CN207259418U - A kind of production system - Google Patents

Abstract

Field of chemical equipment is the utility model is related to, more particularly to a kind of production system.The utility model provides a kind of production system, including reaction unit, water phase storage device, enrichment facility, the first condensing unit, liquid phase retracting device, thin film evaporation unit, liquid phase reception device, the second condensing unit, crystallization apparatus, equipment for separating liquid from solid.Production system provided by the utility model is directed to and utilizes benzylamine, glutaraldehyde, 1, 3 acetone dicarboxylic acids and aquatic production 9 benzyl, 9 azabicyclo [3.3.1] nonane, 3 ketone are specifically designed, design structure is reasonable, can be directly, effectively 9 benzyl, 9 azabicyclo [3.3.1] nonane, 3 ketone crude product is purified, using thin film evaporation can be rapidly and efficiently by product and tar separation, production efficiency is high, avoid product is heated for a long time from causing decomposed metamorphic, energy high efficiency extraction goes out high purity product, and energy consumption is small, cost is low, mass produced especially suitable for industrialization.

Description

A kind of production system

Technical field

Field of chemical equipment is the utility model is related to, more particularly to a kind of production system, being more particularly to one kind can use In the production system of the purification process of industrialized production 9- benzyl -9- azabicyclos [3.3.1] nonane -3- ketone.

Background technology

9- benzyl -9- azabicyclos [3.3.1] nonane -3- ketone is a kind of important pharmaceutical intermediate, its main application bag Include the medicine for preparing and being used for treating or preventing depression, anxiety disorder, pain, panic disorder and obsession.Document Bioorganic＆ Medicinal Chemistry,23(7),1463-1471；2015 are reported and are existed with benzylamine, glutaraldehyde and 1,3- acetone dicarboxylic acid The method of reaction synthesis 9- benzyl -9- azabicyclos [3.3.1] nonane -3- ketone in aqueous solution.But the current product is at home The starting stage is in outside, the device and system separated to its crude product, purified are rarely reported.Existing chemical system does not have Specifically for the design of 9- benzyl -9- azabicyclos [3.3.1] nonane -3- ketone purification systems, the industry of the product certainly will be influenced Change process and production efficiency.Since 9- benzyl -9- azabicyclos [3.3.1] nonane -3- ketone product heat endurances are bad and only Special chemical property, it is conventional isolate and purify systemic effect when the product there are it is many problem of：Such as using recrystallization point From system, the tar produced in product preparation process can not be effectively removed, recrystallization product external standard content only has 93%, can not Meet the quality standard of medicine intermediate；And tar removing also can not effectively be gone using activated carbon adsorption, and decolorizing effect is also unknown It is aobvious；Column chromatography system production efficiency is low, and manufacturing cost is high；Conventional distil-lation system, due to needing long-time heating, product is easily sent out Raw oxygenolysis, influences product quality and yield.As it can be seen that the industrialization of 9- benzyl -9- azabicyclos [3.3.1] nonane -3- ketone Production has high requirement, it is necessary to develop the equipment that matches with technique to carry out 9- benzyl -9- azepines for purification system Bicyclic [3.3.1] nonane -3- ketone isolates and purifies.

Utility model content

In view of the foregoing deficiencies of prior art, the purpose of this utility model is to provide a kind of production system, it is used for Solve the problems of the prior art.

In order to achieve the above objects and other related objects, the utility model provides a kind of production system, including：

The reaction unit reacted for reaction raw materials；

For the water phase storage device of reaction gained aqueous phase substance in storage reaction device, the water phase storage device with it is anti- Device is answered to be in fluid communication；

For will in reaction unit reaction gained oil phase substance carry out concentration enrichment facility, the enrichment facility with Reaction unit is in fluid communication；

For gas phase stream stock obtained by concentration to carry out to the first condensing unit of condensation process, the condensing unit with it is dense Compression apparatus is in fluid communication；

For storing the liquid phase retracting device of liquid phase stream stock obtained by condensation process in the first condensing unit, the liquid phase recycling Device and the first condensing unit are in fluid communication；

For liquid phase stream stock obtained by concentration to be carried out to the thin film evaporation unit of thin film evaporation processing, the thin film evaporation Device is in fluid communication with enrichment facility；

For the liquid phase reception device of liquid phase stream stock obtained by memory films evaporation process, the liquid phase reception device and film Vaporising device is in fluid communication；

For thin film evaporation processing gained gas phase stream stock to be carried out to the second condensing unit of condensation process, second condensation Device is in fluid communication with thin film evaporation unit；

For liquid phase stream stock obtained by condensation process in the second condensing unit to be carried out to the crystallization apparatus of crystallization treatment, the knot Brilliant device and the second condensing unit are in fluid communication；

For crystallization treatment products therefrom to be carried out to the equipment for separating liquid from solid of solid-liquid separation treatment, the equipment for separating liquid from solid It is in fluid communication with crystallization apparatus.

In the utility model some embodiments, the reaction unit includes reaction kettle body, the reaction kettle body It is equipped with first heater and the first agitating device.

In the utility model some embodiments, the connecting pipeline of reaction unit and water the phase storage device is equipped with First flow regulating device, the connecting pipeline of the reaction unit and enrichment facility are equipped with second flow regulating device.

In the utility model some embodiments, the connecting pipeline of first condensing unit and enrichment facility is equipped with 3rd flow regulator.

In the utility model some embodiments, further include cold for gas phase stream stock obtained by concentration to be introduced first First vacuum extractor of solidifying device, first vacuum extractor and the first condensing unit are in fluid communication.

In the utility model some embodiments, the enrichment facility includes concentration kettle body, the concentration kettle body It is equipped with secondary heating mechanism and the second agitating device.

In the utility model some embodiments, the connecting pipeline of the thin film evaporation unit and enrichment facility is equipped with 4th flow regulator 61.

In the utility model some embodiments, further include for thin film evaporation processing gained gas phase stream stock to be introduced the Second vacuum extractor of two condensing units, second vacuum extractor and the second condensing unit are in fluid communication.

, the crystallization apparatus includes crystallization kettle body, and the crystallization kettle body is stirred equipped with the 3rd heating unit and the 3rd Mix device.

In the utility model some embodiments, the connecting pipe of the crystallization apparatus and equipment for separating liquid from solid is equipped with 5th flow regulator.

Brief description of the drawings

Fig. 1 is shown as the utility model structure diagram.

Component label instructions

1 reaction unit

11 reaction kettle bodies

12 first heaters

13 first agitating devices

2 water phase storage devices

21 first flow regulating devices

22 water phase storage devices introduce pipeline

3 enrichment facilities

31 second flow regulating devices

32 the 3rd flow regulators

33 concentration kettle bodies

34 secondary heating mechanisms

35 second agitating devices

36 enrichment facilities introduce pipeline

37 enrichment facility gas phase stream stock introduction pipes

4 first condensing units

41 first vacuum extractors

42 first condensing unit introduction pipes

5 liquid phase retracting devices

51 liquid phase retracting devices introduce pipeline

6 thin film evaporation units

61 the 4th flow regulators

62 thin film evaporation units introduce pipeline

63 thin film evaporation unit gas phase stream stock introduction pipes

7 second condensing units

71 second vacuum extractors

72 second condensing unit introduction pipes

8 liquid phase reception devices

81 liquid phase reception devices introduce pipeline

9 crystallization apparatus

91 crystallization kettle bodies

92 the 3rd heating units

93 the 3rd agitating devices

94 the 5th flow regulators

95 crystallization apparatus introduce pipeline

96 crystallization apparatus introduction pipes

10 equipment for separating liquid from solid

Embodiment

Illustrate the embodiment of the utility model by particular specific embodiment below, those skilled in the art can be by this Content disclosed by specification understands other advantages and effect of the utility model easily.

Please refer to Fig.1.It should be clear that structure, ratio, size depicted in this specification institute accompanying drawings etc., only coordinating The revealed content of specification, so that those skilled in the art understands and reads, being not limited to the utility model can be real The qualifications applied, therefore do not have technical essential meaning, the tune of the modification of any structure, the change of proportionate relationship or size It is whole, in the case where not influencing the effect of the utility model can be generated and the purpose that can reach, should all still fall in the utility model institute The technology contents of announcement are obtained in the range of covering.Meanwhile in this specification it is cited as " on ", " under ", "left", "right", The term of " centre " and " one " etc., is merely convenient to understanding for narration, and is not used to limit the enforceable scope of the utility model, Its relativeness is altered or modified, in the case where changing technology contents without essence, when being also considered as the enforceable category of the utility model.

As shown in Figure 1, the utility model provides a kind of production system, including reaction unit 1, water phase storage device 2, concentration Device 3, the first condensing unit 4, liquid phase retracting device 5, thin film evaporation unit 6, the second condensing unit 7, liquid phase reception device 8, Crystallization apparatus 9 and equipment for separating liquid from solid 10.

It can include reaction unit 1 in production system provided by the utility model, the reaction unit 1 can be for reaction Raw material is reacted, for example, it may be preparing 9- benzyl -9- azabicyclos with benzylamine, glutaraldehyde, 1,3- acetone dicarboxylic acids and water The reaction of [3.3.1] nonane -3- ketone, the chemical equation involved by above-mentioned reaction are as follows：

The reaction unit 1 can usually include reaction kettle body 11, so as to be carried out in reaction kettle body 11 Reaction is stated, the reaction kettle body 11 can be such as autoclave body and/or tank body.The can be equipped with the reaction kettle body 11 One heating unit 12, so as to be heated to the material in reaction kettle body 11, the first heater 12 can be Such as it can be such as electrical heating, steam suitable for heating mantle of reaction kettle and/or retort etc., the mode of heating of the heating mantle Vapour heating etc..The first agitating device 13 is also provided with the reaction kettle body 11, so as to in reaction kettle body 11 Material be stirred, be sufficiently mixed reaction raw materials, so as to lift reaction efficiency, first agitating device 13 can be this The various blenders suitable for reaction kettle in field.

It can also include water phase storage device 2, the water phase storage device 2 in production system provided by the utility model It can be in fluid communication with reaction unit 1, pipeline 22 can be more specifically introduced by water phase storage device and is connected with 1 fluid of reaction unit Logical, the water phase storage device 2 can be used in storage reaction device 1 reacting gained aqueous phase substance (for example, in aqueous phase substance absolutely Major part can be water, can also contain the raw material reacted on a small quantity), in reaction unit 1 after the completion of reaction, products therefrom would generally divide Layer forms water phase and oil phase, aqueous phase substance and can be introduced into water phase storage device 2, in order to further carry out subsequent treatment (for example, can be introduced back in next batch reaction in reaction unit 1, set is used for next group and reacts), the water phase storage device 2 Can be autoclave body and/or tank body etc..It is typically provided with the connecting pipeline of the reaction unit 1 and water phase storage device 2 first-class Quantity regulating device 21, the first flow regulating device 21 can be opened and closed, adjust the flow of fluid in connecting pipeline, so as to Proper amount of aqueous phase substance autoreaction device 1 is introduced into water phase storage device 2 when needed, the first flow regulating device 21 can be such as valve.

Can also include enrichment facility 3 in production system provided by the utility model, the enrichment facility 3 can with it is anti- Device 1 is answered to be in fluid communication, more specifically can introduce pipeline 36 by enrichment facility is in fluid communication with reaction unit 1, the concentration Device 3 can be used for reaction gained oil phase substance in reaction unit 1 (for example, reaction gained oil phase substance in reaction unit 1 Can be the accessory substances such as reaction dissolvent, product and tar) concentration is carried out, the concentration is often referred to steam by solvent Send out and improve the processing method of the concentration of solution, reaction gained oil phase substance can be introduced into enrichment facility 3 in reaction unit 1 Concentration is subjected to, so as to form gas phase stream stock obtained by concentration (for example, the mainly solvent containing a small amount of azeotropic water is formed Gas phase stream stock) and concentration obtained by liquid phase stream stock (for example, liquid phase stream stock obtained by concentration can mainly contain product, The accessory substances such as tar, can also contain the solvent no more than 5%).The enrichment facility can usually include concentration kettle body 33, So as to which reaction gained oil phase substance in reaction unit 1 is introduced into concentration kettle body 33 and further carries out concentration, The reaction kettle body 11 can be such as autoclave body and/or tank body.The concentration kettle body 33 is equipped with secondary heating mechanism 34, so as to be heated to the material in concentration kettle body 33, the secondary heating mechanism 34 can be such as heating mantle Mode of heating Deng, the heating mantle can be such as electrical heating, steam heating.It can also be set on the concentration kettle body 33 There is the second agitating device 35, so as to be stirred to the material in concentration kettle body 33, be heated evenly material, so as to carry The effect of concentration is risen, second agitating device 35 can be the various blenders suitable for reaction kettle in this area.It is described Second flow regulating device 31, the second flow tune can be usually equipped with the connecting pipeline of reaction unit 1 and enrichment facility 3 Regulating device 31 can be opened and closed, adjust the flow of fluid in connecting pipeline, so as to when needed by proper amount of oil phase substance Autoreaction device 1 is introduced into enrichment facility 3, and the second flow regulating device 31 can be such as valve.

It can also include the first condensing unit 4 in production system provided by the utility model, the condensing unit 4 can be with It is in fluid communication with enrichment facility 3, can be more specifically in fluid communication by enrichment facility introduction pipe 37 and enrichment facility 3, it is described First condensing unit 4 can be used for gas phase stream stock obtained by concentration carrying out condensation process, and the condensation process is often referred to Crossing reduces temperature so that gaseous material cooling is so as to form the processing method of liquid, concentration institute in enrichment facility 3 Gas phase stream stock can be introduced into the first condensing unit 4 and be subjected to condensation process, so as to form liquid phase stream stock obtained by condensation process Obtained by (for example, the liquid phase stream stock obtained by condensation process can be solvent and a small amount of water come out with solvent azeotropic) and condensation process Gas phase stream stock (for example, gas phase stream stock obtained by condensation process can be mainly a small amount of uncooled complete solvent), condensation process institute Production system can be brought out by obtaining gas phase stream stock.First condensing unit 4 can usually include hollow condensation column, described cold Solidifying column can be in fluid communication with enrichment facility 3, and gas phase stream stock obtained by concentration, which can be introduced into, to be introduced into condensation column, described cold Condenser can be equipped with solidifying column, will at least so as to the temperature of the gas phase stream stock as obtained by condenser reduction concentration Gas phase stream stock obtained by partial concentration liquefies to form liquid phase stream stock obtained by condensation process, and gas phase stream stock obtained by condensation process can To be brought out the first condensing unit 4 by the first condensing unit introduction pipe 42.First condensing unit 4 and enrichment facility 3 Connecting pipeline be located at the arrival end of enrichment facility 3 and be usually located at the top of enrichment facility 3, so as to easy to concentration institute Obtain gas phase stream stock and draw enrichment facility 3, can be usually equipped with the connecting pipeline of first condensing unit 4 and enrichment facility 3 3rd flow regulator 32, the 3rd flow regulator 32 can be opened and closed, adjust the flow of fluid in connecting pipeline, So as to which gas phase stream stock obtained by proper amount of concentration is introduced into the first condensing unit 4 from enrichment facility 3 when needed, 3rd flow regulator 32 can be such as valve.It can also include being used to draw gas phase stream stock obtained by concentration Enter the first vacuum extractor 41 of the first condensing unit 4,41 and first condensing unit of the first vacuum extractor, 4 fluid connects It is logical, it can be more specifically in fluid communication by condensing unit introduction pipe 42 and the first condensing unit 4, so as to cold by first While gas is drawn in solidifying device 4, negative pressure is formed in the first condensing unit 4, makes gas phase stream stock obtained by concentration can be with It is introduced into the first condensing unit 4, first vacuum extractor 41 can be such as air pump.

It can also include liquid phase retracting device 5, the liquid phase retracting device 5 in production system provided by the utility model It can be in fluid communication with the first condensing unit 4, the condensation dress of pipeline 51 and first can be more specifically introduced by liquid phase retracting device 4 fluid communication are put, the liquid phase retracting device 5 can be used for storing liquid phase stream stock obtained by condensation process in the first condensing unit 4. Liquid phase stream stock obtained by condensation process can be introduced into liquid phase retracting device 5 in first condensing unit 4, in order to further carry out Subsequent treatment (for example, can be introduced back in next batch reaction in reaction unit 1, set is used for next group and reacts), the liquid phase Retracting device 5 can be autoclave body and/or tank body etc..The connecting pipe of the liquid phase retracting device 5 and the first condensing unit 4 is located at Entrance in first condensing unit 4 is usually located at the bottom of the first condensing unit 4, so as to will be cold by gravity Solidifying processing gained liquid phase stream stock is drawn from the first condensing unit 4, and the level height of the liquid phase retracting device 5 is usually less than the One condensing unit 4, so as to as gravity by condensation process obtained by liquid phase stream stock be introduced into liquid phase retracting device 5.

It can also include thin film evaporation unit 6, the thin film evaporation unit 6 in production system provided by the utility model It can be in fluid communication with enrichment facility 3, pipeline 62 can be more specifically introduced by thin film evaporation unit and is connected with 3 fluid of enrichment facility Logical, the thin film evaporation unit 6 can be used for liquid phase stream stock obtained by concentration carrying out thin film evaporation processing, the film evaporation Processing is often referred to the processing that liquid material is conducted heat and evaporated in membranaceous flowing along heating tube wall using thin film evaporator Method, liquid phase stream stock obtained by concentration, which can be introduced into thin film evaporation unit 6, is subjected to film evaporation process, so as to form film Gas phase stream stock obtained by evaporation process (for example, thin film evaporation processing gained gas phase stream stock can be mainly product and a small amount of impurity) and (thin film evaporation processing gained liquid phase stream stock is usually the higher material of some boiling points to thin film evaporation processing gained liquid phase stream stock, example Such as, can be the height boiling such as tar accessory substance), the thin film evaporation unit 6 usually can be thin film evaporator etc., art technology Personnel according to reaction condition, can select the thin film evaporator of suitable parameters and select suitable reaction condition, for example, the film The inlet amount of evaporator can be 20-100Kg/h, and evaporation capacity can be 40-80Kg/h, heating-up temperature can reach 200 DEG C with On, evaporite ratio (concentration/charging) can be 1：5-150.Set on the connecting pipeline of the thin film evaporation unit 6 and enrichment facility 3 There is the 4th flow regulator 61, the 4th flow regulator 61 can be opened and closed, adjust the flow of fluid in connecting pipeline, So as to which liquid phase stream stock obtained by proper amount of concentration is introduced into thin film evaporation unit 6 from enrichment facility 3 when needed, 4th flow regulator 61 can be such as valve.

It can also include liquid phase reception device 8, the liquid phase reception device 8 in production system provided by the utility model It can be in fluid communication with thin film evaporation unit 6, pipeline 81 can be more specifically introduced by liquid phase reception device and is filled with thin film evaporation 6 fluid communication (being usually connected with the liquid-phase outlet of thin film evaporation unit 6) are put, the liquid phase reception device 8 can be used for storing Thin film evaporation processing gained liquid phase stream stock.The liquid phase stream stock of thin film evaporation processing gained can be introduced into thin film evaporation unit 6 In liquid phase reception device 8, in order to further carry out subsequent treatment, the liquid phase reception device 8 can be autoclave body and/or tank body Deng.The connecting pipe of the liquid phase reception device 8 and thin film evaporation unit 6 is located at the entrance in thin film evaporation unit 6 and leads to Be frequently located in the bottom of thin film evaporation unit 6, so as to as gravity by thin film evaporation processing obtained by liquid phase stream stock from To be drawn in thin film evaporation unit 5, the level height of the liquid phase reception device 8 is usually less than thin film evaporation unit 6, so as to Liquid phase stream stock as obtained by gravity by thin film evaporation processing is introduced into liquid phase reception device 8.

It can also include the second condensing unit 7, second condensing unit 7 in production system provided by the utility model Can be in fluid communication with thin film evaporation unit 6, more specifically can by thin film evaporation unit gas phase stream stock introduction pipe 63 with it is thin Film evaporator 6 is in fluid communication and (is usually connected with the gaseous phase outlet of thin film evaporation unit 6), and second condensing unit 7 can be with For thin film evaporation processing gained gas phase stream stock to be carried out condensation process, thin film evaporation handles gained in thin film evaporation unit 6 Gas phase stream stock can be introduced into the second condensing unit 7 and be subjected to condensation process, so as to form liquid phase stream stock (example obtained by condensation process Such as, liquid phase stream stock obtained by condensation process can be product and a small amount of impurity) and condensation process obtained by gas phase stream stock (for example, condensing Processing gained gas phase stream stock can be the uncooled organic volatile of very small amount), gas phase stream stock obtained by condensation process can be drawn Go out production system.Second condensing unit 7 can usually include hollow condensation column, and the condensation column can be with thin film evaporation Device 6 is in fluid communication, and thin film evaporation processing gained gas phase stream stock can be introduced into condensation column, can be equipped with the condensation column Condenser, so as to the temperature of the gas phase stream stock as obtained by condenser reduction thin film evaporation processing, by least part of concentration Processing gained gas phase stream stock liquefies to form liquid phase stream stock obtained by condensation process, and gas phase stream stock obtained by condensation process can pass through second Condensing unit introduction pipe 72 is brought out the second condensing unit 7.It can also include being used for thin film evaporation processing gained gas phase stream Stock introduces the second vacuum extractor 71 of the second condensing unit 7,71 and second condensing unit of the second vacuum extractor, 7 fluid Connection, can be more specifically in fluid communication by the second condensing unit introduction pipe 72 and the second condensing unit 7, so as to incite somebody to action While gas is drawn in second condensing unit 7, negative pressure is formed in the second condensing unit 7, thin film evaporation processing is brought about the desired sensation Mutually stream stock can be introduced into the second condensing unit 7, and second vacuum extractor 71 can be such as air pump.

It can also include crystallization apparatus 9 in production system provided by the utility model, the crystallization apparatus 9 can be with Two condensing units 7 are in fluid communication, and more specifically can introduce pipeline 95 by crystallization apparatus is in fluid communication with the second condensing unit 7, The crystallization apparatus 9 is used to liquid phase stream stock obtained by condensation process in the second condensing unit 7 carrying out crystallization treatment, at the crystallization Reason is often referred to the processing method that separates out solute in the form of crystal, the condensation process gained liquid phase stream in the second condensing unit 7 Stock, which can be introduced into crystallization apparatus 9, is subjected to crystallization treatment, so as to form crystal (main component of crystal is target product). The crystallization apparatus 9 can usually include crystallization kettle body 91, so as to by liquid obtained by condensation process in the second condensing unit 7 Mutually stream stock is introduced into crystallization kettle body 91 and further carries out crystallization treatment, and the crystallization kettle body 91 can be such as autoclave body And/or tank body etc..The crystallization kettle body 91 is equipped with the 3rd heating unit 92, so as to the thing in crystallization kettle body 91 Material is heated, and the 3rd heating unit 92 can be such as heating mantle, and the mode of heating of the heating mantle can be example Such as electrical heating, steam are heated.The 3rd agitating device 93 is also provided with the crystallization kettle body 91, so as to crystallization Material in kettle body 91 is stirred, so as to lift the effect of crystallization treatment, the 3rd agitating device 93 can be ability The various blenders suitable for reaction kettle in domain.

It can also include equipment for separating liquid from solid 10, the equipment for separating liquid from solid in production system provided by the utility model 10 can be in fluid communication with crystallization apparatus 9, can more specifically be connected by crystallization apparatus introduction pipe 96 and 9 fluid of crystallization apparatus Logical, the equipment for separating liquid from solid 10 can be used for crystallization treatment products therefrom carrying out solid-liquid separation treatment, the separation of solid and liquid Processing is often referred to solidliquid mixture carrying out separated processing method, and crystallization treatment products therefrom can be introduced into separation of solid and liquid dress Solid-liquid separation treatment is subjected in putting 10, so that by crystalline product and liquid phase separation, the equipment for separating liquid from solid 10 can be centrifugation Machine etc..The 5th flow regulator 94 is typically provided with the connecting pipeline of the equipment for separating liquid from solid 10 and crystallization apparatus 9, it is described 5th flow regulator 94 can be opened and closed, adjust the flow that stock is flowed in connecting pipeline, so as to when needed by appropriate amount Crystallization treatment after product be introduced into from crystallization apparatus 9 in equipment for separating liquid from solid 10, the 5th flow regulator 94 can be with It is such as valve.The equipment for separating liquid from solid 10 can be located at the pipeline in crystallization apparatus 9 with the connecting pipe of crystallization apparatus 9 Entrance is usually located at the bottom of crystallization apparatus 9, so as to by gravity by crystallization treatment products therefrom from crystallization apparatus 9 Middle extraction, the level height of the equipment for separating liquid from solid 10 are usually less than crystallization apparatus 9, so as to be tied by gravity Crystalline substance processing products therefrom is introduced into equipment for separating liquid from solid 10.

Production system provided by the utility model is directed to and utilizes benzylamine, glutaraldehyde, 1,3- acetone dicarboxylic acids and aquatic production 9- Benzyl -9- azabicyclos [3.3.1] nonane -3- ketone is specifically designed, and design structure is reasonable, can be directly and efficiently to 9- benzyls Base -9- azabicyclos [3.3.1] nonane -3- ketone crude products are purified, using thin film evaporation can be rapidly and efficiently by product with it is burnt Oily separation, production efficiency is high, avoids product is heated for a long time from causing decomposed metamorphic, and energy high efficiency extraction goes out high purity product, and Energy consumption is small, cost is low, is mass produced especially suitable for industrialization.

In conclusion the utility model effectively overcomes various shortcoming of the prior art and has high industrial exploitation value Value.

The above embodiments are only illustrative of the principle and efficacy of the utility model, new not for this practicality is limited Type.Any person skilled in the art can all carry out above-described embodiment under the spirit and scope without prejudice to the utility model Modifications and changes.Therefore, such as those of ordinary skill in the art without departing from the revealed essence of the utility model God and all equivalent modifications completed under technological thought or change, should be covered by the claim of the utility model.

Claims (10)

1. A kind of 1. production system, it is characterised in that including

   The reaction unit (1) reacted for reaction raw materials；

   For the water phase storage device (2) of reaction gained aqueous phase substance in storage reaction device (1), the water phase storage device (2) it is in fluid communication with reaction unit (1)；

   For reaction gained oil phase substance in reaction unit (1) to be carried out to the enrichment facility (3) of concentration, the enrichment facility (3) it is in fluid communication with reaction unit (1)；

   For gas phase stream stock obtained by concentration to carry out to the first condensing unit (4) of condensation process, the condensing unit (4) with Enrichment facility (3) is in fluid communication；

   For storing the liquid phase retracting device (5) of liquid phase stream stock obtained by condensation process in the first condensing unit (4), the liquid phase is returned Receiving apparatus (5) is in fluid communication with the first condensing unit (4)；

   For liquid phase stream stock obtained by concentration to be carried out to the thin film evaporation unit (6) of thin film evaporation processing, the thin film evaporation Device (6) is in fluid communication with enrichment facility (3)；

   For the liquid phase reception device (8) of liquid phase stream stock obtained by memory films evaporation process, the liquid phase reception device (8) with it is thin Film evaporator (6) is in fluid communication；

   For thin film evaporation processing gained gas phase stream stock to be carried out to the second condensing unit (7) of condensation process, second condensation Device (7) is in fluid communication with thin film evaporation unit (6)；

   It is described for liquid phase stream stock obtained by condensation process in the second condensing unit (7) to be carried out to the crystallization apparatus (9) of crystallization treatment Crystallization apparatus (9) is in fluid communication with the second condensing unit (7)；

   For crystallization treatment products therefrom to be carried out to the equipment for separating liquid from solid (10) of solid-liquid separation treatment, the equipment for separating liquid from solid (10) it is in fluid communication with crystallization apparatus (9).
2. 2. production system according to claim 1, it is characterised in that the reaction unit (1) includes reaction kettle body (11), the reaction kettle body (11) is equipped with first heater (12) and the first agitating device (13).
3. 3. production system according to claim 1, it is characterised in that the reaction unit (1) and water phase storage device (2) Connecting pipeline be equipped with first flow regulating device (21), on the connecting pipeline of the reaction unit (1) and enrichment facility (3) Equipped with second flow regulating device (31).
4. 4. production system according to claim 1, it is characterised in that first condensing unit (4) and enrichment facility (3) Connecting pipeline be equipped with the 3rd flow regulator (32).
5. 5. production system according to claim 1, it is characterised in that further include and be used for gas phase stream stock obtained by concentration Introduce the first vacuum extractor (41) of the first condensing unit (4), first vacuum extractor (41) and the first condensing unit (4) it is in fluid communication.
6. 6. production system according to claim 1, it is characterised in that the enrichment facility includes concentration kettle body (33), The concentration kettle body (33) is equipped with secondary heating mechanism (34) and the second agitating device (35).
7. 7. production system according to claim 1, it is characterised in that the thin film evaporation unit (6) and enrichment facility (3) Connecting pipeline be equipped with the 4th flow regulator (61).
8. 8. production system according to claim 1, it is characterised in that further include for thin film evaporation to be handled gained gas phase Flow the second vacuum extractor (71) that stock introduces the second condensing unit (7), second vacuum extractor (71) and the second condensation Device (7) is in fluid communication.
9. 9. production system according to claim 1, it is characterised in that the crystallization apparatus (9) includes crystallization kettle body (91), the crystallization kettle body (91) is equipped with the 3rd heating unit (92) and the 3rd agitating device (93).
10. 10. production system according to claim 1, it is characterised in that the crystallization apparatus (9) and equipment for separating liquid from solid (10) connecting pipe is equipped with the 5th flow regulator (94).