CN207046017U - Barrier package bag available for subsidiary infusion bag inner chamber temperature - Google Patents

Barrier package bag available for subsidiary infusion bag inner chamber temperature Download PDF

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Publication number
CN207046017U
CN207046017U CN201720749500.4U CN201720749500U CN207046017U CN 207046017 U CN207046017 U CN 207046017U CN 201720749500 U CN201720749500 U CN 201720749500U CN 207046017 U CN207046017 U CN 207046017U
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China
Prior art keywords
bag
closure
infusion bag
barrier package
sealed
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CN201720749500.4U
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Chinese (zh)
Inventor
柏仁国
刘文军
罗成鑫
刘思川
谭鸿波
葛均友
钟亚玲
王松
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Sichuan Kelun Pharmaceutical Co Ltd
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Sichuan Kelun Pharmaceutical Co Ltd
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Abstract

The utility model discloses a kind of barrier package bag available for subsidiary infusion bag inner chamber temperature, mouth is connect comprising packaging bag body and probe;Sealed frame on auxiliary bag body, which encloses, is connected to chamber resettling's surrounding;Probe connects mouth and includes connecting tube, insertion pipe, sealing-plug, closure, the both ends difference buckling end and sealed end of closure, and closure is provided with the button platform to convex in one end of buckling end, and closure offers probe interface on sealed end.The establishment that the utility model can save clean area is cost-effective, can be on the premise of the vacuum environment set not be destroyed between infusion bag and barrier package bag in sterilization process, so that the temperature of medicine is measured in the probe insertion infusion bag of measurement temperature in medicine, so as to detect the sterilising temp whether medicine reaches required, ultimate guarantee medicine can reach defined Sterile standard.

Description

Barrier package bag available for subsidiary infusion bag inner chamber temperature
Technical field
The barrier package bag technique field of infusion bag is the utility model is related to, more particularly to it is a kind of defeated available for subsidiary The barrier package bag of liquid bag inner chamber temperature.
Background technology
Flow of infusate, which must assure that, during due to Clinical practice reaches Sterile standard, therefore is filled when flow of infusate produces in pharmaceutical factory After infusion bag, the infusion bag product equipped with flow of infusate will be sterilized, transporting and storing to ensure after sterilizing During, infusion bag is not in contact with air, avoids the gnotobasis in infusion bag from being destroyed, generally can after sterilization by Infusion bag loads a barrier package bag, and the air in barrier package bag is drawn into it and reaches certain vacuum, so as to Infusion bag and its flow of infusate of inside are in gnotobasis before guarantee Clinical practice.
In the prior art, it is general to be using high-temperature sterilization principle sterilizing as shown in Figure 1, specific implementation process:Sterilizing Product, in the sterilization process needed for host computer setting, starts sterilizing program, from one bag of product according to often predetermined load mode Bag is referred to as sterilizing, control machine is referred in bag after the detection of fluid temperature by temperature measurement probe to sterilizing, control heat exchange Device controls the temperature of shower water, and shower water sprayed and carried out to product all in sterilizer in the presence of circulating pump Heating, reaches required sterilising temp to the product temperature that temperature measurement probe measures, so as to realize sterilizing, and in sterilizing program Afterwards, in standard compliant clean area, the infusion bag product after sterilizing is loaded in barrier package bag.
The defects of this method is present loads barrier to need to create a standard compliant clean area after being sterilized for product Packaging bag, and create clean area and make it that investment increases, and causes cost to raise.
Therefore, also have to use in the prior art and before sterilization load infusion bag and Related product in barrier package bag, Then its entirety is sterilized again, so as to eliminate the establishment of clean area, but temperature control probe is examined in sterilizing program Survey when sterilizing refers to fluid temperature in bag, it is necessary to which transfusion could be inserted from the probe inlet of infusion bag by first puncturing barrier package bag Its internal liquid temperature is detected in bag.Puncture the vacuum that barrier package bag can be destroyed in barrier package bag, cause infusion bag with Air between barrier bag is uncontrollable, so as to which the infusion bag product and the sterilizing that cause normally to sterilize refer to bag in sterilization process Middle state in which is inconsistent, and sterilizing may be caused to reach the sterilization process temperature of setting with reference to the temperature in bag, and normally goes out The infusion bag product of bacterium is unable to reach sterilising temp, and sterilization time will be caused not enough to lead to not ensure that infusion bag product reaches mark Accurate germ-free condition.
Utility model content
Part in view of the shortcomings of the prior art, the purpose of this utility model are that providing one kind can be used for subsidiary The barrier package bag of infusion bag inner chamber temperature, it may be such that infusion bag product is not destroying transfusion bag body and barrier using the auxiliary bag Between packaging bag under the precondition of vacuum, the temperature value of liquid medicine in infusion bag is measured, finally realizes in infusion bag and infuses The sterilizing of medicine.
The purpose of this utility model is achieved through the following technical solutions:
A kind of barrier package bag available for subsidiary infusion bag inner chamber temperature, connect comprising packaging bag body and probe Mouth;The auxiliary bag body includes sealed frame and chamber resettling, and the sealed frame, which encloses, is connected to chamber resettling's surrounding;Institute State probe and connect mouth and include connecting tube, insertion pipe, sealing-plug, closure, wherein, the both ends of the connecting tube be respectively insertion end and Interface end;The both ends of the insertion pipe are respectively inserted terminal and built-in end, and the inwall of the insertion pipe is from the inserted terminal to institute State built-in end and form the second order stepped hole that aperture increases successively, the inner chamber of the connecting tube is sequentially formed the first cavity, second Cavity, the 3rd cavity, boss outer rim is formed when the outer wall of the 3rd cavity connects with the outer wall of second cavity;It is described close The both ends difference buckling end and sealed end of capping, the closure are provided with the button platform to convex, institute in one end of the buckling end State closure and offer probe interface on the sealed end;
The insertion end is placed in the chamber resettling through the sealed frame;The inserted terminal is closed to be plugged in institute State in interface end, the sealing-plug is tightly packed in the closure, described when the closure fastens with the insertion pipe Sealing-plug is embedded in the built-in end, and the button platform on the closure is closed to be buckled in the boss outer rim;
In use, the infusion bag equipped with flow of infusate is placed in the chamber resettling of the barrier package bag, and by infusion bag Probe access mouth and barrier package bag probe connect mouth insertion end to it, the probe of measurement temperature is then passed through into insertion again The probe of barrier package bag connects mouth and the probe access mouth of infusion bag, so as to insert in infusion bag the temperature for measuring internal flow of infusate Degree.
Further, location sealing block is provided with the sealed frame, when the connecting tube inserts the chamber resettling, The outer wall of insertion end described in location sealing block sealed envelope described in the sealed frame, ensureing connecting tube insertion chamber resettling When, while the sealing of the barrier package bag is not destroyed, it a certain degree of can also play the work for reinforcing the barrier package bag With.
Further, several reinforcing sealing blocks are provided with the sealed frame, in practice, can be according to demand in sealing strip The reinforcing sealing block of respective numbers is added in frame, and the shape for reinforcing sealing block also can be selected freely.
Further, the profile of the barrier package bag is rectangle, in practice, can be suitable from other according to demand Shape.
The utility model compared with the prior art, has the advantage that and had the beneficial effect that:Before sterilization, i.e., infusion bag is sealed Loaded in barrier package bag, the establishment of clean area can be saved, so as to cost-effective, and the barrier package bag connects provided with probe Mouth, can be on the premise of the vacuum environment set not be destroyed between infusion bag and barrier package bag in sterilization process so that measurement The temperature of medicine is measured in the probe insertion infusion bag of temperature in medicine, so as to detect the sterilizing temperature whether medicine reaches required Degree, ultimate guarantee medicine can reach defined Sterile standard.
Brief description of the drawings
Fig. 1 is the schematic diagram using the method that heat sterilization is directly carried out to infusion bag;
Fig. 2 is the close-up schematic view at A in Fig. 1;
Fig. 3 is the schematic diagram of barrier package bag of the present utility model;
Fig. 4 is the schematic diagram that probe of the present utility model connects mouth;
Fig. 5 is that the schematic diagram after infusion bag is placed in barrier package bag of the present utility model.
Wherein, it is entitled corresponding to the reference in accompanying drawing:
1- packaging bag bodies, 2- probes connect mouth, 3- location sealing blocks, 4- sealing and reinforcing blocks, 11- sealed frames, 12- appearances Put chamber, 21- connecting tubes, 22- insertion pipes, 23- sealing-plugs, 24- closures, 211- insertion ends, 212- interface ends, 221- grafting End, 222- built-in ends, 100- sterilizers, 101- vehicle of sterilization, 102- shower waters, 103- temperature measurement probes, 201- productions subject to sterilization Product, 202- sterilizings refer to bag, and 203-, which pops one's head in, accesses mouth, 301- heat exchangers, 302- circulating pumps, 303- control systems, and 304- is upper Machine.
Embodiment
The utility model is described in further detail with reference to embodiment:
As shown in Fig. 1~Fig. 2, typically using high temperature spray sterilizing when being sterilized to infusion bag product, specifically, will first wait to go out Bacterium product 201 is loaded on the vehicle of sterilization 101 in sterilizer 100 according to often predetermined load mode, and subject to sterilization from one Product 201 refers to bag 202 as sterilizing, and required sterilization process is set in host computer 304 and starts sterilizing program, and different Sterilization process in set the sterilising temp of various criterion.Control system 303 inserts sterilizing ginseng by temperature measurement probe 103 The result that the sterilizing detected after the probe access mouth 203 on bag 202 refers to fluid temperature in bag 202 is examined, to control heat exchanger 301, heat exchanger 301 can control shower water 102 to be warming up to default temperature, while shower water 102 is in the presence of circulating pump 302 Product all in sterilizer 100 is sprayed and heated, product 201 subject to sterilization and sterilizing is reached with reference to liquid in bag 202 To required sterilising temp, so as to realize sterilizing.
In order to ensure infusion bag product during transport and storage, infusion bag is not in contact with air, so as to avoid Gnotobasis in infusion bag is destroyed, and generally infusion bag product can be loaded into a barrier bag after sterilization or before sterilizing Pack, and the air in barrier package bag is evacuated to certain vacuum, ensures the defeated of infusion bag before Clinical practice and its inside Liquid medicine is in gnotobasis, and for different decoctions, the scope of the vacuum is different, and occurrence is needed according to decoction Type determines.
Embodiment
As shown in Fig. 3~Fig. 4, a kind of barrier package bag available for subsidiary infusion bag inner chamber temperature, packaging is included Bag body 1 and probe connect mouth 2, and the profile of packaging bag body 1 is designed as into rectangle in the present embodiment, in practice, can be according to need Ask and select other suitable shapes, set Packed chamber resettling 12 in packaging bag body 1, sealed frame 11 enclose be connected to it is accommodating The surrounding of chamber 12, in order to strengthen the steadiness of sealed frame 11, the overall sealing of barrier package bag is ensured, can be in sealed frame Several sealing and reinforcing blocks 4 are added in 11, the sealing and reinforcing block 4 of a bar shaped has only been added in the present embodiment, in practice can root The sealing and reinforcing block 4 of respective amount is added in different positions according to demand, and shape can also design according to the actual requirements, probe Connect mouth 2 and include connecting tube 21, insertion pipe 22, sealing-plug 23, closure 24, the both ends of connecting tube 21 are respectively the He of insertion end 211 Interface end 212;The both ends of insertion pipe 22 are respectively inserted terminal 221 and built-in end 222, and the inwall of insertion pipe 22 is from inserted terminal 221 The second order stepped hole increased successively to the formation of built-in end 222 aperture, makes the inner chamber of connecting tube 21 sequentially form the first cavity, second Cavity, the 3rd cavity, boss outer rim is formed when the outer wall of the 3rd cavity connects with the outer wall of the second cavity;The both ends of closure 24 Buckling end and sealed end respectively, closure 24 are provided with the button platform to convex in one end of buckling end 241, and closure 24 is in sealed end On offer probe interface.
Insertion end 211 is placed in chamber resettling 12 through sealed frame 11;Inserted terminal 221 is closed to be plugged in interface end In 212, the sealing of barrier package bag will not be destroyed during sealed frame 11 in order to ensure that insertion end 211 passes through, in sealed frame Location sealing block 3 is provided with 11, when connecting tube 21 inserts chamber resettling 12, the sealed bundle of location sealing block 3 in sealed frame 11 The outer wall of insertion end 211 is wrapped up in, while location sealing block 3 can also play a part of reinforcing sealed frame 11 to a certain extent, it is close Blocking 23 is tightly packed, and in closure 24, when closure 24 fastens with insertion pipe 22, sealing-plug 23 is embedded in built-in end 222, Button platform on closure 24 is closed to be buckled in boss outer rim.
As shown in figure 5, in production, before being sterilized to infusion bag, i.e., infusion bag is packaged in barrier package bag In chamber resettling 12, meanwhile, the probe access mouth 203 in infusion bag is alignd with connecting tube 21, then by chamber resettling 12 Air is extracted out, and the vacuum of demand is reached to chamber resettling 12, then will be packaged after barrier package bag and its inside it is defeated After liquid bag is together loaded on the vehicle of sterilization 101 in sterilizer 100 according to predetermined load mode, and selection one is packaged Barrier package bag starts sterilizing program as reference experiment product after required sterilization process is set in host computer 304.Control When system 303 detects medicine temperature in infusion bag by temperature measurement probe 103, temperature measurement probe 103 is firstly inserted into spy Pin connects the probe access mouth 203 that mouth 2 is then passed through setting on the bag body of reference experiment product, you can stretch into infusion bag in medicine so as to Measure the temperature of medicine.
Preferred embodiment of the present utility model is the foregoing is only, it is all at this not to limit the utility model All any modification, equivalent and improvement made within the spirit and principle of utility model etc., should be included in the utility model Protection domain within.

Claims (4)

1. the barrier package bag available for subsidiary infusion bag inner chamber temperature, it is characterised in that comprising packaging bag body (1) and Probe connects mouth (2);
The packaging bag body (1) includes sealed frame (11) and chamber resettling (12), and the sealed frame (11), which is enclosed, is connected to institute State chamber resettling (12) surrounding;
The probe connects mouth (2) and includes connecting tube (21), insertion pipe (22), sealing-plug (23), closure (24), wherein, it is described The both ends of connecting tube (21) are respectively insertion end (211) and interface end (212);The both ends of the insertion pipe (22) are respectively grafting (221) and built-in end (222) are held, the inwall of the insertion pipe (22) is from the inserted terminal (221) to the built-in end (222) shape The second order stepped hole increased successively into aperture, the inner chamber of the connecting tube (21) is set to sequentially form the first cavity, the second cavity, Three cavitys, boss outer rim is formed when the outer wall of the 3rd cavity connects with the outer wall of second cavity;The closure (24) both ends difference buckling end and sealed end, the closure (24) is provided with one end of the buckling end to button platform, described Closure (24) offers probe interface on the sealed end;
The insertion end (211) is placed in the chamber resettling (12) through the sealed frame (11);The inserted terminal (221) closed to be plugged in the interface end (212), the sealing-plug (23) is tightly packed in the closure (24), institute When stating closure (24) with the insertion pipe (22) fastening, the embedded built-in end (222) of the sealing-plug (23), the sealing The button platform on lid (24) closed is buckled in the boss outer rim.
2. the barrier package bag according to claim 1 available for subsidiary infusion bag inner chamber temperature, it is characterised in that Location sealing block (3) is provided with the sealed frame (11), when the connecting tube (21) inserts chamber resettling (12), in institute State the outer wall of insertion end (211) described in location sealing block (3) sealed envelope described in sealed frame (11).
3. the barrier package bag according to claim 1 available for subsidiary infusion bag inner chamber temperature, it is characterised in that Several sealing and reinforcing blocks (4) are provided with the sealed frame (11).
4. the barrier package bag according to claim 1 available for subsidiary infusion bag inner chamber temperature, it is characterised in that The profile of the packaging bag body (1) is rectangle.
CN201720749500.4U 2017-06-26 2017-06-26 Barrier package bag available for subsidiary infusion bag inner chamber temperature Active CN207046017U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201720749500.4U CN207046017U (en) 2017-06-26 2017-06-26 Barrier package bag available for subsidiary infusion bag inner chamber temperature

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201720749500.4U CN207046017U (en) 2017-06-26 2017-06-26 Barrier package bag available for subsidiary infusion bag inner chamber temperature

Publications (1)

Publication Number Publication Date
CN207046017U true CN207046017U (en) 2018-02-27

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CN201720749500.4U Active CN207046017U (en) 2017-06-26 2017-06-26 Barrier package bag available for subsidiary infusion bag inner chamber temperature

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108904274A (en) * 2018-07-16 2018-11-30 石家庄四药有限公司 A kind of double-layer sterile soft bag infusion sterilizing temperature control device and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108904274A (en) * 2018-07-16 2018-11-30 石家庄四药有限公司 A kind of double-layer sterile soft bag infusion sterilizing temperature control device and preparation method thereof

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