CN207918816U - A kind of multidirectional migration experiment device of cell - Google Patents
A kind of multidirectional migration experiment device of cell Download PDFInfo
- Publication number
- CN207918816U CN207918816U CN201820182926.0U CN201820182926U CN207918816U CN 207918816 U CN207918816 U CN 207918816U CN 201820182926 U CN201820182926 U CN 201820182926U CN 207918816 U CN207918816 U CN 207918816U
- Authority
- CN
- China
- Prior art keywords
- cell
- bottom plate
- groove
- plate
- migration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a kind of multidirectional migration experiment devices of cell, including bottom plate, cellular compartments plate is angularly equipped on the bottom plate, the bottom plate is divided into four test blocks by cellular compartments plate, it is equipped with cell at the center of the bottom plate and places blind hole, one end of the cellular compartments plate is connected to cell and places on the side wall of blind hole, the other end of the cellular compartments plate is connected on the madial wall of bottom plate, four cell migration grooves are angularly equipped on the bottom plate, the cell places blind hole equipped with the through-hole with cell migration groove match.The utility model operation simple in structure is easy, pass through worm gear, baffle, telescopic rod, the first mounting groove, carriage, worm screw and the isostructural interaction of reserved cavity, vibration can not be will produce when experimental provision movement is put down, to avoid cell from influencing cell migration because of vibration, the accuracy for influencing experimental data is avoided.
Description
Technical field
The utility model is related to ventilation blower technical field more particularly to a kind of multidirectional migration experiment devices of cell.
Background technology
Cell migration generally existing in the normal physiological activity and disease of human body occur, such as the looking for food of cell, wound
Many events such as wound healing, embryo's generation, nervous system formation, immune response, cancer metastasis are directed to cell migration.Mesh
Scratch experiment is mainly used in preceding research cell migration.Epithelial cell, horn cell etc. form single layer or cladding under physiological status
Epithelium, under the pathological states such as wound healing, cell migrates, based on lateral movement.The fine simulation of scratch experiment
This forms of motion, and it is easy to operate, therefore be a good model for studying cell migration, existing research cell moves
It needs experimental provision being moved to suitable position during shifting and observe, but hold when putting down experimental provision
Easily and testing stand collision generates vibration, to affect the travel motion of cell, affects test data.
Utility model content
Purpose of the utility model is to solve disadvantages existing in the prior art, such as：Study the process of cell migration
In need experimental provision being moved to suitable position and observe, but be easy and test when putting down experimental provision
Platform collision generates vibration, to affect the travel motion of cell, affects test data.
To achieve the goals above, the utility model uses following technical solution：
A kind of multidirectional migration experiment device of cell, including bottom plate are angularly equipped with cellular compartments plate, institute on the bottom plate
It states bottom plate and four test blocks is divided by cellular compartments plate, cell is equipped at the center of the bottom plate and places blind hole, it is described thin
One end of born of the same parents' demarcation strip is connected to cell and places on the side wall of blind hole, and the other end of the cellular compartments plate is connected to the interior of bottom plate
On side wall, four cell migration grooves are angularly equipped on the bottom plate, the cell placement blind hole is equipped with and cell migration
One end of the through-hole of groove match, the cell migration groove is connected to the side wall that cell places blind hole by through-hole, described thin
The other end that born of the same parents migrate groove is connected with cell migration blind hole, and the cell migration groove and cell migration blind hole are respectively positioned on experiment
In area, movable block is arranged on two lateral walls of the bottom plate, the both sides of the bottom plate are also arranged with mounting plate, the peace
The first mounting groove is equipped in loading board, one end of the mounting plate is interspersed with rotating bar, and one end of the rotating bar is equipped with rotation handle
The other end of hand, the rotating bar passes through the side wall of mounting plate and is arranged with worm gear, and the side engagement of the worm gear is connected with snail
Bar, the top activity of the worm screw are inserted in the inner top of mounting plate, baffle, the baffle are connected on first mounting groove
It is equipped with loose slot, one end of the movable block passes through loose slot and is equipped with carriage, and the movable block passes through carriage
It is connected on the side wall of the first mounting groove, reserved cavity is equipped between the movable block and worm screw, the side of the movable block connects
It is connected to telescopic rod, the other end of the telescopic rod is connected on the side wall of the first mounting groove, and spring is arranged on the telescopic rod.
Preferably, it is equipped with the second mounting groove on four madial walls of the bottom plate, is connected in second mounting groove
Thermal insulation board.
Preferably, the carriage includes groove, and the groove is located at one end of movable block, fixed in the groove to connect
It is connected to fixed link, pulley is rotatably connected in the fixed link.
Preferably, rubber pad is wrapped on the rotating handles, the rubber pad is equipped with anti-skid chequer.
Preferably, the movable block and bottom plate are integrally formed.
Compared with prior art, the utility model has the beneficial effects that：It is simple in structure operation be easy, by worm gear, baffle,
Telescopic rod, the first mounting groove, carriage, worm screw and the isostructural interaction of reserved cavity, can move in experimental provision
It is dynamic not will produce vibration when put down, to avoid cell from influencing cell migration because of vibration, avoid influence experimental data
Accuracy.
Description of the drawings
Fig. 1 be the utility model proposes a kind of cell it is multidirectional migration experiment device overlooking structure diagram；
Fig. 2 be the utility model proposes a kind of cell it is multidirectional migration experiment device positive structure diagram.
In figure：1 bottom plate, 2 cell migration blind holes, 3 cell migration grooves, 4 cells place blind hole, 5 test blocks, 6 movable blocks,
7 mounting plates, 8 rotating bars, 9 cellular compartments plates, 10 worm gears, 11 baffles, 12 telescopic rods, 13 first mounting grooves, 14 carriages, 15
Worm screw, 16 reserved cavitys.
Specific implementation mode
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.
In the description of the present invention, it should be understood that term "upper", "lower", "front", "rear", "left", "right",
The orientation or positional relationship of the instructions such as "top", "bottom", "inner", "outside" is to be based on the orientation or positional relationship shown in the drawings, and is only
The utility model and simplifying describes for ease of description, do not indicate or imply the indicated device or element must have it is specific
Orientation, with specific azimuth configuration and operation, therefore should not be understood as limiting the present invention.
Referring to Fig.1-2, the multidirectional migration experiment device of a kind of cell, including bottom plate 1, on four madial walls of bottom plate 1
Equipped with the second mounting groove, it is connected with thermal insulation board in the second mounting groove, it can be in the maintenance equipment of longer time by thermal insulation board
Temperature increases the accuracy of experimental data, is angularly equipped with cellular compartments plate 9 on bottom plate 1, bottom plate 1 passes through 9 quilt of cellular compartments plate
It is divided into four test blocks 5, being equipped with cell at the center of bottom plate 1 places blind hole 4, and one end of cellular compartments plate 9 is connected to cell and puts
On the side wall for setting blind hole 4, the other end of cellular compartments plate 9 is connected on the madial wall of bottom plate 1, and four are angularly equipped on bottom plate 1
A cell migration groove 3, cell place blind hole 4 and are equipped with the through-hole to match with cell migration groove 3, cell migration groove 3
One end the side wall that cell places blind hole 4 is connected to by through-hole, the other end of cell migration groove 3 is connected with cell migration blind hole
2, cell migration groove 3 and cell migration blind hole 2 are respectively positioned in test block 5, and movable block is arranged on two lateral walls of bottom plate 1
6, movable block 6 and bottom plate 1 are integrally formed, manufacture easy to produce, and the both sides of bottom plate 1 are also arranged with mounting plate 7, mounting plate 7
It is inside equipped with the first mounting groove 13, one end of mounting plate 7 is interspersed with rotating bar 8, and one end of rotating bar 8 is equipped with rotating handles, rotation
Rubber pad is wrapped on handle, rubber pad is equipped with anti-skid chequer, is rotated convenient for rotating handles by anti-skid chequer, avoids skidding, turn
The other end of lever 8 passes through the side wall of mounting plate 7 and is arranged with worm gear 10, and the side engagement of worm gear 10 is connected with worm screw 15, institute
The top activity for stating worm screw 15 is inserted in the inner top of mounting plate 7, and baffle 11 is connected on the first mounting groove 13, is set on baffle 11
There are loose slot, one end of movable block 6 to pass through loose slot and be equipped with carriage 14, carriage 14 includes groove, and groove is located at
One end of movable block 6 is fixedly connected with fixed link in groove, pulley is rotatably connected in fixed link, and work can be allowed by pulley
Motion block 6 more smoothly moves on the side wall of the first mounting groove 13, and Caton phenomenon, movable block 6 is avoided to pass through carriage 14
It is connected on the side wall of the first mounting groove 13, reserved cavity 16 is equipped between movable block 6 and worm screw 15, reserved cavity 16 can be kept away
Exempt from the collision of bottom plate 1, the side of movable block 6 is connected with telescopic rod 12, and the other end of telescopic rod 12 is connected to the first mounting groove 13
Side wall on, be arranged with spring on the telescopic rod 12.
In the utility model, when user uses the device, cell liquid is placed on cell and is placed in blind hole 4, is then maintained
Migrate temperature so that cell is moved to cell migration blind hole 2 from cell migration groove 3 at leisure, is moved by experimental rig
To during microscopical, when experimental rig is put on the ground so that movable block 6 moves down so that telescopic rod 12
It moving down, the effect to play buffering avoids bottom plate 1 from generating vibration, then rotates rotating bar 8 so that worm gear 10 rotates,
It drives worm screw 15 to rotate, at leisure pushes bottom plate 1, be moved to suitable observation position.
The preferable specific implementation mode of the above, only the utility model, but the scope of protection of the utility model is not
Be confined to this, any one skilled in the art within the technical scope disclosed by the utility model, according to this practicality
Novel technical solution and its utility model design are subject to equivalent substitution or change, should all cover the protection model in the utility model
Within enclosing.
Claims (5)
1. a kind of multidirectional migration experiment device of cell, including bottom plate（1）, which is characterized in that the bottom plate（1）On angularly set
There is cellular compartments plate（9）, the bottom plate（1）Pass through cellular compartments plate（9）It is divided into four test blocks（5）, the bottom plate（1）'s
It is equipped with cell at center and places blind hole（4）, the cellular compartments plate（9）One end be connected to cell place blind hole（4）Side wall
On, the cellular compartments plate（9）The other end be connected to bottom plate（1）Madial wall on, the bottom plate（1）On angularly be equipped with four
A cell migration groove（3）, the cell placement blind hole（4）It is equipped with and cell migration groove（3）The through-hole to match, it is described
Cell migration groove（3）One end pass through through-hole be connected to cell place blind hole（4）Side wall, the cell migration groove（3）'s
The other end is connected with cell migration blind hole（2）, the cell migration groove（3）With cell migration blind hole（2）It is respectively positioned on test block
（5）It is interior, the bottom plate（1）Two lateral walls on be arranged with movable block（6）, the bottom plate（1）Both sides be also arranged with peace
Loading board（7）, the mounting plate（7）Inside it is equipped with the first mounting groove（13）, the mounting plate（7）One end be interspersed with rotating bar（8）,
The rotating bar（8）One end be equipped with rotating handles, the rotating bar（8）The other end pass through mounting plate（7）Side wall and set
Equipped with worm gear（10）, the worm gear（10）Side engagement be connected with worm screw（15）, the worm screw（15）Top activity plug
In mounting plate（7）Inner top, first mounting groove（13）On be connected with baffle（11）, the baffle（11）It is equipped with activity
Slot, the movable block（6）One end pass through loose slot and be equipped with carriage（14）, the movable block（6）Pass through carriage
（14）It is connected to the first mounting groove（13）Side wall on, the movable block（6）And worm screw（15）Between be equipped with reserved cavity（16）,
The movable block（6）Side be connected with telescopic rod（12）, the telescopic rod（12）The other end be connected to the first mounting groove
（13）Side wall on, the telescopic rod（12）On be arranged with spring.
2. the multidirectional migration experiment device of a kind of cell according to claim 1, which is characterized in that the bottom plate（1）'s
It is equipped with the second mounting groove on four madial walls, thermal insulation board is connected in second mounting groove.
3. the multidirectional migration experiment device of a kind of cell according to claim 1, which is characterized in that the carriage
（14）Including groove, the groove is located at movable block（6）One end, be fixedly connected with fixed link, the fixation in the groove
Pulley is rotatably connected on bar.
4. the multidirectional migration experiment device of a kind of cell according to claim 1, which is characterized in that on the rotating handles
It is wrapped with rubber pad, the rubber pad is equipped with anti-skid chequer.
5. the multidirectional migration experiment device of a kind of cell according to claim 1, which is characterized in that the movable block（6）
And bottom plate（1）It is integrally formed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820182926.0U CN207918816U (en) | 2018-02-02 | 2018-02-02 | A kind of multidirectional migration experiment device of cell |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820182926.0U CN207918816U (en) | 2018-02-02 | 2018-02-02 | A kind of multidirectional migration experiment device of cell |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207918816U true CN207918816U (en) | 2018-09-28 |
Family
ID=63603166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820182926.0U Expired - Fee Related CN207918816U (en) | 2018-02-02 | 2018-02-02 | A kind of multidirectional migration experiment device of cell |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207918816U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113046238A (en) * | 2021-03-17 | 2021-06-29 | 河南和泽干细胞基因工程有限公司 | Cell chemotaxis detection device |
-
2018
- 2018-02-02 CN CN201820182926.0U patent/CN207918816U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113046238A (en) * | 2021-03-17 | 2021-06-29 | 河南和泽干细胞基因工程有限公司 | Cell chemotaxis detection device |
| CN113046238B (en) * | 2021-03-17 | 2024-03-26 | 河南和泽干细胞基因工程有限公司 | Cell chemotaxis detection device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN207918816U (en) | A kind of multidirectional migration experiment device of cell | |
| CN208722107U (en) | A kind of information security processor | |
| CN201058457Y (en) | Machine for preparing gypsum model | |
| CN206170093U (en) | Robot body structure | |
| CN204383533U (en) | A kind of alarm type perambulator | |
| CN214954903U (en) | Monitoring and early warning device for KIS cloud server | |
| CN215068146U (en) | Keyboard height adjusting device for computer technology and scientific teaching | |
| CN209333187U (en) | One kind having elevating function game machine metal plate bracket | |
| CN207560047U (en) | One kind is convenient for fixed computer exchange apparatus | |
| CN211896959U (en) | Gibberella oscillation activation vibration shaking table | |
| CN207731210U (en) | A kind of hard disc of computer damping device | |
| CN209459316U (en) | A kind of drying unit of pet bone power mutton stick | |
| CN209358703U (en) | A kind of computer network router apparatus convenient for suspension | |
| CN210698768U (en) | Tumbler music toy capable of developing music talents of children | |
| CN207169053U (en) | A kind of new Deformable toy car | |
| CN209641177U (en) | A kind of economics simulation sand table | |
| CN207539577U (en) | A kind of national literature machine storage device | |
| CN207427001U (en) | A kind of motor starter | |
| CN208174081U (en) | A kind of novel distribution cabinet | |
| CN110033682A (en) | A kind of electrocardiogram teaching simulation display device | |
| CN211853322U (en) | Automatic thermal imaging human body thermometer | |
| CN211568634U (en) | Medicine research and development is with medicine storage device who conveniently gets it filled | |
| CN220582996U (en) | Sugar alcohol drying equipment with compact structure | |
| CN217879438U (en) | Pulse reflection measuring instrument for ultra-long power cable shock wave test | |
| CN221091883U (en) | Contactless storage device is used in production of pet urine pad |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180928 Termination date: 20200202 |