CN207020194U - A kind of expression detection kits of PD 1 - Google Patents

A kind of expression detection kits of PD 1 Download PDF

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Publication number
CN207020194U
CN207020194U CN201720894263.0U CN201720894263U CN207020194U CN 207020194 U CN207020194 U CN 207020194U CN 201720894263 U CN201720894263 U CN 201720894263U CN 207020194 U CN207020194 U CN 207020194U
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China
Prior art keywords
box body
thread segment
rotary shaft
lid
plate
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CN201720894263.0U
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Chinese (zh)
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张道允
巩子英
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Jiaxing Permitted Medical Inspection Co Ltd
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Jiaxing Permitted Medical Inspection Co Ltd
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Abstract

The utility model discloses a kind of expression detection kits of PD 1,Including box body,Lid is provided with the top of the box body,Lid inwall is provided with pressing plate,The box body intracavity bottom is provided with rotary shaft,The part that rotary shaft is located in box body is provided with the first thread segment and the second thread segment,Inner thread sleeve with matching is arranged with outside first thread segment and the second thread segment,Inner thread sleeve upper articulation has connecting rod,The connecting rod other end is hinged with supporting plate bottom,Box body inner chamber top, which is provided with, places plate,Place plate and be provided with through hole,Arc and second spring are provided with through hole,The utility model is provided with rotary shaft,First thread segment,Second thread segment,Inner thread sleeve and connecting rod,By coordinating adjustment supporting plate with placing the distance between plate with upper-part,To adapt to the Reagent Tube of different length,Provided with the first spring and pressing plate,The lid of Reagent Tube is compressed,Avoid causing the lid of Reagent Tube to come off because rocking,Reagent in Reagent Tube spills,Mutually pollution.

Description

A kind of PD-1 expressions detection kit
Technical field
A kind of kit is the utility model is related to, specifically a kind of PD-1 expressions detection kit.
Background technology
PD-1 (programmed death 1) programmed death acceptor 1, initially in the mouse Tcell hybridoma of apoptosis It is a kind of I type transmembrane glycopeptide by being positioned at chromosome 2q37.3 PD-1 gene codes it was found that belonging to CD28 superfamily members In vain.PD-1 is mainly expressed in the T cell, B cell and active antigen presenting cells of activation(It is thin including monocyte and dendron shape Born of the same parents).PD-1 parts mainly have PD-L1 and PD-L2, and both can have found there is height in some tumour cells in correlative study Expression.Existing PD-1 expressions detection kit typically only possesses the function of storage, in transport and handling process, reagent Tube capacity is easily rocked or toppled over, and both pollutes kit, have impact on the detection of reagent again, and fixed effect is poor, it is difficult to which Reagent Tube is entered The rational protection of row.
Utility model content
The purpose of this utility model is to provide a kind of PD-1 expressions detection kit, to solve above-mentioned background technology The problem of middle proposition.
To achieve the above object, the utility model provides following technical scheme:
A kind of PD-1 expressions detection kit, including box body, lid and rotary shaft, the box body top are provided with box Lid, lid both sides inwall offer the first chute, the first sliding block are slidably connected in the first chute, and the first sliding block is fixed on pressing plate Both ends, the box body intracavity bottom are provided with rotary shaft, and rotary shaft is rotatablely connected with box body, and rotary shaft right-hand member runs through box body right side wall And box portion outside is extended to, the part that rotary shaft is located in box body is provided with the first thread segment and the second thread segment, the first thread segment Thread rotary orientation with the second thread segment is on the contrary, be arranged with interior spiral shell with matching outside the first thread segment and the second thread segment Line sleeve, inner thread sleeve upper articulation have connecting rod, and the connecting rod other end is hinged with supporting plate bottom, and supporting plate is slided with inboard wall of cartridge Dynamic connection, supporting plate both ends are provided with the second sliding block, offer the second chute with the cooperation of the second sliding block on inboard wall of cartridge, in box body Chamber top, which is provided with, places plate, places plate and is provided with through hole, through hole totally eight, is provided with arc in through hole, in arc and through hole Second spring is connected between wall.
As further program of the utility model:The first bullet is connected between the pressing plate top and lid inner cavity top Spring.
As further program of the utility model:The rotary shaft right-hand member is fixed with rotational handle.
As further program of the utility model:First thread segment is located on the left of the second thread segment.
As further program of the utility model:The supporting plate top is provided with spongy layer.
As further program of the utility model:The arc two pieces and is symmetrical arranged totally.
Compared with prior art, the beneficial effects of the utility model are:The utility model is provided with rotary shaft, the first screw thread Section, the second thread segment, inner thread sleeve and connecting rod, by coordinating adjustment supporting plate with placing the distance between plate with upper-part, To adapt to the Reagent Tube of different length, provided with arc and second spring, second spring and arc can be consolidated to Reagent Tube Determine and there is buffering effect, and can adapt to the Reagent Tube of diameter, provided with the first spring and pressing plate, by the lid pressure of Reagent Tube Tightly, avoid causing the lid of Reagent Tube to come off because rocking, the reagent in Reagent Tube spills, mutually pollution.
Brief description of the drawings
Fig. 1 is the structural representation of PD-1 expression detection kits.
Fig. 2 is the structural representation that plate is placed in PD-1 expression detection kits.
In figure:1- box bodys, 2- Reagent Tubes, 3- place plate, the sliding blocks of 4- first, the chutes of 5- first, 6- pressing plates, the bullets of 7- first Spring, 8- lids, the chutes of 9- second, the sliding blocks of 10- second, 11- supporting plates, 12- connecting rods, the thread segments of 13- first, 14- inner screw sheaths Cylinder, 15- rotary shafts, the thread segments of 16- second, 17- spongy layers, 18- rotational handles, 19- through holes, 20- second springs, 21- arcs Plate.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the embodiment of the utility model is carried out Clearly and completely describing, it is clear that described embodiment is only the utility model part of the embodiment, rather than whole Embodiment.Based on the embodiment in the utility model, those of ordinary skill in the art are not under the premise of creative work is made The every other embodiment obtained, belong to the scope of the utility model protection.
Refer to Fig. 1~2, in the utility model embodiment, a kind of PD-1 expressions detection kit, including box body 1, Lid 8 and rotary shaft 15, the top of box body 1 are provided with lid 8, and the both sides inwall of lid 8 offers the first chute 5, the first chute 5 The first sliding block 4 is inside slidably connected, the first sliding block 4 is fixed on the both ends of pressing plate 6, connected between the top of pressing plate 6 and the inner cavity top of lid 8 The first spring 7 is connected to, the intracavity bottom of box body 1 is provided with rotary shaft 15, and rotary shaft 15 is rotatablely connected with box body 1, rotary shaft 15 Right-hand member is through the right side wall of box body 1 and extends to outside box body 1, and the right-hand member of rotary shaft 15 is fixed with rotational handle 18, rotary shaft 15 The first thread segment 13 and the second thread segment 16 are provided with the part in box body 1, it is left that the first thread segment 13 is located at the second thread segment 16 The thread rotary orientation of side, the first thread segment 13 and the second thread segment 16 is on the contrary, the first thread segment 13 and the outside of the second thread segment 16 are equal Inner thread sleeve 14 with matching is arranged with, the upper articulation of inner thread sleeve 14 has connecting rod 12, the other end of connecting rod 12 and branch The bottom of fagging 11 is hinged, and supporting plate 11 is slidably connected with the inwall of box body 1, and the both ends of supporting plate 11 are provided with the second sliding block 10, in box body 1 The second chute 9 coordinated with the second sliding block 10 is offered on wall, the top of supporting plate 11 is provided with spongy layer 17, rotates rotational handle 18, rotational handle 18 drives rotary shaft 15 to rotate, and rotary shaft 15 drives the first thread segment 13 and the second thread segment 16 to rotate, and first The inner thread sleeve 14 that the thread segment 16 of thread segment 13 and second drives it outside respectively moves, the drivening rod 12 of inner thread sleeve 14 Motion, connecting rod 12 drives supporting plate 11 to be moved upwardly or downwardly, so as to adjust the height of supporting plate 11, to adapt to different length Reagent Tube 2, the Reagent Tube 2 of different length can be placed, the inner chamber top of box body 1, which is provided with, places plate 3, places plate 3 and is provided with through hole 19, through hole 19 totally eight is provided with arc 21 in through hole 19, and arc 21 two pieces and is symmetrical arranged, arc 21 and through hole totally Second spring 20 is connected between 19 inwalls, by region of the Reagent Tube 2 through two pieces of arcs 21, passes through second spring 20 Reagent Tube 2 can be fixed and there is buffering effect, and can adapt to the Reagent Tube 2 of diameter.
Operation principle of the present utility model is:The utility model when in use, first according to the length adjustment branch of Reagent Tube 2 Fagging 11 is with placing the distance between plate 3, to adapt to the Reagent Tube 2 of different length, is specially:Rotational handle 18 is rotated, is rotated Axle handle 18 drives rotary shaft 15 to rotate, and rotary shaft 15 drives the first thread segment 13 and the second thread segment 16 to rotate, the first screw thread The inner thread sleeve 14 that the thread segment 16 of section 13 and second drives it outside respectively is moved, and the drivening rod 12 of inner thread sleeve 14 is transported Dynamic, connecting rod 12 drives supporting plate 11 to be moved upwardly or downwardly, so as to adjust the height of supporting plate 11, to adapt to the examination of different length Agent pipe 2, the Reagent Tube 2 of different length can be placed, then the region by Reagent Tube 2 through two pieces of arcs 21, reagent The bottom of pipe 2 contacts with spongy layer 17, Reagent Tube 2 can be fixed by second spring 20 and have buffering effect, and can The Reagent Tube 2 of diameter is adapted to, then covers lid 8, the pressing plate 6 in lid 8 compresses the lid of Reagent Tube 2, avoids because rocking The lid of Reagent Tube 2 is caused to come off, the reagent in Reagent Tube 2 spills, mutually pollution.
It is obvious to a person skilled in the art that the utility model is not limited to the details of above-mentioned one exemplary embodiment, and And in the case of without departing substantially from spirit or essential attributes of the present utility model, it can realize that this practicality is new in other specific forms Type.Therefore, no matter from the point of view of which point, embodiment all should be regarded as exemplary, and is nonrestrictive, this practicality is new The scope of type limits by appended claims rather than described above, it is intended that the equivalency fallen in claim is contained All changes in justice and scope are included in the utility model.Any reference in claim should not be considered as limitation Involved claim.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment is only wrapped Containing an independent technical scheme, this narrating mode of specification is only that those skilled in the art should for clarity Using specification as an entirety, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art It is appreciated that other embodiment.

Claims (6)

1. a kind of PD-1 expressions detection kit, including box body(1), lid(8)And rotary shaft(15), it is characterised in that The box body(1)Top is provided with lid(8), lid(8)Both sides inwall offers the first chute(5), the first chute(5)Interior slip It is connected with the first sliding block(4), the first sliding block(4)It is fixed on pressing plate(6)Both ends, the box body(1)Intracavity bottom is provided with rotary shaft (15), rotary shaft(15)With box body(1)Rotation connection, rotary shaft(15)Right-hand member runs through box body(1)Right side wall simultaneously extends to box body (1)Outside, rotary shaft(15)Positioned at box body(1)Interior part is provided with the first thread segment(13)With the second thread segment(16), first Thread segment(13)With the second thread segment(16)Thread rotary orientation on the contrary, the first thread segment(13)With the second thread segment(16)It is outside equal It is arranged with inner thread sleeve with matching(14), inner thread sleeve(14)Upper articulation has connecting rod(12), connecting rod(12)Separately One end and supporting plate(11)Bottom is hinged, supporting plate(11)With box body(1)Inwall is slidably connected, supporting plate(11)Both ends are provided with the Two sliding blocks(10), box body(1)Offered on inwall and the second sliding block(10)The second chute coordinated(9), box body(1)Inner chamber top Provided with placement plate(3), place plate(3)It is provided with through hole(19), through hole(19)Totally eight, through hole(19)It is interior to be provided with arc (21), arc(21)With through hole(19)Second spring is connected between inwall(20).
2. PD-1 expressions detection kit according to claim 1, it is characterised in that the pressing plate(6)Top with Lid(8)The first spring is connected between inner cavity top(7).
3. PD-1 expressions detection kit according to claim 1, it is characterised in that the rotary shaft(15)Right-hand member It is fixed with rotational handle(18).
4. PD-1 expressions detection kit according to claim 1, it is characterised in that first thread segment(13) Positioned at the second thread segment(16)Left side.
5. PD-1 expressions detection kit according to claim 1, it is characterised in that the supporting plate(11)Top Provided with spongy layer(17).
6. PD-1 expressions detection kit according to claim 1, it is characterised in that the arc(21)Totally two Block and it is symmetrical arranged.
CN201720894263.0U 2017-07-23 2017-07-23 A kind of expression detection kits of PD 1 Active CN207020194U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201720894263.0U CN207020194U (en) 2017-07-23 2017-07-23 A kind of expression detection kits of PD 1

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201720894263.0U CN207020194U (en) 2017-07-23 2017-07-23 A kind of expression detection kits of PD 1

Publications (1)

Publication Number Publication Date
CN207020194U true CN207020194U (en) 2018-02-16

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CN201720894263.0U Active CN207020194U (en) 2017-07-23 2017-07-23 A kind of expression detection kits of PD 1

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108814546A (en) * 2018-03-14 2018-11-16 天津中医药大学 A kind of Chinese medicine inspection tongue diagnosing instrument
CN108837857A (en) * 2018-06-22 2018-11-20 朱晓明 A kind of blood testing test tube rack
CN108860955A (en) * 2018-04-23 2018-11-23 杨久峰 A kind of environment soil samples and detecting assay kit
CN112550920A (en) * 2020-12-29 2021-03-26 深圳容金科技有限公司 Chloramphenicol detection kit

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108814546A (en) * 2018-03-14 2018-11-16 天津中医药大学 A kind of Chinese medicine inspection tongue diagnosing instrument
CN108860955A (en) * 2018-04-23 2018-11-23 杨久峰 A kind of environment soil samples and detecting assay kit
CN108860955B (en) * 2018-04-23 2019-09-27 广西景秀环保科技有限公司 A kind of environment soil samples and detecting assay kit
CN108837857A (en) * 2018-06-22 2018-11-20 朱晓明 A kind of blood testing test tube rack
CN112550920A (en) * 2020-12-29 2021-03-26 深圳容金科技有限公司 Chloramphenicol detection kit

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