CN207852171U - A kind of flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model - Google Patents
A kind of flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model Download PDFInfo
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- CN207852171U CN207852171U CN201820869487.0U CN201820869487U CN207852171U CN 207852171 U CN207852171 U CN 207852171U CN 201820869487 U CN201820869487 U CN 201820869487U CN 207852171 U CN207852171 U CN 207852171U
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Abstract
The utility model discloses a kind of flexible people's oesophagus, Stomach duodenum and small intestine Integrated Models, it includes oesophagus model, stomach model, duodenum model and small intestine model connected in sequence, it is separately formed multiple through-holes on stomach model, duodenum model and small intestine model, each lead to the hole site is bonded with a secretor respectively, is connected inside secretor model connected to it；The inner surface of oesophagus model and stomach model is respectively formed the texture structure with fold；A large amount of policae circulane is distributed in small intestine mold inner surfaces, is distributed on policae circulane sorbefacient multiple flexible raised；The elasticity of each cast material is consistent with elastically keeping for the oesophagus of true people, Stomach duodenum and small intestine.Flexible people's esophagus, stomach and duodenum mold, and secretor of arranging on Stomach duodenum and small intestine are made using 3-D scanning and the method for 3D printing, there is quasi- real physiological architectural characteristic, in Bionic digestion experiment, improve the accuracy of experiment.
Description
Technical field
The utility model belongs to human digestive organ's simulation technical field, specifically, the utility model is related to a kind of soft
Property people oesophagus, Stomach duodenum and small intestine Integrated Model, in Bionic digestion experiment, improving the accuracy of experiment.
Background technology
External people's Bionic digestion system is the equipment that the digestive system and digestion process of people in vitro is imitated, from engineering
Angle is set out, and external Bionic digestion system can be regarded as the dynamic being made of one or more soft biochemical reactors
System.It is most important wherein to establish complete external bionical people's oesophagus, Stomach duodenum and small intestine model.Due to low cost, just
It is prompt, efficiently, the features such as part or specificity sampling is limited and is easy to without ethics, partial alternative is clinical for external Bionic digestion system
Or zoopery, in the bioavailability of food nutrient composition, medicament slow release, the digestion stability of allergen, probiotics
Many important achievements in research are obtained in the research of digestion survival rate etc., are widely used in food, pharmacy, medical treatment, environment
Etc. multiple research fields.Researchers carry out on the road towards more actualization to optimizing external stomach bionic system
Many beneficial explorations, wherein the morphosis, motion mode and digestive environments of true digestive system are carried out bionical heavy to closing
Want, i.e., by these three bionic patterns, can by complicated and unstable state peptic digest system dismantling at can be detected and
The biochemical reactor system of analysis；These three bionic patterns not only directly determine digestive juice (contain digestive ferment) feeding manner,
Reactant (food materials etc.) and the hybrid mode of digestive juice and the discharge method of reaction product, and affect reactant and entirely disappearing
Change the crushing effect and digestion effect in road.Therefore, it is hair to Bionic conflguration, motion biomimetics and bionical optimize of digestive environments
The key for opening up external bionic system studies a question.And it is to carry out to build accurate true external people's oesophagus, Stomach duodenum and small intestine
The basic link of these work and a most important link.
Bionic digestion experiment is carried out to human organ, it usually needs make some relevant digestive system models, assign simultaneously
It gives digestive system model certain action, makes it have the digestive function of human organ, for carrying out grinding for digestion
Study carefully.The digestive organs model that the research of current carried out digestive system uses and function possessed by true human digestive organ
There are larger difference, cannot imitate the true digestive system of human body completely, therefore when carrying out scientific research, will produce out perhaps
Mostly incredible experiment gathered data, is unfavorable for scientific research.
Utility model content
Therefore, the technical issues of the utility model is solved is to be made with quasi- real physiological architectural characteristic and size
Digestion model, in Bionic digestion experiment, improving the accuracy of experiment.Therefore, the utility model provides a kind of flexible people
Oesophagus, Stomach duodenum and small intestine Integrated Model.
The utility model provides a kind of flexible people's oesophagus, Stomach duodenum and small intestine Integrated Model comprising sequentially
Connection has oesophagus model, stomach model, duodenum model and small intestine model made of elastic material, the stomach model, ten
Multiple through-holes have been separately formed on two duodenum 12 models and small intestine model, each lead to the hole site is bonded with a secretor respectively,
It is connected inside the secretor model connected to it；The inner surface of the oesophagus model and stomach model, which is respectively formed, to be carried
The texture structure of fold；A large amount of policae circulane is distributed in the small intestine mold inner surfaces, is distributed on the policae circulane
It is sorbefacient multiple flexible raised；The elasticity of each cast material and the oesophagus of true people, the elasticity of Stomach duodenum and small intestine
It is consistent.
Preferably, it is multiple it is described it is flexible raised on be additionally provided with microvillus structure.
It is further preferred that the medial surface of the stomach model is equipped with stomach wall, the stomach wall includes the mucous layer of internal layer, outer layer
Placenta percreta and the muscle layer between ectonexine, be located on the mucous layer with the texture structure of fold.
Ratio between the oesophagus of each moulded dimension and true man, Stomach duodenum and small intestine is 1:1.
The secretor is the silicone tube that outer diameter is 2mm, internal diameter 1mm, length are 300~400mm.
Two sides of stomach wall of the stomach model respectively form multiple through-holes, the major papilla position of the duodenum model
It is at least molded a through-hole, the secretor is fixed on one by one in the corresponding through-hole, at the insertion end port of the secretor
Less than or equal to the inner surface of the stomach model and duodenum model.
Two sides of stomach wall of the stomach model respectively form 12 through-holes
The duodenal inside forms annular fold.
Used elastic material is silica gel material, and tensile strength is 4~6kgf/cm2, elongation at break be 300~
800%, tear resistance is 20~30kgf/cm2, linear contraction is≤0.5%.
It is fixedly connected respectively by adhesive-layer between the oesophagus model, stomach model, duodenum model and small intestine model.
Technical solutions of the utility model have the following advantages that：
A. the utility model makes flexible people's esophagus, stomach and duodenum mould using 3-D scanning and the method for 3D printing
Tool, adopts and prepares small intestine mold with machinery method, and flexible people's oesophagus, stomach then is made by overmolded using elastic material flexible
With duodenum model, and secretor of arranging on Stomach duodenum and small intestine, then by flexible people's oesophagus obtained, stomach,
Structure connects in sequence for duodenum and small intestine, produced people's oesophagus flexible, Stomach duodenum and small intestine one
Body model, the model have quasi- real physiological architectural characteristic and size, and with digestive juice secretion function and flexible etc. one
Number of advantages can be used in Bionic digestion experiment, improve the accuracy of experiment.
B. the utility model is equipped with a large amount of fold texture structure on the inner surface of stomach model and oesophagus model, simultaneously also
The stomach wall of stomach model is arranged to three-decker by simulation true man's stomach structure, and policae circulane is arranged in the inner surface of small intestine model,
It is distributed with sorbefacient multiple flexible raised on policae circulane, in a large amount of microvillus structure of flexible raised upper setting, realizes
The real simulation of integrated oesophagus, Stomach duodenum and small intestine.
Description of the drawings
It, below will be right in order to illustrate more clearly of specific embodiment of the present invention or technical solution in the prior art
Specific implementation mode or attached drawing needed to be used in the description of the prior art are briefly described, it should be apparent that, it is described below
In attached drawing be that some embodiments of the utility model are not paying creativeness for those of ordinary skill in the art
Under the premise of labour, other drawings may also be obtained based on these drawings.
Fig. 1 is people's esophageal-gastric-Duodeno- small intestine silica gel model schematic diagram in the utility model；
Fig. 2 is the stomach model internal structure schematic diagram in Fig. 1；
Fig. 3 is the duodenum model structure schematic diagram in Fig. 1；
Fig. 4 is the small intestine model structure schematic diagram in Fig. 1；
Fig. 5 is the small intestine lamps structure schematic diagram of Fig. 4；
Fig. 6 is the inner surface structure partial enlarged view of Fig. 4 Small Intestine models；
Fig. 7 is the structure composition figure of stomach wall in stomach model in Fig. 2.
In figure：
1- oesophagus models；2- stomach models, 21- stomach walls, 211- mucous layers, 212- placenta percretas, 213- muscle layer；3- duodenums
Model, 31- annular folds；4- small intestine models, 41- policae circulanes, 42- is flexible raised, 421- microvillus；5- poly (methyl methacrylate) plates,
51- apertures；6- secretors；.
Specific implementation mode
The technical solution of the utility model is clearly and completely described below in conjunction with attached drawing, it is clear that described
Embodiment is the utility model a part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, originally
The every other embodiment that field those of ordinary skill is obtained without making creative work, belongs to this practicality
Novel protected range.
As shown in Figure 1, the utility model provides a kind of flexible people's oesophagus, Stomach duodenum and small intestine Integrated Model,
It includes oesophagus model 1, stomach model 2, duodenum model 3 and small intestine model 4 connected in sequence, stomach model 2, duodenum mould
Be separately formed multiple through-holes in type 3 and small intestine model 4, each lead to the hole site is bonded with a secretor 6 respectively, secretor 6 with
It is connected inside its model connected；Each equal resilient material of model is made, the oesophagus of the elastic and true people of each cast material,
Stomach duodenum is consistent with elastically keeping for small intestine.Oesophagus model 1, stomach model 2, duodenum model 3 and small intestine model 4 it
Between sequentially pass through adhesive-layer and be fixedly connected, keep the elasticity at link position between model.In the interior table of oesophagus model and stomach model
Face is respectively formed the texture structure with fold；A large amount of policae circulane 41 is distributed in 4 inner surface of small intestine model, in policae circulane
Sorbefacient multiple flexible raised 42 are distributed on 41；Oesophagus, the Stomach duodenum of the elasticity and true people of each cast material
It is consistent with elastically keeping for small intestine.
421 structure of microvillus is preferably additionally provided on multiple flexible raised 42, as shown in fig. 6, more can real simulation it is true
The small intestines structure of people improves experimental precision.
The utility model has produced the integration of people's oesophagus, Stomach duodenum and small intestine flexible by 3D printer
Model, the model have quasi- real physiological architectural characteristic and size, with digestive juice secretion function and flexible etc. a series of
Advantage can be used in Bionic digestion experiment, improve the accuracy of experiment.
Preferably, the ratio between the oesophagus of each moulded dimension and true man, Stomach duodenum and small intestine is 1:1, more favorably
Carry out the digestion experiment of people to the oesophagus, Stomach duodenum and small intestine model that imitate true man in scientific research personnel.
Above-mentioned secretor 6 is the silicone tube that outer diameter is 2mm, internal diameter 1mm, length are 300~400mm.This practicality is new
Type preferably uses the silicone tube of 350mm.
The utility model respectively forms multiple through-holes, preferably 12 through-holes in two sides of stomach wall of stomach model 2, ten
The major papilla position of two duodenum 12 models 3 is at least molded a through-hole, and secretor 6 is fixed on one by one in corresponding through-hole, secretor 6
It is less than or equal to the inner surface of stomach model 2 and duodenum model 3 at insertion end port.Certainly, it is not limited to here in stomach model 2
Each 12 through-holes of molding in both sides, only preferred scheme, can also be respectively set in the both sides of stomach model 2 and be more or less than here
12 through-holes, the technical solution that number of openings here will not protect the utility model are construed as limiting.
More have preferably, annular fold 31 is formed in duodenal inside, as shown in Fig. 3 and Fig. 1, more realistically mould
Intend the duodenum function of true people.
Elastic material used by the utility model is preferably silica gel material, and tensile strength is 4~6kgf/cm2, fracture
Elongation is 300~800%, and tear resistance is 20~30kgf/cm2, linear contraction is≤0.5%.
Specifically, the preparation method of flexible people's oesophagus, Stomach duodenum and small intestine Integrated Model, includes the following steps：
【S1】The oesophagus of people, the inside and outside structure of Stomach duodenum and small intestine are scanned, oesophagus mold, stomach mould is made
Tool, duodenum mold and small intestine mold.
The inside and outside structure for scanning the esophagus, stomach and duodenum of people respectively using spatial digitizer, passes through three-dimensional
Modeling software by the image modeling scanned and preserve at STL formats picture；3-D view is input in 3D printer, according to
Oesophagus mold, stomach mold and the duodenum mold of secondary obtained people.
The preparation of oesophagus mold：
According to the oesophagus physiological data of true people, determine that the mean outside diameter of oesophagus is 20mm, mean inside diameter 15.6mm,
And there are three narrow positions, wherein the first narrow positions is located at the origin or beginning of esophagus, the i.e. junction of pharynx and esophagus；Second narrow
Narrow portion position is below esophagus entrance at 7cm；Third narrow positions is located at esophagogastric intersection.The utility model is according to food
The internal diameter and outer diameter of pipe, produce the mold of the silica gel plate of a plane first, and slot length is 250mm in the mold, wide
Degree is π * oesophaguses overall diameter=62.8mm.Required silica gel amount is 250x62.8x2.2mm3=345.4 milliliters.
Stomach mould preparation method：
The inside and outside structure that true stomach is scanned using spatial digitizer carries out three-dimensionalreconstruction with 3 d modeling software,
And preserve the STL formats identified at 3D printer.It is successively printed with 3D printer.Wherein stomach mold is made of four parts,
Including internal model and external mold, internal model and external mold have two parts assembled respectively, and the medial surface of medial surface, that is, inner membrance of stomach model is set
It includes the mucous layer of internal layer, the placenta percreta of outer layer and the muscle layer between ectonexine to have stomach wall, the stomach wall, carries fold
Texture structure is located on the mucous layer.As shown in Figure 7.
The preparation method of duodenum mold：
The true duodenal inside and outside structure that people is scanned using spatial digitizer is referred to according to the 12 of true people
Intestines data determine that duodenal outer diameter is 70mm, internal diameter 50mm, and have annular fold.
The utility model produces the mould of the silica gel plate of a plane first according to duodenal internal diameter and outer diameter
The interior slot length of tool, the mold is 250mm, and width is π * duodenums overall diameter=219.8mm.Required silica gel amount is
250x219.8x10mm3=549.5 milliliters.
The preparation method of small intestine mold：
As shown in figure 5, according to the small intestine structure size of the obtained true people of spatial digitizer, on poly (methyl methacrylate) plate 5
The smooth aperture 51 with certain intervals, diameter and depth is stamped, small intestine mold is made.
【S2】The uniform smearing release agent on mold, elastic liquid material is cast on mold, through de- after its solidification
Oesophagus model, stomach model, duodenum model and small intestine model is made in mould respectively, and carries out after surface cleaning drying processing,
It is as shown in Figures 2 to 4 respectively.
Prepare silicon rubber liquid：
Calculate the void space reserved between the internal model and external mold of institute's molding jig and bionical people's oesophagus to be manufactured, stomach,
The volume of duodenum and small intestine prepares liquid silica gel, and liquid silica gel and crosslinking agent is mixed and defoamed, and obtains uncrosslinked
Liquid silica gel, the volume for liquid of casting are equal with soft elastic container material volume to be manufactured.Certain the utility model can be with
Using other elastomeric materials.
The mechanical property parameters of wherein silica gel material are:Tensile strength is 40kgf/cm, elongation at break is 300~
600%, tear resistance is 20~30kgf/cm, and linear contraction is≤0.5%.
The wherein preparation method of oesophagus model and duodenum model：According to the oesophagus and ten for the people that 3-D scanning is obtained
The inside/outside diameter size of two duodenum 12 produces the oesophagus mould with plane silica gel plate structure respectively by 3D printer and silica gel material
The length of tool and duodenum mold, mold is respectively oesophagus and duodenal length, and the width of mold is oesophagus and ten
The outer diameter perimeter of two duodenum 12；Two silica gel plates are successively smeared into binder on two sides along its length, after solidification respectively
Oesophagus model is made and duodenum model, the structure chart of duodenum model are as shown in Figure 3.
The preparation method of small intestine model specifically includes：Molding has certain intervals, diameter and depth on poly (methyl methacrylate) plate
Smooth aperture, small intestine mold is made；Elastic liquid material is cast in small intestine by the smearing release agent on organic glass board mold
On mold, its curing and demolding being waited for, and carrying out after surface cleaning drying processing, small intestine preliminary cast is made；By small intestine preliminary cast
Binder is successively smeared on two sides along its length, small intestine model is made after solidification, as shown in Figure 4.
The preparation method of stomach model specifically includes：3D printer is according to the inside and outside size of 3-D scanning income earner's stomach
Print the internal model and external mold of stomach mold；Distinguish smearing release agent to the inner surface of the outer surface of internal model and external mold；In internal model and outside
Mould is formed by cast elastic liquid material in gap, left and right two parts stomach model is made after demoulding after its solidification, through table
It carries out drying processing after the cleaning of face；Two parts stomach model after drying successively is smeared viscous on two sides along its length
Agent is tied, stomach model is made after solidification, as shown in Figure 2.
Silicon rubber is pressed 1:1 mass ratio is mixed, and vacuumizes 10 minutes until all bubbles all disappear.It is clear simultaneously
Each mold is washed, and uniformly coats releasing agent on each mold, is then poured into the desired amount in each mold respectively, wherein oesophagus mould
Tool, duodenum mold and small intestine mold inject in the desired amount, stomach mold (about 650ml) until filling.Silicon rubber will be poured into
Each mold of glue is put into the baking oven less than 40 ° to dry 3 hours and take out, and mold is taken out up to each model.
【S3】It is punched respectively on stomach model, duodenum model and small intestine model, flexible pipe is inserted and fixed in hole
As secretor.Secretor is preferably the silicone tube that outer diameter is 2mm, internal diameter 1mm, length are 300~400mm.
Stomach model obtained and duodenum model and small intestine model are punched with card punch, silicone tube is inserted in the hole simultaneously
It is bonded with glue, silicone tube can protrude a part, wait and have one's hair trimmed close to stomach wall after gluing, while ensure that silicone tube is not blocked up by glue
Plug, and it is no more than the inner surface of stomach model, duodenum model and small intestine model at the port of insertion end.It is small that 3 are placed after gluing
When, then each silicone tube each leads into water-soluble red liquid dyestuff, checks the conducting situation of secretor；Then by stomach
Secretor be integrated on a thicker pipe, every pipe is blocked with the solid electric wire of certain length in advance, prevents glue
It flows into secretor, waits and pulled out again after gluing, and be passed through water-soluble red liquid dyestuff, check whether leakage and blocking.
Each model successively smears silicone adhesive agent, every layer of silicone adhesive agent in the junction of two sides along its length
Hardening time be 2.5~3.5 hours, smear 5~7 layers；The outlet of mold one end is closed, is injected from its other end water-soluble
Red liquid detection of fuel mold whether leakage.
12 holes are made a call to two sides of stomach wall of stomach model are each using the card punch of 5mm, in the big breast of duodenum model
It is at least respectively made a hole on head position and small intestine model, secretor is fixed on one by one in corresponding hole, at the port of insertion end
It is connected no more than the inner surface of stomach model and duodenum model, and with the inside of the stomach model and duodenum model.
【S4】The oesophagus model of bionical people, stomach model, duodenum model and small intestine model are pressed into structure using adhesive
Sequence is got up using silicone adhesive to get Integrated Model, while checking whether leakage.
Obviously, the above embodiments are merely examples for clarifying the description, and does not limit the embodiments.It is right
For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of variation or
It changes.There is no necessity and possibility to exhaust all the enbodiments.And it is extended from this it is obvious variation or
Among the protection domain that variation is created still in the utility model.
Claims (10)
1. a kind of flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model comprising connected in sequence that there is elastic material
Manufactured oesophagus model, stomach model, duodenum model and small intestine model, which is characterized in that the stomach model, duodenum mould
Multiple through-holes are separately formed on type and small intestine model, each lead to the hole site is bonded with a secretor, the secretion respectively
It manages and is connected inside model connected to it；The inner surface of the oesophagus model and stomach model is respectively formed the line with fold
Manage structure；A large amount of policae circulane is distributed in the small intestine mold inner surfaces, and promotion is distributed on the policae circulane and absorbs
It is multiple flexible raised；The elasticity of each cast material elastically keeps one with the oesophagus of true people, Stomach duodenum and small intestine
It causes.
2. flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model according to claim 1, which is characterized in that more
It is a it is described it is flexible raised on be additionally provided with microvillus structure.
3. flexibility people oesophagus according to claim 1 or 2, Stomach duodenum and small intestine Integrated Model, feature exist
It is equipped with stomach wall in the medial surface of, the stomach model, the stomach wall includes the mucous layer of internal layer, the placenta percreta of outer layer and positioned inside and outside
Muscle layer between layer, the texture structure with fold are located on the mucous layer.
4. flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model according to claim 3, which is characterized in that each
Ratio between the oesophagus of moulded dimension and true man, Stomach duodenum and small intestine is 1:1.
5. flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model according to claim 4, which is characterized in that institute
It is the silicone tube that outer diameter is 2mm, internal diameter 1mm, length are 300~400mm to state secretor.
6. flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model according to claim 4, which is characterized in that institute
Two sides of stomach wall for stating stomach model respectively form multiple through-holes, and the major papilla position of the duodenum model is at least molded one
Through-hole, the secretor are fixed on one by one in the corresponding through-hole, and institute is less than or equal at the insertion end port of the secretor
The inner surface of the stomach model and duodenum model stated.
7. flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model according to claim 6, which is characterized in that institute
Two sides of stomach wall for stating stomach model respectively form 12 through-holes.
8. flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model according to claim 7, which is characterized in that institute
It states duodenal inside and forms annular fold.
9. flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model according to claim 8, which is characterized in that institute
For the elastic material used for silica gel material, tensile strength is 4~6kgf/cm2, elongation at break is 300~800%, tear-resistant
Intensity is 20~30kgf/cm2, linear contraction is≤0.5%.
10. flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model according to claim 9, which is characterized in that
It is fixedly connected respectively by adhesive-layer between the oesophagus model, stomach model, duodenum model and small intestine model.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109166439A (en) * | 2018-10-30 | 2019-01-08 | 河南科技大学 | A kind of production method of the stomach section silica gel model of sheep |
| CN109333883A (en) * | 2018-09-29 | 2019-02-15 | 江南大学 | A kind of bionical ileum and preparation method thereof |
| WO2019034008A1 (en) * | 2017-08-14 | 2019-02-21 | 中粮营养健康研究院有限公司 | Method for fabricating integrated model of flexible human esophagus, stomach, duodenum, and small intestine, and dynamic in vitro biomimetic digestive system thereof |
| CN109637323A (en) * | 2019-02-20 | 2019-04-16 | 晓东宜健（苏州）仪器设备有限公司 | A kind of bionical human body duodenum, small intestine and large intestine digestive system |
| CN109938876A (en) * | 2019-04-02 | 2019-06-28 | 青岛市城阳区人民医院 | A kind of method of 3D printing production stomach and intestine nursing film |
| CN110895896A (en) * | 2019-11-27 | 2020-03-20 | 宁波创导三维医疗科技有限公司 | Electric knife cuttable bionic gastrointestinal tract operation model and manufacturing method thereof |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019034008A1 (en) * | 2017-08-14 | 2019-02-21 | 中粮营养健康研究院有限公司 | Method for fabricating integrated model of flexible human esophagus, stomach, duodenum, and small intestine, and dynamic in vitro biomimetic digestive system thereof |
| CN109333883A (en) * | 2018-09-29 | 2019-02-15 | 江南大学 | A kind of bionical ileum and preparation method thereof |
| CN109166439A (en) * | 2018-10-30 | 2019-01-08 | 河南科技大学 | A kind of production method of the stomach section silica gel model of sheep |
| CN109166439B (en) * | 2018-10-30 | 2020-11-13 | 河南科技大学 | Method for manufacturing sheep gastric section silica gel model |
| CN109637323A (en) * | 2019-02-20 | 2019-04-16 | 晓东宜健（苏州）仪器设备有限公司 | A kind of bionical human body duodenum, small intestine and large intestine digestive system |
| CN109637323B (en) * | 2019-02-20 | 2024-01-12 | 晓东宜健（苏州）仪器设备有限公司 | Bionic human duodenum, small intestine and large intestine digestive system |
| CN109938876A (en) * | 2019-04-02 | 2019-06-28 | 青岛市城阳区人民医院 | A kind of method of 3D printing production stomach and intestine nursing film |
| CN110895896A (en) * | 2019-11-27 | 2020-03-20 | 宁波创导三维医疗科技有限公司 | Electric knife cuttable bionic gastrointestinal tract operation model and manufacturing method thereof |
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