibody is used in feline panleukopenia treatment Semifinished product precipitation separation device, including pressurizing tank 1, the top of pressurizing tank 1 are fixedly connected with booster pump 2, and the right side of pressurizing tank 1 It is communicated with inlet tube 4, and is fixedly connected with check valve 5 on inlet tube 4, the bottom of 1 inner cavity of pressurizing tank is fixedly connected with pressurization whirlpool Device 3 is flowed, pressurization vortex device 3 includes vortex feed liquor block 31, and the side wall of vortex feed liquor block 31 offers inlet opening 34, and is vortexed The top of feed liquor block 31 is fixedly connected with motor casing 32, is vortexed the top of feed liquor block 31 and is located at the fixed company in inside of motor casing 32 It is connected to rotary electric machine 33, rotation axis 84 can be driven to rotate rapidly by rotating electric machine 33, quick start, so that charging efficiency mentions Height, the two sides of 1 bottom of pressurizing tank are fixedly connected with support fixed plate 6, and the bottom of fixed plate 6 is supported to be fixedly connected with fixed plate 7, the bottom of the pressurizing tank 1 and bottom for being located at pressurization vortex device 3 is communicated with separator 8, the bottom of separator 8 passes through close Envelope nut 12 is connect with the screw top of fixed plate 7, and separator 8 includes pressurization cylinder 86, the top of pressurization cylinder 86 and pressurizing tank 1 Bottom be connected, and the inner wall of pressurization cylinder 86 is fixedly connected with fixed saturating plate 82, and the top of fixed saturating plate 82 passes through bearing and turns It is dynamic to be connected with rotation axis 84, inlet tube 4 is flowed into the antibody mixing liquid come after booster pump 2 and pressurization vortex device 3 more It is easy filtering, so that mixing liquid passes through 83 efficiency of polymer matrix cover inside separator 8 faster, improves separation effect Rate increases factory's benefit, and the top of rotation axis 84 is fixedly connected with one end of 33 output shaft of rotary electric machine, the table of rotation axis 84 Face be fixedly connected with rotation pressurization spiral plate 85, the bottom of fixed plate 7 and be located at pressurization cylinder 86 bottom be fixedly connected with fixation Screwed pipe 14 is connected with sealing rubber pad 15, pressurization cylinder between the top of fixed thread pipe 14 and the bottom of pressurization cylinder 86 The inner wall of 86 bottoms is fixedly connected with retainer ring 81, is easier pressurization cylinder 86 being installed to fixed thread pipe 14 by retainer ring 81, increase The inside of pressure cylinder 86 and the basal sliding for being located at fixed saturating plate 82 are connected with polymer matrix cover 83, between two pressurization cylinders 86 It is communicated with antibody diversion pipe 9, and the one end of antibody diversion pipe 9 far from separator 8 through fixed plate 7 and extends to fixed plate 7 Bottom, antibody diaphragm valve 13 is fixedly connected on antibody diversion pipe 9, one end that antibody diversion pipe 9 is located at 7 bottom of fixed plate connects It is connected with flow guiding head 10, the bottom of the fixed plate 7 and underface for being located at separator 8 is communicated with separating tube 11, structure is simple, so that The easier operation of staff can be incited somebody to action so that production efficiency is greatly improved by sealing rubber pad 15 and sealing nut 12 Separator 8 seals tighter with fixed plate 7.

In use, booster pump 2 and rotary electric machine 33 are electrically connected with external power supply, check valve 5 is first opened, so that mixing Liquid is passed through the inside of pressurizing tank 1 by inlet tube 4, when reaching a certain amount of, then again closes check valve 5, starting pressurization Pump 2, so that mixing liquid is passed through inside separator 8 through inlet opening 34, so that the particle polypeptide of small molecule is not needed with other Substance flowed in separating tube 11 through the filtering of polymer matrix cover 83, then the external control valve of separating tube 11 is closed again, Antibody diaphragm valve 13 is opened to flow to so that the higher antisolvent precipitation liquid of concentration comes out through 9 water conservancy diversion of antibody diversion pipe by flow guiding head 10 In collection device, when needing replacing polymer matrix cover 83, it is only necessary to first unscrew sealing nut 12, then partly by macromolecule Permeable membrane cover 83 is replaced.

It should be noted that, in this document, relational terms such as first and second and the like are used merely to a reality Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those Element, but also including other elements that are not explicitly listed, or further include for this process, method, article or equipment Intrinsic element.

While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art, It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.

Claims (6)

1. feline panleukopenia treatment single-chain antibody semifinished product precipitation separation device, including pressurizing tank (1), feature exists In: it is fixedly connected with booster pump (2) at the top of the pressurizing tank (1), and is communicated with inlet tube (4) on the right side of pressurizing tank (1), and It is fixedly connected on inlet tube (4) check valve (5), the bottom of pressurizing tank (1) inner cavity is fixedly connected with pressurization vortex device (3), the pressurization vortex device (3) includes vortex feed liquor block (31), and the side wall of vortex feed liquor block (31) offers feed liquor Hole (34), and be vortexed feed liquor block (31) at the top of be fixedly connected with motor casing (32), it is described vortex feed liquor block (31) top and It is fixedly connected with rotary electric machine (33) positioned at the inside of motor casing (32), the two sides of pressurizing tank (1) bottom are fixedly connected with Support fixed plate (6), and support fixed plate (6) bottom be fixedly connected with fixed plate (7), the bottom of the pressurizing tank (1) and Bottom positioned at pressurization vortex device (3) is communicated with separator (8), and the bottom of the separator (8) passes through sealing nut (12) it is connect with the screw top of fixed plate (7).

2. feline panleukopenia treatment single-chain antibody semifinished product precipitation separation device according to claim 1, Be characterized in that: the separator (8) includes pressurization cylinder (86), the top of the pressurization cylinder (86) and the bottom of pressurizing tank (1) It is connected, and the inner wall of pressurization cylinder (86) is fixedly connected with fixed saturating plate (82), passes through axis at the top of the saturating plate of fixation (82) It holds and is rotatably connected to rotation axis (84).

3. feline panleukopenia treatment single-chain antibody semifinished product precipitation separation device according to claim 2, Be characterized in that: the top of the rotation axis (84) is fixedly connected with one end of rotary electric machine (33) output shaft, the rotation axis (84) surface is fixedly connected with rotation pressurization spiral plate (85).

4. feline panleukopenia treatment single-chain antibody semifinished product precipitation separation device according to claim 1, Be characterized in that: the bottom of the fixed plate (7) and be located at pressurization cylinder (86) bottom be fixedly connected with fixed thread pipe (14), institute It states and is connected with sealing rubber pad (15) between the top of fixed thread pipe (14) and the bottom of pressurization cylinder (86).

5. feline panleukopenia treatment single-chain antibody semifinished product precipitation separation device according to claim 2, Be characterized in that: the inner wall of pressurization cylinder (86) bottom is fixedly connected with retainer ring (81), the inside and position of the pressurization cylinder (86) Polymer matrix cover (83) are connected in the basal sliding of the saturating plate of fixation (82).

6. feline panleukopenia treatment single-chain antibody semifinished product precipitation separation device according to claim 2, It is characterized in that: being communicated with antibody diversion pipe (9) between two pressurization cylinders (86), and antibody diversion pipe (9) is far from separation dress The one end of (8) is set through fixed plate (7) and extends to the bottom of fixed plate (7), is fixedly connected on the antibody diversion pipe (9) Antibody diaphragm valve (13), one end that the antibody diversion pipe (9) is located at fixed plate (7) bottom is communicated with flow guiding head (10), described The bottom of fixed plate (7) and be located at separator (8) immediately below be communicated with separating tube (11).