CN207197881U - The device for being demulsified and separating for a small amount of vaccines - Google Patents
The device for being demulsified and separating for a small amount of vaccines Download PDFInfo
- Publication number
- CN207197881U CN207197881U CN201720958030.2U CN201720958030U CN207197881U CN 207197881 U CN207197881 U CN 207197881U CN 201720958030 U CN201720958030 U CN 201720958030U CN 207197881 U CN207197881 U CN 207197881U
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- sleeve pipe
- outer tube
- port lid
- lid
- small amount
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Abstract
The utility model provides a kind of device for being demulsified and separating for a small amount of vaccines, including outer tube and sleeve pipe, and one end of the outer tube is provided with lid, and the inside installation sleeve pipe and port lid of the outer tube, described sleeve pipe is between lid and port lid；The port lid is arranged on bottom and the sleeve pipe connection of outer tube.The present apparatus has advantages below：By increasing the inner tube containing bottom fluid hole in centrifuge tube, it is clear to preserve water-oil interface during aqueous phase discharge, and steady decline, the oil phase of aqueous top layer will not enter aqueous phase；Water-oil interface remains clear during aqueous phase is extracted, and can reclaim aqueous phase to a greater extent, saves sample；Flowmeter can be connected to screw thread fluid hole, control the velocity of discharge of liquid, sample volume is collected in accurate control；The demulsification of a small amount of vaccines is can be not only used for, can be also used for the processing detection of the industrial small amount of water oil waste liquid of vaccine.
Description
Technical field
Synthetic peptide vaccine demulsification field is the utility model is related to, in particular it relates to which a kind of be used for the demulsification of a small amount of vaccines and divide
From device.
Background technology
Aftosa synthetic peptide vaccine is by adding demulsifier, making the aqueous phase containing antigen and oil phase point in vaccine at present
From.Present vaccine demulsification is that centrifugation demulsification is carried out in centrifuge tube, and the demulsification time is short, and the water-oil interface after demulsification is clear, but
Following defect be present during aqueous phase after extraction demulsification：
First, during aqueous phase is extracted, water-oil interface is destroyed, and the part oil phase of aqueous top layer can enter aqueous phase,
Pollute aqueous phase；
Second, during aqueous phase is extracted, water-oil interface is destroyed, and is caused the aqueous phase volume of recovery to tail off, is caused sample
Product waste；
3rd, the volume that different personnel extract aqueous phase is different, and the oily impurity of introducing is different, operating difficulties.
Utility model content
For in the prior art the defects of, the purpose of this utility model, which is to provide, a kind of to be used for a small amount of vaccines and is demulsified and separates
Device.
A kind of device for being demulsified and separating for a small amount of vaccines, including outer tube and sleeve pipe, institute are provided according to the utility model
The one end for stating outer tube is provided with lid, the inside installation sleeve pipe and port lid of the outer tube, described sleeve pipe be located at lid and port lid it
Between；The port lid is arranged on bottom and the sleeve pipe connection of outer tube.
Preferably, the interior sidewall surface mirror-smooth of the outer tube, the outer side surface mirror-smooth of described sleeve pipe；Described sleeve pipe
Outer side surface be bonded with the interior sidewall surface of outer tube.
Preferably, the bottom surface of described sleeve pipe is in axial direction provided with fluid hole, and described sleeve pipe passes through fluid hole and port lid
Connection；The junction of the fluid hole and port lid is provided with pad.
Preferably, after the fluid hole is connected with port lid, the bottom surface of described sleeve pipe has between the top surface of the port lid
Gap.
Preferably, the fluid hole is connected through a screw thread with port lid, specifically, the fluid hole is provided with external thread section,
The port lid is provided with the internal thread hole section matched with the external thread section of fluid hole；
The bottom of the port lid is provided with pad, and the internal thread hole section of the fluid hole through port lid contacts with pad.
Preferably, the port lid contacts with the bottom of outer tube, and the bottom of the outer tube is in inverted round table structure, the port lid
The external diameter of internal thread hole section be more than the basal diameter of the inverted round table structure, the height of the internal thread hole section of the port lid is small
In the height of the inverted round table structure.
Preferably, the lid, fluid hole and port lid are respectively positioned on the axis of described device；
The outer tube, sleeve pipe are transparent material, and scale is provided with the tube wall of described sleeve pipe.
Preferably, after described sleeve pipe is taken out from outer tube, the fluid hole is connected by pad with flowmeter.
Preferably, the outer tube is installed with lid by screw thread, specifically, the outer tube upper end is provided with external screw thread
Section, it is provided with the internal thread segment matched with the external thread section of outer tube in the lid.
Preferably, described sleeve pipe top surface is provided with circle ring rack, and circumference of the circle ring rack along the inlet of sleeve pipe is set
Put；
The internal diameter of the circle ring rack is identical with the internal diameter of sleeve pipe, and the external diameter of the circle ring rack is not more than the outer spiral shell of outer tube
The diameter of line section.
Compared with prior art, the utility model has following beneficial effect：
1st, can during aqueous phase is discharged by increasing the inner tube containing bottom fluid hole in centrifuge tube in the present apparatus
Clear to preserve water-oil interface, steady to decline, the oil phase of aqueous top layer will not enter aqueous phase.
2nd, water-oil interface remains clear during aqueous phase is extracted in the present apparatus, can recycle-water to a greater extent
Phase, save sample.
The 3rd, flowmeter can be connected to screw thread fluid hole in the present apparatus, control the velocity of discharge of liquid, accurate control is received
Collect sample volume.
4th, the present apparatus can be not only used for the demulsification of a small amount of vaccines, can be also used for the industrial small amount of water oil waste liquid of vaccine
Processing detection.
Brief description of the drawings
By reading the detailed description made with reference to the following drawings to non-limiting example, other spies of the present utility model
Sign, objects and advantages will become more apparent upon：
Fig. 1 is structural representation of the present utility model；
Fig. 2 is the schematic diagram that sleeve pipe of the present utility model is connected with flowmeter；
In figure, lid 1, outer tube 2, sleeve pipe 3, fluid hole 4, port lid 5, circle ring rack 6, flowmeter 7.
Embodiment
The utility model is described in detail with reference to specific embodiment.Following examples will be helpful to this area
Technical staff further understands the utility model, but does not limit the utility model in any form.It should be pointed out that to ability
For the those of ordinary skill in domain, without departing from the concept of the premise utility, some changes and improvements can also be made.
These belong to the scope of protection of the utility model.
The utility model provides a kind of device for being demulsified and separating for a small amount of vaccines, as shown in figure 1, including the He of outer tube 2
Sleeve pipe 3, one end of the outer tube 2 are provided with lid 1, the inside installation sleeve pipe 3 and port lid 5 of the outer tube 2, described sleeve pipe 3
Between lid 1 and port lid 5；The bottom that the port lid 5 is arranged on outer tube 2 is connected with sleeve pipe 3.
The interior sidewall surface mirror-smooth of the outer tube 2, the outer side surface mirror-smooth of described sleeve pipe 3；Outside described sleeve pipe 3
Side wall is bonded with the interior sidewall surface of outer tube 2.It should be noted that to appear clearly from the position relationship of outer tube 2 and sleeve pipe 3,
Deliberately shown in Fig. 1 between the interior sidewall surface of the outer side surface of sleeve pipe 3 and outer tube 2 with gap.
The bottom surface of described sleeve pipe 3 is in axial direction provided with fluid hole 4, and described sleeve pipe 3 is connected by fluid hole 4 and port lid 5
Connect；The junction of the fluid hole 4 and port lid 5 is provided with pad.
After the fluid hole 4 is connected with port lid 5, the bottom surface of described sleeve pipe 3 between the top surface of the port lid 5 between having
Gap.
The fluid hole 4 is connected through a screw thread with port lid 5, and specifically, the fluid hole 4 is provided with external thread section, described
Port lid 5 is provided with the internal thread hole section matched with the external thread section of fluid hole 4；The bottom of the port lid 5 is provided with pad, it is described go out
Fluid apertures 4 contacts through the internal thread hole section of port lid 5 with pad.Further, the port lid 5 is circular hollow structure, and pad covers
Cover the bottom of hollow structure in a circle.
The port lid 5 contacts with the bottom of outer tube 2, and the bottom of the outer tube 2 is in inverted round table structure, the port lid 5
The external diameter of internal thread hole section is more than the basal diameter of the inverted round table structure, and the height of the internal thread hole section of the port lid 5 is small
In the height of the inverted round table structure.
The lid 1, fluid hole 4 and port lid 5 are respectively positioned on the axis of described device；The outer tube 2, sleeve pipe 3 are
Bright material, scale is provided with the tube wall of described sleeve pipe 3.
As shown in Fig. 2 after described sleeve pipe 3 is taken out from outer tube 2, the fluid hole 4 is connected by pad and flowmeter 7
Connect.Preferably, one end of the flowmeter 7 is connected with stainless pin, and the stainless pin is the stainless pin with splay end, described
Stainless pin makes sleeve pipe 3 be connected with flowmeter 7 directly through pad.By controlling flowmeter 7 to control the row of liquid in sleeve pipe 3
Go out speed, liquid level is steadily slowly declined, keep water-oil interface stable.In use, the pad can be changed.
The outer tube 2 is installed with lid 1 by screw thread, specifically, the upper end of the outer tube 2 is provided with external thread section,
The internal thread segment matched with the external thread section of outer tube 2 is provided with the lid 1.
The top surface of described sleeve pipe 3 is provided with circle ring rack 6, inlet of the circle ring rack 6 along sleeve pipe 3 it is circumferentially disposed；
The internal diameter of the circle ring rack 6 is identical with the internal diameter of sleeve pipe 3, and the external diameter of the circle ring rack 6 is not more than the external thread section of outer tube 2
Diameter.Preferably, the external diameter of the circle ring rack 6 is equal to the diameter of the external thread section of outer tube 2.
The utility model is the device for being demulsified and separating for a small amount of vaccines, wherein, lid 1 is centrifuge tube screw thread lid；
Outer tube 2 is centrifuge tube outer tube, transparent material, centrifuge tube outer tube wall mirror-smooth；Sleeve pipe 3 is centrifuge tube sleeve pipe, transparent material
And carry scale；Centrifuge shield pipe outer wall mirror-smooth, with centrifuge tube outer tube wall seamless connection；Centrifuge tube cannula tip has circle
Ring support, centrifuge tube sleeve pipe can be secured within centrifuge tube outer tube.Fluid hole 4 is screw thread fluid hole, positioned at centrifuge shield
Bottom of the tube, liquid discharge rate can be controlled with connection flow gauge, liquid level is steadily declined, water-oil interface keeps clear.Port lid 5 is
Screw thread port lid, for sealing screw thread fluid hole；Containing pad, can change.The utility model whole device, it can bear at a high speed
Refrigerated centrifuge.
During using the utility model, vaccine and demulsifier are mixed after centrifugation, centrifuge tube sleeve pipe is taken out, is gone out by screw thread
Fluid apertures connection flow gauge, the aqueous phase of centrifuge shield bottom of the tube is set to be flowed out from screw thread fluid hole according to setting flow velocity to specified containers
In, the accurate collected volume for controlling sample.
Specific embodiment of the utility model is described above.It is to be appreciated that the utility model not office
It is limited to above-mentioned particular implementation, those skilled in the art can make a variety of changes or change within the scope of the claims,
This has no effect on substantive content of the present utility model.In the case where not conflicting, the spy in embodiments herein and embodiment
Sign can be arbitrarily mutually combined.
Claims (10)
1. a kind of device for being demulsified and separating for a small amount of vaccines, it is characterised in that described outer including outer tube (2) and sleeve pipe (3)
One end of pipe (2) is provided with lid (1), the inside installation sleeve pipe (3) and port lid (5) of the outer tube (2), described sleeve pipe (3) position
Between lid (1) and port lid (5)；The bottom that the port lid (5) is arranged on outer tube (2) is connected with sleeve pipe (3).
2. the device according to claim 1 for being demulsified and separating for a small amount of vaccines, it is characterised in that the outer tube (2)
Interior sidewall surface mirror-smooth, the outer side surface mirror-smooth of described sleeve pipe (3)；The outer side surface and outer tube of described sleeve pipe (3)
(2) interior sidewall surface fitting.
3. the device according to claim 1 or 2 for being demulsified and separating for a small amount of vaccines, it is characterised in that described sleeve pipe
(3) bottom surface is in axial direction provided with fluid hole (4), and described sleeve pipe (3) is connected by fluid hole (4) with port lid (5)；It is described
The junction of fluid hole (4) and port lid (5) is provided with pad.
4. the device according to claim 3 for being demulsified and separating for a small amount of vaccines, it is characterised in that the fluid hole
(4) after being connected with port lid (5), the bottom surface of described sleeve pipe (3) is to having gap between the top surface of the port lid (5).
5. the device according to claim 3 for being demulsified and separating for a small amount of vaccines, it is characterised in that the fluid hole
(4) it is connected through a screw thread with port lid (5), specifically, the fluid hole (4) is provided with external thread section, the port lid (5) is provided with
The internal thread hole section matched with the external thread section of fluid hole (4)；
The bottom of the port lid (5) is provided with pad, and the fluid hole (4) contacts through the internal thread hole section of port lid (5) with pad.
6. the device according to claim 5 for being demulsified and separating for a small amount of vaccines, it is characterised in that the port lid (5)
Contacted with the bottom of outer tube (2), the bottom of the outer tube (2) is in inverted round table structure, the internal thread hole section of the port lid (5)
External diameter is more than the basal diameter of the inverted round table structure, and the height of the internal thread hole section of the port lid (5) is less than the inversion
The height of frustum cone structure.
7. the device according to claim 3 for being demulsified and separating for a small amount of vaccines, it is characterised in that the lid (1),
Fluid hole (4) and port lid (5) are respectively positioned on the axis of described device；
The outer tube (2), sleeve pipe (3) are transparent material, and scale is provided with the tube wall of described sleeve pipe (3).
8. the device according to claim 3 for being demulsified and separating for a small amount of vaccines, it is characterised in that work as described sleeve pipe
(3) after being taken out from outer tube (2), the fluid hole (4) is connected by pad with flowmeter (7).
9. the device according to claim 1 for being demulsified and separating for a small amount of vaccines, it is characterised in that the outer tube (2)
Installed with lid (1) by screw thread, specifically, the outer tube (2) upper end is provided with external thread section, the lid (1) is interior
Side is provided with the internal thread segment matched with the external thread section of outer tube (2).
10. the device according to claim 9 for being demulsified and separating for a small amount of vaccines, it is characterised in that described sleeve pipe (3)
Top surface is provided with circle ring rack (6), inlet of the circle ring rack (6) along sleeve pipe (3) it is circumferentially disposed；
The internal diameter of the circle ring rack (6) is identical with the internal diameter of sleeve pipe (3), and the external diameter of the circle ring rack (6) is not more than outer tube
(2) diameter of external thread section.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720958030.2U CN207197881U (en) | 2017-08-02 | 2017-08-02 | The device for being demulsified and separating for a small amount of vaccines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720958030.2U CN207197881U (en) | 2017-08-02 | 2017-08-02 | The device for being demulsified and separating for a small amount of vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207197881U true CN207197881U (en) | 2018-04-06 |
Family
ID=61796108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720958030.2U Active CN207197881U (en) | 2017-08-02 | 2017-08-02 | The device for being demulsified and separating for a small amount of vaccines |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207197881U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117192048A (en) * | 2023-09-06 | 2023-12-08 | 武汉轻工大学 | Test tube device convenient for removing milk fat and rapidly measuring milk fat content |
-
2017
- 2017-08-02 CN CN201720958030.2U patent/CN207197881U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117192048A (en) * | 2023-09-06 | 2023-12-08 | 武汉轻工大学 | Test tube device convenient for removing milk fat and rapidly measuring milk fat content |
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