CN208206707U - A kind of living cells hardness measuring device - Google Patents
A kind of living cells hardness measuring device Download PDFInfo
- Publication number
- CN208206707U CN208206707U CN201820659811.6U CN201820659811U CN208206707U CN 208206707 U CN208206707 U CN 208206707U CN 201820659811 U CN201820659811 U CN 201820659811U CN 208206707 U CN208206707 U CN 208206707U
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- China
- Prior art keywords
- living cells
- gear
- slide
- bracket
- measuring device
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Abstract
The utility model discloses a kind of living cells hardness measuring devices, including pedestal, the top of the pedestal is fixedly connected with column, the upper end of the column is fixedly installed with microscope ontology, the side of the second gear is fixedly connected with objective table, micro slide is provided on the objective table, electric heating wire is embedded in the micro slide, bracket is fixedly connected on the pedestal, the top of the bracket is slidably fitted with slide bar, the lower end of the slide bar is equipped with hardometer, the scleroscopic lower end is equipped with test probe, the side of the slide bar is fixedly connected with rack gear, the top of the bracket is equipped with the second adjusting knob connecting with rack-driving.It can quickly adjust and realize and the hardness of living cells is measured；By the design of micro slide and heating wire, micro slide can be made to keep certain cells survival temperature, and can measure at a temperature of different productions in measurement process, the hardness of living cells, measurement data is more acurrate.
Description
Technical field
The utility model relates to biological cell technical field, specially a kind of living cells hardness measuring device.
Background technique
Cyto-mechanics is a Disciplinary Frontiers of biomethanics and an important component of organizational engineering.It
It is related to cell mechanical property such as cell membrane, the deformation of cytoskeleton, elastic constant, viscoplasticity, adhesion strength under mechanical loading effect
Influence and its mechanism of the research and mechanics factor of energy to cell growth, development, mature, proliferation, aging and death etc. are ground
Study carefully.For cyto-mechanics, the key of research is the Mechanical loading mode of cell；So finding suitable cell load side
Method and cytomorphosis and relevant Biological measurement means are the matters of utmost importance of cyto-mechanics research.
When the hardness to cell is tested, generally it is difficult to test the hardness of living cells, many living cells pair
There is certain requirement in the temperature of existence, and the activity of cell at different temperatures is different, it is poor that the hardness on surface has generation
It is different.It would therefore be desirable to propose a kind of living cells convenient for measurement living cells hardness and living cells hardness at different temperatures
Hardness measuring device.
Utility model content
The purpose of this utility model is to provide a kind of living cells hardness measuring devices, it can be ensured that the existence temperature of living cells
Degree, and can be under single sampling, the hardness of measurement living cells at different temperatures is very convenient；To solve above-mentioned background skill
The problem of being proposed in art.
To achieve the above object, the utility model provides the following technical solutions: a kind of living cells hardness measuring device, including
Pedestal, the top of the pedestal are fixedly connected with column, and the upper end of the column is fixedly installed with microscope ontology, the column
Upper fixing sleeve is connected to bearing, and fixing sleeve is connected to second gear on the bearing, and screw thread is equipped with screw rod, the spiral shell on the pedestal
Fixing sleeve is connected to the first gear that connection is engaged with second gear on bar, and the side of the second gear is fixedly connected with loading
Platform is provided with micro slide on the objective table, electric heating wire is embedded in the micro slide, is fixedly connected with branch on the pedestal
Frame, the top of the bracket are slidably fitted with slide bar, and the lower end of the slide bar is equipped with hardometer, the scleroscopic lower end peace
Equipped with test probe, the side of the slide bar is fixedly connected with rack gear, and the top of the bracket is equipped with to be connect with rack-driving
The second adjusting knob.
Preferably, the top of the micro slide opens up fluted, is equipped with temperature sensor on the micro slide.
Preferably, slide opening is offered on the bracket, the sliding bar is plugged in slide opening, second adjusting knob
Side be fixedly connected with the shaft through bracket, the third gear that connection is engaged with rack is fixedly installed in the shaft.
Preferably, the lower end diameter of the test probe is 10-20 microns.
Preferably, the upper end of the screw rod is fixedly installed with the first adjusting knob, and the width of the first gear is greater than the
2-3 times of the width of two gears.
Preferably, the side of the column is equipped with the reflective mirror that cooperation microscope ontology uses.
Compared with prior art, the utility model has the beneficial effects that
1, by microscope ontology, hardometer and the design for testing probe, it can quickly adjust and realize to living cells
Hardness measure；
2, by the design of micro slide and heating wire, micro slide can be made to keep certain cell in measurement process
Survival temperature, and can measure at a temperature of different productions, the hardness of living cells, measurement data is more acurrate.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model；
Fig. 2 is the overlooking structure diagram of the utility model bracket；
Fig. 3 is the structural schematic diagram of the utility model micro slide.
In figure: 1 pedestal, 2 screw rods, 3 first gears, 4 first adjusting knobs, 5 second gears, 6 microscope ontologies, 7 columns,
8 bearings, 9 reflective mirrors, 10 objective tables, 11 micro slides, 12 brackets, 13 test probes, 14 hardometers, 15 second adjusting knobs, 16
Rack gear, 17 slide bars, 18 slide openings, 19 shafts, 20 third gears, 21 heating wire, 22 temperature sensors, 23 grooves.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
Fig. 1-3 is please referred to, the utility model provides a kind of technical solution: the living cells hardness measuring device, including pedestal
1, the top of the pedestal 1 is fixedly connected with column 7, and the upper end of the column 7 is fixedly installed with microscope ontology 6, described vertical
Fixing sleeve is connected to bearing 8 on column 7, and fixing sleeve is connected to second gear 5 on the bearing 8, and screw thread is equipped with screw rod on the pedestal 1
2, fixing sleeve is connected to the first gear 3 that connection is engaged with second gear 5 on the screw rod 2, and the side of the second gear 5 is fixed
It is connected with objective table 10, micro slide 11 is provided on the objective table 10, is embedded with electric heating wire 21, institute in the micro slide 11
It states and is fixedly connected with bracket 12 on pedestal 1, the top of the bracket 12 is slidably fitted with slide bar 17, the lower end peace of the slide bar 17
Equipped with hardometer 14, the lower end of the hardometer 14 is equipped with test probe 13, and the side of the slide bar 17 is fixedly connected with teeth
Item 16, the top of the bracket 12 are equipped with the second adjusting knob 15 being sequentially connected with rack gear 16.
Specifically, the top of the micro slide 11 opens up fluted 23, temperature sensor is installed on the micro slide 11
22.The design of groove 23 takes like cell convenient for drop.
Specifically, offer slide opening 18 on the bracket 12,17 sliding plug of slide bar is in slide opening 18, described second
The side of adjusting knob 15 is fixedly connected with the shaft 19 through bracket 12, is fixedly installed in the shaft 19 and nibbles with rack gear 16
Close the third gear 20 of connection.It can move up and down test probe 13 by the second adjusting knob 15, convenient for measurement.
Specifically, the lower end diameter of the test probe 13 is 10-20 microns.Test probe 13 chooses suitable diameter,
Convenient for measuring different size of cell hardness.
Specifically, the upper end of the screw rod 2 is fixedly installed with the first adjusting knob 4, the width of the first gear 3 is greater than
2-3 times of the width of second gear 5.When screw rod 2 is rotated up and down, first gear 3 is engaged with second gear 5 first gear 3 always
Connection.
Specifically, the side of the column 7 is equipped with the reflective mirror 9 that cooperation microscope ontology 6 uses.
Working principle: when in use, can be fast by microscope ontology 6, hardometer 14 and the design for testing probe 13
Velocity modulation section and realize the hardness of living cells is measured；By the design of micro slide 11 and heating wire 21, can measure
In the process, so that micro slide 11 is kept certain cells survival temperature, and can measure at a temperature of different productions, living cells it is hard
Degree, measurement data are more acurrate.
While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art,
It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired
Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.
Claims (6)
1. a kind of living cells hardness measuring device, including pedestal (1), it is characterised in that: the top of the pedestal (1) is fixedly connected
Have column (7), the upper end of the column (7) is fixedly installed with microscope ontology (6), and fixing sleeve is connected to axis on the column (7)
It holds (8), fixing sleeve is connected to second gear (5) on the bearing (8), and screw thread is equipped with screw rod (2) on the pedestal (1), described
Fixing sleeve is connected to the first gear (3) that connection is engaged with second gear (5) on screw rod (2), and the side of the second gear (5) is solid
Surely it is connected with objective table (10), is provided with micro slide (11) on the objective table (10), embedded with electricity in the micro slide (11)
Heater strip (21) is fixedly connected with bracket (12) on the pedestal (1), and the top of the bracket (12) is slidably fitted with slide bar
(17), the lower end of the slide bar (17) is equipped with hardometer (14), and the lower end of the hardometer (14) is equipped with test probe
(13), the side of the slide bar (17) is fixedly connected with rack gear (16), and the top of the bracket (12) is equipped with and rack gear (16)
The second adjusting knob (15) of transmission connection.
2. a kind of living cells hardness measuring device according to claim 1, it is characterised in that: the micro slide (11) it is upper
Portion opens up fluted (23), is equipped with temperature sensor (22) on the micro slide (11).
3. a kind of living cells hardness measuring device according to claim 1, it is characterised in that: opened up on the bracket (12)
Have slide opening (18), in slide opening (18), the side of second adjusting knob (15) is fixed to be connected for slide bar (17) sliding plug
It is connected to the shaft (19) through bracket (12), the third tooth for engaging connection with rack gear (16) is fixedly installed on the shaft (19)
It takes turns (20).
4. a kind of living cells hardness measuring device according to claim 1, it is characterised in that: test probe (13)
Lower end diameter is 10-20 microns.
5. a kind of living cells hardness measuring device according to claim 1, it is characterised in that: the upper end of the screw rod (2)
It is fixedly installed with the first adjusting knob (4), the width of the first gear (3) is greater than 2-3 times of width of second gear (5).
6. a kind of living cells hardness measuring device according to claim 1, it is characterised in that: the side of the column (7)
The reflective mirror (9) that cooperation microscope ontology (6) uses is installed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820659811.6U CN208206707U (en) | 2018-05-04 | 2018-05-04 | A kind of living cells hardness measuring device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820659811.6U CN208206707U (en) | 2018-05-04 | 2018-05-04 | A kind of living cells hardness measuring device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208206707U true CN208206707U (en) | 2018-12-07 |
Family
ID=64519648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820659811.6U Expired - Fee Related CN208206707U (en) | 2018-05-04 | 2018-05-04 | A kind of living cells hardness measuring device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208206707U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110954713A (en) * | 2019-12-23 | 2020-04-03 | 东北石油大学 | Atomic force microscope for observing displacement process of crude oil |
-
2018
- 2018-05-04 CN CN201820659811.6U patent/CN208206707U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110954713A (en) * | 2019-12-23 | 2020-04-03 | 东北石油大学 | Atomic force microscope for observing displacement process of crude oil |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20181207 Termination date: 20190504 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |