CN207845529U - A kind of preparation facilities obtaining high-purity esomeprazole sodium - Google Patents
A kind of preparation facilities obtaining high-purity esomeprazole sodium Download PDFInfo
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- CN207845529U CN207845529U CN201721899395.9U CN201721899395U CN207845529U CN 207845529 U CN207845529 U CN 207845529U CN 201721899395 U CN201721899395 U CN 201721899395U CN 207845529 U CN207845529 U CN 207845529U
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- agitating shaft
- pond
- preparation facilities
- obtaining high
- esomeprazole sodium
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Abstract
The application belongs to field of chemical equipment, specially a kind of preparation facilities obtaining high-purity esomeprazole sodium.Including passing through the sequentially connected reaction kettle of pipeline, heat exchanger, filter device, filtrate receiver, the first rectifier unit, alkali pond, sour pond, neutralization pond, aerobic tank, anaerobic pond, aeration and biological pond and sterilization pool, the filter device is connected by pipeline with strainer tub, the strainer tub is connected by pipeline with organic dissolution pond, the organic dissolution pond is connected with the second filter device, and second filter device is connected by pipeline with the second rectifier unit and filter residue collecting case respectively.
Description
Technical field
The application belongs to field of chemical equipment, specially a kind of preparation facilities obtaining high-purity esomeprazole sodium.
Background technology
Esomeprazole sodium is a kind of important drugs for treating disease of stomach, and existing production is used first to prepare to detach afterwards and be carried
Pure mode is unable to continuous production, and generates a large amount of organic liquid wastes in process of production, pollutes environment.
Invention content
In order to solve the above-mentioned technical problem, this application provides a kind of preparation dresses obtaining high-purity esomeprazole sodium
It sets, the application is realized by following proposal：
It is a kind of obtain high-purity esomeprazole sodium preparation facilities, including by the sequentially connected reaction kettle of pipeline, change
Hot device, filter device, filtrate receiver, the first rectifier unit, alkali pond, sour pond, neutralization pond, aerobic tank, anaerobic pond, aeration and biological pond and
Sterilization pool, the filter device are connected by pipeline with strainer tub, and the strainer tub is connected by pipeline with organic dissolution pond
It connects, the organic dissolution pond is connected with the second filter device, and second filter device passes through pipeline and the second rectifying respectively
Device is connected with filter residue collecting case.
Preferably, the reaction kettle includes autoclave body, and the outside of the autoclave body is equipped with thermal-insulation coat, and the is equipped in the autoclave body
One agitating shaft is uniformly provided with stirring blade on first agitating shaft.
Preferably, it is equipped with the second horizontal agitating shaft and horizontal third agitating shaft in the middle part of the autoclave body, described second stirs
The one end for mixing axis is connected with kettle wall, and the other end of second agitating shaft is equipped with annular blender, the third agitating shaft
One end is connected with kettle wall, and the other end of the third agitating shaft is equipped with annular blender.
Preferably, it is hollow structure inside the annular blender, is uniformly provided on the annular blender side wall several
Through-hole.
Preferably, the autoclave body be equipped with the matched first motor of the first agitating shaft, matched with the second agitating shaft
The second motor, with the matched third motor of third agitating shaft.
Preferably, the stirring blade is equipped with tapered protrusion.
Preferably, jacket type electric heater is equipped in the chuck between thermal-insulation coat and autoclave body.
The application is simple in structure easy to use, and the reactant of rectifying recycling is also reusable, has saved cost, waste liquid into
It is discharged again after row processing, it is free from environmental pollution.
Description of the drawings
Fig. 1 is the embodiment of the present application structural schematic diagram；
Fig. 2 is the embodiment of the present application reaction kettle structural schematic diagram；
Wherein, 1, reaction kettle, 2, heat exchanger, 3, filter device, 4, filtrate receiver, the 5, first rectifier unit, 6, alkali pond, 7, acid
Pond, 8, neutralization pond, 9, aerobic tank, 10, anaerobic pond, 11, aeration and biological pond, 12, sterilization pool, 13, strainer tub, 14, organic dissolution
Pond, the 15, second filter device, the 16, second rectifier unit, 17, filter residue collection tank, 18, thermal-insulation coat, the 19, first agitating shaft,
20, stirring blade, the 21, second agitating shaft, 22, third agitating shaft, 23, annular blender, 24, first motor, the 25, second electricity
Machine, 26, third motor.
Specific implementation mode
Embodiment 1
It is a kind of obtain high-purity esomeprazole sodium preparation facilities, including by the sequentially connected reaction kettle 1 of pipeline, change
Hot device 2, filtrate receiver 4, the first rectifier unit 5, alkali pond 6, sour pond 7, neutralization pond 8, aerobic tank 9, anaerobic pond 10, exposes at filter device 3
Gas biological tank 11 and sterilization pool 12, the filter device 3 are connected by pipeline with strainer tub 13, and the strainer tub 13 passes through pipe
Road is connected with organic dissolution pond 14, and the organic dissolution pond 14 is connected with the second filter device 15, the second filtering dress
15 are set respectively to be connected with the second rectifier unit 16 and filter residue collecting case 17 by pipeline.
Embodiment 2
On the basis of embodiment 1, the reaction kettle includes autoclave body, and the outside of the autoclave body is equipped with thermal-insulation coat 18, institute
It states and is equipped with the first agitating shaft 19 in autoclave body, stirring blade 20 is uniformly provided on first agitating shaft 19.
Embodiment 3
The second horizontal agitating shaft 21 and the stirring of horizontal third are equipped on the basis of embodiment 2, in the middle part of the autoclave body
One end of axis 22, second agitating shaft 21 is connected with kettle wall, and the other end of second agitating shaft 21 is equipped with annular and stirs
One end of device 23, the third agitating shaft 22 is connected with kettle wall, and the other end of the third agitating shaft 22 is equipped with annular and stirs
Device 23, the first agitating shaft and the second agitating shaft are oppositely arranged.
Embodiment 4
On the basis of embodiment 3,23 inside of annular blender is hollow structure, on the annular blender side wall
It is uniformly provided with several through-holes.
Embodiment 5
On the basis of embodiment 4, the autoclave body be equipped with the matched first motor 24 of the first agitating shaft, with second
Matched second motor 25 of agitating shaft, with the matched third motor of third agitating shaft 25.
Embodiment 6
On the basis of embodiment 5, the stirring blade is equipped with tapered protrusion.
Embodiment 7
On the basis of embodiment 6, jacket type electric heater is equipped in the chuck between thermal-insulation coat and autoclave body.
Claims (7)
1. a kind of preparation facilities obtaining high-purity esomeprazole sodium, which is characterized in that including sequentially connected by pipeline
Reaction kettle, heat exchanger, filter device, filtrate receiver, the first rectifier unit, alkali pond, sour pond, neutralization pond, aerobic tank, anaerobic pond, exposure
Gas biological tank and sterilization pool, the filter device are connected by pipeline with strainer tub, the strainer tub by pipeline with it is organic
Dissolving tank is connected, and the organic dissolution pond is connected with the second filter device, and second filter device passes through pipeline respectively
It is connected with the second rectifier unit and filter residue collecting case.
2. a kind of preparation facilities obtaining high-purity esomeprazole sodium as described in claim 1, which is characterized in that described anti-
It includes autoclave body to answer kettle, and the outside of the autoclave body is equipped with thermal-insulation coat, and the first agitating shaft, first stirring are equipped in the autoclave body
Stirring blade is uniformly provided on axis.
3. a kind of preparation facilities obtaining high-purity esomeprazole sodium as claimed in claim 2, which is characterized in that the kettle
The second horizontal agitating shaft and horizontal third agitating shaft are equipped in the middle part of body, one end of second agitating shaft is connected with kettle wall
It connects, the other end of second agitating shaft is equipped with annular blender, and one end of the third agitating shaft is connected with kettle wall, described
The other end of third agitating shaft is equipped with annular blender.
4. a kind of preparation facilities obtaining high-purity esomeprazole sodium as claimed in claim 3, which is characterized in that the ring
It is hollow structure inside shape blender, several through-holes is uniformly provided on the annular blender side wall.
5. a kind of preparation facilities obtaining high-purity esomeprazole sodium as claimed in claim 2, which is characterized in that the kettle
Body is equipped with to be stirred with matched second motor of the second agitating shaft with third with the matched first motor of the first agitating shaft
The matched third motor of axis.
6. a kind of preparation facilities obtaining high-purity esomeprazole sodium as claimed in claim 2, which is characterized in that described to stir
It mixes blade and is equipped with tapered protrusion.
7. a kind of preparation facilities obtaining high-purity esomeprazole sodium as described in claim 1, which is characterized in that heat preservation is outer
Jacket type electric heater is equipped in chuck between set and autoclave body.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721899395.9U CN207845529U (en) | 2017-12-29 | 2017-12-29 | A kind of preparation facilities obtaining high-purity esomeprazole sodium |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721899395.9U CN207845529U (en) | 2017-12-29 | 2017-12-29 | A kind of preparation facilities obtaining high-purity esomeprazole sodium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207845529U true CN207845529U (en) | 2018-09-11 |
Family
ID=63419858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721899395.9U Active CN207845529U (en) | 2017-12-29 | 2017-12-29 | A kind of preparation facilities obtaining high-purity esomeprazole sodium |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207845529U (en) |
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2017
- 2017-12-29 CN CN201721899395.9U patent/CN207845529U/en active Active
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