CN207785310U - A kind of fixing device for experimental mouse intrathecal injection - Google Patents

A kind of fixing device for experimental mouse intrathecal injection Download PDF

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Publication number
CN207785310U
CN207785310U CN201720493396.7U CN201720493396U CN207785310U CN 207785310 U CN207785310 U CN 207785310U CN 201720493396 U CN201720493396 U CN 201720493396U CN 207785310 U CN207785310 U CN 207785310U
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CN
China
Prior art keywords
fixed column
spring
arc panel
experimental mouse
sliding
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Expired - Fee Related
Application number
CN201720493396.7U
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Chinese (zh)
Inventor
肖智
秦颖
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Zunyi Medical University
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Zunyi Medical University
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Priority to CN201720493396.7U priority Critical patent/CN207785310U/en
Application granted granted Critical
Publication of CN207785310U publication Critical patent/CN207785310U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

This application discloses a kind of fixing devices for experimental mouse intrathecal injection of laboratory equipment technical field, including arc panel, one end of arc panel is equipped with fixed mechanism and the first sliding groove, fixed mechanism includes preceding fixed column and rear fixed column, the orientation of preceding fixed column and rear fixed column is identical as the width direction of arc panel, and rear fixed column is fixed on arc panel;Preceding fixed column is slidably connected in the first sliding groove, the first spring is equipped in the first sliding groove, one end of first spring is connected with preceding fixed column, the side wall far from rear fixed column side connects in the other end and the first sliding groove of first spring, preceding fixed column and rear fixed column are equipped with second sliding slot along its axis direction, sliding block and second spring are equipped in second sliding slot, one end of second spring is connected with sliding block, the other end of second spring is connected with the upper inner wall of second sliding slot or lower inner wall, and telescopic rod is also associated between two sliding blocks.It is convenient for carrying out intrathecal injection to experimental mouse using the fixing device in this programme.

Description

A kind of fixing device for experimental mouse intrathecal injection
Technical field
The utility model is related to laboratory equipment technical fields, and in particular to a kind of fixation for experimental mouse intrathecal injection Device.
Background technology
Animal pain models are widely used in the model for making various clinically relevant diseases at present, are making model When, intrathecal injection has become the major way of researcher's administration.Intrathecal injection is under a kind of common arachnoid of spinal cord Chamber administering mode, intrathecal by the spinal cord that the syringe needle of syringe is inserted into animal, medicine directly acts on the nervous centralis of animal System, its advantage is that rapid-action and effect is good.
Pain model presently mainly is made with experimental mouse, intrathecal injection is carried out after experimental mouse anesthesia.For using When carrying out the experimental mouse of intrathecal injection after inhalation anesthetic, at least two people are generally required on operation console to operate, one People fixes the head of experimental mouse come spinal fixation with hand, regains consciousness to prevent the experimental mouse under light anaesthesia, and the physiological property of backbone There is certain radian, in order to find the gap between vertebra, usually also needs to another people and the back of experimental mouse is arched upward To suitable radian, injected after touching gap.But since experimental mouse volume is too small, coordinates between operator and do not lead closely Cause experimental mouse head to fix bad, vertebra gap is not easy to be touched, and leads to not inject drug, extend injection drug when Between.
Utility model content
The utility model is intended to provide a kind of fixing device for experimental mouse intrathecal injection, real in the prior art to solve It tests mouse head and fixes bad the problem of leading to not inject drug.
In order to solve the above problem, the utility model provides following base case:A kind of consolidating for experimental mouse intrathecal injection Determine device, including arc panel, one end of arc panel is equipped with fixed mechanism and the first sliding groove, and fixed mechanism includes preceding fixed column with after Fixed column, the orientation of preceding fixed column and rear fixed column is identical as the width direction of arc panel, and rear fixed column is fixed on arc On plate;Preceding fixed column is slidably connected in the first sliding groove, is equipped with the first spring in the first sliding groove, one end of the first spring and preceding solid Fixed column connects, and the side wall far from rear fixed column side connects in the other end and the first sliding groove of the first spring, and preceding fixed column is with after Fixed column is equipped with second sliding slot along its axis direction, is equipped with sliding block and second spring in second sliding slot, and the one of second spring End is connected with sliding block, and the other end of second spring is connected with the upper inner wall of second sliding slot or lower inner wall, is also connected between two sliding blocks It is connected to telescopic rod.
The operation principle of the utility model:When in use, the both ends of arc panel are fixed on operation console, arc panel Inner concave is towards operation console, and postanesthetic experimental mouse lies prone on arc panel and makes its back upward, and arc panel makes the back of the body of experimental mouse Portion bends to certain radian;Fixed column is slided in the first sliding groove before pulling, and telescopic rod starts to extend, preceding fixed column compression the One spring, while telescopic rod is pulled up, sliding block slides in second sliding slot and stretches second spring, telescopic rod and preceding fixed column After being adjusted to suitable position, the head of experimental mouse is positioned between preceding fixed column and rear fixed column, decontrols telescopic rod with before Fixed column, after telescopic rod and preceding fixed column touch the head of experimental mouse, the head of experimental mouse stops the first spring and second Spring returns to nature, and elastic force makes telescopic rod and preceding fixed column give the head of experimental mouse certain pressure, makes the head of experimental mouse Portion is fixed on arc panel.
The beneficial effects of the utility model:1, arc panel can make the flexes of experimental mouse at certain radian, compare In the prior art, need manually the back hogback by experimental mouse it is time saving and energy saving to certain radian.2, preceding fixed column is in the first sliding groove Interior sliding, telescopic rod can extend or shorten, and can meet the fixation on different size experimental mouse head.3, the first spring is utilized The head of experimental mouse is fixed with the elastic force of second spring, preceding fixed column, rear fixed column, telescopic rod and arc panel are to experiment Mouse carries out the fixation of four direction, and good fixing effect is beneficial to touch vertebra gap, is conducive to carry out intrathecal injection to experimental mouse.
The curvature of scheme two, the optimization to base case, the arc panel is 0.28.In order to make arc panel crooked experiment mouse Back to suitable radian, design this prioritization scheme, when the curvature of arc panel is 0.28, the crooked radian of arc panel is big, real The gap tested between mouse vertebra is big, is conducive to find gap, convenient for carrying out intrathecal injection to experimental mouse.
The inner concave of scheme three, the optimization to scheme two, the arc panel is equipped with multiple annulus.Experimental mouse is during injection It can be tampered after awake, cause intrathecal injection to fail, therefore design this prioritization scheme, by being inserted in rope in annulus by experimental mouse Body and tail be fixed.
The surface of scheme four, the optimization to scheme three, the arc panel is equipped with skid resistant course.Experimental mouse is lain prone on arc panel When, arcuate structure can be such that experimental mouse is slid from arc panel, and the frictional force between skid resistant course and experimental mouse body is big, prevent from testing Mouse slides from arc panel.
Description of the drawings
Fig. 1 is a kind of structural schematic diagram of fixing device for experimental mouse intrathecal injection of the utility model;
Fig. 2 is the partial structural diagram of Fig. 1;
Fig. 3 is the structural schematic diagram of right support column in Fig. 1.
Specific implementation mode
The utility model is described in further detail below by specific implementation mode:
Reference numeral in Figure of description includes:Annulus 1, arc panel 2, rear fixed column 3, second sliding slot 4, preceding fixed column 5, skid resistant course 6, the first sliding groove 7, the first spring 8, telescopic rod 9, second spring 10, sliding block 11.
Embodiment is basic as shown in attached drawing 1, Fig. 2 and Fig. 3:A kind of fixing device for experimental mouse intrathecal injection, including The both ends of arc panel 2, arc panel 2 are fixed on operation console, and towards operation console, arc panel 2 is equipped with anti-the inner concave of arc panel 2 The inner concave of slip layer 6, arc panel 2 is equipped with ten annulus 1, and the curvature that arc panel 2 is bent is 0.28;One end of arc panel 2 is equipped with Fixed mechanism and the first sliding groove 7, fixed mechanism include preceding fixed column 5 and rear fixed column 3, the row of preceding fixed column 5 and rear fixed column 3 Column direction is identical as the width direction of arc panel 2, and rear fixed column 3 is fixed on arc panel 2;Preceding fixed column 5 is slidably connected at In one sliding slot 7, the first spring 8 is equipped in the first sliding groove 7, one end of the first spring 8 and preceding fixed column 5 connect, the first spring 8 The other end is connect with the side wall far from 3 side of rear fixed column in the first sliding groove 7, i.e. the other end of the first spring 8 and the first sliding groove 7 Inner wall positioned at outside connects, and preceding fixed column 5 and rear fixed column 3 are equipped with second sliding slot 4, second sliding slot along its axis direction Sliding block 11 and second spring 10 are equipped in 4, one end of second spring 10 and sliding block 11 connect, the other end of second spring 10 and the The upper inner wall of two sliding slots 4 or the connection of lower inner wall, this programme preferably descend inner wall, telescopic rod 9 are also associated between two sliding blocks 11.
When in use, the both ends of arc panel 2 are fixed on operation console, and the inner concave of arc panel 2 is numb towards operation console Experimental mouse after liquor-saturated lies prone on arc panel 2 and makes its back upward, and body and tail of the rope by experimental mouse are inserted in annulus 1 It bar is fixed, arc panel 2 makes the flexes of experimental mouse at certain radian;Fixed column 5 is sliding in the first sliding groove 7 before pulling Dynamic, telescopic rod 9 starts to extend, and preceding fixed column 5 compresses the first spring 8, while pulling up telescopic rod 9, and sliding block 11 is slided second It is slided in slot 4 and stretches second spring 10, after telescopic rod 9 and preceding fixed column 5 are adjusted to suitable position, by the head of experimental mouse It is positioned between preceding fixed column 5 and rear fixed column 3, telescopic rod 9 and preceding fixed column 5 is decontroled, when telescopic rod 9 and preceding fixed column 5 connect Behind the head for contacting experimental mouse, the head of experimental mouse stops that the first spring 8 and second spring 10 return to nature, and elastic force makes to stretch Contracting bar 9 and preceding fixed column 5 give the head of experimental mouse certain pressure, and the head of experimental mouse is made to be fixed on arc panel 2.
Above-described is only the embodiments of the present invention, and the common sense such as well known concrete structure and characteristic are herein in scheme It does not describe excessively.It should be pointed out that for those skilled in the art, in the premise for not departing from the utility model structure Under, several modifications and improvements can also be made, these should also be considered as the scope of protection of the utility model, these are not all interfered with The effect and patent practicability that the utility model is implemented.This application claims protection domain should be with the content of its claim Subject to, the records such as specific implementation mode in specification can be used for explaining the content of claim.

Claims (4)

1. a kind of fixing device for experimental mouse intrathecal injection, it is characterised in that:Including arc panel, one end of arc panel is equipped with Fixed mechanism and the first sliding groove, fixed mechanism include preceding fixed column and rear fixed column, the arrangement side of preceding fixed column and rear fixed column To identical as the width direction of arc panel, rear fixed column is fixed on arc panel;Preceding fixed column is slidably connected in the first sliding groove, The first spring is equipped in the first sliding groove, one end of the first spring is connected with preceding fixed column, and the other end of the first spring and first is slided The side wall far from rear fixed column side connects in slot, and preceding fixed column and rear fixed column are equipped with the second cunning along its axis direction Slot is equipped with sliding block and second spring in second sliding slot, and one end of second spring is connected with sliding block, the other end of second spring and the The upper inner wall of two sliding slots or lower inner wall connect, and telescopic rod is also associated between two sliding blocks.
2. a kind of fixing device for experimental mouse intrathecal injection according to claim 1, it is characterised in that:The arc The curvature of plate is 0.28.
3. a kind of fixing device for experimental mouse intrathecal injection according to claim 2, it is characterised in that:The arc The inner concave of plate is equipped with multiple annulus.
4. a kind of fixing device for experimental mouse intrathecal injection according to claim 3, it is characterised in that:The arc The surface of plate is equipped with skid resistant course.
CN201720493396.7U 2017-05-05 2017-05-05 A kind of fixing device for experimental mouse intrathecal injection Expired - Fee Related CN207785310U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201720493396.7U CN207785310U (en) 2017-05-05 2017-05-05 A kind of fixing device for experimental mouse intrathecal injection

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201720493396.7U CN207785310U (en) 2017-05-05 2017-05-05 A kind of fixing device for experimental mouse intrathecal injection

Publications (1)

Publication Number Publication Date
CN207785310U true CN207785310U (en) 2018-08-31

Family

ID=63274016

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201720493396.7U Expired - Fee Related CN207785310U (en) 2017-05-05 2017-05-05 A kind of fixing device for experimental mouse intrathecal injection

Country Status (1)

Country Link
CN (1) CN207785310U (en)

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GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20180831

Termination date: 20200505

CF01 Termination of patent right due to non-payment of annual fee