CN208038430U - A kind of viral purification device - Google Patents
A kind of viral purification device Download PDFInfo
- Publication number
- CN208038430U CN208038430U CN201820274592.XU CN201820274592U CN208038430U CN 208038430 U CN208038430 U CN 208038430U CN 201820274592 U CN201820274592 U CN 201820274592U CN 208038430 U CN208038430 U CN 208038430U
- Authority
- CN
- China
- Prior art keywords
- purifying
- chamber
- consummateization
- ultra micro
- thick
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000746 purification Methods 0.000 title claims abstract description 13
- 230000003612 virological effect Effects 0.000 title claims abstract description 10
- 238000010438 heat treatment Methods 0.000 claims abstract description 7
- 239000007788 liquid Substances 0.000 claims description 16
- 238000000197 pyrolysis Methods 0.000 claims description 11
- 241000700605 Viruses Species 0.000 claims description 3
- 239000012634 fragment Substances 0.000 claims description 3
- 239000012535 impurity Substances 0.000 claims description 3
- 102000004169 proteins and genes Human genes 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 239000002504 physiological saline solution Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 description 4
- PNEYBMLMFCGWSK-UHFFFAOYSA-N Alumina Chemical compound [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 3
- 238000000034 method Methods 0.000 description 2
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004695 Polyether sulfone Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000003670 easy-to-clean Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229910000449 hafnium oxide Inorganic materials 0.000 description 1
- WIHZLLGSGQNAGK-UHFFFAOYSA-N hafnium(4+);oxygen(2-) Chemical compound [O-2].[O-2].[Hf+4] WIHZLLGSGQNAGK-UHFFFAOYSA-N 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 239000011147 inorganic material Substances 0.000 description 1
- 229910052809 inorganic oxide Inorganic materials 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 229920000620 organic polymer Polymers 0.000 description 1
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 description 1
- IVXQBCUBSIPQGU-UHFFFAOYSA-N piperazine-1-carboxamide Chemical compound NC(=O)N1CCNCC1 IVXQBCUBSIPQGU-UHFFFAOYSA-N 0.000 description 1
- 229920002492 poly(sulfone) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920006393 polyether sulfone Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 229910001928 zirconium oxide Inorganic materials 0.000 description 1
Abstract
The utility model is related to a kind of viral purification devices, including：Thick purifying chamber, consummateization chamber, ultra micro purifying chamber, the first kinetic pump, the second kinetic pump, the first bearing, second bearing, thick purifying filter screen is installed in the thick purifying cavity, consummateization filter screen is installed in the consummateization cavity, it is offered on consummateization cavity portion of upper body and consummate dissolves into mouth, lower body be provided with it is consummate dissolve mouth, ultrapureization filter screen, purifying outlet and heating device are installed in the ultra micro purifying cavity；The utility model purifies precision height, at low cost, while improving purification quality and efficiency.
Description
Technical field
The utility model belongs to biomedical sector, is suitable for a kind of viral purification device.
Background technology
The purifying of virus, purification technique are more and more common in current biotechnology, and previous purifier apparatus is five flowers
Eight, some uses chemical-agent technique using supercentrifugal process, some, and most equipment price is expensive, inconvenient for operation, purifying is imitated
Rate is also general；Purifier apparatus purification efficiency is low, rejection is low and viral loss is big.With the development of biotechnology, correlation is matched
Complete equipment must also continue to develop, and to adapt to the situation of current high speed development, a kind of efficient, simple, cheap purifying be needed to fill
It sets.
Utility model content
The purpose of this utility model is in view of the deficiencies of the prior art, to provide a kind of viral purification device, including slightly purify
Chamber, consummateization chamber, ultra micro purifying chamber, the first kinetic pump, the second kinetic pump, the first bearing, the second bearing, it is characterised in that：
Thick purifying intracavitary is equipped with thick purifying filter screen, for removing the abiotic impurity in cell pyrolysis liquid；It will be thick pure
Change chamber and be divided into upper and lower part, thick purify offers purifying entrance, thick purifying outlet on chamber lower part；
Consummateization intracavitary is equipped with consummateization filter screen, for removing cell fragment in the cell pyrolysis liquid；It will be consummate
Change chamber and be divided into upper and lower part, offered on consummateization chamber top it is consummate dissolve into mouth, lower part, which is provided with, consummate dissolves mouth；
Ultra micro purifying intracavitary is equipped with ultrapureization filter screen, purifying outlet and heating device；Ultrapureization filter screen is for going
Except the protein molecule in cell pyrolysis liquid；
First kinetic pump is mounted on the first bearing, and the first kinetic pump is connected to by first passage with thick purifying chamber top,
First kinetic pump is connected to by second channel with thick purifying chamber lower part, and the first kinetic pump passes through third channel and consummateization chamber lower part
Connection；
Second kinetic pump is connected to by fourth lane with consummateization chamber top, the second kinetic pump by Five-channel with it is consummate
Change the connection of chamber lower part, the second kinetic pump purifies chamber cavity with ultra micro by the 6th channel and is connected to；Ultra micro purifying chamber cavity is mounted on
On second bearing；
First kinetic pump will pump to thick purifying chamber top progress mistake three times by purifying the cell pyrolysis liquid that entrance is added
Then filtered first mixing liquid is pumped to ultra micro and purifies intracavitary by filter, the second kinetic pump will be purified by ultra micro on chamber
The physiological saline that portion is added pumps to thick purifying chamber top with the mixed liquor sent from thick purifying chamber and is filtered three times, then will
Filtered second mixing liquid pumps in ultra micro purifying chamber, and the second mixed liquor of heating device pair that ultra micro purifies intracavitary carries out
Heating, hydrone purify the ultrapureization filter screen that intracavitary is arranged by ultra micro and evaporate into air, so that virus is stayed in the cavity, shape
At the third mixed liquor of purifying, the purifying outlet on chamber is purified by ultra micro and is dispensed.
The utility model has the beneficial effects that：It is high to purify precision, it is at low cost, while improving purification quality and efficiency.
Description of the drawings
Fig. 1 is a kind of structure chart of viral purification device of the utility model；
Specific implementation mode
The embodiments of the present invention are illustrated below in conjunction with attached drawing, it should be understood that embodiment described herein
It is only used for describing and explaining the present invention, is not used to limit the utility model.
Such as, a kind of viral purification device, can effectively solve the problems in background technology.
To achieve the above object, the technical scheme adopted by the utility model is that：A kind of viral purification device, including slightly purify
Chamber, consummateization chamber, ultra micro purifying chamber, the first kinetic pump, the second kinetic pump, the first bearing, the second bearing, it is characterised in that：Slightly
Purifying intracavitary is equipped with thick purifying filter screen, for removing the abiotic impurity in cell pyrolysis liquid；Thick purifying chamber is divided into
Portion and lower part, thick purify offer purifying entrance, thick purifying outlet on chamber lower part；Consummateization intracavitary is equipped with consummateization filtering
Net, for removing cell fragment in the cell pyrolysis liquid；Consummateization chamber is divided into upper and lower part, consummateization chamber is opened on top
Mouth is dissolved into equipped with consummate, and lower part, which is provided with, consummate dissolves mouth；Ultra micro purifying intracavitary is equipped with ultrapureization filter screen, purifying outlet and
Heating device；Ultrapureization filter screen is used to remove the protein molecule in cell pyrolysis liquid；
Thick purifying filter screen, consummateization filter screen and ultrapureization filter screen detachable structure, easy to clean and replacement；Its point
From material can be organic film material can also be inorganic material film.Include mainly ceramic material, metal material and organic high score
Sub- material.Wherein organic polymer mainly has cellulose acetate, sulfonated polysulfone, sulfonated polyether sulfone, polyamide, polyvinyl alcohol or poly-
Piperazine amide；Inorganic oxide material mainly has aluminium oxide, titanium oxide, zirconium oxide and hafnium oxide；
First kinetic pump is mounted on the first bearing, and the first kinetic pump is connected to by first passage with thick purifying chamber top,
First kinetic pump is connected to by second channel with thick purifying chamber lower part, and the first kinetic pump passes through third channel and consummateization chamber lower part
Connection；Second kinetic pump is connected to by fourth lane with consummateization chamber top, and the second kinetic pump passes through Five-channel and consummateization
Chamber lower part is connected to, and the second kinetic pump purifies chamber cavity with ultra micro by the 6th channel and is connected to；Ultra micro purifies chamber cavity and is mounted on the
On two bearings；
First passage, third channel, fourth lane, Five-channel, is equipped with observation on the 6th channel and regards second channel
Mirror, for observing the state of liquid in channel.
Claims (1)
1. a kind of viral purification device, including slightly purify chamber, consummateization chamber, ultra micro purifying chamber, the first kinetic pump, the second power
Pump, the first bearing, the second bearing, it is characterised in that：
The thick purifying intracavitary is equipped with thick purifying filter screen, for removing the abiotic impurity in cell pyrolysis liquid；It will be thick pure
Change chamber and be divided into upper and lower part, thick purify offers purifying entrance, thick purifying outlet on chamber lower part；
The consummateization intracavitary is equipped with consummateization filter screen, for removing cell fragment in the cell pyrolysis liquid；It will be described
Consummateization chamber is divided into upper and lower part, offered on consummateization chamber top it is consummate dissolve into mouth, lower part is provided with consummate dissolve
Mouthful；
The ultra micro purifying intracavitary is equipped with ultrapureization filter screen, purifying outlet and heating device；The ultrapureization filter screen is used
Protein molecule in the removal cell pyrolysis liquid；
First kinetic pump is mounted on first bearing, and first kinetic pump passes through first passage and the thick purifying
Chamber top is connected to, and first kinetic pump is connected to by second channel with the thick purifying chamber lower part, and first kinetic pump is logical
Third channel is crossed to be connected to consummateization chamber lower part；
Second kinetic pump is connected to by fourth lane with consummateization chamber top, and second kinetic pump is logical by the 5th
Road is connected to consummateization chamber lower part, and second kinetic pump purifies chamber cavity with the ultra micro by the 6th channel and is connected to；
The ultra micro purifying chamber cavity is mounted on second bearing；
First kinetic pump pumps to the cell pyrolysis liquid being added by the purifying entrance on the thick purifying chamber
Portion is filtered three times, and filtered first mixing liquid, which is then pumped to the ultra micro, purifies intracavitary, second power
Pump will purify the physiological saline that chamber top is added by the ultra micro and pump to institute with the mixed liquor sent from the thick purifying chamber
It states thick purifying chamber top to be filtered three times, then pumps to filtered second mixing liquid in the ultra micro purifying chamber,
The second mixed liquor of heating device pair of the ultra micro purifying intracavitary heats, and hydrone purifies intracavitary by the ultra micro and is arranged
The ultrapureization filter screen evaporate into air, so that virus is stayed the third mixed liquor for forming purifying in the cavity, pass through ultra micro
Purifying outlet on purifying chamber is dispensed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820274592.XU CN208038430U (en) | 2018-02-27 | 2018-02-27 | A kind of viral purification device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820274592.XU CN208038430U (en) | 2018-02-27 | 2018-02-27 | A kind of viral purification device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208038430U true CN208038430U (en) | 2018-11-02 |
Family
ID=63950137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820274592.XU Expired - Fee Related CN208038430U (en) | 2018-02-27 | 2018-02-27 | A kind of viral purification device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208038430U (en) |
-
2018
- 2018-02-27 CN CN201820274592.XU patent/CN208038430U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20181102 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |