CN207385203U - Albumen automatic ration enrichment facility - Google Patents

Albumen automatic ration enrichment facility Download PDF

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Publication number
CN207385203U
CN207385203U CN201721367824.8U CN201721367824U CN207385203U CN 207385203 U CN207385203 U CN 207385203U CN 201721367824 U CN201721367824 U CN 201721367824U CN 207385203 U CN207385203 U CN 207385203U
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China
Prior art keywords
liquid
hollow fiber
peristaltic pump
storing barrel
albumen
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CN201721367824.8U
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Chinese (zh)
Inventor
周雷鸣
周伟伟
孙静静
程雷显
赵巧辉
李桂林
付光宇
吴学炜
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Zhengzhou Immuno Biotech Co Ltd
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Zhengzhou Immuno Biotech Co Ltd
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Priority to CN201721367824.8U priority Critical patent/CN207385203U/en
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Abstract

The utility model discloses a kind of albumen automatic ration enrichment facilities, liquid storing barrel including being provided with level electrode, the outlet tube of the liquid storing barrel is connected after peristaltic pump with hollow fiber column bottom liquid inlet mouth, the doughnut column top concentrate pipe is connected with liquid storing barrel inlet, hollow fiber column top sewer pipe is connected with waste liquid barrel, the signal output part of the level electrode is connected with controller signals input terminal, and the controller control output end is connected with the control signal of the peristaltic pump.The utility model is simple in structure, it is easy to use, maintenance cost is relatively low, it uses hollow fiber column to be filtered required albumen, using the concentration volume of level electrode control harvest liquid, and pass through the start-stop that controller automatically controls peristaltic pump, manual operation error can be reduced, worker's amount of labour is reduced, greatly improves the precision and efficiency of protein concentration.

Description

Albumen automatic ration enrichment facility
Technical field
It is automatic more particularly, to a kind of albumen the utility model is related to biology, the relevant technical field of experiment equipment of medicine Quantitative enrichment facility.
Background technology
The problem of protein concentration is frequently encountered in biological experiment, such as receipts during progress cells in vitro large-scale culture The concentration of liquid is obtained, since required antibody is dissolved into harvest liquid and antibody concentration is not high, causes harvest liquid volume larger, if It directly stores, more manpower is not only needed to be carried, it is also necessary to occupy more freezer memory space, be brought not to production Necessary trouble, therefore stored after usually harvest liquid is concentrated.However, artificial participant is taken in existing harvest liquid concentration Formula spends the time long, time-consuming and laborious, and cycles of concentration is inaccurate, influences the progress of subsequent experimental.
The content of the invention
The utility model provides a kind of albumen automatic ration enrichment facility, it is therefore intended that when solving manually to carry out protein concentration Not the problem of time-consuming and laborious and concentration precision is not good enough.
To achieve the above object, the utility model can take following technical proposals:
Albumen automatic ration enrichment facility described in the utility model, the liquid storing barrel including being provided with level electrode are described The outlet tube of liquid storing barrel is connected after peristaltic pump with hollow fiber column bottom liquid inlet mouth, doughnut column top concentrate Pipe is connected with liquid storing barrel inlet, and hollow fiber column top sewer pipe is connected with waste liquid barrel, the signal of the level electrode Output terminal is connected with controller signals input terminal, the controller control output end and the control signal phase of the peristaltic pump Connection.
Albumen automatic ration enrichment facility provided by the utility model, simple in structure, easy to use, maintenance cost is relatively low, It uses hollow fiber column to be filtered required albumen, using the concentration volume of level electrode control harvest liquid, and passes through control Device processed automatically controls the start-stop of peristaltic pump, can reduce manual operation error, reduces worker's amount of labour, greatly improves protein concentration Precision and efficiency.
Description of the drawings
Fig. 1 is the structure diagram of the utility model.
Specific embodiment
As shown in Figure 1, albumen automatic ration enrichment facility described in the utility model, including being equipped with level electrode 1(I.e. Electrode-type liquid-level meter)Liquid storing barrel 2, the outlet tube 3 of liquid storing barrel 2 connect after peristaltic pump 4 with 5 bottom liquid inlet mouth phase of hollow fiber column Connection, 5 top concentration liquid pipe 6 of hollow fiber column are connected with 2 inlet of liquid storing barrel, and 5 top sewer pipe 7 of hollow fiber column is with giving up Liquid bucket 8 is connected.Low concentration albumen harvest liquid in liquid storing barrel 2, which is evacuated to by peristaltic pump 4 in hollow fiber column 5, carries out albumen section It stays, the high concentration albumen harvest liquid after concentration is back to liquid storing barrel 2 by concentrating liquid pipe 6, and hollow fiber column 5 is from low concentration albumen Isolated waste liquid is collected through sewer pipe 7 to waste liquid barrel 8 in harvest liquid.Above-mentioned hollow fiber column 5 generally selects Shi Bichun producers The mPES material products of the 30kD of S04-E030-10 models.In order to accurately control protein concentration precision, by the letter of level electrode 1 Number output terminal is connected with 9 signal input part of controller, and 9 control output end of controller is connected with the control signal of peristaltic pump 4 It connects.After albumen harvest liquid volume concentration to desired value in liquid storing barrel 2, controller 9 receives signal and simultaneously peristaltic pump 4 is controlled to stop Operating, so as to accurately control the precision of protein concentration.In addition, peristaltic pump 4 can set what regulatory protein concentrated by rotating speed Speed, the speed are typically due to the speed manually concentrated.

Claims (1)

1. a kind of albumen automatic ration enrichment facility, it is characterised in that:Including being provided with level electrode(1)Liquid storing barrel(2), institute State liquid storing barrel(2)Outlet tube(3)Through peristaltic pump(4)Afterwards with hollow fiber column(5)Bottom liquid inlet mouth is connected, the hollow fibre Tie up column(5)Top concentrates liquid pipe(6)With liquid storing barrel(2)Inlet is connected, hollow fiber column(5)Top sewer pipe(7)With giving up Liquid bucket(8)It is connected, the level electrode(1)Signal output part and controller(9)Signal input part is connected, the control Device(9)Control output end and the peristaltic pump(4)Control signal be connected.
CN201721367824.8U 2017-10-23 2017-10-23 Albumen automatic ration enrichment facility Active CN207385203U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201721367824.8U CN207385203U (en) 2017-10-23 2017-10-23 Albumen automatic ration enrichment facility

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201721367824.8U CN207385203U (en) 2017-10-23 2017-10-23 Albumen automatic ration enrichment facility

Publications (1)

Publication Number Publication Date
CN207385203U true CN207385203U (en) 2018-05-22

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201721367824.8U Active CN207385203U (en) 2017-10-23 2017-10-23 Albumen automatic ration enrichment facility

Country Status (1)

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CN (1) CN207385203U (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111318077A (en) * 2018-12-13 2020-06-23 中国科学院青岛生物能源与过程研究所 Multiplex convection chromatographic system and method for purifying protein by using same
CN111592985A (en) * 2020-04-28 2020-08-28 郑州伊美诺生物技术有限公司 Continuous culture device and culture method for hybridoma cells

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111318077A (en) * 2018-12-13 2020-06-23 中国科学院青岛生物能源与过程研究所 Multiplex convection chromatographic system and method for purifying protein by using same
CN111592985A (en) * 2020-04-28 2020-08-28 郑州伊美诺生物技术有限公司 Continuous culture device and culture method for hybridoma cells
CN111592985B (en) * 2020-04-28 2024-02-06 郑州伊美诺生物技术有限公司 Continuous culture device and method for hybridoma cells

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