CN2077126U - Intelligence blood platelet gathering instrument - Google Patents
Intelligence blood platelet gathering instrument Download PDFInfo
- Publication number
- CN2077126U CN2077126U CN 90207370 CN90207370U CN2077126U CN 2077126 U CN2077126 U CN 2077126U CN 90207370 CN90207370 CN 90207370 CN 90207370 U CN90207370 U CN 90207370U CN 2077126 U CN2077126 U CN 2077126U
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- CN
- China
- Prior art keywords
- circuit
- key
- intelligent
- amplifier
- platelet aggregation
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
The utility model relates to an intelligent blood platelet gathering instrument which is an instrument for measuring blood platelet in a human body. The utility model is composed of a power source, a temperature control circuit, a photoelectric conversion circuit, an amplification circuit, a program control amplification circuit, an analogue-digital conversion circuit, a data conversion circuit, an input and output circuit, a display, a keyboard, a printer, an agitating electrical machine and a basic calculation system. An octet microprocessor is used as a CPU to control each part of the utility model. The utility model has the functions of blood measurement, automatic zero adjustment, agitation, report printing, time display, etc.
Description
The utility model is a hematoblastic Medical Instruments in the testing human blood, is a kind of Medical Instruments that adopts the near infrared light turbidimetry to record hematoblastic adhesion and aggregation capability specifically.
The present U.S. a kind of CHRONO-LOG type platelet aggregation instrument, be unicity, no computer controller needs manual zeroing, amplitude modulation, starts stirring machine in the use, need to prepare separately registering instrument simultaneously, registering instrument is finished merely and is assembled describing of curve, manually calculate according to curve, make laboratory report, can not do the experiment report automatically, blood using amount is big, and constant temperature is long preheating time before the test.
The utility model provides a kind of employing micro computer special circuit various corresponding control programs is solidificated in the integrated circuit, solves automatic zero set (AZS), and different specimen blood plasma is carried out automatic zero set (AZS); Automatically drive stirring motor, and a kind of intelligent platelet aggregation instrument that the gathering curve and the laboratory report of test can be printed automatically, duplicated and show the time at that time automatically.Blood using amount also is less than prior art simultaneously.
For finishing the technical scheme that above-mentioned purpose is taked: whole instrument adopts 8-bit microprocessor Z80 to make central processing unit, and the work of control instrument each several part is carried out calculation process to signal, and whole instrument is worked under system controlled by computer automatically.Adopt modulus and digital-to-analog conversion in the circuit, program control amplification is returned to zero automatically and is transferred gain.
The utility model is made up of power supply, temperature-adjusting circuit, photoelectric switching circuit, amplifying circuit, programmable amplifying circuit, analog to digital conversion circuit, D/A converting circuit, imput output circuit, display, keyboard, printer, stirring motor and basic calculating system.
Power unit be with obtain after the voltage stabilizer voltage stabilizing behind the 220V rectifying and wave-filtering 5V, 10V and ± the 15V direct supply makes the working power of instrument.The circuit of temperature control part is established calibration cell, establishes heat sensitive sensor in the groove, and the opening and closing by the temperature signal of gathering amplifies back control electric heater make calibration cell remain on 37 ℃, and in ± 0.1 ℃, the square cup of blood plasma is put into calibration cell.Photoelectric conversion section is arranged at the calibration cell front end, is made up of infraluminescence pipe and light-sensitive cell, and infrared light sees through square test glass, by the light-sensitive cell output voltage, takes place to change accordingly.Amplifier section is made up of two-level operating amplifier, and the voltage that light-sensitive cell is exported amplifies output.Program control amplifier section is made up of operational amplifier and feedback resistive network, select feedback resistance by multi-way switch, the closed loop gain of control amplifier, the laggard stroke control of signal subtraction of the output of the amplifying circuit of prime and digital-to-analog circuit output is amplified, and outputs to the analog to digital conversion part.The analog to digital conversion part is made up of eight A/D change-over circuits, and this part converts aanalogvoltage to digital quantity and exports under central processing unit control.D/A converting circuit partly is to convert the central processing unit supplied with digital signal to aanalogvoltage output, goes into program control amplifier section.Input is interface and the buffering of central processing unit to the input and output between display, printer, stirring motor, A/D and D/A, the program control amplification, wherein is made up of two Z80P10 a slice 74LS273.The display part is made up of four LED charactrons and six light emitting diodes, is used for duty, partial data and the clock of display instrument.Keyboard portion is touched key by 7 and is formed, and is used for to the central processing unit input control order.Printing portion adopts the PP40 plotting apparatus, the output test report.Stirring motor is used to rotate the usefulness that test glass produces stirring.The basic computer system is made up of central processing unit, clock circuit, decoding scheme, memory under program ROM, data memory RAM, all above-mentioned program Solidifications are in a slice EPROM, central processing unit follow procedure and key instruction step-by-step operation, the coordinated operation of control each several part, clock circuit provides synchronizing clock signals for central processing unit.
The utility model embodiment is described in detail in conjunction with the accompanying drawings.
Fig. 1 is the utility model work block diagram;
Fig. 2 is the utility model amplification grade circuit figure;
Fig. 3 is the utility model main circuit diagram.
Form by power supply, temperature control, opto-electronic conversion, amplification, program control amplification, analog to digital conversion, digital-to-analog conversion, input and output interface, demonstration, keyboard, printer, stirring motor and basic computer system according to complete machine shown in Figure 1, wherein the basic computer system is made up of central processing unit Z80ACPU, clock circuit, decoding scheme, memory under program ROM, data memory RAM, and all program Solidifications are in a slice 2764EPROM.Wherein power supply is with the 220V transformation, rectifier filer, with 78,79 serial voltage stabilizer voltage stabilizings obtain+5V ,+10V and ± the 15V direct supply is the working power of instrument.
The temperature-adjusting circuit utilization is installed in the heat sensitive sensor collecting temperature signal in the calibration cell, amplify opening or closing of back control electric heater, calibration cell is remained in 37 ℃ ± 0.1 ℃, two electric heater 220V alternating current Fast Heating that insert in parallel during start, to the conducting of 37 ℃ of circuit commentaries on classics triggering one-way SCRs, pilot relay makes the power of well heater reduce to 1/4 the electric heater series connection, circuit according to the height of temperature through amplifier relatively after the opening or closing of control bidirectional triode thyristor, temperature is controlled at about 37 ℃.Test tube is put into calibration cell.
Photoelectric switching circuit is made up of infraluminescence pipe BT401 and light-sensitive cell 2CR21.When the intensity that shines through sample on the light-sensitive cell, when changing according to the sample transmission change, light-sensitive cell output voltage generation respective change as shown in Figure 2.
Amplifying circuit as shown in Figure 2, by one-level amplifier OP07IC
1With one-level amplifier IC
23140 and resistance R
1～R
9, variable resistor W
1～W
3, capacitor C
1～C
5The two-stage amplifier of forming is that photronic output is amplified, and amplifying signal is sent into programmable amplifying circuit.
Programmable amplifying circuit as shown in Figure 2, by a slice amplifier IC
33140 and feedback resistive network IC
184051 and resistance R
10～R
24, variable resistor W
4, capacitor C
6And C
7, IC
18Comprise eight groups of switches compositions, central processing unit is selected feedback resistance by eight way switch, the closed loop gain of control amplifier, the input end of programmable amplifier circuit connects the output terminal and the output of D/A converter level of preamplifying circuit, amplify after this two paths of signals subtracts each other and export, link to each other with analog to digital converter.
Analog to digital conversion circuit is by ic chip
90,809 eight A/D change-over circuit, peripheral circuit IC
8, IC
9Form, under central processing unit control, convert aanalogvoltage to digital quantity and export.
D/A converting circuit is by IC
50808 and IC
63140 and resistance R
41, capacitor C
8Forming, is the digital signal switch analog voltages that central processing unit is sent into, and is input to programmable amplifier.
Input/output interface circuit is by two Z80P10IC
10, IC
11Form, be used for the IO interface between central processing unit and keyboard, display printer, stirring motor, A/D and D/A converter, the programmable amplifier.
Display is by four LED charactrons and six light emitting diodes, IC
4Driving circuit, eight triodes, resistance R
25～R
32Form, this part is used for duty, partial data and the clock of instrument.
Keyboard is by reset key RESET, platelet rich plasma key PRP, platelet poor plasma key PPP, start key START, printing key PRINT, time key TIME and proofread and correct AMEND totally seven keys, forms, and is used to import the central processing unit steering order.
Printer is made up of the PP40 plotting apparatus, is used for the output test report, and finishes record real-time aggregation curve.
Stirring motor: magnet steel is housed on motor shaft, during the motor rotation, the rotating magnetic field of utilizing rotary magnetic steel to produce, the magnetic bead that rotates in the test glass produces stirring, and central processing unit sends respective drive signal and drives stirring motor under programmed control.
The basic computer system is by central processing unit Z80IC
15, clock circuit 4020, IC16,74LS74, IC17, decoding scheme 74LS138 IC13, memory under program ROM1/474LS32IC14, data memory RAM6116IC
12Form, all program Solidifications do not need data file in a slice 2764EPROM, and reliable operation, program are difficult for losing, central processing unit follow procedure and keyboard instruction step-by-step operation, and the control each several part is coordinated moving row, and clock circuit is the central processing unit synchronizing clock signals.
Operating process:
After the start, temperature-adjusting circuit and computer system are promptly started working, and display read clock, printer, stirring motor all are in standby condition, and CPU sampling keyboard is waited for the key order, after waiting to enter temperature constant state, can experimentize.
After keying in " RESET " order order, the coordinate of CPU control plotting apparatus curve plotting, and wait for next key order.
After in prospect hole, putting into platelet poor plasma, key in " PPP " order, CPU is to D/A circuit output reference voltage signal, at programmable amplifier input end and PPP signal subtraction through amplifying, by sampling one by one through the programmable amplifier output and the adjustment reference voltage of A/D circuit conversion, make programmable amplifier be output as zero, reach the zeroing purpose, repeat said process, one group of reference voltage value in the time that different gains can being obtained after adjusting amplifier gain.After noting this group numerical value after zeroing finishes, show on the display " 0 " that expression is carried out " PPP " order (zeroing) and finished.
After changing platelet rich plasma and keying in " PRP " order, CPU places 1:1 shelves and the zeroing reference voltage when D/A exports this gain with the programmable amplifier gain, sampling programmable amplifier output at this moment again, voltage is because the transmittance of blood platelet amount and serum has certain relation, so CPU proofreaies and correct through computing and with software and obtains platelet count, CPU send demonstration and record for printing laboratory report these data, after obtaining platelet count, CPU adjusts programme-controlled gain, and export corresponding reference voltage, make the output (i.e. the PRP signal of Fang Daing) of programmable amplifier reach 2.5V～4.0V, to make full use of the resolution of the total sheet of A/D, after adjusting end, to PIO(1) A.7 mouth send a high level, start stirring motor, after splashing into reagent, blood sample is under the reagent effect, assemble, become clear transmittance and aggregation rate with certain relationship change key in " START " order after, CPU continuous sampling after 1 second is assembled signal 10 times, convert aggregation rate to through the laggard row operation of digital filtering, record also converts coordinate figure in real time to and outputs to plotting apparatus and draw to assemble curve, and CPU carries out minute counting down simultaneously, and send display to show, after counter reduces to zero, stop the A/D sampling, close stirring motor, and calculate one minute escalating rate, and every gathering, the depolymerization index is printed laboratory report.
After experiment finishes, key in " PRINT " order after, CPU with preserve among the RAM, sampled value accesses, and repaints curve and laboratory report.Key in " TIME " and reach the interior clock of the adjustable complete machine of " AMEND " order, clock is with behind the synchronous clock frequency dividing of a slice CC4020 ten level Four counters to CPU, be input to the non-shielding interrupting input end of CPU, constitute year, month, day, hour, min, second, numeration by the software register.
All computings, operation is finished by the programmed control CPU that resides among the EPROM.
Claims (7)
1, a kind of employing infrared light turbidimetry is surveyed hematoblastic adhesion and gathering, and the intelligent platelet aggregation instrument by warm groove, opto-electronic conversion, power supply, main frame, printing and registering instrument are formed is characterized in that: a.Photoelectric switching circuit is made up of infraluminescence pipe BT401, light-sensitive cell 2CR21, and light-sensitive cell 2CR21 output connects amplifier unit OP07IC, and input end is through second level 3140IC
2After the amplification, connect 3140IC in D/A converter and the program control amplifier unit respectively
3Input end, 3140IC
3Input end connect 4051 resistor network IC18 simultaneously and comprise eight groups of switches, 3140IC3 output connects A/D converter, above-mentioned A/D, D/A converter and IC18 all are connected with central processing unit; B. establish input/output interface circuit between central processing unit and keyboard, display, printer, stirring machine and A/D and D/A converter, the program control amplifier unit; C. central processing system is made up of central processing unit, clock circuit, decoding scheme, memory under program ROM, data memory RAM, and is solidificated among a slice EPROM.
2, intelligent platelet aggregation instrument according to claim 1 is characterized in that the two-stage amplifier that amplifier unit is made up of one-level amplifier OP07IC1 and one-level amplifier 3140IC2 and resistance R 1～R9, variable resistor V1～W3, capacitor C 1～C5.
3, intelligent platelet aggregation instrument according to claim 1 is characterized in that program control amplifier unit comprises that by a slice amplifier 3140IC3 and feedback resistive network 4051IC18 and resistance R 10～R24, variable resistor W4, capacitor C 6 and C7IC18 eight groups of switches form.
4, intelligent platelet aggregation instrument according to claim 1 is characterized in that D/A converting circuit is made up of integrated package 0808IC5,3140IC6 and resistance R 41 capacitor C 8.
5, intelligent platelet aggregation instrument according to claim 1 is characterized in that input/output interface circuit is made up of two Z80P10 of IC10, IC11.
6, intelligent platelet aggregation instrument according to claim 1 is characterized in that display is made up of four LED charactrons and six light emitting diodes, IC474LS273, eight triodes, resistance R 25～R32.
7, intelligent platelet aggregation instrument according to claim 1 is characterized in that keyboard is made up of the greedy blood platelet blood plasma key of RESET reset key, PRP platelet rich plasma key, PPP, START start key, PRINT printing key, TIME time key and AMEND check key.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 90207370 CN2077126U (en) | 1990-06-25 | 1990-06-25 | Intelligence blood platelet gathering instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 90207370 CN2077126U (en) | 1990-06-25 | 1990-06-25 | Intelligence blood platelet gathering instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2077126U true CN2077126U (en) | 1991-05-15 |
Family
ID=4887809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 90207370 Withdrawn CN2077126U (en) | 1990-06-25 | 1990-06-25 | Intelligence blood platelet gathering instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2077126U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102023221A (en) * | 2009-09-15 | 2011-04-20 | 北京普利生仪器有限公司 | Quality control experimental method for full-automatic platelet aggregation instrument |
| CN101881737B (en) * | 2009-05-06 | 2011-08-10 | 北京普利生仪器有限公司 | Method and device for testing platelet aggregation |
| CN104281079A (en) * | 2014-10-16 | 2015-01-14 | 北京北大明德科技发展有限公司 | Light transmittance electrical control detection system and device with same |
-
1990
- 1990-06-25 CN CN 90207370 patent/CN2077126U/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101881737B (en) * | 2009-05-06 | 2011-08-10 | 北京普利生仪器有限公司 | Method and device for testing platelet aggregation |
| CN102023221A (en) * | 2009-09-15 | 2011-04-20 | 北京普利生仪器有限公司 | Quality control experimental method for full-automatic platelet aggregation instrument |
| CN104281079A (en) * | 2014-10-16 | 2015-01-14 | 北京北大明德科技发展有限公司 | Light transmittance electrical control detection system and device with same |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |