CN207917461U - A kind of monoclonal antibody holder with defencive function - Google Patents

Abstract

The utility model discloses a monoclonal antibody storage box with a protective function, which comprises a storage box, a plurality of U-shaped brackets are arranged in the storage box, and two oppositely arranged half A circular fixed piece, the semicircular fixed piece is fixedly connected with the inner side wall of the U-shaped bracket through the first spring, and the side walls on both sides of the storage box are rotatably connected with a rotating rod, and one end of the rotating rod A rotating handle is fixedly connected, and a support rod is fixedly connected to the inner bottom of the storage box. The end of the rotation rod away from the rotation handle penetrates the support rod and is fixedly sleeved with a first bevel gear. A screw rod is provided inside the storage box. One end of the screw is rotatably connected to the inner bottom of the storage box, and the other end of the screw runs through the bottom of the U-shaped bracket and is rotatably connected to a support plate. The utility model can prevent the activity loss of the antibody caused by the freezing cycle of the antibody, and can avoid the contamination of the antibody caused by the irregular taking of the antibody.

Description

A protective monoclonal antibody storage box

technical field

The utility model relates to the technical field of monoclonal antibody preservation devices, in particular to a monoclonal antibody storage box with a protective function.

Background technique

Antibody molecules are the most widely used protein molecules in the fields of biology and medicine, and are widely used in the fields of disease diagnosis, treatment and scientific research. Proper storage and management of antibodies directly determines the activity and use of antibodies. Most antibody activity can be maintained for months or even years if antibodies are stored and managed properly. Because antibodies are very expensive, even a domestically produced antibody costs hundreds to thousands of yuan. Repeated freeze-thaw cycles can denature the antibody, resulting in reduced antibody binding capacity and thus lower titers. Therefore, how to accurately take the target antibody in the shortest time, and the temperature of other antibodies will drop when taking the antibody, and because the temperature of the antibody needs to be kept constant, the storage ampoule of the antibody needs to be placed deep, which is inconvenient and inconvenient to use by hand. Regular use will cause contamination of the storage box, thereby causing contamination of the antibody in the ampoule.

Utility model content

The purpose of the utility model is to solve the shortcomings in the prior art, and propose a monoclonal antibody storage box with a protective function.

In order to achieve the above object, the utility model adopts the following technical solutions:

A monoclonal antibody storage box with a protective function, comprising a storage box, the storage box is provided with a plurality of U-shaped brackets, and the U-shaped brackets are provided with two oppositely arranged semicircular fixing pieces, The semicircular fixed piece is fixedly connected with the inner side wall of the U-shaped bracket through the first spring, and the side walls on both sides of the storage box are rotatably connected with a rotating rod, and one end of the rotating rod is fixedly connected with a rotating handle The bottom of the storage box is fixedly connected with a support rod, and the end of the rotation rod away from the handle runs through the support rod and is fixedly sleeved with the first bevel gear. The inside of the storage box is provided with a screw rod, and one end of the screw rod It is rotatably connected with the inner bottom of the storage box, the other end of the screw rod runs through the bottom of the U-shaped bracket and is rotatably connected with a support plate, the screw rod is threadedly connected with the U-shaped bracket, and the U-shaped bracket is inserted with a An ampoule, the bottom of the ampoule is in contact with the support plate, a telescopic rod is arranged between the support plate and the U-shaped bracket, and the two ends of the telescopic rod are respectively fixedly connected to the support plate and the U-shaped bracket, The second bevel gear is fixedly sleeved on the screw, and the first bevel gear and the second bevel gear are meshed and connected. The top of the storage box is provided with a plurality of connecting plates, and the two sides of the connecting plate are respectively placed. The inner side wall is fixedly connected to the U-shaped bracket, and the side wall of the storage box is provided with a sliding opening, and a plug-in plate is slidably connected in the sliding opening, and the connecting plate between two adjacent U-shaped brackets is fixed. A connecting block is connected, and the connecting block is provided with a card slot corresponding to the plug-in board. One end of the plug-in board is fixedly connected with a pull rod, and a plurality of second springs are arranged between the pull rod and the storage box. The two sides of the spring are fixedly connected with the storage box and the pull rod respectively, and the other end of the inserting plate passes through the sliding opening and extends into the slot.

Preferably, the rotating rod is rotatably fitted with two support sleeves, and the opposite sides of the two support sleeves respectively abut against the inner wall and the outer wall of the storage box.

Preferably, a third spring is sheathed on the telescopic rod, and both sides of the third spring are respectively fixedly connected to the U-shaped bracket and the support plate.

Preferably, the side of the support plate away from the screw rod is covered with a soft silicone layer.

Preferably, a gasket is provided in the card slot, and one side of the gasket abuts against the insertion plate.

Preferably, a plurality of marking cards respectively corresponding to the ampoules are provided on the connecting plate.

Compared with the prior art, the beneficial effect of the utility model is: by setting a plurality of U-shaped brackets to cooperate with inserting plates, when it is necessary to select antibodies, the corresponding inserting plates can be opened, so that the temperature of other antibodies can not be affected , to maintain the stability of the antibody, through the interaction between the semicircular fixing piece and the first spring, the ampoule can be fixed, and the ampoule is shaken when placed, causing damage to the antibody, and the support is driven by turning the handle The ampoule on the board moves up and down, which is convenient for manual use, and can also prevent bacteria from human hands from entering the storage box and contaminating the antibody in the ampoule during manual use.

Description of drawings

Fig. 1 is the structural representation of the utility model;

Fig. 2 is a top view of the placement box structure of the present invention.

In the figure: 1 placement box, 2 rotating handle, 3 support plate, 4 screw rod, 5 telescopic rod, 6 second bevel gear, 7 first bevel gear, 8 rotating rod, 9 U-shaped bracket, 10 semicircular fixed piece, 11 ampoules, 12 connecting blocks, 13 inserting plates, 14 pull rods, 15 connecting plates, 16 supporting rods, 17 supporting sleeves, 18 marking cards.

Detailed ways

The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. example.

In describing the present utility model, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", The orientation or positional relationship indicated by "outside" is based on the orientation or positional relationship shown in the drawings, which is only for the convenience of describing the utility model and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation , are constructed and operated in a specific orientation and therefore cannot be construed as limiting the invention.

Referring to Figures 1-2, a monoclonal antibody storage box with a protective function includes a storage box 1, a plurality of U-shaped brackets 9 are arranged in the storage box 1, and two oppositely arranged Semicircular fixed piece 10, semicircular fixed piece 10 is fixedly connected with the inner side wall of U-shaped bracket 9 by the first spring, is all rotatably connected with rotating rod 8 on the both side walls of placing case 1, and rotating rod 8 rotates Two support sleeves 17 are socketed, and the opposite sides of the two support sleeves 17 are respectively against the inner wall and the outer wall of the storage box 1 to prevent the rotation rod 8 from shaking. The inner bottom is fixedly connected with a support rod 16, and the end of the rotating rod 8 away from the rotating handle 2 runs through the support rod 16 and is fixedly sleeved with the first bevel gear 7. The telescopic rod 5 is sleeved with a third spring, and the two sides of the third spring They are respectively fixedly connected with the U-shaped bracket 9 and the support plate 3, and the placement box 1 is provided with a screw 4, and one end of the screw 4 is rotationally connected with the inner bottom of the placement box 1, and the other end of the screw rod 4 runs through the U-shaped bracket 9. The bottom is connected with a support plate 3 by rotation, the screw 4 is threadedly connected with the U-shaped bracket 9, and the side of the support plate 3 away from the screw 4 is covered with a silicone soft layer to prevent the support plate 3 from being damaged in contact with the ampoule 11 and protect the The role of the ampoule 11, the U-shaped bracket 9 is inserted with the ampoule 11, the bottom of the ampoule 11 is in contact with the support plate 3, and the telescopic rod 5 is arranged between the support plate 3 and the U-shaped bracket 9, and the telescopic rod The two ends of 5 are fixedly connected with the support plate 3 and the U-shaped bracket 9 respectively, the second bevel gear 6 is fixedly sleeved on the screw 4, the first bevel gear 7 and the second bevel gear 6 are meshed and connected, and the top of the box 1 is placed A plurality of connection plates 15 are provided, and a plurality of marking cards 18 corresponding to the ampoules 11 are provided on the connection plates 15, so as to facilitate finding the required monoclonal antibody ampoules 11, and the inner walls of the box 1 are respectively placed on both sides of the connection plates 15 It is fixedly connected with the U-shaped bracket 9, and the side wall of the storage box 1 is provided with a sliding opening, and a plugboard 13 is slidably connected in the sliding opening, and a connecting plate 15 between two adjacent U-shaped brackets 9 is fixedly connected with a joint block 12, the connecting block 12 is provided with a card slot corresponding to the insert plate 13, and a gasket is provided in the draw slot, and one side of the gasket is offset against the insert plate 13 to prevent bacteria in the air from entering the storage box 1, and the insert plate 13 A pull rod 14 is fixedly connected to one end of the pull rod 14, and a plurality of second springs are arranged between the pull rod 14 and the storage box 1. The two sides of the second spring are respectively fixedly connected with the storage box 1 and the pull rod 14. and extend into the card slot.

In the utility model, after the monoclonal antibody to be preserved is placed in the ampoule 11, the ampoule 11 is placed in the U-shaped bracket 9, and then the device is placed in a constant temperature box for preservation. When the antibody needs to be taken After looking for the corresponding marking card 18, after pulling the pull rod 14, after the inserting plate 13 is disengaged from the draw-in slot on the connecting block 12, turn the turning handle 2, and the turning handle 2 drives the turning rod 8 to rotate, and the turning rod 8 drives the first cone The gear 7 rotates, the first bevel gear 7 drives the second bevel gear 6 to rotate, the second bevel gear 6 drives the screw 4 to rotate, the screw 4 drives the support plate 3 to move up and down, and the adjustment support plate 3 moves upward, so that the ampoule 11 moves upward Movement, after taking the ampoule 11, loosen the pull rod 14, let the inserting plate 13 snap into the slot, and complete the whole process.

The above is only a preferred embodiment of the utility model, but the scope of protection of the utility model is not limited thereto. The equivalent replacement or change of the new technical solution and the concept of the utility model shall be covered by the protection scope of the utility model.

Claims (6)

1. A monoclonal antibody storage box with protective function, comprising a storage box (1), characterized in that a plurality of U-shaped brackets (9) are arranged in the storage box (1), and the U-shaped brackets The frame (9) is provided with two opposite semicircular fixed pieces (10), and the semicircular fixed piece (10) is fixedly connected with the inner side wall of the U-shaped bracket (9) through the first spring, so that Both sides of the storage box (1) are rotatably connected with a rotation rod (8), one end of the rotation rod (8) is fixedly connected with a rotation handle (2), and the inner bottom of the storage box (1) is fixed Connected with a support rod (16), the end of the rotating rod (8) away from the rotating handle (2) runs through the supporting rod (16) and is fixedly sleeved with the first bevel gear (7). The storage box (1) There is a screw (4) inside, one end of the screw (4) is rotatably connected to the inner bottom of the storage box (1), and the other end of the screw (4) runs through the bottom of the U-shaped bracket (9) and is rotatably connected There is a support plate (3), the screw rod (4) is threadedly connected with the U-shaped bracket (9), the U-shaped bracket (9) is inserted with an ampoule (11), and the ampoule (11) The bottom of the support plate (3) is in contact with the support plate (3), and the telescopic rod (5) is arranged between the support plate (3) and the U-shaped bracket (9), and the two ends of the telescopic rod (5) are respectively connected to the support plate (3) is fixedly connected with the U-shaped bracket (9), the screw (4) is fixedly sleeved with the second bevel gear (6), the first bevel gear (7) and the second bevel gear (6) Mesh connection, the top of the placement box (1) is provided with a plurality of connection plates (15), and the two sides of the connection plate (15) are respectively fixedly connected to the inner side wall of the placement box (1) and the U-shaped bracket (9) , the side wall of the placement box (1) is provided with a sliding opening, the sliding plate (13) is slidably connected in the sliding opening, and the connecting plate (15) between two adjacent U-shaped brackets (9) ) is fixedly connected with a connecting block (12), the connecting block (12) is provided with a card slot corresponding to the inserting plate (13), and one end of the inserting plate (13) is fixedly connected with a pull rod (14), the A plurality of second springs are arranged between the pull rod (14) and the storage box (1), and the two sides of the second springs are fixedly connected with the storage box (1) and the pull rod (14) respectively, and the inserting plate (13) The other end passes through the sliding opening and extends into the slot. 2. A monoclonal antibody storage box with protective function according to claim 1, characterized in that, two support sleeves (17) are rotatably connected to the rotation rod (8), and the two support sleeves (17) The opposite side is against the inner wall and the outer wall of the storage box (1) respectively. 3. A protective monoclonal antibody storage box according to claim 1, characterized in that a third spring is sleeved on the telescopic rod (5), and the two sides of the third spring are respectively connected to The U-shaped bracket (9) is fixedly connected with the support plate (3). 4. A protective monoclonal antibody storage box according to claim 1, characterized in that the side of the support plate (3) away from the screw (4) is covered with a soft silicone layer. 5. A protective monoclonal antibody storage box according to claim 1, characterized in that a sealing gasket is provided in the card slot, and one side of the sealing gasket is against the inserting plate (13). 6. A monoclonal antibody storage box with protective function according to claim 1, characterized in that, the connecting plate (15) is provided with a plurality of marking cards (18) corresponding to the ampoules (11) respectively ).