CN207083809U - A kind of integration aptitude tests device for cerebral ischemia mouse - Google Patents

A kind of integration aptitude tests device for cerebral ischemia mouse Download PDF

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Publication number
CN207083809U
CN207083809U CN201721063147.0U CN201721063147U CN207083809U CN 207083809 U CN207083809 U CN 207083809U CN 201721063147 U CN201721063147 U CN 201721063147U CN 207083809 U CN207083809 U CN 207083809U
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China
Prior art keywords
frame
glass
integration
cerebral ischemia
grid
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Expired - Fee Related
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CN201721063147.0U
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Chinese (zh)
Inventor
孔祥英
林娜
苏晓慧
孟翔鹤
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Institute of Materia Medica of CAMS
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Institute of Materia Medica of CAMS
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Priority to CN201721063147.0U priority Critical patent/CN207083809U/en
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Abstract

The utility model provides a kind of integration aptitude tests device for cerebral ischemia mouse,Including hollow grid,Frame sliding block,Glass bracket,Glass plate,Fixed glass blocks,Rotating shaft,Inserted rotating cylinder and connecting rod,Hollow grid is arranged on Grid Edge inframe portion,Frame sliding block is arranged on grid frame left side and right side,The design achieves conveniently removing and installing for hollow out test grid mechanism,Region for the integration aptitude tests of cerebral ischemia mouse,Glass bracket is arranged on cloche wall lower surface,Glass plate is arranged in glass bracket,Fixed glass blocks is arranged on the inside of cloche wall,This design provides the function of protection mouse,Rotating shaft is arranged on A-frame top,Inserted rotating cylinder is connected by connecting rod with rotating shaft,This design provides the function of second of observation focal cerebral ischemia impaired exercise integration ability,The utility model is easy to use,It is easy to operation,Stability is good,Reliability is high.

Description

A kind of integration aptitude tests device for cerebral ischemia mouse
Technical field
A kind of integration aptitude tests device for cerebral ischemia mouse of the utility model, belong to experimental animal fortune The field of dynamic integration ability test.
Background technology
Ischemic brain damage is blocked by cerebral vessels so that a kind of irreversible damage that the blood vessel institute blood supply brain area occurs Wound.The disease has become global first big disabling disease, the third-largest fatal disease.Ischemic brain damage has become global god Through scientific basic and clinical staff focus of attention.
The hollow grid for the integration aptitude tests of cerebral ischemia mouse is difficult disassembly, cleaning in the prior art, All it is integrally fixed on support, the integration aptitude tests experimental provision for cerebral ischemia mouse does not all have in the prior art Safeguard function, mouse have the danger of landing in motion process, observe the integration of cerebral ischemia mouse in the prior art The mechanism of aptitude tests is single, can not carry out kinds of experiments analysis, so being badly in need of a kind of fortune for cerebral ischemia mouse Dynamic integration ability test device, to solve the above problems.
Utility model content
In view of the deficienciess of the prior art, the utility model purpose is to provide a kind of fortune for cerebral ischemia mouse Dynamic integration ability test device, to solve the problems mentioned in the above background technology, the utility model is easy to use, is easy to grasp Make, stability is good, and reliability is high.
To achieve these goals, the utility model is to realize by the following technical solutions:One kind is used for cerebral ischemia Damage the integration aptitude tests device of mouse, including apparatus main body, hollow out test grid mechanism, cover plate mechanism and Mouse rotating cylinder exercise test mechanism, described device main body include feet and table frame, and the table frame is arranged on feet upper surface, described Hollow out test grid mechanism is arranged on table frame upper surface, and the hollow out test grid mechanism includes hollow grid, grid frame, side Frame sliding block, limited block and chute, the hollow grid are arranged on Grid Edge inframe portion, and the frame sliding block is arranged on Grid Edge Frame left side and right side, the limited block are arranged on frame slip front face and rear end face, and the chute is arranged in table frame Side left side and right side, the cover plate mechanism are arranged on table frame outward flange position, and the cover plate mechanism includes glass Glass cover wall, glass bracket, glass plate, fixed glass blocks and turnover hinge, the glass bracket are arranged on by turnover hinge Cloche wall lower surface, the glass plate are arranged in glass bracket, and the fixed glass blocks is arranged on the inside of cloche wall, institute State mouse rotating cylinder exercise test mechanism and be arranged on table frame upper surface right positions, the mouse rotating cylinder exercise test mechanism includes support Plate, A-frame, rotating shaft, inserted rotating cylinder and connecting rod, the supporting plate are arranged on table frame upper surface right positions, the triangle Support is arranged on supporting plate upper surface centre position, and the rotating shaft is arranged on A-frame top, and the inserted rotating cylinder passes through company Bar is connected with rotating shaft.
Further, the feet lower surface is provided with rubber blanket.
Further, the glass plate is arranged right below video camera, and the table frame front end is provided with video camera.
Further, the glass bracket has four, and four glass brackets are evenly distributed on front side of table frame and rear side Lower surface.
Further, the fixed glass blocks has four, and two fixed glass blocks are arranged on left inside cloche wall End face, two fixed glass blocks are arranged on right side inside cloche wall.
Further, glass plate and the glass bracket contact position is provided with cushioning piece.
Further, the limited block is arranged on frame sliding block by rotating shaft.
The beneficial effects of the utility model:A kind of integration ability for cerebral ischemia mouse of the present utility model Test device, because the utility model with the addition of hollow grid, grid frame, frame sliding block and limited block, the design achieves Hollow out test grid mechanism conveniently removes and installs, and solves the problems, such as that original hollow grid is difficult to disassembly, cleaning.
, should because the utility model with the addition of cloche wall, glass bracket, glass plate, fixed glass blocks and turnover hinge Design realizes mouse safeguard function in experimentation, when solving original device experiment, it is necessary to artificial careful nurse mouse Problem.
Because the utility model with the addition of supporting plate, A-frame, rotating shaft, inserted rotating cylinder and connecting rod, the design achieves The function of second of observation focal cerebral ischemia impaired exercise integration ability, it is insufficient to solve original single Germicidal efficacy data Problem.
Because the utility model with the addition of rubber blanket, this design provides the function that asks safely in installation moving process, because The utility model with the addition of video camera, this design provides detailed record experimentation and the function of data, because of the utility model Fixed block is with the addition of, this design provides the fixing function of cover plate mechanism, because the utility model with the addition of bracket, the design Provide glass plate is horizontally mounted fixing function, and because the utility model with the addition of cushioning piece, this design provides glass plate The function that safety does not slide in experimentation, it is rotatable this design provides limited block because the utility model with the addition of rotating shaft Function, the utility model is easy to use, easy to operation, and stability is good, and reliability is high.
Brief description of the drawings
By reading the detailed description made with reference to the following drawings to non-limiting example, other spies of the present utility model Sign, objects and advantages will become more apparent upon:
Fig. 1 is a kind of structural representation of integration aptitude tests device for cerebral ischemia mouse of the utility model Figure;
Fig. 2 is that hollow out is tested in a kind of integration aptitude tests device for cerebral ischemia mouse of the utility model The structural representation of grid mechanism;
Fig. 3 is cover plate in a kind of integration aptitude tests device for cerebral ischemia mouse of the utility model The structural representation of mechanism;
Fig. 4 is mouse rotating cylinder in a kind of integration aptitude tests device for cerebral ischemia mouse of the utility model Exercise test mechanism structure schematic diagram;
In figure:1- feets, 2- table frame, 3- hollow outs test grid mechanism, 4- cover plates mechanism, the motion of 5- mouse rotating cylinder are surveyed Test-run a machine structure, 31- hollow grids, 32- grids frame, 33- frames sliding block, 34- limited blocks, 35- chutes, 41- cloches wall, 42- Glass bracket, 43- glass plates, 44- fix glass blocks, 45- turnover hinges, 51- supporting plates, 52- A-frames, 53- rotating shafts, 54- Inserted rotating cylinder, 55- connecting rods.
Embodiment
Technological means, creation characteristic, reached purpose and effect to realize the utility model are easy to understand, below With reference to embodiment, the utility model is expanded on further.
Fig. 1-Fig. 4 is referred to, the utility model provides a kind of technical scheme:A kind of motion for cerebral ischemia mouse Integration ability test device, including apparatus main body, hollow out test grid mechanism 3, cover plate mechanism 4 and the motion of mouse rotating cylinder Mechanism for testing 5, apparatus main body include feet 1 and table frame 2, and table frame 2 is arranged on the upper surface of feet 1.
Hollow out test grid mechanism 3 is arranged on the upper surface of table frame 2, and hollow out test grid mechanism 3 includes hollow grid 31, net Lattice frame 32, frame sliding block 33 and limited block 34, hollow grid 31 are arranged on inside grid frame 32, and frame sliding block 33 is set In the left side of grid frame 32 and right side, limited block 34 is arranged on the front end face of frame sliding block 33 and rear end face, and chute 35 is set In the inside left-end face of table frame 2 and right side, the design achieves conveniently removing and installing for hollow out test grid mechanism 3.
Cover plate mechanism 4 is arranged on the outward flange position of table frame 2, and cover plate mechanism 4 includes cloche wall 41, glass holder Frame 42, glass plate 43, fixed glass blocks 44 and turnover hinge 45, glass bracket 42 are arranged on cloche by turnover hinge 45 The lower surface of wall 41, glass plate 43 are arranged in glass bracket 42, and fixed glass blocks 44 is arranged on the inner side of cloche wall 41, the design Provide the function that mouse is protected in experimentation.
Mouse rotating cylinder exercise test mechanism 5 is arranged on the upper surface right positions of table frame 2, mouse rotating cylinder exercise test mechanism 5 Including supporting plate 51, A-frame 52, rotating shaft 53, inserted rotating cylinder 54 and connecting rod 55, it is right that supporting plate 51 is arranged on the upper surface of table frame 2 Side position, A-frame 52 are arranged on the upper surface centre position of supporting plate 51, and rotating shaft 53 is arranged on the top of A-frame 52, inserted Rotating cylinder 54 is connected by connecting rod 55 with rotating shaft 53, and this design provides second of observation focal cerebral ischemia impaired exercise integration ability Function.
The lower surface of feet 1 is provided with rubber blanket, and glass plate 43 is arranged right below video camera, and the front end of table frame 2 is provided with video camera, glass Glass bracket 42 has four, and four glass brackets 42 are evenly distributed on the front side of table frame 2 and rear side lower surface, fixed glass blocks 44 There are four, two fixed glass blocks 44 are arranged on the inside left side lower edge position of cloche wall 41, two fixations Glass blocks 44 is arranged on the inside right side lower edge position of cloche wall 41, and glass plate 43 and the contact position of glass bracket 42 are provided with Cushioning piece, limited block 34 are arranged on frame sliding block 33 by rotating shaft.
Embodiment:In progress in use, experimenter first is checked the utility model, check whether and deposit In defect, it can not just carry out using if there is defect, now need to notify maintenance personal to be repaired, if do not deposited It can be carried out using if problem, as experimenter in use, hollow grid 31 is fixed on inside grid frame 32, net Lattice frame 32 is arranged on the inner upper end face of table frame 2 by frame sliding block 33, and rotary spacing block 34 fixes whole hollow out Test Network Lattice mechanism 3, this design provides the region of the integration aptitude tests for cerebral ischemia mouse conveniently removed and installed.
As experimenter in use, cloche wall 41 is arranged on into the outer edge of table frame 2, adjusting fixed glass blocks 44 makes to prevent It is firm to protect the installation of glass mechanism 4, glass bracket 42 is put down by turnover hinge 45, glass plate 43 is arranged on glass bracket 42 On end face, video camera is separately positioned on the underface of glass plate 43 and the front end of table frame 2, preparation starts to test, by cerebral ischemia Experiment adult male mice afterwards, is positioned over the one end of hollow out test grid mechanism 3, and trained experiment mice freely exists Hollow out test grid mechanism 3 moves, when mouse is moved to 31 edge of hollow grid, due to cloche wall 41 presence mouse not It can drop down, mouse four limbs were fallen into the hole of hollow grid 31 when can not move at that time, can be trampled the relay of glass plate 43 and were returned to and engrave Continued to move on abortive haul lattice 31, while open video camera, record the video data of 1 minute, record analysis experimental data, the design Provide the function that mouse is protected in experimentation.
As experimenter in use, by the experiment adult male mice of health, subordinate in inserted rotating cylinder 54 is positioned over End face, mouse are freely run in inserted rotating cylinder 54, and running for mouse drives the rotation of inserted rotating cylinder 54, inserted rotating cylinder 54 rotate the rotation that rotating shaft 53 is driven by connecting rod 55, and the rotation of inserted rotating cylinder 54 embodies mouse movement integration ability, together Shi Kaiqi video cameras, the video data of recording 1 minute, record analysis experimental data, then the experiment bull of health is small Mouse changes cerebral ischemia experiment adult male mice into, carries out above-mentioned experiment, two groups of data is analyzed, the design Provide the function of second of observation focal cerebral ischemia impaired exercise integration ability.
The advantages of general principle and principal character of the present utility model and the utility model has been shown and described above, for For those skilled in the art, it is clear that the utility model is not limited to the details of above-mentioned one exemplary embodiment, and without departing substantially from this In the case of the spirit or essential attributes of utility model, the utility model can be realized in other specific forms.Therefore, no matter From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the utility model is by institute Attached claim rather than described above limit, it is intended that will fall in the implication and scope of the equivalency of claim All changes are included in the utility model.Any reference in claim should not be considered as to the involved right of limitation It is required that.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment is only wrapped Containing an independent technical scheme, this narrating mode of specification is only that those skilled in the art should for clarity Using specification as an entirety, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art It is appreciated that other embodiment.

Claims (7)

1. a kind of integration aptitude tests device for cerebral ischemia mouse, including apparatus main body, hollow out test grid Mechanism (3), cover plate mechanism (4) and mouse rotating cylinder exercise test mechanism (5), it is characterised in that:Described device main body bag Feet (1) and table frame (2) are included, the table frame (2) is arranged on feet (1) upper surface;
The hollow out test grid mechanism (3) is arranged on table frame (2) upper surface, and the hollow out test grid mechanism (3) includes engraving Abortive haul lattice (31), grid frame (32), frame sliding block (33), limited block (34) and chute (35), the hollow grid (31) Internal installed in grid frame (32), the frame sliding block (33) is arranged on grid frame (32) left side and right side, described Limited block (34) is arranged on frame sliding block (33) front end face and rear end face, and the chute (35) is arranged on table frame (2) inside left-end On face and right side;
The cover plate mechanism (4) is arranged on table frame (2) outward flange position, and the cover plate mechanism (4) includes cloche Wall (41), glass bracket (42), glass plate (43), fixed glass blocks (44) and turnover hinge (45), the glass bracket (42) cloche wall (41) lower surface is arranged on by turnover hinge (45), the glass plate (43) is arranged on glass bracket (42) Interior, the fixed glass blocks (44) is arranged on the inside of cloche wall (41);
The mouse rotating cylinder exercise test mechanism (5) is arranged on table frame (2) upper surface right positions, and the mouse rotating cylinder motion is surveyed Test-run a machine structure (5) includes supporting plate (51), A-frame (52), rotating shaft (53), inserted rotating cylinder (54) and connecting rod (55), the support Plate (51) is arranged on table frame (2) upper surface right positions, and the A-frame (52) is arranged on supporting plate (51) upper surface interposition Put, the rotating shaft (53) is arranged on A-frame (52) top, and the inserted rotating cylinder (54) passes through connecting rod (55) and rotating shaft (53) connect.
2. a kind of integration aptitude tests device for cerebral ischemia mouse according to claim 1, its feature It is:Feet (1) lower surface is provided with rubber blanket.
3. a kind of integration aptitude tests device for cerebral ischemia mouse according to claim 1, its feature It is:The glass plate (43) is arranged right below video camera, and table frame (2) front end is provided with video camera.
4. a kind of integration aptitude tests device for cerebral ischemia mouse according to claim 1, its feature It is:The glass bracket (42) is provided with four, and four glass brackets (42) are evenly distributed on front side of table frame (2) and rear side Lower surface.
5. a kind of integration aptitude tests device for cerebral ischemia mouse according to claim 1, its feature It is:The fixed glass blocks (44) is provided with four, and it is internal that two fixed glass blocks (44) are arranged on cloche wall (41) Left side, two fixed glass blocks (44) are arranged on the internal right side of cloche wall (41).
6. a kind of integration aptitude tests device for cerebral ischemia mouse according to claim 1, its feature It is:The glass plate (43) and glass bracket (42) contact position are provided with cushioning piece.
7. a kind of integration aptitude tests device for cerebral ischemia mouse according to claim 1, its feature It is:The limited block (34) is arranged on frame sliding block (33) by rotating shaft.
CN201721063147.0U 2017-08-24 2017-08-24 A kind of integration aptitude tests device for cerebral ischemia mouse Expired - Fee Related CN207083809U (en)

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Application Number Priority Date Filing Date Title
CN201721063147.0U CN207083809U (en) 2017-08-24 2017-08-24 A kind of integration aptitude tests device for cerebral ischemia mouse

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201721063147.0U CN207083809U (en) 2017-08-24 2017-08-24 A kind of integration aptitude tests device for cerebral ischemia mouse

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111789036A (en) * 2020-08-21 2020-10-20 上海交通大学医学院附属瑞金医院 Mouse sleep management device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111789036A (en) * 2020-08-21 2020-10-20 上海交通大学医学院附属瑞金医院 Mouse sleep management device

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20180313

Termination date: 20190824

CF01 Termination of patent right due to non-payment of annual fee