CN207016784U - A kind of environmental control system - Google Patents

A kind of environmental control system Download PDF

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Publication number
CN207016784U
CN207016784U CN201720947076.4U CN201720947076U CN207016784U CN 207016784 U CN207016784 U CN 207016784U CN 201720947076 U CN201720947076 U CN 201720947076U CN 207016784 U CN207016784 U CN 207016784U
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China
Prior art keywords
chamber
blower fan
exhausting device
gas outlet
air
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Application number
CN201720947076.4U
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Chinese (zh)
Inventor
王铸海
叶慧
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Pilot medical technology (Shenzhen) Co.,Ltd.
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Huadong Medicine (hangzhou) Gene Science And Technology Co Ltd
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Abstract

The utility model discloses a kind of environmental control system, and for the anti-pollution of automatic drop digital pcr system, the environmental control system includes first chamber, second chamber, lifting isolating door, second chamber air exhausting device and filtering air exhausting device;The first chamber and second chamber are separated by lifting isolating door;The gas outlet of second chamber is connected with the air inlet of second chamber air exhausting device, and the gas outlet of the first chamber and the gas outlet of second chamber air exhausting device are connected with filtering the air inlet of air exhausting device, and the gas outlet for filtering air exhausting device communicates with air.The utility model is by adjusting second chamber air exhausting device, filtering air exhausting device and the folding for lifting isolating door, it ensure that gas flow filtering air exhausting device or second chamber in first chamber, gas only flows to filtering air exhausting device in second chamber, first chamber and second chamber share a filtering air exhausting device, realization automatically controls air flow in each region, so as to control the final whereabouts of pollutant.

Description

A kind of environmental control system
Technical field
The utility model belongs to PCR fields, and in particular to a kind of anti-pollution dress for automatic drop digital pcr system Put.
Background technology
PCR reaction maximum feature be that there is larger amplification ability and high sensitivity, but it is troubling the problem of be Easily pollution, extremely micro pollution can cause the generation of false positive.Digital pcr (Digital PCR, dPCR) is that one kind is based on Single-molecule PCR method is a kind of method of absolute quantitation come the nucleic acid quantification method counted.Relatively common PCR and fluorescence For quantitative PCR (Fluorescence Quantitative Polymerase Chain Reaction, qPCR), digital pcr System relates generally to multiple necessary instruments, it is necessary to which multistep shifts the operation of sample, thus considerably increases the possibility of sample contamination Property.Especially automatic drop digital pcr system, due to equipment collection such as nucleic acid extraction, drop sample-adding, PCR amplifications, read modules Close in a system, the initial data extraction of sample is realized in automation, expands the cross pollution situation between each module.Mesh Method as previous all using physical barriers carries out contamination control, but is limited by the device space and operation possibility, it is difficult to Carry out Aerosol Pollution in complete physical barriers, particularly PCR amplification procedures.
Utility model content
For above-mentioned deficiency, the utility model provides a kind of environmental control system, for the anti-of automatic drop digital pcr system Pollution, it is intended to provide a kind of gas flow for each intermodule in automatic drop digital pcr system, make pollutant toward specific side To flowing, prevent the pathogenic microorganisms in air and pollutant from being had an impact to experimental result.
In order to achieve the above object, technical scheme is as follows used by the utility model:A kind of environmental control system, for certainly Hydrodynamic drips the anti-pollution of digital pcr system, and the environmental control system includes first chamber, second chamber, lifting isolating door, second Chamber air exhausting device and filtering air exhausting device;The first chamber and second chamber are separated by lifting isolating door;Second chamber Gas outlet be connected with the air inlet of second chamber air exhausting device, the gas outlet of the first chamber and second chamber air draft dress The gas outlet put is connected with filtering the air inlet of air exhausting device, and the gas outlet for filtering air exhausting device communicates with air.
Preferably, the automatic drop digital pcr system includes nucleic acid extraction module, drop sample-adding module, PCR amplifications Module, biochip read module.
Preferably, the nucleic acid extraction module and drop sample-adding module are arranged in first chamber, the PCR expands mould Block and biochip read module are arranged in second chamber.
Preferably, the second chamber air exhausting device includes the first blower fan and the second blower fan, first blower fan goes out Gas port is connected with filtering the air inlet of air exhausting device;The air inlet of second blower fan is connected with second chamber, the second wind The gas outlet of machine is connected with filtering the air inlet of air exhausting device.
Preferably, the air inlet of first blower fan is connected with PCR amplifications module.
Preferably, the second chamber air exhausting device includes the first blower fan and the second blower fan, first blower fan goes out Gas port is connected with the air inlet of the second blower fan, and the second chamber is connected with the air inlet of the second blower fan, the second blower fan Gas outlet is connected with filtering the air inlet of air exhausting device.
Preferably, the air inlet of first blower fan is connected with PCR amplifications module.
Preferably, the filtering air exhausting device includes the 3rd blower fan and high efficiency particulate air filter, the outlet of the first chamber Mouthful and air inlet of the gas outlet with the 3rd blower fan of second chamber air exhausting device be connected, the gas outlet of the 3rd blower fan with it is efficient The air inlet of filter is connected, and the gas outlet of high efficiency particulate air filter communicates with air.
Preferably, the filtering air exhausting device includes the 3rd blower fan and high efficiency particulate air filter, the outlet of the first chamber Mouthful and the gas outlet of second chamber air exhausting device be connected with the air inlet of high efficiency particulate air filter, the gas outlet of high efficiency particulate air filter and The air inlet of 3rd blower fan is connected, and the gas outlet of the 3rd blower fan communicates with air.
The beneficial effects of the utility model are as follows:When lifting isolating door closing, gas passes through the 3rd wind in first chamber Machine is discharged after entering high efficiency particulate air filter by air outlet;When lifting isolating door opening, the second blower fan makes the air-flow of first chamber All the time flow to second chamber and entered by the 3rd blower fan after high efficiency particulate air filter and discharged by air outlet;
In second chamber PCR amplification module one the first blower fan of additional, make PCR amplification module above air-flow not Flow into second chamber, filtering air exhausting device is directly entered by gas channel, then by the effect of the 3rd blower fan, through too high Discharged after effect filter by air outlet;
The utility model controls the gas flow in each chamber, so as to control dirt by the rotating speed of three blower fans of regulation Contaminate the final whereabouts of thing.
Brief description of the drawings
Fig. 1 is the structural representation of the utility model embodiment 1;
Fig. 2 is the structural representation of the utility model embodiment 2;
Fig. 3 is the structural representation of the utility model embodiment 3;
Fig. 4 is the structural representation of the utility model embodiment 4;
In figure:Nucleic acid extraction module 1, drop sample-adding module 2, PCR amplifications module 3, biochip read module 4, first Chamber 5, second chamber 6, high efficiency particulate air filter 7, lifting isolating door 8, the first blower fan 9, gas channel 10, the second blower fan the 11, the 3rd Blower fan 12, plenum chamber 13.
Embodiment
The utility model is described further below in conjunction with the accompanying drawings.
As Figure 1-4, a kind of environmental control system provided by the utility model, for automatic drop digital pcr system Anti-pollution, the automatic drop digital pcr system includes nucleic acid extraction module 1, drop sample-adding module 2, PCR amplifications module 3, life Thing chip read module 4.The environmental control system includes first chamber 5, second chamber 6, lifting isolating door 8, second chamber row Wind apparatus and filtering air exhausting device;The first chamber 5 and second chamber 6 are separated by lifting isolating door 8;The nucleic acid extraction Module 1 and drop sample-adding module 2 are arranged on 5 in first chamber, and the PCR amplification modules 3 and biochip read module 4 are set 6 in second chamber.The gas outlet of second chamber 6 is connected with the air inlet of second chamber air exhausting device, the first chamber 5 Gas outlet and second chamber air exhausting device gas outlet with filter air exhausting device air inlet be connected, filter air exhausting device Gas outlet communicated with air.
Embodiment 1:
As shown in figure 1, the second chamber air exhausting device includes the first blower fan 9 and the second blower fan 11;The filtering air draft Device includes the 3rd blower fan 12 and high efficiency particulate air filter 7;The gas outlet of the first chamber 5, the gas outlet of the first blower fan 9 and The gas outlet of two blower fans 11 is connected by gas channel 10 with the air inlet of the 3rd blower fan 12;First blower fan 9 enters Air port is connected with PCR amplifications module 3, and the air inlet of second blower fan 11 is connected with second chamber 6, and the 3rd blower fan 12 goes out Gas port is connected with the air inlet of plenum chamber 13, and high efficiency particulate air filter 7 is arranged on the exit of plenum chamber 13, high efficiency particulate air filter 7 Air inlet is connected with plenum chamber 13, and the gas outlet of high efficiency particulate air filter 7 communicates with air.
Embodiment 2:
As shown in Fig. 2 the second chamber air exhausting device includes the first blower fan 9 and the second blower fan 11;The filtering air draft Device includes the 3rd blower fan 12 and high efficiency particulate air filter 7;The gas outlet of first blower fan 9 is connected with the air inlet of the second blower fan 11 Logical, the second chamber 6 is connected with the air inlet of the second blower fan 11, air inlet and the PCR amplification modules of first blower fan 9 3 are connected;The gas outlet of the first chamber 5 and the gas outlet of the second blower fan 11 pass through the blower fan 12 of gas channel 10 and the 3rd Air inlet is connected, and the gas outlet of the 3rd blower fan 12 is connected with the air inlet of plenum chamber 13, and high efficiency particulate air filter 7 is arranged on static pressure The exit of room 13, the air inlet of high efficiency particulate air filter 7 are connected with plenum chamber 13, the gas outlet of high efficiency particulate air filter 7 and big gas phase It is logical.
Embodiment 3:
The second chamber air exhausting device includes the first blower fan 9 and the second blower fan 11;The filtering air exhausting device includes the Three blower fans 12 and high efficiency particulate air filter 7;The air inlet of first blower fan 9 is connected with PCR amplifications module 3, second blower fan 11 Air inlet be connected with second chamber 6, the gas outlet of the first chamber 5, the gas outlet and second of first blower fan 9 The gas outlet of blower fan 11 is connected by gas channel 10 with the air inlet of plenum chamber 13, and high efficiency particulate air filter 7 is arranged on static pressure The exit of room 13, the air inlet of high efficiency particulate air filter 7 are connected with plenum chamber 13, the gas outlet of high efficiency particulate air filter 7 and the 3rd wind The air inlet of machine 12 is connected, and the gas outlet of the 3rd blower fan 12 communicates with air.
Embodiment 4:
As shown in figure 4, the second chamber air exhausting device includes the first blower fan 9 and the second blower fan 11;The filtering air draft Device includes the 3rd blower fan 12 and high efficiency particulate air filter 7;The air inlet of first blower fan 9 is connected with PCR amplifications module 3, described The gas outlet of first blower fan 9 is connected with the air inlet of the second blower fan 11, the air inlet of the blower fan 11 of second chamber 6 and second It is connected, the gas outlet of the gas outlet of first chamber 5 and the second blower fan 11 passes through the air inlet of gas channel 10 and plenum chamber 13 Mouth is connected, and high efficiency particulate air filter 7 is arranged on the exit of plenum chamber 13, and the air inlet of high efficiency particulate air filter 7 is connected with plenum chamber 13 Logical, the gas outlet of high efficiency particulate air filter 7 is connected with the air inlet of the 3rd blower fan 12, gas outlet and the big gas phase of the 3rd blower fan 12 It is logical.
There is alarm on high efficiency particulate air filter 14, after performance can not meet requirement, remind user to be changed. The air quantity of each blower fan is adjustable, and the first blower fan 9, the second blower fan 11 and the 3rd blower fan 12 can use model 9TG24P0G01 blower fan, but not limited to this.
The course of work of the present utility model is as follows:
1st, when lifting the closing of isolating door 8, the second blower fan 11 and control first chamber 5 of control second chamber 6 are opened 3rd blower fan 12, now nucleic acid extraction module 1 and drop sample-adding module 2 are working;Nucleic acid extraction module 1 and drop sample-adding module 2 end-of-jobs, it is then turned on the first blower fan 9;3rd blower fan 12 extracts the gas in gas channel 10 and gas is entered plenum chamber 13, the gas in plenum chamber 13 is arranged to outdoor after being filtered by high efficiency particulate air filter 7 through exhaust outlet;In the process, first is adjusted The rotating speed of blower fan 9, the second blower fan 11 and the 3rd blower fan 12 so that the pressure in first chamber 5 is more than the pressure in gas channel 10 Power, the pressure in second chamber 6 are more than the pressure in gas channel 10.
2nd, when lifting the opening of isolating door 8, the biological specimen of first chamber 6 is transferred in PCR amplification modules 3, now, Adjust the rotating speed of the first blower fan 9, the second blower fan 11 and the 3rd blower fan 12 so that the pressure in first chamber 5 is more than second chamber 6 Interior pressure, the pressure in second chamber 6 are more than the pressure in gas channel 10 so that first chamber 5 and second chamber 6 combine The gas in face flows from first chamber 5 to the direction of second chamber 6 all the time;
3rd, the lifting isolating door 8 of first chamber 5 and the junction of second chamber 6 is closed, PCR amplifications module 3 is started working, controlled The air quantity of second blower fan 10 of second chamber 6 processed is reduced, and only meets that outside air flows into second chamber 6;
4th, when PCR expands 3 end-of-job of module, then it is delayed a period of time, closes the first blower fan 9;
5th, the biological specimen of second chamber 6 is transferred on biochip read module 4, biochip read module 4 is opened Beginning work;
6th, during 4 end-of-job of biochip read module, then it is delayed a period of time, closes the second blower fan 11, closes the 3rd Blower fan 12.

Claims (9)

  1. A kind of 1. environmental control system, for the anti-pollution of automatic drop digital pcr system, it is characterised in that the anti-pollution dress Put including first chamber, second chamber, lifting isolating door, second chamber air exhausting device and filtering air exhausting device;First chamber Room and second chamber are separated by lifting isolating door;The gas outlet of second chamber is connected with the air inlet of second chamber air exhausting device Logical, the gas outlet of the first chamber and the gas outlet of second chamber air exhausting device are connected with filtering the air inlet of air exhausting device Logical, the gas outlet for filtering air exhausting device communicates with air.
  2. A kind of 2. environmental control system according to claim 1, it is characterised in that the automatic drop digital pcr system bag Include nucleic acid extraction module, drop sample-adding module, PCR amplifications module, biochip read module.
  3. 3. a kind of environmental control system according to claim 2, it is characterised in that the nucleic acid extraction module and drop sample-adding Module is arranged in first chamber, and the PCR amplification modules and biochip read module are arranged in second chamber.
  4. A kind of 4. environmental control system according to Claims 2 or 3, it is characterised in that the second chamber air exhausting device bag The first blower fan and the second blower fan are included, the gas outlet of first blower fan is connected with filtering the air inlet of air exhausting device;Described The air inlet of two blower fans is connected with second chamber, and the gas outlet of the second blower fan is connected with filtering the air inlet of air exhausting device.
  5. 5. a kind of environmental control system according to claim 4, it is characterised in that the air inlet and PCR of first blower fan Amplification module is connected.
  6. A kind of 6. environmental control system according to Claims 2 or 3, it is characterised in that the second chamber air exhausting device bag The first blower fan and the second blower fan are included, the gas outlet of first blower fan is connected with the air inlet of the second blower fan, second chamber Room is connected with the air inlet of the second blower fan, and the gas outlet of the second blower fan is connected with filtering the air inlet of air exhausting device.
  7. 7. a kind of environmental control system according to claim 6, it is characterised in that the air inlet and PCR of first blower fan Amplification module is connected.
  8. 8. a kind of environmental control system according to claim 1, it is characterised in that the filtering air exhausting device includes the 3rd wind Machine and high efficiency particulate air filter, the gas outlet of the first chamber and the gas outlet of second chamber air exhausting device are entered with the 3rd blower fan Gas port is connected, and the gas outlet of the 3rd blower fan is connected with the air inlet of high efficiency particulate air filter, the gas outlet of high efficiency particulate air filter with it is big Gas phase is led to.
  9. 9. a kind of environmental control system according to claim 1, it is characterised in that the filtering air exhausting device includes the 3rd wind Machine and high efficiency particulate air filter, the gas outlet of the first chamber and the gas outlet of second chamber air exhausting device with high efficiency particulate air filter Air inlet is connected, and the gas outlet of high efficiency particulate air filter is connected with the air inlet of the 3rd blower fan, the gas outlet of the 3rd blower fan with it is big Gas phase is led to.
CN201720947076.4U 2017-07-31 2017-07-31 A kind of environmental control system Active CN207016784U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201720947076.4U CN207016784U (en) 2017-07-31 2017-07-31 A kind of environmental control system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201720947076.4U CN207016784U (en) 2017-07-31 2017-07-31 A kind of environmental control system

Publications (1)

Publication Number Publication Date
CN207016784U true CN207016784U (en) 2018-02-16

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ID=61482494

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201720947076.4U Active CN207016784U (en) 2017-07-31 2017-07-31 A kind of environmental control system

Country Status (1)

Country Link
CN (1) CN207016784U (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113214982A (en) * 2021-06-09 2021-08-06 北京卓诚惠生生物科技股份有限公司 PCR chamber
CN113388507A (en) * 2021-06-09 2021-09-14 北京卓诚惠生生物科技股份有限公司 Nucleic acid extraction and PCR detection all-in-one machine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113214982A (en) * 2021-06-09 2021-08-06 北京卓诚惠生生物科技股份有限公司 PCR chamber
CN113388507A (en) * 2021-06-09 2021-09-14 北京卓诚惠生生物科技股份有限公司 Nucleic acid extraction and PCR detection all-in-one machine
CN113214982B (en) * 2021-06-09 2021-11-26 北京卓诚惠生生物科技股份有限公司 PCR chamber

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GR01 Patent grant
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CP01 Change in the name or title of a patent holder
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Address after: Room 1114, No. 341, Jin Jun Road, Jianggan District, Jianggan District, Hangzhou, Zhejiang

Patentee after: Navigation gene technology (Hangzhou) Co., Ltd.

Address before: Room 1114, No. 341, Jin Jun Road, Jianggan District, Jianggan District, Hangzhou, Zhejiang

Patentee before: Huadong medicine (Hangzhou) gene science and Technology Co Ltd

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20211214

Address after: 518000 g1316, Lianxing building, building B, Yihua new village, district 46, Haifu community, Xin'an street, Bao'an District, Shenzhen, Guangdong Province

Patentee after: Pilot medical technology (Shenzhen) Co.,Ltd.

Address before: Room 1114, Jinjun building, 341 Shuixiang Road, Jianggan District, Hangzhou City, Zhejiang Province, 310020

Patentee before: PILOT GENE TECHNOLOGIES (HANGZHOU) Co.,Ltd.