CN208297326U - Self-alignment Dim light measurement device - Google Patents
Self-alignment Dim light measurement device Download PDFInfo
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- CN208297326U CN208297326U CN201820863054.4U CN201820863054U CN208297326U CN 208297326 U CN208297326 U CN 208297326U CN 201820863054 U CN201820863054 U CN 201820863054U CN 208297326 U CN208297326 U CN 208297326U
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Abstract
The utility model relates to a kind of self-alignment Dim light measurement devices, comprising: cabinet, cabinet include prechamber, sensing chamber and reference chamber；Signal optical system, signal optical system include signal light collector and photon counting module, and signal light collector is set to prechamber, and photon counting module is set to sensing chamber；And reference optical system, reference optical system is used for the calibration of signal optical system, reference optical system includes diffuse-reflective cavity, the reference light source in diffuse-reflective cavity and photodetector, is electrically connected reference light source with the photoelectric control making sheet of photodetector and is connected to the diaphragm of photon counting module and diffuse-reflective cavity, and photoelectric control making sheet is electrically connected photon counting module；Diffuse-reflective cavity, reference light source, photodetector and photoelectric control making sheet are installed on reference chamber, diaphragm communication with detection room and reference chamber.It has and can improve the stability of calibration very well, and structure is simple, ensure that the characteristics of having saved cost on the basis of stability and its performance.
Description
Technical field
The utility model relates to chemiluminescence immunoassay detection device technical fields, more particularly to self-alignment Dim light measurement
Device.
Background technique
Chemiluminescence immunoassay detection belongs to Dim light measurement scope, and the temperature change of environment often produces Dim light measurement device
The problems such as raw temperature drift, cause Dim light measurement device to the non_uniform response of same standard signal light.Further, since device is old
The response that the factors such as change also result in Dim light measurement device changes.Traditional Dim light measurement device is in order to solve temperature drift and old
The problems such as change, mostly uses greatly complicated calibration light path system, such as various reflecting mirrors, spectroscope, optical filter, some calibration optics
System uses multi-disc plane mirror, and the angle change of reflected light is 2 times of mirror angle variation, and faint light detection is filled
It sets, small variation will have greatly changed to number of photons, this will directly affect the accuracy of calibration, moreover, this kind of dress
Set that structure is complicated, at high cost, assembly and commissioning requirements are high, batch production low efficiency, and to increase its unstable for complicated structure
The risk factor of property.
Utility model content
Based on this, it is necessary to which, in view of the above-mentioned problems, providing a kind of self-alignment Dim light measurement device, have to mention very well
The stability of height calibration, and structure is simple, ensure that the characteristics of having saved cost on the basis of stability and its performance.
A kind of self-alignment Dim light measurement device, comprising:
Cabinet, cabinet include reference chamber, prechamber and the sensing chamber for being connected to prechamber；
Signal optical system, signal optical system include signal light collector and photon counting module, signal light collector
The direction of the launch with photon counting module along signal light is set gradually, and signal light collector is set to prechamber, photon counting module
Set on sensing chamber；And
Reference optical system, reference optical system are used for the calibration of signal optical system, and reference optical system includes unrestrained anti-
Penetrate chamber, the reference light source in diffuse-reflective cavity with photodetector, be electrically connected the photoelectric control of reference light source and photodetector
Making sheet and the diaphragm for being connected to photon counting module and diffuse-reflective cavity, photoelectric control making sheet are electrically connected photon counting module；Diffuse-reflective cavity,
Reference light source, photodetector and photoelectric control making sheet are installed on reference chamber, diaphragm communication with detection room and reference chamber, reference light source
Light passes through diaphragm entering signal optical system in diffuse-reflective cavity body after diffusing reflection, and is projected to photon counting module.
Above-mentioned self-alignment Dim light measurement device, when detection, cabinet is connected to reader chamber to be realized closed, and extraneous light can not
It penetrates in cabinet, avoids the interference of ambient；It can control the output intensity of reference light source, reference light source by photoelectric control making sheet
The light of sending is detected that the light of fraction is logical by the diffusing reflection in diffuse-reflective cavity, some light by photodetector
It crosses diaphragm and is projected to photon counting module, optical signals are detected by photon counting module；The light of the reference light source of certain light intensity
It can not interfered by extraneous factor by the optical signal of diaphragm, photodetector connects quantitatively by the optical signal of diaphragm
The optical signal of receipts is to through the directly proportional by the received optical signal of photon counting module of diaphragm, and such reference light source is by photon counting
The received optical signal of module can accurately be measured indirectly by photodetector；If before not drifting about, the photoelectricity of the strong reference light source of X-ray
The received optical signal of detector and the ratio by the received optical signal of photon counting module for penetrating diaphragm are S0, work as photon counting
After temperature drift occurs for module, it is that X-ray is strong by the output intensity that photoelectric control making sheet controls reference light source, measures photodetector
Received optical signal and the ratio by the received optical signal of photon counting module for penetrating diaphragm are S1, are made with the S0 before not drifting about
Compare, obtain calibration factor F, when surveying reactant, photon counting module is compensated according to calibration factor F, i.e., to reality
Light signal carries out calibration calculating, obtains the reactant optical signal in accurate reaction vessel, reaches self-alignment effect；Self-correcting
Quasi- output light is that one kind diffuses, rather than direct light, can improve the stability of regulation light source, and structure letter very well
It is single, it ensure that the cost that device is greatly saved on the basis of stability and its performance.
Light-baffling device and light passing channel are equipped in diffuse-reflective cavity in one of the embodiments, the light of reference light source is saturating
It crosses light passing channel and enters diaphragm.
The diameter of diaphragm is 1~10mm in one of the embodiments,.
Diffuse-reflective cavity is square cavity in one of the embodiments,.
Reference light source and photodetector are installed on the same side in diffuse-reflective cavity, diaphragm in one of the embodiments,
Positioned at the side opposite with reference light source.
Reference light source uses LED light or OLED lamp in one of the embodiments,.
Photodetector is photodiode or avalanche photodide in one of the embodiments,.
Signal light collector is single convex lens in one of the embodiments,.
Photon counting module includes photon counting plate and the detection for being installed on photon counting plate in one of the embodiments,
Device.
Detector is photomultiplier tube in one of the embodiments,.
Detailed description of the invention
Fig. 1 is the schematic diagram of a preferred embodiment of the self-alignment Dim light measurement device of the utility model；
Fig. 2 is cross-sectional view of the self-alignment Dim light measurement device of Fig. 1 along the direction A-A；
Fig. 3 is the partial schematic diagram containing reference optical system in the self-alignment Dim light measurement device of Fig. 2；
Fig. 4 is the enlarged diagram of the part B of the self-alignment Dim light measurement device of Fig. 2.
Specific embodiment
The utility model will be described more fully below for the ease of understanding the utility model,.But this is practical
It is novel to realize in many different forms, however it is not limited to embodiment described herein.On the contrary, providing these implementations
The purpose of example is to make the understanding of the disclosure of the utility model more thorough and comprehensive.
Unless otherwise defined, all technical and scientific terms used herein are led with the technology for belonging to the utility model
The normally understood meaning of the technical staff in domain is identical.Terminology used in the description of the utility model herein only be
The purpose of description specific embodiment, it is not intended that in limitation the utility model.
It is referring to FIG. 1 to FIG. 4, the self-alignment Dim light measurement device 100 of one preferred embodiment of the utility model, application
It is detected in chemiluminescence immunoassay, when application, self-alignment 100 optical communication of Dim light measurement device indoor can produce light in reading
Learn the reaction vessel of signal.In one embodiment, once reaction vessel enters reader chamber, it is arranged in fast near reaction vessel
Door is closed, and the environment light around reaction vessel is covered.In one embodiment, reaction vessel is set in the hole location of disk body, can
It is rotated with disk body, disk body is located in an accommodating body, and disk body and accommodating body constitute reader chamber together.When reading, reaction vessel is with disk
Body turns to reading station.It will be understood by those skilled in the art that the optical signalling in reaction vessel is by anti-in reaction vessel
Answering object that chemiluminescence hair occurs should generate, for example directly shine class compounds acridine ester in corresponding preexciting liquid and exciting liquid
The chemistry hair of the chemiluminescence reaction of generation, chemiluminescent substrate spiral adamantane and its derivative under alkaline phosphatase enzymatic
Light reaction etc..
The self-alignment Dim light measurement device 100 includes cabinet 10, the signal optical system 20 being installed in cabinet 10
With reference optical system 30, cabinet 10 is mainly used for blocking extraneous environment light, and signal optical system 20 is used for collecting signal light
And it is converted to electric signal, reference optical system 30 provides the standard sources of calibration, the drift school for signal optical system 20
Standard, to adjust testing result, to keep testing result more acurrate.
As shown in Fig. 2, cabinet 10 includes prechamber 11, the sensing chamber 12 for being connected to prechamber 11 and communications signals optical system
20 reference chamber 13, prechamber 11 is neighbouring and is connected to reader chamber (not shown).
As shown in Fig. 2, signal optical system 20 includes signal light collector 21 and photon counting module 22, signal light is collected
Device 21 and photon counting module 22 are set gradually along the direction of the launch of signal light, and signal light collector 21 is set to prechamber 11, light
Sub-count module 22 is set to sensing chamber 12.When optical signal in test reaction container, reaction vessel is placed in reader chamber, and reaction is held
Reactant in device occurs chemical reaction and issues optical signal to surrounding, wherein the one side close to signal light collector 21 forms hair
Smooth surface, light-emitting surface are imaged on the photosurface of photon counting module 22 by signal light collector 21, and imaging surface size is just covered
Lid photosurface allows the stray light other than non-luminescent face to cannot be introduced into photon counting module alternatively, imaging surface is slightly less than photosurface
22, to reduce interference light or bias light interference.It is appreciated that signal light collector 21 is in the movable tune in the position of prechamber 11
Section, can distance of the adjustment signal light collector 21 relative to photon counting module 22, so that imaging surface is better covered photosurface,
Noise jamming is preferably minimized.
In one embodiment, signal light collector 21 is single convex lens, and convex lens plays the role of assembling light, Ke Yishou
The image formation by rays of collection light-emitting surface is incident upon on the photosurface of photon counting module 22, and the focal length of convex lens is fixed, and can easily be accommodated
Imaging.In addition, single convex lens can also further compact device structure and save the cost.In some embodiments, signal light is received
Storage 21 can also be the lens group that the lens group being made of multiple convex lens, convex lens and concavees lens form or optical fiber etc.,
Also the effect of the preferable photosurface collected light and image in photon counting module 22 can be obtained.
In one embodiment, photon counting module 22 includes detector 23, and detector 23 can be work in count mode
Under end window type photomultiplier tube (Photomultiplier tube, abridge PMT) or similar faint optical signal can be converted
At the device of electric signal, photomultiplier tube has high sensitivity, and fast response time, can rapidly obtain measurement result.Into one
Step ground, photon counting module 22 may also include photon counting plate 24.Detector 23 is mounted on photon counting plate 24 by mounting base
On, bleeder circuit, high-pressure modular, high gain signal amplifier, discriminator, pre-divider, number are additionally provided on photon counting plate 24
According to processor etc..It will be understood by those skilled in the art that in other embodiments, according to the function division of circuit board, photon meter
Number plate 24 may be one piece more than, such as can be two pieces or more, and muti-piece is directly connected to by electric wire.Connect from the output of pre-divider
It is connected to the data processor counted for photon pulse, in some embodiments, pre-divider also has the function of shaping pulse, makes
Pulse signal is more preferable.Optical signal, for example the transmitting optical signal that reaction solution generates out of reference optical system 30, reaction vessel can
To be irradiated on detector 23.
As shown in Fig. 2, reference optical system 30 include diffuse-reflective cavity 31, the reference light source 32 in diffuse-reflective cavity 31 with
Photodetector 33, the photoelectric control making sheet 34 and communications signals optical system 20 for being electrically connected reference light source 32 and photodetector 33
With the diaphragm 35 of diffuse-reflective cavity 31, photoelectric control making sheet 34 is electrically connected photon counting module 22, is mainly used for controlling and monitoring reference
The luminous intensity of light source 32.Diffuse-reflective cavity 31, reference light source 32, photodetector 33 and photoelectric control making sheet 34 are mounted on reference
Room 13, by 35 communications signals optical system 20 of diaphragm, the light of reference light source 32 is overflow reference chamber 13 in diffusing reflection cavity 31
It by 35 entering signal optical system 20 of diaphragm after reflection, and is projected on the photosurface of photon counting module 22, by photon meter
Digital-to-analogue block 22 detects.
In one embodiment, diffuse-reflective cavity 31 is cylindrical chamber, and the adjacent inner sidewall in cylindrical chamber is mutually perpendicular to, makes
Irreflexive light obtains repeatedly refraction and reflection, increases light path, obtains the diffusing reflection light of a variety of different light paths, in this way can be with
Make from the emergent light of diffuse-reflective cavity 31 more evenly and at random, to improve optical system to the tolerance of manufacture variation.
In one embodiment, reference light source 32 and photodetector 33 are installed on the same side in diffuse-reflective cavity 31, photoelectricity
Mounting height of the detector 33 in photoelectric control making sheet 34 is lower than reference light source 32, can reduce reference light source to greatest extent in this way
32 direct light projects on photodetector 33, effectively improves photodetector 33 and installs position disparity to reference light source 32
Tolerance.
In one embodiment, diaphragm 35 is located at the side opposite with reference light source 32, can get longer light path, further
Weaken the light intensity for being projected to the light of diaphragm 35.
In one embodiment, in order to further weaken the reference light into diaphragm 35, light-blocking dress is equipped in diffuse-reflective cavity 31
Set 36.For example the side of the close diaphragm 35 in diffuse-reflective cavity 31 is equipped with light-baffling device 36, the top of light-baffling device 36 is equipped with logical
Optical channel 37, some light of reference light source 32 enter diaphragm 35 through light passing channel 37 after diffusing reflection, are then projected to
Photon counting module 22.In one embodiment, light-baffling device 36 is a riser, for block the direct line of reference light source 32 into
Enter diaphragm 35, it is ensured that all diffuse by the light of diaphragm 35, avoid being projected to photon counting module 22 through diaphragm 35
Optical signal is excessive and damages photon counting module 22.It will be understood by those skilled in the art that light-baffling device 36 can also be other
Structure, as long as the direct line that can block reference light source 32 enters diaphragm 36.It light passing channel 37 can be by light-baffling device 36
It is formed between diffuse-reflective cavity 31, for example forms light passing channel 37 between 36 side of light-baffling device and the cavity wall of diffuse-reflective cavity 31；
Also it can be set on light-baffling device 36, for example open up light passing channel 37 on light-baffling device 36, light passing channel 37 can be logical
Light slit gap or hole.
In one embodiment, the inner wall of diffuse-reflective cavity 31 is coated with diffusing reflection coating, or is equipped with cloudy surface glass, to obtain
Preferable diffusing reflection effect.
The spectrum for the reference light that reference light source 32 emits matches the spectrum of the signal light of the detection of photon counting module 22 substantially
Characteristic, can reduce to the maximum extent in this way due to various PMT change spectral response caused by detect difference a possibility that.
In one embodiment, reference light source 32 be green light, such as when signal light be reaction vessel inside spin adamantane and
The luminous signal that chemical reaction generates occurs for its derivative.Reference light source 32 can also be blue light, such as when signal light is anti-
Answer acridinium ester in container that the luminous signal that chemical reaction generates occurs.More preferably, reference light source 32 uses LED light or OLED lamp,
LED light and OLED lamp are easily controllable, stable luminescence, can be used as standard sources use, and are that face shines, and light is relatively uniform,
Diffusing reflection effect is preferable, avoids light from excessively concentrating and most of light is reflected toward same direction, has violated irreflexive original intention.
In one embodiment, in order to keep structure more simple and compact, diaphragm 35 is the circle on the side wall of sensing chamber 12
Aperture, 35 communication with detection room 12 of diaphragm and reference chamber 13, the light of reference light source 32 pass through after diffusing reflection in diffuse-reflective cavity 31
35 entering signal optical system 20 of diaphragm, and it is projected to photon counting module 22.
In one embodiment, reference light may also pass through signal light collector 21, then be projected on detector 23, this
When, diaphragm 35 can be the circular opening on the side wall of prechamber 11, may also correct for signal light collector 21 to signal gloss
The influence of collection, diaphragm 35 is connected to prechamber and reference chamber, the light of reference light source 32 pass through after diffusing reflection in diffuse-reflective cavity 31
35 entering signal optical system 20 of diaphragm, and it is projected to photon counting module 22.
In one embodiment, diaphragm 35 is circular aperture, and the diameter of circular hole is 1~10mm, such as can be, but be not limited to
1mm, 2mm, 3.5mm, 4mm, 6mm, 6.5mm, 7mm, 7.5mm, 8mm, 8.5mm, 9mm, 9.5mm or 10mm etc. can be accurately controlled
Reference light source 32 penetrates the optical signal of diaphragm 35, while the reference light obtained after preferable weaken is projected to photon counting module
22.In other embodiments, diaphragm 35 can also be any entity for playing restriction effect to light beam in optical system, such as set
There is the hard light-proof material etc. of loophole.The setting of diaphragm 35 can guarantee the reference light source 32 for finally there was only very little part
Emit light projection to photon counting module 22, avoids exceeding the measurement range of photon counting module 22, even result in device failure.
In addition, disengaging diaphragm 35 reference light be all it is random diffuse, the transmitting light for avoiding reference light source 32 is directly incident on
On the detector of photon counting module 22, the installation site that can effectively reduce reference light source 32 changes caused by calibration result
Inaccuracy.
The change and decaying for emitting reference light source 32 light by diffuse-reflective cavity 31 and diaphragm 35, not only avoid existing skill
The use of the various optical devices such as diffuser plate, attenuator, reflecting mirror, has simplified structure, has saved cost in art, can also improve
The tolerance of variation during 100 pairs of the self-alignment Dim light measurement device manufacturings, i.e. the utility model Dim light measurement fill
The assembly precision for setting 100 pairs of reference light sources 32 is of less demanding.
In one embodiment, photodetector 33 is photodiode (PD, Photodiode) or avalanche photodide
(APD, Avalanche photodiode) or other similar devices that optical signal can be converted to electric signal.Photoelectricity is visited
Device 33 is surveyed for monitoring and the luminous intensity variations of feedback regulation reference light source 32.
Reference optical system 30, which feeds back and controls for the calibration to signal optical system 20, by photoelectric control making sheet 34, to be adjusted
The output intensity of reference light source 32 is saved, the light that reference light source 32 issues is by after the diffusing reflection in diffuse-reflective cavity 31, part
Light is detected that the light of fraction is projected to photon counting module 22 by diaphragm 35 by photodetector 33.According to diaphragm
35 and diffuse-reflective cavity 31 architectural characteristic, the light of the reference light source 32 of certain light intensity is that can determine by the optical signal of diaphragm 35
Amount, do not interfered by extraneous factor by the optical signal of diaphragm 35, the received optical signal of photodetector 33 with through diaphragm
35 it is directly proportional by the received optical signal of photon counting module 22, in this way, reference light source 32 is received by photon counting module 22
Optical signal can pass through the accurate measurement indirectly of photodetector 33 simultaneously.
Such as: it sets before not drifting about, the strong reference light source of X-ray, the received optical signal of photodetector 33 and transmission diaphragm 35
The ratio by the received optical signal of photon counting module 22 be S0.After photon counting module 22 drifts about, pass through photoelectricity
The output intensity that control panel 34 controls reference light source 32 is that X-ray is strong, measures the received optical signal of photodetector 33 and penetrates light
Door screen 35 the ratio by the received optical signal of photon counting module 22 be S1, make comparisons with the S0 before not drifting about, obtain calibration because
Sub- F.
After obtaining calibration factor F, then the reactant in actual measurement reaction vessel is carried out, the reaction vessel equipped with reactant is set
In reader chamber, the optical signal Z of reactant is measured, photon counting module 22 is compensated according to calibration factor F, i.e., to optical signal
Z carries out calibration calculating, obtains the reactant optical signal in accurate reaction vessel, reaches self-alignment effect.
It should be noted that calibration and detection when, cabinet 10 be connected to reader chamber realization it is closed, extraneous light can not penetrate
In cabinet 10, the interference of ambient is avoided.
The self-alignment Dim light measurement device 100 of the utility model, signal optical system 20 are combined with reference optical system 30,
Reduce the probability that is affected by various factors and leading to measurement data inaccuracy of photon counting module 22.Reference optical system 30 is adopted
Spherical structure is integrated with class, output light is that one kind diffuses, rather than direct light, the stability of reference light source can be improved very well,
Complicated optical device is not needed, complicated structure is reduced while improving calibration accuracy, improves its stability, and structure
Simply, weight is small, and the manufacturing requires low, ensure that the cost that device is greatly saved on the basis of stability and its performance.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
A kind of embodiment of the utility model above described embodiment only expresses, the description thereof is more specific and detailed,
But it cannot be understood as the limitations to utility model patent range.It should be pointed out that for the common skill of this field
For art personnel, without departing from the concept of the premise utility, various modifications and improvements can be made, these are belonged to
The protection scope of the utility model.Therefore, the scope of protection shall be subject to the appended claims for the utility model patent.
Claims (10)
1. a kind of self-alignment Dim light measurement device characterized by comprising
Cabinet, the cabinet include the sensing chamber of reference chamber, prechamber and the connection prechamber；
Signal optical system, the signal optical system include signal light collector and photon counting module, and the signal light is received
Storage and photon counting module are set gradually along the direction of the launch of signal light, and the signal light collector is set to the prechamber,
The photon counting module is set to the sensing chamber；And
Reference optical system, the reference optical system are used for the calibration of the signal optical system, the reference optical system
Including diffuse-reflective cavity, the reference light source in the diffuse-reflective cavity and photodetector, it is electrically connected the reference light source and light
The photoelectric control making sheet of electric explorer and the diaphragm of connection the signal optical system and diffuse-reflective cavity, the photoelectric control making sheet are electrically connected
Connect the photon counting module；The diffuse-reflective cavity, reference light source, photodetector and photoelectric control making sheet are installed on the reference
Room, the diaphragm are connected to the signal optical system and the reference chamber, and the light of the reference light source is in the diffuse-reflective cavity
The signal optical system is entered by the diaphragm after internal diffusing reflection, and is projected to the photon counting module.
2. self-alignment Dim light measurement device according to claim 1, which is characterized in that be equipped with gear in the diffuse-reflective cavity
The light in electro-optical device and light passing channel, the reference light source enters the diaphragm through the light passing channel.
3. self-alignment Dim light measurement device according to claim 1, which is characterized in that the diameter of the diaphragm be 1~
10mm。
4. self-alignment Dim light measurement device according to any one of claims 1 to 3, which is characterized in that the diffusing reflection
Chamber is cylindrical chamber.
5. self-alignment Dim light measurement device according to claim 4, which is characterized in that the reference light source and photoelectricity are visited
It surveys device and is installed on the same side in the diffuse-reflective cavity, the diaphragm is located at the side opposite with the reference light source.
6. self-alignment Dim light measurement device according to claim 1, which is characterized in that the reference light source uses LED
Lamp or OLED lamp.
7. self-alignment Dim light measurement device according to claim 1, which is characterized in that the photodetector is photoelectricity
Diode or avalanche photodide.
8. self-alignment Dim light measurement device according to claim 1, which is characterized in that the signal light collector is single
A convex lens.
9. self-alignment Dim light measurement device according to claim 1, which is characterized in that the photon counting module includes
Photon counting plate and the detector for being installed on the photon counting plate.
10. self-alignment Dim light measurement device according to claim 9, which is characterized in that the detector is photoelectricity times
Increase pipe.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108444917A (en) * | 2018-06-05 | 2018-08-24 | 深圳迎凯生物科技有限公司 | Self-alignment Dim light measurement device |
| CN111060199A (en) * | 2019-12-26 | 2020-04-24 | 迪瑞医疗科技股份有限公司 | Optical detection system with self-checking device and self-checking method |
-
2018
- 2018-06-05 CN CN201820863054.4U patent/CN208297326U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108444917A (en) * | 2018-06-05 | 2018-08-24 | 深圳迎凯生物科技有限公司 | Self-alignment Dim light measurement device |
| CN108444917B (en) * | 2018-06-05 | 2024-07-26 | 深圳迎凯生物科技有限公司 | Self-calibrating dim light detection device |
| CN111060199A (en) * | 2019-12-26 | 2020-04-24 | 迪瑞医疗科技股份有限公司 | Optical detection system with self-checking device and self-checking method |
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