CN206984712U - A kind of novel medicinal bottle stopper for lyophilized powder formulation - Google Patents

A kind of novel medicinal bottle stopper for lyophilized powder formulation Download PDF

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Publication number
CN206984712U
CN206984712U CN201720732088.5U CN201720732088U CN206984712U CN 206984712 U CN206984712 U CN 206984712U CN 201720732088 U CN201720732088 U CN 201720732088U CN 206984712 U CN206984712 U CN 206984712U
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China
Prior art keywords
cock body
groove
air channel
bottle stopper
lyophilized powder
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CN201720732088.5U
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Chinese (zh)
Inventor
夏汉桥
张雾云
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YINGCHENG HENGTIAN PHARMACEUTICAL PACKAGING CO Ltd
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YINGCHENG HENGTIAN PHARMACEUTICAL PACKAGING CO Ltd
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Abstract

It the utility model is related to a kind of novel medicinal bottle stopper for lyophilized powder formulation, the cock body being connected including lid and with the lid, the center bottom of the cock body from the lid extends vertically, the center bottom of the cock body is provided inwardly with the groove of circle, the peripheral edge of the groove to the cock body is provided with an air channel connected with the groove, the air channel upwardly extends from the bottom of the cock body, and the depth of the air channel is small compared with the depth of the groove, the cock body is tangent in two sides where the air channel and the groove.The novel medicinal bottle stopper for lyophilized powder formulation is simple in construction, easy to use, it can make medicine bottle that there is good air-tightness, have in freeze drying powder injection production and packaging process effect it is good, on engine efficiency it is high the advantages of, be advantageous to the fast vacuum aseptic packaging of medicine, improve product quality and efficiency.

Description

A kind of novel medicinal bottle stopper for lyophilized powder formulation
Technical field
It the utility model is related to a kind of bottle stopper, more particularly to a kind of novel medicinal bottle stopper for lyophilized powder formulation.
Background technology
Existing injection and powder medicine are typically using bottled, and especially freeze drying powder injection is typically according to national medical product Standard is preserved all using bottled using rubber bottle cap sealing.The production of freeze drying powder injection be usually will contain medicine effectively into The decoction divided carries out sterile vacuum packaging after freezing, and its production process is typically very long.Production process is as follows:Cool 2 hours first, Temperature is down to -40 DEG C, maintains this temperature about 6 hours;Start progressively to be warming up to 25 DEG C, require vacuum state during this, keep Vacuum 30-35Pa or so, about 48 hours need to be taken;Terminate to freeze, gland, pack to obtain finished product.Should be by medicine in freeze-drying process On bottle cap, keep sterile, prevent bottle cap too tight from what is covered again, in order to avoid the moisture in decoction can not evaporate rapidly, influence The lyophilized time.This require bottle cap should air-tightness it is good, meet that effect is good, upper engine efficiency is high again, be advantageous to medicine Sterile vacuum packaging.Existing medicinal bottle cap is relatively simple for structure, as shown in Figure 1 typically common one-shot forming knot Structure, it has the advantages of air-tightness is good, but it is good and true it is impossible to meet the effect required by freeze drying powder injection production The condition of empty quick aseptic packaging.Therefore a kind of new medicinal bottle cap is invented, to meet that the requirement of freeze drying powder injection production is non- Chang Youyi.
Utility model content
The purpose of this utility model is to be directed to above-mentioned present situation, there is provided one kind makes medicine bottle have air-tightness good and effect Good novel medicinal bottle stopper for lyophilized powder formulation.
The technical solution adopted in the utility model:A kind of novel medicinal bottle stopper for lyophilized powder formulation, including lid and with the lid connect The cock body connect, the center bottom of the cock body from the lid extend vertically, and the center bottom of the cock body is provided inwardly with circle Groove, the internal diameter of the groove accounts for the 20%-30% of the cock body external diameter, and the peripheral edge of the groove to the cock body is opened There is an air channel connected with the groove, the air channel upwardly extends from the bottom of the cock body, and the air channel Depth it is small compared with the depth of the groove, the cock body is tangent in two sides where the air channel and the groove, and institute Circular arc where stating the external margin of air channel accounts for the 15%-30% of cock body periphery circular arc.
Effect of the present utility model is:The novel medicinal bottle stopper for lyophilized powder formulation is simple in construction, easy to use, can have medicine bottle Good air-tightness, freeze drying powder injection production and packaging process in have effect it is good, on engine efficiency it is high the advantages of, favorably In the fast vacuum aseptic packaging of medicine, product quality and efficiency are improved.
Further, the lid and cock body are quality of rubber materials.
Further, the outer wall of the cock body is provided with some double wedges.
Further, the bottom margin of the cock body is provided with 3 ° of guide angles.
Further, the internal diameter of the groove accounts for the 25% of the cock body external diameter.
Further, the circular arc where the external margin of the air channel accounts for the 20% of cock body periphery circular arc.
Brief description of the drawings
Fig. 1 is a kind of dimensional structure diagram of novel medicinal bottle stopper for lyophilized powder formulation provided by the utility model.
Embodiment
Principle of the present utility model and feature are described below in conjunction with accompanying drawing, example is served only for explaining this practicality It is new, it is not intended to limit the scope of the utility model.
Referring to Fig. 1, it is a kind of dimensional structure diagram of novel medicinal bottle stopper for lyophilized powder formulation provided by the utility model.This is new Type medicinal bottle stopper for lyophilized powder formulation includes lid 1 and from the vertically extending cock body 2 of the middle side part of lid 1 one.
Lid 1 is quality of rubber materials, and rounded sheet.
The center bottom of cock body 2 from lid 1 extends vertically, and is also quality of rubber materials.The center bottom of cock body 2 is provided inwardly with Circular groove 21, the internal diameter of groove 21 account for the 20%-30% of the external diameter of cock body 2.The peripheral edge of groove 21 to cock body 2 is provided with One air channel 22 connected with groove 21, and cock body 2 is tangent in two sides where air channel 22 and groove 21, air channel 22 External margin where circular arc account for the 15%-25% of 2 peripheral circular arc of cock body.Air channel 22 upwardly extends from the bottom of cock body 2, The depth of air channel 22 is small compared with the depth of groove 21.The outer wall of cock body 2 is provided with some double wedges 23, and the bottom margin of cock body 2 is set There are 3 ° of guide angles.In the present embodiment, the internal diameter of groove 21 accounts for the 25% of the external diameter of cock body 2, the external margin place of air channel 22 Circular arc account for the 20% of 2 peripheral circular arc of cock body, in this way, ensure medicine bottle in vapor can be evaporated while, also can Ensure physical stability of the bottle stopper on medicine bottle.
In freeze drying powder injection production process, first lid 1 is covered at the double wedge 23 of medicine bottle up to cock body 2, now medicine bottle In semitight state, vapor can be extracted from air channel 22, so both ensure that the health of decoction, and and can enough steams water Gas is quickly extracted, and shortens the lyophilized time.After having freezed, directly gently compressing lid 1 can be fully sealed, and realize quick Sterile vacuum is packed, and improves product quality and efficiency.
In this way, the novel medicinal bottle stopper for lyophilized powder formulation is simple in construction, easy to use, it can make medicine bottle that there is good air-tightness, Freeze drying powder injection production and packaging process in have effect it is good, on engine efficiency it is high the advantages of, be advantageous to the quick of medicine Sterile vacuum is packed, and improves product quality and efficiency.
It is to be appreciated that only offering an air channel 22 on cock body 2, ensureing that the vapor in medicine bottle can be steamed While hair falls, physical stability of the bottle stopper on medicine bottle also can guarantee that.In addition, the outer wall of cock body 2 be provided with it is some Double wedge 23 can also be changed to the continuous raised line around the outer wall of cock body 2.
Preferred embodiment of the present utility model is the foregoing is only, it is all in this practicality not to limit the utility model Within new spirit and principle, any modification, equivalent substitution and improvements made etc., guarantor of the present utility model should be included in Within the scope of shield.

Claims (6)

  1. A kind of 1. novel medicinal bottle stopper for lyophilized powder formulation, it is characterised in that:The plug for the cylindrical shape being connected including lid and with the lid Body, the center bottom of the cock body from the lid extend vertically, and the center bottom of the cock body is provided inwardly with the groove of circle, The internal diameter of the groove accounts for the 20%-30% of the cock body external diameter, and the peripheral edge of the groove to the cock body is provided with one The air channel connected with the groove, the air channel upwardly extend from the bottom of the cock body, and the depth of the air channel Depth compared with the groove is small, and the cock body is tangent in two sides where the air channel and the groove, and the ventilation Circular arc where the external margin of groove accounts for the 15%-30% of cock body periphery circular arc.
  2. A kind of 2. novel medicinal bottle stopper for lyophilized powder formulation as claimed in claim 1, it is characterised in that:The lid and cock body are rubber Material.
  3. A kind of 3. novel medicinal bottle stopper for lyophilized powder formulation as claimed in claim 1, it is characterised in that:If the outer wall of the cock body is provided with Dry double wedge.
  4. A kind of 4. novel medicinal bottle stopper for lyophilized powder formulation as claimed in claim 1, it is characterised in that:The bottom margin of the cock body is provided with 3 ° of guide angles.
  5. A kind of 5. novel medicinal bottle stopper for lyophilized powder formulation as claimed in claim 1, it is characterised in that:The internal diameter of the groove accounts for the plug The 25% of external footpath.
  6. A kind of 6. novel medicinal bottle stopper for lyophilized powder formulation as claimed in claim 1, it is characterised in that:The external margin institute of the air channel Circular arc account for the 20% of cock body periphery circular arc.
CN201720732088.5U 2017-06-22 2017-06-22 A kind of novel medicinal bottle stopper for lyophilized powder formulation Active CN206984712U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201720732088.5U CN206984712U (en) 2017-06-22 2017-06-22 A kind of novel medicinal bottle stopper for lyophilized powder formulation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201720732088.5U CN206984712U (en) 2017-06-22 2017-06-22 A kind of novel medicinal bottle stopper for lyophilized powder formulation

Publications (1)

Publication Number Publication Date
CN206984712U true CN206984712U (en) 2018-02-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201720732088.5U Active CN206984712U (en) 2017-06-22 2017-06-22 A kind of novel medicinal bottle stopper for lyophilized powder formulation

Country Status (1)

Country Link
CN (1) CN206984712U (en)

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