CN207610910U - A kind of spinal cord imbedded mold - Google Patents
A kind of spinal cord imbedded mold Download PDFInfo
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- CN207610910U CN207610910U CN201721800287.1U CN201721800287U CN207610910U CN 207610910 U CN207610910 U CN 207610910U CN 201721800287 U CN201721800287 U CN 201721800287U CN 207610910 U CN207610910 U CN 207610910U
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- forming part
- pedestal
- spinal cord
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- cavity
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Abstract
The utility model is related to biological tissue embedding technical field more particularly to a kind of spinal cord imbedded molds.Spinal cord imbedded mold provided by the utility model includes specimen tube and pedestal shaping mechanism, pedestal shaping mechanism is arranged in one end of specimen tube, pedestal shaping mechanism includes the first forming part and the second forming part, first forming part and the second forming part energy dismantling connection and collectively form pedestal forming cavity, pedestal forming cavity is connected with the inner cavity of specimen tube, and the cross-sectional area of inner cavity is less than the cross-sectional area of pedestal forming cavity.Since the first forming part and the second forming part are split, the technical issues of sample can take out from the opening of pedestal forming cavity, and the coronal section sample and sagittal slices sample so as to solve myeloid tissue are difficult to be removed from the molds.In addition, the sample pedestal of the comparatively large cross-sectional area obtained by pedestal forming cavity, can play sample preferable supporting role, solve the problems, such as that the coronal section sample of myeloid tissue and sagittal slices sample support effect are poor.
Description
Technical field
The utility model is related to biological tissue embedding technical field more particularly to a kind of spinal cord imbedded molds.
Background technology
Quick diagnosis is carried out to pathology through coming frequently with frozen section technique in operation.Frozen section is one kind in low temperature item
Tissue is set to be cooled fast to certain degree of hardness under part, the method being then sliced, key step includes：Draw materials, is fixed, embedding,
Slice and dyeing.Wherein, embedding step is specially：After biological tissue is put into imbedded mold, added in imbedded mold appropriate
Embedding medium (such as：Paraffin, gelatin etc.) infiltration biological tissue, then imbedded mold is placed on freezing stage and is freezed 10 minutes or so,
Obtain the biological tissue specimens Jing Guo embedding treatment.
When making myeloid tissue's sample for coronal section and sagittal slices, it will usually using the knot with myeloid tissue
Structure and the compatible circular tube shaped imbedded mold of size embed myeloid tissue, but circular tube shaped imbedded mold internal cavity
Cross-sectional area is smaller, so operator is difficult to take out sample from imbedded mold.In addition, due to by above-mentioned imbedded mold at
The base area for myeloid tissue's sample that type goes out is also smaller, cannot achieve and is preferably supported to sample, is unfavorable for operator to mark
This is cut.
Utility model content
The purpose of this utility model is that proposing a kind of spinal cord imbedded mold, which facilitates the section preparation of myeloid tissue
It is removed from the molds and conducive to the support to section preparation.
For this purpose, the utility model uses following technical scheme：
One end of a kind of spinal cord imbedded mold, including specimen tube, the specimen tube is provided with pedestal shaping mechanism, the bottom
Seat shaping mechanism includes the first forming part and the second forming part, first forming part and the second forming part energy dismantling connection
And pedestal forming cavity is collectively formed, the pedestal forming cavity is connected with the inner cavity of the specimen tube, the cross section of the inner cavity
Cross-sectional area of the product less than the pedestal forming cavity.
Further, first forming part and second forming part are the shell with opening, one of institute
Shell is stated to be arranged in the opening of another shell.
Further, one in first forming part and second forming part is the shell with opening, another
A is mounting plate, and the mounting plate is arranged in the opening of the shell.
Further, the side wall of the shell is inwardly provided with position limiting structure, the mounting plate and the position limiting structure phase
It abuts, the height of the position limiting structure is identical as the height of pedestal forming cavity.
Further, circumferentially spaced set has multiple position limiting structures to the side wall.
Further, the mounting plate is interference fitted with the shell.
Further, first forming part is integrally formed with the specimen tube or can dismantling connection；Or,
Second forming part is integrally formed with the specimen tube or can dismantling connection.
Further, first forming part is connected with the specimen tube, and second forming part is rotatably connected to drawing
Ring.
Further, the outer surface of second forming part offers holding tank, and the draw ring is accommodated in the holding tank
It is interior.
Further, the specimen tube and the pedestal shaping mechanism are by polypropylene, acrylic plastics and/or silica gel system
At.
The beneficial effects of the utility model are：
Spinal cord imbedded mold provided by the utility model includes specimen tube and pedestal shaping mechanism, the setting of pedestal shaping mechanism
In one end of specimen tube, pedestal shaping mechanism includes the first forming part and the second forming part, the first forming part and the second forming part
Dismantling connection and pedestal forming cavity can be collectively formed, pedestal forming cavity is connected with the inner cavity of specimen tube, the cross-sectional area of inner cavity
Less than the cross-sectional area of pedestal forming cavity.The utility model is detachably connected and jointly by the first forming part and the second forming part
Pedestal forming cavity is constituted, and the cross-sectional area of inner cavity is less than the cross-sectional area of pedestal forming cavity, when the coronal section of myeloid tissue
After the completion of sample and sagittal slices preparation of specimen, the first forming part and the second forming part can be split, and by sample from cross
The opening of the larger pedestal forming cavity of sectional area is taken out, and coronal section sample and sagittal so as to solve myeloid tissue are cut
The technical issues of piece sample is difficult to be removed from the molds.Further, since manufactured sample includes molding first by specimen tube
Point, further include by the molding second part of pedestal forming cavity, and the cross-sectional area of second part is more than the cross section of first part
Product, the second part of comparatively large cross-sectional area can play sample preferable supporting role, can solve the coronal of myeloid tissue
The problem of section preparation and sagittal slices sample support effect difference.
Description of the drawings
Fig. 1 is the installation diagram for the spinal cord imbedded mold that embodiment one provides；
Fig. 2 is the front view for the spinal cord imbedded mold that embodiment one provides；
Fig. 3 is in Fig. 1 along the sectional view in the directions A-A；
Fig. 4 is the explosive view for the spinal cord imbedded mold that embodiment one provides；
The structural schematic diagram for the second forming part that Fig. 5 embodiments one provide；
The sectional view for the spinal cord imbedded mold that Fig. 6 embodiments two provide；
Fig. 7 is the structural schematic diagram for the first forming part that embodiment two provides；
Fig. 8 is in Fig. 7 along the sectional view in the directions B-B.
In figure：
1- spinal cord imbedded molds；
11- specimen tubes；12- pedestal shaping mechanisms；13- draw rings；
The inner cavities 111-；The first forming parts of 121-；The second forming parts of 122-；123- pedestal forming cavities；
1211- position limiting structures；1221- holding tanks.
Specific implementation mode
In order to enable those skilled in the art to better understand the technical solutions of the present invention, below in conjunction with the accompanying drawings and pass through
Specific implementation mode further illustrates the technical solution of the utility model.
Embodiment one
Understanding to the present embodiment for convenience, now illustrates with regard to coronal section sample and sagittal slices sample.It is coronal
Slice refers to being cut on coronal-plane to sample, and sagittal slices refer to being cut in sagittal plane to sample.Coronal-plane
Refer to the plane being made up of vertical axis and horizontal axis and all planes in parallel, for human body, coronal-plane refer to by
Longitudinal sectional human body is front and back two-part section, and in the present embodiment, vertical axis refers to the axis direction of spinal cord.Sagittal plane refers to edge
The plane and all planes in parallel that vertical axis and the longitudinal axis are constituted, for human body, sagittal plane refers to that human body is divided into a left side
Right two-part section, in the present embodiment, vertical axis refers to the axis direction of spinal cord.
Fig. 1 is the installation diagram for the spinal cord imbedded mold that embodiment one provides, and Fig. 2 is the spinal cord embedding mould that embodiment one provides
The front view of tool, Fig. 3 are along the sectional view in the directions A-A in Fig. 1, and Fig. 4 is the explosion for the spinal cord imbedded mold that embodiment one provides
Figure.In the present embodiment, as shown in figures 1-4, spinal cord imbedded mold 1 include specimen tube 11 and pedestal shaping mechanism 12, pedestal at
Type mechanism 12 is arranged in one end of specimen tube 11, and pedestal shaping mechanism 12 includes the first forming part 121 and the second forming part 122,
First forming part 121 and the second forming part 122 dismantling connection and can collectively form pedestal forming cavity 123, pedestal forming cavity 123 with
The inner cavity 111 of specimen tube 11 is connected, and the cross-sectional area of inner cavity 111 is less than the cross-sectional area of pedestal forming cavity 123.This practicality is new
Type is detachably connected and collectively forms pedestal forming cavity 123, and inner cavity 111 by the first forming part 121 and the second forming part 122
Cross-sectional area be less than pedestal forming cavity 123 cross-sectional area, when the coronal section sample and sagittal slices sample of myeloid tissue
After completing, the first forming part 121 and the second forming part 122 can be split, and sample is larger from cross-sectional area
The opening of pedestal forming cavity 123 is taken out, coronal section sample and sagittal slices sample to solve myeloid tissue be difficult to from
The technical issues of being taken out in mold.Further, since manufactured sample includes by 11 molding first part of specimen tube, further include by
123 molding second part of pedestal forming cavity, and the cross-sectional area of second part is more than the cross-sectional area of first part, larger cross
The second part of sectional area can play sample preferable supporting role, can solve myeloid tissue coronal section sample and
The problem of sagittal slices sample support effect difference.
In addition, when making cross-section slices sample, the second forming part 122 in the present embodiment can be used alone, tool
The production method of body is：Myeloid tissue is laterally placed on to the second forming part 122.So being embedded using the spinal cord in the present embodiment
The making of coronal section sample, sagittal slices sample and cross-section section preparation may be implemented in mold 1, only passes through one set of die energy
Enough making realized to different section preparations, improve the switching efficiency and producing efficiency for making different specimens.
In the present embodiment, as shown in figure 3, the first forming part 121 and the second forming part 122 are the shell with opening
Body, and the cross-sectional area of the shell of the first forming part 121 is less than the cross-sectional area of the shell of the second forming part 122, the first molding
Portion 121 is plugged in the second forming part 122.Pedestal forming cavity 123, pedestal forming cavity 123 are constituted by the cooperation of two shells
The pedestal of sample is used to support at molding.Specifically, the outer shape and size of the first forming part 121 and the second forming part
122 interior shape and size is adapted, and be can get the preferable pedestal forming cavity 123 of sealing effect, is avoided pouring into mould inside
Embedding medium leakage, reduce the waste of embedding medium, improve the utilization rate of embedding medium.Certainly, in the opening of the first forming part 121
The inside of the case lid of end and/or the second forming part 122 may be provided with the sealing structure such as rubber, can further increase bottom
The sealing effect of seat forming cavity 123.
In another embodiment, the cross-sectional area of the cavity of the first forming part 121 is more than the cavity of the second forming part 122
Cross-sectional area, the second forming part 122 is plugged in the first forming part 121, can also reach and obtain the preferable bottom of sealing effect
The effect of seat forming cavity 123.
Illustratively, in the present embodiment, the cavity of the first forming part 121 and the cavity of the second forming part 122 is transversal
Face can be circle, and the circle centre position of two circular centers of circle and the cross section of specimen tube 11 is on the same line, and the straight line
It is overlapped with the axis of specimen tube 11.In the present embodiment, spinal cord imbedded mold 1 is used to make the spinal cord sample of small white mouse, in order to
Adapt to the spinal cord shape and size of small white mouse, the outer diameter of specimen tube 11 is 12mm~18mm, the internal diameter of specimen tube 11 be 10mm~
The outer diameter of 15mm, the first forming part 121 are 16mm, and the internal diameter of the first forming part 121 is 14mm, the height of the first forming part 121
Outer diameter for 14mm~22mm, the second forming part 122 is 18mm, and the internal diameter of the second forming part 122 is 16mm, is highly 8mm.When
So, the cross section of the cavity of the first forming part 121 and the cavity of the second forming part 122 can also be rectangular or other shapes.
In order to adapt to different plant species spinal cord shape and size, specimen tube 11, the first forming part 121 and the second forming part 122 ruler
It is very little to be adjusted according to the shape of different spinal cords and size.
In the present embodiment, specifically, the height of pedestal forming cavity 123 is 5mm~30mm, the bottom molded can be made
Seat has certain thickness, to realize to the preferable support effect of sample.In the present embodiment, the height of pedestal forming cavity 123
It refer to the height of the shell of the first forming part 121.In another embodiment, when the second forming part 122 is plugged on the first molding
When in portion 121, the height of pedestal forming cavity 123 refers to the height of the second forming part 122.
In the present embodiment, the amount of pouring into of embedding medium in mold is poured into order to facilitate observation, the first forming part 121 and the
Two forming parts 122 can be made of clear material, and be provided with scale value in the first forming part 121 or the second forming part 122,
The convenient control for pouring into the embedding dosage in mold.Specifically, specimen tube 11, the first forming part 121 and second are molded
Portion 122 is made of polypropylene, acrylic plastics or silica gel.Inner wall using the mold of polypropylene material is more smooth, ensures ridge
The sample of myeloid tissue can be smoothly removed from the molds.Had using mold made of acrylic plastics or silica gel preferable tough
Property so that mold is still flexible after frost, and there is preferable durability, the person of being conveniently operated to use Mold Making myeloid tissue
Sample.
In the present embodiment, specimen tube 11 and the first forming part 121 are integrally formed, and can effectively reduce specimen tube 11 and the
The molding die of one forming part 121 improves the shaping efficiency of specimen tube 11 and the first forming part 121.Certainly, in other embodiment
In, specimen tube 11 and the first forming part 121 can be connected through a screw thread or fastener is realized and fixed, when specimen tube 11 or the first
After one in forming part 121 damage, the part of damage is only replaced, without by specimen tube 11 and the first forming part
121 replace together, reduce maintenance cost.
Fig. 5 is the structural schematic diagram for the second forming part that embodiment one provides.In the present embodiment, as shown in figure 5, second
Rotation is provided with draw ring 13 in forming part 122, and after the completion of sample is molded, operator holds the outer tube of specimen tube 11 on the other hand,
Another pulls draw ring 13, and two hands exert a force to opposite both direction, to realize the demoulding of sample.Specifically, the
The outer surface of two forming parts 122 offers holding tank 1221, and draw ring 13 is provided in holding tank 1221, when spinal cord imbedded mold 1
And internal sample is when carrying out freezing step, and by the storage of draw ring 13 and holding tank 1221, i.e. the bottom surface of the second forming part 122
It is supported on freezing stage, ensures that draw ring 13 is not in contact with freezing stage, realize that spinal cord imbedded mold 1 is stably placed freezing stage
On effect.
The specifically used mode of spinal cord imbedded mold 1 provided in this embodiment is：
The shell of first forming part 121 is plugged in the opening of the shell of the second forming part 122, the first forming part 121
Shell and the shell of the second forming part 122 collectively form pedestal forming cavity 123.First from the opening of specimen tube 11 to mold
Inside pours into a certain amount of embedding medium, then is put into myeloid tissue from the opening of specimen tube 11, since the embedding medium first poured into has
Certain supporting role can ensure bottom surface of the myeloid tissue due to acting on and falling on spinal cord imbedded mold 1 in itself, then
Pour into embedding medium from the opening of specimen tube 11, the inner cavity 111 of the full specimen tube of the secondary embedding medium filling poured into 11 and pedestal at
Cavity 123, it is by the secondary embedding medium poured into that myeloid tissue is fully wrapped around；By the spinal cord imbedded mold 1 after filling embedding medium
It is placed on freezing stage freezing, the sample of myeloid tissue is shaped in myeloid tissue and the embedding medium of mould inside；Again by the first molding
Portion 121 is split with the second forming part 122, and sample is taken out from the opening of the larger pedestal forming cavity 123 in cross section.
Illustratively, the embedding medium that the present embodiment uses can be paraffin, gelatin, OCT (optimal cutting
The water soluble mixt of temperature compound, polyethylene glycol and polyvinyl alcohol) etc..Wherein, OCT can be to freeze
The myeloid tissue of slice plays a supporting role, and improves the continuity of myeloid tissue, and reduces fold and the fragmentation of myeloid tissue.
Embodiment two
The sectional view for the spinal cord imbedded mold that Fig. 6 embodiments two provide, as shown in fig. 6, present embodiments providing a kind of ridge
Marrow imbedded mold 1, for simplicity, only description with embodiment one the difference is that：First forming part 121 is with opening
Shell, the second forming part 122 is mounting plate, and mounting plate is plugged in the opening of shell, passes through mounting plate and shell is coordinated to constitute
Pedestal forming cavity 123 specifically, the interior shape of shell and size are adapted with the shape of mounting plate and size, and then obtains
The preferable pedestal forming cavity 123 of sealing effect is obtained, avoids the embedding medium for the inside for pouring into mold from leaking outside, reduces the wave of embedding medium
Take, improves the utilization rate of embedding medium.In addition, in another embodiment, the first forming part 121 is mounting plate, the second forming part
122 be the shell with opening, can realize said effect.
Fig. 7 is the structural schematic diagram for the first forming part that embodiment two provides, and Fig. 8 is in Fig. 7 along the section view in the directions B-B
Figure.In the present embodiment, as shown in Figure 6 to 8, the side wall of shell is inwardly provided with position limiting structure 1211, as shown in fig. 6, peace
Loading board is abutted against with position limiting structure 1211 along the direction of grafting, ensures that mounting plate is upper in axial (i.e. horizontal direction in Fig. 6)
The accurate restriction set can solve operator when installing mounting plate, cause mounting plate not determine precisely due to exerting a force inconsistent
The problem of position.Specifically, as shown in figure 8, the height of position limiting structure 1211 is identical as the height of pedestal forming cavity 123, from
The pedestal that one forming part 121 molds can smoothly take out from the first forming part 121.
As shown in fig. 7, in the present embodiment, circumferentially spaced set has opposite two to the side wall of the first forming part 121
A position limiting structure 1211 can increase the contact area of position limiting structure 1211 and mounting plate, and both direction is realized to mounting plate
It abuts so that mounting plate obtains more balanced support.Certainly, in other embodiments, the side wall of the first forming part 121 can be with
It is that circumferentially spaced set has multiple position limiting structures 1211, the quantity of position limiting structure 1211 is more, is imitated to the support of mounting plate
Fruit is better.In order to obtain maximum contact area, in other embodiments, the cross-sectional area of position limiting structure 1211 can be annulus
One circle of shape, i.e. side wall is both provided with position limiting structure 1211.But the cross-sectional area of position limiting structure 1211 is bigger, the bottom molded
The cross-sectional area of seat is smaller, can be in side wall in order to meet simultaneously to mounting plate support effect and pedestal to sample support effect
On be equidistantly provided with four position limiting structures 1211.In the present embodiment, mounting plate is circumferentially interference fitted with shell, is obtained close
The preferable pedestal forming cavity 123 of effect is sealed, avoids the embedding medium for the inside for pouring into mold from leaking outside, reduces the waste of embedding medium, carry
The utilization rate of high embedding medium.
Note that have been shown and described above the utility model basic principles and main features and the utility model it is excellent
Point.It should be understood by those skilled in the art that the utility model is not limited to the embodiments described above, the above embodiment and say
Only illustrate the principles of the present invention described in bright book, on the premise of not departing from the spirit and scope of the utility model, this
Utility model will also have various changes and improvements, and these various changes and improvements fall within the scope of the claimed invention,
The claimed range of the utility model is defined by the appending claims and its equivalent thereof.
Claims (10)
1. a kind of spinal cord imbedded mold, including specimen tube (11), which is characterized in that one end of the specimen tube (11) is provided with bottom
Seat shaping mechanism (12), the pedestal shaping mechanism (12) includes the first forming part (121) and the second forming part (122), described
First forming part (121) and second forming part (122) dismantling connection and can collectively form pedestal forming cavity (123), described
Pedestal forming cavity (123) is connected with the inner cavity (111) of the specimen tube (11), and the cross-sectional area of the inner cavity (111) is less than
The cross-sectional area of the pedestal forming cavity (123).
2. spinal cord imbedded mold according to claim 1, which is characterized in that first forming part (121) and described the
Two forming parts (122) are the shell with opening, one of them described shell is arranged in the opening of another shell.
3. spinal cord imbedded mold according to claim 1, which is characterized in that first forming part (121) and described
One in two forming parts (122) is the shell with opening, another is mounting plate, and the mounting plate is arranged in the shell
Opening in.
4. spinal cord imbedded mold according to claim 3, which is characterized in that the side wall of the shell is inwardly provided with limit
Structure (1211), the mounting plate are abutted against with the position limiting structure (1211), the height of the position limiting structure (1211) and institute
The height for stating pedestal forming cavity (123) is identical.
5. spinal cord imbedded mold according to claim 4, which is characterized in that the side wall circumferentially spaced set have it is more
A position limiting structure (1211).
6. spinal cord imbedded mold according to claim 3, which is characterized in that the mounting plate is matched with the shell interference
It closes.
7. according to claim 1~6 any one of them spinal cord imbedded mold, which is characterized in that first forming part (121)
It is integrally formed with the specimen tube (11) or can dismantling connection；Or,
Second forming part (122) is integrally formed with the specimen tube (11) or can dismantling connection.
8. according to claim 1~6 any one of them spinal cord imbedded mold, which is characterized in that first forming part (121)
It is connected with the specimen tube (11), second forming part (122) is rotatably connected to draw ring (13).
9. spinal cord imbedded mold according to claim 8, which is characterized in that the outer surface of second forming part (122)
Holding tank (1221) is offered, the draw ring (13) is accommodated in the holding tank (1221).
10. according to claim 1~6 any one of them spinal cord imbedded mold, which is characterized in that the specimen tube (11) and institute
Pedestal shaping mechanism (12) is stated to be made of acrylic plastics, polypropylene and/or silica gel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721800287.1U CN207610910U (en) | 2017-12-21 | 2017-12-21 | A kind of spinal cord imbedded mold |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721800287.1U CN207610910U (en) | 2017-12-21 | 2017-12-21 | A kind of spinal cord imbedded mold |
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| Publication Number | Publication Date |
|---|---|
| CN207610910U true CN207610910U (en) | 2018-07-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201721800287.1U Active CN207610910U (en) | 2017-12-21 | 2017-12-21 | A kind of spinal cord imbedded mold |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109946144A (en) * | 2017-12-21 | 2019-06-28 | 中国科学院深圳先进技术研究院 | A kind of spinal cord imbedded mold |
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2017
- 2017-12-21 CN CN201721800287.1U patent/CN207610910U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109946144A (en) * | 2017-12-21 | 2019-06-28 | 中国科学院深圳先进技术研究院 | A kind of spinal cord imbedded mold |
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