CN208307281U - Cell freezing storage device towards biological 3D printing - Google Patents
Cell freezing storage device towards biological 3D printing Download PDFInfo
- Publication number
- CN208307281U CN208307281U CN201820922427.0U CN201820922427U CN208307281U CN 208307281 U CN208307281 U CN 208307281U CN 201820922427 U CN201820922427 U CN 201820922427U CN 208307281 U CN208307281 U CN 208307281U
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- China
- Prior art keywords
- cabinet
- driving
- ratchet
- case lid
- mandril
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn - After Issue
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Abstract
The utility model discloses a kind of cell freezing storage devices towards biological 3D printing, including cabinet, the case lid connecting with cabinet and are located in the box body access device；The access device includes the big pipe of cell cryopreservation, storage turntable, ratchet, driving pawl, driving swing rod, driving push rod, detent, fixed link, support construction, connecting rod, mandril and torsionspring；Utility model device is small in size, light weight, modularization, portable 3D printer can be installed on, improve the heavy disadvantage of above-mentioned existing storage device, improve the safety and convenience of access link, the low temperature environment that can save cell the long period is created, the application places of motorization are adapted to.
Description
Technical field
The utility model belongs to mechanical engineering, biological 3D printing technique field, and in particular to one kind is towards biological 3D printing
Portable cell freezer storage device.
Background technique
Different therapeutic schemes is taken in treatment to human body damaged skin according to wound area.If the surface of a wound is smaller, clinically
It is general to use directly wrapping or autotransplantation；If the surface of a wound is very big, the method for generalling use heteroplastic transplantation,
Own health dermatoplasty will lead to the skin deficiencies of patient with severe symptoms, cause secondary damage；And skin donation meeting
Cause immunological rejection.Therefore using the patients own cells and biomaterial turned out, the skin of artificial skin is printed
Injury in treating mode is in widespread attention.
Cell storage existing scheme for biological 3D printing, which is generally, to be stored in large-scale liquid nitrogen container or refrigerator, is placed in
Low temperature environment can be frozen pole for a long time.Defrosting is pulled out when needing using cell, then by the cryopreservation tube equipped with cell.It is this
Although scheme is simple, have the following deficiencies:
Storage device is excessively heavy, is only applicable to the fixed environment such as laboratory, cannot be adapted to motor-driven, flexible use
It is required that.This defect has kept use of the portable 3D printer in field emergency in check.
Cell cryopreservation tube is manually pulled out or is immersed from liquid nitrogen by this scheme needs, if the misoperation in access procedure
It is easy to cause on the person and is stained with liquid nitrogen, in turn result in the harm such as frostbite.
Summary of the invention
The basic principle that the utility model is saved based on cell devises a kind of portable cell freezing towards 3D printing
Storage device.Utility model device is small in size, light weight, modularization, can be installed on portable 3D printer, improve
The heavy disadvantage for stating existing storage device, improves the safety and convenience of access link, and creating one can the long period
The low temperature environment for saving cell, adapts to the application places of motorization.
The technical solution of the utility model is specific as follows:
A kind of cell freezing storage device towards biological 3D printing, including cabinet, the case lid connecting with cabinet and is located at
The intracorporal access device of case；The access device includes the big pipe of cell cryopreservation, storage turntable, ratchet, driving pawl, driving pendulum
Bar, driving push rod, detent, fixed link, support construction, connecting rod, mandril and torsionspring；
Support construction bottom and cabinet are connected, and top is rotatably connected with ratchet center；Storage turntable is mounted on ratchet
And the two is concentric, storage turntable is equipped with rounded evenly arranged circular hole, and the big pipe of cell cryopreservation is placed in circular hole；Driving
Pawl and detent, which are equipped with torsionspring, is close to it with ratchet always；Wherein driving pawl and driving swing rod are hinged, only
Pawl is hinged with fixed link, drives swing rod one end and support construction top hinged, and driving push rod one end passes through support construction bottom
Portion and with connecting rod is hinged, connecting rod and mandril are hinged；
Mandril is located at the circular hole bottom of storage turntable, and each circular hole bottom is equipped with the aperture through ratchet, aperture for
Mandril passes through；When ratchet often turns over a ratchet angle, the storage turntable at the top of mandril is also just rotated into next circular hole；
Fixed link is fixedly connected with cabinet；The other end of swing rod, driving push rod is driven to be pierced by cabinet；
Cooling coil is equipped in cabinet, cabinet is equipped with ventilative screw, ventilative nozzle；Ventilative nozzle and cooling coil phase
Even, screw setting is breathed freely in ventilative nozzle.
Preferably, the cabinet is made of metal layer, heat insulation layer and movable interlayer；Metal layer is internally positioned, heat insulation layer
Arc-shaped cavity is equipped between outside, metal layer and heat insulation layer, movable interlayer is arc-shaped to be located in arc-shaped cavity, movable interlayer
It is connected with driving swing rod；The translot swung for driving swing rod is equipped on metal layer, heat insulation layer.Movable interlayer is located at box body wall
At translot, when driving swing rod to shake, movable interlayer follows driving swing rod mobile, always separates the environment inside and outside translot, subtracts
Few heat exchange through translot.Preferably, the movable interlayer is insulation material.
Preferably, the ventilative screw and ventilative nozzle are threadedly coupled, cooling coil and the welding of box body wall inner wall, thoroughly
Gas tube orifice passes through box body wall and cooling tube welds.
Further, the ventilative screw includes screw and cellular insulant；Screw center is through-hole, porous insulation
Material fills in through-holes, and the two is interference connection.It is had during liquid nitrogen endothermic temperature is raised and is partially converted into nitrogen, nitrogen
Device can be discharged by cellular insulant.
Preferably, the case lid including metal layer, heat insulation layer by forming；Metal layer is under, and heat insulation layer is in upper, the two use
Gluing jail, case lid are equipped with a case lid mouth；Case lid mouth is located at right above mandril, and case lid mouth diameter is greater than the big pipe of cell cryopreservation
Diameter；Case lid mouth is equipped with a bolt.
The utility model using it is close around cooling tube, pour into liquid nitrogen in pipe, the close contact area around cooling tube and air is big,
Heat absorption efficiency is high, to manufacture the environment of a low temperature in box house.This scheme greatly reduces the amount of required liquid nitrogen, from
And mitigating the weight of single unit system, the low temperature environment of creation is enough to make cell survival for a long time.In addition, the insulation of cabinet exterior
The heat exchange of layer reduction cabinet inside and outside, so that in guard box body the long period low temperature environment can be in.
The utility model designs access mechanism, has evaded access wind using the kinetic characteristic of the unidirectional stepping of ratchet mechanism
Heat exchange is reduced in danger, convenient and efficient.There are two mutually independent driving links for the access mechanism.Lower end is driving push rod, front and back
Promotion can drive mandril to move up and down, and the aperture that mandril passes through under storage turntable goes out the big tube top of cell cryopreservation, the hole on case lid
With a certain circular hole coaxial heart of storage turntable, the big pipe of cell cryopreservation is taken out from case cover hole after being ejected.Upper end is driving swing rod,
Shaking swing rod drives ratchet to make to store turntable rotation, is changed to next circular hole face case cover hole, can so take out next thin
Born of the same parents freeze big pipe.In addition, as soon as group eight cryopreservation tubes can be packed into the big pipe of cell cryopreservation, thus take can once obtain it is more thin
Born of the same parents.Note: case cover hole is tightened with bolt when not using device and is blocked, and heat is avoided to exchange through the hole.
Detailed description of the invention
Fig. 1 is (removing case lid) schematic diagram figure inside the device of the utility model；
Fig. 2 is the device appearance schematic diagram of the utility model.
Fig. 3 is the access mechanism schematic diagram of the utility model.
Fig. 4 is the ratchet, click-fit schematic diagram of the utility model.
Fig. 5 is the ventilative screw schematic diagram of the utility model.
Fig. 6 is the movable Mezzanine Map of the utility model.
Specific embodiment
The utility model is described further below with reference to embodiment and attached drawing.
As shown in Figs 1-4, a kind of cell freezing storage device towards biological 3D printing of the utility model, including cabinet
1, the case lid 12 and the access device in cabinet 1 being connect with cabinet 1；The access device include the big pipe 5 of cell cryopreservation,
Store turntable 6, ratchet 7, driving pawl 8, driving swing rod 9, driving push rod 10, detent 11, fixed link 13, support construction
14, connecting rod 15, mandril 16 and torsionspring 21；
14 bottom of support construction and cabinet 1 are connected, and top is rotatably connected with 7 center of ratchet；Storage turntable 6 is mounted on spine
On wheel 7 and the two is concentric, and storage turntable 6 is equipped with rounded evenly arranged circular hole, and the big pipe 5 of cell cryopreservation is placed in circular hole
It is interior；Driving pawl 8 and detent 11, which are equipped with torsionspring 21, is close to it with ratchet 7 always；Wherein driving pawl 8 and drive
Movable pendulum bar 9 is hinged, and detent 11 and fixed link 13 are hinged, drives 9 one end of swing rod and 14 top of support construction hinged, driving pushes away
10 one end of bar pass through 14 bottom of support construction and with connecting rod 15 is hinged, connecting rod 15 and mandril 16 are hinged；
Mandril 16 is located at the circular hole bottom of storage turntable 6, and each circular hole bottom is equipped with the aperture through ratchet 7, aperture
It is passed through for mandril 16；When ratchet often turns over a ratchet angle, the storage turntable 6 at 16 top of mandril is also just rotated into next
Circular hole；
Fixed link 13 is fixedly connected with cabinet 1；The other end of swing rod 9, driving push rod 10 is driven to be pierced by cabinet 1；
Cooling coil 4 is equipped in cabinet 1, cabinet 1 is equipped with ventilative screw 2, ventilative nozzle 3；Ventilative nozzle 3 and cooler pan
Pipe 4 is connected, and screw 2 of breathing freely is arranged in ventilative nozzle 3.
The course of work of the utility model is as follows: several cryopreservation tubes equipped with cell are packed into the big pipe of cell cryopreservation, it will be thin
Born of the same parents freeze big pipe and are put into the circular hole of storage turntable according to this；
Enough liquid nitrogen are perfused inwards by ventilative nozzle, screw nozzle with ventilative screw；
Case lid is covered, case lid mouth is screwed with bolt, carries out freezer storage；
When needing to take out cell, the bolt of case lid mouth is opened；Driving push rod is pushed, promotion is driven through connecting rod and drives top
Bar moves upwards, and the big tube top of cell cryopreservation is gone out case lid mouth by mandril, can take the big pipe of cell cryopreservation away；
Every primary driving swing rod of shake toward post-tensioning again toward be pushed forward be it is primary, storage turntable rotates a ratchet unit, under making
Circular hole on one storage turntable is directed at case lid mouth；In schematic diagram shown in Fig. 4, every shake is primary to drive swing rod, and ratchet is
A ratchet unit is counterclockwise selected, detent 11 prevents ratchet from returning when driving swing rod movement for blocking main ratchet
It moves back.Driving push rod is pushed, the big tube top of cell cryopreservation can be gone out into case lid mouth again, if cell is taken to finish, screw case lid with bolt
Mouthful.
As shown in fig. 6, the cabinet 1 is by metal layer 19, heat insulation layer in a specific embodiment of the utility model
18 and movable interlayer 20 constitute；Metal layer is internally positioned, and heat insulation layer is located at outside, and it is empty that arc is equipped between metal layer and heat insulation layer
Chamber, movable interlayer is arc-shaped to be located in arc-shaped cavity, and movable interlayer and driving swing rod 9 are connected；It is equipped on metal layer, heat insulation layer
The translot swung for driving swing rod 9.Movable interlayer is located at the translot of box body wall, when driving the shake of swing rod 9, movable interlayer with
It is mobile with driving swing rod, the environment inside and outside translot is separated always, reduces the heat exchange through translot.Preferably, described can
Dynamic interlayer is insulation material.
In a specific embodiment of the utility model, the ventilative screw and ventilative nozzle are threadedly coupled, cold
But coil pipe and the welding of box body wall inner wall, nozzle of breathing freely passes through box body wall and cooling tube welds.
As shown in figure 5, in a specific embodiment of the utility model, the ventilative screw includes screw and porous
Heat-insulating material 17；Screw center is through-hole, and cellular insulant fills in through-holes, and the two is interference connection.Liquid nitrogen endothermic temperature
It is had during raised and is partially converted into nitrogen, nitrogen can be discharged device by cellular insulant.
In a specific embodiment of the utility model, the case lid 12 including metal layer, heat insulation layer by forming；Gold
Belong to layer under, upper, the two is glued heat insulation layer, and case lid 12 is equipped with a case lid mouth；Case lid mouth is located at right above mandril 16,
And case lid mouth diameter is greater than the diameter of the big pipe 5 of cell cryopreservation；Case lid mouth is equipped with a bolt.
The utility model using it is close around cooling tube, pour into liquid nitrogen in pipe, the close contact area around cooling tube and air is big,
Heat absorption efficiency is high, to manufacture the environment of a low temperature in box house.This scheme greatly reduces the amount of required liquid nitrogen, from
And mitigating the weight of single unit system, the low temperature environment of creation is enough to make cell survival for a long time.In addition, the insulation of cabinet exterior
The heat exchange of layer reduction cabinet inside and outside, so that in guard box body the long period low temperature environment can be in.
The utility model designs access mechanism, has evaded access wind using the kinetic characteristic of the unidirectional stepping of ratchet mechanism
Heat exchange is reduced in danger, convenient and efficient.There are two mutually independent driving links for the access mechanism.Lower end is driving push rod, front and back
Promotion can drive mandril to move up and down, and the aperture that mandril passes through under storage turntable goes out the big tube top of cell cryopreservation, the hole on case lid
With a certain circular hole coaxial heart of storage turntable, the big pipe of cell cryopreservation is taken out from case cover hole after being ejected.Upper end is driving swing rod,
Shaking swing rod drives ratchet to make to store turntable rotation, is changed to next circular hole face case cover hole, can so take out next thin
Born of the same parents freeze big pipe.In addition, as soon as group eight cryopreservation tubes can be packed into the big pipe of cell cryopreservation, thus take can once obtain it is more thin
Born of the same parents.Note: case cover hole is tightened with bolt when not using device and is blocked, and heat is avoided to exchange through the hole.
Claims (5)
1. a kind of cell freezing storage device towards biological 3D printing, it is characterised in that even including cabinet (1), with cabinet (1)
The case lid (12) connect and the access device being located in cabinet (1)；The access device includes the big pipe of cell cryopreservation (5), storage
Turntable (6), ratchet (7), driving pawl (8), driving swing rod (9), driving push rod (10), detent (11), fixed link (13),
Support construction (14), connecting rod (15), mandril (16) and torsionspring (21)；
Support construction (14) bottom and cabinet (1) are connected, and top is rotatably connected with ratchet (7) center；Store turntable (6) installation
On ratchet (7) and the two is concentric, and storage turntable (6) is equipped with rounded evenly arranged circular hole, the big pipe of cell cryopreservation (5)
It is placed in circular hole；Driving pawl (8) and detent (11), which are equipped with torsionspring (21), keeps it tight with ratchet (7) always
Patch；Wherein hingedly, detent (11) and fixed link (13) hingedly, drive swing rod (9) for driving pawl (8) and driving swing rod (9)
One end and support construction (14) top are hinged, and driving push rod (10) one end passes through support construction (14) bottom and cuts with scissors with connecting rod (15)
Connect, connecting rod (15) and mandril (16) it is hinged；
Mandril (16) is located at the circular hole bottom of storage turntable (6), and each circular hole bottom is equipped with the aperture through ratchet (7), small
Hole passes through for mandril (16)；Storage turntable (6) also positive improvement when ratchet often turns over a ratchet angle, at the top of mandril (16)
Move next circular hole；
Fixed link (13) is fixedly connected with cabinet (1)；The other end of swing rod (9), driving push rod (10) is driven to be pierced by cabinet
(1)；
Cooling coil (4) are equipped in cabinet (1), cabinet (1) is equipped with ventilative screw (2), ventilative nozzle (3)；Ventilative nozzle (3)
It is connected with cooling coil (4), breathes freely screw (2) setting in ventilative nozzle (3)；
Case lid (12) is equipped with a case lid mouth；Case lid mouth is located at right above mandril (16), and case lid mouth diameter is greater than cell cryopreservation
The diameter of big pipe (5)；Case lid mouth is equipped with a bolt.
2. the cell freezing storage device according to claim 1 towards biological 3D printing, it is characterised in that the case
Body (1) is made of metal layer (19), heat insulation layer (18) and movable interlayer (20)；Metal layer is internally positioned, and heat insulation layer is located at outside,
Arc-shaped cavity is equipped between metal layer and heat insulation layer, movable interlayer is arc-shaped to be located in arc-shaped cavity, and movable interlayer and driving are put
Bar (9) is connected；The translot swung for driving swing rod (9) is equipped on metal layer, heat insulation layer.
3. the cell freezing storage device according to claim 1 towards biological 3D printing, it is characterised in that described is saturating
Gas screw and ventilative nozzle are threadedly coupled, and cooling coil and the welding of box body wall inner wall, nozzle of breathing freely pass through box body wall and cooling
Pipe welding.
4. the cell freezing storage device according to claim 1 towards biological 3D printing, it is characterised in that described is saturating
Gas screw includes screw and cellular insulant (17)；Screw center is through-hole, and cellular insulant fills in through-holes, and the two is
Interference connection.
5. the cell freezing storage device according to claim 1 towards biological 3D printing, it is characterised in that the case
Lid (12) including metal layer, heat insulation layer by forming；Metal layer is under, and upper, the two is glued heat insulation layer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820922427.0U CN208307281U (en) | 2018-06-14 | 2018-06-14 | Cell freezing storage device towards biological 3D printing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820922427.0U CN208307281U (en) | 2018-06-14 | 2018-06-14 | Cell freezing storage device towards biological 3D printing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208307281U true CN208307281U (en) | 2019-01-01 |
Family
ID=64707385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820922427.0U Withdrawn - After Issue CN208307281U (en) | 2018-06-14 | 2018-06-14 | Cell freezing storage device towards biological 3D printing |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208307281U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108639514A (en) * | 2018-06-14 | 2018-10-12 | 浙江大学 | A kind of cell freezing storage device and its method towards biological 3D printing |
| CN109941587A (en) * | 2019-03-19 | 2019-06-28 | 台州风达机器人科技有限公司 | A kind of diode storage device |
| CN111634558A (en) * | 2020-06-03 | 2020-09-08 | 杭州康馆科技有限公司 | Encrypted file extraction device for electronic commerce based on photoresistor |
| CN111685104A (en) * | 2020-07-08 | 2020-09-22 | 湖北明德健康科技有限公司 | Stem cell low-temperature storage device |
-
2018
- 2018-06-14 CN CN201820922427.0U patent/CN208307281U/en not_active Withdrawn - After Issue
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108639514A (en) * | 2018-06-14 | 2018-10-12 | 浙江大学 | A kind of cell freezing storage device and its method towards biological 3D printing |
| CN108639514B (en) * | 2018-06-14 | 2023-05-16 | 浙江大学 | Cell freezing storage device and method for biological 3D printing |
| CN109941587A (en) * | 2019-03-19 | 2019-06-28 | 台州风达机器人科技有限公司 | A kind of diode storage device |
| CN111634558A (en) * | 2020-06-03 | 2020-09-08 | 杭州康馆科技有限公司 | Encrypted file extraction device for electronic commerce based on photoresistor |
| CN111634558B (en) * | 2020-06-03 | 2021-11-30 | 聊城八月瓜大数据服务有限公司 | Encrypted file extraction device for electronic commerce based on photoresistor |
| CN111685104A (en) * | 2020-07-08 | 2020-09-22 | 湖北明德健康科技有限公司 | Stem cell low-temperature storage device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned | ||
| AV01 | Patent right actively abandoned | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20190101 Effective date of abandoning: 20230516 |
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| AV01 | Patent right actively abandoned |
Granted publication date: 20190101 Effective date of abandoning: 20230516 |