CN207734155U - Imaging device and equipment for molecular image operation - Google Patents

Imaging device and equipment for molecular image operation Download PDF

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Publication number
CN207734155U
CN207734155U CN201720272519.4U CN201720272519U CN207734155U CN 207734155 U CN207734155 U CN 207734155U CN 201720272519 U CN201720272519 U CN 201720272519U CN 207734155 U CN207734155 U CN 207734155U
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China
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light splitting
connection seat
splitting piece
hole
imaging device
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CN201720272519.4U
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Chinese (zh)
Inventor
曾旸
邓联军
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Beijing digital precision medical technology Co., Ltd.
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Shenzhen Hopeful Technology Co Ltd
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Abstract

The utility model is related to the imaging device performed the operation for molecular image and equipment;Wherein imaging device, including shell, shell is interior to be equipped with the accommodating chamber for accommodating camera module, light splitting piece, connection seat, filter component and thang-kng component;Thang-kng component by connection seat couple with filter component and positioned at the front end of filter component;Camera module includes the fluorescence camera of the color camera and horizontal direction set on vertical direction.The utility model is electrically connected by color camera, fluorescence camera and host computer, and laser generator is connect with interior pipe progress light path of peeping, and is inside peeped pipe and is peeped pipe coupling head with interior and couple;Light source is detached using light splitting piece, is transmitted to color camera in vertical direction reflection ordinary ray, horizontal direction transmission near infrared light is transmitted to fluorescence camera;Host computer carries out calculating combination for handling the coloured image received from color camera, fluorescence camera and IR fluorescence image, and precise positioning borderline tumor detects small metastatic lesion.

Description

Imaging device and equipment for molecular image operation
Technical field
The utility model is related to imaging fields, the more particularly, to imaging device and equipment of molecular image operation.
Background technology
With the arriving of the completion and genome times afterwards comprehensively of human genome sequencing, the early stage Precise Diagnosis of disease becomes The Major Strategic Demand of country.Caused by the traditional image technology of molecular image technological break-through is only capable of displaying and is changed by cellular elements Anatomical structure variation limitation, changing traditional ex vivo approach cannot be in body continuous observation drug mechanism and therapeutic effect Limitation, erected between molecular biology and clinical medicine be connected with each other bridge.Molecular image equipment can be in cell Organism physiology, the real-time of pathology, dynamic, imaging in vivo are realized on molecular level, and there is "dead", high sensitivity, measurement The advantages that quick, represents the new direction of Medical Imaging Technology development.It, on the one hand can be swollen to heeling-in using molecular image technology Tumor is accurately positioned, and realizes the thorough excision of tumour, mitigates the unnecessary damage of normal tissue organ;On the other hand, may be used Greatly to shorten the development, screening, pre- clinical research time of drug.However, existing molecular image equipment is relative complex, and grasp It bothers, needs to be further increased in actual use performance and design aspect.
Utility model content
The purpose of the utility model is to overcome the defect of the prior art, the imaging device performed the operation for molecular image is provided And equipment.
To achieve the above object, the utility model uses following technical scheme:
For the imaging device of molecular image operation, including shell, it is equipped in the shell and accommodates camera module, light splitting The accommodating chamber of piece, connection seat, filter component and thang-kng component;The thang-kng component is joined by the connection seat and filter component Connect and positioned at filter component front end, the connection seat be equipped with hollow cavity, and communicated with hollow cavity front through hole, rear through-hole and on Through-hole;The light splitting piece is fixed on the left or right side of connection seat;The camera module includes the colored phase set on vertical direction The fluorescence camera of machine and horizontal direction.
Its further technical solution is:The imaging device further includes adjusting machine for fixing the light splitting piece of light splitting piece Structure, the light splitting piece regulating mechanism include light splitting piece mounting disc, adjusting bracket and light splitting piece angle adjustment plate;The light splitting piece peace Sabot couples with connection seat, and the light splitting piece is fixed on the outside of light splitting piece mounting disc, the light splitting piece mounting disc and adjusting bracket It is clamped and on the inside of adjusting bracket, the adjusting bracket is fixedly connected with light splitting piece angle adjustment plate and is located at light splitting piece angle On the inside of adjustable plate.
Its further technical solution is:The shell includes left housing and right shell;The connection seat is fixed on right shell;The right side Shell is equipped with the first mounting bracket for fixing color camera and the second mounting bracket for fixing fluorescence camera;The left housing Equipped with the connection part for fixing light splitting piece angle adjustment plate;Articulated connection is equipped with the adjusting for adjusting light splitting piece angle Hole.
Its further technical solution is:The filter component include the first convex lens, the second convex lens, the first filter piece and Second filter piece;First convex lens is set to the front through hole of connection seat and couples with thang-kng component;The first filter piece is set In connection seat upper through-hole and couple with the first mounting bracket;After second convex lens, the second filter piece are set to connection seat Through-hole and couple with the second mounting bracket.
Its further technical solution is:First mounting bracket couples with connection seat and positioned at the upper end of connection seat, institute It states the first mounting bracket and is equipped with first through hole corresponding with upper through-hole.
Its further technical solution is:Second mounting bracket couples with connection seat and positioned at the rear end of connection seat, institute It states the second mounting bracket and is equipped with the second through-hole corresponding with rear through-hole;Second convex lens is located at the second filter piece front end; Second convex lens is identical as the second filter optic diameter.
Its further technical solution is:The thang-kng component includes lantern ring and the thang-kng part coupled with lantern ring, the thang-kng Part is located at the rear end of lantern ring;The thang-kng part is equipped with light hole corresponding with front through hole, and the thang-kng part couples with connection seat.
Its further technical solution is:The imaging device peeps pipe coupling head in further including, it is described in peep pipe coupling head Couple with lantern ring and is located at lantern ring front end.
For the imaging device of molecular image operation, including above-mentioned imaging device and the electricity with the electric connection of camera module Brain server, laser generator and interior peep pipe;The laser generator is connect with interior pipe progress light path of peeping;Pipe is peeped in described to peep with interior Pipe coupling head couples.
The advantageous effect of the utility model compared with prior art is:By camera module in housing accommodating chamber, Light splitting piece, connection seat, filter component and thang-kng component, thang-kng component are coupled with filter component by connection seat and are located at filter group The front end of part, light splitting piece are fixed on the left side of connection seat;Color camera, fluorescence camera and host computer are electrically connected, laser hair Raw device is connect with interior pipe progress light path of peeping, and is inside peeped pipe and is peeped pipe coupling head with interior and couple;Light source is detached using light splitting piece, in Vertical Square It is transmitted to color camera to reflection ordinary ray, horizontal direction transmission near infrared light is transmitted to fluorescence camera;Host computer is for handling The coloured image and IR fluorescence image received from color camera, fluorescence camera, and carry out calculating combination so that in minimally invasive hand Tumour and background are imaged in real time in art, in the case that doctor can not row palpation assist doctor's precise positioning borderline tumor, Small metastatic lesion is detected, doctor is facilitated to position lesion, auxiliary operation.
The utility model is further described in the following with reference to the drawings and specific embodiments.
Description of the drawings
Fig. 1 is the explosive view for the imaging device performed the operation for molecular image;
Fig. 2 is the stereogram for the imaging device performed the operation for molecular image;
Fig. 3 is the schematic diagram for the imaging device performed the operation for molecular image.
Reference numeral
10 shell, 11 accommodating chamber
12 left housing, 121 connection part
1211 adjustment hole, 13 right shell
131 first mounting bracket, 1311 first through hole
132 second mounting bracket, 1,321 second through-hole
14 decoration panel, 15 deckboard
20 camera module, 21 color camera
22 fluorescence camera, 30 light splitting piece
40 connection seat, 41 hollow cavity
Through-hole after 42 front through hole 43
45 round hole of through-hole on 44
50 filter component, 51 first convex lens
52 second convex lens, 53 first filter piece
54 second filter piece, 60 thang-kng component
61 lantern ring, 62 thang-kng part
621 light hole, 70 light splitting piece regulating mechanism
71 light splitting piece mounting disc, 72 adjusting bracket
Pipe coupling head is peeped in 73 light splitting piece angle adjustment plates 80
90 host computer, 100 laser generator
120 0 type sealing ring of pipe is peeped in 110
130 data lines
Specific implementation mode
In order to more fully understand the technology contents of the utility model, with reference to specific embodiment to the skill of the utility model Art scheme is further described and illustrates, but not limited to this.
Such as Fig. 1 to Fig. 3, shown in specific embodiment, the utility model is used for the imaging device of molecular image operation, including Shell 10, interior be equipped with of shell 10 accommodate camera module 20, light splitting piece 30, connection seat 40, filter component 50 and thang-kng component 60 Accommodating chamber 11;Thang-kng component 60 is coupled with filter component 50 by connection seat 40 and positioned at the front end of filter component 50, connection seat 40 are equipped with hollow cavity 41, and front through hole 42, rear through-hole 43 and the upper through-hole 44 communicated with hollow cavity 41;Light splitting piece 30 is fixed on connection The left or right side of joint chair 40 (in the present embodiment, light splitting piece 30 is fixed on the left side of connection seat 40);Camera module 20 includes setting In the color camera 21 of vertical direction and the fluorescence camera 22 of horizontal direction.
Specifically, as shown in Fig. 1 to Fig. 2, imaging device further includes the light splitting piece regulating mechanism for fixing light splitting piece 30 70;Light splitting piece regulating mechanism 70 includes light splitting piece mounting disc 71, adjusting bracket 72 and light splitting piece angle adjustment plate 73.Connection seat 40 Left side is equipped with the round hole 45 for installing light splitting piece mounting disc 71, and light splitting piece 30 is fixed on the outside of light splitting piece mounting disc 71, Light splitting piece mounting disc 71 is clamped with adjusting bracket 72 and positioned at 72 inside of adjusting bracket, adjusting bracket 72 and light splitting piece angular adjustment Plate 73 is fixedly connected and positioned at 73 inside of light splitting piece angle adjustment plate.
Preferably, light splitting piece 30 is installed in 45 ° in light splitting piece mounting disc 71, for reflecting normal light in vertical direction Line, transmits the red-light spectrum of 800nm in the horizontal direction, and is imaged on fluorescence camera 22.Light splitting piece angle adjustment plate 73 is used In adjustment light splitting piece angle, to ensure that color camera 21 is consistent with 22 imaging effect of fluorescence camera.
Specifically, as shown in Fig. 1 to Fig. 2, shell 10 includes left housing 12 and right shell 13;Connection seat 40 is fixed on right shell 13; Right shell 13 is equipped with the first mounting bracket 131 for fixing color camera 21 and the second installation branch for fixing fluorescence camera 22 Frame 132;Left housing 12 is equipped with the connection part 121 for fixing light splitting piece angle adjustment plate 73;Connection part 121 is equipped with to be divided for adjusting The adjustment hole 1211 of 30 angle of mating plate.
Wherein, it is equipped with the decoration panel 14 being clamped with right shell 13 in 13 outside of right shell.It is equipped in 12 outside of left housing for hiding The deckboard 15 for keeping off connection part 121 prevents dust or water from entering in shell 10 from adjustment hole 1211.
Specifically, as shown in Fig. 1 to Fig. 2, filter component 50 includes the first convex lens 51, the filter of the second convex lens 52, first Eyeglass 53 and the second filter piece 54.First convex lens 51 is set to the front through hole 42 of connection seat 40 and couples with thang-kng component 60;The One filter piece 53 is set to the upper through-hole 44 of connection seat 40 and couples with the first mounting bracket 131;Second convex lens 52, the second filter Piece 54 is set to the rear through-hole 43 of connection seat 40 and couples with the second mounting bracket 132.
Specifically, as shown in Fig. 1 to Fig. 2, the first mounting bracket 131 couples with connection seat 40 and positioned at the upper of connection seat 40 End is equipped with O-ring seal 120 between the first mounting bracket 131 and connection seat 40, for preventing divergence of beam, the first installation Holder 131 is equipped with first through hole corresponding with upper through-hole 44 1311.Second mounting bracket 132 couples and is located at connection seat 40 The rear end of connection seat 40 is equipped with 0 type sealing ring 120, for preventing light from sending out between the second mounting bracket 132 and connection seat 40 It dissipates, the second mounting bracket 132 is equipped with second through-hole 1321 corresponding with rear through-hole 43;Second convex lens 52 is located at the second filter 54 front end of piece;Second convex lens 52 is identical as 54 diameter of the second filter piece.
Specifically, as shown in Fig. 1 to Fig. 2, thang-kng component 60 includes lantern ring 61 and the thang-kng part 62 coupled with lantern ring 61, leads to Light part 62 is located at the rear end of lantern ring 61;Thang-kng part 62 be equipped with light hole 621 corresponding with front through hole 42, thang-kng part 62 with couple Seat 40 couples, and 0 type sealing ring 120 is equipped between thang-kng part 62 and connection seat 40, for preventing divergence of beam.
Wherein, the imaging device further include in peep pipe coupling head 80, inside peep pipe coupling head 80 and couple and be located at lantern ring 61 61 front end of lantern ring.
Specifically, such as Fig. 1 to Fig. 2, which is additionally provided with data line 130 so that camera module 20 was shot Image information is convenient for transmission.
As shown in figure 3, the utility model additionally provides the imaging device performed the operation for molecular image, including above-mentioned imaging Device and the host computer 90 being electrically connected with camera module 20, laser generator 100 and interior peep pipe 110;Laser generator 100 It is connect with the interior progress of pipe 110 light path of peeping;Pipe 110 is inside peeped to peep pipe coupling head 80 with interior and couple.Host computer 90 is for handling from coloured silk The coloured image and IR fluorescence image that form and aspect machine 21, fluorescence camera 22 receive, and carry out calculating combination so that in minimally invasive hand Tumour and background are imaged in real time in art, in the case that doctor can not row palpation assist doctor's precise positioning borderline tumor, Small metastatic lesion is detected, doctor is facilitated to position lesion, auxiliary operation.
Wherein, the power of laser generator 100 is 2W, and for generating dedicated near infrared spectrum.
The imaging device needs to coordinate molecular fluorescence dyestuff drug indocyanine green (abbreviation ICG).First ICG is injected when use To patient's body, ICG meetings are automatic and tumor focus outside generates certain protein targets or the target of enzyme molecule combines.ICG exists After being combined with these targets, about 800 nanometers of near infrared light can be launched under the excitation of near infrared light.The imaging device exists Tumour and background are imaged in real time in the Minimally Invasive Surgery of the tumor resections such as lung cancer, liver cancer, doctor can not row palpation situation Lower auxiliary doctor precise positioning borderline tumor detects small metastatic lesion, and to two-way colour and fluorescent image fusion display, side Just doctor positions lesion, auxiliary operation.
The utility model additionally provides a kind of light-splitting method of Image Acquisition, by the thang-kng for being fixed on 40 front end of connection seat Component 60 acquires light source, detaches light source using light splitting piece 30, is transmitted to the color camera for being fixed on 40 vertical direction of connection seat respectively 21 and horizontal direction fluorescence camera 22, be transmitted to color camera 21 in vertical direction reflection ordinary ray, horizontal direction transmission is close Infrared light is transmitted to fluorescence camera 22;When light splitting piece 30 does not reach expected spectrophotometric result, light splitting piece angle is unclamped with tool first Adjustable plate 73 is spent, adjustment hole 1211 is inserted into using ellipse tool stick, rotates adjusting bracket 72, light splitting piece 30 is adjusted to required After angle, ellipse tool stick is taken out from adjustment hole 1211, then light splitting piece angle adjustment plate 73 is fastened with tool.
In conclusion the utility model passes through camera module, light splitting piece, connection seat, the filter in housing accommodating chamber Component and thang-kng component, thang-kng component are coupled with filter component by connection seat and positioned at the front ends of filter component, and light splitting piece is solid Due to the left side of connection seat;Color camera, fluorescence camera and host computer are electrically connected, and laser generator carries out light with interior pipe of peeping Road connects, and inside peeps pipe and peeps pipe coupling head with interior and couple;Light source is detached using light splitting piece, is transmitted in vertical direction reflection ordinary ray Color camera, horizontal direction transmission near infrared light are transmitted to fluorescence camera;Host computer is for handling from color camera, fluorescence camera The coloured image and IR fluorescence image received, and carry out calculating combination so that in real time to tumour and the back of the body in Minimally Invasive Surgery Scape is imaged, in the case that doctor can not row palpation assist doctor's precise positioning borderline tumor, detect small metastatic lesion, side Just doctor positions lesion, auxiliary operation.
The above-mentioned technology contents that the utility model is only further illustrated with embodiment, in order to which reader is easier to understand, But the embodiment for not representing the utility model is only limitted to this, and any technology done according to the utility model extends or recreation, Protected by the utility model.The scope of protection of the utility model is subject to claims.

Claims (9)

1. for the imaging device of molecular image operation, including shell, which is characterized in that it is equipped in the shell and accommodates camera mould The accommodating chamber of group, light splitting piece, connection seat, filter component and thang-kng component;The thang-kng component passes through the connection seat and filter Mirror assembly couple and positioned at filter component front end, the connection seat be equipped with hollow cavity, and communicated with hollow cavity front through hole, after Through-hole and upper through-hole;The light splitting piece is fixed on the left or right side of connection seat;The camera module includes being set to vertical direction Color camera and horizontal direction fluorescence camera.
2. the imaging device according to claim 1 for molecular image operation, which is characterized in that the imaging device Further include the light splitting piece regulating mechanism for fixing light splitting piece, the light splitting piece regulating mechanism includes light splitting piece mounting disc, adjusts Holder and light splitting piece angle adjustment plate;The light splitting piece mounting disc couples with connection seat, and the light splitting piece is fixed on light splitting piece peace On the outside of sabot, the light splitting piece mounting disc is clamped with adjusting bracket and on the inside of adjusting bracket, the adjusting bracket and light splitting Piece angle adjustment plate is fixedly connected and on the inside of light splitting piece angle adjustment plate.
3. the imaging device according to claim 1 for molecular image operation, which is characterized in that the shell includes a left side Shell and right shell;The connection seat is fixed on right shell;The right shell is equipped with the first mounting bracket and use for fixing color camera In the second mounting bracket of fixed fluorescence camera;The left housing is equipped with the connection part for fixing light splitting piece angle adjustment plate;Institute Connection part is stated equipped with the adjustment hole for adjusting light splitting piece angle.
4. the imaging device according to claim 3 for molecular image operation, which is characterized in that the filter component packet Include the first convex lens, the second convex lens, the first filter piece and the second filter piece;First convex lens is set to the preceding logical of connection seat Hole and couple with thang-kng component;The first filter piece is set to the upper through-hole of connection seat and couples with the first mounting bracket;It is described Second convex lens, the second filter piece are set to the rear through-hole of connection seat and couple with the second mounting bracket.
5. the imaging device according to claim 4 for molecular image operation, which is characterized in that the first installation branch Frame couples with connection seat and positioned at the upper end of connection seat, it is logical that first mounting bracket is equipped with corresponding with upper through-hole first Hole.
6. the imaging device according to claim 4 for molecular image operation, which is characterized in that the second installation branch Frame couples with connection seat and positioned at the rear end of connection seat, it is logical that second mounting bracket is equipped with corresponding with rear through-hole second Hole;Second convex lens is located at the second filter piece front end;Second convex lens is identical as the second filter optic diameter.
7. the imaging device according to claim 1 for molecular image operation, which is characterized in that the thang-kng component packet The thang-kng part for including lantern ring and coupling with lantern ring, the thang-kng part are located at the rear end of lantern ring;The thang-kng part is equipped with and front through hole phase Corresponding light hole, the thang-kng part couple with connection seat.
8. the imaging device according to claim 1 for molecular image operation, which is characterized in that the imaging device Peep pipe coupling head in further including, it is described in peep pipe coupling head and couple with lantern ring and positioned at lantern ring front end.
9. the imaging device for molecular image operation, which is characterized in that including the imaging described in claim 1-8 any one Device and the host computer being electrically connected with camera module, laser generator and interior peep pipe;The laser generator peeps pipe with interior Carry out light path connection;Pipe is peeped in described to peep pipe coupling head with interior and couple.
CN201720272519.4U 2017-03-20 2017-03-20 Imaging device and equipment for molecular image operation Active CN207734155U (en)

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Application Number Priority Date Filing Date Title
CN201720272519.4U CN207734155U (en) 2017-03-20 2017-03-20 Imaging device and equipment for molecular image operation

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Application Number Priority Date Filing Date Title
CN201720272519.4U CN207734155U (en) 2017-03-20 2017-03-20 Imaging device and equipment for molecular image operation

Publications (1)

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CN207734155U true CN207734155U (en) 2018-08-17

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106821330A (en) * 2017-03-20 2017-06-13 深圳市和虎科技有限公司 For the imaging device and equipment of molecular image operation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106821330A (en) * 2017-03-20 2017-06-13 深圳市和虎科技有限公司 For the imaging device and equipment of molecular image operation

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Date Code Title Description
GR01 Patent grant
GR01 Patent grant
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20190124

Address after: 100176 Beijing Economic and Technological Development Zone

Patentee after: Beijing digital precision medical technology Co., Ltd.

Address before: 518000 Shenzhen Nanshan District, Shenzhen Province, Guangdong Province, No. 6 YuexingErdao, Wuhan University, Shenzhen Industry, Education and Research Building B212

Patentee before: SHENZHEN HOPEFUL TECHNOLOGY CO., LTD.