CN207107352U - A kind of conjuncted bottle cap being connected with solvent filter - Google Patents

Abstract

The utility model provides a kind of conjuncted bottle cap being connected with solvent filter, (10) are covered including lid, also include be connected to lid set (10) in cover core (9), the solvent filter (8) covered on cover core (9), the core sealing ring (11) being arranged between cover core (9) and solvent filter (8) or core seal convexity (21) and be arranged on cover core for sealed solvent bottle (6) seal；Fluid hole (13) and air admission hole (14) are provided with the cover core (9), the fluid hole (13) extends vertically through cover core (9), the cavity internal with solvent filter (8) connects, the air admission hole (14) is located on the outside of fluid hole (13), and the outlet of air admission hole (14) is located at solvent filter (8) periphery.The reasonable employment conjuncted bottle cap can effectively suppress the mobile phase mildew of liquid chromatogram, reduce the secondary failure of liquid chromatogram caused by mobile phase mildew.

Description

A kind of conjuncted bottle cap being connected with solvent filter

Technical field

The utility model belongs to liquid chromatography technology field, and in particular to a kind of conjuncted bottle cap being connected with solvent filter.

Background technology

Liquid chromatogram is high technology equipment common in modern measure science, is widely used in medicine, chemical industry, food, life The fields such as science.Mobile phase is part basic in liquid chromatogram, and mobile phase is generally contained in solvent bottle, passes through pipeline It is connected with the inlet one-way valve of chromatogram pump, one end that the pipeline stretches into solvent bottle is equipped with solvent filter, prevents particulate matter Into chromatogram pump, block chromatogram pipeline or cause failure of check valve.Solvent filter and bottle cap are typically separate in the prior art Two parts, bottle cap are generally screw top closure, are connected with solvent bottle bottleneck, and bottle cap top is provided with and allows the hole that pipeline passes through.Flowing Mutually it is placed in coordinative solvent bottle, solvent filter sinks to bottom of bottle, is flooded by mobile phase.

There is the common problem of the easy mildew of mobile phase in above-mentioned conventional solvent bottle structure, because liquid chromatogram is in open bar Used under part, various microorganisms in air be present, mobile phase mildew is made after contact flow phase, is further triggered after mobile phase mildew More secondary problems, such as cause blockings of solvent filter, mobile phase pipeline blockage, shift of retention time, filter element fail and The problems such as chromatographic column damage.Therefore fresh configuration mobile phase is generally required, avoids standing time long, do not exceed typically 24 hours.User must check in time mobile phase whether mildew and change mildew mobile phase, which adds safeguard protect Work is supported, chromatograph is frequently resulted in using interrupting, when serious mildew, also needs cleaning solvent bottle and the most important portion of filtrate solvent Part, the mobile phase that uses next time of pollution is prevented, further increase the complexity of maintenance and professional.

Utility model content

In view of the shortcomings of the prior art, it is this utility model discloses a kind of conjuncted bottle cap being connected with solvent filter Filter is connected by bottle cap with bottle cap, and the reasonable employment bottle cap can effectively reduce the frequency of mobile phase mildew, and mildew is greatly decreased The caused secondary failure of liquid chromatogram.

In order to solve the above technical problems, technical scheme is used by the utility model：

A kind of conjuncted bottle cap being connected with solvent filter, including lid set, in addition to the cover core being connected in lid set, cover on lid Solvent filter on core, the core sealing ring being arranged between cover core and solvent filter or core seal convexity and it is arranged on lid It is used for the seal of sealed solvent bottle on core；Fluid hole and air admission hole are provided with the cover core, the fluid hole extends vertically through lid Core, connected with the cavity inside solvent filter, the air admission hole is located on the outside of fluid hole, and the outlet of air admission hole is located at filtrate solvent Head periphery.

One of preferred scheme：The cover core is sequentially provided with filter connecting portion, bottle connecting portion and lid set and connected from top to bottom Socket part, the filter are arranged on the filter connecting portion periphery of cover core, and the filter connecting portion side wall is provided with the first groove, the core Sealing ring is arranged on the first groove；The bottle connecting portion is provided with the sealing angle for sealed solvent bottle；The cover core It is connected to by covering set connecting portion in the lid set.

The two of preferred scheme：The cover core is sequentially provided with filter connecting portion, bottle connecting portion and lid set and connected from top to bottom Socket part, the filter are arranged on the filter connecting portion periphery of cover core, and the filter connecting portion side wall is provided with outwardly flexibility Core seal convexity；The bottle connecting portion is provided with the sealing angle for sealed solvent bottle；The cover core is connected by covering set Socket part is connected in the lid set.

Further preferred scheme, the conjuncted bottle cap also include bottle sealing ring, are additionally provided with the bottle connecting portion of the cover core Second groove, second groove is positioned at the periphery of sealing angle；The bottle sealing ring is arranged on second groove.

Still further preferably scheme, the air admission hole are connected with air filter, the microorganism that can be crossed in air filtering, enter one Step prevents solvent mildew.

Still further preferably scheme, it is vertical between the inwall at filtrate solvent crown end and the outer wall on the cover core top Distance ＜ 30mm.This is apart from smaller, and for the inner volume of filter with regard to smaller, liquid contact surface product is bigger, can prevent bubble.

Lid set is with being preferably to be threadedly coupled between solvent bottle, after lid set is tightened with solvent bottle, covers the pressure applied by covering Cover core is pressed on solvent bottleneck.The effect of core sealing ring or core seal convexity between cover core and solvent filter is by cover core Effectively sealed with filter junction, being arranged on the seal on cover core for sealed solvent bottle there are diversified forms, can be sealing Circle can also be sealing angle etc., can seal solvent bottle.

In use, solvent bottle is connected with conjuncted bottle cap, upside down solvent bottle, mobile phase floods conjoined bottle in solvent bottle The solvent filter of lid, after chromatogram pump startup, mobile phase flows out under chromatogram pump negative pressure and solvent self gravitation effect, extraneous air Entered by air admission hole, keep balancing with atmospheric pressure；When chromatographic apparatus fulfils assignment, and does not need work for a long time, by solvent Bottle is put just, and mobile phase is that realization separates with solvent filter in solvent bottle, if mildew occurs for mobile phase in placement process, also will not Solvent filter is polluteed, can directly change solvent bottle or mobile phase, further reduces the frequency of mobile phase mildew.

The utility model is based on two general principles, one is allowing mobile phase to be in relative closure state, the air of outside Need just to enter mobile phase by air filter, so as to reduce microorganism pollution source；Next allows solvent filter can be with solvent bottle Middle mobile phase is conveniently separated, and when liquid chromatogram not operation, solvent filter is separated with flowing, accordingly even when mobile phase Mildew occurs in placement process, also will not solvent slop filter, can recover normal use after changing the mobile phase of mildew, will not Generation cross pollution.

Using principle above design prevent the Bottle cap structure of mobile phase mildew to be not easy to because, if in order to up to The purpose being separated to solvent filter with flowing, traditional solvent bottle structure is, it is necessary to solvent filter be lifted, disengaging mobile phase liquid Position, but the liquid so retained in solvent filter can flow out, and cause bigger cavity volume, after being placed again into mobile phase, greatly Amount bubble will enter mobile phase pipeline, have a strong impact on the check valve motion of chromatogram pump, also there is certain infringement to liquid-phase chromatographic column；Its Secondary mobile phase solvent bottle is usually glass material, and vial is when high temperature production, with the consume and temperature that make mould Variation, bottleneck planarization can morph with rounding property, and causing every batch of bottleneck, there is some difference, therefore to design of Sealing Structure Reliability requirement is high, and existing liquid chromatogram Bottle cap structure often results in poorly sealed；Other solvent filter is the important portion of liquid chromatogram Part, play a part of preventing particulate matter from entering chromatogram pump and pump back part, because filter possesses certain service life, therefore Need to change, so both need to consider that solvent filter changes the seal degree that conveniently, also consider filter contact surface；Also liquid phase The conventional Design Thinking of chromatographic solvent filter is that solvent filter separates with bottle cap, because mobile phase pipeline is needed through bottle cap, and Need often to be put into depth according to the height of solvent bottle adjustment solvent filter, therefore can not accomplish that pipeline is worn at mouth as sealing knot Structure.

The utility model has obvious practicality feature, compresses cover core by covering to cover, when avoiding loose unloading cover core, is connected to lid Drain pipe road and air inlet pipeline on core are wound；Cover core is bonded by surface convex portion (or sealing ring) with solvent bottleneck Sealing, it is adapted to the bottleneck of planarization very high tolerance scope；Solvent filter and cover core one, are not only convenient for using, and take The volume of very little；Solvent filter is in bottle mouth position, is inverted in use, because bottle mouth position diameter is much smaller than bottom of bottle, with conventional liquid phase color Spectrum mobile phase application method compares, and the disabled solvent in bottom is less, therefore more saves solvent；The utility model is greatly decreased Mobile phase mildew, 50mmol/L ammonium dihydrogen phosphate aqueous solutions (pH=7.0), routinely liquid chromatogram mobile phase application method, 28 Under DEG C degree environmental condition, occur visually visible mycelia in usual 48 hours, using mobile phase method of disposal of the present utility model, After usual 120 hours just can visual observations to mycelia, because general mobile phase is difficult to use more than one week, therefore the utility model is bright The aobvious effective utilization for improving mobile phase.The utility model has obvious novel features simultaneously, and its essence is by solvent bottle, flowing Phase pipeline, chromatogram pump housing and back-end component cavity are in the structure of a sealing, only pass through entering with air filtration head Stomata is communicated with the outside, and changes the use thinking that traditional chromatogram flow phase is in open laying state, solves flowing from source The common problem of phase mildew.

Brief description of the drawings

Fig. 1 is free from the conjuncted bottle cap structural representation of bottle sealing ring；

Fig. 2 is free from the conjuncted bottle cap decomposition texture schematic diagram of bottle sealing ring；

Fig. 3 is the conjuncted bottle cap structural representation of the sealing ring containing bottle；

Fig. 4 be the sealing ring containing bottle conjuncted bottle cap in a kind of structural representation of cover core；

Fig. 5 is the conjuncted bottle cap decomposition texture schematic diagram of the sealing ring containing bottle；

Fig. 6 be the sealing ring containing bottle conjuncted bottle cap in another cover core structural representation.

Embodiment

The utility model is described further with reference to embodiment.

As shown in Fig. 1 Fig. 2, a kind of conjuncted bottle cap being connected with solvent filter, including lid set (10), in addition to it is connected to lid The cover core (9) in (10) is covered, the solvent filter (8) covered on cover core (9), is arranged between cover core (9) and solvent filter (8) Core sealing ring (11) or core seal convexity (21) and be arranged on cover core be used for sealed solvent bottle (6) seal；It is described Fluid hole (13) and air admission hole (14) are provided with cover core (9), the fluid hole (13) extends vertically through cover core (9), with solvent filter (8) internal cavity connection, the air admission hole (14) is located on the outside of fluid hole (13), and the outlet of air admission hole (14) is located at solvent Filter (8) periphery.

As shown in figure 4, the cover core (9) be sequentially provided with from top to bottom filter connecting portion (15), bottle connecting portion (16) with And lid set connecting portion (20), the filter (8) are arranged on filter connecting portion (15) periphery of cover core, the filter connecting portion (15) Side wall is provided with the first groove (17), and the core sealing ring (11) is arranged on the first groove (17) place；The bottle connecting portion (16) It is provided with the sealing angle (18) for sealed solvent bottle；The cover core (9) is connected to the lid by covering set connecting portion (20) Cover in (10).

As shown in fig. 6, the cover core (9) be sequentially provided with from top to bottom filter connecting portion (15), bottle connecting portion (16) with And lid set connecting portion (20), the filter (8) are arranged on filter connecting portion (15) periphery of cover core, the filter connecting portion (15) Side wall is provided with outwardly flexible core seal convexity (21)；The bottle connecting portion (16), which is provided with, is used for sealed solvent bottle Sealing angle (18)；The cover core (9) is connected in the lid set (10) by covering set connecting portion (20).

As shown in Fig. 3 Fig. 4 Fig. 5, the conjuncted bottle cap (7) also includes bottle sealing ring (12), the bottle connecting portion of the cover core (16) the second groove (19) is additionally provided with, second groove (19) is positioned at the periphery of sealing angle (18)；The bottle sealing ring (12) it is arranged on the second groove (19) place.

Claims (6)

1. a kind of conjuncted bottle cap being connected with solvent filter, including lid set (10), it is characterized in that, in addition to it is connected to lid set (10) Interior cover core (9), the solvent filter (8) covered on cover core (9), the core being arranged between cover core (9) and solvent filter (8) sealing Enclose (11) or core seal convexity (21) and be arranged on the seal for being used for sealed solvent bottle (6) on cover core；The cover core (9) fluid hole (13) and air admission hole (14) are provided with, the fluid hole (13) extends vertically through cover core (9), interior with solvent filter (8) The cavity connection in portion, the air admission hole (14) is located on the outside of fluid hole (13), and the outlet of air admission hole (14) is located at solvent filter (8) periphery.

2. the conjuncted bottle cap being connected according to claim 1 with solvent filter, it is characterized in that, the cover core (9) is from top to bottom It is sequentially provided with filter connecting portion (15), bottle connecting portion (16) and lid set connecting portion (20), the filter (8) and is arranged on cover core Filter connecting portion (15) periphery, filter connecting portion (15) side wall is provided with the first groove (17), the core sealing ring (11) It is arranged on the first groove (17) place；The bottle connecting portion (16) is provided with the sealing angle (18) for sealed solvent bottle；Institute State cover core (9) and be connected to by covering set connecting portion (20) in the lid set (10).

3. the conjuncted bottle cap being connected according to claim 1 with solvent filter, it is characterized in that, the cover core (9) is from top to bottom It is sequentially provided with filter connecting portion (15), bottle connecting portion (16) and lid set connecting portion (20), the filter (8) and is arranged on cover core Filter connecting portion (15) periphery, filter connecting portion (15) side wall is provided with outwardly flexible core seal convexity (21)；The bottle connecting portion (16) is provided with the sealing angle (18) for sealed solvent bottle；The cover core (9) is covered by covering Connecting portion (20) is connected in the lid set (10).

4. the conjuncted bottle cap being connected according to one of claim 1-3 with solvent filter, it is characterized in that, the conjuncted bottle cap (7) also include bottle sealing ring (12), the second groove (19), second groove are additionally provided with the bottle connecting portion (16) of the cover core (19) positioned at the periphery of sealing angle (18)；The bottle sealing ring (12) is arranged on the second groove (19) place.

5. the conjuncted bottle cap being connected according to one of claim 1-3 with solvent filter, it is characterized in that, the air admission hole (14) It is connected with air filter.

6. the conjuncted bottle cap being connected according to one of claim 1-3 with solvent filter, it is characterized in that, the solvent filter (8) the vertical range ＜ 30mm between the inwall on top and the outer wall on the cover core (9) top.