CN208114943U - Photon emits detection device and the boron neutron capture treatment system with it - Google Patents
Photon emits detection device and the boron neutron capture treatment system with it Download PDFInfo
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- CN208114943U CN208114943U CN201720523721.XU CN201720523721U CN208114943U CN 208114943 U CN208114943 U CN 208114943U CN 201720523721 U CN201720523721 U CN 201720523721U CN 208114943 U CN208114943 U CN 208114943U
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- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 title claims abstract description 48
- 229910052796 boron Inorganic materials 0.000 title claims abstract description 48
- 238000012360 testing method Methods 0.000 claims abstract description 152
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- 239000003814 drug Substances 0.000 claims abstract description 23
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- 229940079593 drug Drugs 0.000 claims abstract description 20
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 43
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Abstract
The application provides a kind of photon transmitting detection device and the boron neutron capture treatment system with it, including neutron capture therapeutic device, photon transmitting detection device and therapeutic bed, the neutron exposure boracic (10B) generate gamma ray after drug, the photon transmitting detection device include around the therapeutic bed periphery and to neutron exposure boracic (10B) the test section that the gamma ray generated after drug is detected, the test section includes the first test section and the second test section, first test section and the second test section can be away from each other or close to enable test section to be formed, radius increases or reduced annular, the annular are surrounded on the therapeutic bed.The application can change test section according to the actual conditions in the treatment of boron neutron capture for the photon transmitting detection device of boron neutron capture treatment system and be looped around the annular radius of shone thing, to improve the detection accuracy of the photon transmitting detection device.
Description
Technical field
The utility model relates in one aspect to a kind of medical instruments field more particularly to a kind of photon transmitting detection device;This
The another aspect of utility model is related to a kind of boron neutron capture treatment system, more particularly to a kind of with photon transmitting detection device
Boron neutron capture treatment system.
Background technique
Photon emission computed tomography is the advanced equipment of current nuclear medicine and imaging modality.Photon emits computer
Tomography includes single photon emission computed tomography (Single Photon Emission Computed
Tomography, abbreviation SPECT, single photon emission) and Positron Emission Computed Tomography (Positron Emission
Tomography, abbreviation PET, positron emission) by radioactive substance (such as99mTc,123I etc.) it marks in radiopharmaceutical (medicine
Object may be a kind of protein or organic molecule) on, labeled drug generally can selectively be absorbed by human body different parts, light
Son transmitting is utilized with the intracorporal Single Photon Emission nucleic of infusion of medicine people (such as99mTc,123I etc.) issue gamma-rays calculating
Machine assists lower reconstructed image, constitutes corresponding site fault image.For example, the drug that can be gathered in cardiac muscle is just used for the photon of heart
Transmitting imaging.These, which can be absorbed, indicates the organ of the drug of a certain amount of radioactive substance bright block can be presented in the picture, if device
Official has abnormal absorbing state to will lead to the partially bright of organs abnormality or partially dark.
And almost all of photon transmitting detection device belongs to rotating gamma-camera type at present, i.e., using being fixed on precision
High-quality gammacamera probe in endless glide, makes it rotate and acquire information around testee by computer drives,
Data processing is carried out by computer again, reconstructs the spatial image of checking matter, and press body axis is cross-section, sagittal is disconnected, it is coronal disconnected or
Arbitrary cross-section direction show the tomography of the object as.If consideration puts a set of photon in BNCT (treatment of boron neutron capture) room
Emit detection device, by make patient take boracic (10B) drug, and the neutron beam pair for generating neutron capture therapeutic device
Boracic (10B) drug is irradiated, and generates gamma-rays, and photon transmitting detection device is recycled to detect the gamma-rays of generation,
Because movable part has to less, and requires quick detection, and the rotation popped one's head in the prior art is wanted in neutron ray environment
Many movable accessories are asked to rotate probe, and speed of detection is slow, in order to overcome this problem, in the market often through using complete
Ring type photon emits detection device, avoids rotating all probes by rotating entire detection device to reduce movable accessory, but
It is that there are Railway Projects for this loopful formula photon transmitting detection device, for example, loopful formula photon emits detection device vulnerable to solid
Determine the influence of body positioning device, radius of investigation is fixed, and cannot be adjusted, can not be obtained more quasi- according to the actual state of patient
True positioning leads to not obtain more accurate information.
It is therefore desirable to improve to photon in the prior art transmitting detection device.
Utility model content
The one aspect of the utility model provides a kind of photon transmitting detection device, and the photon transmitting detection device includes
Test section and therapeutic bed, the test section include the first test section and the second test section positioned at the therapeutic bed two sides, institute
State the first test section and the second test section can away from each other or close to enable test section formed radius increase or
Reduced annular, the annular are surrounded on the therapeutic bed.It is capable of actual conditions (such as the different position of detected material as needed
Set and size) adjustment be looped around therapeutic bed periphery annular radius size, with improve photon transmitting detection device detection essence
Degree.
Further, the spy that can be rotated relative to therapeutic bed is mounted in first test section and the second test section
Device is surveyed, the test section detects the prompt gamma ray generated by the reaction of boron neutron capture by detection device.Described first
Detection device in test section and/or the second test section is preferably set to 180 degree relative to the maximum rotation angle of therapeutic bed,
Also other angles can be set into, such as 45 degree, 90 degree, 135 degree.Certainly, according to first test section and/or the second test section
It can be relative to a variety of freedom degrees that therapeutic bed is mobile but also rotates relative to therapeutic bed.Therefore, in some cases, which revolves
Gyration can be set to be more than 180 degree.
Further, photon transmitting detection device, which is connected with, is acquired the gamma ray that test section detects
Signal acquisition unit, using collected signal calculate boron (10B) computing unit of concentration and be connected to neutron capture treatment dress
Set and by calculated boron (10B) feedback unit of the concentration Real-time Feedback to neutron capture therapeutic device, the neutron capture treatment
Device, which is then connected with, to be shone according to the neutron beam that the signal pair capture therapeutic device that the feedback unit is fed back generates
Penetrate the amending unit that the time of tumour is modified.
Further, it is preferably carried out mode as one kind, the photon transmitting detection device further includes being located at therapeutic bed
The first support frame and the second support frame of two sides, first support frame include can ground moving the first pedestal, connection
In the first pedestal and along the vertical direction up and down flexible the first telescopic arm and positioned at first telescopic arm one end and
It is connected to the first adjutage of first test section, the first test section of institute is set to first adjutage, second support
Frame include can ground moving the second pedestal, be connected to the second pedestal and can along the vertical direction up and down flexible second
Telescopic arm and positioned at second telescopic arm one end and be connected to the second adjutage of the test section, second inspection
Survey portion is set to second adjutage, first support frame and the second support frame with the movement of the first pedestal and the second pedestal
Far from or close to therapeutic bed.
Further, when first telescopic arm is identical as the distance of stretch out and draw back of the second telescopic arm, first pedestal and
When two pedestals, first test section and the second test section contact with each other, first test section and the second detection
Portion forms the annular around therapeutic bed periphery maximum radius.
Further, when the distance of stretch out and draw back of first telescopic arm and the second telescopic arm difference, first pedestal and the
When two pedestals are close to each other, first test section and the second test section, which are formed, to be surrounded on the radius of the therapeutic bed periphery and subtracts
It is small.
Further, first test section and the second test section are able to rotate relative to therapeutic bed, so that first
Detection device in test section relative to detection device in the distance of therapeutic bed and the second test section relative to therapeutic bed away from
From consistent, to improve the accuracy and precision of the photon transmitting detection device in practical applications.
Further, rotating member is equipped between first telescopic arm and the first adjutage, the second telescopic arm and second prolongs
Rotating member is equipped between semi-girder, the first adjutage can rotate around rotating member and rotate the first test section relative to therapeutic bed, the
Two adjutages can rotate around rotating member and rotate the second test section relative to therapeutic bed.
The other side of the utility model provides a kind of boron neutron capture treatment system, and the boron neutron capture is controlled
Treatment system includes neutron capture therapeutic device, photon transmitting detection device and therapeutic bed, the neutron capture therapeutic device packet
Include the accelerator for generating charged particle beam, the neutron generating unit of generation neutron beam, centering after charged particle beam irradiation
Sub-beam carries out the beam-shaping body and collimator of shaping, and the beam-shaping body includes slow body and is coated on slow external all
Reflector, the slow body by from the neutron degradation that neutron generating unit generates to default power spectrum, what the reflector will deviate from
Neutron is led back to improve the neutron intensity in default power spectrum, and the collimator concentrates the neutron that neutron generating unit generates,
The neutron exposure boracic (10B gamma ray) is generated after drug, the photon transmitting detection device includes around the therapeutic bed
Periphery and to neutron exposure boracic (10B) the test section that the gamma ray generated after drug is detected, the test section include the
One test section and the second test section, first test section and the second test section can be away from each other or close to make to detect
Portion's formation radius can increase or reduced annular, the annular are surrounded on the therapeutic bed.Photon can be effectively improved
Emit detection device flexibility used in boron neutron capture treatment system.
Further, in order to realize test section to the complete detection of the irradiated body in therapeutic bed, first test section
Detection can be passed through relative to the detection device of therapeutic bed 180 degree rotation, the test section with being mounted in the second test section
Device realizes the detection to the prompt gamma ray generated by the reaction of boron neutron capture.First test section and/or the second inspection
Detection device in survey portion is preferably set to 180 degree relative to the maximum rotation angle of therapeutic bed, other also can be set into
Angle, such as 45 degree, 90 degree, 135 degree.It certainly, can be relative to therapeutic bed according to first test section and/or the second test section
The mobile a variety of freedom degrees that can be rotated again relative to therapeutic bed.Therefore, in some cases, which can be set to
More than 180 degree.
Further, first test section and the second test section are able to rotate relative to therapeutic bed, so that first
Detection device in test section relative to detection device in the distance of therapeutic bed and the second test section relative to therapeutic bed away from
From consistent, to improve the accuracy and precision of the photon transmitting detection device in practical applications.
In order to improve photon transmitting detection device flexibility used in entire boron neutron capture treatment system, the boron
Neutron capture treatment system can also include set on ground and positioned at the track of therapeutic bed two sides, first, second pedestal point
It is not installed on the track and movement on the track, the movement of first, second pedestal drives described first, second
Test section is close to each other or separate, so that the first test section and the second test section be made to be surrounded on the radius of the therapeutic bed periphery
Increase or reduces.It is, of course, also possible to which therapeutic bed setting can be formed in first test section and the second test section
Annular in the structure that is moved forward and backward to change the detection device and therapeutic bed or neutron capture therapeutic device and therapeutic bed
Relative position.
Compared with prior art, the application being capable of basis for the photon transmitting detection device of boron neutron capture treatment system
Actual conditions in the treatment of boron neutron capture change test section and are looped around the annular radius of shone thing, to improve the photon
Emit the detection accuracy of detection device.
Detailed description of the invention
Fig. 1 is the schematic diagram of boron neutron capture reaction;
Fig. 2 is10B(n,α)7Li neutron capture nuclear equation formula;
Fig. 3 is the schematic diagram of the neutron capture therapeutic device in the embodiment of the present application;
Fig. 4 is that the test section of the photon transmitting detection device in the embodiment of the present application is surrounded on therapeutic bed periphery maximum radius
When status diagram;
Fig. 5 is the schematic diagram of another angle of test section of the photon transmitting detection device in the embodiment of the present application;
Fig. 6 is that the test section of the photon transmitting detection device in the embodiment of the present application is surrounded on the reduction of therapeutic bed peripheral radius
Status diagram afterwards;
Fig. 7 is the module diagram of photon the transmitting detection device and neutron capture therapeutic device in the embodiment of the present application.
Specific embodiment
Neutron capture treatment as a kind of effective treating cancer means in recent years using gradually increasing, wherein with boron
Neutron capture treatment is most commonly seen, and the neutron of supply boron neutron capture treatment can be supplied by nuclear reactor or accelerator.In boron
Son capture treatment (Boron Neutron Capture Therapy, BNCT) be using boracic (10B) drug has thermal neutron
The characteristic of high capture cross section, by10B(n,α)7Li neutron capture and nuclear fission reaction generate4He and7Two heavy burden charged particle of Li,
Meanwhile neutron and boracic (10B the gamma ray generated after) drug reacts.Referring to Figures 1 and 2, which respectively show in boron
The schematic diagram of sub- capture reaction and10B(n,α)7Li neutron capture nuclear equation formula, the average energy of two charged particles are about
There is 2.33MeV High Linear to shift (Linear Energy Transfer, LET), short range feature, the linear energy of α particle
Transfer and range are respectively 150keV/ μm, 8 μm, and7Li heavy burden particle is then 175keV/ μm, 5 μm, and the integrated range of two particle is about
It is equivalent to a cell size, therefore the radiation injury for caused by organism can be confined to cell level, when boracic drug selects
It is gathered in tumour cell to selecting property, neutron appropriate of arranging in pairs or groups penetrates source, just can be before not normal tissue causes too major injury
It puts, achievees the purpose that tumour cell is killed in part.
This application discloses a kind of photons applied in boron neutron capture treatment system to emit detection device, the photon
Transmitting detection device be used for detect neutron capture therapeutic device generation neutron beam and boracic (10B it is produced after) drug reacts
Raw gamma ray, thus by gamma ray calculate boron (10B concentration).
Below in conjunction with attached drawing, the specific photon being applied in boron neutron capture treatment system of introducing emits detection device.
As shown in figure 3, the boron neutron capture treatment system includes neutron capture therapeutic device 100, photon transmitting detection
Device 200 and therapeutic bed 300.The neutron capture therapeutic device 100 includes the accelerator for generating charged particle beam
101, the beam for generating the neutron generating unit 102 of neutron beam N after charged particle beam P irradiation, carrying out shaping to neutron beam N
Shaping body 103 and collimator 104.The beam-shaping body 103 is including slow body 105 and is coated on the anti-of slow 104 periphery of body
Beam 106, the slow body 105 is by from the neutron degradation that neutron generating unit 102 generates to default power spectrum, the reflector 106
The neutron that will deviate from is led back to improve the neutron intensity in default power spectrum, what the collimator 104 generated neutron generating unit 102
Neutron is concentrated.
Patient take or inject boracic (10B) after drug, boracic (10B it is gathered in tumour cell to drug selectivity),
The neutron exposure to boracic (10B gamma ray) is generated after drug, the photon transmitting detection device carries out the gamma ray
Detection.
As shown in Figures 4 to 6, the photon transmitting detection device 200 includes the test section around the therapeutic bed periphery
201, the test section 201 includes the first test section 202 and the second test section 203, and first test section 202 and second detects
Portion 203 can away from each other or close to increasing to the annular radius that enables test section to be formed in 300 periphery of therapeutic bed or
Person reduces.The first test section 202 and second can be distributed in by being mounted in first test section 202, the second test section 203
Detection device 204 in test section 203 relative to the rotation of therapeutic bed 180 degree, the test section 201 are real by detection device 204
Now to the detection of the gamma ray.
As a preferred embodiment, first test section 202 and the second test section 203 are each other in the application
Between far from or close to being to be accomplished by the following way.
The photon transmitting detection device 200 further includes the first support frame 211 and second positioned at 300 two sides of therapeutic bed
Support 221.First support frame 211 include can ground moving the first pedestal 212, be connected to the first pedestal 212
First telescopic arm 213 and positioned at first telescopic arm 213 one end and be connected to the first of first test section 202
Adjutage 214.First telescopic arm 213 can be flexible up and down along the vertical direction, and the first test section 202 of institute is set to described first
Adjutage 214, first test section 202 and first adjutage 214 with the first telescopic arm 213 stretching motion up and down
And it moves up and down.Second support frame 221 include can ground moving the second pedestal 222, be connected to the second pedestal 222
The second telescopic arm 223 and positioned at second telescopic arm 223 one end and be connected to the of second test section 203
Two adjutages 224, second telescopic arm 223 can be flexible up and down along the vertical direction, and second test section 203 is set to described
Second adjutage 224, second test section 203 and the second adjutage 224 with the stretching motion up and down of the second telescopic arm 223 and
It moves up and down.First support frame 211 and the second support frame 221 are remote with the movement of the first pedestal 212 and the second pedestal 222
From or close to therapeutic bed 300.For the ease of manufacture, as a preferred embodiment, first support frame 211 and the
The structure of two support frames 221 is identical.Furthermore it is possible to which first telescopic arm 213 and the second telescopic arm 223 are set as to stretch
The structure of contracting, and be configured to first adjutage 214 and the second adjutage 224 to be respectively relative to described first to stretch
The structure of arm 213 and the rotation of the second telescopic arm 223 changes 201 ring of test section by rotating the first, second adjutage 213,223
It is wound on the radius of 300 periphery of therapeutic bed.Certainly, the rotational structure of first adjutage 214 and the second adjutage 224 with
And the stretching structure of first telescopic arm 213 and the second telescopic arm 223 can use simultaneously, to increase the test section 201
Freedom degree.
It is preferably carried out mode as one kind, between the first telescopic arm 213 described herein and the first adjutage 214 also
Equipped with rotating member 30.That is, the first adjutage 214 can be rotated around rotating member 30 relative to the first telescopic arm 213;Second stretches
Be again provided with rotating member 30 between contracting arm 223 and the second adjutage 224, the second adjutage 224 can around rotating member 30 relative to
The rotation of second telescopic arm 223.The advantage of doing so is that detection can be changed by rotating the first, second adjutage 213,223
Portion 201 is looped around the radius of 300 periphery of therapeutic bed, while can further increase the freedom degree of entire detection device 204,
Adjust the distance of the first test section 201 and the second test section 202 relative to knub position, that is, the first inspection of adjustment can be conducive to
Survey portion 201 relative to knub position distance and the second test section 202 relative to consistent at a distance from knub position, to improve whole
The detection accuracy of a detection device 204.
In the actually detected course of work, the knub position of different patients is likely to difference, for example, some patients' is swollen
Tumor is on head, and the tumour of some patients is in chest, if the tumor locus that the patient in therapeutic bed is detected is head,
So, the first test section 202 and the second test section 203 be looped around the annular radius of 300 periphery of therapeutic bed be then it is smaller preferably, and
The tumor locus detected if necessary is chest, then, according to actual measurement demand, change first test section and the
Two test sections are looped around the radius of the annular of therapeutic bed periphery stroke.Because test section is looped around the annular radius of therapeutic bed periphery
Smaller, the detection device 204 installed in test section 201 could be closer to patient, and detection device 204 is relative to patient tumors
The detection range at position reduces, and the relevant information detected just can be more, the detection accuracy of entire photon transmitting detection device 200
Just can more it increase.
When need to reduce be looped around the annular radius of 300 periphery of therapeutic bed when, change the first telescopic arm 213 or second stretch
The collapsing length of contracting arm 223 keeps the collapsing length of the first telescopic arm 213 and the second telescopic arm 223 inconsistent, also, mobile the
One pedestal 212 and the second pedestal 222 keep the first pedestal 212 and the second pedestal 222 close to each other, the first test section 202 and second
The radius that test section 203 is looped around patient tumors periphery then reduces (distance of detection device 204 to knub position reduces);When need
When increasing the annular radius for being looped around 300 periphery of therapeutic bed, the flexible of the first telescopic arm 213 and the second telescopic arm 223 is kept
Distance is consistent, and mobile first pedestal 212 and the second pedestal 222 are located remotely from each other the first pedestal 212 and the second pedestal 222, the
The radius that one test section 202 and the second test section 203 are looped around patient chest periphery then increases.When first telescopic arm 213
It is identical as the distance of stretch out and draw back of the second telescopic arm 223, first pedestal 211 and the second pedestal 221 are moved to first detection
When portion 202 and the second test section 203 contact with each other, first test section 202 and the formation of the second test section 203 are surrounded on described
The annular of 300 periphery maximum radius of therapeutic bed.
The movement of first pedestal 212 and the second pedestal 222 can be realized by the way that track 230 is arranged on ground.Specifically
Ground can be pacified respectively by the track 230 in ground setting positioned at 300 two sides of therapeutic bed, first, second pedestal 212,222
Movement loaded on the track 230 and on the track 230, described in the movement of first, second pedestal 212,222 drives
First, second test section 202,203 is close to each other or separate, so that the first test section 202 and the second test section 203 be made to surround
Radius in 300 periphery of therapeutic bed increases or reduces.
In the present embodiment, the therapeutic bed 300 can be in 203 shape of first test section 202 and the second test section
At annular in be moved forward and backward relative position (i.e. change detection device to change the detection device 204 with therapeutic bed 300
204 with the relative position of tumour).Because therapeutic bed 300 can be moved forward and backward, only need to be set as being located at by track 230
300 two sides of therapeutic bed and the structure that can extend along the direction vertical with 300 direction of motion of therapeutic bed, the
One, the second pedestal 211,221 is mounted on the track 230 and moves along the track 230 to separate or close institute
State therapeutic bed 300.
Because during the radius that the test section 201 is looped around 300 periphery of therapeutic bed can be according to actual therapeutic
The actual size of patient tumors position is changed, and therapeutic bed 300 can also be carried out according to the actual conditions of patient tumors position
Movement, to make patient tumors position be between test section 201, so entire photon transmitting detection device 200 and therapeutic bed
300 cooperations can be realized the comprehensive detection to patient tumors.
After the completion of the treatment of boron neutron capture, mobile first pedestal 211 and the second pedestal 221, so that entire photon
Transmitting detection device 200 is divided into two parts and far from therapeutic bed 300.
In conjunction with Fig. 7, photon transmitting detection device 200 be also connected with gamma ray that test section 201 is detected into
Row acquisition signal acquisition unit 240, using collected signal calculating boron concentration computing unit 250 and be connected to neutron
Capture therapeutic device 100 and by the feedback unit 260 of calculated boron concentration Real-time Feedback to neutron capture therapeutic device 100,
The neutron capture therapeutic device 100 is then connected with can be according to the signal pair capture treatment dress that feedback unit 260 is fed back
Set the amending unit 270 that the neutron beam of 100 generations is modified tumour irradiation time.
Now photon transmitting detection device is described in the course of work of entire boron neutron capture treatment system.
Firstly, patient inject (taking) containing boron (10B) drug is placed in the therapeutic bed 300, the boracic (10B) medicine
Object is assembled at patient tumors position;
The photon transmitting detection device 200 is sequentially adjusted in therapeutic bed 300 relative to detection according to the position of patient tumors
The position in portion 201 (makes tumor locus be located at the correspondence position of detection device 204 in test section 201 by the movement of therapeutic bed 300
Set) and test section 201 the first test section 202 and the second test section 203 be looped around the annular radius of 300 periphery of therapeutic bed;
The neutron capture therapeutic device 100 generates neutron beam N, and the neutron beam N has boracic to patients congregate
(10B) knub position of drug is irradiated, neutron beam N and boron (10B gamma ray) is generated;
First test section 202 and the second test section 203 by detection device 204 detect neutron beam N and boron (10B)
Generate gamma ray;
The signal acquisition unit 240 acquires the gamma ray detected, and it is collected to utilize computing unit 250 to pass through
Gamma ray calculate boron (10B) concentration;
The feedback unit 260 by calculated boron (10B) concentration feedback is to neutron capture therapeutic device 100;
The neutron capture therapeutic device 100 by amending unit 270, the boron that is fed back according to feedback unit 260 (10B) dense
Degree is modified the irradiation time of neutron beam.
After entire therapeutic process, photon transmitting detection device 200 can be divided into two parts and be moved to far
Position from neutron capture therapeutic device 100 emits 200 phase of detection device to reduce neutron capture therapeutic device 100 with photon
Radiation effect between mutually.
The photon transmitting detection device for boron neutron capture treatment system that the application discloses is not limited to the above reality
Apply structure represented by content described in example and attached drawing.And it is filled if it is desirable, can also be imaged to other tomoscans
Set (such as Computed Tomography:CT, CT scan) carry out the application in improvement.In the application
On the basis of apparently change, substitution or modification that the material and shape of wherein component and position are made, all in this Shen
Within the scope of please being claimed.
Claims (8)
1. a kind of photon emits detection device, it is characterised in that:The photon transmitting detection device includes test section and treatment
Bed, the test section include the first test section and the second test section positioned at the therapeutic bed two sides, first test section and
Second test section can increase or reduced annular away from each other or close to enable test section to form radius, described
Annular is surrounded on the therapeutic bed, and being mounted in first test section and the second test section can rotate relative to therapeutic bed
Detection device, the test section by detection device detect by boron neutron capture reaction generate prompt gamma ray, it is described
Photon transmitting detection device further includes the first support frame and the second support frame positioned at therapeutic bed two sides, the first support frame packet
Include can ground moving the first pedestal, be connected to the first pedestal and along the vertical direction up and down flexible the first telescopic arm with
And positioned at first telescopic arm one end and be connected to the first adjutage of first test section, first test section
Set on first adjutage, second support frame include can ground moving the second pedestal, be connected to the second pedestal
And can along the vertical direction up and down flexible the second telescopic arm and positioned at second telescopic arm one end and be connected to
Second adjutage of the test section, second test section are set to second adjutage, first support frame and second
Support frame moves away from or with the first pedestal and the second pedestal close to therapeutic bed.
2. photon according to claim 1 emits detection device, it is characterised in that:When first telescopic arm is stretched with second
The distance of stretch out and draw back of contracting arm is identical, first pedestal and the second pedestal first test section and the second test section
When contacting with each other, first test section and the second test section form the annular around therapeutic bed periphery maximum radius;When
The distance of stretch out and draw back of first telescopic arm and the second telescopic arm is different, when first pedestal and the second pedestal close to each other, institute
It states the first test section and the second test section forms the radius reduction for being surrounded on the therapeutic bed periphery.
3. photon according to claim 1 emits detection device, it is characterised in that:First test section and/or second
Test section can be rotated relative to therapeutic bed.
4. photon according to claim 3 emits detection device, it is characterised in that:First telescopic arm and first extends
It is equipped with rotating member between arm, rotating member is equipped between the second telescopic arm and the second adjutage, the first adjutage can be around rotating member
It rotates and rotates the first test section relative to therapeutic bed, the second adjutage can rotate around rotating member and keep the second test section opposite
It is rotated in therapeutic bed.
5. a kind of boron neutron capture treatment system, it is characterised in that:The boron neutron capture treatment system includes that neutron capture is controlled
Device, photon transmitting detection device and therapeutic bed are treated, the neutron capture therapeutic device includes for generating charged particle beam
Accelerator, after charged particle beam irradiation generate neutron beam neutron generating unit, to neutron beam carry out shaping beam
Shaping body and collimator, the beam-shaping body include slow body and the reflector for being coated on slow external week, the slow body
By from the neutron degradation that neutron generating unit generates to default power spectrum, the neutron that the reflector will deviate from is led back to improve default energy
Neutron intensity in spectrum, the collimator concentrate the neutron that neutron generating unit generates, the neutron exposure boracic drug
After generate gamma ray, the photon transmitting detection device includes around the therapeutic bed periphery and to neutron exposure boracic drug
The test section that the gamma ray generated afterwards is detected, the test section include the first test section and the second test section, and described the
One test section and the second test section can increase or reduce away from each other or close to enable test section to form radius
Annular, the annular is surrounded on the therapeutic bed.
6. boron neutron capture treatment system according to claim 5, it is characterised in that:First test section and the second inspection
The detection device that can be rotated relative to therapeutic bed is mounted in survey portion, the test section is realized by detection device to described
The detection of gamma ray.
7. boron neutron capture treatment system according to claim 5, it is characterised in that:First test section and/or
Two test sections can be rotated relative to therapeutic bed, so that distance and the of the detection device in the first test section relative to therapeutic bed
Detection device in two test sections is consistent relative to the distance of therapeutic bed.
8. boron neutron capture treatment system according to claim 5, it is characterised in that:The photon transmitting detection device connects
It is connected to the signal acquisition unit being acquired to the gamma ray that test section detects, utilizes collected signal calculating boron concentration
Computing unit and be connected to neutron capture therapeutic device and by calculated boron concentration Real-time Feedback to neutron capture treat
The feedback unit of device, the neutron capture therapeutic device are then connected with the signal pair that can be fed back according to the feedback unit
The amending unit that the time for the neutron beam irradiation tumour that son capture therapeutic device generates is modified.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
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CN201720523721.XU CN208114943U (en) | 2017-05-12 | 2017-05-12 | Photon emits detection device and the boron neutron capture treatment system with it |
EP17909188.9A EP3583981B1 (en) | 2017-05-12 | 2017-07-13 | Photon emission detection device and boron neutron capture therapy system having same |
PCT/CN2017/092733 WO2018205403A1 (en) | 2017-05-12 | 2017-07-13 | Photon emission detection device and boron neutron capture therapy system having same |
JP2020500940A JP6938757B2 (en) | 2017-05-12 | 2017-07-13 | Photon emission detector and boron neutron capture therapy system with it |
US16/553,380 US11400314B2 (en) | 2017-05-12 | 2019-08-28 | Photon emission detection device and neutron capture therapy system with the same |
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CN201720523721.XU CN208114943U (en) | 2017-05-12 | 2017-05-12 | Photon emits detection device and the boron neutron capture treatment system with it |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108853751A (en) * | 2017-05-12 | 2018-11-23 | 南京中硼联康医疗科技有限公司 | Photon emits detection device and the boron neutron capture treatment system with it |
CN111836448A (en) * | 2019-04-15 | 2020-10-27 | 禾荣科技股份有限公司 | Minimally invasive neutron beam generation device and minimally invasive neutron capture treatment system |
-
2017
- 2017-05-12 CN CN201720523721.XU patent/CN208114943U/en not_active Withdrawn - After Issue
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108853751A (en) * | 2017-05-12 | 2018-11-23 | 南京中硼联康医疗科技有限公司 | Photon emits detection device and the boron neutron capture treatment system with it |
CN108853751B (en) * | 2017-05-12 | 2024-05-17 | 南京中硼联康医疗科技有限公司 | Photon emission detection device and boron neutron capture treatment system with same |
CN111836448A (en) * | 2019-04-15 | 2020-10-27 | 禾荣科技股份有限公司 | Minimally invasive neutron beam generation device and minimally invasive neutron capture treatment system |
CN111836448B (en) * | 2019-04-15 | 2022-10-04 | 禾荣科技股份有限公司 | Minimally invasive neutron beam generation device and minimally invasive neutron capture treatment system |
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